locus-tag	class	description
KM547_RS00010	COG0592	DNA-directed DNA polymerase activity
KM547_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KM547_RS00020	COG0187	DNA topoisomerase II activity
KM547_RS00025	COG1266	CAAX protease self-immunity
KM547_RS00030	COG0501	Belongs to the peptidase M48B family
KM547_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM547_RS00085	COG1280	lysine exporter protein (LysE YggA)
KM547_RS00105	COG4772	TonB-dependent receptor
KM547_RS00120	COG1012	belongs to the aldehyde dehydrogenase family
KM547_RS00155	COG1304	FMN binding
KM547_RS00160	COG2186	Transcriptional regulator
KM547_RS00180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM547_RS00230	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM547_RS00255	COG4771	TonB-dependent receptor
KM547_RS00285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KM547_RS00300	COG3507	Belongs to the glycosyl hydrolase 43 family
KM547_RS00305	COG1609	Transcriptional regulator
KM547_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS00335	COG3186	Phenylalanine-4-hydroxylase
KM547_RS00340	COG1522	sequence-specific DNA binding
KM547_RS00345	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM547_RS00360	COG0671	phosphoesterase, PA-phosphatase related
KM547_RS00370	COG0861	Integral membrane protein TerC family
KM547_RS00375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM547_RS00405	COG1522	sequence-specific DNA binding
KM547_RS00410	COG4771	TonB-dependent receptor
KM547_RS00415	COG0531	amino acid
KM547_RS00420	COG0154	amidase activity
KM547_RS00505	COG0477	Major facilitator Superfamily
KM547_RS00510	COG0302	gtp cyclohydrolase
KM547_RS00535	COG0730	response to heat
KM547_RS00550	COG3706	GGDEF domain
KM547_RS00555	COG2951	lytic endotransglycosylase activity
KM547_RS00605	COG2885	chlorophyll binding
KM547_RS00610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM547_RS00625	COG1803	Methylglyoxal synthase
KM547_RS00630	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KM547_RS00635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KM547_RS00640	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KM547_RS00645	COG0493	'glutamate synthase
KM547_RS00650	COG0069	glutamate synthase activity
KM547_RS00650	COG0070	glutamate synthase
KM547_RS00650	COG0067	glutamate synthase
KM547_RS00700	COG1111	helicase
KM547_RS00700	COG1205	dead DEAH box helicase
KM547_RS00740	COG2271	Major facilitator Superfamily
KM547_RS00795	COG1192	Involved in chromosome partitioning
KM547_RS00800	COG2062	phosphohistidine phosphatase, SixA
KM547_RS00810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM547_RS00815	COG2050	protein possibly involved in aromatic compounds catabolism
KM547_RS00825	COG2267	carboxylic ester hydrolase activity
KM547_RS00840	COG1881	PFAM PEBP family protein
KM547_RS00845	COG1968	undecaprenyl-diphosphatase activity
KM547_RS00850	COG0174	glutamine synthetase
KM547_RS00855	COG0347	Belongs to the P(II) protein family
KM547_RS00860	COG0004	ammonium transporteR
KM547_RS00865	COG3852	Histidine kinase
KM547_RS00870	COG2204	response regulator
KM547_RS00875	COG2032	superoxide dismutase activity
KM547_RS00880	COG2032	superoxide dismutase activity
KM547_RS00890	COG0183	Belongs to the thiolase family
KM547_RS00930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KM547_RS00935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KM547_RS00945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM547_RS00955	COG0612	Peptidase, M16
KM547_RS00965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM547_RS00970	COG3177	Filamentation induced by cAMP protein fic
KM547_RS00985	COG0596	Alpha beta hydrolase
KM547_RS00995	COG0727	PFAM Uncharacterised protein family (UPF0153)
KM547_RS01000	COG0318	PFAM AMP-dependent synthetase and ligase
KM547_RS01015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM547_RS01025	COG1181	Belongs to the D-alanine--D-alanine ligase family
KM547_RS01045	COG4232	protein-disulfide reductase activity
KM547_RS01050	COG0564	pseudouridine synthase activity
KM547_RS01075	COG0681	Belongs to the peptidase S26 family
KM547_RS01095	COG0583	DNA-binding transcription factor activity
KM547_RS01100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM547_RS01105	COG2224	Isocitrate lyase
KM547_RS01110	COG3706	GGDEF domain
KM547_RS01135	COG0659	secondary active sulfate transmembrane transporter activity
KM547_RS01165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM547_RS01170	COG2130	NADP-dependent
KM547_RS01185	COG1187	pseudouridine synthase activity
KM547_RS01195	COG1643	Atp-dependent helicase
KM547_RS01200	COG0084	hydrolase, TatD family'
KM547_RS01290	COG0842	Transport permease protein
KM547_RS01295	COG1131	(ABC) transporter
KM547_RS01300	COG0633	Ferredoxin
KM547_RS01300	COG0543	2 iron, 2 sulfur cluster binding
KM547_RS01310	COG1476	TRANSCRIPTIONal
KM547_RS01320	COG4555	ABC transporter
KM547_RS01340	COG0625	glutathione transferase activity
KM547_RS01450	COG1199	ATP-dependent helicase activity
KM547_RS01495	COG0628	permease
KM547_RS01515	COG2133	pyrroloquinoline quinone binding
KM547_RS01535	COG0456	acetyltransferase
KM547_RS01535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM547_RS01585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM547_RS01645	COG5463	Belongs to the UPF0441 family
KM547_RS01650	COG0754	glutathionylspermidine amidase activity
KM547_RS01660	COG0714	Associated with various cellular activities
KM547_RS01695	COG1522	sequence-specific DNA binding
KM547_RS01715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM547_RS01730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM547_RS01735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM547_RS01760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM547_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS01795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KM547_RS01805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM547_RS01810	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KM547_RS01870	COG0606	chelatase, subunit chli
KM547_RS01875	COG2960	long-chain fatty acid transporting porin activity
KM547_RS01900	COG1166	arginine decarboxylase activity
KM547_RS01905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM547_RS01910	COG1819	glycosyl
KM547_RS01915	COG2755	lipolytic protein G-D-S-L family
KM547_RS01915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KM547_RS01920	COG0583	DNA-binding transcription factor activity
KM547_RS01940	COG4221	oxidoreductase activity
KM547_RS01960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM547_RS01980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KM547_RS01990	COG2814	Major facilitator Superfamily
KM547_RS02000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KM547_RS02005	COG0739	heme binding
KM547_RS02010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM547_RS02060	COG1064	alcohol dehydrogenase
KM547_RS02065	COG2234	aminopeptidase activity
KM547_RS02075	COG4942	peptidase
KM547_RS02080	COG0793	Belongs to the peptidase S41A family
KM547_RS02115	COG0531	amino acid
KM547_RS02120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KM547_RS02120	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KM547_RS02125	COG1486	melibiose metabolic process
KM547_RS02140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM547_RS02145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM547_RS02150	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KM547_RS02180	COG0109	protoheme IX farnesyltransferase activity
KM547_RS02195	COG0358	DNA primase activity
KM547_RS02200	COG1295	ribonuclease BN
KM547_RS02220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM547_RS02225	COG2308	Evidence 4 Homologs of previously reported genes of
KM547_RS02240	COG2133	pyrroloquinoline quinone binding
KM547_RS02265	COG0531	amino acid
KM547_RS02275	COG4948	Mandelate Racemase Muconate Lactonizing
KM547_RS02285	COG4771	TonB-dependent receptor
KM547_RS02345	COG5383	Protein conserved in bacteria
KM547_RS02365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM547_RS02380	COG1652	LysM domain
KM547_RS02390	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KM547_RS02450	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM547_RS02455	COG3118	belongs to the thioredoxin family
KM547_RS02465	COG2884	Cell division ATP-binding protein ftsE
KM547_RS02470	COG2177	Part of the ABC transporter FtsEX involved in
KM547_RS02475	COG2201	protein-glutamate methylesterase activity
KM547_RS02480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KM547_RS02485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM547_RS02490	COG2860	membrane
KM547_RS02495	COG1252	NADH dehydrogenase
KM547_RS02500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM547_RS02510	COG0534	Mate efflux family protein
KM547_RS02515	COG0616	signal peptide processing
KM547_RS02525	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS02540	COG0009	L-threonylcarbamoyladenylate synthase
KM547_RS02545	COG1754	DNA topoisomerase type I activity
KM547_RS02545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM547_RS02550	COG1714	RDD family
KM547_RS02565	COG0758	DNA mediated transformation
KM547_RS02570	COG1652	LysM domain
KM547_RS02575	COG0242	peptide deformylase activity
KM547_RS02580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM547_RS02585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM547_RS02585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM547_RS02590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KM547_RS02605	COG1215	transferase activity, transferring glycosyl groups
KM547_RS02625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KM547_RS02640	COG1490	D-aminoacyl-tRNA deacylase activity
KM547_RS02645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM547_RS02660	COG1609	Transcriptional regulator
KM547_RS02670	COG0366	Alpha amylase catalytic
KM547_RS02675	COG0366	Alpha amylase catalytic
KM547_RS02755	COG4974	Belongs to the 'phage' integrase family
KM547_RS02785	COG1074	ATP-dependent DNA helicase activity
KM547_RS02800	COG0596	Alpha beta hydrolase
KM547_RS02815	COG1309	transcriptional regulator
KM547_RS02850	COG0840	transmembrane signaling receptor activity
KM547_RS02865	COG3546	catalase activity
KM547_RS02870	COG3685	Protein conserved in bacteria
KM547_RS02875	COG3685	Protein conserved in bacteria
