locus-tag	class	description
H7A86_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H7A86_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H7A86_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H7A86_RS00030	ENOG4108K0D	peptidase, M48
H7A86_RS00075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H7A86_RS00090	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
H7A86_RS00105	ENOG4105C5I	Dehydrogenase
H7A86_RS00110	ENOG4105CN1	protease
H7A86_RS00115	ENOG41063SB	peptidase
H7A86_RS00125	ENOG4107VAM	peptidase, m28
H7A86_RS00150	ENOG4105DQ4	alcohol dehydrogenase
H7A86_RS00160	ENOG4105BZ8	glutamate synthase
H7A86_RS00165	ENOG4105CBC	glutamate synthase
H7A86_RS00180	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H7A86_RS00205	ENOG4105EXG	Transcriptional regulator
H7A86_RS00215	ENOG4105E2V	Glycosyltransferase 36
H7A86_RS00230	ENOG4108I5C	dEAD DEAH box helicase
H7A86_RS00235	ENOG4108UT2	hemolysin iii
H7A86_RS00270	ENOG4105C9K	Endothelin-converting enzyme 1
H7A86_RS00280	ENOG4105CC0	LysR family Transcriptional regulator
H7A86_RS00350	ENOG4105KVH	Transcriptional regulator
H7A86_RS00385	ENOG4105E09	nadh pyrophosphatase
H7A86_RS00400	ENOG4105K63	Thioredoxin
H7A86_RS00410	ENOG4105CSH	Transporter
H7A86_RS00455	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H7A86_RS00480	ENOG4105CIR	epoxide hydrolase
H7A86_RS00515	ENOG4105CGF	Aromatic amino acid aminotransferase
H7A86_RS00520	ENOG4105CHB	tonB-dependent Receptor
H7A86_RS00530	ENOG41082W1	Cupin 2, conserved barrel domain protein
H7A86_RS00545	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
H7A86_RS00550	ENOG4105C26	Dehydrogenase
H7A86_RS00575	ENOG4105DQE	DNA ligase
H7A86_RS00580	ENOG4105DMF	Dehydrogenase
H7A86_RS00585	ENOG4105BZU	Histidine kinase
H7A86_RS00590	ENOG4105WH1	Two component transcriptional regulator luxr family
H7A86_RS00605	ENOG4108YAB	Invasion protein
H7A86_RS00610	ENOG4105RKW	reductase (By
H7A86_RS00750	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
H7A86_RS00755	ENOG4105CG3	alpha amylase, catalytic region
H7A86_RS00760	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H7A86_RS00795	ENOG4107TDE	lipolytic protein G-D-S-L family
H7A86_RS00800	ENOG4105EBR	Carboxylesterase
H7A86_RS00815	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H7A86_RS00825	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H7A86_RS00830	ENOG4105DSG	hydrolase family 43
H7A86_RS00835	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS00840	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
H7A86_RS00845	ENOG4105CHR	reductase
H7A86_RS00855	ENOG4107TDE	lipolytic protein G-D-S-L family
H7A86_RS00875	ENOG4105MIR	Phenylalanine 4-monooxygenase
H7A86_RS00880	ENOG4108YXU	transcriptional regulator AsnC family
H7A86_RS00885	ENOG4105CNM	Receptor
H7A86_RS00890	ENOG4105D78	K07001 NTE family protein
H7A86_RS00900	ENOG4105DKW	ABC transporter
H7A86_RS00915	ENOG4108IJ8	ABC transporter
H7A86_RS00920	ENOG4105E90	ABC transporter
H7A86_RS00935	ENOG41067HS	methyltransferase
H7A86_RS00965	ENOG4105D1F	ATP-binding protein
H7A86_RS00970	ENOG4105M4E	phosphohistidine phosphatase, SixA
H7A86_RS00980	ENOG4107RZC	phospholipase d
H7A86_RS00985	ENOG4105KA0	thioesterase Superfamily protein
H7A86_RS01005	ENOG4108V1U	phospholipid-binding protein
H7A86_RS01015	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
H7A86_RS01020	ENOG4105C5F	glutamine synthetase
H7A86_RS01030	ENOG4105BZU	Histidine kinase
H7A86_RS01035	ENOG4105CUX	Signal transduction histidine kinase
H7A86_RS01040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H7A86_RS01045	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H7A86_RS01050	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H7A86_RS01055	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
H7A86_RS01065	ENOG4105CHU	acetyl-coa acetyltransferase
H7A86_RS01105	ENOG4107YZP	Rhodanese domain protein
H7A86_RS01115	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
H7A86_RS01125	ENOG4105C7K	acetolactate synthase
H7A86_RS01130	ENOG4108TQ9	Histidine kinase
H7A86_RS01155	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H7A86_RS01170	ENOG4105E2T	synthase III
H7A86_RS01175	ENOG4107R3N	Filamentation induced by cAMP protein fic
H7A86_RS01180	ENOG4108J2P	Alpha beta hydrolase fold
H7A86_RS01185	ENOG4105PI0	Ferredoxin
H7A86_RS01190	ENOG410680H	amp-dependent synthetase and ligase
H7A86_RS01195	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
H7A86_RS01210	ENOG4105CPF	Cell wall formation (By similarity)
H7A86_RS01220	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
H7A86_RS01230	ENOG4105DR9	pseudouridine synthase
H7A86_RS01240	ENOG4108YZN	class I peptide chain release factor
H7A86_RS01250	ENOG4105D44	asparaginase
H7A86_RS01255	ENOG4105DGW	oligopeptidase A
H7A86_RS01260	ENOG4105C3F	Signal peptidase i
H7A86_RS01285	ENOG4107QP3	malate synthase g
H7A86_RS01295	ENOG4105BZU	Histidine kinase
H7A86_RS01325	ENOG4107QX3	carboxylase
H7A86_RS01330	ENOG4105C1G	acyl-Coa dehydrogenase
H7A86_RS01385	ENOG4105CKI	cobalamin synthesis protein
H7A86_RS01395	ENOG4108TZV	Membrane
H7A86_RS01405	ENOG4105D6Z	AFG1 family ATPase
H7A86_RS01415	ENOG4105K56	Transcriptional regulator
H7A86_RS01420	ENOG4108ZHJ	Organic hydroperoxide resistance protein
H7A86_RS01445	ENOG4105CV8	reductase
H7A86_RS01450	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
H7A86_RS01455	ENOG4105CPC	Aldo Keto reductase
H7A86_RS01465	ENOG4108R99	pseudouridine synthase
H7A86_RS01475	ENOG4105CQ7	ATP-dependent helicase
H7A86_RS01480	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS01490	ENOG4108W15	Protein of unknown function (DUF1456)
H7A86_RS01495	ENOG4105VT2	5-hydroxyisourate hydrolase
H7A86_RS01500	ENOG4105E1J	oxidoreductase
H7A86_RS01520	ENOG4105C5R	Aminotransferase
H7A86_RS01535	ENOG4105EQ2	LysR family Transcriptional regulator
H7A86_RS01540	ENOG4107RTG	Major Facilitator superfamily
H7A86_RS01550	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
H7A86_RS01580	ENOG4105ETT	transcriptional Regulator, LysR family
H7A86_RS01585	ENOG4105F8V	Hydrolase, tatD family
H7A86_RS01595	ENOG4106NZI	LysR family Transcriptional regulator
H7A86_RS01600	ENOG4105D94	Major Facilitator Superfamily
H7A86_RS01620	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H7A86_RS01625	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H7A86_RS01645	ENOG4106UW1	Major Facilitator superfamily
H7A86_RS01655	ENOG4105DAE	Methylenetetrahydrofolate reductase
H7A86_RS01660	ENOG4105WPN	DNA integration recombination invertion protein
H7A86_RS01665	ENOG4105DZ2	Transcriptional regulator
H7A86_RS01670	ENOG4108UZX	fmn reductase
H7A86_RS01690	ENOG4105ECR	NmrA family
H7A86_RS01705	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS01765	ENOG4105C01	Dihydroxy-acid dehydratase
H7A86_RS01780	ENOG4108Z0R	Transferase
H7A86_RS01785	ENOG4105D2S	major facilitator superfamily
H7A86_RS01790	ENOG4105CPI	Metal Dependent Phosphohydrolase
H7A86_RS01820	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
H7A86_RS01830	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H7A86_RS01835	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H7A86_RS01840	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H7A86_RS01845	ENOG4105E98	transcriptional regulator DeoR family
H7A86_RS01875	ENOG4105CHU	acetyl-coa acetyltransferase
H7A86_RS01890	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
H7A86_RS01895	ENOG4105F2Z	3-oxoadipate enol-lactonase
H7A86_RS01900	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
H7A86_RS01910	ENOG4107HP6	Transcriptional regulator
H7A86_RS01925	ENOG4105MH3	Protein of unknown function (DUF2490)
H7A86_RS01930	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H7A86_RS01970	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
H7A86_RS01980	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
H7A86_RS01985	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
H7A86_RS01990	ENOG41081UC	Inherit from COG: Competence protein
H7A86_RS01995	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
H7A86_RS02030	ENOG4105EGS	Mechanosensitive ion channel
H7A86_RS02045	ENOG4105CKW	Inner membrane protein yedI
H7A86_RS02055	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
H7A86_RS02060	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H7A86_RS02065	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H7A86_RS02090	ENOG4105K4T	epimerase
H7A86_RS02130	ENOG4105BZS	acriflavin resistance protein
H7A86_RS02140	ENOG4107GJV	short-chain dehydrogenase reductase
H7A86_RS02145	ENOG4105KVH	Transcriptional regulator
H7A86_RS02155	ENOG4105C1J	atp-dependent rna helicase
H7A86_RS02160	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
H7A86_RS02170	ENOG4105CPP	Dehydrogenase, E1 component
H7A86_RS02175	ENOG4107RUY	(E1 component), alpha subunit
H7A86_RS02190	ENOG4105DUX	Transporter
H7A86_RS02205	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
H7A86_RS02210	ENOG4105F1J	Homogentisate 1,2-dioxygenase
H7A86_RS02220	ENOG4105KJM	monovalent cation h antiporter subunit g
H7A86_RS02225	ENOG4105W4C	monovalent cation H antiporter subunit F
H7A86_RS02235	ENOG4107R4Z	monovalent cation h antiporter subunit d
H7A86_RS02240	ENOG4108ZE9	Monovalent cation H antiporter subunit C
H7A86_RS02245	ENOG4105D65	subunit l
H7A86_RS02280	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
H7A86_RS02300	ENOG4107TE5	Lipid kinase
H7A86_RS02305	ENOG4105CRQ	synthase (Component I)
H7A86_RS02320	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
H7A86_RS02330	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS02335	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H7A86_RS02340	ENOG4105CPQ	Dehydrogenase
H7A86_RS02345	ENOG4105CEP	NADH dehydrogenase
H7A86_RS02365	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS02375	ENOG4105R1U	AraC Family Transcriptional Regulator
H7A86_RS02390	ENOG4105K56	Transcriptional regulator
H7A86_RS02405	ENOG4105DDQ	anthranilate synthase
H7A86_RS02415	ENOG4108I0Q	anthranilate phosphoribosyltransferase
H7A86_RS02430	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
H7A86_RS02455	ENOG4108UJD	30S ribosomal protein S9
H7A86_RS02470	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H7A86_RS02480	ENOG4108UQY	Iron-storage protein
H7A86_RS02485	ENOG4105BZU	Histidine kinase
H7A86_RS02510	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
H7A86_RS02525	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
H7A86_RS02555	ENOG4105EM2	membrane
H7A86_RS02560	ENOG4105C12	Phosphoribosylglycinamide synthetase
H7A86_RS02565	ENOG4105DC1	bifunctional purine biosynthesis protein purh
H7A86_RS02580	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
H7A86_RS02600	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
H7A86_RS02615	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H7A86_RS02625	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H7A86_RS02630	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H7A86_RS02635	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
H7A86_RS02640	ENOG4105VF7	tolerance protein
H7A86_RS02645	ENOG4108K8S	endonuclease I
H7A86_RS02655	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
H7A86_RS02670	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H7A86_RS02695	ENOG4108S3W	Anti-feci sigma factor, fecr
H7A86_RS02720	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
H7A86_RS02745	ENOG4108YYC	ycei family
H7A86_RS02750	ENOG4105Q26	Siderophore-interacting protein
H7A86_RS02765	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
H7A86_RS02780	ENOG41065ZS	Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme- A to the apo- acyl-carrier-protein of the malonate decarboxylase to yield holo- acyl-carrier-protein (By similarity)
H7A86_RS02800	ENOG4105DRR	Transcriptional regulator, GntR family
H7A86_RS02805	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H7A86_RS02840	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
H7A86_RS02845	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
H7A86_RS02865	ENOG4105C4R	Atp-dependent dna helicase
H7A86_RS02945	ENOG4108SF5	RNA Polymerase
