locus-tag	class	description
KHA79_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHA79_RS00020	COG0187	DNA topoisomerase II activity
KHA79_RS00025	COG1266	CAAX protease self-immunity
KHA79_RS00030	COG0501	Belongs to the peptidase M48B family
KHA79_RS00065	COG0583	DNA-binding transcription factor activity
KHA79_RS00085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHA79_RS00125	COG4772	TonB-dependent receptor
KHA79_RS00135	COG3284	Transcriptional regulator
KHA79_RS00145	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_RS00180	COG1304	FMN binding
KHA79_RS00185	COG2186	Transcriptional regulator
KHA79_RS00245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHA79_RS00265	COG4771	TonB-dependent receptor
KHA79_RS00315	COG3186	Phenylalanine-4-hydroxylase
KHA79_RS00320	COG1522	sequence-specific DNA binding
KHA79_RS00325	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHA79_RS00340	COG0671	phosphoesterase, PA-phosphatase related
KHA79_RS00350	COG0861	Integral membrane protein TerC family
KHA79_RS00355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHA79_RS00390	COG1929	Belongs to the glycerate kinase type-1 family
KHA79_RS00400	COG0531	amino acid
KHA79_RS00405	COG4566	intracellular signal transduction
KHA79_RS00410	COG4191	Histidine kinase
KHA79_RS00415	COG1285	pathogenesis
KHA79_RS00430	COG1322	Protein conserved in bacteria
KHA79_RS00435	COG0386	Belongs to the glutathione peroxidase family
KHA79_RS00440	COG2853	Lipoprotein
KHA79_RS00455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KHA79_RS00460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KHA79_RS00465	COG1127	ABC transporter
KHA79_RS00470	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KHA79_RS00475	COG1074	ATP-dependent DNA helicase activity
KHA79_RS00480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHA79_RS00570	COG0840	transmembrane signaling receptor activity
KHA79_RS00575	COG0477	Major facilitator Superfamily
KHA79_RS00580	COG0302	gtp cyclohydrolase
KHA79_RS00585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHA79_RS00615	COG0730	response to heat
KHA79_RS00630	COG2951	lytic endotransglycosylase activity
KHA79_RS00635	COG0676	glucose-6-phosphate 1-epimerase activity
KHA79_RS00655	COG3135	benzoate transporter
KHA79_RS00690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHA79_RS00700	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_RS00705	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_RS00710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_RS00715	COG0493	'glutamate synthase
KHA79_RS00720	COG0067	glutamate synthase
KHA79_RS00720	COG0070	glutamate synthase
KHA79_RS00720	COG0069	glutamate synthase activity
KHA79_RS00765	COG1111	helicase
KHA79_RS00765	COG1205	dead DEAH box helicase
KHA79_RS00805	COG2271	Major facilitator Superfamily
KHA79_RS00855	COG1192	Involved in chromosome partitioning
KHA79_RS00860	COG2062	phosphohistidine phosphatase, SixA
KHA79_RS00870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHA79_RS00875	COG2050	protein possibly involved in aromatic compounds catabolism
KHA79_RS00885	COG2267	carboxylic ester hydrolase activity
KHA79_RS00900	COG1881	PFAM PEBP family protein
KHA79_RS00905	COG1968	undecaprenyl-diphosphatase activity
KHA79_RS00910	COG0174	glutamine synthetase
KHA79_RS00915	COG0347	Belongs to the P(II) protein family
KHA79_RS00920	COG0004	ammonium transporteR
KHA79_RS00925	COG3852	Histidine kinase
KHA79_RS00930	COG2204	response regulator
KHA79_RS00935	COG2032	superoxide dismutase activity
KHA79_RS00940	COG2032	superoxide dismutase activity
KHA79_RS00970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHA79_RS00975	COG1960	acyl-CoA dehydrogenase activity
KHA79_RS00985	COG3245	cytochrome
KHA79_RS01010	COG0523	cobalamin synthesis protein
KHA79_RS01015	COG0697	spore germination
KHA79_RS01025	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KHA79_RS01030	COG1846	Transcriptional regulator
KHA79_RS01035	COG1764	response to oxidative stress
KHA79_RS01045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHA79_RS01050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHA79_RS01070	COG2814	Major facilitator Superfamily
KHA79_RS01075	COG1404	Belongs to the peptidase S8 family
KHA79_RS01100	COG1902	pentaerythritol trinitrate reductase activity
KHA79_RS01105	COG2084	Dehydrogenase
KHA79_RS01130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHA79_RS01165	COG3228	Belongs to the MtfA family
KHA79_RS01175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KHA79_RS01175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KHA79_RS01180	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHA79_RS01210	COG3237	CsbD-like
KHA79_RS01220	COG0180	Tryptophanyl-tRNA synthetase
KHA79_RS01250	COG0339	signal peptide processing
KHA79_RS01265	COG0583	DNA-binding transcription factor activity
KHA79_RS01270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KHA79_RS01275	COG2224	Isocitrate lyase
KHA79_RS01310	COG0659	secondary active sulfate transmembrane transporter activity
KHA79_RS01345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHA79_RS01350	COG2130	NADP-dependent
KHA79_RS01365	COG1187	pseudouridine synthase activity
KHA79_RS01375	COG1643	Atp-dependent helicase
KHA79_RS01380	COG0084	hydrolase, TatD family'
KHA79_RS01395	COG0842	Transport permease protein
KHA79_RS01400	COG1131	(ABC) transporter
KHA79_RS01405	COG0633	Ferredoxin
KHA79_RS01405	COG0543	2 iron, 2 sulfur cluster binding
KHA79_RS01415	COG1476	TRANSCRIPTIONal
KHA79_RS01425	COG4555	ABC transporter
KHA79_RS01445	COG0625	glutathione transferase activity
KHA79_RS01515	COG1199	ATP-dependent helicase activity
KHA79_RS01555	COG0628	permease
KHA79_RS01565	COG0129	dihydroxy-acid dehydratase activity
KHA79_RS01570	COG2133	pyrroloquinoline quinone binding
KHA79_RS01630	COG5463	Belongs to the UPF0441 family
KHA79_RS01635	COG0754	glutathionylspermidine amidase activity
KHA79_RS01645	COG0714	Associated with various cellular activities
KHA79_RS01690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHA79_RS01705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS01710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_RS01770	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KHA79_RS01775	COG1040	competence protein
KHA79_RS01780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHA79_RS01810	COG0606	chelatase, subunit chli
KHA79_RS01815	COG2960	long-chain fatty acid transporting porin activity
KHA79_RS01840	COG1166	arginine decarboxylase activity
KHA79_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHA79_RS01850	COG1819	glycosyl
KHA79_RS01855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHA79_RS01855	COG2755	lipolytic protein G-D-S-L family
KHA79_RS01865	COG0583	DNA-binding transcription factor activity
KHA79_RS01880	COG4221	oxidoreductase activity
KHA79_RS01900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHA79_RS01920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHA79_RS01930	COG2814	Major facilitator Superfamily
KHA79_RS01945	COG0739	heme binding
KHA79_RS01950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHA79_RS01980	COG1064	alcohol dehydrogenase
KHA79_RS01985	COG2234	aminopeptidase activity
KHA79_RS01995	COG4942	peptidase
KHA79_RS02000	COG0793	Belongs to the peptidase S41A family
KHA79_RS02040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHA79_RS02045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHA79_RS02050	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KHA79_RS02080	COG0109	protoheme IX farnesyltransferase activity
KHA79_RS02095	COG0358	DNA primase activity
KHA79_RS02100	COG1295	ribonuclease BN
KHA79_RS02115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHA79_RS02120	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHA79_RS02125	COG2308	Evidence 4 Homologs of previously reported genes of
KHA79_RS02140	COG2133	pyrroloquinoline quinone binding
KHA79_RS02170	COG0531	amino acid
KHA79_RS02190	COG4771	TonB-dependent receptor
KHA79_RS02235	COG5383	Protein conserved in bacteria
KHA79_RS02250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_RS02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS02270	COG1652	LysM domain
KHA79_RS02280	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KHA79_RS02285	COG1518	maintenance of DNA repeat elements
KHA79_RS02340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHA79_RS02345	COG3118	belongs to the thioredoxin family
KHA79_RS02355	COG2884	Cell division ATP-binding protein ftsE
KHA79_RS02360	COG2177	Part of the ABC transporter FtsEX involved in
KHA79_RS02365	COG2201	protein-glutamate methylesterase activity
KHA79_RS02370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHA79_RS02375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHA79_RS02380	COG2860	membrane
KHA79_RS02385	COG1252	NADH dehydrogenase
KHA79_RS02395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHA79_RS02405	COG0534	Mate efflux family protein
KHA79_RS02410	COG0616	signal peptide processing
KHA79_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS02435	COG0009	L-threonylcarbamoyladenylate synthase
KHA79_RS02440	COG1754	DNA topoisomerase type I activity
KHA79_RS02440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHA79_RS02445	COG1714	RDD family
KHA79_RS02460	COG0758	DNA mediated transformation
KHA79_RS02465	COG1652	LysM domain
KHA79_RS02470	COG0242	peptide deformylase activity
KHA79_RS02475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHA79_RS02480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHA79_RS02480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHA79_RS02485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHA79_RS02535	COG1490	D-aminoacyl-tRNA deacylase activity
KHA79_RS02540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHA79_RS02565	COG1609	Transcriptional regulator
KHA79_RS02575	COG0366	Alpha amylase catalytic
KHA79_RS02580	COG0366	Alpha amylase catalytic
