locus-tag	class	description
KFS84_RS00010	COG0592	DNA-directed DNA polymerase activity
KFS84_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFS84_RS00020	COG0187	DNA topoisomerase II activity
KFS84_RS00025	COG1266	CAAX protease self-immunity
KFS84_RS00030	COG0501	Belongs to the peptidase M48B family
KFS84_RS00060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFS84_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS84_RS00115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS84_RS00130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS84_RS00135	COG3387	PFAM Glycoside hydrolase 15-related
KFS84_RS00140	COG0745	RESPONSE REGULATOR receiver
KFS84_RS00155	COG1404	Belongs to the peptidase S8 family
KFS84_RS00165	COG3100	YcgL domain-containing protein
KFS84_RS00170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFS84_RS00180	COG0463	Glycosyl transferase, family 2
KFS84_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS00220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFS84_RS00235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS84_RS00250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFS84_RS00260	COG1294	oxidase, subunit
KFS84_RS00265	COG1271	oxidase subunit
KFS84_RS00280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS84_RS00285	COG0408	coproporphyrinogen oxidase activity
KFS84_RS00320	COG2323	membrane
KFS84_RS00330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_RS00330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_RS00350	COG0589	response to stress
KFS84_RS00380	COG0210	DNA helicase
KFS84_RS00450	COG0463	Glycosyl transferase, family 2
KFS84_RS00460	COG1475	DNA binding
KFS84_RS00465	COG1192	Involved in chromosome partitioning
KFS84_RS00470	COG0357	Ribosomal RNA small subunit methyltransferase G
KFS84_RS00475	COG3540	Alkaline phosphatase
KFS84_RS00490	COG2091	lysine biosynthetic process via aminoadipic acid
KFS84_RS00515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS84_RS00580	COG3279	Response regulator of the LytR AlgR family
KFS84_RS00585	COG3275	phosphorelay sensor kinase activity
KFS84_RS00610	COG0531	amino acid
KFS84_RS00620	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_RS00620	COG5297	Belongs to the glycosyl hydrolase family 6
KFS84_RS00625	COG0612	Peptidase, M16
KFS84_RS00655	COG2264	protein methyltransferase activity
KFS84_RS00680	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFS84_RS00700	COG4589	Belongs to the CDS family
KFS84_RS00725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS84_RS00730	COG0138	bifunctional purine biosynthesis protein purh
KFS84_RS00740	COG0151	Belongs to the GarS family
KFS84_RS00765	COG0339	signal peptide processing
KFS84_RS00770	COG0681	Belongs to the peptidase S26 family
KFS84_RS00790	COG0583	DNA-binding transcription factor activity
KFS84_RS00795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KFS84_RS00800	COG2224	Isocitrate lyase
KFS84_RS00805	COG3706	GGDEF domain
KFS84_RS00845	COG0659	secondary active sulfate transmembrane transporter activity
KFS84_RS00875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS84_RS00880	COG2130	NADP-dependent
KFS84_RS00885	COG0667	Aldo Keto reductase
KFS84_RS00895	COG1187	pseudouridine synthase activity
KFS84_RS00915	COG1666	GTP binding
KFS84_RS00920	COG0697	spore germination
KFS84_RS00925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFS84_RS00935	COG0246	Mannitol dehydrogenase
KFS84_RS00965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS84_RS01000	COG0180	Tryptophanyl-tRNA synthetase
KFS84_RS01010	COG3237	CsbD-like
KFS84_RS01040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFS84_RS01045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFS84_RS01045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFS84_RS01095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS84_RS01145	COG2084	Dehydrogenase
KFS84_RS01150	COG1902	pentaerythritol trinitrate reductase activity
KFS84_RS01165	COG2814	Major facilitator Superfamily
KFS84_RS01170	COG0583	DNA-binding transcription factor activity
KFS84_RS01200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS84_RS01205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFS84_RS01210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFS84_RS01225	COG2911	Protein conserved in bacteria
KFS84_RS01230	COG0729	surface antigen
KFS84_RS01250	COG3132	Protein of unknown function, DUF480
KFS84_RS01280	COG0523	cobalamin synthesis protein
KFS84_RS01290	COG1742	UPF0060 membrane protein
KFS84_RS01300	COG3245	cytochrome
KFS84_RS01310	COG1960	acyl-CoA dehydrogenase activity
KFS84_RS01315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFS84_RS01360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFS84_RS01370	COG0697	spore germination
KFS84_RS01385	COG3459	Glycosyltransferase 36 associated
KFS84_RS01415	COG2906	2 iron, 2 sulfur cluster binding
KFS84_RS01420	COG1051	belongs to the nudix hydrolase family
KFS84_RS01445	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFS84_RS01460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFS84_RS01465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS84_RS01470	COG0730	response to heat
KFS84_RS01475	COG4124	Belongs to the glycosyl hydrolase 26 family
KFS84_RS01475	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_RS01485	COG0134	indole-3-glycerol-phosphate synthase activity
KFS84_RS01490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFS84_RS01510	COG1597	lipid kinase activity
KFS84_RS01525	COG0484	heat shock protein binding
KFS84_RS01540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_RS01545	COG2111	Na H antiporter
KFS84_RS01545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFS84_RS01550	COG1006	Multisubunit Na H antiporter MnhC subunit
KFS84_RS01555	COG0651	ATP synthesis coupled electron transport
KFS84_RS01565	COG2212	antiporter activity
KFS84_RS01570	COG1320	monovalent cation:proton antiporter activity
KFS84_RS01580	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KFS84_RS01605	COG2264	protein methyltransferase activity
KFS84_RS01630	COG1971	Probably functions as a manganese efflux pump
KFS84_RS01635	COG2205	protein histidine kinase activity
KFS84_RS01645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS84_RS01685	COG2816	NAD+ diphosphatase activity
KFS84_RS01760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFS84_RS01775	COG5001	Diguanylate cyclase
KFS84_RS01810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_RS01815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS84_RS01825	COG0667	Aldo Keto reductase
KFS84_RS01830	COG0667	Aldo Keto reductase
KFS84_RS01850	COG3384	dioxygenase
KFS84_RS01865	COG1573	uracil-dna glycosylase
KFS84_RS01870	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFS84_RS01880	COG0025	NhaP-type Na H and K H
KFS84_RS01885	COG1131	(ABC) transporter
KFS84_RS01890	COG0842	Transport permease protein
KFS84_RS01930	COG4206	TonB-dependent receptor
KFS84_RS01940	COG1956	GAF domain-containing protein
KFS84_RS01945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFS84_RS01955	COG0720	synthase
KFS84_RS01970	COG0625	glutathione transferase activity
KFS84_RS02000	COG1643	Atp-dependent helicase
KFS84_RS02005	COG0084	hydrolase, TatD family'
KFS84_RS02040	COG0842	Transport permease protein
KFS84_RS02045	COG1131	(ABC) transporter
KFS84_RS02050	COG0543	2 iron, 2 sulfur cluster binding
KFS84_RS02050	COG0633	Ferredoxin
KFS84_RS02060	COG1476	TRANSCRIPTIONal
KFS84_RS02070	COG4555	ABC transporter
KFS84_RS02095	COG0625	glutathione transferase activity
KFS84_RS02200	COG1199	ATP-dependent helicase activity
KFS84_RS02240	COG0628	permease
KFS84_RS02260	COG2133	pyrroloquinoline quinone binding
KFS84_RS02300	COG5463	Belongs to the UPF0441 family
KFS84_RS02305	COG0754	glutathionylspermidine amidase activity
KFS84_RS02380	COG2831	hemolysin activation secretion protein
KFS84_RS02390	COG0714	Associated with various cellular activities
KFS84_RS02425	COG1522	sequence-specific DNA binding
KFS84_RS02430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFS84_RS02445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_RS02450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS84_RS02475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFS84_RS02500	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS02510	COG0156	8-amino-7-oxononanoate synthase activity
KFS84_RS02515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFS84_RS02525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFS84_RS02545	COG2267	carboxylic ester hydrolase activity
KFS84_RS02645	COG2960	long-chain fatty acid transporting porin activity
KFS84_RS02670	COG1166	arginine decarboxylase activity
KFS84_RS02695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_RS02725	COG2205	protein histidine kinase activity
KFS84_RS02725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFS84_RS02800	COG1187	pseudouridine synthase activity
KFS84_RS02860	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KFS84_RS02875	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS84_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS02910	COG3186	Phenylalanine-4-hydroxylase
KFS84_RS02915	COG1522	sequence-specific DNA binding
KFS84_RS02930	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFS84_RS02950	COG0671	phosphoesterase, PA-phosphatase related
KFS84_RS02965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFS84_RS03000	COG1929	Belongs to the glycerate kinase type-1 family
