locus-tag	class	description
KCU58_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCU58_RS00020	COG0187	DNA topoisomerase II activity
KCU58_RS00025	COG1266	CAAX protease self-immunity
KCU58_RS00030	COG0501	Belongs to the peptidase M48B family
KCU58_RS00070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCU58_RS00085	COG1280	lysine exporter protein (LysE YggA)
KCU58_RS00100	COG4772	TonB-dependent receptor
KCU58_RS00110	COG3284	Transcriptional regulator
KCU58_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_RS00150	COG1304	FMN binding
KCU58_RS00185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU58_RS00265	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCU58_RS00285	COG4771	TonB-dependent receptor
KCU58_RS00330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KCU58_RS00345	COG3507	Belongs to the glycosyl hydrolase 43 family
KCU58_RS00350	COG1609	Transcriptional regulator
KCU58_RS00360	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS00375	COG3186	Phenylalanine-4-hydroxylase
KCU58_RS00380	COG1522	sequence-specific DNA binding
KCU58_RS00400	COG1752	Esterase of the alpha-beta hydrolase superfamily
KCU58_RS00405	COG1473	amidohydrolase
KCU58_RS00410	COG1473	amidohydrolase
KCU58_RS00425	COG0671	phosphoesterase, PA-phosphatase related
KCU58_RS00440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KCU58_RS00475	COG1929	Belongs to the glycerate kinase type-1 family
KCU58_RS00485	COG0531	amino acid
KCU58_RS00490	COG4566	intracellular signal transduction
KCU58_RS00495	COG4191	Histidine kinase
KCU58_RS00515	COG1322	Protein conserved in bacteria
KCU58_RS00520	COG0386	Belongs to the glutathione peroxidase family
KCU58_RS00525	COG2853	Lipoprotein
KCU58_RS00540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCU58_RS00545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCU58_RS00550	COG1127	ABC transporter
KCU58_RS00555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KCU58_RS00560	COG1074	ATP-dependent DNA helicase activity
KCU58_RS00565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KCU58_RS00585	COG0537	adenosine 5'-monophosphoramidase activity
KCU58_RS00650	COG0477	Major facilitator Superfamily
KCU58_RS00655	COG0302	gtp cyclohydrolase
KCU58_RS00680	COG0730	response to heat
KCU58_RS00695	COG2951	lytic endotransglycosylase activity
KCU58_RS00755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_RS00760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_RS00765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_RS00770	COG0493	'glutamate synthase
KCU58_RS00775	COG0067	glutamate synthase
KCU58_RS00775	COG0069	glutamate synthase activity
KCU58_RS00775	COG0070	glutamate synthase
KCU58_RS00820	COG1111	helicase
KCU58_RS00820	COG1205	dead DEAH box helicase
KCU58_RS00850	COG2271	Major facilitator Superfamily
KCU58_RS00905	COG1192	Involved in chromosome partitioning
KCU58_RS00910	COG2062	phosphohistidine phosphatase, SixA
KCU58_RS00920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCU58_RS00925	COG2050	protein possibly involved in aromatic compounds catabolism
KCU58_RS00935	COG2267	carboxylic ester hydrolase activity
KCU58_RS00950	COG1881	PFAM PEBP family protein
KCU58_RS00955	COG1968	undecaprenyl-diphosphatase activity
KCU58_RS00960	COG0174	glutamine synthetase
KCU58_RS00965	COG0347	Belongs to the P(II) protein family
KCU58_RS00970	COG0004	ammonium transporteR
KCU58_RS00975	COG3852	Histidine kinase
KCU58_RS00980	COG2204	response regulator
KCU58_RS00985	COG2032	superoxide dismutase activity
KCU58_RS00990	COG2032	superoxide dismutase activity
KCU58_RS01000	COG0183	Belongs to the thiolase family
KCU58_RS01040	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KCU58_RS01045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KCU58_RS01055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KCU58_RS01065	COG0612	Peptidase, M16
KCU58_RS01075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_RS01085	COG0596	Alpha beta hydrolase
KCU58_RS01095	COG0727	PFAM Uncharacterised protein family (UPF0153)
KCU58_RS01100	COG0318	PFAM AMP-dependent synthetase and ligase
KCU58_RS01115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU58_RS01125	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCU58_RS01140	COG4232	protein-disulfide reductase activity
KCU58_RS01145	COG0564	pseudouridine synthase activity
KCU58_RS01165	COG0339	signal peptide processing
KCU58_RS01185	COG0583	DNA-binding transcription factor activity
KCU58_RS01190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KCU58_RS01195	COG2224	Isocitrate lyase
KCU58_RS01230	COG0659	secondary active sulfate transmembrane transporter activity
KCU58_RS01265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU58_RS01270	COG2130	NADP-dependent
KCU58_RS01285	COG1187	pseudouridine synthase activity
KCU58_RS01300	COG1643	Atp-dependent helicase
KCU58_RS01305	COG0084	hydrolase, TatD family'
KCU58_RS01320	COG0842	Transport permease protein
KCU58_RS01325	COG1131	(ABC) transporter
KCU58_RS01330	COG0633	Ferredoxin
KCU58_RS01330	COG0543	2 iron, 2 sulfur cluster binding
KCU58_RS01340	COG1476	TRANSCRIPTIONal
KCU58_RS01350	COG4555	ABC transporter
KCU58_RS01370	COG0625	glutathione transferase activity
KCU58_RS01445	COG1199	ATP-dependent helicase activity
KCU58_RS01505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU58_RS01530	COG0628	permease
KCU58_RS01540	COG2133	pyrroloquinoline quinone binding
KCU58_RS01590	COG0754	glutathionylspermidine amidase activity
KCU58_RS01600	COG0714	Associated with various cellular activities
KCU58_RS01645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCU58_RS01660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_RS01665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU58_RS01690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCU58_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS01725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCU58_RS01735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCU58_RS01765	COG0606	chelatase, subunit chli
KCU58_RS01770	COG2960	long-chain fatty acid transporting porin activity
KCU58_RS01800	COG1166	arginine decarboxylase activity
KCU58_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KCU58_RS01820	COG2755	lipolytic protein G-D-S-L family
KCU58_RS01820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KCU58_RS01825	COG0583	DNA-binding transcription factor activity
KCU58_RS01845	COG4221	oxidoreductase activity
KCU58_RS01865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCU58_RS01885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCU58_RS01895	COG2814	Major facilitator Superfamily
KCU58_RS01905	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KCU58_RS01910	COG0739	heme binding
KCU58_RS01915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCU58_RS01945	COG1064	alcohol dehydrogenase
KCU58_RS01950	COG2234	aminopeptidase activity
KCU58_RS01960	COG4942	peptidase
KCU58_RS01965	COG0793	Belongs to the peptidase S41A family
KCU58_RS02005	COG0531	amino acid
KCU58_RS02025	COG1565	acr, cog1565
KCU58_RS02025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KCU58_RS02030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCU58_RS02035	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KCU58_RS02065	COG0109	protoheme IX farnesyltransferase activity
KCU58_RS02080	COG0358	DNA primase activity
KCU58_RS02085	COG1295	ribonuclease BN
KCU58_RS02105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCU58_RS02110	COG2308	Evidence 4 Homologs of previously reported genes of
KCU58_RS02125	COG2133	pyrroloquinoline quinone binding
KCU58_RS02145	COG0531	amino acid
KCU58_RS02155	COG4948	Mandelate Racemase Muconate Lactonizing
KCU58_RS02165	COG4771	TonB-dependent receptor
KCU58_RS02170	COG3023	N-Acetylmuramoyl-L-alanine amidase
KCU58_RS02220	COG5383	Protein conserved in bacteria
KCU58_RS02235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU58_RS02240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_RS02255	COG1652	LysM domain
KCU58_RS02265	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCU58_RS02270	COG1518	maintenance of DNA repeat elements
KCU58_RS02320	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KCU58_RS02330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCU58_RS02335	COG3118	belongs to the thioredoxin family
KCU58_RS02345	COG2884	Cell division ATP-binding protein ftsE
KCU58_RS02350	COG2177	Part of the ABC transporter FtsEX involved in
KCU58_RS02355	COG2201	protein-glutamate methylesterase activity
KCU58_RS02360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCU58_RS02365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCU58_RS02375	COG1252	NADH dehydrogenase
KCU58_RS02385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCU58_RS02395	COG0534	Mate efflux family protein
KCU58_RS02400	COG0616	signal peptide processing
KCU58_RS02410	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS02425	COG0009	L-threonylcarbamoyladenylate synthase
KCU58_RS02430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCU58_RS02430	COG1754	DNA topoisomerase type I activity
KCU58_RS02435	COG1714	RDD family
KCU58_RS02455	COG0758	DNA mediated transformation
KCU58_RS02460	COG1652	LysM domain
KCU58_RS02465	COG0242	peptide deformylase activity
KCU58_RS02470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCU58_RS02475	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCU58_RS02475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCU58_RS02480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCU58_RS02515	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCU58_RS02520	COG1247	-acetyltransferase
KCU58_RS02530	COG1490	D-aminoacyl-tRNA deacylase activity
KCU58_RS02535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCU58_RS02570	COG1609	Transcriptional regulator
KCU58_RS02580	COG0366	Alpha amylase catalytic
KCU58_RS02585	COG0366	Alpha amylase catalytic
KCU58_RS02635	COG1309	transcriptional regulator
KCU58_RS02685	COG0840	transmembrane signaling receptor activity
KCU58_RS02700	COG3546	catalase activity
KCU58_RS02705	COG3685	Protein conserved in bacteria