KHA79_RS02600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KHA79_RS02655	COG1309	transcriptional regulator
KHA79_RS02705	COG3546	catalase activity
KHA79_RS02710	COG3685	Protein conserved in bacteria
KHA79_RS02715	COG3685	Protein conserved in bacteria
KHA79_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS02730	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KHA79_RS02745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHA79_RS02760	COG0028	Belongs to the TPP enzyme family
KHA79_RS02765	COG4191	Histidine kinase
KHA79_RS02795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KHA79_RS02810	COG3645	SOS response
KHA79_RS02830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHA79_RS02830	COG1648	precorrin-2 dehydrogenase activity
KHA79_RS02840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHA79_RS02840	COG1116	anion transmembrane transporter activity
KHA79_RS02845	COG2223	nitrite transmembrane transporter activity
KHA79_RS02850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHA79_RS02855	COG2146	nitrite reductase [NAD(P)H] activity
KHA79_RS02860	COG0243	molybdopterin cofactor binding
KHA79_RS02885	COG1640	4-alpha-glucanotransferase
KHA79_RS02890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHA79_RS02900	COG0297	glycogen (starch) synthase activity
KHA79_RS02910	COG2204	response regulator
KHA79_RS02935	COG0181	hydroxymethylbilane synthase activity
KHA79_RS02950	COG1733	regulation of RNA biosynthetic process
KHA79_RS02965	COG1505	serine-type exopeptidase activity
KHA79_RS02970	COG0436	Aminotransferase
KHA79_RS02980	COG2832	Protein of unknown function (DUF454)
KHA79_RS03035	COG2226	methyltransferase
KHA79_RS03045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHA79_RS03050	COG0308	aminopeptidase N
KHA79_RS03055	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_RS03055	COG0596	Alpha beta hydrolase
KHA79_RS03075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHA79_RS03080	COG1077	Cell shape determining protein MreB Mrl
KHA79_RS03085	COG1792	Involved in formation and maintenance of cell shape
KHA79_RS03095	COG0768	penicillin binding
KHA79_RS03100	COG0772	Belongs to the SEDS family
KHA79_RS03110	COG5434	Belongs to the glycosyl hydrolase 28 family
KHA79_RS03115	COG2951	lytic endotransglycosylase activity
KHA79_RS03125	COG1686	Belongs to the peptidase S11 family
KHA79_RS03140	COG0321	lipoyl(octanoyl) transferase activity
KHA79_RS03145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KHA79_RS03170	COG1056	cytidyltransferase-related domain
KHA79_RS03170	COG1051	belongs to the nudix hydrolase family
KHA79_RS03190	COG1090	epimerase
KHA79_RS03200	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KHA79_RS03205	COG0673	inositol 2-dehydrogenase activity
KHA79_RS03210	COG2823	Periplasmic or secreted lipoprotein
KHA79_RS03220	COG2205	protein histidine kinase activity
KHA79_RS03220	COG2202	Pas domain
KHA79_RS03225	COG0784	Response regulator, receiver
KHA79_RS03230	COG4191	Histidine kinase
KHA79_RS03240	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHA79_RS03265	COG3250	beta-galactosidase activity
KHA79_RS03280	COG2188	Transcriptional regulator
KHA79_RS03290	COG1609	Transcriptional regulator
KHA79_RS03295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHA79_RS03300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHA79_RS03310	COG0617	tRNA 3'-terminal CCA addition
KHA79_RS03355	COG2207	Transcriptional regulator
KHA79_RS03380	COG2205	protein histidine kinase activity
KHA79_RS03395	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KHA79_RS03400	COG3791	Glutathione-dependent formaldehyde-activating
KHA79_RS03410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHA79_RS03420	COG0697	spore germination
KHA79_RS03465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KHA79_RS03490	COG0436	Aminotransferase
KHA79_RS03495	COG1162	GTPase activity
KHA79_RS03520	COG2211	Major facilitator Superfamily
KHA79_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS03535	COG2851	Citrate transporter
KHA79_RS03550	COG0642	Histidine kinase
KHA79_RS03580	COG1301	dicarboxylic acid transport
KHA79_RS03585	COG0281	malic enzyme
KHA79_RS03585	COG0280	phosphate acetyltransferase
KHA79_RS03655	COG1560	Kdo2-lipid A biosynthetic process
KHA79_RS03660	COG1519	Transferase
KHA79_RS03665	COG1538	Outer membrane efflux protein
KHA79_RS03670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KHA79_RS03680	COG3706	GGDEF domain
KHA79_RS03685	COG0473	3-isopropylmalate dehydrogenase activity
KHA79_RS03690	COG0066	3-isopropylmalate dehydratase activity
KHA79_RS03710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHA79_RS03735	COG0840	transmembrane signaling receptor activity
KHA79_RS03760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KHA79_RS03770	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KHA79_RS03790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KHA79_RS03800	COG0671	phosphoesterase, PA-phosphatase related
KHA79_RS03815	COG1940	carbohydrate kinase activity
KHA79_RS03825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHA79_RS03840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KHA79_RS03850	COG1773	rubredoxin
KHA79_RS03865	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHA79_RS03875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHA79_RS03900	COG3079	Belongs to the UPF0149 family
KHA79_RS03905	COG0006	proline dipeptidase activity
KHA79_RS03915	COG3038	cytochrome b561
KHA79_RS03920	COG1309	transcriptional regulator
KHA79_RS03925	COG0006	proline dipeptidase activity
KHA79_RS03940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHA79_RS03945	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHA79_RS03950	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHA79_RS03955	COG1561	YicC-like family, N-terminal region
KHA79_RS03960	COG0194	GDP metabolic process
KHA79_RS03965	COG1758	RNA polymerase activity
KHA79_RS03970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHA79_RS03995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHA79_RS04005	COG0254	rRNA binding
KHA79_RS04010	COG0372	Belongs to the citrate synthase family
KHA79_RS04020	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KHA79_RS04050	COG0714	Associated with various cellular activities
KHA79_RS04080	COG1301	dicarboxylic acid transport
KHA79_RS04085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHA79_RS04110	COG0739	heme binding
KHA79_RS04115	COG1376	ErfK ybiS ycfS ynhG family protein
KHA79_RS04155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KHA79_RS04160	COG4149	molybdate abc transporter
KHA79_RS04165	COG0725	ABC transporter, periplasmic molybdate-binding protein
KHA79_RS04175	COG0640	Transcriptional regulator
KHA79_RS04190	COG3047	cAMP biosynthetic process
KHA79_RS04195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KHA79_RS04240	COG0469	pyruvate kinase activity
KHA79_RS04245	COG3588	fructose-bisphosphate aldolase
KHA79_RS04250	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KHA79_RS04285	COG1648	precorrin-2 dehydrogenase activity
KHA79_RS04285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHA79_RS04300	COG2198	Histidine kinase
KHA79_RS04300	COG2205	protein histidine kinase activity
KHA79_RS04300	COG0784	Response regulator, receiver
KHA79_RS04305	COG1393	Belongs to the ArsC family
KHA79_RS04335	COG0175	sulfate reduction
KHA79_RS04340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHA79_RS04345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHA79_RS04355	COG2895	sulfate adenylyltransferase (ATP) activity
KHA79_RS04355	COG0529	Catalyzes the synthesis of activated sulfate
KHA79_RS04370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHA79_RS04385	COG1609	Transcriptional regulator
KHA79_RS04400	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHA79_RS04415	COG3273	potassium ion transport
KHA79_RS04415	COG0471	metal ion transport
KHA79_RS04425	COG2022	thiamine diphosphate biosynthetic process
KHA79_RS04445	COG0174	glutamine synthetase
KHA79_RS04450	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KHA79_RS04460	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHA79_RS04475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHA79_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS04505	COG3511	phospholipase C
KHA79_RS04515	COG0189	ligase activity
KHA79_RS04525	COG0745	RESPONSE REGULATOR receiver
KHA79_RS04540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KHA79_RS04605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KHA79_RS04605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHA79_RS04615	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KHA79_RS04630	COG1174	glycine betaine transport
KHA79_RS04635	COG1125	glycine betaine transport
KHA79_RS04645	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHA79_RS04650	COG0564	pseudouridine synthase activity
KHA79_RS04675	COG4993	Dehydrogenase
KHA79_RS04685	COG3387	PFAM Glycoside hydrolase 15-related
KHA79_RS04690	COG1877	trehalose-phosphatase activity
KHA79_RS04710	COG0454	-acetyltransferase
KHA79_RS04730	COG0542	response to heat
KHA79_RS04750	COG0019	diaminopimelate decarboxylase activity
KHA79_RS04755	COG4264	IucA IucC family
KHA79_RS04760	COG2814	Major facilitator Superfamily
KHA79_RS04765	COG4264	IucA IucC family
KHA79_RS04775	COG4772	TonB-dependent receptor
KHA79_RS04785	COG4651	solute:proton antiporter activity
KHA79_RS04785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHA79_RS04815	COG0488	(ABC) transporter
KHA79_RS04885	COG0217	transcriptional regulatory protein
KHA79_RS04895	COG0632	four-way junction helicase activity
KHA79_RS04900	COG3158	transport of potassium into the cell
KHA79_RS04905	COG2255	four-way junction helicase activity
KHA79_RS04910	COG0824	Thioesterase
KHA79_RS04920	COG0848	biopolymer transport protein
KHA79_RS04935	COG2885	chlorophyll binding
KHA79_RS04945	COG0602	queuosine metabolic process