KM547_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS02890	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KM547_RS02905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM547_RS02920	COG0028	Belongs to the TPP enzyme family
KM547_RS02925	COG4191	Histidine kinase
KM547_RS02950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM547_RS02950	COG1648	precorrin-2 dehydrogenase activity
KM547_RS02955	COG0784	Response regulator, receiver
KM547_RS02955	COG2198	Histidine kinase
KM547_RS02955	COG2205	protein histidine kinase activity
KM547_RS02960	COG1116	anion transmembrane transporter activity
KM547_RS02960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM547_RS02975	COG2223	nitrite transmembrane transporter activity
KM547_RS02980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM547_RS02985	COG2146	nitrite reductase [NAD(P)H] activity
KM547_RS02990	COG0243	molybdopterin cofactor binding
KM547_RS03015	COG1640	4-alpha-glucanotransferase
KM547_RS03020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KM547_RS03030	COG0297	glycogen (starch) synthase activity
KM547_RS03040	COG2204	response regulator
KM547_RS03065	COG0181	hydroxymethylbilane synthase activity
KM547_RS03080	COG1733	regulation of RNA biosynthetic process
KM547_RS03095	COG1505	serine-type exopeptidase activity
KM547_RS03100	COG0436	Aminotransferase
KM547_RS03110	COG2832	Protein of unknown function (DUF454)
KM547_RS03165	COG2226	methyltransferase
KM547_RS03195	COG0308	aminopeptidase N
KM547_RS03200	COG0596	Alpha beta hydrolase
KM547_RS03200	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM547_RS03225	COG2010	Cytochrome c
KM547_RS03235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KM547_RS03245	COG3284	Transcriptional regulator
KM547_RS03250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM547_RS03255	COG1077	Cell shape determining protein MreB Mrl
KM547_RS03260	COG1792	Involved in formation and maintenance of cell shape
KM547_RS03270	COG0768	penicillin binding
KM547_RS03275	COG0772	Belongs to the SEDS family
KM547_RS03290	COG2951	lytic endotransglycosylase activity
KM547_RS03300	COG1686	Belongs to the peptidase S11 family
KM547_RS03315	COG0321	lipoyl(octanoyl) transferase activity
KM547_RS03320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KM547_RS03350	COG1051	belongs to the nudix hydrolase family
KM547_RS03350	COG1056	cytidyltransferase-related domain
KM547_RS03370	COG1090	epimerase
KM547_RS03380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM547_RS03385	COG0673	inositol 2-dehydrogenase activity
KM547_RS03390	COG2823	Periplasmic or secreted lipoprotein
KM547_RS03400	COG2205	protein histidine kinase activity
KM547_RS03400	COG2202	Pas domain
KM547_RS03405	COG0784	Response regulator, receiver
KM547_RS03410	COG4191	Histidine kinase
KM547_RS03420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM547_RS03425	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS03440	COG4305	rare lipoprotein A
KM547_RS03455	COG3250	beta-galactosidase activity
KM547_RS03470	COG2188	Transcriptional regulator
KM547_RS03480	COG1609	Transcriptional regulator
KM547_RS03485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM547_RS03490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM547_RS03540	COG0494	nUDIX hydrolase
KM547_RS03550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM547_RS03575	COG2226	methyltransferase
KM547_RS03615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KM547_RS03635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM547_RS03655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM547_RS03660	COG0667	Aldo Keto reductase
KM547_RS03695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KM547_RS03700	COG4181	ATPase activity
KM547_RS03715	COG0642	Histidine kinase
KM547_RS03725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM547_RS03730	COG0861	Integral membrane protein TerC family
KM547_RS03735	COG1704	LemA family
KM547_RS03765	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM547_RS03770	COG2967	ApaG domain
KM547_RS03775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KM547_RS03780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KM547_RS03785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM547_RS03790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KM547_RS03800	COG2096	Adenosyltransferase
KM547_RS03810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM547_RS03815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM547_RS03830	COG0673	inositol 2-dehydrogenase activity
KM547_RS03855	COG0697	spore germination
KM547_RS03860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KM547_RS03885	COG2197	response regulator
KM547_RS03895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM547_RS03905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KM547_RS03915	COG0583	DNA-binding transcription factor activity
KM547_RS03920	COG3634	alkyl hydroperoxide reductase activity
KM547_RS03960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM547_RS03960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM547_RS04030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM547_RS04035	COG1404	Belongs to the peptidase S8 family
KM547_RS04045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM547_RS04065	COG1295	ribonuclease BN
KM547_RS04070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM547_RS04090	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM547_RS04115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KM547_RS04120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KM547_RS04145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KM547_RS04155	COG0193	aminoacyl-tRNA hydrolase activity
KM547_RS04160	COG0012	GTP binding
KM547_RS04180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KM547_RS04190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM547_RS04195	COG0250	Participates in transcription elongation, termination and antitermination
KM547_RS04200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM547_RS04215	COG0222	ribosome binding
KM547_RS04225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM547_RS04240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KM547_RS04245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KM547_RS04250	COG0051	transcription antitermination factor activity, RNA binding
KM547_RS04260	COG0088	Forms part of the polypeptide exit tunnel
KM547_RS04265	COG0089	rRNA binding
KM547_RS04270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KM547_RS04285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KM547_RS04295	COG0255	Belongs to the universal ribosomal protein uL29 family
KM547_RS04300	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KM547_RS04310	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KM547_RS04315	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KM547_RS04345	COG1841	ribosomal large subunit assembly
KM547_RS04355	COG0201	protein transport
KM547_RS04380	COG0203	ribosomal protein L17
KM547_RS04385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM547_RS04395	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KM547_RS04415	COG1217	gtp-binding protein TYPA
KM547_RS04420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM547_RS04430	COG0039	L-malate dehydrogenase activity
KM547_RS04450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM547_RS04455	COG0625	glutathione transferase activity
KM547_RS04500	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM547_RS04500	COG1902	pentaerythritol trinitrate reductase activity
KM547_RS04505	COG0604	alcohol dehydrogenase
KM547_RS04510	COG0667	Aldo Keto reductase
KM547_RS04520	COG2814	Major facilitator Superfamily
KM547_RS04525	COG0583	DNA-binding transcription factor activity
KM547_RS04530	COG2885	chlorophyll binding
KM547_RS04545	COG0156	8-amino-7-oxononanoate synthase activity
KM547_RS04550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KM547_RS04555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KM547_RS04560	COG4208	sulfate ABC transporter
KM547_RS04565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KM547_RS04585	COG0588	phosphoglycerate mutase activity
KM547_RS04590	COG0285	dihydrofolate synthase activity
KM547_RS04610	COG2833	Protein of unknown function (DUF455)
KM547_RS04620	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KM547_RS04625	COG0671	phosphoesterase, PA-phosphatase related
KM547_RS04630	COG0438	transferase activity, transferring glycosyl groups
KM547_RS04640	COG0248	Ppx GppA phosphatase
KM547_RS04645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM547_RS04660	COG4783	chaperone-mediated protein folding
KM547_RS04675	COG0473	3-isopropylmalate dehydrogenase activity
KM547_RS04710	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM547_RS04720	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KM547_RS04760	COG1388	LysM domain
KM547_RS04760	COG3942	CHAP domain
KM547_RS04765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM547_RS04775	COG0328	RNA-DNA hybrid ribonuclease activity
KM547_RS04780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM547_RS04785	COG0631	protein serine/threonine phosphatase activity
KM547_RS04805	COG0859	PFAM glycosyl transferase family 9
KM547_RS04815	COG1234	tRNA 3'-trailer cleavage
KM547_RS04820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM547_RS04830	COG0315	cyclic pyranopterin monophosphate synthase activity
KM547_RS04835	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KM547_RS04840	COG0314	molybdopterin synthase activity
KM547_RS04935	COG1002	Type II restriction enzyme, methylase subunits
KM547_RS04975	COG0537	adenosine 5'-monophosphoramidase activity
KM547_RS04995	COG0714	Associated with various cellular activities
KM547_RS05020	COG1399	metal-binding, possibly nucleic acid-binding protein
KM547_RS05025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM547_RS05030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM547_RS05035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM547_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS05045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM547_RS05055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM547_RS05060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM547_RS05065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KM547_RS05085	COG4115	mRNA cleavage