KFS84_RS03010	COG0531	amino acid
KFS84_RS03015	COG4566	intracellular signal transduction
KFS84_RS03020	COG4191	Histidine kinase
KFS84_RS03025	COG1285	pathogenesis
KFS84_RS03040	COG1322	Protein conserved in bacteria
KFS84_RS03055	COG1360	Flagellar Motor Protein
KFS84_RS03090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS84_RS03095	COG1819	glycosyl
KFS84_RS03100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KFS84_RS03100	COG2755	lipolytic protein G-D-S-L family
KFS84_RS03105	COG0583	DNA-binding transcription factor activity
KFS84_RS03125	COG4221	oxidoreductase activity
KFS84_RS03145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFS84_RS03155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS84_RS03170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFS84_RS03180	COG2814	Major facilitator Superfamily
KFS84_RS03195	COG0739	heme binding
KFS84_RS03200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFS84_RS03230	COG2885	chlorophyll binding
KFS84_RS03235	COG1064	alcohol dehydrogenase
KFS84_RS03240	COG2234	aminopeptidase activity
KFS84_RS03250	COG4942	peptidase
KFS84_RS03255	COG0793	Belongs to the peptidase S41A family
KFS84_RS03290	COG0531	amino acid
KFS84_RS03295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFS84_RS03295	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFS84_RS03300	COG1486	melibiose metabolic process
KFS84_RS03320	COG1565	acr, cog1565
KFS84_RS03320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFS84_RS03325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS84_RS03330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KFS84_RS03335	COG1845	cytochrome c oxidase, subunit III
KFS84_RS03360	COG0109	protoheme IX farnesyltransferase activity
KFS84_RS03380	COG0358	DNA primase activity
KFS84_RS03385	COG1295	ribonuclease BN
KFS84_RS03405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFS84_RS03410	COG2308	Evidence 4 Homologs of previously reported genes of
KFS84_RS03425	COG2133	pyrroloquinoline quinone binding
KFS84_RS03465	COG0531	amino acid
KFS84_RS03475	COG4948	Mandelate Racemase Muconate Lactonizing
KFS84_RS03485	COG4771	TonB-dependent receptor
KFS84_RS03540	COG5383	Protein conserved in bacteria
KFS84_RS03565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS84_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_RS03595	COG1652	LysM domain
KFS84_RS03605	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KFS84_RS03610	COG1518	maintenance of DNA repeat elements
KFS84_RS03680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFS84_RS03685	COG3118	belongs to the thioredoxin family
KFS84_RS03695	COG2884	Cell division ATP-binding protein ftsE
KFS84_RS03700	COG2177	Part of the ABC transporter FtsEX involved in
KFS84_RS03705	COG2201	protein-glutamate methylesterase activity
KFS84_RS03710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFS84_RS03715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS84_RS03735	COG1252	NADH dehydrogenase
KFS84_RS03745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFS84_RS03755	COG0534	Mate efflux family protein
KFS84_RS03760	COG0616	signal peptide processing
KFS84_RS03770	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS03810	COG2010	Cytochrome c
KFS84_RS03820	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS84_RS03840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS84_RS03845	COG1077	Cell shape determining protein MreB Mrl
KFS84_RS03850	COG1792	Involved in formation and maintenance of cell shape
KFS84_RS03860	COG0768	penicillin binding
KFS84_RS03865	COG0772	Belongs to the SEDS family
KFS84_RS03880	COG2951	lytic endotransglycosylase activity
KFS84_RS03890	COG1686	Belongs to the peptidase S11 family
KFS84_RS03905	COG0321	lipoyl(octanoyl) transferase activity
KFS84_RS03910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFS84_RS03935	COG1056	cytidyltransferase-related domain
KFS84_RS03935	COG1051	belongs to the nudix hydrolase family
KFS84_RS03990	COG1090	epimerase
KFS84_RS04005	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFS84_RS04015	COG2823	Periplasmic or secreted lipoprotein
KFS84_RS04025	COG2205	protein histidine kinase activity
KFS84_RS04025	COG2202	Pas domain
KFS84_RS04030	COG0784	Response regulator, receiver
KFS84_RS04035	COG4191	Histidine kinase
KFS84_RS04045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFS84_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS04065	COG4305	rare lipoprotein A
KFS84_RS04075	COG3250	beta-galactosidase activity
KFS84_RS04090	COG2188	Transcriptional regulator
KFS84_RS04100	COG1609	Transcriptional regulator
KFS84_RS04105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS84_RS04110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFS84_RS04175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS84_RS04200	COG2207	Transcriptional regulator
KFS84_RS04225	COG2205	protein histidine kinase activity
KFS84_RS04240	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KFS84_RS04245	COG3791	Glutathione-dependent formaldehyde-activating
KFS84_RS04260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS84_RS04270	COG0697	spore germination
KFS84_RS04295	COG1307	EDD domain protein, DegV family
KFS84_RS04310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS84_RS04330	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS84_RS04355	COG0436	Aminotransferase
KFS84_RS04385	COG1162	GTPase activity
KFS84_RS04415	COG2211	Major facilitator Superfamily
KFS84_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS04430	COG2851	Citrate transporter
KFS84_RS04445	COG0642	Histidine kinase
KFS84_RS04485	COG4191	Histidine kinase
KFS84_RS04500	COG1301	dicarboxylic acid transport
KFS84_RS04505	COG0280	phosphate acetyltransferase
KFS84_RS04505	COG0281	malic enzyme
KFS84_RS04565	COG1560	Kdo2-lipid A biosynthetic process
KFS84_RS04570	COG1519	Transferase
KFS84_RS04575	COG1538	Outer membrane efflux protein
KFS84_RS04580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFS84_RS04590	COG3706	GGDEF domain
KFS84_RS04595	COG0473	3-isopropylmalate dehydrogenase activity
KFS84_RS04600	COG0066	3-isopropylmalate dehydratase activity
KFS84_RS04620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFS84_RS04640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFS84_RS04645	COG0840	transmembrane signaling receptor activity
KFS84_RS04675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFS84_RS04685	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFS84_RS04710	COG0563	adenylate kinase activity
KFS84_RS04730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFS84_RS04740	COG0671	phosphoesterase, PA-phosphatase related
KFS84_RS04760	COG1940	carbohydrate kinase activity
KFS84_RS04770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS84_RS04805	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFS84_RS04825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFS84_RS04830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFS84_RS04855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFS84_RS04865	COG0193	aminoacyl-tRNA hydrolase activity
KFS84_RS04870	COG0012	GTP binding
KFS84_RS04890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS84_RS04900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFS84_RS04905	COG0250	Participates in transcription elongation, termination and antitermination
KFS84_RS04910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFS84_RS04925	COG0222	ribosome binding
KFS84_RS04935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFS84_RS04950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFS84_RS04955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFS84_RS04960	COG0051	transcription antitermination factor activity, RNA binding
KFS84_RS04970	COG0088	Forms part of the polypeptide exit tunnel
KFS84_RS04975	COG0089	rRNA binding
KFS84_RS04980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFS84_RS05005	COG0255	Belongs to the universal ribosomal protein uL29 family
KFS84_RS05010	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFS84_RS05020	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFS84_RS05025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFS84_RS05055	COG1841	ribosomal large subunit assembly
KFS84_RS05065	COG0201	protein transport
KFS84_RS05090	COG0203	ribosomal protein L17
KFS84_RS05095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFS84_RS05115	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFS84_RS05140	COG1217	gtp-binding protein TYPA
KFS84_RS05145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFS84_RS05155	COG0039	L-malate dehydrogenase activity
KFS84_RS05170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFS84_RS05180	COG0625	glutathione transferase activity
KFS84_RS05205	COG0584	glycerophosphoryl diester phosphodiesterase
KFS84_RS05235	COG0604	alcohol dehydrogenase
KFS84_RS05240	COG0667	Aldo Keto reductase
KFS84_RS05250	COG2814	Major facilitator Superfamily
KFS84_RS05255	COG0583	DNA-binding transcription factor activity
KFS84_RS05260	COG2885	chlorophyll binding
KFS84_RS05290	COG0156	8-amino-7-oxononanoate synthase activity
KFS84_RS05295	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KFS84_RS05300	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KFS84_RS05305	COG4208	sulfate ABC transporter
KFS84_RS05310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFS84_RS05330	COG0588	phosphoglycerate mutase activity
KFS84_RS05340	COG0285	dihydrofolate synthase activity
KFS84_RS05360	COG2833	Protein of unknown function (DUF455)