H7A86_RS02955	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS03020	ENOG4105CHF	Glutathione S-transferase
H7A86_RS03060	ENOG4105C5Z	peptidase
H7A86_RS03065	ENOG4107QS8	(LipO)protein
H7A86_RS03070	ENOG4105BZU	Histidine kinase
H7A86_RS03090	ENOG4105DFI	Membrane
H7A86_RS03095	ENOG4105F87	Dehydratase
H7A86_RS03155	ENOG4105BZU	Histidine kinase
H7A86_RS03160	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS03165	ENOG4106R7G	Glycoside hydrolase family 5
H7A86_RS03170	ENOG4105CHH	sulfate transporter
H7A86_RS03175	ENOG4105BZU	Histidine kinase
H7A86_RS03185	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
H7A86_RS03195	ENOG4108HRK	Histidine kinase
H7A86_RS03200	ENOG4108NEV	two component transcriptional regulator, LytTR family
H7A86_RS03205	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H7A86_RS03245	ENOG4105WD1	Membrane
H7A86_RS03255	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H7A86_RS03275	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
H7A86_RS03280	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
H7A86_RS03305	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H7A86_RS03310	ENOG4105BZU	Histidine kinase
H7A86_RS03315	ENOG4105CD8	aminopeptidase N
H7A86_RS03330	ENOG4105DZG	Dehydrogenase
H7A86_RS03335	ENOG4108Q1J	Extracellular solute-binding protein, family 3
H7A86_RS03360	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
H7A86_RS03365	ENOG4107T4Z	adenosine kinase
H7A86_RS03375	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
H7A86_RS03390	ENOG4105CNI	cell division protein FtsW
H7A86_RS03395	ENOG4107WN4	Polygalacturonase
H7A86_RS03400	ENOG4105CVE	Lytic murein transglycosylase
H7A86_RS03405	ENOG4105K6T	rare lipoprotein A
H7A86_RS03410	ENOG4105DZ1	carboxypeptidase
H7A86_RS03430	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
H7A86_RS03435	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
H7A86_RS03440	ENOG4105CN1	protease
H7A86_RS03495	ENOG4108J5G	6-phosphogluconate dehydrogenase
H7A86_RS03500	ENOG4105D9R	oxidoreductase
H7A86_RS03505	ENOG4105W4M	Transport-associated protein
H7A86_RS03510	ENOG4105BZU	Histidine kinase
H7A86_RS03520	ENOG4105BZU	Histidine kinase
H7A86_RS03530	ENOG410642E	Short chain dehydrogenase
H7A86_RS03565	ENOG4105GVR	general secretion pathway protein D
H7A86_RS03570	ENOG4107QHF	type ii secretion system protein e
H7A86_RS03575	ENOG4105D7Q	type ii secretion system
H7A86_RS03580	ENOG4108VAU	general secretion pathway protein G
H7A86_RS03585	ENOG4105VWV	general secretion pathway protein h
H7A86_RS03590	ENOG4105X5Z	General secretion pathway protein I
H7A86_RS03625	ENOG4105CNT	hydrolase family 2
H7A86_RS03650	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS03655	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H7A86_RS03660	ENOG4105CE4	GlcNAc 6-P deacetylase
H7A86_RS03675	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H7A86_RS03685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS03690	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
H7A86_RS03700	ENOG4105C94	Transporter
H7A86_RS03710	ENOG4108Z33	Thiol disulfide Interchange Protein
H7A86_RS03720	ENOG4106RE7	Cytochrome
H7A86_RS03725	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
H7A86_RS03730	ENOG4105CY0	Metallo-Beta-Lactamase
H7A86_RS03745	ENOG4105JJR	Histidine kinase
H7A86_RS03765	ENOG410903D	sensor protein
H7A86_RS03780	ENOG4108QBQ	Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione (By similarity)
H7A86_RS03785	ENOG4105C4W	S-formylglutathione hydrolase
H7A86_RS03790	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H7A86_RS03810	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
H7A86_RS03815	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
H7A86_RS03825	ENOG4105C08	Histidine kinase
H7A86_RS03830	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
H7A86_RS03835	ENOG4105CQB	FAD linked oxidase domain protein
H7A86_RS03840	ENOG4105S2T	inner membrane protein YbcI
H7A86_RS03875	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H7A86_RS03880	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
H7A86_RS03885	ENOG4105CJN	penicillin-binding protein
H7A86_RS03890	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H7A86_RS03895	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
H7A86_RS03915	ENOG4105DFU	Cell wall formation (By similarity)
H7A86_RS03920	ENOG4105CPF	Cell wall formation (By similarity)
H7A86_RS03925	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
H7A86_RS03930	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
H7A86_RS03935	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H7A86_RS03940	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H7A86_RS03950	ENOG4105DR5	peptidase
H7A86_RS03955	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H7A86_RS03965	ENOG4105M6F	mutator MutT protein
H7A86_RS03980	ENOG4105SYT	Methylenetetrahydrofolate reductase
H7A86_RS04025	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
H7A86_RS04035	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
H7A86_RS04055	ENOG4105D6F	Phosphatase
H7A86_RS04075	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H7A86_RS04080	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H7A86_RS04090	ENOG4105D9N	nucleoside
H7A86_RS04095	ENOG4105CPC	Aldo Keto reductase
H7A86_RS04105	ENOG4105D05	Receptor
H7A86_RS04125	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
H7A86_RS04140	ENOG4105E2B	Taurine dioxygenase
H7A86_RS04150	ENOG4108I0Y	(ABC) transporter
H7A86_RS04155	ENOG4108UJV	acyl-CoA thioesterase i
H7A86_RS04165	ENOG4105DHQ	Histidine kinase
H7A86_RS04175	ENOG41080IJ	Diacylglycerol kinase
H7A86_RS04210	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
H7A86_RS04215	ENOG4105NWN	ApaG protein
H7A86_RS04220	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H7A86_RS04235	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
H7A86_RS04245	ENOG4108WBT	adenosyltransferase
H7A86_RS04255	ENOG4105D0A	hydroxylase
H7A86_RS04260	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
H7A86_RS04295	ENOG4105DDW	LysR family Transcriptional regulator
H7A86_RS04300	ENOG4105CEY	Amp-dependent synthetase and ligase
H7A86_RS04310	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
H7A86_RS04360	ENOG4105DXC	membrane
H7A86_RS04365	ENOG4105CX6	glutaminyL-tRNA synthetase
H7A86_RS04385	ENOG4105BZU	Histidine kinase
H7A86_RS04390	ENOG4105WH1	Two component transcriptional regulator luxr family
H7A86_RS04400	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H7A86_RS04410	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H7A86_RS04415	ENOG4105NXH	GreA GreB family elongation factor
H7A86_RS04420	ENOG4105C5Q	Transcriptional regulator
H7A86_RS04435	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H7A86_RS04455	ENOG4105C2M	dna polymerase I
H7A86_RS04485	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H7A86_RS04505	ENOG4105W8H	transhydrogenase (subunit alpha
H7A86_RS04510	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H7A86_RS04525	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H7A86_RS04530	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
H7A86_RS04535	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
H7A86_RS04540	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
H7A86_RS04545	ENOG4108Z66	YbaK ebsC protein
H7A86_RS04560	ENOG4105CS1	NAD(P)H quinone oxidoreductase
H7A86_RS04565	ENOG4107S2Z	UPF0761 membrane protein
H7A86_RS04570	ENOG4107QX9	Thiol disulfide interChange protein
H7A86_RS04585	ENOG4105CSR	polyphosphate kinase 2
H7A86_RS04590	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
H7A86_RS04605	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
H7A86_RS04610	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
H7A86_RS04615	ENOG4105QVB	outer membrane lipoprotein LolB
H7A86_RS04630	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H7A86_RS04635	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
H7A86_RS04640	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
H7A86_RS04645	ENOG4105C3G	gtp-binding protein
H7A86_RS04665	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H7A86_RS04675	ENOG4105PM1	preprotein translocase subunit SecE
H7A86_RS04680	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
H7A86_RS04685	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H7A86_RS04690	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
H7A86_RS04695	ENOG4108VZM	50s ribosomal protein L10
H7A86_RS04700	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H7A86_RS04710	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H7A86_RS04725	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H7A86_RS04730	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H7A86_RS04735	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
H7A86_RS04755	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7A86_RS04770	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H7A86_RS04785	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
H7A86_RS04795	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H7A86_RS04835	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H7A86_RS04840	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H7A86_RS04870	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
H7A86_RS04875	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
H7A86_RS04885	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H7A86_RS04895	ENOG4105CI3	gtp-binding protein typa
H7A86_RS04900	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
H7A86_RS04905	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H7A86_RS04910	ENOG4108K3A	Glutathione S-transferase
H7A86_RS04925	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H7A86_RS04930	ENOG4105CIS	alcohol dehydrogenase
H7A86_RS04935	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
H7A86_RS04945	ENOG4108R99	pseudouridine synthase
H7A86_RS04955	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
H7A86_RS04960	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H7A86_RS04965	ENOG4108I5D	sulfate abc transporter
H7A86_RS04975	ENOG4108IJ6	ABC transporter
H7A86_RS04985	ENOG4105CPQ	Dehydrogenase
H7A86_RS04995	ENOG4105HSS	phospholipase C
H7A86_RS05005	ENOG4105CVJ	phosphoglycerate mutase
H7A86_RS05015	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H7A86_RS05030	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H7A86_RS05035	ENOG4105ED9	Protein of unknown function (DUF455)
H7A86_RS05040	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
H7A86_RS05050	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
H7A86_RS05055	ENOG4105EYK	Phosphatidylglycerophosphatase B
H7A86_RS05060	ENOG4105BZF	Glycosyl transferase (Group 1
H7A86_RS05065	ENOG4105C9X	ppx gppa phosphatase
H7A86_RS05070	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H7A86_RS05075	ENOG4105BZU	Histidine kinase
H7A86_RS05080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H7A86_RS05085	ENOG4105ERG	peptidase m48, ste24p
H7A86_RS05090	ENOG4105VW4	glutaredoxin 3
H7A86_RS05100	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H7A86_RS05265	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H7A86_RS05435	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H7A86_RS05445	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H7A86_RS05475	ENOG4105EIN	peptidylprolyl cis-trans isomerase
H7A86_RS05480	ENOG41068JE	domain protein
H7A86_RS05485	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H7A86_RS05495	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H7A86_RS05500	ENOG4107RZZ	dna polymerase iii epsilon subunit
H7A86_RS05505	ENOG4108ZF3	Phosphatase
H7A86_RS05520	ENOG4105DKP	glycosyl transferase, family 9
H7A86_RS05530	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
H7A86_RS05535	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H7A86_RS05540	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H7A86_RS05545	ENOG4105M00	molybdopterin converting factor, subunit 1
H7A86_RS05550	ENOG4108ZAF	Molybdopterin
H7A86_RS05565	ENOG4107QMP	dna polymerase iii subunits gamma and tau