KHA79_RS04950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KHA79_RS04970	COG0514	ATP-dependent DNA helicase (RecQ)
KHA79_RS04975	COG0783	Belongs to the Dps family
KHA79_RS04980	COG1643	Atp-dependent helicase
KHA79_RS05025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHA79_RS05050	COG1073	alpha beta
KHA79_RS05080	COG4638	Rieske (2fe-2S)
KHA79_RS05095	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KHA79_RS05110	COG1946	Acyl-CoA thioesterase
KHA79_RS05115	COG1024	Enoyl-CoA hydratase
KHA79_RS05125	COG0824	Thioesterase
KHA79_RS05130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHA79_RS05135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHA79_RS05140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHA79_RS05155	COG0728	peptidoglycan biosynthetic process
KHA79_RS05185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHA79_RS05205	COG0750	zinc metalloprotease
KHA79_RS05220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHA79_RS05225	COG1845	cytochrome c oxidase, subunit III
KHA79_RS05230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHA79_RS05250	COG3152	Membrane
KHA79_RS05305	COG4794	Type iii secretion
KHA79_RS05330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHA79_RS05355	COG1317	bacterial-type flagellum organization
KHA79_RS05375	COG2207	Transcriptional regulator
KHA79_RS05400	COG0129	dihydroxy-acid dehydratase activity
KHA79_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS05420	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_RS05425	COG1879	ABC-type sugar transport system periplasmic component
KHA79_RS05430	COG1129	ABC transporter
KHA79_RS05435	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHA79_RS05440	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHA79_RS05450	COG1082	Xylose isomerase domain protein TIM barrel
KHA79_RS05455	COG0625	glutathione transferase activity
KHA79_RS05475	COG0475	glutathione-regulated potassium exporter activity
KHA79_RS05500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHA79_RS05520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHA79_RS05530	COG0335	large ribosomal subunit rRNA binding
KHA79_RS05535	COG0534	Mate efflux family protein
KHA79_RS05555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KHA79_RS05560	COG2894	cell division
KHA79_RS05565	COG0850	regulation of cytokinetic process
KHA79_RS05575	COG4585	Histidine kinase
KHA79_RS05595	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHA79_RS05600	COG1216	Glycosyl transferase, family 2
KHA79_RS05605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHA79_RS05615	COG1199	ATP-dependent helicase activity
KHA79_RS05635	COG0189	ligase activity
KHA79_RS05650	COG0835	chemotaxis
KHA79_RS05655	COG0840	transmembrane signaling receptor activity
KHA79_RS05660	COG2198	Histidine kinase
KHA79_RS05660	COG0643	Histidine kinase
KHA79_RS05660	COG0784	Response regulator, receiver
KHA79_RS05665	COG2201	protein-glutamate methylesterase activity
KHA79_RS05685	COG1446	asparaginase
KHA79_RS05690	COG3142	Participates in the control of copper homeostasis
KHA79_RS05805	COG3537	Alpha-1,2-mannosidase
KHA79_RS05825	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_RS05835	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KHA79_RS05840	COG1388	LysM domain
KHA79_RS05840	COG3858	chitin binding
KHA79_RS05860	COG0837	glucose binding
KHA79_RS05870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KHA79_RS05880	COG0494	nUDIX hydrolase
KHA79_RS05885	COG1218	3'(2'),5'-bisphosphate nucleotidase
KHA79_RS05890	COG3956	TIGRFAM MazG family protein
KHA79_RS05895	COG1742	UPF0060 membrane protein
KHA79_RS05900	COG0330	HflC and HflK could
KHA79_RS05965	COG2124	cytochrome p450
KHA79_RS05970	COG2124	cytochrome p450
KHA79_RS05975	COG1141	Ferredoxin
KHA79_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS05985	COG2124	cytochrome p450
KHA79_RS05990	COG0142	geranyltranstransferase activity
KHA79_RS05995	COG1657	PFAM Prenyltransferase squalene oxidase
KHA79_RS06005	COG1304	FMN binding
KHA79_RS06010	COG1960	acyl-CoA dehydrogenase activity
KHA79_RS06045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHA79_RS06050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHA79_RS06055	COG0463	Glycosyl transferase, family 2
KHA79_RS06060	COG0517	IMP dehydrogenase activity
KHA79_RS06065	COG2982	Protein involved in outer membrane biogenesis
KHA79_RS06070	COG1272	protein, Hemolysin III
KHA79_RS06075	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHA79_RS06090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHA79_RS06095	COG0626	cystathionine gamma-synthase activity
KHA79_RS06105	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_RS06105	COG0596	Alpha beta hydrolase
KHA79_RS06115	COG1760	l-serine dehydratase
KHA79_RS06130	COG3038	cytochrome b561
KHA79_RS06145	COG0784	Response regulator, receiver
KHA79_RS06145	COG2198	Histidine kinase
KHA79_RS06145	COG2205	protein histidine kinase activity
KHA79_RS06150	COG2814	Major facilitator Superfamily
KHA79_RS06155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KHA79_RS06165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS06170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_RS06210	COG0789	Transcriptional regulator
KHA79_RS06230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHA79_RS06245	COG0519	Catalyzes the synthesis of GMP from XMP
KHA79_RS06260	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHA79_RS06280	COG0840	transmembrane signaling receptor activity
KHA79_RS06290	COG1113	amino acid transport
KHA79_RS06310	COG2239	Acts as a magnesium transporter
KHA79_RS06315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHA79_RS06320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHA79_RS06330	COG1660	Displays ATPase and GTPase activities
KHA79_RS06340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHA79_RS06355	COG1137	ATPase activity
KHA79_RS06370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KHA79_RS06415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHA79_RS06435	COG0628	permease
KHA79_RS06445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHA79_RS06450	COG3178	'Phosphotransferase
KHA79_RS06465	COG1555	photosystem II stabilization
KHA79_RS06490	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHA79_RS06495	COG1477	protein flavinylation
KHA79_RS06520	COG4774	siderophore transport
KHA79_RS06525	COG2146	nitrite reductase [NAD(P)H] activity
KHA79_RS06535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHA79_RS06540	COG0719	Fe-S assembly protein
KHA79_RS06545	COG0396	ATPase activity
KHA79_RS06550	COG0719	Fe-S assembly protein
KHA79_RS06565	COG0693	protein deglycase activity
KHA79_RS06580	COG0739	heme binding
KHA79_RS06595	COG1764	response to oxidative stress
KHA79_RS06605	COG0384	phenazine biosynthesis protein PhzF
KHA79_RS06610	COG0527	aspartate kinase activity
KHA79_RS06625	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHA79_RS06635	COG0142	geranyltranstransferase activity
KHA79_RS06640	COG0629	single-stranded DNA binding
KHA79_RS06655	COG1297	OPT oligopeptide transporter protein
KHA79_RS06660	COG0823	Involved in the tonB-independent uptake of proteins
KHA79_RS06660	COG1506	peptidase
KHA79_RS06675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHA79_RS06680	COG2879	small protein
KHA79_RS06685	COG1966	Carbon starvation protein
KHA79_RS06720	COG1515	deoxyribonuclease V activity
KHA79_RS06750	COG2203	Gaf domain
KHA79_RS06750	COG3706	GGDEF domain
KHA79_RS06750	COG4251	negative regulation of phosphorylation
KHA79_RS06750	COG5001	Diguanylate cyclase
KHA79_RS06755	COG0835	chemotaxis
KHA79_RS06760	COG0840	transmembrane signaling receptor activity
KHA79_RS06765	COG0840	transmembrane signaling receptor activity
KHA79_RS06775	COG2198	Histidine kinase
KHA79_RS06775	COG0643	Histidine kinase
KHA79_RS06785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHA79_RS06805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KHA79_RS06850	COG0735	belongs to the Fur family
KHA79_RS06920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHA79_RS06990	COG1187	pseudouridine synthase activity
KHA79_RS07015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KHA79_RS07035	COG1132	(ABC) transporter
KHA79_RS07100	COG1981	membrane
KHA79_RS07110	COG0825	malonyl-CoA metabolic process
KHA79_RS07130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHA79_RS07150	COG0750	zinc metalloprotease
KHA79_RS07155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KHA79_RS07160	COG0575	Belongs to the CDS family
KHA79_RS07165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHA79_RS07175	COG0528	UMP kinase activity
KHA79_RS07185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHA79_RS07225	COG0024	Methionine aminopeptidase
KHA79_RS07240	COG1393	Belongs to the ArsC family
KHA79_RS07245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHA79_RS07255	COG0367	asparagine synthase
KHA79_RS07290	COG1566	PFAM secretion protein HlyD family protein
KHA79_RS07295	COG2814	Major facilitator Superfamily
KHA79_RS07335	COG0557	exoribonuclease II activity
KHA79_RS07345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHA79_RS07370	COG0704	Plays a role in the regulation of phosphate uptake
KHA79_RS07380	COG0581	inorganic phosphate transmembrane transporter activity
KHA79_RS07395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHA79_RS07415	COG0659	secondary active sulfate transmembrane transporter activity
KHA79_RS07420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHA79_RS07430	COG1024	Enoyl-CoA hydratase
KHA79_RS07475	COG0116	Belongs to the methyltransferase superfamily
KHA79_RS07475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHA79_RS07485	COG2205	protein histidine kinase activity
KHA79_RS07485	COG5002	protein histidine kinase activity
KHA79_RS07485	COG0784	Response regulator, receiver
KHA79_RS07490	COG2733	membrane