KM547_RS05090	COG2161	toxin-antitoxin pair type II binding
KM547_RS05125	COG0587	DNA-directed DNA polymerase activity
KM547_RS05140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KM547_RS05145	COG0372	Belongs to the citrate synthase family
KM547_RS05190	COG2373	Large extracellular alpha-helical protein
KM547_RS05220	COG4953	penicillin-binding protein 1C
KM547_RS05230	COG0678	peroxiredoxin activity
KM547_RS05255	COG0604	alcohol dehydrogenase
KM547_RS05260	COG0330	HflC and HflK could
KM547_RS05265	COG0330	HflC and HflK could
KM547_RS05280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KM547_RS05340	COG4804	nuclease activity
KM547_RS05345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KM547_RS05385	COG0492	ferredoxin-NADP+ reductase activity
KM547_RS05405	COG3459	Glycosyltransferase 36 associated
KM547_RS05415	COG1063	alcohol dehydrogenase
KM547_RS05440	COG0753	catalase activity
KM547_RS05445	COG5001	Diguanylate cyclase
KM547_RS05445	COG4251	negative regulation of phosphorylation
KM547_RS05445	COG3706	GGDEF domain
KM547_RS05445	COG2203	Gaf domain
KM547_RS05450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KM547_RS05450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KM547_RS05475	COG2814	Major facilitator Superfamily
KM547_RS05495	COG2194	sulfuric ester hydrolase activity
KM547_RS05505	COG0745	RESPONSE REGULATOR receiver
KM547_RS05510	COG2205	protein histidine kinase activity
KM547_RS05530	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KM547_RS05535	COG2894	cell division
KM547_RS05540	COG0850	regulation of cytokinetic process
KM547_RS05550	COG4585	Histidine kinase
KM547_RS05570	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM547_RS05575	COG1216	Glycosyl transferase, family 2
KM547_RS05580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM547_RS05590	COG1199	ATP-dependent helicase activity
KM547_RS05610	COG0189	ligase activity
KM547_RS05625	COG0835	chemotaxis
KM547_RS05630	COG0840	transmembrane signaling receptor activity
KM547_RS05635	COG0643	Histidine kinase
KM547_RS05635	COG2198	Histidine kinase
KM547_RS05635	COG0784	Response regulator, receiver
KM547_RS05640	COG2201	protein-glutamate methylesterase activity
KM547_RS05700	COG3142	Participates in the control of copper homeostasis
KM547_RS05705	COG1446	asparaginase
KM547_RS05770	COG3537	Alpha-1,2-mannosidase
KM547_RS05780	COG1472	Belongs to the glycosyl hydrolase 3 family
KM547_RS05795	COG1472	Belongs to the glycosyl hydrolase 3 family
KM547_RS05805	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KM547_RS05810	COG3858	chitin binding
KM547_RS05810	COG1388	LysM domain
KM547_RS05825	COG0837	glucose binding
KM547_RS05835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM547_RS05845	COG0494	nUDIX hydrolase
KM547_RS05850	COG1218	3'(2'),5'-bisphosphate nucleotidase
KM547_RS05855	COG3956	TIGRFAM MazG family protein
KM547_RS05860	COG1742	UPF0060 membrane protein
KM547_RS05865	COG0330	HflC and HflK could
KM547_RS05905	COG0697	spore germination
KM547_RS05935	COG2124	cytochrome p450
KM547_RS05940	COG2124	cytochrome p450
KM547_RS05945	COG1141	Ferredoxin
KM547_RS05950	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS05955	COG2124	cytochrome p450
KM547_RS05960	COG0142	geranyltranstransferase activity
KM547_RS05965	COG1657	PFAM Prenyltransferase squalene oxidase
KM547_RS05975	COG1304	FMN binding
KM547_RS05980	COG1960	acyl-CoA dehydrogenase activity
KM547_RS06025	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KM547_RS06030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM547_RS06035	COG0463	Glycosyl transferase, family 2
KM547_RS06040	COG0517	IMP dehydrogenase activity
KM547_RS06045	COG2982	Protein involved in outer membrane biogenesis
KM547_RS06050	COG1272	protein, Hemolysin III
KM547_RS06055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KM547_RS06060	COG0739	heme binding
KM547_RS06065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM547_RS06070	COG0626	cystathionine gamma-synthase activity
KM547_RS06075	COG0460	homoserine dehydrogenase
KM547_RS06075	COG0527	aspartate kinase activity
KM547_RS06080	COG0596	Alpha beta hydrolase
KM547_RS06080	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM547_RS06090	COG1760	l-serine dehydratase
KM547_RS06105	COG3038	cytochrome b561
KM547_RS06130	COG2814	Major facilitator Superfamily
KM547_RS06140	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM547_RS06150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM547_RS06155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM547_RS06175	COG0259	pyridoxamine-phosphate oxidase activity
KM547_RS06230	COG0519	Catalyzes the synthesis of GMP from XMP
KM547_RS06245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KM547_RS06265	COG0840	transmembrane signaling receptor activity
KM547_RS06275	COG1113	amino acid transport
KM547_RS06295	COG2239	Acts as a magnesium transporter
KM547_RS06300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KM547_RS06305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM547_RS06315	COG1660	Displays ATPase and GTPase activities
KM547_RS06325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM547_RS06340	COG1137	ATPase activity
KM547_RS06355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KM547_RS06420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM547_RS06445	COG0628	permease
KM547_RS06455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM547_RS06460	COG3178	'Phosphotransferase
KM547_RS06475	COG1555	photosystem II stabilization
KM547_RS06495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KM547_RS06500	COG1477	protein flavinylation
KM547_RS06525	COG4774	siderophore transport
KM547_RS06530	COG2146	nitrite reductase [NAD(P)H] activity
KM547_RS06540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM547_RS06545	COG0719	Fe-S assembly protein
KM547_RS06550	COG0396	ATPase activity
KM547_RS06555	COG0719	Fe-S assembly protein
KM547_RS06570	COG0693	protein deglycase activity
KM547_RS06585	COG0739	heme binding
KM547_RS06600	COG1764	response to oxidative stress
KM547_RS06610	COG0384	phenazine biosynthesis protein PhzF
KM547_RS06615	COG0527	aspartate kinase activity
KM547_RS06640	COG0142	geranyltranstransferase activity
KM547_RS06645	COG0629	single-stranded DNA binding
KM547_RS06650	COG3550	peptidyl-serine autophosphorylation
KM547_RS06670	COG3104	oligopeptide transport
KM547_RS06675	COG1297	OPT oligopeptide transporter protein
KM547_RS06680	COG0823	Involved in the tonB-independent uptake of proteins
KM547_RS06680	COG1506	peptidase
KM547_RS06700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM547_RS06710	COG2879	small protein
KM547_RS06715	COG1966	Carbon starvation protein
KM547_RS06740	COG1515	deoxyribonuclease V activity
KM547_RS06760	COG2211	Major facilitator Superfamily
KM547_RS06785	COG2203	Gaf domain
KM547_RS06785	COG3706	GGDEF domain
KM547_RS06785	COG4251	negative regulation of phosphorylation
KM547_RS06785	COG5001	Diguanylate cyclase
KM547_RS06790	COG0835	chemotaxis
KM547_RS06795	COG0840	transmembrane signaling receptor activity
KM547_RS06800	COG0840	transmembrane signaling receptor activity
KM547_RS06805	COG0840	transmembrane signaling receptor activity
KM547_RS06810	COG0643	Histidine kinase
KM547_RS06810	COG2198	Histidine kinase
KM547_RS06820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM547_RS06840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KM547_RS06860	COG4452	Inner membrane protein CreD
KM547_RS06885	COG0735	belongs to the Fur family
KM547_RS06965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM547_RS07065	COG1187	pseudouridine synthase activity
KM547_RS07090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM547_RS07115	COG1132	(ABC) transporter
KM547_RS07185	COG1981	membrane
KM547_RS07210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KM547_RS07215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KM547_RS07225	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KM547_RS07235	COG0750	zinc metalloprotease
KM547_RS07240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM547_RS07245	COG0575	Belongs to the CDS family
KM547_RS07250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM547_RS07260	COG0528	UMP kinase activity
KM547_RS07270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KM547_RS07310	COG0024	Methionine aminopeptidase
KM547_RS07325	COG1393	Belongs to the ArsC family
KM547_RS07330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM547_RS07340	COG0367	asparagine synthase
KM547_RS07380	COG1566	PFAM secretion protein HlyD family protein
KM547_RS07385	COG2814	Major facilitator Superfamily
KM547_RS07420	COG0557	exoribonuclease II activity
KM547_RS07430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM547_RS07440	COG3668	Plasmid stabilization system
KM547_RS07455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM547_RS07475	COG0704	Plays a role in the regulation of phosphate uptake
KM547_RS07485	COG0581	inorganic phosphate transmembrane transporter activity
KM547_RS07490	COG0573	inorganic phosphate transmembrane transporter activity
KM547_RS07495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM547_RS07500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM547_RS07520	COG0659	secondary active sulfate transmembrane transporter activity
KM547_RS07525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM547_RS07535	COG1024	Enoyl-CoA hydratase
KM547_RS07590	COG0784	Response regulator, receiver
KM547_RS07590	COG2205	protein histidine kinase activity
KM547_RS07590	COG5002	protein histidine kinase activity
KM547_RS07595	COG2733	membrane
KM547_RS07615	COG0686	Belongs to the AlaDH PNT family
KM547_RS07620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM547_RS07625	COG1396	sequence-specific DNA binding
KM547_RS07625	COG1917	Cupin 2, conserved barrel domain protein
KM547_RS07630	COG1012	belongs to the aldehyde dehydrogenase family
KM547_RS07645	COG2223	nitrite transmembrane transporter activity
KM547_RS07655	COG0243	molybdopterin cofactor binding
KM547_RS07670	COG0477	Major facilitator Superfamily
KM547_RS07675	COG3706	GGDEF domain
KM547_RS07680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM547_RS07685	COG0174	glutamine synthetase
KM547_RS07690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KM547_RS07695	COG0174	glutamine synthetase
KM547_RS07715	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM547_RS07735	COG3842	ATPase activity