KCU58_RS02710	COG3685	Protein conserved in bacteria
KCU58_RS02715	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS02725	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KCU58_RS02740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCU58_RS02755	COG0028	Belongs to the TPP enzyme family
KCU58_RS02760	COG4191	Histidine kinase
KCU58_RS02765	COG2204	response regulator
KCU58_RS02795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KCU58_RS02800	COG0732	type I restriction modification DNA specificity domain
KCU58_RS02825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCU58_RS02825	COG1648	precorrin-2 dehydrogenase activity
KCU58_RS02835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KCU58_RS02835	COG1116	anion transmembrane transporter activity
KCU58_RS02840	COG2223	nitrite transmembrane transporter activity
KCU58_RS02845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCU58_RS02850	COG2146	nitrite reductase [NAD(P)H] activity
KCU58_RS02855	COG0243	molybdopterin cofactor binding
KCU58_RS02880	COG1640	4-alpha-glucanotransferase
KCU58_RS02885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCU58_RS02905	COG0745	RESPONSE REGULATOR receiver
KCU58_RS02930	COG0181	hydroxymethylbilane synthase activity
KCU58_RS02945	COG1733	regulation of RNA biosynthetic process
KCU58_RS02960	COG1505	serine-type exopeptidase activity
KCU58_RS02965	COG0436	Aminotransferase
KCU58_RS02975	COG2832	Protein of unknown function (DUF454)
KCU58_RS02985	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCU58_RS03005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCU58_RS03030	COG2226	methyltransferase
KCU58_RS03035	COG0308	aminopeptidase N
KCU58_RS03040	COG0596	Alpha beta hydrolase
KCU58_RS03040	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU58_RS03060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU58_RS03065	COG1077	Cell shape determining protein MreB Mrl
KCU58_RS03080	COG0768	penicillin binding
KCU58_RS03085	COG0772	Belongs to the SEDS family
KCU58_RS03100	COG2951	lytic endotransglycosylase activity
KCU58_RS03110	COG1686	Belongs to the peptidase S11 family
KCU58_RS03145	COG0321	lipoyl(octanoyl) transferase activity
KCU58_RS03150	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KCU58_RS03175	COG1051	belongs to the nudix hydrolase family
KCU58_RS03175	COG1056	cytidyltransferase-related domain
KCU58_RS03210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KCU58_RS03215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCU58_RS03220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KCU58_RS03225	COG1561	YicC-like family, N-terminal region
KCU58_RS03230	COG0194	GDP metabolic process
KCU58_RS03235	COG1758	RNA polymerase activity
KCU58_RS03240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCU58_RS03265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCU58_RS03275	COG0254	rRNA binding
KCU58_RS03280	COG0372	Belongs to the citrate synthase family
KCU58_RS03295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCU58_RS03315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCU58_RS03320	COG0667	Aldo Keto reductase
KCU58_RS03330	COG4771	TonB-dependent receptor
KCU58_RS03350	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KCU58_RS03355	COG4181	ATPase activity
KCU58_RS03370	COG0642	Histidine kinase
KCU58_RS03380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KCU58_RS03385	COG0861	Integral membrane protein TerC family
KCU58_RS03390	COG1704	LemA family
KCU58_RS03435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KCU58_RS03445	COG1215	transferase activity, transferring glycosyl groups
KCU58_RS03470	COG0242	peptide deformylase activity
KCU58_RS03480	COG0488	(ABC) transporter
KCU58_RS03485	COG0477	Major facilitator Superfamily
KCU58_RS03515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCU58_RS03525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCU58_RS03525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCU58_RS03540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KCU58_RS03545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCU58_RS03550	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KCU58_RS03575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KCU58_RS03580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KCU58_RS03590	COG2205	protein histidine kinase activity
KCU58_RS03595	COG0745	RESPONSE REGULATOR receiver
KCU58_RS03600	COG0277	FAD linked oxidase domain protein
KCU58_RS03610	COG0792	nuclease activity
KCU58_RS03645	COG2001	Belongs to the MraZ family
KCU58_RS03650	COG0275	rRNA processing
KCU58_RS03655	COG3116	cell division
KCU58_RS03670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCU58_RS03695	COG1181	Belongs to the D-alanine--D-alanine ligase family
KCU58_RS03700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KCU58_RS03710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCU58_RS03715	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KCU58_RS03725	COG0739	heme binding
KCU58_RS03740	COG0494	nUDIX hydrolase
KCU58_RS03750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KCU58_RS03775	COG2226	methyltransferase
KCU58_RS03815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCU58_RS03830	COG1090	epimerase
KCU58_RS03845	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KCU58_RS03850	COG0673	inositol 2-dehydrogenase activity
KCU58_RS03855	COG2823	Periplasmic or secreted lipoprotein
KCU58_RS03865	COG2202	Pas domain
KCU58_RS03865	COG2205	protein histidine kinase activity
KCU58_RS03870	COG0784	Response regulator, receiver
KCU58_RS03875	COG4191	Histidine kinase
KCU58_RS03885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCU58_RS03925	COG3250	beta-galactosidase activity
KCU58_RS03940	COG2188	Transcriptional regulator
KCU58_RS03945	COG0738	Major facilitator superfamily
KCU58_RS03950	COG1609	Transcriptional regulator
KCU58_RS03955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCU58_RS03960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCU58_RS03965	COG0617	tRNA 3'-terminal CCA addition
KCU58_RS04040	COG2205	protein histidine kinase activity
KCU58_RS04055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KCU58_RS04060	COG3791	Glutathione-dependent formaldehyde-activating
KCU58_RS04070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCU58_RS04100	COG0804	urea catabolic process
KCU58_RS04105	COG1228	amidohydrolase
KCU58_RS04125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCU58_RS04150	COG0436	Aminotransferase
KCU58_RS04155	COG1162	GTPase activity
KCU58_RS04180	COG2211	Major facilitator Superfamily
KCU58_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS04195	COG2851	Citrate transporter
KCU58_RS04210	COG0642	Histidine kinase
KCU58_RS04230	COG4191	Histidine kinase
KCU58_RS04240	COG1301	dicarboxylic acid transport
KCU58_RS04245	COG0280	phosphate acetyltransferase
KCU58_RS04245	COG0281	malic enzyme
KCU58_RS04335	COG1560	Kdo2-lipid A biosynthetic process
KCU58_RS04340	COG1519	Transferase
KCU58_RS04345	COG1538	Outer membrane efflux protein
KCU58_RS04350	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KCU58_RS04360	COG3706	GGDEF domain
KCU58_RS04365	COG0473	3-isopropylmalate dehydrogenase activity
KCU58_RS04370	COG0066	3-isopropylmalate dehydratase activity
KCU58_RS04380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCU58_RS04390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCU58_RS04410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCU58_RS04415	COG0840	transmembrane signaling receptor activity
KCU58_RS04440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KCU58_RS04450	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KCU58_RS04475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KCU58_RS04485	COG0671	phosphoesterase, PA-phosphatase related
KCU58_RS04500	COG1940	carbohydrate kinase activity
KCU58_RS04510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU58_RS04520	COG2010	Cytochrome c
KCU58_RS04550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KCU58_RS04565	COG1773	rubredoxin
KCU58_RS04580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCU58_RS04590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCU58_RS04615	COG3079	Belongs to the UPF0149 family
KCU58_RS04620	COG0006	proline dipeptidase activity
KCU58_RS04640	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KCU58_RS04670	COG0714	Associated with various cellular activities
KCU58_RS04700	COG1301	dicarboxylic acid transport
KCU58_RS04705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCU58_RS04730	COG0739	heme binding
KCU58_RS04735	COG1376	ErfK ybiS ycfS ynhG family protein
KCU58_RS04760	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KCU58_RS04765	COG4149	molybdate abc transporter
KCU58_RS04770	COG0725	ABC transporter, periplasmic molybdate-binding protein
KCU58_RS04780	COG0640	Transcriptional regulator
KCU58_RS04800	COG3047	cAMP biosynthetic process
KCU58_RS04805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KCU58_RS04850	COG0469	pyruvate kinase activity
KCU58_RS04855	COG3588	fructose-bisphosphate aldolase
KCU58_RS04860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KCU58_RS04900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCU58_RS04915	COG1648	precorrin-2 dehydrogenase activity
KCU58_RS04915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KCU58_RS04930	COG2198	Histidine kinase
KCU58_RS04930	COG2205	protein histidine kinase activity
KCU58_RS04930	COG0784	Response regulator, receiver
KCU58_RS04935	COG1393	Belongs to the ArsC family
KCU58_RS04965	COG0175	sulfate reduction
KCU58_RS04970	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KCU58_RS04975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCU58_RS04985	COG0529	Catalyzes the synthesis of activated sulfate
KCU58_RS04985	COG2895	sulfate adenylyltransferase (ATP) activity
KCU58_RS04990	COG0840	transmembrane signaling receptor activity
KCU58_RS05030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCU58_RS05050	COG1609	Transcriptional regulator
KCU58_RS05065	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCU58_RS05080	COG0471	metal ion transport