KHA79_RS07510	COG0686	Belongs to the AlaDH PNT family
KHA79_RS07515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHA79_RS07520	COG1917	Cupin 2, conserved barrel domain protein
KHA79_RS07520	COG1396	sequence-specific DNA binding
KHA79_RS07525	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_RS07550	COG2223	nitrite transmembrane transporter activity
KHA79_RS07560	COG0243	molybdopterin cofactor binding
KHA79_RS07580	COG0477	Major facilitator Superfamily
KHA79_RS07590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_RS07595	COG0174	glutamine synthetase
KHA79_RS07600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHA79_RS07605	COG0174	glutamine synthetase
KHA79_RS07615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KHA79_RS07620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KHA79_RS07640	COG3842	ATPase activity
KHA79_RS07645	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHA79_RS07650	COG1177	transmembrane transport
KHA79_RS07655	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_RS07670	COG4535	Mg2 and Co2 transporter CorC
KHA79_RS07685	COG1702	phosphate starvation-inducible protein PhoH
KHA79_RS07700	COG0741	lytic transglycosylase activity
KHA79_RS07705	COG0723	plastoquinol--plastocyanin reductase activity
KHA79_RS07710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHA79_RS07720	COG2857	Cytochrome c1
KHA79_RS07725	COG0625	glutathione transferase activity
KHA79_RS07730	COG2969	positive regulation of protein catabolic process
KHA79_RS07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS07795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KHA79_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS07805	COG2095	MarC family integral membrane protein
KHA79_RS07815	COG1611	Belongs to the LOG family
KHA79_RS07820	COG3275	phosphorelay sensor kinase activity
KHA79_RS07870	COG0556	nucleotide-excision repair
KHA79_RS07985	COG1741	Belongs to the pirin family
KHA79_RS07990	COG0583	DNA-binding transcription factor activity
KHA79_RS08010	COG0351	phosphomethylpyrimidine kinase
KHA79_RS08025	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KHA79_RS08030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHA79_RS08040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHA79_RS08050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KHA79_RS08055	COG3734	2-keto-3-deoxy-galactonokinase
KHA79_RS08070	COG0800	Aldolase
KHA79_RS08085	COG1070	Carbohydrate kinase
KHA79_RS08090	COG2115	Belongs to the xylose isomerase family
KHA79_RS08095	COG0477	Major facilitator Superfamily
KHA79_RS08105	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHA79_RS08125	COG0617	tRNA 3'-terminal CCA addition
KHA79_RS08135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KHA79_RS08150	COG0166	Belongs to the GPI family
KHA79_RS08245	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KHA79_RS08260	COG0671	phosphoesterase, PA-phosphatase related
KHA79_RS08285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KHA79_RS08290	COG0167	dihydroorotate dehydrogenase activity
KHA79_RS08305	COG1012	belongs to the aldehyde dehydrogenase family
KHA79_RS08320	COG0460	homoserine dehydrogenase
KHA79_RS08320	COG0527	aspartate kinase activity
KHA79_RS08330	COG2951	lytic endotransglycosylase activity
KHA79_RS08340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHA79_RS08350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHA79_RS08355	COG0124	histidyl-tRNA synthetase
KHA79_RS08365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KHA79_RS08370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHA79_RS08375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHA79_RS08385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHA79_RS08400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHA79_RS08400	COG0140	phosphoribosyl-ATP diphosphatase activity
KHA79_RS08415	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KHA79_RS08420	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KHA79_RS08425	COG0235	Class ii aldolase
KHA79_RS08430	COG0531	amino acid
KHA79_RS08435	COG0531	amino acid
KHA79_RS08450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHA79_RS08455	COG0277	FAD linked oxidase domain protein
KHA79_RS08475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHA79_RS08495	COG1024	Enoyl-CoA hydratase
KHA79_RS08540	COG0348	domain, Protein
KHA79_RS08550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHA79_RS08560	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KHA79_RS08565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHA79_RS08575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHA79_RS08615	COG1136	(ABC) transporter
KHA79_RS08615	COG0577	efflux transmembrane transporter activity
KHA79_RS08645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHA79_RS08645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KHA79_RS08650	COG1105	Belongs to the carbohydrate kinase PfkB family
KHA79_RS08655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHA79_RS08655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHA79_RS08660	COG1609	Transcriptional regulator
KHA79_RS08670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KHA79_RS08675	COG0069	glutamate synthase activity
KHA79_RS08685	COG5002	protein histidine kinase activity
KHA79_RS08685	COG3447	MASE1 domain protein
KHA79_RS08685	COG5001	Diguanylate cyclase
KHA79_RS08715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHA79_RS08730	COG1253	flavin adenine dinucleotide binding
KHA79_RS08760	COG0504	CTP synthase activity
KHA79_RS08765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KHA79_RS08780	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHA79_RS08785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHA79_RS08800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KHA79_RS08810	COG1238	metal cluster binding
KHA79_RS08825	COG1534	Rna-binding protein
KHA79_RS08830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KHA79_RS08835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHA79_RS08840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHA79_RS08855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHA79_RS08860	COG1546	Belongs to the CinA family
KHA79_RS08865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KHA79_RS08870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHA79_RS08875	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHA79_RS08880	COG2137	regulation of response to DNA damage stimulus
KHA79_RS08885	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHA79_RS08890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KHA79_RS08925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHA79_RS08935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHA79_RS08940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHA79_RS08990	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS08995	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS09005	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS09025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHA79_RS09035	COG1960	acyl-CoA dehydrogenase activity
KHA79_RS09080	COG1570	exodeoxyribonuclease VII activity
KHA79_RS09085	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHA79_RS09090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHA79_RS09090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHA79_RS09095	COG0802	atpase or kinase
KHA79_RS09100	COG0860	N-Acetylmuramoyl-L-alanine amidase
KHA79_RS09105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHA79_RS09125	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS09145	COG2081	HI0933 family
KHA79_RS09150	COG4681	YaeQ
KHA79_RS09155	COG0564	pseudouridine synthase activity
KHA79_RS09165	COG0625	glutathione transferase activity
KHA79_RS09170	COG0657	acetylesterase activity
KHA79_RS09175	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KHA79_RS09200	COG0513	Belongs to the DEAD box helicase family
KHA79_RS09205	COG0488	(ABC) transporter
KHA79_RS09220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHA79_RS09230	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_RS09275	COG1846	Transcriptional regulator
KHA79_RS09295	COG0386	Belongs to the glutathione peroxidase family
KHA79_RS09320	COG1595	DNA-templated transcription, initiation
KHA79_RS09360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KHA79_RS09375	COG0505	Belongs to the CarA family
KHA79_RS09385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHA79_RS09390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHA79_RS09410	COG4676	Protein conserved in bacteria
KHA79_RS09460	COG3279	Response regulator of the LytR AlgR family
KHA79_RS09480	COG2205	protein histidine kinase activity
KHA79_RS09480	COG2198	Histidine kinase
KHA79_RS09480	COG0784	Response regulator, receiver
KHA79_RS09485	COG1024	Enoyl-CoA hydratase
KHA79_RS09490	COG0318	PFAM AMP-dependent synthetase and ligase
KHA79_RS09565	COG0840	transmembrane signaling receptor activity
KHA79_RS09575	COG0835	chemotaxis
KHA79_RS09585	COG0840	transmembrane signaling receptor activity
KHA79_RS09600	COG0840	transmembrane signaling receptor activity
KHA79_RS09615	COG0840	transmembrane signaling receptor activity
KHA79_RS09625	COG0840	transmembrane signaling receptor activity
KHA79_RS09640	COG0840	transmembrane signaling receptor activity
KHA79_RS09655	COG0745	RESPONSE REGULATOR receiver
KHA79_RS09665	COG0835	chemotaxis
KHA79_RS09675	COG1360	Flagellar Motor Protein
KHA79_RS09680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHA79_RS09685	COG2198	Histidine kinase
KHA79_RS09685	COG0643	Histidine kinase
KHA79_RS09685	COG0784	Response regulator, receiver
KHA79_RS09690	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KHA79_RS09735	COG1684	flagellar biosynthetic protein fliR
KHA79_RS09740	COG1987	bacterial-type flagellum assembly
KHA79_RS09750	COG3190	flagellar
KHA79_RS09800	COG1677	Flagellar hook-basal body complex protein FliE