KM547_RS07740	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM547_RS07745	COG1177	transmembrane transport
KM547_RS07750	COG1012	belongs to the aldehyde dehydrogenase family
KM547_RS07765	COG4535	Mg2 and Co2 transporter CorC
KM547_RS07780	COG1702	phosphate starvation-inducible protein PhoH
KM547_RS07795	COG0741	lytic transglycosylase activity
KM547_RS07800	COG0723	plastoquinol--plastocyanin reductase activity
KM547_RS07805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM547_RS07815	COG2857	Cytochrome c1
KM547_RS07820	COG0625	glutathione transferase activity
KM547_RS07825	COG2969	positive regulation of protein catabolic process
KM547_RS07865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KM547_RS07870	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS07875	COG2095	MarC family integral membrane protein
KM547_RS07885	COG1611	Belongs to the LOG family
KM547_RS07890	COG3275	phosphorelay sensor kinase activity
KM547_RS07935	COG0556	nucleotide-excision repair
KM547_RS07950	COG3505	Type IV secretory pathway VirD4
KM547_RS07970	COG2948	multi-organism process
KM547_RS08035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KM547_RS08045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KM547_RS08050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KM547_RS08100	COG0438	transferase activity, transferring glycosyl groups
KM547_RS08105	COG0438	transferase activity, transferring glycosyl groups
KM547_RS08115	COG0438	transferase activity, transferring glycosyl groups
KM547_RS08135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KM547_RS08145	COG1960	acyl-CoA dehydrogenase activity
KM547_RS08185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM547_RS08190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KM547_RS08190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KM547_RS08195	COG0802	atpase or kinase
KM547_RS08200	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM547_RS08205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KM547_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS08265	COG2081	HI0933 family
KM547_RS08270	COG4681	YaeQ
KM547_RS08275	COG0564	pseudouridine synthase activity
KM547_RS08285	COG0625	glutathione transferase activity
KM547_RS08290	COG0657	acetylesterase activity
KM547_RS08320	COG0513	Belongs to the DEAD box helicase family
KM547_RS08325	COG0488	(ABC) transporter
KM547_RS08340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM547_RS08350	COG1472	Belongs to the glycosyl hydrolase 3 family
KM547_RS08390	COG1846	Transcriptional regulator
KM547_RS08395	COG0339	signal peptide processing
KM547_RS08405	COG0386	Belongs to the glutathione peroxidase family
KM547_RS08430	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM547_RS08470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM547_RS08475	COG0084	hydrolase, TatD family'
KM547_RS08490	COG1960	acyl-CoA dehydrogenase activity
KM547_RS08500	COG0305	Participates in initiation and elongation during chromosome replication
KM547_RS08505	COG0415	Belongs to the DNA photolyase family
KM547_RS08520	COG0583	DNA-binding transcription factor activity
KM547_RS08535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM547_RS08610	COG1404	Belongs to the peptidase S8 family
KM547_RS08615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KM547_RS08620	COG2867	negative regulation of translational initiation
KM547_RS08630	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KM547_RS08635	COG0735	belongs to the Fur family
KM547_RS08640	COG0497	DNA recombination
KM547_RS08645	COG1420	regulation of RNA biosynthetic process
KM547_RS08650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KM547_RS08655	COG0443	Heat shock 70 kDa protein
KM547_RS08660	COG0484	heat shock protein binding
KM547_RS08665	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KM547_RS08670	COG0287	Prephenate dehydrogenase
KM547_RS08670	COG1605	Chorismate mutase
KM547_RS08680	COG1132	(ABC) transporter
KM547_RS08735	COG2850	peptidyl-arginine hydroxylation
KM547_RS08775	COG1131	(ABC) transporter
KM547_RS08780	COG1725	Transcriptional regulator
KM547_RS08790	COG0386	Belongs to the glutathione peroxidase family
KM547_RS08805	COG2900	Belongs to the SlyX family
KM547_RS08825	COG0646	methionine synthase
KM547_RS08825	COG1410	methionine synthase
KM547_RS08830	COG0646	methionine synthase
KM547_RS08830	COG1410	methionine synthase
KM547_RS08835	COG2226	methyltransferase
KM547_RS08840	COG1960	acyl-CoA dehydrogenase activity
KM547_RS08845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM547_RS08850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM547_RS08860	COG2902	Dehydrogenase
KM547_RS08890	COG2925	Exonuclease
KM547_RS08900	COG3844	kynureninase activity
KM547_RS08910	COG0662	Cupin 2, conserved barrel domain protein
KM547_RS08915	COG0288	reversible hydration of carbon dioxide
KM547_RS08960	COG2197	response regulator
KM547_RS08985	COG0316	Belongs to the HesB IscA family
KM547_RS08990	COG2977	Belongs to the P-Pant transferase superfamily
KM547_RS09025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KM547_RS09030	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KM547_RS09040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM547_RS09075	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KM547_RS09090	COG1228	amidohydrolase
KM547_RS09105	COG4221	oxidoreductase activity
KM547_RS09145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM547_RS09150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KM547_RS09155	COG1605	Chorismate mutase
KM547_RS09155	COG0077	Prephenate dehydratase
KM547_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS09240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM547_RS09260	COG2201	protein-glutamate methylesterase activity
KM547_RS09265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM547_RS09270	COG2197	response regulator
KM547_RS09290	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KM547_RS09295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM547_RS09300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM547_RS09305	COG1256	bacterial-type flagellum assembly
KM547_RS09305	COG4786	Flagellar basal body rod
KM547_RS09315	COG1706	bacterial-type flagellum-dependent cell motility
KM547_RS09320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KM547_RS09335	COG1749	Flagellar hook protein flgE
KM547_RS09345	COG1558	bacterial-type flagellum-dependent cell motility
KM547_RS09355	COG0784	Response regulator, receiver
KM547_RS09355	COG0835	chemotaxis
KM547_RS09400	COG1116	anion transmembrane transporter activity
KM547_RS09415	COG2915	High frequency lysogenization protein hflD homolog
KM547_RS09420	COG0482	sulfurtransferase activity
KM547_RS09440	COG0542	response to heat
KM547_RS09450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KM547_RS09460	COG0492	ferredoxin-NADP+ reductase activity
KM547_RS09465	COG1674	ftsk spoiiie
KM547_RS09495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM547_RS09500	COG0038	chloride channel
KM547_RS09535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM547_RS09570	COG1595	DNA-templated transcription, initiation
KM547_RS09590	COG3038	cytochrome b561
KM547_RS09620	COG2244	polysaccharide biosynthetic process
KM547_RS09660	COG0438	transferase activity, transferring glycosyl groups
KM547_RS09665	COG0438	transferase activity, transferring glycosyl groups
KM547_RS09685	COG1132	(ABC) transporter
KM547_RS09695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM547_RS09745	COG4644	lycopene metabolic process
KM547_RS09750	COG1649	PFAM Uncharacterised BCR, COG1649
KM547_RS09760	COG4644	lycopene metabolic process
KM547_RS09815	COG5000	phosphorelay sensor kinase activity
KM547_RS09815	COG5002	protein histidine kinase activity
KM547_RS09875	COG0784	Response regulator, receiver
KM547_RS09875	COG2205	protein histidine kinase activity
KM547_RS09880	COG2183	response to ionizing radiation
KM547_RS09885	COG0784	Response regulator, receiver
KM547_RS09885	COG4191	Histidine kinase
KM547_RS09895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM547_RS09895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KM547_RS09915	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM547_RS09925	COG1183	phosphatidylcholine synthase activity
KM547_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS09945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KM547_RS09955	COG0668	transmembrane transport
KM547_RS09960	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KM547_RS09975	COG1914	H( )-stimulated, divalent metal cation uptake system
KM547_RS09985	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KM547_RS09990	COG1501	Belongs to the glycosyl hydrolase 31 family
KM547_RS10020	COG0475	glutathione-regulated potassium exporter activity
KM547_RS10020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM547_RS10025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM547_RS10035	COG0746	molybdenum cofactor guanylyltransferase activity
KM547_RS10045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KM547_RS10055	COG1426	Protein conserved in bacteria
KM547_RS10065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KM547_RS10080	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM547_RS10080	COG1024	Enoyl-CoA hydratase
KM547_RS10085	COG0183	Belongs to the thiolase family
KM547_RS10090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM547_RS10100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM547_RS10105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KM547_RS10115	COG0776	regulation of translation
KM547_RS10120	COG0539	negative regulation of cytoplasmic translation
KM547_RS10125	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KM547_RS10130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM547_RS10140	COG2957	Belongs to the agmatine deiminase family
KM547_RS10145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM547_RS10185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM547_RS10185	COG0316	Belongs to the HesB IscA family
KM547_RS10200	COG0428	transporter
KM547_RS10215	COG1530	ribonuclease E activity
KM547_RS10245	COG1677	Flagellar hook-basal body complex protein FliE
KM547_RS10295	COG3190	flagellar
KM547_RS10305	COG1987	bacterial-type flagellum assembly
KM547_RS10310	COG1684	flagellar biosynthetic protein fliR