H7A86_RS05570	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
H7A86_RS05575	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
H7A86_RS05580	ENOG4105K59	histidine triad (HIT) protein
H7A86_RS05590	ENOG4105F8C	transglutaminase domain-containing protein
H7A86_RS05600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H7A86_RS05610	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
H7A86_RS05620	ENOG4108UHJ	MAF-like protein
H7A86_RS05625	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
H7A86_RS05630	ENOG4105VGS	50s ribosomal protein l32
H7A86_RS05635	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H7A86_RS05645	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
H7A86_RS05650	ENOG4105CHR	reductase
H7A86_RS05660	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H7A86_RS05670	ENOG4105HHA	aminodeoxychorismate lyase
H7A86_RS05675	ENOG4107QRG	dna polymerase iii
H7A86_RS05695	ENOG4108JU7	Transcriptional regulator
H7A86_RS05700	ENOG4105CR4	methylisocitrate lyase
H7A86_RS05705	ENOG4105BZN	citrate synthase
H7A86_RS05715	ENOG4108I0Z	Aconitate hydratase
H7A86_RS05720	ENOG4105YAJ	CopG Arc MetJ
H7A86_RS05730	ENOG4105C7F	AcnD-accessory protein PrpF
H7A86_RS05745	ENOG4105DN3	alpha-2-macroglobulin domain protein
H7A86_RS05775	ENOG4108JQB	penicillin-binding protein 1C
H7A86_RS05800	ENOG4105M3Z	response regulator
H7A86_RS05805	ENOG4107QJR	hflk protein
H7A86_RS05810	ENOG4105EPW	hflc protein
H7A86_RS05850	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
H7A86_RS05855	ENOG4108XFH	Transcriptional regulator
H7A86_RS05865	ENOG4105DZR	Type I site-specific deoxyribonuclease
H7A86_RS05900	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
H7A86_RS05910	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H7A86_RS05920	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H7A86_RS05930	ENOG4105CWX	Alpha-1,2-mannosidase
H7A86_RS05960	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
H7A86_RS05965	ENOG4105H67	Protein of unknown function (DUF421)
H7A86_RS05980	ENOG4105DPW	Major facilitator superfamily MFS_1
H7A86_RS05985	ENOG4105EY3	heparinase II III family protein
H7A86_RS06010	ENOG4105C7W	Xanthine dehydrogenase
H7A86_RS06015	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
H7A86_RS06020	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
H7A86_RS06070	ENOG4105EPD	Oligopeptide transporter, Opt family
H7A86_RS06085	ENOG4105TW1	Carbohydrate-selective porin OprB
H7A86_RS06090	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
H7A86_RS06115	ENOG4106AXJ	AraC family transcriptional regulator
H7A86_RS06125	ENOG4105CV8	reductase
H7A86_RS06130	ENOG4105EBR	Carboxylesterase
H7A86_RS06135	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7A86_RS06140	ENOG4105C2C	drug resistance transporter, Bcr CflA
H7A86_RS06160	ENOG4105DIJ	Phosphoethanolamine transferase
H7A86_RS06170	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
H7A86_RS06175	ENOG4105ETX	regulatoR
H7A86_RS06180	ENOG4105US7	Histidine kinase
H7A86_RS06200	ENOG4107QMS	site-determining protein
H7A86_RS06205	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
H7A86_RS06215	ENOG4105BZU	Histidine kinase
H7A86_RS06220	ENOG4105WH1	Two component transcriptional regulator luxr family
H7A86_RS06275	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
H7A86_RS06285	ENOG4105GFR	rna polymerase sigma factor
H7A86_RS06295	ENOG4105C29	acyl-CoA thioesterase
H7A86_RS06300	ENOG4105UPE	Enoyl-CoA hydratase
H7A86_RS06310	ENOG4108TGP	Thioesterase superfamily protein
H7A86_RS06315	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H7A86_RS06325	ENOG4105K46	50S ribosomal protein l27
H7A86_RS06340	ENOG4105CJR	Integral membrane protein (MviN
H7A86_RS06345	ENOG4105DTN	riboflavin biosynthesis protein ribF
H7A86_RS06355	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
H7A86_RS06360	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
H7A86_RS06370	ENOG4105E2S	oxidase) subunit II
H7A86_RS06375	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H7A86_RS06380	ENOG4105CCU	oxidase (Subunit III)
H7A86_RS06385	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
H7A86_RS06395	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H7A86_RS06400	ENOG4105KAF	membrAne
H7A86_RS06415	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
H7A86_RS06425	ENOG4107MMM	Anti-sigma-factor antagonist
H7A86_RS06430	ENOG4105FUA	antagonist
H7A86_RS06435	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
H7A86_RS06445	ENOG4105BZU	Histidine kinase
H7A86_RS06465	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
H7A86_RS06470	ENOG4105C08	Histidine kinase
H7A86_RS06475	ENOG4107Z5C	methylesterase
H7A86_RS06480	ENOG4105BZU	Histidine kinase
H7A86_RS06485	ENOG4105BZU	Histidine kinase
H7A86_RS06490	ENOG4105BZU	Histidine kinase
H7A86_RS06515	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
H7A86_RS06520	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
H7A86_RS06525	ENOG4105CRE	cytochrome C
H7A86_RS06530	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7A86_RS06535	ENOG4105EA8	2-Nitropropane dioxygenase
H7A86_RS06550	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H7A86_RS06555	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
H7A86_RS06565	ENOG4107QJQ	Mate efflux family protein
H7A86_RS06570	ENOG4105VEJ	Heat shock protein
H7A86_RS06575	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
H7A86_RS06585	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
H7A86_RS06590	ENOG4107Z3H	Transcriptional regulator, TetR family
H7A86_RS06605	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS06620	ENOG4108NEV	two component transcriptional regulator, LytTR family
H7A86_RS06630	ENOG4106NZI	LysR family Transcriptional regulator
H7A86_RS06635	ENOG4105C7K	acetolactate synthase
H7A86_RS06650	ENOG4105CNT	hydrolase family 2
H7A86_RS06655	ENOG4106FKC	arabinogalactan endo-1,4-beta-galactosidase
H7A86_RS06665	ENOG4105CFF	transcriptional regulator
H7A86_RS06670	ENOG4105C26	Dehydrogenase
H7A86_RS06675	ENOG4105C1G	acyl-Coa dehydrogenase
H7A86_RS06685	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H7A86_RS06690	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H7A86_RS06700	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H7A86_RS06705	ENOG4105EMN	RNA polymerase sigma factor
H7A86_RS06715	ENOG4105C0H	protease
H7A86_RS06725	ENOG4105C3F	Signal peptidase i
H7A86_RS06735	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
H7A86_RS06745	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
H7A86_RS06765	ENOG4107ZXU	DSBA oxidoreductase
H7A86_RS06770	ENOG4108QDE	fad dependent oxidoreductase
H7A86_RS06775	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
H7A86_RS06780	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
H7A86_RS06785	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
H7A86_RS06790	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
H7A86_RS06795	ENOG4105VEQ	Cold shock protein
H7A86_RS06800	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
H7A86_RS06810	ENOG4107QRT	dEAD DEAH box helicase
H7A86_RS06815	ENOG4107T0X	DNA ligase
H7A86_RS06825	ENOG4107T0X	DNA ligase
H7A86_RS06855	ENOG4105CHU	acetyl-coa acetyltransferase
H7A86_RS06875	ENOG4108VKG	metal-dependent hydrolase
H7A86_RS06890	ENOG4105KSC	Transcriptional regulator, TraR DksA family
H7A86_RS06905	ENOG4105DFF	Rod shape-determining protein mreb
H7A86_RS06910	ENOG4108YZY	peptidylprolyl cis-trans isomerase
H7A86_RS06920	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
H7A86_RS06940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H7A86_RS06945	ENOG4105F27	Major Facilitator
H7A86_RS06985	ENOG4105M4H	endoribonuclease L-psp
H7A86_RS06990	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
H7A86_RS07005	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
H7A86_RS07030	ENOG4105K6V	RNA polymerase
H7A86_RS07045	ENOG4108R3D	Electron transport complex
H7A86_RS07055	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H7A86_RS07070	ENOG4105DA5	(ABC) transporter
H7A86_RS07075	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
H7A86_RS07080	ENOG4108IQI	permease
H7A86_RS07085	ENOG4107QK5	Homocysteine s-methyltransferase
H7A86_RS07140	ENOG4108YXA	Membrane
H7A86_RS07155	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H7A86_RS07160	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H7A86_RS07165	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H7A86_RS07175	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H7A86_RS07190	ENOG4105DZP	Membrane-associated zinc metalloprotease
H7A86_RS07195	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
H7A86_RS07200	ENOG4105KNE	Phosphatidate cytidylyltransferase
H7A86_RS07205	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H7A86_RS07215	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H7A86_RS07225	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H7A86_RS07230	ENOG4105CE9	30S ribosomal protein S2
H7A86_RS07265	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H7A86_RS07270	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
H7A86_RS07285	ENOG4105KUZ	arsenate reductase
H7A86_RS07290	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H7A86_RS07300	ENOG4105CAQ	asparagine synthetase
H7A86_RS07310	ENOG4108ESX	Receptor
H7A86_RS07320	ENOG4108UWD	Iron-storage protein
H7A86_RS07325	ENOG4105FQ6	thiopurine methyltransferase
H7A86_RS07330	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H7A86_RS07350	ENOG4105CW7	secretion protein, HlyD family
H7A86_RS07355	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H7A86_RS07385	ENOG4105DUX	Transporter
H7A86_RS07415	ENOG4105DGW	oligopeptidase A
H7A86_RS07425	ENOG4105DP0	ferredoxin-NADP reductase
H7A86_RS07435	ENOG4107GFK	fumarate
H7A86_RS07450	ENOG4108V9Q	carbonic anhydrase
H7A86_RS07455	ENOG4105HDD	phospholipase
H7A86_RS07460	ENOG4105SXS	Protein of unknown function (DUF456)
H7A86_RS07465	ENOG4105VEQ	Cold shock protein
H7A86_RS07480	ENOG4105CUZ	uba thif-type nad fad binding protein
H7A86_RS07485	ENOG4105F8V	Hydrolase, tatD family
H7A86_RS07500	ENOG4105C1G	acyl-Coa dehydrogenase
H7A86_RS07510	ENOG4108RXX	maleylacetoacetate isomerase
H7A86_RS07515	ENOG4105CAQ	asparagine synthetase
H7A86_RS07525	ENOG4105CDU	Replicative dna helicase
H7A86_RS07530	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
H7A86_RS07535	ENOG4105CDV	Ompa motb domain protein
H7A86_RS07540	ENOG4105CR8	Transcriptional regulator
H7A86_RS07555	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H7A86_RS07575	ENOG4105BZU	Histidine kinase
H7A86_RS07585	ENOG4105BZU	Histidine kinase
H7A86_RS07635	ENOG4105W5Q	DNA repair protein (RadC
H7A86_RS07685	ENOG4105CHR	reductase
H7A86_RS07810	ENOG4105EYM	Major Facilitator superfamily
H7A86_RS07870	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
H7A86_RS07875	ENOG41090R7	Ferric uptake
H7A86_RS07880	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H7A86_RS07885	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
H7A86_RS07890	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7A86_RS07895	ENOG4105CFG	Acts as a chaperone (By similarity)
H7A86_RS07900	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H7A86_RS07935	ENOG4105C5Q	Transcriptional regulator
H7A86_RS07940	ENOG4105BZ1	(ABC) transporter
H7A86_RS07950	ENOG4108URH	decarboxylase
H7A86_RS07960	ENOG4105C7S	Dehydrogenase
H7A86_RS07965	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
H7A86_RS07975	ENOG4105EZE	Cupin 4 family protein
H7A86_RS07980	ENOG4107QTF	adenylosuccinate lyase
H7A86_RS07985	ENOG4105C37	(CBS) domain
H7A86_RS08015	ENOG4105CZV	ABC transporter
H7A86_RS08020	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
H7A86_RS08035	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H7A86_RS08040	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
H7A86_RS08060	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS08070	ENOG4105D7K	pfkb domain protein
H7A86_RS08080	ENOG4105C3R	Methionine synthase
H7A86_RS08085	ENOG4105C3R	Methionine synthase