KHA79_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS09845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_RS09865	COG2201	protein-glutamate methylesterase activity
KHA79_RS09870	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KHA79_RS09875	COG2197	response regulator
KHA79_RS09895	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KHA79_RS09900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHA79_RS09905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHA79_RS09910	COG1256	bacterial-type flagellum assembly
KHA79_RS09910	COG1256	bacterial-type flagellum assembly
KHA79_RS09910	COG4786	Flagellar basal body rod
KHA79_RS09910	COG4786	Flagellar basal body rod
KHA79_RS09925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KHA79_RS09940	COG1749	Flagellar hook protein flgE
KHA79_RS09950	COG1558	bacterial-type flagellum-dependent cell motility
KHA79_RS09960	COG0784	Response regulator, receiver
KHA79_RS09960	COG0835	chemotaxis
KHA79_RS10005	COG1116	anion transmembrane transporter activity
KHA79_RS10020	COG2915	High frequency lysogenization protein hflD homolog
KHA79_RS10025	COG0482	sulfurtransferase activity
KHA79_RS10045	COG0542	response to heat
KHA79_RS10065	COG0492	ferredoxin-NADP+ reductase activity
KHA79_RS10070	COG1674	ftsk spoiiie
KHA79_RS10090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHA79_RS10095	COG0038	chloride channel
KHA79_RS10145	COG1595	DNA-templated transcription, initiation
KHA79_RS10165	COG3038	cytochrome b561
KHA79_RS10195	COG2244	polysaccharide biosynthetic process
KHA79_RS10200	COG1215	transferase activity, transferring glycosyl groups
KHA79_RS10215	COG4106	trans-aconitate 2-methyltransferase activity
KHA79_RS10225	COG2264	protein methyltransferase activity
KHA79_RS10230	COG0297	glycogen (starch) synthase activity
KHA79_RS10235	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS10255	COG1132	(ABC) transporter
KHA79_RS10275	COG0512	Glutamine amidotransferase of anthranilate synthase
KHA79_RS10435	COG1649	PFAM Uncharacterised BCR, COG1649
KHA79_RS10505	COG2205	protein histidine kinase activity
KHA79_RS10505	COG0784	Response regulator, receiver
KHA79_RS10510	COG2183	response to ionizing radiation
KHA79_RS10515	COG0784	Response regulator, receiver
KHA79_RS10515	COG4191	Histidine kinase
KHA79_RS10525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_RS10525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KHA79_RS10545	COG3243	poly(R)-hydroxyalkanoic acid synthase
KHA79_RS10555	COG1183	phosphatidylcholine synthase activity
KHA79_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS10585	COG0668	transmembrane transport
KHA79_RS10590	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHA79_RS10605	COG1914	H( )-stimulated, divalent metal cation uptake system
KHA79_RS10615	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KHA79_RS10620	COG1501	Belongs to the glycosyl hydrolase 31 family
KHA79_RS10625	COG2207	Transcriptional regulator
KHA79_RS10635	COG1538	Outer membrane efflux protein
KHA79_RS10640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_RS10645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS10650	COG4773	Receptor
KHA79_RS10670	COG1487	ribonuclease activity
KHA79_RS10675	COG4691	Plasmid stability protein
KHA79_RS10695	COG5599	Phosphatase
KHA79_RS10710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHA79_RS10740	COG4773	Receptor
KHA79_RS10745	COG0475	glutathione-regulated potassium exporter activity
KHA79_RS10745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHA79_RS10750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHA79_RS10760	COG0746	molybdenum cofactor guanylyltransferase activity
KHA79_RS10770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHA79_RS10780	COG1426	Protein conserved in bacteria
KHA79_RS10790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHA79_RS10805	COG1024	Enoyl-CoA hydratase
KHA79_RS10805	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHA79_RS10810	COG0183	Belongs to the thiolase family
KHA79_RS10815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHA79_RS10825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHA79_RS10830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KHA79_RS10840	COG0776	regulation of translation
KHA79_RS10845	COG0539	negative regulation of cytoplasmic translation
KHA79_RS10850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHA79_RS10855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHA79_RS10865	COG2957	Belongs to the agmatine deiminase family
KHA79_RS10870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHA79_RS10910	COG0316	Belongs to the HesB IscA family
KHA79_RS10910	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHA79_RS10925	COG0428	transporter
KHA79_RS10930	COG3064	Membrane
KHA79_RS10940	COG1530	ribonuclease E activity
KHA79_RS10980	COG1605	Chorismate mutase
KHA79_RS10980	COG0077	Prephenate dehydratase
KHA79_RS10985	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHA79_RS10990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHA79_RS11030	COG4221	oxidoreductase activity
KHA79_RS11060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHA79_RS11095	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KHA79_RS11105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KHA79_RS11110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHA79_RS11115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHA79_RS11150	COG0316	Belongs to the HesB IscA family
KHA79_RS11220	COG0288	reversible hydration of carbon dioxide
KHA79_RS11225	COG0662	Cupin 2, conserved barrel domain protein
KHA79_RS11235	COG3844	kynureninase activity
KHA79_RS11245	COG2925	Exonuclease
KHA79_RS11285	COG2902	Dehydrogenase
KHA79_RS11295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS11300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHA79_RS11305	COG1960	acyl-CoA dehydrogenase activity
KHA79_RS11310	COG2226	methyltransferase
KHA79_RS11315	COG0646	methionine synthase
KHA79_RS11315	COG1410	methionine synthase
KHA79_RS11320	COG0646	methionine synthase
KHA79_RS11320	COG1410	methionine synthase
KHA79_RS11330	COG2755	lipolytic protein G-D-S-L family
KHA79_RS11330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHA79_RS11340	COG2900	Belongs to the SlyX family
KHA79_RS11355	COG0386	Belongs to the glutathione peroxidase family
KHA79_RS11365	COG1725	Transcriptional regulator
KHA79_RS11370	COG1131	(ABC) transporter
KHA79_RS11410	COG2850	peptidyl-arginine hydroxylation
KHA79_RS11420	COG0567	Dehydrogenase, E1 component
KHA79_RS11430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHA79_RS11445	COG2826	transposase and inactivated derivatives, IS30 family
KHA79_RS11470	COG1132	(ABC) transporter
KHA79_RS11480	COG0287	Prephenate dehydrogenase
KHA79_RS11480	COG1605	Chorismate mutase
KHA79_RS11485	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KHA79_RS11490	COG0484	heat shock protein binding
KHA79_RS11495	COG0443	Heat shock 70 kDa protein
KHA79_RS11500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHA79_RS11505	COG1420	regulation of RNA biosynthetic process
KHA79_RS11510	COG0497	DNA recombination
KHA79_RS11515	COG0735	belongs to the Fur family
KHA79_RS11520	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHA79_RS11530	COG2867	negative regulation of translational initiation
KHA79_RS11535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHA79_RS11540	COG1404	Belongs to the peptidase S8 family
KHA79_RS11580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHA79_RS11595	COG0583	DNA-binding transcription factor activity
KHA79_RS11610	COG0415	Belongs to the DNA photolyase family
KHA79_RS11615	COG0305	Participates in initiation and elongation during chromosome replication
KHA79_RS11625	COG1960	acyl-CoA dehydrogenase activity
KHA79_RS11640	COG0084	hydrolase, TatD family'
KHA79_RS11645	COG2258	MOSC domain
KHA79_RS11650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHA79_RS11965	COG3209	COG3209 Rhs family protein
KHA79_RS11980	COG3209	COG3209 Rhs family protein
KHA79_RS11990	COG3209	COG3209 Rhs family protein
KHA79_RS12015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHA79_RS12030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHA79_RS12040	COG1663	tetraacyldisaccharide 4'-kinase activity
KHA79_RS12045	COG1132	(ABC) transporter
KHA79_RS12055	COG0811	peptide transport
KHA79_RS12075	COG4591	ABC-type transport system involved in lipoprotein release permease component
KHA79_RS12090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KHA79_RS12100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KHA79_RS12105	COG2009	succinate dehydrogenase
KHA79_RS12115	COG0354	folic acid binding
KHA79_RS12120	COG3842	ATPase activity
KHA79_RS12125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHA79_RS12140	COG0129	dihydroxy-acid dehydratase activity
KHA79_RS12145	COG0800	Aldolase
KHA79_RS12155	COG0395	ABC-type sugar transport system, permease component
KHA79_RS12190	COG2350	Protein conserved in bacteria
KHA79_RS12195	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHA79_RS12200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHA79_RS12205	COG1187	pseudouridine synthase activity
KHA79_RS12225	COG0436	Aminotransferase
KHA79_RS12230	COG4133	protoheme IX ABC transporter activity
KHA79_RS12275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHA79_RS12280	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHA79_RS12285	COG4988	ABC transporter
KHA79_RS12295	COG1294	oxidase, subunit
KHA79_RS12325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHA79_RS12345	COG0165	Argininosuccinate lyase
KHA79_RS12350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHA79_RS12360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KHA79_RS12365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHA79_RS12370	COG0137	argininosuccinate synthase activity