KFS84_RS05375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS84_RS05385	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS05390	COG0248	Ppx GppA phosphatase
KFS84_RS05395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFS84_RS05410	COG4783	chaperone-mediated protein folding
KFS84_RS05425	COG0473	3-isopropylmalate dehydrogenase activity
KFS84_RS05485	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFS84_RS05495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFS84_RS05525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS84_RS05535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS84_RS05545	COG0328	RNA-DNA hybrid ribonuclease activity
KFS84_RS05550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS84_RS05555	COG0631	protein serine/threonine phosphatase activity
KFS84_RS05575	COG0859	PFAM glycosyl transferase family 9
KFS84_RS05585	COG1234	tRNA 3'-trailer cleavage
KFS84_RS05590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFS84_RS05600	COG0315	cyclic pyranopterin monophosphate synthase activity
KFS84_RS05605	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFS84_RS05610	COG0314	molybdopterin synthase activity
KFS84_RS05670	COG2003	Belongs to the UPF0758 family
KFS84_RS05765	COG0537	adenosine 5'-monophosphoramidase activity
KFS84_RS05810	COG1399	metal-binding, possibly nucleic acid-binding protein
KFS84_RS05815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFS84_RS05820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS84_RS05825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KFS84_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS05835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS84_RS05845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFS84_RS05850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFS84_RS05855	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFS84_RS05905	COG0587	DNA-directed DNA polymerase activity
KFS84_RS05920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS84_RS05925	COG0372	Belongs to the citrate synthase family
KFS84_RS05950	COG3609	addiction module antidote protein, CC2985 family
KFS84_RS05985	COG2373	Large extracellular alpha-helical protein
KFS84_RS06015	COG4953	penicillin-binding protein 1C
KFS84_RS06035	COG0330	HflC and HflK could
KFS84_RS06040	COG0330	HflC and HflK could
KFS84_RS06045	COG0604	alcohol dehydrogenase
KFS84_RS06065	COG0678	peroxiredoxin activity
KFS84_RS06090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFS84_RS06190	COG3275	phosphorelay sensor kinase activity
KFS84_RS06220	COG0492	ferredoxin-NADP+ reductase activity
KFS84_RS06265	COG3459	Glycosyltransferase 36 associated
KFS84_RS06275	COG1063	alcohol dehydrogenase
KFS84_RS06305	COG0753	catalase activity
KFS84_RS06310	COG5001	Diguanylate cyclase
KFS84_RS06310	COG2203	Gaf domain
KFS84_RS06310	COG3706	GGDEF domain
KFS84_RS06310	COG4251	negative regulation of phosphorylation
KFS84_RS06345	COG2814	Major facilitator Superfamily
KFS84_RS06365	COG2194	sulfuric ester hydrolase activity
KFS84_RS06375	COG0745	RESPONSE REGULATOR receiver
KFS84_RS06380	COG2205	protein histidine kinase activity
KFS84_RS06400	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFS84_RS06405	COG2894	cell division
KFS84_RS06410	COG0850	regulation of cytokinetic process
KFS84_RS06420	COG4585	Histidine kinase
KFS84_RS06445	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFS84_RS06465	COG1216	Glycosyl transferase, family 2
KFS84_RS06470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS84_RS06480	COG1199	ATP-dependent helicase activity
KFS84_RS06500	COG0189	ligase activity
KFS84_RS06575	COG0457	Tetratricopeptide repeat
KFS84_RS06580	COG4771	TonB-dependent receptor
KFS84_RS06585	COG4771	TonB-dependent receptor
KFS84_RS06590	COG0489	protein tyrosine kinase activity
KFS84_RS06595	COG0717	Belongs to the dCTP deaminase family
KFS84_RS06620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS84_RS06635	COG0494	nUDIX hydrolase
KFS84_RS06645	COG0433	COG0433 Predicted ATPase
KFS84_RS06650	COG0741	lytic transglycosylase activity
KFS84_RS06655	COG0688	phosphatidylethanolamine metabolic process
KFS84_RS06665	COG2890	protein-(glutamine-N5) methyltransferase activity
KFS84_RS06700	COG3853	Toxic anion resistance protein (TelA)
KFS84_RS06730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFS84_RS06760	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS84_RS06770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFS84_RS06775	COG0649	NAD binding
KFS84_RS06780	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFS84_RS06785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFS84_RS06790	COG1034	ATP synthesis coupled electron transport
KFS84_RS06825	COG1007	ATP synthesis coupled electron transport
KFS84_RS06840	COG0195	Participates in both transcription termination and antitermination
KFS84_RS06875	COG1185	polyribonucleotide nucleotidyltransferase activity
KFS84_RS06885	COG3300	MHYT domain
KFS84_RS06885	COG5001	Diguanylate cyclase
KFS84_RS06895	COG1201	RNA secondary structure unwinding
KFS84_RS06900	COG0840	transmembrane signaling receptor activity
KFS84_RS06905	COG0840	transmembrane signaling receptor activity
KFS84_RS06910	COG0835	chemotaxis
KFS84_RS06975	COG1194	a g-specific adenine glycosylase
KFS84_RS06980	COG0552	protein localization to endoplasmic reticulum
KFS84_RS06990	COG3938	Belongs to the proline racemase family
KFS84_RS06995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_RS07010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS84_RS07020	COG0006	proline dipeptidase activity
KFS84_RS07035	COG0531	amino acid
KFS84_RS07045	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_RS07055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KFS84_RS07060	COG3858	chitin binding
KFS84_RS07060	COG1388	LysM domain
KFS84_RS07075	COG0837	glucose binding
KFS84_RS07120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFS84_RS07130	COG0494	nUDIX hydrolase
KFS84_RS07135	COG1218	3'(2'),5'-bisphosphate nucleotidase
KFS84_RS07140	COG3956	TIGRFAM MazG family protein
KFS84_RS07145	COG1742	UPF0060 membrane protein
KFS84_RS07150	COG0330	HflC and HflK could
KFS84_RS07185	COG0697	spore germination
KFS84_RS07215	COG2124	cytochrome p450
KFS84_RS07220	COG2124	cytochrome p450
KFS84_RS07225	COG2124	cytochrome p450
KFS84_RS07230	COG1141	Ferredoxin
KFS84_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS07240	COG2124	cytochrome p450
KFS84_RS07245	COG0142	geranyltranstransferase activity
KFS84_RS07250	COG1657	PFAM Prenyltransferase squalene oxidase
KFS84_RS07260	COG1304	FMN binding
KFS84_RS07275	COG1309	transcriptional regulator
KFS84_RS07295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFS84_RS07300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFS84_RS07305	COG0463	Glycosyl transferase, family 2
KFS84_RS07310	COG0517	IMP dehydrogenase activity
KFS84_RS07315	COG2982	Protein involved in outer membrane biogenesis
KFS84_RS07320	COG1272	protein, Hemolysin III
KFS84_RS07325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFS84_RS07330	COG0739	heme binding
KFS84_RS07335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS84_RS07340	COG0626	cystathionine gamma-synthase activity
KFS84_RS07345	COG0460	homoserine dehydrogenase
KFS84_RS07345	COG0527	aspartate kinase activity
KFS84_RS07350	COG2267	carboxylic ester hydrolase activity
KFS84_RS07360	COG1760	l-serine dehydratase
KFS84_RS07375	COG3038	cytochrome b561
KFS84_RS07405	COG0477	Major facilitator Superfamily
KFS84_RS07415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFS84_RS07425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_RS07445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFS84_RS07515	COG0519	Catalyzes the synthesis of GMP from XMP
KFS84_RS07530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFS84_RS07560	COG0840	transmembrane signaling receptor activity
KFS84_RS07570	COG1113	amino acid transport
KFS84_RS07650	COG3507	Belongs to the glycosyl hydrolase 43 family
KFS84_RS07690	COG4771	TonB-dependent receptor
KFS84_RS07700	COG3345	alpha-galactosidase
KFS84_RS07720	COG0742	ribosomal rna small subunit methyltransferase
KFS84_RS07735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFS84_RS07740	COG0405	Gamma-glutamyltransferase
KFS84_RS07760	COG0644	oxidoreductase
KFS84_RS07800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFS84_RS07805	COG3291	Pkd domain containing protein
KFS84_RS07810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFS84_RS07820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFS84_RS07830	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFS84_RS07840	COG1862	Preprotein translocase
KFS84_RS07875	COG3706	GGDEF domain
KFS84_RS07875	COG4251	negative regulation of phosphorylation
KFS84_RS07875	COG5001	Diguanylate cyclase
KFS84_RS07875	COG2203	Gaf domain
KFS84_RS07880	COG1509	lysine 2,3-aminomutase activity
KFS84_RS07890	COG3548	integral membrane protein
KFS84_RS07895	COG0402	S-adenosylhomocysteine deaminase activity
KFS84_RS07930	COG4677	pectinesterase activity
KFS84_RS07940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFS84_RS07995	COG2166	iron-sulfur cluster assembly
KFS84_RS08010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFS84_RS08015	COG0137	argininosuccinate synthase activity
KFS84_RS08020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS84_RS08025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFS84_RS08035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFS84_RS08040	COG0165	Argininosuccinate lyase