KCU58_RS05080	COG3273	potassium ion transport
KCU58_RS05090	COG2022	thiamine diphosphate biosynthetic process
KCU58_RS05115	COG0174	glutamine synthetase
KCU58_RS05120	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KCU58_RS05130	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCU58_RS05145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KCU58_RS05165	COG3511	phospholipase C
KCU58_RS05175	COG0189	ligase activity
KCU58_RS05185	COG0745	RESPONSE REGULATOR receiver
KCU58_RS05200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KCU58_RS05255	COG4993	Dehydrogenase
KCU58_RS05270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KCU58_RS05270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCU58_RS05280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KCU58_RS05295	COG1174	glycine betaine transport
KCU58_RS05300	COG1125	glycine betaine transport
KCU58_RS05310	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU58_RS05315	COG0564	pseudouridine synthase activity
KCU58_RS05335	COG4993	Dehydrogenase
KCU58_RS05350	COG3387	PFAM Glycoside hydrolase 15-related
KCU58_RS05375	COG0454	-acetyltransferase
KCU58_RS05400	COG0542	response to heat
KCU58_RS05425	COG0019	diaminopimelate decarboxylase activity
KCU58_RS05430	COG4264	IucA IucC family
KCU58_RS05435	COG2814	Major facilitator Superfamily
KCU58_RS05440	COG4264	IucA IucC family
KCU58_RS05450	COG4772	TonB-dependent receptor
KCU58_RS05460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCU58_RS05460	COG4651	solute:proton antiporter activity
KCU58_RS05515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_RS05515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_RS05535	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KCU58_RS05575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KCU58_RS05580	COG1404	Belongs to the peptidase S8 family
KCU58_RS05615	COG1295	ribonuclease BN
KCU58_RS05620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCU58_RS05640	COG0521	Mo-molybdopterin cofactor biosynthetic process
KCU58_RS05740	COG3209	COG3209 Rhs family protein
KCU58_RS05760	COG3209	COG3209 Rhs family protein
KCU58_RS05815	COG4682	membrane
KCU58_RS05905	COG3179	chitinase
KCU58_RS06065	COG3537	Alpha-1,2-mannosidase
KCU58_RS06085	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_RS06095	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KCU58_RS06100	COG3858	chitin binding
KCU58_RS06100	COG1388	LysM domain
KCU58_RS06120	COG0837	glucose binding
KCU58_RS06130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KCU58_RS06140	COG0494	nUDIX hydrolase
KCU58_RS06145	COG1218	3'(2'),5'-bisphosphate nucleotidase
KCU58_RS06150	COG3956	TIGRFAM MazG family protein
KCU58_RS06155	COG1742	UPF0060 membrane protein
KCU58_RS06165	COG0330	HflC and HflK could
KCU58_RS06235	COG2124	cytochrome p450
KCU58_RS06240	COG2124	cytochrome p450
KCU58_RS06245	COG1141	Ferredoxin
KCU58_RS06250	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS06255	COG2124	cytochrome p450
KCU58_RS06260	COG0142	geranyltranstransferase activity
KCU58_RS06265	COG1657	PFAM Prenyltransferase squalene oxidase
KCU58_RS06275	COG1304	FMN binding
KCU58_RS06310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCU58_RS06315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCU58_RS06320	COG0463	Glycosyl transferase, family 2
KCU58_RS06325	COG0517	IMP dehydrogenase activity
KCU58_RS06330	COG2982	Protein involved in outer membrane biogenesis
KCU58_RS06335	COG1272	protein, Hemolysin III
KCU58_RS06340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCU58_RS06350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU58_RS06355	COG0626	cystathionine gamma-synthase activity
KCU58_RS06360	COG0460	homoserine dehydrogenase
KCU58_RS06360	COG0527	aspartate kinase activity
KCU58_RS06365	COG2267	carboxylic ester hydrolase activity
KCU58_RS06375	COG1760	l-serine dehydratase
KCU58_RS06390	COG3038	cytochrome b561
KCU58_RS06410	COG2814	Major facilitator Superfamily
KCU58_RS06415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCU58_RS06425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_RS06445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCU58_RS06450	COG0259	pyridoxamine-phosphate oxidase activity
KCU58_RS06505	COG0519	Catalyzes the synthesis of GMP from XMP
KCU58_RS06520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCU58_RS06545	COG0840	transmembrane signaling receptor activity
KCU58_RS06555	COG1113	amino acid transport
KCU58_RS06575	COG2239	Acts as a magnesium transporter
KCU58_RS06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCU58_RS06585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU58_RS06595	COG1660	Displays ATPase and GTPase activities
KCU58_RS06605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU58_RS06620	COG1137	ATPase activity
KCU58_RS06635	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KCU58_RS06680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCU58_RS06705	COG0628	permease
KCU58_RS06715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KCU58_RS06720	COG3178	'Phosphotransferase
KCU58_RS06735	COG1555	photosystem II stabilization
KCU58_RS06755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCU58_RS06760	COG1477	protein flavinylation
KCU58_RS06785	COG4774	siderophore transport
KCU58_RS06790	COG2146	nitrite reductase [NAD(P)H] activity
KCU58_RS06800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCU58_RS06805	COG0719	Fe-S assembly protein
KCU58_RS06810	COG0396	ATPase activity
KCU58_RS06815	COG0719	Fe-S assembly protein
KCU58_RS06830	COG0693	protein deglycase activity
KCU58_RS06845	COG0739	heme binding
KCU58_RS06860	COG1764	response to oxidative stress
KCU58_RS06870	COG0384	phenazine biosynthesis protein PhzF
KCU58_RS06875	COG0527	aspartate kinase activity
KCU58_RS06900	COG0142	geranyltranstransferase activity
KCU58_RS06905	COG0629	single-stranded DNA binding
KCU58_RS06910	COG3550	peptidyl-serine autophosphorylation
KCU58_RS06925	COG3104	oligopeptide transport
KCU58_RS06930	COG1297	OPT oligopeptide transporter protein
KCU58_RS06935	COG1506	peptidase
KCU58_RS06935	COG0823	Involved in the tonB-independent uptake of proteins
KCU58_RS06960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCU58_RS06965	COG2879	small protein
KCU58_RS06970	COG1966	Carbon starvation protein
KCU58_RS07005	COG2211	Major facilitator Superfamily
KCU58_RS07015	COG2801	Transposase and inactivated derivatives
KCU58_RS07040	COG0835	chemotaxis
KCU58_RS07045	COG0840	transmembrane signaling receptor activity
KCU58_RS07050	COG0840	transmembrane signaling receptor activity
KCU58_RS07060	COG0643	Histidine kinase
KCU58_RS07060	COG2198	Histidine kinase
KCU58_RS07070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCU58_RS07090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KCU58_RS07100	COG2205	protein histidine kinase activity
KCU58_RS07135	COG0735	belongs to the Fur family
KCU58_RS07175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KCU58_RS07180	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KCU58_RS07185	COG2080	2 iron, 2 sulfur cluster binding
KCU58_RS07295	COG1187	pseudouridine synthase activity
KCU58_RS07320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KCU58_RS07340	COG1132	(ABC) transporter
KCU58_RS07380	COG1061	Type III restriction enzyme res subunit
KCU58_RS07450	COG1981	membrane
KCU58_RS07475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_RS07480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_RS07490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_RS07500	COG0750	zinc metalloprotease
KCU58_RS07505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KCU58_RS07510	COG0575	Belongs to the CDS family
KCU58_RS07515	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCU58_RS07525	COG0528	UMP kinase activity
KCU58_RS07535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCU58_RS07575	COG0024	Methionine aminopeptidase
KCU58_RS07590	COG1393	Belongs to the ArsC family
KCU58_RS07595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCU58_RS07605	COG0367	asparagine synthase
KCU58_RS07645	COG1566	PFAM secretion protein HlyD family protein
KCU58_RS07650	COG2814	Major facilitator Superfamily
KCU58_RS07685	COG0557	exoribonuclease II activity
KCU58_RS07695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCU58_RS07715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KCU58_RS07735	COG0704	Plays a role in the regulation of phosphate uptake
KCU58_RS07745	COG0581	inorganic phosphate transmembrane transporter activity
KCU58_RS07755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCU58_RS07760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KCU58_RS07780	COG0659	secondary active sulfate transmembrane transporter activity
KCU58_RS07790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCU58_RS07800	COG1024	Enoyl-CoA hydratase
KCU58_RS07860	COG2205	protein histidine kinase activity
KCU58_RS07860	COG5002	protein histidine kinase activity
KCU58_RS07860	COG0784	Response regulator, receiver
KCU58_RS07865	COG2733	membrane
KCU58_RS07885	COG0686	Belongs to the AlaDH PNT family
KCU58_RS07890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KCU58_RS07895	COG1396	sequence-specific DNA binding
KCU58_RS07895	COG1917	Cupin 2, conserved barrel domain protein
KCU58_RS07900	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_RS07925	COG2223	nitrite transmembrane transporter activity
KCU58_RS07935	COG0243	molybdopterin cofactor binding
KCU58_RS07955	COG0477	Major facilitator Superfamily
KCU58_RS07965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_RS07970	COG0174	glutamine synthetase
KCU58_RS07975	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KCU58_RS07980	COG0174	glutamine synthetase
KCU58_RS07995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KCU58_RS08015	COG3842	ATPase activity
KCU58_RS08020	COG1176	ABC-type spermidine putrescine transport system, permease component I
KCU58_RS08025	COG1177	transmembrane transport
KCU58_RS08030	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_RS08045	COG4535	Mg2 and Co2 transporter CorC