KHA79_RS12375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHA79_RS12390	COG2166	iron-sulfur cluster assembly
KHA79_RS12395	COG2814	Major facilitator Superfamily
KHA79_RS12420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KHA79_RS12430	COG4677	pectinesterase activity
KHA79_RS12455	COG0402	S-adenosylhomocysteine deaminase activity
KHA79_RS12460	COG3548	integral membrane protein
KHA79_RS12470	COG1509	lysine 2,3-aminomutase activity
KHA79_RS12475	COG3706	GGDEF domain
KHA79_RS12475	COG4251	negative regulation of phosphorylation
KHA79_RS12475	COG5001	Diguanylate cyclase
KHA79_RS12475	COG2203	Gaf domain
KHA79_RS12505	COG1862	Preprotein translocase
KHA79_RS12515	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHA79_RS12525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHA79_RS12540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHA79_RS12545	COG3291	Pkd domain containing protein
KHA79_RS12550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHA79_RS12555	COG0405	Gamma-glutamyltransferase
KHA79_RS12560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KHA79_RS12575	COG0742	ribosomal rna small subunit methyltransferase
KHA79_RS12605	COG4771	TonB-dependent receptor
KHA79_RS12665	COG0531	amino acid
KHA79_RS12680	COG0006	proline dipeptidase activity
KHA79_RS12690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHA79_RS12705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_RS12710	COG3938	Belongs to the proline racemase family
KHA79_RS12720	COG0552	protein localization to endoplasmic reticulum
KHA79_RS12770	COG0835	chemotaxis
KHA79_RS12775	COG0840	transmembrane signaling receptor activity
KHA79_RS12780	COG0840	transmembrane signaling receptor activity
KHA79_RS12800	COG1201	RNA secondary structure unwinding
KHA79_RS12820	COG5001	Diguanylate cyclase
KHA79_RS12820	COG3300	MHYT domain
KHA79_RS12825	COG1185	polyribonucleotide nucleotidyltransferase activity
KHA79_RS12850	COG0195	Participates in both transcription termination and antitermination
KHA79_RS12865	COG1007	ATP synthesis coupled electron transport
KHA79_RS12900	COG1034	ATP synthesis coupled electron transport
KHA79_RS12905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KHA79_RS12910	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KHA79_RS12915	COG0649	NAD binding
KHA79_RS12920	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHA79_RS12930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHA79_RS12960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHA79_RS13000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHA79_RS13015	COG2890	protein-(glutamine-N5) methyltransferase activity
KHA79_RS13025	COG0688	phosphatidylethanolamine metabolic process
KHA79_RS13035	COG0433	COG0433 Predicted ATPase
KHA79_RS13045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHA79_RS13075	COG0717	Belongs to the dCTP deaminase family
KHA79_RS13080	COG0489	protein tyrosine kinase activity
KHA79_RS13085	COG4771	TonB-dependent receptor
KHA79_RS13090	COG4771	TonB-dependent receptor
KHA79_RS13095	COG0457	Tetratricopeptide repeat
KHA79_RS13105	COG3590	peptidase
KHA79_RS13125	COG0697	spore germination
KHA79_RS13145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_RS13150	COG2311	Membrane
KHA79_RS13155	COG1047	Peptidyl-prolyl cis-trans
KHA79_RS13160	COG0791	NLP P60 protein
KHA79_RS13165	COG0791	NLP P60 protein
KHA79_RS13180	COG1607	acyl-coa hydrolase
KHA79_RS13185	COG2226	methyltransferase
KHA79_RS13190	COG1301	dicarboxylic acid transport
KHA79_RS13195	COG1785	Belongs to the alkaline phosphatase family
KHA79_RS13205	COG0037	tRNA processing
KHA79_RS13210	COG1722	exodeoxyribonuclease VII activity
KHA79_RS13215	COG0142	geranyltranstransferase activity
KHA79_RS13220	COG4104	PAAR repeat-containing protein
KHA79_RS13230	COG1858	cytochrome C peroxidase
KHA79_RS13235	COG3852	Histidine kinase
KHA79_RS13255	COG2815	serine threonine protein kinase
KHA79_RS13255	COG0515	serine threonine protein kinase
KHA79_RS13260	COG0631	protein serine/threonine phosphatase activity
KHA79_RS13355	COG0312	modulator of DNA gyrase
KHA79_RS13365	COG0312	modulator of DNA gyrase
KHA79_RS13385	COG2968	Membrane
KHA79_RS13400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHA79_RS13415	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHA79_RS13430	COG0495	leucyl-tRNA aminoacylation
KHA79_RS13440	COG3118	belongs to the thioredoxin family
KHA79_RS13455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHA79_RS13465	COG2040	homocysteine
KHA79_RS13475	COG0346	lactoylglutathione lyase activity
KHA79_RS13480	COG1131	(ABC) transporter
KHA79_RS13505	COG2878	Part of a membrane complex involved in electron transport
KHA79_RS13520	COG1595	DNA-templated transcription, initiation
KHA79_RS13545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KHA79_RS13565	COG0251	oxidation-reduction process
KHA79_RS13575	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHA79_RS13575	COG0392	lysyltransferase activity
KHA79_RS13605	COG2814	Major facilitator Superfamily
KHA79_RS13610	COG1902	pentaerythritol trinitrate reductase activity
KHA79_RS13615	COG2824	Alkylphosphonate utilization operon protein PhnA
KHA79_RS13620	COG1047	Peptidyl-prolyl cis-trans
KHA79_RS13625	COG1077	Cell shape determining protein MreB Mrl
KHA79_RS13660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KHA79_RS13670	COG1451	nucleotide metabolic process
KHA79_RS13690	COG2205	protein histidine kinase activity
KHA79_RS13700	COG2186	Transcriptional regulator
KHA79_RS13705	COG3250	beta-galactosidase activity
KHA79_RS13755	COG1703	isobutyryl-CoA mutase activity
KHA79_RS13755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHA79_RS13755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHA79_RS13780	COG0183	Belongs to the thiolase family
KHA79_RS13825	COG1793	dna ligase
KHA79_RS13825	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KHA79_RS13830	COG1793	dna ligase
KHA79_RS13830	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KHA79_RS13835	COG1201	RNA secondary structure unwinding
KHA79_RS13845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHA79_RS13850	COG1278	Cold shock
KHA79_RS13855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHA79_RS13860	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KHA79_RS13865	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_RS13870	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KHA79_RS13875	COG2954	triphosphatase activity
KHA79_RS13885	COG0745	RESPONSE REGULATOR receiver
KHA79_RS13890	COG1381	Involved in DNA repair and RecF pathway recombination
KHA79_RS13895	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHA79_RS13915	COG0481	GTPase activity
KHA79_RS13920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHA79_RS13935	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHA79_RS13935	COG1024	Enoyl-CoA hydratase
KHA79_RS13950	COG2855	membrane
KHA79_RS14030	COG1074	ATP-dependent DNA helicase activity
KHA79_RS14085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHA79_RS14230	COG1196	nuclear chromosome segregation
KHA79_RS14340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHA79_RS14360	COG2205	protein histidine kinase activity
KHA79_RS14365	COG0745	RESPONSE REGULATOR receiver
KHA79_RS14375	COG2194	sulfuric ester hydrolase activity
KHA79_RS14395	COG2814	Major facilitator Superfamily
KHA79_RS14420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHA79_RS14420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHA79_RS14425	COG0753	catalase activity
KHA79_RS14450	COG1063	alcohol dehydrogenase
KHA79_RS14460	COG3459	Glycosyltransferase 36 associated
KHA79_RS14505	COG3177	Filamentation induced by cAMP protein fic
KHA79_RS14510	COG3586	endonuclease activity
KHA79_RS14570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHA79_RS14580	COG0330	HflC and HflK could
KHA79_RS14585	COG0330	HflC and HflK could
KHA79_RS14590	COG0604	alcohol dehydrogenase
KHA79_RS14610	COG0678	peroxiredoxin activity
KHA79_RS14620	COG4953	penicillin-binding protein 1C
KHA79_RS14640	COG2373	Large extracellular alpha-helical protein
KHA79_RS14670	COG3609	addiction module antidote protein, CC2985 family
KHA79_RS14695	COG0372	Belongs to the citrate synthase family
KHA79_RS14700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHA79_RS14715	COG0587	DNA-directed DNA polymerase activity
KHA79_RS14755	COG2161	toxin-antitoxin pair type II binding
KHA79_RS14760	COG4115	mRNA cleavage
KHA79_RS14780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHA79_RS14785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHA79_RS14790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHA79_RS14800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHA79_RS14805	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS14810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHA79_RS14815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_RS14820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHA79_RS14825	COG1399	metal-binding, possibly nucleic acid-binding protein
KHA79_RS14840	COG0714	Associated with various cellular activities
KHA79_RS14860	COG0537	adenosine 5'-monophosphoramidase activity
KHA79_RS14910	COG0314	molybdopterin synthase activity
KHA79_RS14915	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KHA79_RS14920	COG0315	cyclic pyranopterin monophosphate synthase activity
KHA79_RS14930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KHA79_RS14935	COG1234	tRNA 3'-trailer cleavage
KHA79_RS14945	COG0859	PFAM glycosyl transferase family 9
KHA79_RS14960	COG0631	protein serine/threonine phosphatase activity
KHA79_RS14970	COG0328	RNA-DNA hybrid ribonuclease activity
KHA79_RS14980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHA79_RS14985	COG3942	CHAP domain
KHA79_RS14985	COG1388	LysM domain
KHA79_RS15020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHA79_RS15030	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHA79_RS15065	COG0473	3-isopropylmalate dehydrogenase activity