KFS84_RS08060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFS84_RS08095	COG1294	oxidase, subunit
KFS84_RS08105	COG4988	ABC transporter
KFS84_RS08110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFS84_RS08140	COG1187	pseudouridine synthase activity
KFS84_RS08165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFS84_RS08190	COG1132	(ABC) transporter
KFS84_RS08260	COG1981	membrane
KFS84_RS08290	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS84_RS08300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFS84_RS08305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_RS08310	COG0750	zinc metalloprotease
KFS84_RS08315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFS84_RS08320	COG0575	Belongs to the CDS family
KFS84_RS08325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFS84_RS08335	COG0528	UMP kinase activity
KFS84_RS08345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFS84_RS08395	COG0024	Methionine aminopeptidase
KFS84_RS08410	COG1393	Belongs to the ArsC family
KFS84_RS08415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFS84_RS08425	COG0367	asparagine synthase
KFS84_RS08465	COG1566	PFAM secretion protein HlyD family protein
KFS84_RS08470	COG2814	Major facilitator Superfamily
KFS84_RS08505	COG0557	exoribonuclease II activity
KFS84_RS08515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS84_RS08535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFS84_RS08555	COG0704	Plays a role in the regulation of phosphate uptake
KFS84_RS08565	COG0581	inorganic phosphate transmembrane transporter activity
KFS84_RS08570	COG0573	inorganic phosphate transmembrane transporter activity
KFS84_RS08575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS84_RS08580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFS84_RS08600	COG0659	secondary active sulfate transmembrane transporter activity
KFS84_RS08650	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_RS08665	COG4535	Mg2 and Co2 transporter CorC
KFS84_RS08680	COG1702	phosphate starvation-inducible protein PhoH
KFS84_RS08695	COG0741	lytic transglycosylase activity
KFS84_RS08700	COG0723	plastoquinol--plastocyanin reductase activity
KFS84_RS08705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFS84_RS08715	COG2857	Cytochrome c1
KFS84_RS08720	COG0625	glutathione transferase activity
KFS84_RS08725	COG2969	positive regulation of protein catabolic process
KFS84_RS08745	COG3844	kynureninase activity
KFS84_RS08760	COG0288	reversible hydration of carbon dioxide
KFS84_RS08810	COG2197	response regulator
KFS84_RS08835	COG0316	Belongs to the HesB IscA family
KFS84_RS08840	COG2977	Belongs to the P-Pant transferase superfamily
KFS84_RS08870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS84_RS08875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFS84_RS08880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFS84_RS08890	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFS84_RS08925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFS84_RS08950	COG1309	transcriptional regulator
KFS84_RS08970	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFS84_RS08990	COG1228	amidohydrolase
KFS84_RS09010	COG4221	oxidoreductase activity
KFS84_RS09055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFS84_RS09060	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFS84_RS09065	COG0077	Prephenate dehydratase
KFS84_RS09065	COG1605	Chorismate mutase
KFS84_RS09095	COG0583	DNA-binding transcription factor activity
KFS84_RS09120	COG1530	ribonuclease E activity
KFS84_RS09135	COG0428	transporter
KFS84_RS09150	COG0316	Belongs to the HesB IscA family
KFS84_RS09150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFS84_RS09170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_RS09190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS84_RS09195	COG2957	Belongs to the agmatine deiminase family
KFS84_RS09205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFS84_RS09210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFS84_RS09215	COG0539	negative regulation of cytoplasmic translation
KFS84_RS09220	COG0776	regulation of translation
KFS84_RS09230	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFS84_RS09235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFS84_RS09245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFS84_RS09250	COG0183	Belongs to the thiolase family
KFS84_RS09255	COG1024	Enoyl-CoA hydratase
KFS84_RS09255	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS84_RS09270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFS84_RS09280	COG1426	Protein conserved in bacteria
KFS84_RS09290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_RS09300	COG0746	molybdenum cofactor guanylyltransferase activity
KFS84_RS09310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFS84_RS09330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFS84_RS09345	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS84_RS09350	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS84_RS09360	COG1914	H( )-stimulated, divalent metal cation uptake system
KFS84_RS09365	COG1321	iron dependent repressor
KFS84_RS09375	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFS84_RS09380	COG0668	transmembrane transport
KFS84_RS09390	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFS84_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS09410	COG1183	phosphatidylcholine synthase activity
KFS84_RS09420	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFS84_RS09440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_RS09440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFS84_RS09450	COG4191	Histidine kinase
KFS84_RS09450	COG0784	Response regulator, receiver
KFS84_RS09455	COG2183	response to ionizing radiation
KFS84_RS09460	COG0784	Response regulator, receiver
KFS84_RS09460	COG2205	protein histidine kinase activity
KFS84_RS09500	COG5002	protein histidine kinase activity
KFS84_RS09500	COG5000	phosphorelay sensor kinase activity
KFS84_RS09545	COG1649	PFAM Uncharacterised BCR, COG1649
KFS84_RS09625	COG1132	(ABC) transporter
KFS84_RS09675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFS84_RS09685	COG2801	Transposase and inactivated derivatives
KFS84_RS09700	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS09705	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS09745	COG2244	polysaccharide biosynthetic process
KFS84_RS09775	COG3038	cytochrome b561
KFS84_RS09795	COG1595	DNA-templated transcription, initiation
KFS84_RS09830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS84_RS09865	COG0038	chloride channel
KFS84_RS09870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFS84_RS09890	COG1674	ftsk spoiiie
KFS84_RS09895	COG0492	ferredoxin-NADP+ reductase activity
KFS84_RS09905	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KFS84_RS09915	COG0542	response to heat
KFS84_RS09935	COG0482	sulfurtransferase activity
KFS84_RS09940	COG2915	High frequency lysogenization protein hflD homolog
KFS84_RS09960	COG1116	anion transmembrane transporter activity
KFS84_RS09975	COG0840	transmembrane signaling receptor activity
KFS84_RS09980	COG0840	transmembrane signaling receptor activity
KFS84_RS09995	COG0835	chemotaxis
KFS84_RS10005	COG0840	transmembrane signaling receptor activity
KFS84_RS10015	COG0840	transmembrane signaling receptor activity
KFS84_RS10075	COG0318	PFAM AMP-dependent synthetase and ligase
KFS84_RS10080	COG1024	Enoyl-CoA hydratase
KFS84_RS10085	COG0784	Response regulator, receiver
KFS84_RS10085	COG2198	Histidine kinase
KFS84_RS10085	COG2205	protein histidine kinase activity
KFS84_RS10105	COG3279	Response regulator of the LytR AlgR family
KFS84_RS10110	COG4676	Protein conserved in bacteria
KFS84_RS10125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFS84_RS10130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFS84_RS10140	COG0505	Belongs to the CarA family
KFS84_RS10180	COG1024	Enoyl-CoA hydratase
KFS84_RS10190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFS84_RS10210	COG1515	deoxyribonuclease V activity
KFS84_RS10235	COG5001	Diguanylate cyclase
KFS84_RS10270	COG1132	(ABC) transporter
KFS84_RS10285	COG1605	Chorismate mutase
KFS84_RS10285	COG0287	Prephenate dehydrogenase
KFS84_RS10305	COG0484	heat shock protein binding
KFS84_RS10310	COG0443	Heat shock 70 kDa protein
KFS84_RS10315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFS84_RS10320	COG1420	regulation of RNA biosynthetic process
KFS84_RS10325	COG0497	DNA recombination
KFS84_RS10330	COG0735	belongs to the Fur family
KFS84_RS10335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_RS10345	COG2867	negative regulation of translational initiation
KFS84_RS10350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFS84_RS10445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_RS10465	COG0583	DNA-binding transcription factor activity
KFS84_RS10480	COG0415	Belongs to the DNA photolyase family
KFS84_RS10485	COG0305	Participates in initiation and elongation during chromosome replication
KFS84_RS10495	COG1960	acyl-CoA dehydrogenase activity
KFS84_RS10525	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFS84_RS10630	COG0386	Belongs to the glutathione peroxidase family
KFS84_RS10640	COG1846	Transcriptional regulator
KFS84_RS10680	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_RS10690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFS84_RS10720	COG0488	(ABC) transporter