KCU58_RS08060	COG1702	phosphate starvation-inducible protein PhoH
KCU58_RS08075	COG0741	lytic transglycosylase activity
KCU58_RS08080	COG0723	plastoquinol--plastocyanin reductase activity
KCU58_RS08085	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KCU58_RS08095	COG2857	Cytochrome c1
KCU58_RS08100	COG0625	glutathione transferase activity
KCU58_RS08105	COG2969	positive regulation of protein catabolic process
KCU58_RS08145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KCU58_RS08150	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS08155	COG2095	MarC family integral membrane protein
KCU58_RS08165	COG1611	Belongs to the LOG family
KCU58_RS08170	COG3275	phosphorelay sensor kinase activity
KCU58_RS08215	COG0556	nucleotide-excision repair
KCU58_RS08235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCU58_RS08240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_RS08250	COG2902	Dehydrogenase
KCU58_RS08310	COG2925	Exonuclease
KCU58_RS08320	COG3844	kynureninase activity
KCU58_RS08330	COG0662	Cupin 2, conserved barrel domain protein
KCU58_RS08335	COG0288	reversible hydration of carbon dioxide
KCU58_RS08380	COG2197	response regulator
KCU58_RS08405	COG0316	Belongs to the HesB IscA family
KCU58_RS08440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCU58_RS08445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCU58_RS08450	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KCU58_RS08460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KCU58_RS08480	COG1309	transcriptional regulator
KCU58_RS08495	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCU58_RS08510	COG1228	amidohydrolase
KCU58_RS08525	COG4221	oxidoreductase activity
KCU58_RS08565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCU58_RS08570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCU58_RS08575	COG1605	Chorismate mutase
KCU58_RS08575	COG0077	Prephenate dehydratase
KCU58_RS08600	COG0583	DNA-binding transcription factor activity
KCU58_RS08650	COG0577	efflux transmembrane transporter activity
KCU58_RS08650	COG1136	(ABC) transporter
KCU58_RS08680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCU58_RS08680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KCU58_RS08685	COG1105	Belongs to the carbohydrate kinase PfkB family
KCU58_RS08690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCU58_RS08690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KCU58_RS08695	COG1609	Transcriptional regulator
KCU58_RS08705	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KCU58_RS08710	COG0069	glutamate synthase activity
KCU58_RS08745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCU58_RS08760	COG1253	flavin adenine dinucleotide binding
KCU58_RS08770	COG0306	phosphate transporter
KCU58_RS08815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KCU58_RS08820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KCU58_RS08835	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KCU58_RS08845	COG1238	metal cluster binding
KCU58_RS08860	COG1534	Rna-binding protein
KCU58_RS08865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KCU58_RS08870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCU58_RS08875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCU58_RS08880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCU58_RS08890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCU58_RS08895	COG1546	Belongs to the CinA family
KCU58_RS08900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KCU58_RS08905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCU58_RS08910	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCU58_RS08915	COG2137	regulation of response to DNA damage stimulus
KCU58_RS08925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCU58_RS08955	COG1741	Belongs to the pirin family
KCU58_RS08960	COG0583	DNA-binding transcription factor activity
KCU58_RS08980	COG0351	phosphomethylpyrimidine kinase
KCU58_RS08980	COG0352	thiamine-phosphate diphosphorylase activity
KCU58_RS09020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KCU58_RS09025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCU58_RS09035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCU58_RS09045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KCU58_RS09050	COG3734	2-keto-3-deoxy-galactonokinase
KCU58_RS09065	COG0800	Aldolase
KCU58_RS09100	COG0784	Response regulator, receiver
KCU58_RS09100	COG2198	Histidine kinase
KCU58_RS09100	COG2205	protein histidine kinase activity
KCU58_RS09105	COG1024	Enoyl-CoA hydratase
KCU58_RS09110	COG0318	PFAM AMP-dependent synthetase and ligase
KCU58_RS09175	COG0840	transmembrane signaling receptor activity
KCU58_RS09185	COG0840	transmembrane signaling receptor activity
KCU58_RS09195	COG0835	chemotaxis
KCU58_RS09205	COG0840	transmembrane signaling receptor activity
KCU58_RS09215	COG0840	transmembrane signaling receptor activity
KCU58_RS09220	COG0840	transmembrane signaling receptor activity
KCU58_RS09225	COG0840	transmembrane signaling receptor activity
KCU58_RS09235	COG0840	transmembrane signaling receptor activity
KCU58_RS09245	COG0840	transmembrane signaling receptor activity
KCU58_RS09250	COG0840	transmembrane signaling receptor activity
KCU58_RS09260	COG0840	transmembrane signaling receptor activity
KCU58_RS09265	COG0840	transmembrane signaling receptor activity
KCU58_RS09280	COG0745	RESPONSE REGULATOR receiver
KCU58_RS09290	COG0835	chemotaxis
KCU58_RS09295	COG1192	Involved in chromosome partitioning
KCU58_RS09305	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KCU58_RS09310	COG0643	Histidine kinase
KCU58_RS09310	COG0784	Response regulator, receiver
KCU58_RS09310	COG2198	Histidine kinase
KCU58_RS09315	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KCU58_RS09360	COG1684	flagellar biosynthetic protein fliR
KCU58_RS09365	COG1987	bacterial-type flagellum assembly
KCU58_RS09375	COG3190	flagellar
KCU58_RS09425	COG1677	Flagellar hook-basal body complex protein FliE
KCU58_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS09470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_RS09490	COG2201	protein-glutamate methylesterase activity
KCU58_RS09500	COG2197	response regulator
KCU58_RS09520	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCU58_RS09525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCU58_RS09535	COG1256	bacterial-type flagellum assembly
KCU58_RS09535	COG4786	Flagellar basal body rod
KCU58_RS09535	COG1256	bacterial-type flagellum assembly
KCU58_RS09535	COG4786	Flagellar basal body rod
KCU58_RS09550	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KCU58_RS09565	COG1749	Flagellar hook protein flgE
KCU58_RS09575	COG1558	bacterial-type flagellum-dependent cell motility
KCU58_RS09585	COG0835	chemotaxis
KCU58_RS09585	COG0784	Response regulator, receiver
KCU58_RS09645	COG2915	High frequency lysogenization protein hflD homolog
KCU58_RS09650	COG0482	sulfurtransferase activity
KCU58_RS09670	COG0542	response to heat
KCU58_RS09680	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KCU58_RS09690	COG0492	ferredoxin-NADP+ reductase activity
KCU58_RS09695	COG1674	ftsk spoiiie
KCU58_RS09715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KCU58_RS09720	COG0038	chloride channel
KCU58_RS09775	COG1595	DNA-templated transcription, initiation
KCU58_RS09795	COG3038	cytochrome b561
KCU58_RS09825	COG2244	polysaccharide biosynthetic process
KCU58_RS09845	COG4106	trans-aconitate 2-methyltransferase activity
KCU58_RS09865	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS09870	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS09895	COG1132	(ABC) transporter
KCU58_RS09925	COG1530	ribonuclease E activity
KCU58_RS09940	COG0428	transporter
KCU58_RS09955	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KCU58_RS09955	COG0316	Belongs to the HesB IscA family
KCU58_RS09975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_RS09995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KCU58_RS10000	COG2957	Belongs to the agmatine deiminase family
KCU58_RS10010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KCU58_RS10015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KCU58_RS10020	COG0539	negative regulation of cytoplasmic translation
KCU58_RS10025	COG0776	regulation of translation
KCU58_RS10035	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KCU58_RS10040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCU58_RS10050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KCU58_RS10055	COG0183	Belongs to the thiolase family
KCU58_RS10060	COG1024	Enoyl-CoA hydratase
KCU58_RS10060	COG1250	3-hydroxyacyl-CoA dehydrogenase
KCU58_RS10075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KCU58_RS10085	COG1426	Protein conserved in bacteria
KCU58_RS10095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU58_RS10105	COG0746	molybdenum cofactor guanylyltransferase activity
KCU58_RS10115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KCU58_RS10120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KCU58_RS10120	COG0475	glutathione-regulated potassium exporter activity
KCU58_RS10140	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCU58_RS10150	COG0519	Catalyzes the synthesis of GMP from XMP
KCU58_RS10150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU58_RS10155	COG0582	viral genome integration into host DNA
KCU58_RS10265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU58_RS10270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KCU58_RS10280	COG0505	Belongs to the CarA family
KCU58_RS10290	COG2258	MOSC domain
KCU58_RS10295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KCU58_RS10315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU58_RS10325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCU58_RS10330	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KCU58_RS10365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCU58_RS10380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCU58_RS10390	COG1663	tetraacyldisaccharide 4'-kinase activity
KCU58_RS10395	COG1132	(ABC) transporter
KCU58_RS10405	COG0811	peptide transport
KCU58_RS10425	COG4591	ABC-type transport system involved in lipoprotein release permease component