KHA79_RS15080	COG4783	chaperone-mediated protein folding
KHA79_RS15095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHA79_RS15100	COG0248	Ppx GppA phosphatase
KHA79_RS15105	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS15115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHA79_RS15130	COG2833	Protein of unknown function (DUF455)
KHA79_RS15150	COG0285	dihydrofolate synthase activity
KHA79_RS15155	COG0588	phosphoglycerate mutase activity
KHA79_RS15175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KHA79_RS15180	COG4208	sulfate ABC transporter
KHA79_RS15185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KHA79_RS15195	COG0156	8-amino-7-oxononanoate synthase activity
KHA79_RS15200	COG1187	pseudouridine synthase activity
KHA79_RS15210	COG2885	chlorophyll binding
KHA79_RS15215	COG0583	DNA-binding transcription factor activity
KHA79_RS15220	COG2814	Major facilitator Superfamily
KHA79_RS15230	COG0667	Aldo Keto reductase
KHA79_RS15240	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHA79_RS15240	COG1902	pentaerythritol trinitrate reductase activity
KHA79_RS15265	COG0584	glycerophosphoryl diester phosphodiesterase
KHA79_RS15285	COG0625	glutathione transferase activity
KHA79_RS15300	COG0039	L-malate dehydrogenase activity
KHA79_RS15310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHA79_RS15315	COG1217	gtp-binding protein TYPA
KHA79_RS15335	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KHA79_RS15345	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KHA79_RS15350	COG0203	ribosomal protein L17
KHA79_RS15360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHA79_RS15375	COG0201	protein transport
KHA79_RS15385	COG1841	ribosomal large subunit assembly
KHA79_RS15415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHA79_RS15420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHA79_RS15430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHA79_RS15435	COG0255	Belongs to the universal ribosomal protein uL29 family
KHA79_RS15460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHA79_RS15465	COG0089	rRNA binding
KHA79_RS15470	COG0088	Forms part of the polypeptide exit tunnel
KHA79_RS15480	COG0051	transcription antitermination factor activity, RNA binding
KHA79_RS15485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHA79_RS15490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHA79_RS15505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHA79_RS15515	COG0222	ribosome binding
KHA79_RS15530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHA79_RS15535	COG0250	Participates in transcription elongation, termination and antitermination
KHA79_RS15540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHA79_RS15550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHA79_RS15570	COG0012	GTP binding
KHA79_RS15575	COG0193	aminoacyl-tRNA hydrolase activity
KHA79_RS15585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHA79_RS15610	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KHA79_RS15615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHA79_RS15625	COG5297	Belongs to the glycosyl hydrolase family 6
KHA79_RS15630	COG0521	Mo-molybdopterin cofactor biosynthetic process
KHA79_RS15650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHA79_RS15655	COG1295	ribonuclease BN
KHA79_RS15675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHA79_RS15685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHA79_RS15760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHA79_RS15760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHA79_RS15795	COG2890	protein-(glutamine-N5) methyltransferase activity
KHA79_RS15805	COG3634	alkyl hydroperoxide reductase activity
KHA79_RS15810	COG0583	DNA-binding transcription factor activity
KHA79_RS15820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHA79_RS15825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHA79_RS15830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHA79_RS15860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHA79_RS15865	COG0697	spore germination
KHA79_RS15890	COG0673	inositol 2-dehydrogenase activity
KHA79_RS15910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHA79_RS15915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHA79_RS15925	COG2096	Adenosyltransferase
KHA79_RS15940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHA79_RS15945	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KHA79_RS15950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHA79_RS15955	COG2967	ApaG domain
KHA79_RS15960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KHA79_RS15990	COG1704	LemA family
KHA79_RS15995	COG0861	Integral membrane protein TerC family
KHA79_RS16000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KHA79_RS16010	COG0642	Histidine kinase
KHA79_RS16025	COG4181	ATPase activity
KHA79_RS16030	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KHA79_RS16050	COG4771	TonB-dependent receptor
KHA79_RS16060	COG0667	Aldo Keto reductase
KHA79_RS16065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHA79_RS16085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHA79_RS16110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHA79_RS16180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KHA79_RS16190	COG0494	nUDIX hydrolase
KHA79_RS16205	COG0739	heme binding
KHA79_RS16215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KHA79_RS16220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHA79_RS16230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KHA79_RS16235	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHA79_RS16245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHA79_RS16260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHA79_RS16275	COG3116	cell division
KHA79_RS16280	COG0275	rRNA processing
KHA79_RS16285	COG2001	Belongs to the MraZ family
KHA79_RS16310	COG0792	nuclease activity
KHA79_RS16320	COG0277	FAD linked oxidase domain protein
KHA79_RS16325	COG0745	RESPONSE REGULATOR receiver
KHA79_RS16330	COG2205	protein histidine kinase activity
KHA79_RS16340	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KHA79_RS16345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KHA79_RS16370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KHA79_RS16375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHA79_RS16380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KHA79_RS16395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHA79_RS16395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHA79_RS16405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHA79_RS16430	COG0488	(ABC) transporter
KHA79_RS16435	COG0242	peptide deformylase activity
KHA79_RS16460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHA79_RS16470	COG1215	transferase activity, transferring glycosyl groups
KHA79_RS16480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KHA79_RS16540	COG2188	Transcriptional regulator
KHA79_RS16550	COG1450	Type ii and iii secretion system protein
KHA79_RS16565	COG3166	PFAM Fimbrial assembly family protein
KHA79_RS16570	COG3156	type II secretion system protein K
KHA79_RS16575	COG4795	General secretion pathway protein
KHA79_RS16580	COG2165	general secretion pathway protein
KHA79_RS16585	COG4970	Tfp pilus assembly protein FimT
KHA79_RS16590	COG2165	general secretion pathway protein
KHA79_RS16595	COG1459	type II secretion system
KHA79_RS16600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHA79_RS16605	COG1404	Belongs to the peptidase S8 family
KHA79_RS16610	COG5295	Hep Hag repeat protein
KHA79_RS16620	COG0840	transmembrane signaling receptor activity
KHA79_RS16625	COG0047	phosphoribosylformylglycinamidine synthase activity
KHA79_RS16625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHA79_RS16630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KHA79_RS16635	COG4974	Belongs to the 'phage' integrase family
KHA79_RS16660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHA79_RS16695	COG1183	phosphatidylcholine synthase activity
KHA79_RS16705	COG0442	prolyl-tRNA aminoacylation
KHA79_RS16720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KHA79_RS16725	COG1127	ABC transporter
KHA79_RS16730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KHA79_RS16730	COG3218	ABC-type transport auxiliary lipoprotein component
KHA79_RS16760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHA79_RS16765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHA79_RS16770	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KHA79_RS16770	COG0662	Cupin 2, conserved barrel domain protein
KHA79_RS16795	COG2086	electron transfer activity
KHA79_RS16810	COG0546	phosphoglycolate phosphatase activity
KHA79_RS16810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KHA79_RS16815	COG0277	FAD linked oxidase domain protein
KHA79_RS16820	COG0300	oxidoreductase activity
KHA79_RS16845	COG0493	'glutamate synthase
KHA79_RS16880	COG1216	Glycosyl transferase, family 2
KHA79_RS16880	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS16885	COG0438	transferase activity, transferring glycosyl groups
KHA79_RS16885	COG1216	Glycosyl transferase, family 2
KHA79_RS16890	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHA79_RS16905	COG0626	cystathionine gamma-synthase activity
KHA79_RS16935	COG0625	glutathione transferase activity
KHA79_RS16950	COG0720	synthase
KHA79_RS16960	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KHA79_RS16965	COG1956	GAF domain-containing protein
KHA79_RS16975	COG4206	TonB-dependent receptor
KHA79_RS17020	COG0339	signal peptide processing
KHA79_RS17025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHA79_RS17035	COG2217	Heavy metal translocating P-type atpase
KHA79_RS17050	COG2132	Multicopper oxidase