KFS84_RS10725	COG0513	Belongs to the DEAD box helicase family
KFS84_RS10750	COG0657	acetylesterase activity
KFS84_RS10765	COG0564	pseudouridine synthase activity
KFS84_RS10770	COG4681	YaeQ
KFS84_RS10775	COG2081	HI0933 family
KFS84_RS10815	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS10840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFS84_RS10845	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS84_RS10850	COG0802	atpase or kinase
KFS84_RS10855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFS84_RS10855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFS84_RS10905	COG1960	acyl-CoA dehydrogenase activity
KFS84_RS10915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFS84_RS10935	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS10945	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS10950	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS10995	COG0072	phenylalanine-tRNA ligase activity
KFS84_RS10995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFS84_RS11000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFS84_RS11005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFS84_RS11015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFS84_RS11040	COG0556	nucleotide-excision repair
KFS84_RS11045	COG4966	pilus assembly protein PilW
KFS84_RS11095	COG3275	phosphorelay sensor kinase activity
KFS84_RS11100	COG1611	Belongs to the LOG family
KFS84_RS11110	COG2095	MarC family integral membrane protein
KFS84_RS11120	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFS84_RS11160	COG2925	Exonuclease
KFS84_RS11200	COG2902	Dehydrogenase
KFS84_RS11210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFS84_RS11215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFS84_RS11220	COG1960	acyl-CoA dehydrogenase activity
KFS84_RS11225	COG2226	methyltransferase
KFS84_RS11230	COG0646	methionine synthase
KFS84_RS11230	COG1410	methionine synthase
KFS84_RS11235	COG0646	methionine synthase
KFS84_RS11235	COG1410	methionine synthase
KFS84_RS11255	COG2900	Belongs to the SlyX family
KFS84_RS11270	COG0386	Belongs to the glutathione peroxidase family
KFS84_RS11280	COG1725	Transcriptional regulator
KFS84_RS11285	COG1131	(ABC) transporter
KFS84_RS11330	COG2850	peptidyl-arginine hydroxylation
KFS84_RS11340	COG0567	Dehydrogenase, E1 component
KFS84_RS11375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFS84_RS11405	COG1024	Enoyl-CoA hydratase
KFS84_RS11425	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFS84_RS11450	COG0277	FAD linked oxidase domain protein
KFS84_RS11455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFS84_RS11470	COG0531	amino acid
KFS84_RS11475	COG0531	amino acid
KFS84_RS11480	COG0235	Class ii aldolase
KFS84_RS11490	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFS84_RS11495	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFS84_RS11515	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFS84_RS11515	COG0140	phosphoribosyl-ATP diphosphatase activity
KFS84_RS11530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFS84_RS11540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFS84_RS11545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFS84_RS11550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFS84_RS11560	COG0124	histidyl-tRNA synthetase
KFS84_RS11565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFS84_RS11575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFS84_RS11585	COG2951	lytic endotransglycosylase activity
KFS84_RS11595	COG0527	aspartate kinase activity
KFS84_RS11595	COG0460	homoserine dehydrogenase
KFS84_RS11610	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_RS11625	COG0167	dihydroorotate dehydrogenase activity
KFS84_RS11630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFS84_RS11660	COG0671	phosphoesterase, PA-phosphatase related
KFS84_RS11675	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KFS84_RS11720	COG0166	Belongs to the GPI family
KFS84_RS11735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFS84_RS11745	COG0617	tRNA 3'-terminal CCA addition
KFS84_RS11765	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFS84_RS11775	COG0477	Major facilitator Superfamily
KFS84_RS11780	COG2115	Belongs to the xylose isomerase family
KFS84_RS11785	COG1070	Carbohydrate kinase
KFS84_RS11795	COG1501	Belongs to the glycosyl hydrolase 31 family
KFS84_RS11815	COG0800	Aldolase
KFS84_RS11830	COG3734	2-keto-3-deoxy-galactonokinase
KFS84_RS11835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFS84_RS11845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFS84_RS11855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFS84_RS11860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFS84_RS11875	COG0352	thiamine-phosphate diphosphorylase activity
KFS84_RS11875	COG0351	phosphomethylpyrimidine kinase
KFS84_RS11895	COG0583	DNA-binding transcription factor activity
KFS84_RS11900	COG1741	Belongs to the pirin family
KFS84_RS11925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFS84_RS11935	COG2137	regulation of response to DNA damage stimulus
KFS84_RS11940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFS84_RS11945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFS84_RS11950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFS84_RS11955	COG1546	Belongs to the CinA family
KFS84_RS11960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFS84_RS11975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFS84_RS11980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFS84_RS11985	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFS84_RS11990	COG1534	Rna-binding protein
KFS84_RS12005	COG1238	metal cluster binding
KFS84_RS12015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFS84_RS12030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFS84_RS12035	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFS84_RS12040	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFS84_RS12050	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFS84_RS12090	COG1253	flavin adenine dinucleotide binding
KFS84_RS12105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFS84_RS12145	COG0069	glutamate synthase activity
KFS84_RS12150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFS84_RS12160	COG1609	Transcriptional regulator
KFS84_RS12165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS84_RS12165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS84_RS12170	COG1105	Belongs to the carbohydrate kinase PfkB family
KFS84_RS12175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS84_RS12175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFS84_RS12205	COG1136	(ABC) transporter
KFS84_RS12205	COG0577	efflux transmembrane transporter activity
KFS84_RS12255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFS84_RS12265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFS84_RS12270	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KFS84_RS12280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS84_RS12290	COG0348	domain, Protein
KFS84_RS12325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFS84_RS12340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFS84_RS12350	COG1663	tetraacyldisaccharide 4'-kinase activity
KFS84_RS12355	COG1132	(ABC) transporter
KFS84_RS12360	COG0848	biopolymer transport protein
KFS84_RS12365	COG0811	peptide transport
KFS84_RS12405	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFS84_RS12415	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KFS84_RS12430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFS84_RS12435	COG2009	succinate dehydrogenase
KFS84_RS12445	COG0354	folic acid binding
KFS84_RS12450	COG3842	ATPase activity
KFS84_RS12455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFS84_RS12470	COG0129	dihydroxy-acid dehydratase activity
KFS84_RS12475	COG0800	Aldolase
KFS84_RS12490	COG0395	ABC-type sugar transport system, permease component
KFS84_RS12525	COG2350	Protein conserved in bacteria
KFS84_RS12530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFS84_RS12535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFS84_RS12540	COG1187	pseudouridine synthase activity
KFS84_RS12575	COG0436	Aminotransferase
KFS84_RS12580	COG4133	protoheme IX ABC transporter activity
KFS84_RS12630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFS84_RS12745	COG0735	belongs to the Fur family
KFS84_RS12775	COG4452	Inner membrane protein CreD
KFS84_RS12810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFS84_RS12830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFS84_RS12840	COG2198	Histidine kinase
KFS84_RS12840	COG0643	Histidine kinase
KFS84_RS12845	COG0840	transmembrane signaling receptor activity
KFS84_RS12850	COG0840	transmembrane signaling receptor activity
KFS84_RS12855	COG0840	transmembrane signaling receptor activity
KFS84_RS12860	COG0835	chemotaxis
KFS84_RS12865	COG5001	Diguanylate cyclase
KFS84_RS12865	COG4251	negative regulation of phosphorylation
KFS84_RS12865	COG3706	GGDEF domain
KFS84_RS12865	COG2203	Gaf domain
KFS84_RS12895	COG2211	Major facilitator Superfamily
KFS84_RS12915	COG1515	deoxyribonuclease V activity
KFS84_RS12935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS84_RS12960	COG1297	OPT oligopeptide transporter protein
KFS84_RS12985	COG3550	peptidyl-serine autophosphorylation
KFS84_RS12990	COG0629	single-stranded DNA binding
KFS84_RS12995	COG0142	geranyltranstransferase activity
KFS84_RS13020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFS84_RS13035	COG0527	aspartate kinase activity