H7A86_RS08090	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H7A86_RS08095	ENOG4105C1G	acyl-Coa dehydrogenase
H7A86_RS08115	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H7A86_RS08125	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H7A86_RS08135	ENOG4105BZU	Histidine kinase
H7A86_RS08140	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
H7A86_RS08150	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
H7A86_RS08155	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H7A86_RS08160	ENOG4105E2Z	phosphate ABC transporter (Permease
H7A86_RS08165	ENOG4105C8U	phosphate abc transporter
H7A86_RS08170	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
H7A86_RS08190	ENOG4107B2H	carbonic anhydrase
H7A86_RS08195	ENOG4105CHH	sulfate transporter
H7A86_RS08200	ENOG4105CSM	endonuclease III
H7A86_RS08210	ENOG4105E39	Enoyl-CoA hydratase
H7A86_RS08215	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H7A86_RS08220	ENOG4105P8F	nudix hydrolase
H7A86_RS08225	ENOG4105KHC	sulfurtransferase
H7A86_RS08260	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H7A86_RS08265	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
H7A86_RS08275	ENOG4105IH7	synthase
H7A86_RS08290	ENOG4105CJB	Exodeoxyribonuclease I
H7A86_RS08295	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
H7A86_RS08300	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
H7A86_RS08310	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
H7A86_RS08315	ENOG41077A9	carbonic anhydrase
H7A86_RS08335	ENOG4105C5S	asparaginyl-tRNA synthetase
H7A86_RS08340	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
H7A86_RS08365	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
H7A86_RS08375	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H7A86_RS08380	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H7A86_RS08385	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
H7A86_RS08400	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H7A86_RS08405	ENOG4105DZG	Dehydrogenase
H7A86_RS08420	ENOG4105CGP	Urocanate hydratase
H7A86_RS08430	ENOG4105C84	Histidine ammonia-lyase
H7A86_RS08470	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
H7A86_RS08475	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
H7A86_RS08480	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
H7A86_RS08490	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H7A86_RS08505	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H7A86_RS08510	ENOG4105CC0	LysR family Transcriptional regulator
H7A86_RS08530	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
H7A86_RS08540	ENOG4108SF5	RNA Polymerase
H7A86_RS08545	ENOG4108S3W	Anti-feci sigma factor, fecr
H7A86_RS08555	ENOG4105CA0	peroxidase
H7A86_RS08565	ENOG4105WD1	Membrane
H7A86_RS08570	ENOG4108YNN	Heme oxygenase
H7A86_RS08590	ENOG4108S3W	Anti-feci sigma factor, fecr
H7A86_RS08595	ENOG4108SF5	RNA Polymerase
H7A86_RS08605	ENOG4105W5Q	DNA repair protein (RadC
H7A86_RS08625	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
H7A86_RS08700	ENOG4108N8X	transition metal ion binding
H7A86_RS08710	ENOG4105DQE	DNA ligase
H7A86_RS08725	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS08740	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS08770	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS08790	ENOG4105CQZ	Histidine kinase
H7A86_RS08810	ENOG4105KWW	Biogenesis protein
H7A86_RS08815	ENOG4107QX9	Thiol disulfide interChange protein
H7A86_RS08820	ENOG4105DA4	cytochrome c-type biogenesis protein
H7A86_RS08825	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
H7A86_RS08835	ENOG41060IM	Heme exporter protein
H7A86_RS08850	ENOG4105EMN	RNA polymerase sigma factor
H7A86_RS08900	ENOG4105EGZ	biosynthesis protein
H7A86_RS08920	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H7A86_RS08930	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H7A86_RS08935	ENOG4107QPH	glycogen) synthase
H7A86_RS08940	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
H7A86_RS08955	ENOG4105EHU	Circadian clock protein KaiC
H7A86_RS08965	ENOG41079KZ	Major Facilitator Superfamily
H7A86_RS08970	ENOG4105DEN	Luciferase family
H7A86_RS09010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H7A86_RS09020	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H7A86_RS09025	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
H7A86_RS09030	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H7A86_RS09045	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
H7A86_RS09050	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
H7A86_RS09055	ENOG4108DG9	Smr protein MutS2
H7A86_RS09060	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
H7A86_RS09065	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H7A86_RS09070	ENOG4108UM1	dedA family
H7A86_RS09075	ENOG4108K5P	(LipO)protein
H7A86_RS09085	ENOG4105HBR	Rna-binding protein
H7A86_RS09090	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
H7A86_RS09095	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H7A86_RS09100	ENOG4105EEI	dihydropteroate synthase
H7A86_RS09115	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H7A86_RS09120	ENOG4107TH8	cina domain protein
H7A86_RS09130	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
H7A86_RS09140	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H7A86_RS09145	ENOG4105Y3E	Modulates RecA activity (By similarity)
H7A86_RS09150	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H7A86_RS09165	ENOG4107SDU	Methyl-accepting chemotaxis
H7A86_RS09175	ENOG4105CWB	LysR family transcriptional Regulator
H7A86_RS09200	ENOG4105DWF	phosphomethylpyrimidine kinase
H7A86_RS09215	ENOG4108IAB	Phoh family
H7A86_RS09220	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7A86_RS09235	ENOG4107TUS	Dihydrodipicolinate synthase
H7A86_RS09245	ENOG4108Z4U	Ferredoxin
H7A86_RS09250	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
H7A86_RS09265	ENOG4108RTU	Aldolase
H7A86_RS09310	ENOG4105CMG	Carbohydrate kinase
H7A86_RS09315	ENOG4105C93	Xylose Isomerase
H7A86_RS09340	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H7A86_RS09345	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
H7A86_RS09355	ENOG4105DJ0	Poly(A) Polymerase
H7A86_RS09360	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7A86_RS09365	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H7A86_RS09370	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
H7A86_RS09415	ENOG4105KU2	hydrolase family 5
H7A86_RS09420	ENOG4108UYB	regulatoR
H7A86_RS09430	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
H7A86_RS09435	ENOG410841Q	phosphoesterase PA-phosphatase related protein
H7A86_RS09450	ENOG4108SXK	Transporter Drug Metabolite Exporter family
H7A86_RS09455	ENOG4105D4A	Cell wall formation (By similarity)
H7A86_RS09475	ENOG4105C26	Dehydrogenase
H7A86_RS09505	ENOG4105CND	Glycosyl transferase, family 2
H7A86_RS09510	ENOG4107BJW	polysaccharide deacetylase
H7A86_RS09540	ENOG4108606	TspO/MBR family
H7A86_RS09545	ENOG4105CFH	Aspartokinase
H7A86_RS09570	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H7A86_RS09575	ENOG4105CUT	histidyl-tRNA synthetase
H7A86_RS09585	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
H7A86_RS09590	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
H7A86_RS09595	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H7A86_RS09600	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
H7A86_RS09605	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H7A86_RS09610	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H7A86_RS09620	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H7A86_RS09645	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
H7A86_RS09650	ENOG4105CUB	amino acid
H7A86_RS09655	ENOG4105CUB	amino acid
H7A86_RS09665	ENOG4108JQ1	Dehydrogenase
H7A86_RS09670	ENOG4105CQB	FAD linked oxidase domain protein
H7A86_RS09690	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H7A86_RS09700	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
H7A86_RS09715	ENOG4105CE1	Ferrous iron transport protein b
H7A86_RS09730	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H7A86_RS09735	ENOG4108RPX	mosc domain containing protein
H7A86_RS09745	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H7A86_RS09755	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H7A86_RS09760	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H7A86_RS09770	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H7A86_RS09795	ENOG4105CRK	lysyL-tRNA synthetase
H7A86_RS09800	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
H7A86_RS09805	ENOG4105BZU	Histidine kinase
H7A86_RS09810	ENOG41060WC	Enoyl-CoA hydratase
H7A86_RS09815	ENOG4105CEY	Amp-dependent synthetase and ligase
H7A86_RS09825	ENOG4107QM5	aconitate hydratase
H7A86_RS09840	ENOG4107QIJ	Aconitate hydratase 2
H7A86_RS09845	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
H7A86_RS09850	ENOG4105BZU	Histidine kinase
H7A86_RS09855	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H7A86_RS09865	ENOG4105BZU	Histidine kinase
H7A86_RS09870	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS09880	ENOG4108V3W	Chemotaxis protein, CheW
H7A86_RS09890	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS09900	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS09905	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS09910	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS09920	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS09940	ENOG4105CBS	Chea signal transduction histidine kinase
H7A86_RS09945	ENOG4108VYJ	response regulator receiver protein
H7A86_RS09955	ENOG4108V3W	Chemotaxis protein, CheW
H7A86_RS09965	ENOG4105ER2	Ompa motb domain protein
H7A86_RS09970	ENOG4105E14	MotA TolQ exbB proton channel
H7A86_RS09980	ENOG4105EJC	lysr family transcriptional regulator
H7A86_RS09985	ENOG4105F27	Major Facilitator
H7A86_RS09990	ENOG4105CHR	reductase
H7A86_RS10050	ENOG4108VYJ	response regulator receiver protein
H7A86_RS10055	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H7A86_RS10065	ENOG4105FZW	flagellar biosynthesis regulator FlhF
H7A86_RS10070	ENOG4105D7B	Flagellar biosynthesis protein flha
H7A86_RS10075	ENOG4105D00	flagellar biosynthetic protein flhB
H7A86_RS10080	ENOG4105BZU	Histidine kinase
H7A86_RS10085	ENOG4105BZU	Histidine kinase
H7A86_RS10090	ENOG4105BZU	Histidine kinase
H7A86_RS10095	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
H7A86_RS10100	ENOG4105VS8	Flagellar biosynthetic protein fliq
H7A86_RS10105	ENOG4105CN7	Flagellar biosynthetic protein FliP
H7A86_RS10110	ENOG4105VTB	flagellar biosynthesis protein fliO
H7A86_RS10115	ENOG4105DD5	Flagellar motor switch protein
H7A86_RS10120	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
H7A86_RS10140	ENOG4108JIR	Flagellum-specific ATP synthase
H7A86_RS10150	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
H7A86_RS10155	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
H7A86_RS10160	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
H7A86_RS10175	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
H7A86_RS10205	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
H7A86_RS10210	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
H7A86_RS10215	ENOG4108P1X	synthase
H7A86_RS10235	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H7A86_RS10240	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H7A86_RS10260	ENOG4105MQ3	flagellar protein FliS
H7A86_RS10265	ENOG4107W9T	flagellar hook-associated
H7A86_RS10270	ENOG4105I03	Flagellin
H7A86_RS10285	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
H7A86_RS10290	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
H7A86_RS10300	ENOG4105CGA	flagellar basal-body rod protein FlgG
H7A86_RS10305	ENOG4108KPB	Flagellar basal-body rod protein FlgF
H7A86_RS10310	ENOG4105BZE	flagellar hook protein, FlgE
H7A86_RS10315	ENOG410822I	Flagellar hook capping protein
H7A86_RS10320	ENOG4108ZC9	flagellar basal-body rod protein flgc
H7A86_RS10350	ENOG4105BZU	Histidine kinase
H7A86_RS10355	ENOG4105BZU	Histidine kinase
H7A86_RS10365	ENOG4105BZU	Histidine kinase
H7A86_RS10380	ENOG41075W9	High frequency lysogenization protein HflD homolog