KCU58_RS10435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KCU58_RS10440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KCU58_RS10450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KCU58_RS10455	COG2009	succinate dehydrogenase
KCU58_RS10475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCU58_RS10490	COG0129	dihydroxy-acid dehydratase activity
KCU58_RS10505	COG0395	ABC-type sugar transport system, permease component
KCU58_RS10540	COG2350	Protein conserved in bacteria
KCU58_RS10545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCU58_RS10550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCU58_RS10555	COG1187	pseudouridine synthase activity
KCU58_RS10580	COG0436	Aminotransferase
KCU58_RS10585	COG4133	protoheme IX ABC transporter activity
KCU58_RS10630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCU58_RS10635	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KCU58_RS10640	COG4988	ABC transporter
KCU58_RS10650	COG1294	oxidase, subunit
KCU58_RS10695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCU58_RS10700	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KCU58_RS10715	COG1024	Enoyl-CoA hydratase
KCU58_RS10725	COG1024	Enoyl-CoA hydratase
KCU58_RS10730	COG1024	Enoyl-CoA hydratase
KCU58_RS10770	COG0346	lactoylglutathione lyase activity
KCU58_RS10780	COG1304	FMN binding
KCU58_RS10785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCU58_RS10790	COG1649	PFAM Uncharacterised BCR, COG1649
KCU58_RS10940	COG1196	nuclear chromosome segregation
KCU58_RS11020	COG3728	DNA packaging
KCU58_RS11020	COG5484	DNA packaging
KCU58_RS11090	COG0270	DNA (cytosine-5-)-methyltransferase activity
KCU58_RS11105	COG0305	Participates in initiation and elongation during chromosome replication
KCU58_RS11255	COG0784	Response regulator, receiver
KCU58_RS11255	COG2205	protein histidine kinase activity
KCU58_RS11260	COG2183	response to ionizing radiation
KCU58_RS11265	COG0784	Response regulator, receiver
KCU58_RS11265	COG4191	Histidine kinase
KCU58_RS11275	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KCU58_RS11275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_RS11295	COG3243	poly(R)-hydroxyalkanoic acid synthase
KCU58_RS11305	COG1183	phosphatidylcholine synthase activity
KCU58_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS11325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KCU58_RS11335	COG0668	transmembrane transport
KCU58_RS11340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KCU58_RS11355	COG1914	H( )-stimulated, divalent metal cation uptake system
KCU58_RS11365	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
KCU58_RS11370	COG1501	Belongs to the glycosyl hydrolase 31 family
KCU58_RS11430	COG1487	ribonuclease activity
KCU58_RS11435	COG4691	Plasmid stability protein
KCU58_RS11465	COG1960	acyl-CoA dehydrogenase activity
KCU58_RS11470	COG2226	methyltransferase
KCU58_RS11475	COG0646	methionine synthase
KCU58_RS11475	COG1410	methionine synthase
KCU58_RS11480	COG0646	methionine synthase
KCU58_RS11480	COG1410	methionine synthase
KCU58_RS11500	COG2900	Belongs to the SlyX family
KCU58_RS11515	COG0386	Belongs to the glutathione peroxidase family
KCU58_RS11525	COG1725	Transcriptional regulator
KCU58_RS11530	COG1131	(ABC) transporter
KCU58_RS11575	COG2885	chlorophyll binding
KCU58_RS11580	COG2850	peptidyl-arginine hydroxylation
KCU58_RS11630	COG1132	(ABC) transporter
KCU58_RS11640	COG0287	Prephenate dehydrogenase
KCU58_RS11640	COG1605	Chorismate mutase
KCU58_RS11645	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KCU58_RS11650	COG0484	heat shock protein binding
KCU58_RS11655	COG0443	Heat shock 70 kDa protein
KCU58_RS11660	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCU58_RS11665	COG1420	regulation of RNA biosynthetic process
KCU58_RS11670	COG0497	DNA recombination
KCU58_RS11675	COG0735	belongs to the Fur family
KCU58_RS11680	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KCU58_RS11690	COG2867	negative regulation of translational initiation
KCU58_RS11695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCU58_RS11700	COG1404	Belongs to the peptidase S8 family
KCU58_RS11735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCU58_RS11750	COG0583	DNA-binding transcription factor activity
KCU58_RS11765	COG0415	Belongs to the DNA photolyase family
KCU58_RS11770	COG0305	Participates in initiation and elongation during chromosome replication
KCU58_RS11780	COG1960	acyl-CoA dehydrogenase activity
KCU58_RS11795	COG0084	hydrolase, TatD family'
KCU58_RS11800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KCU58_RS11850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCU58_RS11875	COG0386	Belongs to the glutathione peroxidase family
KCU58_RS11890	COG1846	Transcriptional regulator
KCU58_RS11935	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_RS11945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KCU58_RS11950	COG4290	ribonuclease
KCU58_RS11960	COG0488	(ABC) transporter
KCU58_RS11965	COG0513	Belongs to the DEAD box helicase family
KCU58_RS11990	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KCU58_RS11995	COG0657	acetylesterase activity
KCU58_RS12000	COG0625	glutathione transferase activity
KCU58_RS12010	COG0564	pseudouridine synthase activity
KCU58_RS12015	COG4681	YaeQ
KCU58_RS12020	COG2081	HI0933 family
KCU58_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS12060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCU58_RS12065	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCU58_RS12070	COG0802	atpase or kinase
KCU58_RS12075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCU58_RS12075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KCU58_RS12080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCU58_RS12125	COG1960	acyl-CoA dehydrogenase activity
KCU58_RS12135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCU58_RS12160	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS12170	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS12175	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS12225	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCU58_RS12230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCU58_RS12240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCU58_RS12275	COG1024	Enoyl-CoA hydratase
KCU58_RS12290	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCU58_RS12310	COG0277	FAD linked oxidase domain protein
KCU58_RS12315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KCU58_RS12330	COG0531	amino acid
KCU58_RS12335	COG0531	amino acid
KCU58_RS12340	COG0235	Class ii aldolase
KCU58_RS12345	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KCU58_RS12350	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KCU58_RS12370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCU58_RS12370	COG0140	phosphoribosyl-ATP diphosphatase activity
KCU58_RS12385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCU58_RS12400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCU58_RS12405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KCU58_RS12415	COG0124	histidyl-tRNA synthetase
KCU58_RS12420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCU58_RS12430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCU58_RS12440	COG2951	lytic endotransglycosylase activity
KCU58_RS12445	COG0083	homoserine kinase activity
KCU58_RS12450	COG0460	homoserine dehydrogenase
KCU58_RS12450	COG0527	aspartate kinase activity
KCU58_RS12465	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_RS12480	COG0167	dihydroorotate dehydrogenase activity
KCU58_RS12485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KCU58_RS12510	COG0671	phosphoesterase, PA-phosphatase related
KCU58_RS12525	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KCU58_RS12595	COG0166	Belongs to the GPI family
KCU58_RS12610	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KCU58_RS12620	COG0617	tRNA 3'-terminal CCA addition
KCU58_RS12640	COG0860	N-Acetylmuramoyl-L-alanine amidase
KCU58_RS12645	COG0477	Major facilitator Superfamily
KCU58_RS12650	COG2115	Belongs to the xylose isomerase family
KCU58_RS12655	COG1070	Carbohydrate kinase
KCU58_RS12675	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCU58_RS12695	COG0165	Argininosuccinate lyase
KCU58_RS12700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCU58_RS12710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KCU58_RS12715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KCU58_RS12720	COG0137	argininosuccinate synthase activity
KCU58_RS12725	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCU58_RS12740	COG2166	iron-sulfur cluster assembly
KCU58_RS12815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KCU58_RS12825	COG4677	pectinesterase activity
KCU58_RS12830	COG4677	pectinesterase activity
KCU58_RS12860	COG0402	S-adenosylhomocysteine deaminase activity
KCU58_RS12865	COG3548	integral membrane protein
KCU58_RS12875	COG1509	lysine 2,3-aminomutase activity
KCU58_RS12880	COG4251	negative regulation of phosphorylation
KCU58_RS12880	COG3706	GGDEF domain
KCU58_RS12880	COG2203	Gaf domain
KCU58_RS12880	COG5001	Diguanylate cyclase
KCU58_RS12905	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCU58_RS12910	COG1862	Preprotein translocase
KCU58_RS12920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCU58_RS12930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KCU58_RS12945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCU58_RS12950	COG3291	Pkd domain containing protein
KCU58_RS12955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCU58_RS12960	COG0405	Gamma-glutamyltransferase
KCU58_RS12965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KCU58_RS12980	COG0742	ribosomal rna small subunit methyltransferase
KCU58_RS13005	COG4771	TonB-dependent receptor
KCU58_RS13015	COG3507	Belongs to the glycosyl hydrolase 43 family
KCU58_RS13050	COG0531	amino acid
KCU58_RS13065	COG0006	proline dipeptidase activity
KCU58_RS13075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCU58_RS13090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_RS13095	COG3938	Belongs to the proline racemase family