KFS84_RS13040	COG0384	phenazine biosynthesis protein PhzF
KFS84_RS13050	COG1764	response to oxidative stress
KFS84_RS13065	COG0739	heme binding
KFS84_RS13085	COG0693	protein deglycase activity
KFS84_RS13100	COG0719	Fe-S assembly protein
KFS84_RS13105	COG0396	ATPase activity
KFS84_RS13110	COG0719	Fe-S assembly protein
KFS84_RS13115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFS84_RS13125	COG2146	nitrite reductase [NAD(P)H] activity
KFS84_RS13130	COG4774	siderophore transport
KFS84_RS13155	COG1477	protein flavinylation
KFS84_RS13160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS84_RS13180	COG1555	photosystem II stabilization
KFS84_RS13195	COG3178	'Phosphotransferase
KFS84_RS13200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFS84_RS13210	COG0628	permease
KFS84_RS13230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFS84_RS13280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFS84_RS13295	COG1137	ATPase activity
KFS84_RS13310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS84_RS13320	COG1660	Displays ATPase and GTPase activities
KFS84_RS13330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFS84_RS13335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFS84_RS13340	COG2239	Acts as a magnesium transporter
KFS84_RS13390	COG2801	Transposase and inactivated derivatives
KFS84_RS13420	COG3590	peptidase
KFS84_RS13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFS84_RS13480	COG2311	Membrane
KFS84_RS13485	COG1047	Peptidyl-prolyl cis-trans
KFS84_RS13490	COG0791	NLP P60 protein
KFS84_RS13495	COG0791	NLP P60 protein
KFS84_RS13500	COG1607	acyl-coa hydrolase
KFS84_RS13510	COG1301	dicarboxylic acid transport
KFS84_RS13515	COG1785	Belongs to the alkaline phosphatase family
KFS84_RS13530	COG1722	exodeoxyribonuclease VII activity
KFS84_RS13535	COG0142	geranyltranstransferase activity
KFS84_RS13545	COG4104	PAAR repeat-containing protein
KFS84_RS13565	COG0312	modulator of DNA gyrase
KFS84_RS13575	COG0312	modulator of DNA gyrase
KFS84_RS13595	COG2968	Membrane
KFS84_RS13630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFS84_RS13645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFS84_RS13660	COG0495	leucyl-tRNA aminoacylation
KFS84_RS13670	COG3118	belongs to the thioredoxin family
KFS84_RS13685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFS84_RS13695	COG2040	homocysteine
KFS84_RS13700	COG0833	amino acid
KFS84_RS13710	COG0346	lactoylglutathione lyase activity
KFS84_RS13740	COG2878	Part of a membrane complex involved in electron transport
KFS84_RS13755	COG1595	DNA-templated transcription, initiation
KFS84_RS13780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFS84_RS13800	COG0251	oxidation-reduction process
KFS84_RS13810	COG0392	lysyltransferase activity
KFS84_RS13810	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFS84_RS13840	COG2814	Major facilitator Superfamily
KFS84_RS13845	COG1902	pentaerythritol trinitrate reductase activity
KFS84_RS13850	COG2824	Alkylphosphonate utilization operon protein PhnA
KFS84_RS13855	COG1047	Peptidyl-prolyl cis-trans
KFS84_RS13860	COG1077	Cell shape determining protein MreB Mrl
KFS84_RS13895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFS84_RS13905	COG1451	nucleotide metabolic process
KFS84_RS13925	COG2205	protein histidine kinase activity
KFS84_RS13925	COG2198	Histidine kinase
KFS84_RS13925	COG0784	Response regulator, receiver
KFS84_RS13935	COG2186	Transcriptional regulator
KFS84_RS13940	COG3250	beta-galactosidase activity
KFS84_RS13990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS84_RS13990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFS84_RS13990	COG1703	isobutyryl-CoA mutase activity
KFS84_RS14015	COG0183	Belongs to the thiolase family
KFS84_RS14060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS84_RS14060	COG1793	dna ligase
KFS84_RS14065	COG1793	dna ligase
KFS84_RS14065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFS84_RS14070	COG1201	RNA secondary structure unwinding
KFS84_RS14080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS84_RS14085	COG1278	Cold shock
KFS84_RS14090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFS84_RS14095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFS84_RS14100	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_RS14105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KFS84_RS14110	COG2954	triphosphatase activity
KFS84_RS14120	COG2204	response regulator
KFS84_RS14125	COG1381	Involved in DNA repair and RecF pathway recombination
KFS84_RS14130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFS84_RS14145	COG0681	Belongs to the peptidase S26 family
KFS84_RS14150	COG0481	GTPase activity
KFS84_RS14155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFS84_RS14170	COG1024	Enoyl-CoA hydratase
KFS84_RS14170	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFS84_RS14200	COG2855	membrane
KFS84_RS14215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFS84_RS14245	COG0534	Mate efflux family protein
KFS84_RS14250	COG0335	large ribosomal subunit rRNA binding
KFS84_RS14260	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFS84_RS14265	COG0228	four-way junction DNA binding
KFS84_RS14275	COG2070	2-Nitropropane dioxygenase
KFS84_RS14280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFS84_RS14315	COG0475	glutathione-regulated potassium exporter activity
KFS84_RS14330	COG0625	glutathione transferase activity
KFS84_RS14335	COG1082	Xylose isomerase domain protein TIM barrel
KFS84_RS14345	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS84_RS14350	COG1172	Belongs to the binding-protein-dependent transport system permease family
KFS84_RS14355	COG1129	ABC transporter
KFS84_RS14360	COG1879	ABC-type sugar transport system periplasmic component
KFS84_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_RS14385	COG0129	dihydroxy-acid dehydratase activity
KFS84_RS14410	COG2207	Transcriptional regulator
KFS84_RS14435	COG1317	bacterial-type flagellum organization
KFS84_RS14460	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFS84_RS14485	COG4794	Type iii secretion
KFS84_RS14520	COG0745	RESPONSE REGULATOR receiver
KFS84_RS14585	COG3152	Membrane
KFS84_RS14595	COG0156	8-amino-7-oxononanoate synthase activity
KFS84_RS14615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFS84_RS14620	COG1845	cytochrome c oxidase, subunit III
KFS84_RS14625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFS84_RS14650	COG1132	(ABC) transporter
KFS84_RS14685	COG5001	Diguanylate cyclase
KFS84_RS14710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFS84_RS14725	COG0196	riboflavin kinase activity
KFS84_RS14730	COG0728	peptidoglycan biosynthetic process
KFS84_RS14740	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFS84_RS14745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFS84_RS14750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFS84_RS14755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFS84_RS14760	COG0824	Thioesterase
KFS84_RS14770	COG1024	Enoyl-CoA hydratase
KFS84_RS14775	COG1946	Acyl-CoA thioesterase
KFS84_RS14860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS84_RS14905	COG1643	Atp-dependent helicase
KFS84_RS14910	COG0783	Belongs to the Dps family
KFS84_RS14920	COG0514	ATP-dependent DNA helicase (RecQ)
KFS84_RS14950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFS84_RS14955	COG0602	queuosine metabolic process
KFS84_RS14960	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KFS84_RS14965	COG2885	chlorophyll binding
KFS84_RS14980	COG0848	biopolymer transport protein
KFS84_RS14990	COG0824	Thioesterase
KFS84_RS14995	COG2255	four-way junction helicase activity
KFS84_RS15000	COG3158	transport of potassium into the cell
KFS84_RS15005	COG0632	four-way junction helicase activity
KFS84_RS15015	COG0217	transcriptional regulatory protein
KFS84_RS15075	COG0657	acetylesterase activity
KFS84_RS15075	COG2755	lipolytic protein G-D-S-L family
KFS84_RS15100	COG0488	(ABC) transporter
KFS84_RS15145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFS84_RS15145	COG4651	solute:proton antiporter activity
KFS84_RS15155	COG4772	TonB-dependent receptor
KFS84_RS15165	COG4264	IucA IucC family
KFS84_RS15170	COG2814	Major facilitator Superfamily
KFS84_RS15175	COG4264	IucA IucC family
KFS84_RS15180	COG0019	diaminopimelate decarboxylase activity
KFS84_RS15205	COG0542	response to heat
KFS84_RS15230	COG0454	-acetyltransferase
KFS84_RS15250	COG1877	trehalose-phosphatase activity
KFS84_RS15255	COG3387	PFAM Glycoside hydrolase 15-related
KFS84_RS15270	COG4993	Dehydrogenase
KFS84_RS15280	COG0840	transmembrane signaling receptor activity
KFS84_RS15290	COG0564	pseudouridine synthase activity
KFS84_RS15295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFS84_RS15305	COG1125	glycine betaine transport
KFS84_RS15310	COG1174	glycine betaine transport
KFS84_RS15325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFS84_RS15340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFS84_RS15340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFS84_RS15350	COG4993	Dehydrogenase
KFS84_RS15375	COG3657	addiction module killer protein
KFS84_RS15380	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFS84_RS15430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFS84_RS15445	COG0745	RESPONSE REGULATOR receiver
KFS84_RS15455	COG0189	ligase activity
KFS84_RS15510	COG2022	thiamine diphosphate biosynthetic process
KFS84_RS15520	COG0471	metal ion transport