KM547_RS10360	COG0643	Histidine kinase
KM547_RS10360	COG0784	Response regulator, receiver
KM547_RS10360	COG2198	Histidine kinase
KM547_RS10365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM547_RS10375	COG1192	Involved in chromosome partitioning
KM547_RS10390	COG0745	RESPONSE REGULATOR receiver
KM547_RS10400	COG0840	transmembrane signaling receptor activity
KM547_RS10405	COG0840	transmembrane signaling receptor activity
KM547_RS10410	COG0840	transmembrane signaling receptor activity
KM547_RS10415	COG0840	transmembrane signaling receptor activity
KM547_RS10425	COG0840	transmembrane signaling receptor activity
KM547_RS10435	COG0840	transmembrane signaling receptor activity
KM547_RS10440	COG0840	transmembrane signaling receptor activity
KM547_RS10450	COG0840	transmembrane signaling receptor activity
KM547_RS10460	COG0835	chemotaxis
KM547_RS10470	COG0840	transmembrane signaling receptor activity
KM547_RS10480	COG0840	transmembrane signaling receptor activity
KM547_RS10560	COG0318	PFAM AMP-dependent synthetase and ligase
KM547_RS10565	COG1024	Enoyl-CoA hydratase
KM547_RS10570	COG0784	Response regulator, receiver
KM547_RS10570	COG2198	Histidine kinase
KM547_RS10570	COG2205	protein histidine kinase activity
KM547_RS10580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KM547_RS10595	COG4676	Protein conserved in bacteria
KM547_RS10615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KM547_RS10620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KM547_RS10630	COG0505	Belongs to the CarA family
KM547_RS10640	COG2258	MOSC domain
KM547_RS10645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM547_RS10655	COG1918	ferrous iron import across plasma membrane
KM547_RS10655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM547_RS10665	COG1024	Enoyl-CoA hydratase
KM547_RS10685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KM547_RS10705	COG0277	FAD linked oxidase domain protein
KM547_RS10710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM547_RS10725	COG0531	amino acid
KM547_RS10730	COG0531	amino acid
KM547_RS10735	COG0235	Class ii aldolase
KM547_RS10740	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM547_RS10745	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KM547_RS10760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KM547_RS10760	COG0140	phosphoribosyl-ATP diphosphatase activity
KM547_RS10775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KM547_RS10790	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM547_RS10795	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KM547_RS10805	COG0124	histidyl-tRNA synthetase
KM547_RS10810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM547_RS10820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KM547_RS10830	COG2951	lytic endotransglycosylase activity
KM547_RS10840	COG0527	aspartate kinase activity
KM547_RS10840	COG0460	homoserine dehydrogenase
KM547_RS10855	COG1012	belongs to the aldehyde dehydrogenase family
KM547_RS10870	COG0167	dihydroorotate dehydrogenase activity
KM547_RS10875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM547_RS10885	COG0210	DNA helicase
KM547_RS10890	COG0671	phosphoesterase, PA-phosphatase related
KM547_RS10905	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KM547_RS10925	COG0166	Belongs to the GPI family
KM547_RS10940	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KM547_RS10950	COG0617	tRNA 3'-terminal CCA addition
KM547_RS10970	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM547_RS10975	COG0477	Major facilitator Superfamily
KM547_RS10980	COG2115	Belongs to the xylose isomerase family
KM547_RS10985	COG1070	Carbohydrate kinase
KM547_RS10995	COG1501	Belongs to the glycosyl hydrolase 31 family
KM547_RS11020	COG0800	Aldolase
KM547_RS11035	COG3734	2-keto-3-deoxy-galactonokinase
KM547_RS11040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KM547_RS11050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM547_RS11060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM547_RS11065	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM547_RS11080	COG0352	thiamine-phosphate diphosphorylase activity
KM547_RS11080	COG0351	phosphomethylpyrimidine kinase
KM547_RS11105	COG0583	DNA-binding transcription factor activity
KM547_RS11110	COG1741	Belongs to the pirin family
KM547_RS11145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KM547_RS11150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KM547_RS11155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KM547_RS11160	COG1546	Belongs to the CinA family
KM547_RS11165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM547_RS11175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KM547_RS11180	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM547_RS11185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM547_RS11190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KM547_RS11195	COG1534	Rna-binding protein
KM547_RS11210	COG1238	metal cluster binding
KM547_RS11220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KM547_RS11235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KM547_RS11240	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KM547_RS11245	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KM547_RS11285	COG1253	flavin adenine dinucleotide binding
KM547_RS11300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM547_RS11340	COG0069	glutamate synthase activity
KM547_RS11345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM547_RS11360	COG1609	Transcriptional regulator
KM547_RS11365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KM547_RS11365	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM547_RS11370	COG1105	Belongs to the carbohydrate kinase PfkB family
KM547_RS11375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM547_RS11375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM547_RS11405	COG1136	(ABC) transporter
KM547_RS11405	COG0577	efflux transmembrane transporter activity
KM547_RS11460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM547_RS11470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM547_RS11475	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KM547_RS11485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM547_RS11495	COG0348	domain, Protein
KM547_RS11525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM547_RS11540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM547_RS11550	COG1663	tetraacyldisaccharide 4'-kinase activity
KM547_RS11555	COG1132	(ABC) transporter
KM547_RS11560	COG0848	biopolymer transport protein
KM547_RS11565	COG0811	peptide transport
KM547_RS11585	COG4591	ABC-type transport system involved in lipoprotein release permease component
KM547_RS11595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KM547_RS11610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KM547_RS11615	COG2009	succinate dehydrogenase
KM547_RS11625	COG0354	folic acid binding
KM547_RS11630	COG3842	ATPase activity
KM547_RS11635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM547_RS11650	COG0129	dihydroxy-acid dehydratase activity
KM547_RS11665	COG0395	ABC-type sugar transport system, permease component
KM547_RS11700	COG2350	Protein conserved in bacteria
KM547_RS11705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KM547_RS11715	COG1187	pseudouridine synthase activity
KM547_RS11745	COG0436	Aminotransferase
KM547_RS11750	COG4133	protoheme IX ABC transporter activity
KM547_RS11795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM547_RS11800	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM547_RS11805	COG4988	ABC transporter
KM547_RS11815	COG1294	oxidase, subunit
KM547_RS11840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KM547_RS11860	COG0165	Argininosuccinate lyase
KM547_RS11865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KM547_RS11875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KM547_RS11880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM547_RS11885	COG0137	argininosuccinate synthase activity
KM547_RS11890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KM547_RS11905	COG2166	iron-sulfur cluster assembly
KM547_RS11910	COG2814	Major facilitator Superfamily
KM547_RS11950	COG2010	Cytochrome c
KM547_RS11950	COG4993	Dehydrogenase
KM547_RS11980	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KM547_RS11990	COG4677	pectinesterase activity
KM547_RS11995	COG5434	Belongs to the glycosyl hydrolase 28 family
KM547_RS12020	COG0402	S-adenosylhomocysteine deaminase activity
KM547_RS12025	COG3548	integral membrane protein
KM547_RS12035	COG1509	lysine 2,3-aminomutase activity
KM547_RS12070	COG1862	Preprotein translocase
KM547_RS12080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KM547_RS12090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM547_RS12095	COG2755	lipolytic protein G-D-S-L family
KM547_RS12095	COG0657	acetylesterase activity
KM547_RS12100	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KM547_RS12105	COG3291	Pkd domain containing protein
KM547_RS12110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM547_RS12140	COG0644	oxidoreductase
KM547_RS12160	COG0405	Gamma-glutamyltransferase
KM547_RS12165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KM547_RS12180	COG0742	ribosomal rna small subunit methyltransferase
KM547_RS12210	COG4771	TonB-dependent receptor
KM547_RS12265	COG0531	amino acid
KM547_RS12280	COG0006	proline dipeptidase activity
KM547_RS12290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM547_RS12305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM547_RS12310	COG3938	Belongs to the proline racemase family
KM547_RS12320	COG0552	protein localization to endoplasmic reticulum
KM547_RS12325	COG1194	a g-specific adenine glycosylase
KM547_RS12370	COG0835	chemotaxis
KM547_RS12375	COG0840	transmembrane signaling receptor activity
KM547_RS12380	COG0840	transmembrane signaling receptor activity
KM547_RS12385	COG1201	RNA secondary structure unwinding
KM547_RS12395	COG3300	MHYT domain
KM547_RS12395	COG5001	Diguanylate cyclase
KM547_RS12405	COG1185	polyribonucleotide nucleotidyltransferase activity
KM547_RS12415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM547_RS12430	COG0195	Participates in both transcription termination and antitermination
KM547_RS12445	COG1007	ATP synthesis coupled electron transport
KM547_RS12480	COG1034	ATP synthesis coupled electron transport