H7A86_RS10385	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H7A86_RS10400	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
H7A86_RS10405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H7A86_RS10415	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
H7A86_RS10425	ENOG4105C3M	thioredoxin reductase
H7A86_RS10430	ENOG4105CNU	cell division protein FtsK
H7A86_RS10445	ENOG4105D1H	recombination factor protein RarA
H7A86_RS10450	ENOG41082MI	Protein CrcB homolog
H7A86_RS10455	ENOG4105CHU	acetyl-coa acetyltransferase
H7A86_RS10485	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
H7A86_RS10495	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
H7A86_RS10500	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H7A86_RS10505	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H7A86_RS10510	ENOG4105D06	uba thif-type nad fad binding protein
H7A86_RS10525	ENOG4105CGK	Exodeoxyribonuclease III
H7A86_RS10535	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H7A86_RS10540	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
H7A86_RS10550	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H7A86_RS10560	ENOG4105I5W	Transporter
H7A86_RS10570	ENOG4108IFG	nitrite reductase, (NAD(P)H)
H7A86_RS10585	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H7A86_RS10610	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
H7A86_RS10620	ENOG4105D5U	fad dependent oxidoreductase
H7A86_RS10685	ENOG4105CQZ	Histidine kinase
H7A86_RS10730	ENOG410642W	LysR family Transcriptional regulator
H7A86_RS10760	ENOG4105CC0	LysR family Transcriptional regulator
H7A86_RS10770	ENOG4105FFC	UPF0187 protein
H7A86_RS10795	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
H7A86_RS10905	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H7A86_RS10915	ENOG4107W2A	UPF0173 metal-dependent hydrolase
H7A86_RS10930	ENOG4105CUJ	penicillin amidase
H7A86_RS10935	ENOG4105IBP	Cyclic peptide transporter
H7A86_RS10955	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H7A86_RS11015	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
H7A86_RS11020	ENOG4105EI2	Pseudouridine synthase
H7A86_RS11025	ENOG4105C03	ribonuclease
H7A86_RS11030	ENOG4105WH1	Two component transcriptional regulator luxr family
H7A86_RS11045	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H7A86_RS11055	ENOG4107QQG	Dehydrogenase
H7A86_RS11080	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
H7A86_RS11085	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
H7A86_RS11100	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
H7A86_RS11105	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
H7A86_RS11110	ENOG4105BZ1	(ABC) transporter
H7A86_RS11125	ENOG4108EC8	DNA internalization-related competence protein ComEC
H7A86_RS11135	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H7A86_RS11140	ENOG4105D60	lipoprotein releasing system transmembrane protein
H7A86_RS11150	ENOG410681N	tpr repeat protein
H7A86_RS11175	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
H7A86_RS11185	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
H7A86_RS11200	ENOG4105CHC	glucokinase (EC 2.7.1.2)
H7A86_RS11210	ENOG4105C01	Dihydroxy-acid dehydratase
H7A86_RS11215	ENOG4108UHU	Aldolase
H7A86_RS11240	ENOG4105N7H	Cytochrome
H7A86_RS11310	ENOG4105BZU	Histidine kinase
H7A86_RS11315	ENOG4105BZM	domain protein
H7A86_RS11340	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
H7A86_RS11350	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H7A86_RS11385	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
H7A86_RS11390	ENOG4108Z6B	deaminase
H7A86_RS11395	ENOG4105KST	dependent repressor
H7A86_RS11400	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
H7A86_RS11425	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H7A86_RS11440	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
H7A86_RS11450	ENOG4105ESV	Glycosyl transferase, family 4
H7A86_RS11455	ENOG4105CFV	Tetratricopeptide repeat protein
H7A86_RS11470	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H7A86_RS11475	ENOG4105CAT	Cytidine monophosphate kinase
H7A86_RS11490	ENOG4105DWY	Agmatine deiminase
H7A86_RS11520	ENOG4105DRS	transport system, permease
H7A86_RS11525	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
H7A86_RS11555	ENOG4105K9H	YciI-like protein
H7A86_RS11560	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H7A86_RS11565	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H7A86_RS11570	ENOG4105FE9	pseudouridine synthase
H7A86_RS11590	ENOG4105CHM	Aminotransferase
H7A86_RS11595	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
H7A86_RS11600	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
H7A86_RS11605	ENOG41060IM	Heme exporter protein
H7A86_RS11615	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
H7A86_RS11620	ENOG4105DA4	cytochrome c-type biogenesis protein
H7A86_RS11630	ENOG4105KWW	Biogenesis protein
H7A86_RS11635	ENOG4108M1T	Cytochrome c-type biogenesis protein
H7A86_RS11640	ENOG4105DWV	Homoserine O-trans-acetylase
H7A86_RS11655	ENOG4108JJ8	(ABC) transporter
H7A86_RS11660	ENOG4108JJ9	ABC, transporter
H7A86_RS11665	ENOG4105C4M	(Ubiquinol oxidase) subunit I
H7A86_RS11670	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
H7A86_RS11725	ENOG4105CH7	arginosuccinase
H7A86_RS11740	ENOG4105CAS	nag kinase
H7A86_RS11750	ENOG4105CDH	Citrulline--aspartate ligase
H7A86_RS11755	ENOG4105DBV	ornithine carbamoyltransferase
H7A86_RS11765	ENOG4105C8N	cysteinyl-tRNA synthetase
H7A86_RS11770	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
H7A86_RS11790	ENOG4105CD3	dihydroorotase
H7A86_RS11805	ENOG4105CPD	ethanolamine ammonia-lyase
H7A86_RS11810	ENOG4107FQ9	ethanolamine ammonia-lyase
H7A86_RS11855	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H7A86_RS11865	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H7A86_RS11875	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H7A86_RS11880	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
H7A86_RS11885	ENOG4105BZU	Histidine kinase
H7A86_RS11900	ENOG4105ECY	inositol monophosphatase
H7A86_RS11905	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H7A86_RS11920	ENOG4105C5H	ABC transporter
H7A86_RS11925	ENOG4105C1J	atp-dependent rna helicase
H7A86_RS11930	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H7A86_RS11935	ENOG4105CNG	UPF0061 protein
H7A86_RS11945	ENOG4108RXX	maleylacetoacetate isomerase
H7A86_RS11950	ENOG4105VEQ	Cold shock protein
H7A86_RS11955	ENOG4108UPT	UPF0178 protein
H7A86_RS11960	ENOG4108VWS	Yaeq family
H7A86_RS11965	ENOG4105CBX	hi0933 family
H7A86_RS11980	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
H7A86_RS11985	ENOG4105CHR	reductase
H7A86_RS12005	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
H7A86_RS12010	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H7A86_RS12020	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H7A86_RS12025	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
H7A86_RS12040	ENOG4105E6M	Sulphatase-modifying factor protein
H7A86_RS12065	ENOG4105BZU	Histidine kinase
H7A86_RS12070	ENOG4108V3W	Chemotaxis protein, CheW
H7A86_RS12075	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS12080	ENOG4108VX5	3-methyladenine DNA glycosylase
H7A86_RS12085	ENOG4107QRT	dEAD DEAH box helicase
H7A86_RS12095	ENOG4105KB2	stringent starvation protein b
H7A86_RS12100	ENOG4107MKT	Stringent starvation protein a
H7A86_RS12105	ENOG4105EIX	cytochrome c1
H7A86_RS12110	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H7A86_RS12115	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H7A86_RS12120	ENOG4105E4C	Lytic transglycosylase catalytic
H7A86_RS12135	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H7A86_RS12145	ENOG4105C9A	Phoh family
H7A86_RS12155	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H7A86_RS12165	ENOG4108JU5	Magnesium and cobalt efflux protein
H7A86_RS12190	ENOG4105D38	putrescine abc transporter
H7A86_RS12195	ENOG4105F38	ABC transporter, permease
H7A86_RS12200	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H7A86_RS12220	ENOG4107RUE	extracellular solute-binding protein family 1
H7A86_RS12225	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H7A86_RS12240	ENOG4105CFQ	glutamine synthetase
H7A86_RS12245	ENOG4105CJP	fad dependent oxidoreductase
H7A86_RS12255	ENOG4105CSH	Transporter
H7A86_RS12265	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
H7A86_RS12290	ENOG4106BRA	Membrane
H7A86_RS12295	ENOG4105BZU	Histidine kinase
H7A86_RS12300	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
H7A86_RS12305	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H7A86_RS12315	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H7A86_RS12325	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
H7A86_RS12330	ENOG4105C7I	Dehydrogenase
H7A86_RS12340	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H7A86_RS12345	ENOG4105BZS	acriflavin resistance protein
H7A86_RS12350	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS12355	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H7A86_RS12360	ENOG4105DE4	1-phosphofructokinase
H7A86_RS12365	ENOG4105DM4	PTS System
H7A86_RS12405	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H7A86_RS12410	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H7A86_RS12415	ENOG4105VIE	preprotein translocase, subunit YajC
H7A86_RS12425	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
H7A86_RS12465	ENOG4105E08	Glycoside hydrolase, family 9
H7A86_RS12470	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
H7A86_RS12475	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
H7A86_RS12485	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H7A86_RS12490	ENOG4106H78	methyltransferase
H7A86_RS12495	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
H7A86_RS12505	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS12540	ENOG4107QTZ	amino acid
H7A86_RS12555	ENOG4105DC7	peptidase M24
H7A86_RS12565	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H7A86_RS12580	ENOG41080HI	glycine oxidase
H7A86_RS12585	ENOG4105CTU	Proline racemase
H7A86_RS12595	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H7A86_RS12605	ENOG4105CEN	a g-specific adenine glycosylase
H7A86_RS12615	ENOG4105CQZ	Histidine kinase
H7A86_RS12650	ENOG4105CSU	acyl-Coa dehydrogenase
H7A86_RS12660	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H7A86_RS12680	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
H7A86_RS12685	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H7A86_RS12690	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H7A86_RS12715	ENOG4108NQK	Catalyzes the transfer of a glucuronic acid (GlcA) residue from UDP-glucuronate to mannose-alpha-1,3-glucose-beta- 1,4-glucose-P-P-polyisoprenyl to form the lipid-linked tetrasaccharide GlcA-Man-Glc(2)-PP-Pol, with a glucuronic acid- beta-mannose linkage. Is involved in the biosynthesis of the exopolysaccharide xanthan, since it catalyzes the fourth glycosylation step in the assembly of the pentasaccharide-P-P- polyisoprenyl repeating unit of xanthan. Is unable to use the trisaccharide acceptor freed from the pyrophosphate lipid moiety. Does not show specificity for the lipidic portion of the acceptor. Shows diminished activity when tested with 6-O-acetyl-mannose- alpha-1,3-glucose-beta-1,4-glucose-P-P-polyisoprenyl, a
H7A86_RS12725	ENOG4107Y2G	Glycosyl transferase (Group 1
H7A86_RS12730	ENOG4107UFF	group 1 glycosyl transferase
H7A86_RS12750	ENOG4105D3Q	Sugar transferase
H7A86_RS12770	ENOG4105WJX	transcriptional regulator MERR family
H7A86_RS12780	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H7A86_RS12785	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H7A86_RS12800	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H7A86_RS12805	ENOG4105C22	threonyL-tRNA synthetase
H7A86_RS12810	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS12840	ENOG4105CG3	alpha amylase, catalytic region
H7A86_RS12850	ENOG4106E4H	Type IV secretory pathway VirB3 family protein
H7A86_RS12870	ENOG4105CMA	conjugation trbi family protein
H7A86_RS12950	ENOG4105EWT	decarboxylase family
