locus-tag	class	description
NZ30_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NZ30_RS00020	COG0187	DNA topoisomerase II activity
NZ30_RS00025	COG1266	CAAX protease self-immunity
NZ30_RS00030	COG0501	Belongs to the peptidase M48B family
NZ30_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NZ30_RS00090	COG1280	lysine exporter protein (LysE YggA)
NZ30_RS00105	COG4772	TonB-dependent receptor
NZ30_RS00115	COG3284	Transcriptional regulator
NZ30_RS00120	COG1012	belongs to the aldehyde dehydrogenase family
NZ30_RS00155	COG1304	FMN binding
NZ30_RS00160	COG2186	Transcriptional regulator
NZ30_RS00185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZ30_RS00255	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NZ30_RS00275	COG4771	TonB-dependent receptor
NZ30_RS00325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NZ30_RS00340	COG3507	Belongs to the glycosyl hydrolase 43 family
NZ30_RS00345	COG1609	Transcriptional regulator
NZ30_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS00370	COG3186	Phenylalanine-4-hydroxylase
NZ30_RS00375	COG1522	sequence-specific DNA binding
NZ30_RS00395	COG1752	Esterase of the alpha-beta hydrolase superfamily
NZ30_RS00420	COG0671	phosphoesterase, PA-phosphatase related
NZ30_RS00435	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NZ30_RS00465	COG1929	Belongs to the glycerate kinase type-1 family
NZ30_RS00475	COG0531	amino acid
NZ30_RS00480	COG4566	intracellular signal transduction
NZ30_RS00485	COG4191	Histidine kinase
NZ30_RS00505	COG1322	Protein conserved in bacteria
NZ30_RS00510	COG0386	Belongs to the glutathione peroxidase family
NZ30_RS00515	COG2853	Lipoprotein
NZ30_RS00530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NZ30_RS00535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NZ30_RS00540	COG1127	ABC transporter
NZ30_RS00545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NZ30_RS00550	COG1074	ATP-dependent DNA helicase activity
NZ30_RS00555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NZ30_RS00575	COG0537	adenosine 5'-monophosphoramidase activity
NZ30_RS00640	COG0477	Major facilitator Superfamily
NZ30_RS00645	COG0302	gtp cyclohydrolase
NZ30_RS00685	COG2951	lytic endotransglycosylase activity
NZ30_RS00745	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NZ30_RS00750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NZ30_RS00755	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NZ30_RS00760	COG0493	'glutamate synthase
NZ30_RS00765	COG0067	glutamate synthase
NZ30_RS00765	COG0069	glutamate synthase activity
NZ30_RS00765	COG0070	glutamate synthase
NZ30_RS00840	COG1205	dead DEAH box helicase
NZ30_RS00840	COG1111	helicase
NZ30_RS00870	COG2271	Major facilitator Superfamily
NZ30_RS00920	COG1192	Involved in chromosome partitioning
NZ30_RS00925	COG2062	phosphohistidine phosphatase, SixA
NZ30_RS00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NZ30_RS00940	COG2050	protein possibly involved in aromatic compounds catabolism
NZ30_RS00950	COG2267	carboxylic ester hydrolase activity
NZ30_RS00965	COG1881	PFAM PEBP family protein
NZ30_RS00970	COG1968	undecaprenyl-diphosphatase activity
NZ30_RS00975	COG0174	glutamine synthetase
NZ30_RS00980	COG0347	Belongs to the P(II) protein family
NZ30_RS00985	COG0004	ammonium transporteR
NZ30_RS00990	COG3852	Histidine kinase
NZ30_RS00995	COG2204	response regulator
NZ30_RS01000	COG2032	superoxide dismutase activity
NZ30_RS01005	COG2032	superoxide dismutase activity
NZ30_RS01020	COG0183	Belongs to the thiolase family
NZ30_RS01060	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NZ30_RS01065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NZ30_RS01075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NZ30_RS01085	COG0612	Peptidase, M16
NZ30_RS01095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZ30_RS01105	COG0596	Alpha beta hydrolase
NZ30_RS01115	COG0727	PFAM Uncharacterised protein family (UPF0153)
NZ30_RS01120	COG0318	PFAM AMP-dependent synthetase and ligase
NZ30_RS01135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NZ30_RS01145	COG1181	Belongs to the D-alanine--D-alanine ligase family
NZ30_RS01160	COG4232	protein-disulfide reductase activity
NZ30_RS01165	COG0564	pseudouridine synthase activity
NZ30_RS01185	COG0339	signal peptide processing
NZ30_RS01210	COG0583	DNA-binding transcription factor activity
NZ30_RS01215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NZ30_RS01220	COG2224	Isocitrate lyase