KCU58_RS13105	COG0552	protein localization to endoplasmic reticulum
KCU58_RS13110	COG1194	a g-specific adenine glycosylase
KCU58_RS13160	COG0835	chemotaxis
KCU58_RS13175	COG0840	transmembrane signaling receptor activity
KCU58_RS13195	COG3300	MHYT domain
KCU58_RS13195	COG5001	Diguanylate cyclase
KCU58_RS13200	COG1185	polyribonucleotide nucleotidyltransferase activity
KCU58_RS13225	COG0195	Participates in both transcription termination and antitermination
KCU58_RS13240	COG1007	ATP synthesis coupled electron transport
KCU58_RS13275	COG1034	ATP synthesis coupled electron transport
KCU58_RS13280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KCU58_RS13285	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KCU58_RS13290	COG0649	NAD binding
KCU58_RS13295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCU58_RS13305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KCU58_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS13345	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCU58_RS13390	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCU58_RS13405	COG2890	protein-(glutamine-N5) methyltransferase activity
KCU58_RS13415	COG0688	phosphatidylethanolamine metabolic process
KCU58_RS13420	COG0741	lytic transglycosylase activity
KCU58_RS13425	COG0433	COG0433 Predicted ATPase
KCU58_RS13430	COG0494	nUDIX hydrolase
KCU58_RS13445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KCU58_RS13465	COG1714	RDD family
KCU58_RS13470	COG0717	Belongs to the dCTP deaminase family
KCU58_RS13475	COG0489	protein tyrosine kinase activity
KCU58_RS13485	COG4771	TonB-dependent receptor
KCU58_RS13490	COG4771	TonB-dependent receptor
KCU58_RS13495	COG0457	Tetratricopeptide repeat
KCU58_RS13510	COG3590	peptidase
KCU58_RS13560	COG0697	spore germination
KCU58_RS13580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_RS13585	COG2311	Membrane
KCU58_RS13590	COG1047	Peptidyl-prolyl cis-trans
KCU58_RS13595	COG0791	NLP P60 protein
KCU58_RS13600	COG0791	NLP P60 protein
KCU58_RS13615	COG1607	acyl-coa hydrolase
KCU58_RS13625	COG1301	dicarboxylic acid transport
KCU58_RS13630	COG1785	Belongs to the alkaline phosphatase family
KCU58_RS13640	COG0037	tRNA processing
KCU58_RS13645	COG1722	exodeoxyribonuclease VII activity
KCU58_RS13650	COG0142	geranyltranstransferase activity
KCU58_RS13660	COG1858	cytochrome C peroxidase
KCU58_RS13685	COG0515	serine threonine protein kinase
KCU58_RS13685	COG2815	serine threonine protein kinase
KCU58_RS13690	COG0631	protein serine/threonine phosphatase activity
KCU58_RS13780	COG0312	modulator of DNA gyrase
KCU58_RS13790	COG0312	modulator of DNA gyrase
KCU58_RS13810	COG2968	Membrane
KCU58_RS13825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCU58_RS13840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCU58_RS13855	COG0495	leucyl-tRNA aminoacylation
KCU58_RS13865	COG3118	belongs to the thioredoxin family
KCU58_RS13880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCU58_RS13890	COG2040	homocysteine
KCU58_RS13895	COG0833	amino acid
KCU58_RS13905	COG0346	lactoylglutathione lyase activity
KCU58_RS13925	COG2878	Part of a membrane complex involved in electron transport
KCU58_RS13940	COG1595	DNA-templated transcription, initiation
KCU58_RS13965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KCU58_RS13985	COG0251	oxidation-reduction process
KCU58_RS13995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCU58_RS13995	COG0392	lysyltransferase activity
KCU58_RS14025	COG2814	Major facilitator Superfamily
KCU58_RS14035	COG1902	pentaerythritol trinitrate reductase activity
KCU58_RS14040	COG2824	Alkylphosphonate utilization operon protein PhnA
KCU58_RS14045	COG1047	Peptidyl-prolyl cis-trans
KCU58_RS14050	COG1077	Cell shape determining protein MreB Mrl
KCU58_RS14085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KCU58_RS14095	COG1451	nucleotide metabolic process
KCU58_RS14120	COG2198	Histidine kinase
KCU58_RS14120	COG2205	protein histidine kinase activity
KCU58_RS14120	COG0784	Response regulator, receiver
KCU58_RS14130	COG2186	Transcriptional regulator
KCU58_RS14135	COG3250	beta-galactosidase activity
KCU58_RS14200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCU58_RS14200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCU58_RS14200	COG1703	isobutyryl-CoA mutase activity
KCU58_RS14235	COG0183	Belongs to the thiolase family
KCU58_RS14245	COG0443	Heat shock 70 kDa protein
KCU58_RS14275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCU58_RS14275	COG1793	dna ligase
KCU58_RS14280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KCU58_RS14280	COG1793	dna ligase
KCU58_RS14285	COG1201	RNA secondary structure unwinding
KCU58_RS14295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU58_RS14300	COG1278	Cold shock
KCU58_RS14305	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCU58_RS14310	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KCU58_RS14315	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_RS14325	COG2954	triphosphatase activity
KCU58_RS14335	COG0745	RESPONSE REGULATOR receiver
KCU58_RS14340	COG1381	Involved in DNA repair and RecF pathway recombination
KCU58_RS14345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCU58_RS14360	COG0681	Belongs to the peptidase S26 family
KCU58_RS14365	COG0481	GTPase activity
KCU58_RS14370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCU58_RS14400	COG2855	membrane
KCU58_RS14415	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCU58_RS14435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KCU58_RS14445	COG0534	Mate efflux family protein
KCU58_RS14450	COG0335	large ribosomal subunit rRNA binding
KCU58_RS14455	COG0336	Belongs to the RNA methyltransferase TrmD family
KCU58_RS14460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCU58_RS14475	COG2070	2-Nitropropane dioxygenase
KCU58_RS14480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCU58_RS14505	COG0475	glutathione-regulated potassium exporter activity
KCU58_RS14515	COG0625	glutathione transferase activity
KCU58_RS14520	COG1082	Xylose isomerase domain protein TIM barrel
KCU58_RS14530	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCU58_RS14535	COG1172	Belongs to the binding-protein-dependent transport system permease family
KCU58_RS14540	COG1129	ABC transporter
KCU58_RS14545	COG1879	ABC-type sugar transport system periplasmic component
KCU58_RS14550	COG1012	belongs to the aldehyde dehydrogenase family
KCU58_RS14570	COG0129	dihydroxy-acid dehydratase activity
KCU58_RS14595	COG2207	Transcriptional regulator
KCU58_RS14615	COG1317	bacterial-type flagellum organization
KCU58_RS14640	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCU58_RS14665	COG4794	Type iii secretion
KCU58_RS14695	COG0745	RESPONSE REGULATOR receiver
KCU58_RS14725	COG3152	Membrane
KCU58_RS14735	COG0156	8-amino-7-oxononanoate synthase activity
KCU58_RS14745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KCU58_RS14750	COG1845	cytochrome c oxidase, subunit III
KCU58_RS14755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCU58_RS14775	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCU58_RS14790	COG0196	riboflavin kinase activity
KCU58_RS14805	COG0728	peptidoglycan biosynthetic process
KCU58_RS14820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KCU58_RS14825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KCU58_RS14830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCU58_RS14835	COG0824	Thioesterase
KCU58_RS14845	COG1024	Enoyl-CoA hydratase
KCU58_RS14850	COG1946	Acyl-CoA thioesterase
KCU58_RS14860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCU58_RS14865	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KCU58_RS14880	COG4638	Rieske (2fe-2S)
KCU58_RS14925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCU58_RS14970	COG1643	Atp-dependent helicase
KCU58_RS14975	COG0783	Belongs to the Dps family
KCU58_RS14980	COG0514	ATP-dependent DNA helicase (RecQ)
KCU58_RS15000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCU58_RS15005	COG0602	queuosine metabolic process
KCU58_RS15015	COG2885	chlorophyll binding
KCU58_RS15030	COG0848	biopolymer transport protein
KCU58_RS15040	COG0824	Thioesterase
KCU58_RS15045	COG2255	four-way junction helicase activity
KCU58_RS15050	COG3158	transport of potassium into the cell
KCU58_RS15055	COG0632	four-way junction helicase activity
KCU58_RS15065	COG0217	transcriptional regulatory protein
KCU58_RS15105	COG3142	Participates in the control of copper homeostasis
KCU58_RS15110	COG1446	asparaginase
KCU58_RS15130	COG2201	protein-glutamate methylesterase activity
KCU58_RS15135	COG2198	Histidine kinase
KCU58_RS15135	COG0784	Response regulator, receiver
KCU58_RS15135	COG0643	Histidine kinase
KCU58_RS15140	COG0840	transmembrane signaling receptor activity
KCU58_RS15145	COG0835	chemotaxis
KCU58_RS15160	COG0189	ligase activity
KCU58_RS15180	COG1199	ATP-dependent helicase activity
KCU58_RS15190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KCU58_RS15195	COG1216	Glycosyl transferase, family 2
KCU58_RS15200	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCU58_RS15220	COG4585	Histidine kinase
KCU58_RS15230	COG0850	regulation of cytokinetic process
KCU58_RS15235	COG2894	cell division
KCU58_RS15240	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KCU58_RS15250	COG2205	protein histidine kinase activity
KCU58_RS15255	COG0745	RESPONSE REGULATOR receiver
KCU58_RS15265	COG2194	sulfuric ester hydrolase activity
KCU58_RS15285	COG2814	Major facilitator Superfamily
KCU58_RS15310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCU58_RS15310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCU58_RS15320	COG0753	catalase activity
KCU58_RS15330	COG4106	trans-aconitate 2-methyltransferase activity
KCU58_RS15345	COG1063	alcohol dehydrogenase
KCU58_RS15355	COG3459	Glycosyltransferase 36 associated
KCU58_RS15410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCU58_RS15420	COG0330	HflC and HflK could
KCU58_RS15425	COG0330	HflC and HflK could
KCU58_RS15430	COG0604	alcohol dehydrogenase
KCU58_RS15450	COG0678	peroxiredoxin activity