KFS84_RS15520	COG3273	potassium ion transport
KFS84_RS15535	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFS84_RS15550	COG1609	Transcriptional regulator
KFS84_RS15565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFS84_RS15575	COG1115	amino acid carrier protein
KFS84_RS15595	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS15605	COG0840	transmembrane signaling receptor activity
KFS84_RS15610	COG2895	sulfate adenylyltransferase (ATP) activity
KFS84_RS15610	COG0529	Catalyzes the synthesis of activated sulfate
KFS84_RS15620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFS84_RS15625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS84_RS15630	COG0175	sulfate reduction
KFS84_RS15660	COG1393	Belongs to the ArsC family
KFS84_RS15665	COG2198	Histidine kinase
KFS84_RS15665	COG0784	Response regulator, receiver
KFS84_RS15665	COG2205	protein histidine kinase activity
KFS84_RS15685	COG1648	precorrin-2 dehydrogenase activity
KFS84_RS15685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS84_RS15715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KFS84_RS15725	COG2351	hydroxyisourate hydrolase activity
KFS84_RS15730	COG2072	flavoprotein involved in K transport
KFS84_RS15750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFS84_RS15795	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFS84_RS15805	COG3588	fructose-bisphosphate aldolase
KFS84_RS15810	COG0469	pyruvate kinase activity
KFS84_RS15855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFS84_RS15860	COG3047	cAMP biosynthetic process
KFS84_RS15880	COG0640	Transcriptional regulator
KFS84_RS15890	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFS84_RS15895	COG4149	molybdate abc transporter
KFS84_RS15900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFS84_RS15940	COG1376	ErfK ybiS ycfS ynhG family protein
KFS84_RS15945	COG0739	heme binding
KFS84_RS15975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFS84_RS16010	COG0714	Associated with various cellular activities
KFS84_RS16040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KFS84_RS16065	COG0372	Belongs to the citrate synthase family
KFS84_RS16070	COG0254	rRNA binding
KFS84_RS16085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFS84_RS16110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFS84_RS16115	COG1758	RNA polymerase activity
KFS84_RS16120	COG0194	GDP metabolic process
KFS84_RS16125	COG1561	YicC-like family, N-terminal region
KFS84_RS16130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFS84_RS16135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFS84_RS16140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFS84_RS16165	COG1289	transmembrane transporter activity
KFS84_RS16170	COG2814	Major facilitator Superfamily
KFS84_RS16190	COG0006	proline dipeptidase activity
KFS84_RS16195	COG3079	Belongs to the UPF0149 family
KFS84_RS16220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFS84_RS16230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFS84_RS16245	COG1773	rubredoxin
KFS84_RS16260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFS84_RS16280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS84_RS16285	COG1295	ribonuclease BN
KFS84_RS16305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFS84_RS16310	COG1404	Belongs to the peptidase S8 family
KFS84_RS16315	COG1404	Belongs to the peptidase S8 family
KFS84_RS16320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFS84_RS16395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_RS16395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFS84_RS16440	COG3634	alkyl hydroperoxide reductase activity
KFS84_RS16445	COG0583	DNA-binding transcription factor activity
KFS84_RS16475	COG2197	response regulator
KFS84_RS16500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFS84_RS16505	COG0697	spore germination
KFS84_RS16565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS84_RS16570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFS84_RS16580	COG2096	Adenosyltransferase
KFS84_RS16590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KFS84_RS16595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFS84_RS16600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFS84_RS16610	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFS84_RS16615	COG2967	ApaG domain
KFS84_RS16620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFS84_RS16655	COG1704	LemA family
KFS84_RS16660	COG0861	Integral membrane protein TerC family
KFS84_RS16665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFS84_RS16675	COG0642	Histidine kinase
KFS84_RS16690	COG4181	ATPase activity
KFS84_RS16695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KFS84_RS16725	COG0667	Aldo Keto reductase
KFS84_RS16730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFS84_RS16750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFS84_RS16770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFS84_RS16845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFS84_RS16860	COG0494	nUDIX hydrolase
KFS84_RS16875	COG0739	heme binding
KFS84_RS16885	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFS84_RS16890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFS84_RS16900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFS84_RS16905	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS84_RS16930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFS84_RS16945	COG3116	cell division
KFS84_RS16950	COG0275	rRNA processing
KFS84_RS16955	COG2001	Belongs to the MraZ family
KFS84_RS16990	COG0277	FAD linked oxidase domain protein
KFS84_RS17000	COG0745	RESPONSE REGULATOR receiver
KFS84_RS17005	COG2205	protein histidine kinase activity
KFS84_RS17015	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFS84_RS17020	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFS84_RS17045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFS84_RS17050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS84_RS17055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFS84_RS17070	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS84_RS17070	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFS84_RS17080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFS84_RS17110	COG0488	(ABC) transporter
KFS84_RS17115	COG0242	peptide deformylase activity
KFS84_RS17125	COG1960	acyl-CoA dehydrogenase activity
KFS84_RS17135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFS84_RS17145	COG1696	Membrane protein involved in D-alanine export
KFS84_RS17165	COG1215	transferase activity, transferring glycosyl groups
KFS84_RS17175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFS84_RS17255	COG2188	Transcriptional regulator
KFS84_RS17275	COG1450	Type ii and iii secretion system protein
KFS84_RS17290	COG3166	PFAM Fimbrial assembly family protein
KFS84_RS17295	COG3156	type II secretion system protein K
KFS84_RS17300	COG4795	General secretion pathway protein
KFS84_RS17305	COG2165	general secretion pathway protein
KFS84_RS17310	COG4970	Tfp pilus assembly protein FimT
KFS84_RS17315	COG2165	general secretion pathway protein
KFS84_RS17320	COG1459	type II secretion system
KFS84_RS17325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS84_RS17330	COG1404	Belongs to the peptidase S8 family
KFS84_RS17335	COG5295	Hep Hag repeat protein
KFS84_RS17350	COG0047	phosphoribosylformylglycinamidine synthase activity
KFS84_RS17350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFS84_RS17355	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFS84_RS17360	COG4974	Belongs to the 'phage' integrase family
KFS84_RS17385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS84_RS17395	COG0525	valine-tRNA ligase activity
KFS84_RS17425	COG1183	phosphatidylcholine synthase activity
KFS84_RS17435	COG0442	prolyl-tRNA aminoacylation
KFS84_RS17450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS84_RS17455	COG1127	ABC transporter
KFS84_RS17460	COG3218	ABC-type transport auxiliary lipoprotein component
KFS84_RS17460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS84_RS17490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFS84_RS17495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFS84_RS17500	COG0662	Cupin 2, conserved barrel domain protein
KFS84_RS17500	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFS84_RS17525	COG2086	electron transfer activity
KFS84_RS17545	COG0277	FAD linked oxidase domain protein
KFS84_RS17550	COG0300	oxidoreductase activity
KFS84_RS17555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_RS17575	COG0493	'glutamate synthase
KFS84_RS17625	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS17625	COG1216	Glycosyl transferase, family 2
KFS84_RS17630	COG0438	transferase activity, transferring glycosyl groups
KFS84_RS17630	COG1216	Glycosyl transferase, family 2
KFS84_RS17650	COG0626	cystathionine gamma-synthase activity
KFS84_RS17710	COG0596	Alpha beta hydrolase
KFS84_RS17710	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS84_RS17715	COG0308	aminopeptidase N
KFS84_RS17720	COG2226	methyltransferase
KFS84_RS17785	COG2832	Protein of unknown function (DUF454)
KFS84_RS17800	COG0436	Aminotransferase
KFS84_RS17805	COG1505	serine-type exopeptidase activity
KFS84_RS17820	COG1733	regulation of RNA biosynthetic process
KFS84_RS17870	COG0181	hydroxymethylbilane synthase activity
KFS84_RS17895	COG0745	RESPONSE REGULATOR receiver
KFS84_RS17915	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFS84_RS17950	COG0243	molybdopterin cofactor binding