NZ30_RS01255	COG0659	secondary active sulfate transmembrane transporter activity
NZ30_RS01290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NZ30_RS01295	COG2130	NADP-dependent
NZ30_RS01310	COG1187	pseudouridine synthase activity
NZ30_RS01330	COG0084	hydrolase, TatD family'
NZ30_RS01420	COG0842	Transport permease protein
NZ30_RS01425	COG1131	(ABC) transporter
NZ30_RS01430	COG0543	2 iron, 2 sulfur cluster binding
NZ30_RS01430	COG0633	Ferredoxin
NZ30_RS01440	COG1476	TRANSCRIPTIONal
NZ30_RS01450	COG4555	ABC transporter
NZ30_RS01470	COG0625	glutathione transferase activity
NZ30_RS01550	COG1199	ATP-dependent helicase activity
NZ30_RS01605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NZ30_RS01625	COG0628	permease
NZ30_RS01640	COG0129	dihydroxy-acid dehydratase activity
NZ30_RS01645	COG2133	pyrroloquinoline quinone binding
NZ30_RS01695	COG0754	glutathionylspermidine amidase activity
NZ30_RS01705	COG0714	Associated with various cellular activities
NZ30_RS01755	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NZ30_RS01770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NZ30_RS01775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NZ30_RS01800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NZ30_RS01820	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS01840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NZ30_RS01850	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NZ30_RS01880	COG0606	chelatase, subunit chli
NZ30_RS01885	COG2960	long-chain fatty acid transporting porin activity
NZ30_RS01905	COG1166	arginine decarboxylase activity
NZ30_RS01920	COG2755	lipolytic protein G-D-S-L family
NZ30_RS01920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NZ30_RS01925	COG0583	DNA-binding transcription factor activity
NZ30_RS01945	COG4221	oxidoreductase activity
NZ30_RS01965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NZ30_RS01985	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NZ30_RS01995	COG2814	Major facilitator Superfamily
NZ30_RS02010	COG0739	heme binding
NZ30_RS02015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NZ30_RS02045	COG1064	alcohol dehydrogenase
NZ30_RS02050	COG2234	aminopeptidase activity
NZ30_RS02060	COG4942	peptidase
NZ30_RS02065	COG0793	Belongs to the peptidase S41A family
NZ30_RS02095	COG0531	amino acid
NZ30_RS02115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NZ30_RS02115	COG1565	acr, cog1565
NZ30_RS02120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NZ30_RS02125	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NZ30_RS02155	COG0109	protoheme IX farnesyltransferase activity
NZ30_RS02170	COG0358	DNA primase activity
NZ30_RS02175	COG1295	ribonuclease BN
NZ30_RS02195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NZ30_RS02200	COG2308	Evidence 4 Homologs of previously reported genes of
NZ30_RS02235	COG0531	amino acid
NZ30_RS02250	COG4948	Mandelate Racemase Muconate Lactonizing
NZ30_RS02260	COG4771	TonB-dependent receptor
NZ30_RS02265	COG3023	N-Acetylmuramoyl-L-alanine amidase
NZ30_RS02290	COG3501	Rhs element vgr protein
NZ30_RS02290	COG3409	Peptidoglycan-binding domain 1 protein
NZ30_RS02330	COG5383	Protein conserved in bacteria
NZ30_RS02345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NZ30_RS02350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NZ30_RS02365	COG1652	LysM domain
NZ30_RS02375	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NZ30_RS02380	COG1518	maintenance of DNA repeat elements
NZ30_RS02430	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NZ30_RS02440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NZ30_RS02445	COG3118	belongs to the thioredoxin family
NZ30_RS02455	COG2884	Cell division ATP-binding protein ftsE
NZ30_RS02460	COG2177	Part of the ABC transporter FtsEX involved in
NZ30_RS02465	COG3437	response regulator, receiver
NZ30_RS02470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NZ30_RS02475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NZ30_RS02480	COG2860	membrane
NZ30_RS02485	COG1252	NADH dehydrogenase
NZ30_RS02490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NZ30_RS02500	COG0534	Mate efflux family protein
NZ30_RS02505	COG0616	signal peptide processing
NZ30_RS02515	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS02535	COG0009	L-threonylcarbamoyladenylate synthase