H7A86_RS12955	ENOG4108KPZ	tonB-dependent Receptor
H7A86_RS12960	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
H7A86_RS12970	ENOG4105M2J	Glutaredoxin
H7A86_RS12975	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H7A86_RS12980	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H7A86_RS12985	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H7A86_RS12995	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H7A86_RS13015	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H7A86_RS13020	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
H7A86_RS13025	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H7A86_RS13030	ENOG4105CHV	Transcription elongation factor NusA
H7A86_RS13035	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
H7A86_RS13045	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H7A86_RS13050	ENOG4105C8S	subunit m
H7A86_RS13070	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H7A86_RS13080	ENOG4107R0R	NADH dehydrogenase subunit g
H7A86_RS13085	ENOG4107QIZ	NADH dehydrogenase
H7A86_RS13090	ENOG4105GKE	subunit e
H7A86_RS13100	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H7A86_RS13110	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H7A86_RS13125	ENOG4105CP7	Triose-phosphate isomerase
H7A86_RS13130	ENOG4105EMU	Dehydrogenase
H7A86_RS13145	ENOG4105BZU	Histidine kinase
H7A86_RS13160	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
H7A86_RS13210	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H7A86_RS13215	ENOG4105C5I	Dehydrogenase
H7A86_RS13220	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
H7A86_RS13230	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
H7A86_RS13240	ENOG4105DJ4	phosphatidylserine decarboxylase
H7A86_RS13250	ENOG4105D7A	ATP-binding protein
H7A86_RS13260	ENOG4107VIJ	nudix hydrolase
H7A86_RS13275	ENOG4108RRZ	Transcription elongation factor GreB
H7A86_RS13285	ENOG41067QW	Transcriptional regulator
H7A86_RS13295	ENOG4106A2Z	transcriptional regulator antitoxin, MazE
H7A86_RS13345	ENOG4105DHP	deoxycytidine triphosphate deaminase
H7A86_RS13350	ENOG4105D1F	ATP-binding protein
H7A86_RS13365	ENOG4105C9K	Endothelin-converting enzyme 1
H7A86_RS13370	ENOG4105C9K	Endothelin-converting enzyme 1
H7A86_RS13390	ENOG4105DC8	reductase
H7A86_RS13395	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H7A86_RS13410	ENOG4108YZY	peptidylprolyl cis-trans isomerase
H7A86_RS13415	ENOG4105K4H	Nlp p60 protein
H7A86_RS13420	ENOG4105K4H	Nlp p60 protein
H7A86_RS13440	ENOG4105CK2	sodium dicarboxylate symporter
H7A86_RS13445	ENOG4105G6Z	alkaline phosphatase
H7A86_RS13450	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H7A86_RS13455	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H7A86_RS13460	ENOG4105CTB	Polyprenyl synthetase
H7A86_RS13475	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
H7A86_RS13480	ENOG4105N42	UPF0307 protein
H7A86_RS13485	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
H7A86_RS13495	ENOG4105QD6	exported protein
H7A86_RS13500	ENOG4105C03	ribonuclease
H7A86_RS13505	ENOG4108Z03	MAF-like protein
H7A86_RS13510	ENOG4105MPN	Membrane
H7A86_RS13520	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
H7A86_RS13540	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H7A86_RS13555	ENOG4105C8T	Leucyl-tRNA synthetase
H7A86_RS13565	ENOG4107QR8	Thioredoxin
H7A86_RS13615	ENOG4105BZ1	(ABC) transporter
H7A86_RS13630	ENOG4105FQP	Beta-lactamase
H7A86_RS13635	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
H7A86_RS13655	ENOG4105FE9	pseudouridine synthase
H7A86_RS13660	ENOG4105BZU	Histidine kinase
H7A86_RS13670	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H7A86_RS13750	ENOG4105UGU	tonB-dependent Receptor
H7A86_RS13760	ENOG4105CPC	Aldo Keto reductase
H7A86_RS13765	ENOG4105F27	Major Facilitator
H7A86_RS13770	ENOG4105EJC	lysr family transcriptional regulator
H7A86_RS13780	ENOG4105CF7	AraC family transcriptional regulator
H7A86_RS13790	ENOG4105EQ2	LysR family Transcriptional regulator
H7A86_RS13800	ENOG4108JGH	Tetr family transcriptional regulator
H7A86_RS13805	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H7A86_RS13810	ENOG4105BZS	acriflavin resistance protein
H7A86_RS13815	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H7A86_RS13825	ENOG4105MYN	Zinc uptake regulation protein
H7A86_RS13830	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H7A86_RS13855	ENOG4105CT7	inner membrane cred family protein
H7A86_RS13875	ENOG4105EB3	Histidine kinase
H7A86_RS13880	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
H7A86_RS13885	ENOG4105D6S	protein involved in catabolism of external DNA
H7A86_RS13895	ENOG4108JA2	transcriptioN-repair coupling factor
H7A86_RS13905	ENOG4105CBS	Chea signal transduction histidine kinase
H7A86_RS13915	ENOG4108V3W	Chemotaxis protein, CheW
H7A86_RS13920	ENOG4105BZU	Histidine kinase
H7A86_RS13925	ENOG4105BZU	Histidine kinase
H7A86_RS13930	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H7A86_RS13935	ENOG4107RZC	phospholipase d
H7A86_RS13940	ENOG4105C9K	Endothelin-converting enzyme 1
H7A86_RS13950	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H7A86_RS13955	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
H7A86_RS13960	ENOG4105EUB	pirin domain protein
H7A86_RS13970	ENOG4105EUB	pirin domain protein
H7A86_RS13975	ENOG4105D22	carbon starvation protein
H7A86_RS13980	ENOG4105VCD	cytoplasmic protein
H7A86_RS13985	ENOG4107YBY	Hydrolase
H7A86_RS14015	ENOG4107XAN	XdhC and CoxI family
H7A86_RS14020	ENOG4105C7W	Xanthine dehydrogenase
H7A86_RS14025	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
H7A86_RS14030	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
H7A86_RS14045	ENOG4108UUM	single-stranded DNA-binding protein
H7A86_RS14050	ENOG4105EAH	synthase
H7A86_RS14060	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
H7A86_RS14075	ENOG4105CFH	Aspartokinase
H7A86_RS14085	ENOG4105JAB	phenazine biosynthesis protein, phzf family
H7A86_RS14095	ENOG4108Z9K	Osmotically inducible protein
H7A86_RS14105	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
H7A86_RS14110	ENOG4108UJU	UPF0301 protein
H7A86_RS14115	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H7A86_RS14135	ENOG4105CZX	twitching motility protein
H7A86_RS14140	ENOG4105CZX	twitching motility protein
H7A86_RS14145	ENOG4105DFA	alanine racemase domain protein
H7A86_RS14150	ENOG4105II7	pyrroline-5-carboxylate reductase
H7A86_RS14160	ENOG4108K5P	(LipO)protein
H7A86_RS14180	ENOG4108Z0Z	intracellular protease Pfpi family
H7A86_RS14200	ENOG4105C3K	feS assembly ATPase SufC
H7A86_RS14205	ENOG4105JRK	feS assembly protein SufD
H7A86_RS14210	ENOG4105C9B	Cysteine desulfurase
H7A86_RS14220	ENOG4105VQD	rieske 2fe-2S domain-containing protein
H7A86_RS14225	ENOG4108ESX	Receptor
H7A86_RS14230	ENOG4107E2E	PKHD-type hydroxylase
H7A86_RS14255	ENOG4105CJ2	(LipO)protein
H7A86_RS14270	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
H7A86_RS14275	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H7A86_RS14285	ENOG4105EHM	Aminoglycoside phosphotransferase
H7A86_RS14290	ENOG4108S0S	Nucleotidyl transferase
H7A86_RS14300	ENOG4105C02	permease
H7A86_RS14320	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H7A86_RS14340	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H7A86_RS14350	ENOG4105C2X	Arabinose 5-phosphate isomerase
H7A86_RS14355	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
H7A86_RS14365	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
H7A86_RS14370	ENOG4108IUZ	ABC transporter
H7A86_RS14375	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H7A86_RS14380	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
H7A86_RS14385	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
H7A86_RS14405	ENOG41080Z8	PHOSPHOCARRIER protein
H7A86_RS14410	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H7A86_RS14415	ENOG4105CJW	magnesium transporter
H7A86_RS14420	ENOG4107UWA	esterase
H7A86_RS14425	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
H7A86_RS14430	ENOG4105C4M	(Ubiquinol oxidase) subunit I
H7A86_RS14435	ENOG4105C85	amino acid
H7A86_RS14440	ENOG4108NFF	pectate lyase
H7A86_RS14455	ENOG4105CUB	amino acid
H7A86_RS14460	ENOG4108MHS	Lysyl endopeptidase
H7A86_RS14475	ENOG4105QV4	Tryptophan halogenase
H7A86_RS14500	ENOG4108Z4X	TRANSCRIPTIONal
H7A86_RS14510	ENOG4106032	Glutathionylspermidine synthase
H7A86_RS14535	ENOG4108P9J	Phage shock protein A
H7A86_RS14545	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
H7A86_RS14550	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
H7A86_RS14555	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
H7A86_RS14560	ENOG4105D49	3-dehydroquinate synthase
H7A86_RS14570	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
H7A86_RS14640	ENOG4108JUA	Transcriptional regulator
H7A86_RS14645	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H7A86_RS14650	ENOG4105BZU	Histidine kinase
H7A86_RS14655	ENOG4105BZU	Histidine kinase
H7A86_RS14660	ENOG4108YYC	ycei family
H7A86_RS14665	ENOG4105CPW	cytochrome b561
H7A86_RS14680	ENOG4105EJQ	L-serine dehydratase
H7A86_RS14690	ENOG4105CFH	Aspartokinase
H7A86_RS14695	ENOG4105C28	cystathionine
H7A86_RS14700	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
H7A86_RS14705	ENOG4105DR5	peptidase
H7A86_RS14710	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
H7A86_RS14715	ENOG4108UT2	hemolysin iii
H7A86_RS14720	ENOG41066T0	asmA family
H7A86_RS14725	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H7A86_RS14735	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
H7A86_RS14740	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
H7A86_RS14750	ENOG4105D05	Receptor
H7A86_RS14755	ENOG4108IG5	Transcriptional regulator
H7A86_RS14765	ENOG4107QPN	acyl-Coa dehydrogenase
H7A86_RS14800	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H7A86_RS14805	ENOG4105KK4	UPF0060 membrane protein
H7A86_RS14815	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
H7A86_RS14820	ENOG4107RK2	ADP-ribose diphosphatase NudE
H7A86_RS14830	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H7A86_RS14835	ENOG4105CHC	glucokinase (EC 2.7.1.2)
H7A86_RS14850	ENOG4105VRS	hydrolase family 18
H7A86_RS14855	ENOG4105E2D	ec 3.2.1.52
H7A86_RS14875	ENOG4105CWX	Alpha-1,2-mannosidase
H7A86_RS14900	ENOG4106N3A	copper homeostasis protein cutc
H7A86_RS14910	ENOG4105D9U	N-acetyltransferase
H7A86_RS14920	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H7A86_RS14930	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS14940	ENOG4105M3Z	response regulator
H7A86_RS14945	ENOG4108UNF	response regulator
H7A86_RS14950	ENOG4105D7Z	glutathione synthase
H7A86_RS14960	ENOG41065RQ	ADP-ribosylation crystallin J1
H7A86_RS14965	ENOG41072GX	Peptidase M22 Glycoprotease
H7A86_RS14970	ENOG4105DVT	helicase
H7A86_RS14980	ENOG4105BZ4	penicillin-binding protein
H7A86_RS14995	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H7A86_RS15005	ENOG410698T	Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity)
H7A86_RS15015	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
H7A86_RS15020	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
H7A86_RS15035	ENOG4105CHC	glucokinase (EC 2.7.1.2)
H7A86_RS15050	ENOG4105CQ7	ATP-dependent helicase
H7A86_RS15060	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H7A86_RS15130	ENOG4107S5I	aldo keto reductase
H7A86_RS15135	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
H7A86_RS15145	ENOG4105KCK	Peptidoglycan-associated lipoprotein
H7A86_RS15150	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
H7A86_RS15165	ENOG4105E02	MotA TolQ exbB proton channel
H7A86_RS15170	ENOG4107YD3	Thioesterase
H7A86_RS15180	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H7A86_RS15225	ENOG4108ISG	Major Facilitator
H7A86_RS15235	ENOG4105HSS	phospholipase C
H7A86_RS15245	ENOG4105ETT	transcriptional Regulator, LysR family
H7A86_RS15250	ENOG4105C5H	ABC transporter
H7A86_RS15255	ENOG4107RNH	Outer membrane receptor FepA
H7A86_RS15265	ENOG4107RNH	Outer membrane receptor FepA
H7A86_RS15270	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS15280	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