KM547_RS12485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KM547_RS12490	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KM547_RS12495	COG0649	NAD binding
KM547_RS12500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM547_RS12510	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM547_RS12540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KM547_RS12600	COG2890	protein-(glutamine-N5) methyltransferase activity
KM547_RS12610	COG0688	phosphatidylethanolamine metabolic process
KM547_RS12625	COG0741	lytic transglycosylase activity
KM547_RS12630	COG0433	COG0433 Predicted ATPase
KM547_RS12635	COG0494	nUDIX hydrolase
KM547_RS12660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KM547_RS12680	COG1714	RDD family
KM547_RS12685	COG0717	Belongs to the dCTP deaminase family
KM547_RS12690	COG0489	protein tyrosine kinase activity
KM547_RS12705	COG4771	TonB-dependent receptor
KM547_RS12715	COG4771	TonB-dependent receptor
KM547_RS12720	COG0457	Tetratricopeptide repeat
KM547_RS12730	COG3590	peptidase
KM547_RS12740	COG0705	Rhomboid family
KM547_RS12765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM547_RS12770	COG2311	Membrane
KM547_RS12775	COG1047	Peptidyl-prolyl cis-trans
KM547_RS12780	COG0791	NLP P60 protein
KM547_RS12785	COG0791	NLP P60 protein
KM547_RS12790	COG1607	acyl-coa hydrolase
KM547_RS12800	COG1301	dicarboxylic acid transport
KM547_RS12805	COG1785	Belongs to the alkaline phosphatase family
KM547_RS12820	COG1722	exodeoxyribonuclease VII activity
KM547_RS12825	COG0142	geranyltranstransferase activity
KM547_RS12835	COG4104	PAAR repeat-containing protein
KM547_RS12850	COG0312	modulator of DNA gyrase
KM547_RS12860	COG0312	modulator of DNA gyrase
KM547_RS12880	COG2968	Membrane
KM547_RS12895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KM547_RS12910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KM547_RS12925	COG0495	leucyl-tRNA aminoacylation
KM547_RS12935	COG3118	belongs to the thioredoxin family
KM547_RS12950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KM547_RS12960	COG2040	homocysteine
KM547_RS12970	COG0346	lactoylglutathione lyase activity
KM547_RS12995	COG2878	Part of a membrane complex involved in electron transport
KM547_RS13010	COG1595	DNA-templated transcription, initiation
KM547_RS13035	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM547_RS13060	COG0251	oxidation-reduction process
KM547_RS13070	COG0392	lysyltransferase activity
KM547_RS13070	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM547_RS13100	COG2814	Major facilitator Superfamily
KM547_RS13105	COG1902	pentaerythritol trinitrate reductase activity
KM547_RS13110	COG0583	DNA-binding transcription factor activity
KM547_RS13125	COG2824	Alkylphosphonate utilization operon protein PhnA
KM547_RS13130	COG1047	Peptidyl-prolyl cis-trans
KM547_RS13135	COG1077	Cell shape determining protein MreB Mrl
KM547_RS13155	COG3287	FIST C domain
KM547_RS13155	COG2200	EAL domain
KM547_RS13155	COG2199	diguanylate cyclase activity
KM547_RS13170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM547_RS13180	COG1451	nucleotide metabolic process
KM547_RS13205	COG2198	Histidine kinase
KM547_RS13205	COG2205	protein histidine kinase activity
KM547_RS13205	COG0784	Response regulator, receiver
KM547_RS13215	COG2186	Transcriptional regulator
KM547_RS13220	COG3250	beta-galactosidase activity
KM547_RS13265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KM547_RS13265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KM547_RS13265	COG1703	isobutyryl-CoA mutase activity
KM547_RS13290	COG0183	Belongs to the thiolase family
KM547_RS13300	COG0443	Heat shock 70 kDa protein
KM547_RS13330	COG1793	dna ligase
KM547_RS13330	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KM547_RS13335	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KM547_RS13335	COG1793	dna ligase
KM547_RS13340	COG1201	RNA secondary structure unwinding
KM547_RS13355	COG1278	Cold shock
KM547_RS13360	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KM547_RS13365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM547_RS13370	COG1472	Belongs to the glycosyl hydrolase 3 family
KM547_RS13380	COG2954	triphosphatase activity
KM547_RS13390	COG2204	response regulator
KM547_RS13395	COG1381	Involved in DNA repair and RecF pathway recombination
KM547_RS13400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM547_RS13415	COG0681	Belongs to the peptidase S26 family
KM547_RS13420	COG0481	GTPase activity
KM547_RS13425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM547_RS13440	COG1024	Enoyl-CoA hydratase
KM547_RS13440	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM547_RS13455	COG2855	membrane
KM547_RS13470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KM547_RS13500	COG0534	Mate efflux family protein
KM547_RS13505	COG0335	large ribosomal subunit rRNA binding
KM547_RS13515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KM547_RS13520	COG0228	four-way junction DNA binding
KM547_RS13530	COG2070	2-Nitropropane dioxygenase
KM547_RS13535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM547_RS13555	COG0475	glutathione-regulated potassium exporter activity
KM547_RS13565	COG0625	glutathione transferase activity
KM547_RS13570	COG1082	Xylose isomerase domain protein TIM barrel
KM547_RS13580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM547_RS13585	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM547_RS13590	COG1129	ABC transporter
KM547_RS13595	COG1879	ABC-type sugar transport system periplasmic component
KM547_RS13600	COG1012	belongs to the aldehyde dehydrogenase family
KM547_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS13620	COG0129	dihydroxy-acid dehydratase activity
KM547_RS13645	COG2207	Transcriptional regulator
KM547_RS13690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM547_RS13715	COG4794	Type iii secretion
KM547_RS13745	COG0745	RESPONSE REGULATOR receiver
KM547_RS13795	COG3152	Membrane
KM547_RS13805	COG0156	8-amino-7-oxononanoate synthase activity
KM547_RS13815	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KM547_RS13820	COG1845	cytochrome c oxidase, subunit III
KM547_RS13825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM547_RS13835	COG0750	zinc metalloprotease
KM547_RS13860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KM547_RS13875	COG0196	riboflavin kinase activity
KM547_RS13900	COG2801	Transposase and inactivated derivatives
KM547_RS13915	COG0728	peptidoglycan biosynthetic process
KM547_RS13935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KM547_RS13940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KM547_RS13945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM547_RS13950	COG0824	Thioesterase
KM547_RS13965	COG1024	Enoyl-CoA hydratase
KM547_RS13970	COG1946	Acyl-CoA thioesterase
KM547_RS14025	COG1073	alpha beta
KM547_RS14050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM547_RS14100	COG1643	Atp-dependent helicase
KM547_RS14105	COG0783	Belongs to the Dps family
KM547_RS14110	COG0514	ATP-dependent DNA helicase (RecQ)
KM547_RS14135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KM547_RS14140	COG0602	queuosine metabolic process
KM547_RS14150	COG2885	chlorophyll binding
KM547_RS14165	COG0848	biopolymer transport protein
KM547_RS14175	COG0824	Thioesterase
KM547_RS14185	COG3158	transport of potassium into the cell
KM547_RS14190	COG0632	four-way junction helicase activity
KM547_RS14200	COG0217	transcriptional regulatory protein
KM547_RS14285	COG0488	(ABC) transporter
KM547_RS14340	COG4651	solute:proton antiporter activity
KM547_RS14340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM547_RS14350	COG4772	TonB-dependent receptor
KM547_RS14360	COG4264	IucA IucC family
KM547_RS14365	COG2814	Major facilitator Superfamily
KM547_RS14370	COG4264	IucA IucC family
KM547_RS14375	COG0019	diaminopimelate decarboxylase activity
KM547_RS14400	COG0542	response to heat
KM547_RS14425	COG0454	-acetyltransferase
KM547_RS14445	COG1877	trehalose-phosphatase activity
KM547_RS14450	COG3387	PFAM Glycoside hydrolase 15-related
KM547_RS14460	COG4993	Dehydrogenase
KM547_RS14465	COG0840	transmembrane signaling receptor activity
KM547_RS14475	COG0564	pseudouridine synthase activity
KM547_RS14480	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KM547_RS14490	COG1125	glycine betaine transport
KM547_RS14495	COG1174	glycine betaine transport
KM547_RS14510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KM547_RS14520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KM547_RS14520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM547_RS14550	COG3657	addiction module killer protein
KM547_RS14555	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM547_RS14590	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM547_RS14605	COG0745	RESPONSE REGULATOR receiver
KM547_RS14615	COG0189	ligase activity
KM547_RS14625	COG3511	phospholipase C
KM547_RS14645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM547_RS14660	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KM547_RS14670	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KM547_RS14675	COG0174	glutamine synthetase
KM547_RS14710	COG2022	thiamine diphosphate biosynthetic process
KM547_RS14720	COG0471	metal ion transport
KM547_RS14720	COG3273	potassium ion transport
KM547_RS14735	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM547_RS14750	COG1609	Transcriptional regulator
KM547_RS14760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM547_RS14785	COG1115	amino acid carrier protein
KM547_RS14805	COG0438	transferase activity, transferring glycosyl groups
KM547_RS14810	COG0840	transmembrane signaling receptor activity
KM547_RS14815	COG0529	Catalyzes the synthesis of activated sulfate
KM547_RS14815	COG2895	sulfate adenylyltransferase (ATP) activity
KM547_RS14825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KM547_RS14830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM547_RS14835	COG0175	sulfate reduction
KM547_RS14865	COG1393	Belongs to the ArsC family
KM547_RS14875	COG2198	Histidine kinase
KM547_RS14875	COG2205	protein histidine kinase activity
KM547_RS14875	COG0784	Response regulator, receiver
KM547_RS14895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM547_RS14895	COG1648	precorrin-2 dehydrogenase activity
KM547_RS14920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KM547_RS14930	COG2351	hydroxyisourate hydrolase activity