KCU58_RS15460	COG4953	penicillin-binding protein 1C
KCU58_RS15480	COG2373	Large extracellular alpha-helical protein
KCU58_RS15505	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCU58_RS15520	COG0372	Belongs to the citrate synthase family
KCU58_RS15525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCU58_RS15540	COG0587	DNA-directed DNA polymerase activity
KCU58_RS15575	COG2161	toxin-antitoxin pair type II binding
KCU58_RS15580	COG4115	mRNA cleavage
KCU58_RS15600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCU58_RS15605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCU58_RS15610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCU58_RS15620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU58_RS15625	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS15630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KCU58_RS15635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_RS15645	COG1399	metal-binding, possibly nucleic acid-binding protein
KCU58_RS15670	COG0714	Associated with various cellular activities
KCU58_RS15690	COG0537	adenosine 5'-monophosphoramidase activity
KCU58_RS15730	COG0314	molybdopterin synthase activity
KCU58_RS15735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KCU58_RS15740	COG0315	cyclic pyranopterin monophosphate synthase activity
KCU58_RS15750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCU58_RS15755	COG1234	tRNA 3'-trailer cleavage
KCU58_RS15765	COG0859	PFAM glycosyl transferase family 9
KCU58_RS15790	COG0631	protein serine/threonine phosphatase activity
KCU58_RS15810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KCU58_RS15815	COG1388	LysM domain
KCU58_RS15815	COG3942	CHAP domain
KCU58_RS15850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCU58_RS15860	COG0544	peptidyl-prolyl cis-trans isomerase activity
KCU58_RS15900	COG0473	3-isopropylmalate dehydrogenase activity
KCU58_RS15915	COG4783	chaperone-mediated protein folding
KCU58_RS15930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KCU58_RS15935	COG0248	Ppx GppA phosphatase
KCU58_RS15940	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS15950	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KCU58_RS15965	COG2833	Protein of unknown function (DUF455)
KCU58_RS15985	COG0285	dihydrofolate synthase activity
KCU58_RS15990	COG0588	phosphoglycerate mutase activity
KCU58_RS16010	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KCU58_RS16015	COG4208	sulfate ABC transporter
KCU58_RS16020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KCU58_RS16025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KCU58_RS16030	COG0156	8-amino-7-oxononanoate synthase activity
KCU58_RS16045	COG2885	chlorophyll binding
KCU58_RS16065	COG0667	Aldo Keto reductase
KCU58_RS16075	COG0446	pyridine nucleotide-disulphide oxidoreductase
KCU58_RS16075	COG1902	pentaerythritol trinitrate reductase activity
KCU58_RS16120	COG0625	glutathione transferase activity
KCU58_RS16145	COG0039	L-malate dehydrogenase activity
KCU58_RS16155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCU58_RS16160	COG1217	gtp-binding protein TYPA
KCU58_RS16175	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KCU58_RS16185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KCU58_RS16190	COG0203	ribosomal protein L17
KCU58_RS16215	COG0201	protein transport
KCU58_RS16225	COG1841	ribosomal large subunit assembly
KCU58_RS16255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCU58_RS16260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCU58_RS16270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCU58_RS16275	COG0255	Belongs to the universal ribosomal protein uL29 family
KCU58_RS16300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCU58_RS16305	COG0089	rRNA binding
KCU58_RS16310	COG0088	Forms part of the polypeptide exit tunnel
KCU58_RS16320	COG0051	transcription antitermination factor activity, RNA binding
KCU58_RS16325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCU58_RS16330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCU58_RS16345	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCU58_RS16355	COG0222	ribosome binding
KCU58_RS16370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCU58_RS16375	COG0250	Participates in transcription elongation, termination and antitermination
KCU58_RS16380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KCU58_RS16390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCU58_RS16410	COG0012	GTP binding
KCU58_RS16415	COG0193	aminoacyl-tRNA hydrolase activity
KCU58_RS16425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCU58_RS16435	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCU58_RS16450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KCU58_RS16455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCU58_RS16500	COG0488	(ABC) transporter
KCU58_RS16540	COG3634	alkyl hydroperoxide reductase activity
KCU58_RS16545	COG0583	DNA-binding transcription factor activity
KCU58_RS16560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCU58_RS16590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCU58_RS16595	COG0697	spore germination
KCU58_RS16635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU58_RS16640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCU58_RS16650	COG2096	Adenosyltransferase
KCU58_RS16660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KCU58_RS16665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KCU58_RS16670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KCU58_RS16675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCU58_RS16680	COG2967	ApaG domain
KCU58_RS16685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KCU58_RS16745	COG2188	Transcriptional regulator
KCU58_RS16755	COG1450	Type ii and iii secretion system protein
KCU58_RS16770	COG3166	PFAM Fimbrial assembly family protein
KCU58_RS16775	COG3156	type II secretion system protein K
KCU58_RS16780	COG4795	General secretion pathway protein
KCU58_RS16785	COG2165	general secretion pathway protein
KCU58_RS16790	COG4970	Tfp pilus assembly protein FimT
KCU58_RS16795	COG2165	general secretion pathway protein
KCU58_RS16800	COG1459	type II secretion system
KCU58_RS16805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCU58_RS16810	COG1404	Belongs to the peptidase S8 family
KCU58_RS16815	COG5295	Hep Hag repeat protein
KCU58_RS16825	COG0840	transmembrane signaling receptor activity
KCU58_RS16830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCU58_RS16830	COG0047	phosphoribosylformylglycinamidine synthase activity
KCU58_RS16835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KCU58_RS16840	COG4974	Belongs to the 'phage' integrase family
KCU58_RS16865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCU58_RS16870	COG2927	DNA polymerase III (CHI subunit)
KCU58_RS16905	COG1183	phosphatidylcholine synthase activity
KCU58_RS16915	COG0442	prolyl-tRNA aminoacylation
KCU58_RS16930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KCU58_RS16935	COG1127	ABC transporter
KCU58_RS16940	COG3218	ABC-type transport auxiliary lipoprotein component
KCU58_RS16940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KCU58_RS16970	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KCU58_RS16975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCU58_RS16980	COG0662	Cupin 2, conserved barrel domain protein
KCU58_RS16980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KCU58_RS17005	COG2086	electron transfer activity
KCU58_RS17020	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KCU58_RS17020	COG0546	phosphoglycolate phosphatase activity
KCU58_RS17025	COG0277	FAD linked oxidase domain protein
KCU58_RS17030	COG0300	oxidoreductase activity
KCU58_RS17050	COG0493	'glutamate synthase
KCU58_RS17090	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS17090	COG1216	Glycosyl transferase, family 2
KCU58_RS17095	COG0438	transferase activity, transferring glycosyl groups
KCU58_RS17095	COG1216	Glycosyl transferase, family 2
KCU58_RS17100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KCU58_RS17115	COG0626	cystathionine gamma-synthase activity
KCU58_RS17145	COG0625	glutathione transferase activity
KCU58_RS17160	COG0720	synthase
KCU58_RS17170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KCU58_RS17175	COG1956	GAF domain-containing protein
KCU58_RS17185	COG4206	TonB-dependent receptor
KCU58_RS17190	COG0546	phosphoglycolate phosphatase activity
KCU58_RS17195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCU58_RS17215	COG0339	signal peptide processing
KCU58_RS17230	COG2217	Heavy metal translocating P-type atpase
KCU58_RS17245	COG2132	Multicopper oxidase
KCU58_RS17260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KCU58_RS17270	COG1136	(ABC) transporter
KCU58_RS17275	COG0577	efflux transmembrane transporter activity
KCU58_RS17275	COG1136	(ABC) transporter
KCU58_RS17280	COG0577	efflux transmembrane transporter activity
KCU58_RS17280	COG1136	(ABC) transporter
KCU58_RS17285	COG0577	efflux transmembrane transporter activity
KCU58_RS17285	COG1136	(ABC) transporter
KCU58_RS17305	COG4191	Histidine kinase
KCU58_RS17315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCU58_RS17330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KCU58_RS17345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCU58_RS17355	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCU58_RS17365	COG0356	it plays a direct role in the translocation of protons across the membrane
KCU58_RS17380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCU58_RS17385	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU58_RS17420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCU58_RS17425	COG0697	spore germination
KCU58_RS17430	COG1666	GTP binding
KCU58_RS17440	COG1187	pseudouridine synthase activity
KCU58_RS17465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KCU58_RS17465	COG2205	protein histidine kinase activity
KCU58_RS17490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KCU58_RS17565	COG0842	Transport permease protein
KCU58_RS17570	COG1131	(ABC) transporter
KCU58_RS17575	COG0025	NhaP-type Na H and K H