H7A86_RS15290	ENOG4105GAV	receptor
H7A86_RS15305	ENOG4105C6X	Major Facilitator
H7A86_RS15310	ENOG4105DBM	Siderophore biosynthesis protein
H7A86_RS15315	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
H7A86_RS15330	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
H7A86_RS15340	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS15355	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H7A86_RS15360	ENOG4105E2Y	ABC, transporter
H7A86_RS15365	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
H7A86_RS15370	ENOG4105GVF	(ABC) transporter
H7A86_RS15375	ENOG4105CPC	Aldo Keto reductase
H7A86_RS15385	ENOG4107ZSV	Receptor
H7A86_RS15390	ENOG41082IR	Excinuclease ABC C subunit domain protein
H7A86_RS15430	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS15435	ENOG4108K4C	ec 3.1.3.12
H7A86_RS15440	ENOG4105BZP	glycoside hydrolase 15-related
H7A86_RS15445	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
H7A86_RS15450	ENOG4105DZG	Dehydrogenase
H7A86_RS15455	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS15460	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H7A86_RS15465	ENOG4105C34	Pseudouridine synthase
H7A86_RS15470	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7A86_RS15480	ENOG4105C4K	Nad synthetase
H7A86_RS15490	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
H7A86_RS15495	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
H7A86_RS15500	ENOG4107TUY	Histidine kinase
H7A86_RS15505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H7A86_RS15510	ENOG4107QHF	type ii secretion system protein e
H7A86_RS15520	ENOG4105D7Q	type ii secretion system
H7A86_RS15525	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
H7A86_RS15530	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H7A86_RS15540	ENOG4105BZU	Histidine kinase
H7A86_RS15545	ENOG4105ETX	regulatoR
H7A86_RS15555	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
H7A86_RS15580	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS15585	ENOG4108V1U	phospholipid-binding protein
H7A86_RS15595	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H7A86_RS15600	ENOG4107QPK	)-transporter
H7A86_RS15625	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H7A86_RS15650	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H7A86_RS15660	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS15685	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H7A86_RS15700	ENOG4105CD8	aminopeptidase N
H7A86_RS15705	ENOG4105BZS	acriflavin resistance protein
H7A86_RS15710	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H7A86_RS15715	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
H7A86_RS15725	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
H7A86_RS15730	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
H7A86_RS15755	ENOG4105BZU	Histidine kinase
H7A86_RS15765	ENOG4107R11	Transcriptional regulator
H7A86_RS15770	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H7A86_RS15780	ENOG4108UVJ	appr-1-p processing domain protein
H7A86_RS15785	ENOG4107R1Y	fructose-bisphosphate aldolase
H7A86_RS15790	ENOG4105CA9	Pyruvate kinase
H7A86_RS15820	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H7A86_RS15835	ENOG4105EIF	outer membrane protein W
H7A86_RS15845	ENOG4107S76	domain protein
H7A86_RS15850	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
H7A86_RS15855	ENOG4105E0C	molybdate abc transporter
H7A86_RS15860	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
H7A86_RS15900	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
H7A86_RS15905	ENOG4105DR5	peptidase
H7A86_RS15910	ENOG4105CHR	reductase
H7A86_RS15915	ENOG4105CBN	LysR family transcriptional regulator
H7A86_RS15920	ENOG4105CNM	Receptor
H7A86_RS15925	ENOG4105CV1	Transketolase (EC 2.2.1.1)
H7A86_RS15930	ENOG4105CK2	sodium dicarboxylate symporter
H7A86_RS15960	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H7A86_RS15965	ENOG4105E4G	Type IV pilus
H7A86_RS15990	ENOG4108JQC	penicillin-binding protein 1A
H7A86_RS16010	ENOG4105DU0	nucleoside hydrolase
H7A86_RS16015	ENOG4105CB5	ATP-dependent DNA helicase recG
H7A86_RS16020	ENOG4105KME	endoribonuclease L-psp
H7A86_RS16025	ENOG4105CTX	dehydratase
H7A86_RS16030	ENOG4105EPF	Outer membrane porin
H7A86_RS16040	ENOG4105DJB	Major Facilitator Superfamily
H7A86_RS16060	ENOG4107RSM	transcriptional regulator
H7A86_RS16065	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H7A86_RS16075	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H7A86_RS16080	ENOG4105DSJ	YicC domain protein
H7A86_RS16085	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
H7A86_RS16095	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H7A86_RS16100	ENOG4105CSA	Coproporphyrinogen iii oxidase
H7A86_RS16115	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
H7A86_RS16125	ENOG4107RAQ	aminopeptidase
H7A86_RS16140	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
H7A86_RS16150	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H7A86_RS16170	ENOG41063JG	Transcriptional regulator
H7A86_RS16175	ENOG4105VCQ	rubredoxin
H7A86_RS16180	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
H7A86_RS16190	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H7A86_RS16195	ENOG41061ZR	Transcriptional regulator
H7A86_RS16200	ENOG41090JD	Blue (Type 1) copper domain protein
H7A86_RS16205	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H7A86_RS16235	ENOG4105C8Y	Acetylornithine aminotransferase
H7A86_RS16240	ENOG4105EYW	Ion transport protein
H7A86_RS16265	ENOG410841Q	phosphoesterase PA-phosphatase related protein
H7A86_RS16270	ENOG4105FFC	UPF0187 protein
H7A86_RS16280	ENOG4105DFU	Cell wall formation (By similarity)
H7A86_RS16285	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H7A86_RS16305	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
H7A86_RS16315	ENOG4105F0N	pyrophosphate phospho-hydrolase
H7A86_RS16325	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS16330	ENOG4105ECQ	AraC Family Transcriptional Regulator
H7A86_RS16335	ENOG4108M3R	transcriptional activator CadC
H7A86_RS16345	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
H7A86_RS16355	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
H7A86_RS16375	ENOG4105C7B	Threonine dehydratase
H7A86_RS16380	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H7A86_RS16385	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H7A86_RS16390	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H7A86_RS16395	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H7A86_RS16400	ENOG4108MP6	LysR family Transcriptional regulator
H7A86_RS16405	ENOG4105BZU	Histidine kinase
H7A86_RS16415	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H7A86_RS16420	ENOG4105DFG	type I secretion outer membrane protein
H7A86_RS16425	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
H7A86_RS16430	ENOG4105D1S	lipid A biosynthesis
H7A86_RS16455	ENOG4105C6K	Malic enzyme
H7A86_RS16485	ENOG4105CPC	Aldo Keto reductase
H7A86_RS16490	ENOG4105WH1	Two component transcriptional regulator luxr family
H7A86_RS16495	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
H7A86_RS16500	ENOG4105DHQ	Histidine kinase
H7A86_RS16515	ENOG4105D4T	Citrate transporter
H7A86_RS16520	ENOG4105CHR	reductase
H7A86_RS16525	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS16540	ENOG4107QW3	Sucrose phosphorylase
H7A86_RS16580	ENOG4105CNM	Receptor
H7A86_RS16605	ENOG41069H0	dihydroorotase EC 3.5.2.3
H7A86_RS16610	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H7A86_RS16635	ENOG4108RMV	DegV Family
H7A86_RS16645	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
H7A86_RS16650	ENOG4107YIM	Involved in the transcription termination process (By similarity)
H7A86_RS16660	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H7A86_RS16675	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H7A86_RS16690	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H7A86_RS16700	ENOG4105C5H	ABC transporter
H7A86_RS16705	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H7A86_RS16770	ENOG4106S9K	Transcriptional regulator
H7A86_RS16780	ENOG4105GVR	general secretion pathway protein D
H7A86_RS16790	ENOG410678M	general secretion pathway protein M
H7A86_RS16795	ENOG41090VX	general secretion pathway protein L
H7A86_RS16800	ENOG4105UV2	general secretion pathway protein K
H7A86_RS16805	ENOG41069G9	General secretion pathway protein J
H7A86_RS16815	ENOG4105WMT	general secretion pathway protein h
H7A86_RS16825	ENOG4105D7Q	type ii secretion system
H7A86_RS16830	ENOG4107QHF	type ii secretion system protein e
H7A86_RS16835	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
H7A86_RS16840	ENOG4105EUR	Domain-Containing protein
H7A86_RS16845	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
H7A86_RS16850	ENOG4105EUR	Domain-Containing protein
H7A86_RS16855	ENOG4108ETH	Formylglycinamide ribotide synthetase
H7A86_RS16860	ENOG4105T95	Thiol disulfide interChange protein
H7A86_RS16865	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H7A86_RS16875	ENOG4108K5H	permease YjgP YjgQ family protein
H7A86_RS16920	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H7A86_RS16950	ENOG4105DHJ	ABC, transporter
H7A86_RS16955	ENOG4108SNX	Mammalian cell entry related domain protein
H7A86_RS16970	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H7A86_RS16985	ENOG4107QP7	CoA-transferase subunit A
H7A86_RS16990	ENOG4107QKV	phosphomannomutase
H7A86_RS16995	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
H7A86_RS17000	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
H7A86_RS17005	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H7A86_RS17020	ENOG4105BZJ	Electron transfer flavoprotein
H7A86_RS17025	ENOG4105C10	Electron transfer flavoprotein
H7A86_RS17030	ENOG4105C28	cystathionine
H7A86_RS17085	ENOG4105CZX	twitching motility protein
H7A86_RS17090	ENOG4108RXX	maleylacetoacetate isomerase
H7A86_RS17100	ENOG4105C1J	atp-dependent rna helicase
H7A86_RS17110	ENOG4105D05	Receptor
H7A86_RS17115	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
H7A86_RS17125	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
H7A86_RS17140	ENOG4105NIV	Esterase
H7A86_RS17145	ENOG4107RNH	Outer membrane receptor FepA
H7A86_RS17150	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H7A86_RS17155	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H7A86_RS17170	ENOG4105DGW	oligopeptidase A
H7A86_RS17205	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H7A86_RS17210	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H7A86_RS17215	ENOG4105C19	ABC transporter
H7A86_RS17220	ENOG4107RBB	ABC transporter, permease
H7A86_RS17235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H7A86_RS17255	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H7A86_RS17290	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H7A86_RS17295	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H7A86_RS17300	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H7A86_RS17305	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
H7A86_RS17325	ENOG4107QN2	dihydrolipoyl dehydrogenase
H7A86_RS17335	ENOG4107QSN	dihydrolipoamide acetyltransferase
H7A86_RS17365	ENOG4105D01	(LipO)protein
H7A86_RS17370	ENOG4108UMI	ABC transporter, permease
H7A86_RS17375	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H7A86_RS17380	ENOG4105DJP	Membrane
H7A86_RS17385	ENOG4108VPT	UPF0234 protein
H7A86_RS17395	ENOG4105BZU	Histidine kinase
H7A86_RS17410	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
H7A86_RS17415	ENOG4105I08	Pseudouridine synthase
H7A86_RS17440	ENOG4105I8F	Histidine kinase
H7A86_RS17460	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H7A86_RS17465	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H7A86_RS17470	ENOG4105EW9	transcriptional regulator AsnC family
H7A86_RS17485	ENOG4107RD7	Flagellar Motor Protein, MotA
H7A86_RS17490	ENOG4105ER2	Ompa motb domain protein
H7A86_RS17515	ENOG4105E3A	(ABC) transporter
H7A86_RS17520	ENOG4105DA5	(ABC) transporter
H7A86_RS17525	ENOG4105EEQ	Na H antiporter