KM547_RS14935	COG2072	flavoprotein involved in K transport
KM547_RS14955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM547_RS15000	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KM547_RS15005	COG3588	fructose-bisphosphate aldolase
KM547_RS15010	COG0469	pyruvate kinase activity
KM547_RS15055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM547_RS15060	COG3047	cAMP biosynthetic process
KM547_RS15085	COG0640	Transcriptional regulator
KM547_RS15095	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM547_RS15100	COG4149	molybdate abc transporter
KM547_RS15105	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KM547_RS15145	COG1376	ErfK ybiS ycfS ynhG family protein
KM547_RS15150	COG0739	heme binding
KM547_RS15175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KM547_RS15210	COG0714	Associated with various cellular activities
KM547_RS15240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM547_RS15255	COG0372	Belongs to the citrate synthase family
KM547_RS15260	COG0254	rRNA binding
KM547_RS15270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM547_RS15295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM547_RS15300	COG1758	RNA polymerase activity
KM547_RS15305	COG0194	GDP metabolic process
KM547_RS15310	COG1561	YicC-like family, N-terminal region
KM547_RS15315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KM547_RS15320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KM547_RS15325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM547_RS15345	COG0006	proline dipeptidase activity
KM547_RS15350	COG3079	Belongs to the UPF0149 family
KM547_RS15375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM547_RS15385	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM547_RS15400	COG1773	rubredoxin
KM547_RS15415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KM547_RS15435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM547_RS15445	COG1940	carbohydrate kinase activity
KM547_RS15460	COG0671	phosphoesterase, PA-phosphatase related
KM547_RS15470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KM547_RS15480	COG0563	adenylate kinase activity
KM547_RS15500	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KM547_RS15510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KM547_RS15540	COG0840	transmembrane signaling receptor activity
KM547_RS15565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM547_RS15585	COG0066	3-isopropylmalate dehydratase activity
KM547_RS15590	COG0473	3-isopropylmalate dehydrogenase activity
KM547_RS15595	COG3706	GGDEF domain
KM547_RS15605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KM547_RS15610	COG1538	Outer membrane efflux protein
KM547_RS15615	COG1519	Transferase
KM547_RS15620	COG1560	Kdo2-lipid A biosynthetic process
KM547_RS15705	COG0280	phosphate acetyltransferase
KM547_RS15705	COG0281	malic enzyme
KM547_RS15710	COG1301	dicarboxylic acid transport
KM547_RS15720	COG4191	Histidine kinase
KM547_RS15755	COG0642	Histidine kinase
KM547_RS15770	COG2851	Citrate transporter
KM547_RS15775	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS15830	COG1162	GTPase activity
KM547_RS15880	COG0436	Aminotransferase
KM547_RS15905	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KM547_RS15920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KM547_RS15925	COG1228	amidohydrolase
KM547_RS15940	COG1307	EDD domain protein, DegV family
KM547_RS15950	COG0697	spore germination
KM547_RS15960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM547_RS15970	COG3791	Glutathione-dependent formaldehyde-activating
KM547_RS15975	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KM547_RS15990	COG2205	protein histidine kinase activity
KM547_RS16030	COG2207	Transcriptional regulator
KM547_RS16055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM547_RS16085	COG0617	tRNA 3'-terminal CCA addition
KM547_RS16140	COG0739	heme binding
KM547_RS16150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KM547_RS16155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM547_RS16165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM547_RS16170	COG1181	Belongs to the D-alanine--D-alanine ligase family
KM547_RS16195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM547_RS16210	COG3116	cell division
KM547_RS16215	COG0275	rRNA processing
KM547_RS16220	COG2001	Belongs to the MraZ family
KM547_RS16250	COG0792	nuclease activity
KM547_RS16255	COG1988	membrane-bound metal-dependent
KM547_RS16260	COG0277	FAD linked oxidase domain protein
KM547_RS16265	COG0745	RESPONSE REGULATOR receiver
KM547_RS16270	COG2205	protein histidine kinase activity
KM547_RS16280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KM547_RS16285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KM547_RS16310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KM547_RS16315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM547_RS16320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KM547_RS16335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM547_RS16335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM547_RS16345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KM547_RS16375	COG0477	Major facilitator Superfamily
KM547_RS16380	COG0488	(ABC) transporter
KM547_RS16385	COG0242	peptide deformylase activity
KM547_RS16400	COG1960	acyl-CoA dehydrogenase activity
KM547_RS16415	COG1696	Membrane protein involved in D-alanine export
KM547_RS16420	COG1696	Membrane protein involved in D-alanine export
KM547_RS16440	COG1215	transferase activity, transferring glycosyl groups
KM547_RS16450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM547_RS16500	COG2188	Transcriptional regulator
KM547_RS16510	COG1450	Type ii and iii secretion system protein
KM547_RS16525	COG3166	PFAM Fimbrial assembly family protein
KM547_RS16530	COG3156	type II secretion system protein K
KM547_RS16535	COG4795	General secretion pathway protein
KM547_RS16540	COG2165	general secretion pathway protein
KM547_RS16545	COG4970	Tfp pilus assembly protein FimT
KM547_RS16550	COG2165	general secretion pathway protein
KM547_RS16555	COG1459	type II secretion system
KM547_RS16560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM547_RS16565	COG1404	Belongs to the peptidase S8 family
KM547_RS16570	COG5295	Hep Hag repeat protein
KM547_RS16575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM547_RS16575	COG0047	phosphoribosylformylglycinamidine synthase activity
KM547_RS16580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM547_RS16585	COG4974	Belongs to the 'phage' integrase family
KM547_RS16605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KM547_RS16615	COG0525	valine-tRNA ligase activity
KM547_RS16635	COG1183	phosphatidylcholine synthase activity
KM547_RS16645	COG0442	prolyl-tRNA aminoacylation
KM547_RS16660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KM547_RS16665	COG1127	ABC transporter
KM547_RS16670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KM547_RS16670	COG3218	ABC-type transport auxiliary lipoprotein component
KM547_RS16700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM547_RS16705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM547_RS16710	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KM547_RS16710	COG0662	Cupin 2, conserved barrel domain protein
KM547_RS16735	COG2086	electron transfer activity
KM547_RS16750	COG0546	phosphoglycolate phosphatase activity
KM547_RS16750	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KM547_RS16755	COG0277	FAD linked oxidase domain protein
KM547_RS16760	COG0300	oxidoreductase activity
KM547_RS16765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM547_RS16780	COG0493	'glutamate synthase
KM547_RS16805	COG1216	Glycosyl transferase, family 2
KM547_RS16805	COG0438	transferase activity, transferring glycosyl groups
KM547_RS16810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM547_RS16820	COG1216	Glycosyl transferase, family 2
KM547_RS16820	COG0438	transferase activity, transferring glycosyl groups
KM547_RS16825	COG1216	Glycosyl transferase, family 2
KM547_RS16825	COG0438	transferase activity, transferring glycosyl groups
KM547_RS16830	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KM547_RS16845	COG0626	cystathionine gamma-synthase activity
KM547_RS16875	COG0625	glutathione transferase activity
KM547_RS16890	COG0720	synthase
KM547_RS16900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KM547_RS16905	COG1956	GAF domain-containing protein
KM547_RS16915	COG4206	TonB-dependent receptor
KM547_RS16920	COG0546	phosphoglycolate phosphatase activity
KM547_RS16945	COG0339	signal peptide processing
KM547_RS16950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM547_RS16960	COG2217	Heavy metal translocating P-type atpase
KM547_RS16975	COG2132	Multicopper oxidase
KM547_RS16995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM547_RS17005	COG1136	(ABC) transporter
KM547_RS17025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KM547_RS17040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KM547_RS17055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KM547_RS17065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KM547_RS17075	COG0356	it plays a direct role in the translocation of protons across the membrane
KM547_RS17090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM547_RS17095	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM547_RS17130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM547_RS17135	COG0697	spore germination
KM547_RS17140	COG1666	GTP binding
KM547_RS17150	COG1187	pseudouridine synthase activity
KM547_RS17155	COG2813	Specifically methylates the guanine in position
KM547_RS17175	COG2205	protein histidine kinase activity
KM547_RS17175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM547_RS17200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM547_RS17280	COG0842	Transport permease protein
KM547_RS17285	COG1131	(ABC) transporter
KM547_RS17290	COG0025	NhaP-type Na H and K H
KM547_RS17300	COG1573	uracil-dna glycosylase
KM547_RS17310	COG3384	dioxygenase
KM547_RS17335	COG0667	Aldo Keto reductase
KM547_RS17345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM547_RS17350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM547_RS17370	COG3706	GGDEF domain
KM547_RS17385	COG5001	Diguanylate cyclase