KCU58_RS17585	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KCU58_RS17590	COG1573	uracil-dna glycosylase
KCU58_RS17600	COG3384	dioxygenase
KCU58_RS17620	COG0667	Aldo Keto reductase
KCU58_RS17625	COG0667	Aldo Keto reductase
KCU58_RS17635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCU58_RS17640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU58_RS17665	COG3706	GGDEF domain
KCU58_RS17670	COG2146	nitrite reductase [NAD(P)H] activity
KCU58_RS17675	COG5001	Diguanylate cyclase
KCU58_RS17705	COG4106	trans-aconitate 2-methyltransferase activity
KCU58_RS17715	COG2076	Multidrug Resistance protein
KCU58_RS17725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KCU58_RS17745	COG3279	Response regulator of the LytR AlgR family
KCU58_RS17750	COG3275	phosphorelay sensor kinase activity
KCU58_RS17775	COG0531	amino acid
KCU58_RS17785	COG5297	Belongs to the glycosyl hydrolase family 6
KCU58_RS17785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
KCU58_RS17800	COG0741	lytic transglycosylase activity
KCU58_RS17815	COG2207	Transcriptional regulator
KCU58_RS17825	COG0598	Magnesium transport protein CorA
KCU58_RS17830	COG1113	amino acid transport
KCU58_RS17835	COG0697	spore germination
KCU58_RS17865	COG5520	Belongs to the glycosyl hydrolase 30 family
KCU58_RS17975	COG0840	transmembrane signaling receptor activity
KCU58_RS17990	COG2353	YceI-like domain
KCU58_RS18020	COG0584	glycerophosphoryl diester phosphodiesterase
KCU58_RS18035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KCU58_RS18055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCU58_RS18075	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KCU58_RS18085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KCU58_RS18090	COG0459	protein refolding
KCU58_RS18105	COG1324	tolerance protein
KCU58_RS18115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KCU58_RS18125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KCU58_RS18130	COG0511	ligase activity, forming carbon-carbon bonds
KCU58_RS18135	COG0439	Biotin carboxylase
KCU58_RS18150	COG2264	protein methyltransferase activity
KCU58_RS18170	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KCU58_RS18175	COG4589	Belongs to the CDS family
KCU58_RS18200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCU58_RS18205	COG0138	bifunctional purine biosynthesis protein purh
KCU58_RS18210	COG0151	Belongs to the GarS family
KCU58_RS18215	COG1289	transmembrane transporter activity
KCU58_RS18220	COG2814	Major facilitator Superfamily
KCU58_RS18260	COG2816	NAD+ diphosphatase activity
KCU58_RS18300	COG2906	2 iron, 2 sulfur cluster binding
KCU58_RS18330	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KCU58_RS18345	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KCU58_RS18350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KCU58_RS18355	COG0730	response to heat
KCU58_RS18370	COG0134	indole-3-glycerol-phosphate synthase activity
KCU58_RS18375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCU58_RS18395	COG1597	lipid kinase activity
KCU58_RS18410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KCU58_RS18425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KCU58_RS18430	COG2111	Na H antiporter
KCU58_RS18430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KCU58_RS18435	COG1006	Multisubunit Na H antiporter MnhC subunit
KCU58_RS18440	COG0651	ATP synthesis coupled electron transport
KCU58_RS18445	COG1863	multisubunit Na H antiporter MnhE subunit
KCU58_RS18450	COG2212	antiporter activity
KCU58_RS18455	COG1320	monovalent cation:proton antiporter activity
KCU58_RS18460	COG0530	calcium, potassium:sodium antiporter activity
KCU58_RS18475	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KCU58_RS18495	COG3104	oligopeptide transport
KCU58_RS18530	COG0508	dehydrogenase complex catalyzes the overall conversion of
KCU58_RS18560	COG0513	Belongs to the DEAD box helicase family
KCU58_RS18575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCU58_RS18585	COG2354	Protein conserved in bacteria
KCU58_RS18610	COG3264	Mechanosensitive ion channel
KCU58_RS18610	COG1196	nuclear chromosome segregation
KCU58_RS18615	COG3321	synthase
KCU58_RS18615	COG0604	alcohol dehydrogenase
KCU58_RS18615	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS18635	COG1595	DNA-templated transcription, initiation
KCU58_RS18650	COG1802	Transcriptional regulator
KCU58_RS18685	COG3052	prosthetic group binding
KCU58_RS18695	COG1414	Transcriptional regulator
KCU58_RS18700	COG0738	Major facilitator superfamily
KCU58_RS18705	COG3254	rhamnose metabolic process
KCU58_RS18710	COG4948	Mandelate Racemase Muconate Lactonizing
KCU58_RS18715	COG0179	Fumarylacetoacetate (FAA) hydrolase
KCU58_RS18720	COG1028	Short-chain dehydrogenase reductase Sdr
KCU58_RS18755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KCU58_RS18770	COG4807	Protein conserved in bacteria
KCU58_RS18810	COG0823	Involved in the tonB-independent uptake of proteins
KCU58_RS18810	COG1506	peptidase
KCU58_RS18875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCU58_RS18895	COG0628	permease
KCU58_RS18900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KCU58_RS18905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCU58_RS18910	COG0753	catalase activity
KCU58_RS18935	COG1136	(ABC) transporter
KCU58_RS18940	COG0577	efflux transmembrane transporter activity
KCU58_RS18960	COG0697	spore germination
KCU58_RS18975	COG0180	Tryptophanyl-tRNA synthetase
KCU58_RS19010	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCU58_RS19015	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KCU58_RS19015	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KCU58_RS19025	COG3228	Belongs to the MtfA family
KCU58_RS19055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCU58_RS19080	COG2084	Dehydrogenase
KCU58_RS19085	COG1902	pentaerythritol trinitrate reductase activity
KCU58_RS19110	COG1404	Belongs to the peptidase S8 family
KCU58_RS19115	COG2814	Major facilitator Superfamily
KCU58_RS19120	COG0583	DNA-binding transcription factor activity
KCU58_RS19140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCU58_RS19145	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCU58_RS19155	COG1764	response to oxidative stress
KCU58_RS19160	COG1846	Transcriptional regulator
KCU58_RS19165	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KCU58_RS19175	COG0697	spore germination
KCU58_RS19180	COG0523	cobalamin synthesis protein
KCU58_RS19190	COG1742	UPF0060 membrane protein
KCU58_RS19210	COG1960	acyl-CoA dehydrogenase activity
KCU58_RS19215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KCU58_RS19245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCU58_RS19250	COG3387	PFAM Glycoside hydrolase 15-related
KCU58_RS19255	COG0745	RESPONSE REGULATOR receiver
KCU58_RS19280	COG1404	Belongs to the peptidase S8 family
KCU58_RS19290	COG3100	YcgL domain-containing protein
KCU58_RS19295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KCU58_RS19305	COG0463	Glycosyl transferase, family 2
KCU58_RS19340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KCU58_RS19355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCU58_RS19380	COG1294	oxidase, subunit
KCU58_RS19385	COG1271	oxidase subunit
KCU58_RS19405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCU58_RS19410	COG0408	coproporphyrinogen oxidase activity
KCU58_RS19420	COG2323	membrane
KCU58_RS19425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_RS19425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCU58_RS19445	COG0589	response to stress
KCU58_RS19465	COG0210	DNA helicase
KCU58_RS19515	COG0463	Glycosyl transferase, family 2
KCU58_RS19525	COG1475	DNA binding
KCU58_RS19530	COG1192	Involved in chromosome partitioning
KCU58_RS19535	COG0357	Ribosomal RNA small subunit methyltransferase G
KCU58_RS19550	COG2091	lysine biosynthetic process via aminoadipic acid
KCU58_RS19575	COG0477	Major facilitator Superfamily
KCU58_RS19595	COG1971	Probably functions as a manganese efflux pump
KCU58_RS19600	COG2205	protein histidine kinase activity
KCU58_RS19605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCU58_RS19610	COG3459	Glycosyltransferase 36 associated
KCU58_RS19615	COG2211	Major facilitator Superfamily
KCU58_RS19620	COG3265	gluconokinase activity
KCU58_RS19635	COG2911	Protein conserved in bacteria
KCU58_RS19640	COG0729	surface antigen
KCU58_RS19660	COG3132	Protein of unknown function, DUF480
KCU58_RS19705	COG0284	orotidine-5'-phosphate decarboxylase activity
KCU58_RS19730	COG2937	Belongs to the GPAT DAPAT family
KCU58_RS19755	COG2211	Major facilitator Superfamily
KCU58_RS19770	COG3693	PFAM glycoside hydrolase, family 10
KCU58_RS19790	COG3386	PFAM SMP-30 Gluconolaconase
KCU58_RS19805	COG0246	Mannitol dehydrogenase
KCU58_RS19810	COG1472	Belongs to the glycosyl hydrolase 3 family
KCU58_RS19820	COG4948	Mandelate Racemase Muconate Lactonizing
KCU58_RS19830	COG3661	Belongs to the glycosyl hydrolase 67 family
KCU58_RS19840	COG2115	Belongs to the xylose isomerase family
KCU58_RS19845	COG0037	tRNA processing
KCU58_RS19865	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KCU58_RS19875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCU58_RS19885	COG0805	protein transport
KCU58_RS19895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KCU58_RS19895	COG0519	Catalyzes the synthesis of GMP from XMP
KCU58_RS19900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCU58_RS19920	COG0210	DNA helicase
KCU58_RS19925	COG1435	thymidine kinase activity
KCU58_RS19935	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KCU58_RS19960	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KCU58_RS19975	COG1119	ATPase activity
KCU58_RS19995	COG0706	membrane insertase activity
KCU58_RS20000	COG0594	ribonuclease P activity
KCU58_RS20065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCU58_RS20165	COG3451	type IV secretory pathway VirB4
KCU58_RS20170	COG5268	conjugation
KCU58_RS20180	COG4962	Type ii secretion system protein e
KCU58_RS20185	COG4962	Type ii secretion system protein e
KCU58_RS20190	COG4962	Type ii secretion system protein e