KFS84_RS17955	COG2146	nitrite reductase [NAD(P)H] activity
KFS84_RS17960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFS84_RS17965	COG2223	nitrite transmembrane transporter activity
KFS84_RS17970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFS84_RS17970	COG1116	anion transmembrane transporter activity
KFS84_RS17980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFS84_RS17980	COG1648	precorrin-2 dehydrogenase activity
KFS84_RS18000	COG2204	response regulator
KFS84_RS18005	COG4191	Histidine kinase
KFS84_RS18010	COG0028	Belongs to the TPP enzyme family
KFS84_RS18025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFS84_RS18040	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KFS84_RS18050	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS18055	COG0840	transmembrane signaling receptor activity
KFS84_RS18095	COG1309	transcriptional regulator
KFS84_RS18155	COG1487	ribonuclease activity
KFS84_RS18185	COG0366	Alpha amylase catalytic
KFS84_RS18190	COG0366	Alpha amylase catalytic
KFS84_RS18200	COG1609	Transcriptional regulator
KFS84_RS18215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFS84_RS18220	COG1490	D-aminoacyl-tRNA deacylase activity
KFS84_RS18235	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFS84_RS18255	COG1215	transferase activity, transferring glycosyl groups
KFS84_RS18270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFS84_RS18275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFS84_RS18275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFS84_RS18280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFS84_RS18285	COG0242	peptide deformylase activity
KFS84_RS18290	COG1652	LysM domain
KFS84_RS18295	COG0758	DNA mediated transformation
KFS84_RS18310	COG1714	RDD family
KFS84_RS18315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFS84_RS18315	COG1754	DNA topoisomerase type I activity
KFS84_RS18320	COG0009	L-threonylcarbamoyladenylate synthase
KFS84_RS18345	COG4771	TonB-dependent receptor
KFS84_RS18365	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFS84_RS18410	COG1999	signal sequence binding
KFS84_RS18430	COG4774	siderophore transport
KFS84_RS18475	COG1280	lysine exporter protein (LysE YggA)
KFS84_RS18530	COG1012	belongs to the aldehyde dehydrogenase family
KFS84_RS18595	COG0530	calcium, potassium:sodium antiporter activity
KFS84_RS18610	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFS84_RS18630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_RS18635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KFS84_RS18680	COG3135	benzoate transporter
KFS84_RS18705	COG2951	lytic endotransglycosylase activity
KFS84_RS18725	COG0730	response to heat
KFS84_RS18750	COG0302	gtp cyclohydrolase
KFS84_RS18755	COG0477	Major facilitator Superfamily
KFS84_RS18845	COG0537	adenosine 5'-monophosphoramidase activity
KFS84_RS18865	COG1074	ATP-dependent DNA helicase activity
KFS84_RS18870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFS84_RS18875	COG1127	ABC transporter
KFS84_RS18880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFS84_RS18885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFS84_RS18900	COG2853	Lipoprotein
KFS84_RS18910	COG0546	phosphoglycolate phosphatase activity
KFS84_RS18935	COG0339	signal peptide processing
KFS84_RS18940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFS84_RS18950	COG2217	Heavy metal translocating P-type atpase
KFS84_RS18965	COG2132	Multicopper oxidase
KFS84_RS18990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFS84_RS19005	COG1136	(ABC) transporter
KFS84_RS19015	COG0577	efflux transmembrane transporter activity
KFS84_RS19025	COG0577	efflux transmembrane transporter activity
KFS84_RS19025	COG1136	(ABC) transporter
KFS84_RS19080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFS84_RS19095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFS84_RS19110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFS84_RS19120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFS84_RS19130	COG0356	it plays a direct role in the translocation of protons across the membrane
KFS84_RS19145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFS84_RS19150	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFS84_RS19185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFS84_RS19190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFS84_RS19235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFS84_RS19250	COG4807	Protein conserved in bacteria
KFS84_RS19260	COG1418	mRNA catabolic process
KFS84_RS19275	COG4773	Receptor
KFS84_RS19290	COG0412	Dienelactone hydrolase
KFS84_RS19350	COG0284	orotidine-5'-phosphate decarboxylase activity
KFS84_RS19380	COG1609	Transcriptional regulator
KFS84_RS19390	COG2937	Belongs to the GPAT DAPAT family
KFS84_RS19415	COG2211	Major facilitator Superfamily
KFS84_RS19430	COG3693	PFAM glycoside hydrolase, family 10
KFS84_RS19450	COG3386	PFAM SMP-30 Gluconolaconase
KFS84_RS19530	COG0583	DNA-binding transcription factor activity
KFS84_RS19550	COG0697	spore germination
KFS84_RS19560	COG1113	amino acid transport
KFS84_RS19565	COG0598	Magnesium transport protein CorA
KFS84_RS19575	COG2207	Transcriptional regulator
KFS84_RS19580	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
KFS84_RS19625	COG1472	Belongs to the glycosyl hydrolase 3 family
KFS84_RS19635	COG4948	Mandelate Racemase Muconate Lactonizing
KFS84_RS19645	COG3661	Belongs to the glycosyl hydrolase 67 family
KFS84_RS19655	COG2115	Belongs to the xylose isomerase family
KFS84_RS19660	COG0037	tRNA processing
KFS84_RS19690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFS84_RS19700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFS84_RS19710	COG0805	protein transport
KFS84_RS19720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFS84_RS19720	COG0519	Catalyzes the synthesis of GMP from XMP
KFS84_RS19725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFS84_RS19805	COG0270	DNA (cytosine-5-)-methyltransferase activity
KFS84_RS19815	COG0840	transmembrane signaling receptor activity
KFS84_RS19850	COG2353	YceI-like domain
KFS84_RS19895	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KFS84_RS19920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFS84_RS19925	COG0459	protein refolding
KFS84_RS19940	COG1324	tolerance protein
KFS84_RS19950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFS84_RS19965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFS84_RS19970	COG0511	ligase activity, forming carbon-carbon bonds
KFS84_RS19975	COG0439	Biotin carboxylase
KFS84_RS19995	COG0564	pseudouridine synthase activity
KFS84_RS20025	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFS84_RS20035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFS84_RS20055	COG0318	PFAM AMP-dependent synthetase and ligase
KFS84_RS20060	COG0727	PFAM Uncharacterised protein family (UPF0153)
KFS84_RS20070	COG0596	Alpha beta hydrolase
KFS84_RS20080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFS84_RS20090	COG0612	Peptidase, M16
KFS84_RS20100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFS84_RS20110	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFS84_RS20115	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFS84_RS20155	COG0183	Belongs to the thiolase family
KFS84_RS20170	COG2032	superoxide dismutase activity
KFS84_RS20175	COG2032	superoxide dismutase activity
KFS84_RS20180	COG2204	response regulator
KFS84_RS20185	COG3852	Histidine kinase
KFS84_RS20190	COG0004	ammonium transporteR
KFS84_RS20195	COG0347	Belongs to the P(II) protein family
KFS84_RS20200	COG0174	glutamine synthetase
KFS84_RS20205	COG1968	undecaprenyl-diphosphatase activity
KFS84_RS20225	COG2267	carboxylic ester hydrolase activity
KFS84_RS20235	COG2050	protein possibly involved in aromatic compounds catabolism
KFS84_RS20240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFS84_RS20250	COG2062	phosphohistidine phosphatase, SixA
KFS84_RS20255	COG1192	Involved in chromosome partitioning
KFS84_RS20305	COG2271	Major facilitator Superfamily
KFS84_RS20350	COG1205	dead DEAH box helicase
KFS84_RS20350	COG1111	helicase
KFS84_RS20405	COG0067	glutamate synthase
KFS84_RS20405	COG0069	glutamate synthase activity
KFS84_RS20405	COG0070	glutamate synthase
KFS84_RS20410	COG0493	'glutamate synthase
KFS84_RS20425	COG3104	oligopeptide transport
KFS84_RS20440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFS84_RS20495	COG0513	Belongs to the DEAD box helicase family
KFS84_RS20520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFS84_RS20530	COG2354	Protein conserved in bacteria
KFS84_RS20555	COG3264	Mechanosensitive ion channel
KFS84_RS20555	COG1196	nuclear chromosome segregation
KFS84_RS20560	COG0604	alcohol dehydrogenase
KFS84_RS20560	COG3321	synthase
KFS84_RS20560	COG1028	Short-chain dehydrogenase reductase Sdr
KFS84_RS20595	COG1011	Hydrolase
KFS84_RS20630	COG0577	efflux transmembrane transporter activity
KFS84_RS20635	COG1136	(ABC) transporter
KFS84_RS20645	COG1131	(ABC) transporter
KFS84_RS20660	COG4585	Histidine kinase
KFS84_RS20670	COG2197	response regulator
KFS84_RS20680	COG0753	catalase activity
KFS84_RS20690	COG1304	FMN binding
KFS84_RS20695	COG2186	Transcriptional regulator
KFS84_RS20730	COG0210	DNA helicase
KFS84_RS20735	COG1435	thymidine kinase activity
KFS84_RS20750	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFS84_RS20760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFS84_RS20790	COG0706	membrane insertase activity
KFS84_RS20795	COG0594	ribonuclease P activity