NZ30_RS02540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NZ30_RS02540	COG1754	DNA topoisomerase type I activity
NZ30_RS02545	COG1714	RDD family
NZ30_RS02560	COG0758	DNA mediated transformation
NZ30_RS02565	COG1652	LysM domain
NZ30_RS02570	COG0242	peptide deformylase activity
NZ30_RS02575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NZ30_RS02580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NZ30_RS02580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NZ30_RS02585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NZ30_RS02620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NZ30_RS02625	COG1247	-acetyltransferase
NZ30_RS02635	COG1490	D-aminoacyl-tRNA deacylase activity
NZ30_RS02640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NZ30_RS02680	COG1609	Transcriptional regulator
NZ30_RS02690	COG0366	Alpha amylase catalytic
NZ30_RS02695	COG0366	Alpha amylase catalytic
NZ30_RS02750	COG1309	transcriptional regulator
NZ30_RS02785	COG0840	transmembrane signaling receptor activity
NZ30_RS02800	COG3546	catalase activity
NZ30_RS02805	COG3685	Protein conserved in bacteria
NZ30_RS02810	COG3685	Protein conserved in bacteria
NZ30_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS02825	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NZ30_RS02840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NZ30_RS02855	COG0028	Belongs to the TPP enzyme family
NZ30_RS02860	COG4191	Histidine kinase
NZ30_RS02895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NZ30_RS02900	COG0732	type I restriction modification DNA specificity domain
NZ30_RS02910	COG3645	SOS response
NZ30_RS02940	COG1116	anion transmembrane transporter activity
NZ30_RS02940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NZ30_RS02945	COG2223	nitrite transmembrane transporter activity
NZ30_RS02950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NZ30_RS02955	COG2146	nitrite reductase [NAD(P)H] activity
NZ30_RS02960	COG0243	molybdopterin cofactor binding
NZ30_RS02985	COG1640	4-alpha-glucanotransferase
NZ30_RS02990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NZ30_RS03010	COG0745	RESPONSE REGULATOR receiver
NZ30_RS03035	COG0181	hydroxymethylbilane synthase activity
NZ30_RS03050	COG1733	regulation of RNA biosynthetic process
NZ30_RS03065	COG1505	serine-type exopeptidase activity
NZ30_RS03080	COG0436	Aminotransferase
NZ30_RS03090	COG2832	Protein of unknown function (DUF454)
NZ30_RS03100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NZ30_RS03120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NZ30_RS03145	COG2226	methyltransferase
NZ30_RS03150	COG0308	aminopeptidase N
NZ30_RS03155	COG0508	dehydrogenase complex catalyzes the overall conversion of
NZ30_RS03155	COG0596	Alpha beta hydrolase
NZ30_RS03175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZ30_RS03180	COG1077	Cell shape determining protein MreB Mrl
NZ30_RS03185	COG1792	Involved in formation and maintenance of cell shape
NZ30_RS03195	COG0768	penicillin binding
NZ30_RS03200	COG0772	Belongs to the SEDS family
NZ30_RS03215	COG2951	lytic endotransglycosylase activity
NZ30_RS03225	COG1686	Belongs to the peptidase S11 family
NZ30_RS03260	COG0321	lipoyl(octanoyl) transferase activity
NZ30_RS03265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NZ30_RS03290	COG1051	belongs to the nudix hydrolase family
NZ30_RS03290	COG1056	cytidyltransferase-related domain
NZ30_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NZ30_RS03330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NZ30_RS03335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NZ30_RS03340	COG1561	YicC-like family, N-terminal region
NZ30_RS03345	COG0194	GDP metabolic process
NZ30_RS03350	COG1758	RNA polymerase activity
NZ30_RS03355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NZ30_RS03375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NZ30_RS03390	COG0254	rRNA binding
NZ30_RS03410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NZ30_RS03430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NZ30_RS03435	COG0667	Aldo Keto reductase
NZ30_RS03445	COG4771	TonB-dependent receptor
NZ30_RS03465	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NZ30_RS03470	COG4181	ATPase activity
NZ30_RS03485	COG0642	Histidine kinase
NZ30_RS03495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NZ30_RS03500	COG0861	Integral membrane protein TerC family
NZ30_RS03505	COG1704	LemA family