KHA79_RS17065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHA79_RS17090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHA79_RS17105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHA79_RS17120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHA79_RS17130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHA79_RS17140	COG0356	it plays a direct role in the translocation of protons across the membrane
KHA79_RS17155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHA79_RS17160	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_RS17190	COG2011	ABC-type metal ion transport system permease component
KHA79_RS17195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHA79_RS17200	COG0697	spore germination
KHA79_RS17205	COG1666	GTP binding
KHA79_RS17215	COG1187	pseudouridine synthase activity
KHA79_RS17240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHA79_RS17240	COG2205	protein histidine kinase activity
KHA79_RS17265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHA79_RS17340	COG0842	Transport permease protein
KHA79_RS17345	COG1131	(ABC) transporter
KHA79_RS17350	COG0025	NhaP-type Na H and K H
KHA79_RS17360	COG1573	uracil-dna glycosylase
KHA79_RS17375	COG3384	dioxygenase
KHA79_RS17380	COG0583	DNA-binding transcription factor activity
KHA79_RS17390	COG0667	Aldo Keto reductase
KHA79_RS17400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_RS17405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_RS17430	COG3706	GGDEF domain
KHA79_RS17445	COG5001	Diguanylate cyclase
KHA79_RS17475	COG4106	trans-aconitate 2-methyltransferase activity
KHA79_RS17485	COG2076	Multidrug Resistance protein
KHA79_RS17495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHA79_RS17525	COG3279	Response regulator of the LytR AlgR family
KHA79_RS17530	COG3275	phosphorelay sensor kinase activity
KHA79_RS17535	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KHA79_RS17555	COG0531	amino acid
KHA79_RS17565	COG5297	Belongs to the glycosyl hydrolase family 6
KHA79_RS17565	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHA79_RS17570	COG0612	Peptidase, M16
KHA79_RS17580	COG0741	lytic transglycosylase activity
KHA79_RS17595	COG2207	Transcriptional regulator
KHA79_RS17605	COG0598	Magnesium transport protein CorA
KHA79_RS17610	COG1113	amino acid transport
KHA79_RS17615	COG0697	spore germination
KHA79_RS17630	COG2249	NAD(P)H dehydrogenase (quinone) activity
KHA79_RS17650	COG5520	Belongs to the glycosyl hydrolase 30 family
KHA79_RS17740	COG2131	deaminase
KHA79_RS17760	COG0840	transmembrane signaling receptor activity
KHA79_RS17795	COG2353	YceI-like domain
KHA79_RS17825	COG0584	glycerophosphoryl diester phosphodiesterase
KHA79_RS17835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KHA79_RS17855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHA79_RS17860	COG0459	protein refolding
KHA79_RS17875	COG1324	tolerance protein
KHA79_RS17885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHA79_RS17895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHA79_RS17900	COG0511	ligase activity, forming carbon-carbon bonds
KHA79_RS17905	COG0439	Biotin carboxylase
KHA79_RS17920	COG2264	protein methyltransferase activity
KHA79_RS17940	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KHA79_RS17945	COG4589	Belongs to the CDS family
KHA79_RS17960	COG0138	bifunctional purine biosynthesis protein purh
KHA79_RS17965	COG0151	Belongs to the GarS family
KHA79_RS17970	COG1289	transmembrane transporter activity
KHA79_RS17975	COG2814	Major facilitator Superfamily
KHA79_RS18010	COG2816	NAD+ diphosphatase activity
KHA79_RS18050	COG2906	2 iron, 2 sulfur cluster binding
KHA79_RS18080	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KHA79_RS18095	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KHA79_RS18100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHA79_RS18105	COG0730	response to heat
KHA79_RS18115	COG0134	indole-3-glycerol-phosphate synthase activity
KHA79_RS18120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHA79_RS18140	COG1597	lipid kinase activity
KHA79_RS18155	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KHA79_RS18175	COG2111	Na H antiporter
KHA79_RS18175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KHA79_RS18180	COG1006	Multisubunit Na H antiporter MnhC subunit
KHA79_RS18185	COG0651	ATP synthesis coupled electron transport
KHA79_RS18195	COG2212	antiporter activity
KHA79_RS18200	COG1320	monovalent cation:proton antiporter activity
KHA79_RS18205	COG0530	calcium, potassium:sodium antiporter activity
KHA79_RS18220	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KHA79_RS18225	COG2852	Protein conserved in bacteria
KHA79_RS18245	COG3104	oligopeptide transport
KHA79_RS18250	COG3483	tryptophan 2,3-dioxygenase activity
KHA79_RS18260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHA79_RS18275	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHA79_RS18290	COG0513	Belongs to the DEAD box helicase family
KHA79_RS18310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHA79_RS18320	COG2354	Protein conserved in bacteria
KHA79_RS18340	COG3264	Mechanosensitive ion channel
KHA79_RS18340	COG1196	nuclear chromosome segregation
KHA79_RS18345	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS18345	COG0604	alcohol dehydrogenase
KHA79_RS18345	COG3321	synthase
KHA79_RS18365	COG1595	DNA-templated transcription, initiation
KHA79_RS18380	COG1802	Transcriptional regulator
KHA79_RS18430	COG1414	Transcriptional regulator
KHA79_RS18435	COG0738	Major facilitator superfamily
KHA79_RS18440	COG3254	rhamnose metabolic process
KHA79_RS18445	COG4948	Mandelate Racemase Muconate Lactonizing
KHA79_RS18450	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHA79_RS18455	COG1028	Short-chain dehydrogenase reductase Sdr
KHA79_RS18490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHA79_RS18505	COG4807	Protein conserved in bacteria
KHA79_RS18535	COG1506	peptidase
KHA79_RS18535	COG0823	Involved in the tonB-independent uptake of proteins
KHA79_RS18635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHA79_RS18660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHA79_RS18665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHA79_RS18675	COG0753	catalase activity
KHA79_RS18695	COG1136	(ABC) transporter
KHA79_RS18700	COG0577	efflux transmembrane transporter activity
KHA79_RS18720	COG0697	spore germination
KHA79_RS18725	COG0564	pseudouridine synthase activity
KHA79_RS18745	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHA79_RS18755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHA79_RS18770	COG0318	PFAM AMP-dependent synthetase and ligase
KHA79_RS18775	COG0727	PFAM Uncharacterised protein family (UPF0153)
KHA79_RS18785	COG0596	Alpha beta hydrolase
KHA79_RS18800	COG3177	Filamentation induced by cAMP protein fic
KHA79_RS18805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHA79_RS18815	COG0612	Peptidase, M16
KHA79_RS18825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHA79_RS18960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHA79_RS18970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHA79_RS18975	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KHA79_RS19010	COG0183	Belongs to the thiolase family
KHA79_RS19020	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHA79_RS19025	COG3387	PFAM Glycoside hydrolase 15-related
KHA79_RS19030	COG0745	RESPONSE REGULATOR receiver
KHA79_RS19045	COG1404	Belongs to the peptidase S8 family
KHA79_RS19055	COG3100	YcgL domain-containing protein
KHA79_RS19060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHA79_RS19070	COG0463	Glycosyl transferase, family 2
KHA79_RS19105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHA79_RS19120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHA79_RS19140	COG3179	chitinase
KHA79_RS19170	COG1294	oxidase, subunit
KHA79_RS19175	COG1271	oxidase subunit
KHA79_RS19190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHA79_RS19195	COG0408	coproporphyrinogen oxidase activity
KHA79_RS19205	COG2323	membrane
KHA79_RS19230	COG0589	response to stress
KHA79_RS19245	COG0210	DNA helicase
KHA79_RS19295	COG0463	Glycosyl transferase, family 2
KHA79_RS19310	COG1192	Involved in chromosome partitioning
KHA79_RS19315	COG0357	Ribosomal RNA small subunit methyltransferase G
KHA79_RS19320	COG3540	Alkaline phosphatase
KHA79_RS19325	COG2091	lysine biosynthetic process via aminoadipic acid
KHA79_RS19350	COG0477	Major facilitator Superfamily
KHA79_RS19370	COG1971	Probably functions as a manganese efflux pump
KHA79_RS19375	COG2205	protein histidine kinase activity
KHA79_RS19390	COG3459	Glycosyltransferase 36 associated
KHA79_RS19395	COG2211	Major facilitator Superfamily
KHA79_RS19400	COG3265	gluconokinase activity
KHA79_RS19420	COG2911	Protein conserved in bacteria
KHA79_RS19425	COG0729	surface antigen
KHA79_RS19450	COG3132	Protein of unknown function, DUF480
KHA79_RS19505	COG0284	orotidine-5'-phosphate decarboxylase activity
KHA79_RS19530	COG2937	Belongs to the GPAT DAPAT family
KHA79_RS19555	COG2211	Major facilitator Superfamily
KHA79_RS19565	COG3693	PFAM glycoside hydrolase, family 10
KHA79_RS19575	COG3386	PFAM SMP-30 Gluconolaconase
KHA79_RS19585	COG0246	Mannitol dehydrogenase
KHA79_RS19590	COG1472	Belongs to the glycosyl hydrolase 3 family
KHA79_RS19595	COG3507	Belongs to the glycosyl hydrolase 43 family
KHA79_RS19610	COG2115	Belongs to the xylose isomerase family
KHA79_RS19635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KHA79_RS19645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHA79_RS19655	COG0805	protein transport
KHA79_RS19665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KHA79_RS19665	COG0519	Catalyzes the synthesis of GMP from XMP
KHA79_RS19670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHA79_RS19685	COG0210	DNA helicase
KHA79_RS19690	COG1435	thymidine kinase activity
KHA79_RS19700	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KHA79_RS19710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHA79_RS19725	COG1119	ATPase activity
KHA79_RS19745	COG0594	ribonuclease P activity