H7A86_RS17540	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
H7A86_RS17550	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
H7A86_RS17560	ENOG4105CC0	LysR family Transcriptional regulator
H7A86_RS17570	ENOG4105CPC	Aldo Keto reductase
H7A86_RS17580	ENOG4105C9K	Endothelin-converting enzyme 1
H7A86_RS17595	ENOG4107QTZ	amino acid
H7A86_RS17605	ENOG4108VAC	response regulator
H7A86_RS17610	ENOG4105C2F	Histidine kinase
H7A86_RS17625	ENOG4108Z9Z	response to DNA damage stimulus
H7A86_RS17630	ENOG4105WEF	catalase
H7A86_RS17640	ENOG4105BZU	Histidine kinase
H7A86_RS17655	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H7A86_RS17665	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H7A86_RS17675	ENOG4105E2A	Dehydrogenase
H7A86_RS17735	ENOG4105DA5	(ABC) transporter
H7A86_RS17755	ENOG4105C8Q	Methyl-accepting chemotaxis
H7A86_RS17790	ENOG4105CHH	sulfate transporter
H7A86_RS17795	ENOG4105CMQ	Chloride channel
H7A86_RS17815	ENOG4108IND	Tetr family transcriptional regulator
H7A86_RS17825	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H7A86_RS17830	ENOG4108JGH	Tetr family transcriptional regulator
H7A86_RS17860	ENOG4105K56	Transcriptional regulator
H7A86_RS17905	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H7A86_RS17910	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
H7A86_RS17920	ENOG4108Z7F	N-acetyltransferase
H7A86_RS17925	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
H7A86_RS17960	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H7A86_RS17965	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H7A86_RS17970	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H7A86_RS17975	ENOG4108WZM	domain protein
H7A86_RS17980	ENOG4105C79	DNA protecting protein DprA
H7A86_RS18000	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H7A86_RS18020	ENOG4107ZQV	short-chain dehydrogenase reductase
H7A86_RS18030	ENOG4105D07	Signal peptide peptidase, SppA
H7A86_RS18035	ENOG4107QI1	Mate efflux family protein
H7A86_RS18050	ENOG4105C25	Primosomal protein n'
H7A86_RS18055	ENOG4108TGY	Glutathione S-transferase
H7A86_RS18075	ENOG4105EN6	Membrane
H7A86_RS18080	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H7A86_RS18090	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
H7A86_RS18095	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
H7A86_RS18100	ENOG4105CAK	Cell division ATP-binding protein ftsE
H7A86_RS18115	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
H7A86_RS18120	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
H7A86_RS18125	ENOG4105E9K	Isocitrate dehydrogenase
H7A86_RS18140	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
H7A86_RS18145	ENOG4105CH2	amidohydrolase
H7A86_RS18155	ENOG4105BZS	acriflavin resistance protein
H7A86_RS18165	ENOG4105E32	cytoplasmic protein
H7A86_RS18205	ENOG4108UQS	dipeptidase
H7A86_RS18220	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
H7A86_RS18230	ENOG4105DTQ	mandelate racemase muconate lactonizing
H7A86_RS18240	ENOG4105D5Q	Arginine ornithine antiporter
H7A86_RS18260	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
H7A86_RS18265	ENOG4107ZVW	dihydroneopterin aldolase
H7A86_RS18280	ENOG4105KTH	gatB Yqey
H7A86_RS18285	ENOG4107S2Z	UPF0761 membrane protein
H7A86_RS18290	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H7A86_RS18295	ENOG4105DHU	Bile acid
H7A86_RS18305	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
H7A86_RS18330	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
H7A86_RS18335	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
H7A86_RS18350	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
H7A86_RS18360	ENOG4105C26	Dehydrogenase
H7A86_RS18390	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
H7A86_RS18395	ENOG4105DR5	peptidase
H7A86_RS18400	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
H7A86_RS18410	ENOG4105EYM	Major Facilitator superfamily
H7A86_RS18415	ENOG4105CGK	Exodeoxyribonuclease III
H7A86_RS18430	ENOG4107QJE	Chromosome Partitioning Protein
H7A86_RS18435	ENOG4105FA0	parb-like partition protein
H7A86_RS18455	ENOG4105CKK	Glycosyl transferase, family 2
H7A86_RS18470	ENOG4107QKV	phosphomannomutase
H7A86_RS18480	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H7A86_RS18490	ENOG4105C75	arginyL-tRNA synthetase
H7A86_RS18505	ENOG4105EMU	Dehydrogenase
H7A86_RS18510	ENOG4105EXC	Acyl-transferase
H7A86_RS18520	ENOG4105CEY	Amp-dependent synthetase and ligase
H7A86_RS18530	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
H7A86_RS18535	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
H7A86_RS18555	ENOG4108YZA	Nitrogen regulatory protein pii
H7A86_RS18560	ENOG4105W0Z	cytoplasmic protein
H7A86_RS18565	ENOG4105C0P	Mg chelatase subunit ChlI
H7A86_RS18580	ENOG41066DG	(EAL) domain protein
H7A86_RS18595	ENOG4105EJ2	Transcriptional regulator
H7A86_RS18635	ENOG4105ECP	epimerase
H7A86_RS18640	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H7A86_RS18645	ENOG4105DHQ	Histidine kinase
H7A86_RS18665	ENOG4105C0H	protease
H7A86_RS18685	ENOG4105C02	permease
H7A86_RS18690	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
H7A86_RS18695	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H7A86_RS18715	ENOG4108S01	response regulator
H7A86_RS18720	ENOG4108ZGX	Histidine kinase
H7A86_RS18725	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H7A86_RS18730	ENOG4105C19	ABC transporter
H7A86_RS18755	ENOG4105FDR	Membrane
H7A86_RS18775	ENOG4105C31	Tryptophanyl-tRNA synthetase
H7A86_RS18780	ENOG4105VDW	Csbd family
H7A86_RS18840	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
H7A86_RS18865	ENOG4105EB3	Histidine kinase
H7A86_RS18870	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H7A86_RS18880	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H7A86_RS18895	ENOG4105CH6	catalase
H7A86_RS18905	ENOG4105DVT	helicase
H7A86_RS18935	ENOG4105D52	delta-aminolevulinic acid dehydratase
H7A86_RS18995	ENOG4105CYM	Glutathione S-transferase
H7A86_RS19015	ENOG4105QV4	Tryptophan halogenase
H7A86_RS19030	ENOG4108IUW	ABC transporter
H7A86_RS19040	ENOG4105VZ8	Transcriptional regulator
H7A86_RS19135	ENOG4105DA5	(ABC) transporter
H7A86_RS19140	ENOG4105E3A	(ABC) transporter
H7A86_RS19145	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H7A86_RS19170	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H7A86_RS19175	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H7A86_RS19185	ENOG4105CD5	CoA-binding domain protein
H7A86_RS19205	ENOG4105CJW	magnesium transporter
H7A86_RS19210	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
H7A86_RS19215	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H7A86_RS19220	ENOG4105BZP	glycoside hydrolase 15-related
H7A86_RS19240	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H7A86_RS19265	ENOG4105C2D	reductase
H7A86_RS19295	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H7A86_RS19300	ENOG4105E9Q	Acyl-transferase
H7A86_RS19310	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H7A86_RS19345	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
H7A86_RS19350	ENOG4105C2M	dna polymerase I
H7A86_RS19385	ENOG4105C4R	Atp-dependent dna helicase
H7A86_RS19395	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H7A86_RS19405	ENOG4105JSC	dimethylmenaquinone methyltransferase
H7A86_RS19415	ENOG4105KHM	amidohydrolase 2
H7A86_RS19435	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H7A86_RS19460	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
H7A86_RS19470	ENOG4105DGI	Alkaline phosphatase
H7A86_RS19510	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
H7A86_RS19520	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
H7A86_RS19530	ENOG4107QN1	sodium solute
H7A86_RS19545	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H7A86_RS19570	ENOG4105DSG	hydrolase family 43
H7A86_RS19590	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
H7A86_RS19595	ENOG4105ERH	Fumarylacetoacetate hydrolase
H7A86_RS19600	ENOG4105DIA	mandelate racemase muconate lactonizing
H7A86_RS19605	ENOG4105QJH	Domain of unknown function (DUF718)
H7A86_RS19610	ENOG4105EDR	glucose galactose transporter
H7A86_RS19615	ENOG4108K2P	TRANSCRIPTIONal
H7A86_RS19620	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
H7A86_RS19630	ENOG4105BZU	Histidine kinase
H7A86_RS19635	ENOG4105E2V	Glycosyltransferase 36
H7A86_RS19640	ENOG4105CT4	transporter
H7A86_RS19645	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
H7A86_RS19670	ENOG4105MA0	exported protein
H7A86_RS19675	ENOG4105CFU	surface antigen
H7A86_RS19680	ENOG4105D05	Receptor
H7A86_RS19685	ENOG4107RDJ	Sulfotransferase
H7A86_RS19700	ENOG4107QHF	type ii secretion system protein e
H7A86_RS19705	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H7A86_RS19715	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H7A86_RS19720	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
H7A86_RS19735	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
H7A86_RS19750	ENOG4105DH7	May be involved in recombination (By similarity)
H7A86_RS19755	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
H7A86_RS19760	ENOG4105C93	Xylose Isomerase
H7A86_RS19765	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS19770	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
H7A86_RS19780	ENOG4105CXK	mandelate racemase muconate lactonizing
H7A86_RS19795	ENOG4105DEI	Mannitol dehydrogenase
H7A86_RS19815	ENOG4105C5I	Dehydrogenase
H7A86_RS19850	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
H7A86_RS19855	ENOG4105CNT	hydrolase family 2
H7A86_RS19860	ENOG4105D2H	Uronic isomerase
H7A86_RS19880	ENOG4105CT4	transporter
H7A86_RS19885	ENOG4105DT9	hydrolase family 43
H7A86_RS19910	ENOG4105E55	glycerol-3-phosphate acyltransferase
H7A86_RS19920	ENOG4105ETE	Transcriptional regulator (LacI family
H7A86_RS19935	ENOG4105QV4	Tryptophan halogenase
H7A86_RS19940	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
H7A86_RS19945	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
H7A86_RS19950	ENOG4108YXG	UPF0502 protein
H7A86_RS19965	ENOG4105KNA	-acetyltransferase
H7A86_RS19970	ENOG4105C4R	Atp-dependent dna helicase
H7A86_RS19975	ENOG4107104	thymidine kinase
H7A86_RS19980	ENOG4105BZU	Histidine kinase
H7A86_RS19985	ENOG4105DJ9	glucan biosynthesis protein
H7A86_RS19995	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H7A86_RS20025	ENOG4105DKK	Benzoate
H7A86_RS20060	ENOG4105DSB	aldose 1-epimerase
H7A86_RS20075	ENOG4105EJ9	Membrane
H7A86_RS20080	ENOG4105E0K	tonB-dependent siderophore receptor
H7A86_RS20100	ENOG4105EUJ	GTP cyclohydrolase i
H7A86_RS20110	ENOG4105ZQC	membrane protein AaeX
H7A86_RS20115	ENOG4105Y49	secretion protein, HlyD family
H7A86_RS20125	ENOG4105DR8	Membrane
H7A86_RS20130	ENOG4105CSH	Transporter
H7A86_RS20145	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H7A86_RS20260	ENOG4107QYX	exodeoxyribonuclease v alpha
H7A86_RS20265	ENOG4107QKA	exodeoxyribonuclease V beta
H7A86_RS20270	ENOG4105DSY	exodeoxyribonuclease V, gamma
H7A86_RS20295	ENOG410870W	N-acetyltransferase
H7A86_RS20305	ENOG4105DHJ	ABC, transporter
H7A86_RS20310	ENOG4105CY3	ABC transporter, permease
H7A86_RS20315	ENOG4107PE3	Mammalian cell entry related domain protein
H7A86_RS20330	ENOG410903C	(LipO)protein
H7A86_RS20340	ENOG4108V06	Glutathione peroxidase
H7A86_RS20350	ENOG4107QSV	RmuC domain protein
H7A86_RS20355	ENOG4105CIS	alcohol dehydrogenase
H7A86_RS20370	ENOG4108TGY	Glutathione S-transferase
H7A86_RS20380	ENOG4105CUB	amino acid
H7A86_RS20385	ENOG4105CWX	Alpha-1,2-mannosidase
H7A86_RS20395	ENOG4105BZU	Histidine kinase
H7A86_RS20400	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
H7A86_RS20405	ENOG4105BZW	Glycerate kinase
H7A86_RS20410	ENOG4105CSP	Major Facilitator Superfamily
H7A86_RS20430	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H7A86_RS20450	ENOG4105DR4	Methyltransferase
H7A86_RS20455	ENOG4105DU1	integral membrane protein, terc
H7A86_RS20465	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
H7A86_RS20490	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
H7A86_RS20575	ENOG4106H6R	UPF0380 protein
H7A86_RS20685	ENOG4105CMA	conjugation trbi family protein