KM547_RS17415	COG4106	trans-aconitate 2-methyltransferase activity
KM547_RS17425	COG2076	Multidrug Resistance protein
KM547_RS17435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM547_RS17470	COG0531	amino acid
KM547_RS17480	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KM547_RS17480	COG5297	Belongs to the glycosyl hydrolase family 6
KM547_RS17485	COG0612	Peptidase, M16
KM547_RS17495	COG0741	lytic transglycosylase activity
KM547_RS17510	COG2207	Transcriptional regulator
KM547_RS17520	COG0598	Magnesium transport protein CorA
KM547_RS17525	COG1113	amino acid transport
KM547_RS17535	COG0697	spore germination
KM547_RS17545	COG0583	DNA-binding transcription factor activity
KM547_RS17565	COG2267	carboxylic ester hydrolase activity
KM547_RS17660	COG0464	growth
KM547_RS17670	COG0840	transmembrane signaling receptor activity
KM547_RS17710	COG2353	YceI-like domain
KM547_RS17740	COG0584	glycerophosphoryl diester phosphodiesterase
KM547_RS17755	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KM547_RS17775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KM547_RS17780	COG0459	protein refolding
KM547_RS17795	COG1324	tolerance protein
KM547_RS17805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM547_RS17815	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KM547_RS17820	COG0511	ligase activity, forming carbon-carbon bonds
KM547_RS17825	COG0439	Biotin carboxylase
KM547_RS17840	COG2264	protein methyltransferase activity
KM547_RS17860	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KM547_RS17905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM547_RS17910	COG0138	bifunctional purine biosynthesis protein purh
KM547_RS17915	COG0151	Belongs to the GarS family
KM547_RS17920	COG1289	transmembrane transporter activity
KM547_RS17925	COG2814	Major facilitator Superfamily
KM547_RS17960	COG2816	NAD+ diphosphatase activity
KM547_RS18000	COG2906	2 iron, 2 sulfur cluster binding
KM547_RS18030	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KM547_RS18045	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM547_RS18050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM547_RS18055	COG0730	response to heat
KM547_RS18060	COG4124	Belongs to the glycosyl hydrolase 26 family
KM547_RS18060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KM547_RS18070	COG0134	indole-3-glycerol-phosphate synthase activity
KM547_RS18075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM547_RS18095	COG1597	lipid kinase activity
KM547_RS18110	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KM547_RS18130	COG3179	chitinase
KM547_RS18140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM547_RS18145	COG2111	Na H antiporter
KM547_RS18145	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM547_RS18150	COG1006	Multisubunit Na H antiporter MnhC subunit
KM547_RS18155	COG0651	ATP synthesis coupled electron transport
KM547_RS18165	COG2212	antiporter activity
KM547_RS18170	COG1320	monovalent cation:proton antiporter activity
KM547_RS18175	COG0530	calcium, potassium:sodium antiporter activity
KM547_RS18190	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KM547_RS18215	COG3104	oligopeptide transport
KM547_RS18230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM547_RS18255	COG3227	Zinc metalloprotease (Elastase)
KM547_RS18260	COG0513	Belongs to the DEAD box helicase family
KM547_RS18275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM547_RS18280	COG1285	pathogenesis
KM547_RS18300	COG2354	Protein conserved in bacteria
KM547_RS18320	COG1196	nuclear chromosome segregation
KM547_RS18320	COG3264	Mechanosensitive ion channel
KM547_RS18325	COG3321	synthase
KM547_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS18325	COG0604	alcohol dehydrogenase
KM547_RS18345	COG1595	DNA-templated transcription, initiation
KM547_RS18360	COG1802	Transcriptional regulator
KM547_RS18375	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KM547_RS18410	COG1414	Transcriptional regulator
KM547_RS18415	COG0738	Major facilitator superfamily
KM547_RS18420	COG3254	rhamnose metabolic process
KM547_RS18430	COG4948	Mandelate Racemase Muconate Lactonizing
KM547_RS18435	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM547_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS18455	COG0546	phosphoglycolate phosphatase activity
KM547_RS18470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM547_RS18485	COG4807	Protein conserved in bacteria
KM547_RS18495	COG1418	mRNA catabolic process
KM547_RS18510	COG0708	Exodeoxyribonuclease III
KM547_RS18540	COG4773	Receptor
KM547_RS18565	COG3800	Transcriptional regulator
KM547_RS18565	COG1396	sequence-specific DNA binding
KM547_RS18585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM547_RS18590	COG1074	ATP-dependent DNA helicase activity
KM547_RS18595	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KM547_RS18600	COG1127	ABC transporter
KM547_RS18605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KM547_RS18610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KM547_RS18625	COG2853	Lipoprotein
KM547_RS18640	COG0386	Belongs to the glutathione peroxidase family
KM547_RS18645	COG1322	Protein conserved in bacteria
KM547_RS18660	COG1285	pathogenesis
KM547_RS18665	COG4191	Histidine kinase
KM547_RS18670	COG4566	intracellular signal transduction
KM547_RS18675	COG0531	amino acid
KM547_RS18685	COG1929	Belongs to the glycerate kinase type-1 family
KM547_RS18750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM547_RS18770	COG0628	permease
KM547_RS18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM547_RS18780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KM547_RS18790	COG0753	catalase activity
KM547_RS18800	COG2197	response regulator
KM547_RS18805	COG4585	Histidine kinase
KM547_RS18815	COG1131	(ABC) transporter
KM547_RS18825	COG1136	(ABC) transporter
KM547_RS18830	COG0577	efflux transmembrane transporter activity
KM547_RS18845	COG2962	Rard protein
KM547_RS18850	COG0697	spore germination
KM547_RS18865	COG0180	Tryptophanyl-tRNA synthetase
KM547_RS18875	COG3237	CsbD-like
KM547_RS18905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KM547_RS18910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KM547_RS18910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KM547_RS18920	COG3228	Belongs to the MtfA family
KM547_RS18950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM547_RS18975	COG2084	Dehydrogenase
KM547_RS18980	COG1902	pentaerythritol trinitrate reductase activity
KM547_RS18990	COG2814	Major facilitator Superfamily
KM547_RS18995	COG0583	DNA-binding transcription factor activity
KM547_RS19015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM547_RS19020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM547_RS19025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM547_RS19030	COG1764	response to oxidative stress
KM547_RS19035	COG1846	Transcriptional regulator
KM547_RS19045	COG1028	Short-chain dehydrogenase reductase Sdr
KM547_RS19055	COG0463	Glycosyl transferase, family 2
KM547_RS19065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM547_RS19070	COG3100	YcgL domain-containing protein
KM547_RS19105	COG0745	RESPONSE REGULATOR receiver
KM547_RS19115	COG3387	PFAM Glycoside hydrolase 15-related
KM547_RS19120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM547_RS19140	COG1278	Cold shock
KM547_RS19155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM547_RS19160	COG1960	acyl-CoA dehydrogenase activity
KM547_RS19170	COG3245	cytochrome
KM547_RS19180	COG1742	UPF0060 membrane protein
KM547_RS19195	COG0697	spore germination
KM547_RS19205	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KM547_RS19230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM547_RS19245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM547_RS19265	COG1294	oxidase, subunit
KM547_RS19270	COG1271	oxidase subunit
KM547_RS19285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM547_RS19290	COG0408	coproporphyrinogen oxidase activity
KM547_RS19300	COG2323	membrane
KM547_RS19305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM547_RS19305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM547_RS19320	COG0589	response to stress
KM547_RS19335	COG0210	DNA helicase
KM547_RS19400	COG0463	Glycosyl transferase, family 2
KM547_RS19410	COG1475	DNA binding
KM547_RS19415	COG1192	Involved in chromosome partitioning
KM547_RS19420	COG0357	Ribosomal RNA small subunit methyltransferase G
KM547_RS19425	COG2091	lysine biosynthetic process via aminoadipic acid
KM547_RS19450	COG0477	Major facilitator Superfamily
KM547_RS19480	COG1971	Probably functions as a manganese efflux pump
KM547_RS19485	COG2205	protein histidine kinase activity
KM547_RS19490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM547_RS19495	COG3459	Glycosyltransferase 36 associated
KM547_RS19500	COG2211	Major facilitator Superfamily
KM547_RS19505	COG3265	gluconokinase activity
KM547_RS19535	COG2911	Protein conserved in bacteria
KM547_RS19540	COG0729	surface antigen
KM547_RS19560	COG3132	Protein of unknown function, DUF480
KM547_RS19585	COG0284	orotidine-5'-phosphate decarboxylase activity
KM547_RS19600	COG1609	Transcriptional regulator
KM547_RS19610	COG2937	Belongs to the GPAT DAPAT family
KM547_RS19635	COG2211	Major facilitator Superfamily
KM547_RS19650	COG3693	PFAM glycoside hydrolase, family 10
KM547_RS19655	COG1904	glucuronate isomerase
KM547_RS19690	COG0246	Mannitol dehydrogenase
KM547_RS19695	COG1472	Belongs to the glycosyl hydrolase 3 family
KM547_RS19705	COG4948	Mandelate Racemase Muconate Lactonizing
KM547_RS19715	COG3661	Belongs to the glycosyl hydrolase 67 family
KM547_RS19725	COG2115	Belongs to the xylose isomerase family
KM547_RS19730	COG0037	tRNA processing
KM547_RS19750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM547_RS19760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KM547_RS19770	COG0805	protein transport
KM547_RS19780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KM547_RS19780	COG0519	Catalyzes the synthesis of GMP from XMP
KM547_RS19785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM547_RS19800	COG0210	DNA helicase
KM547_RS19805	COG1435	thymidine kinase activity
KM547_RS19815	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KM547_RS19825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KM547_RS19850	COG0706	membrane insertase activity
KM547_RS19855	COG0594	ribonuclease P activity