NZ30_RS03535	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NZ30_RS03540	COG2967	ApaG domain
NZ30_RS03545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NZ30_RS03550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NZ30_RS03555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NZ30_RS03560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NZ30_RS03575	COG2096	Adenosyltransferase
NZ30_RS03585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NZ30_RS03590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NZ30_RS03630	COG0697	spore germination
NZ30_RS03635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NZ30_RS03665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NZ30_RS03670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NZ30_RS03680	COG0583	DNA-binding transcription factor activity
NZ30_RS03685	COG3634	alkyl hydroperoxide reductase activity
NZ30_RS03720	COG0488	(ABC) transporter
NZ30_RS03765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NZ30_RS03770	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NZ30_RS03785	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NZ30_RS03795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NZ30_RS03805	COG0193	aminoacyl-tRNA hydrolase activity
NZ30_RS03810	COG0012	GTP binding
NZ30_RS03830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NZ30_RS03840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NZ30_RS03845	COG0250	Participates in transcription elongation, termination and antitermination
NZ30_RS03850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NZ30_RS03870	COG0222	ribosome binding
NZ30_RS03880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NZ30_RS03895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NZ30_RS03900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NZ30_RS03905	COG0051	transcription antitermination factor activity, RNA binding
NZ30_RS03915	COG0088	Forms part of the polypeptide exit tunnel
NZ30_RS03920	COG0089	rRNA binding
NZ30_RS03925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NZ30_RS03950	COG0255	Belongs to the universal ribosomal protein uL29 family
NZ30_RS03955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NZ30_RS03965	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NZ30_RS03970	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NZ30_RS04000	COG1841	ribosomal large subunit assembly
NZ30_RS04010	COG0201	protein transport
NZ30_RS04035	COG0203	ribosomal protein L17
NZ30_RS04040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NZ30_RS04050	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NZ30_RS04065	COG1217	gtp-binding protein TYPA
NZ30_RS04070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NZ30_RS04080	COG0039	L-malate dehydrogenase activity
NZ30_RS04095	COG0625	glutathione transferase activity
NZ30_RS04140	COG1902	pentaerythritol trinitrate reductase activity
NZ30_RS04140	COG0446	pyridine nucleotide-disulphide oxidoreductase
NZ30_RS04150	COG0667	Aldo Keto reductase
NZ30_RS04170	COG2885	chlorophyll binding
NZ30_RS04190	COG0156	8-amino-7-oxononanoate synthase activity
NZ30_RS04195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NZ30_RS04200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NZ30_RS04205	COG4208	sulfate ABC transporter
NZ30_RS04210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NZ30_RS04230	COG0588	phosphoglycerate mutase activity
NZ30_RS04235	COG0285	dihydrofolate synthase activity
NZ30_RS04255	COG2833	Protein of unknown function (DUF455)
NZ30_RS04260	COG3291	Pkd domain containing protein
NZ30_RS04270	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NZ30_RS04280	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS04285	COG0248	Ppx GppA phosphatase
NZ30_RS04290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NZ30_RS04305	COG4783	chaperone-mediated protein folding
NZ30_RS04320	COG0473	3-isopropylmalate dehydrogenase activity
NZ30_RS04355	COG0544	peptidyl-prolyl cis-trans isomerase activity
NZ30_RS04365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NZ30_RS04405	COG1388	LysM domain
NZ30_RS04405	COG3942	CHAP domain
NZ30_RS04410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZ30_RS04420	COG0328	RNA-DNA hybrid ribonuclease activity
NZ30_RS04425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NZ30_RS04430	COG0631	protein serine/threonine phosphatase activity
NZ30_RS04450	COG0859	PFAM glycosyl transferase family 9
NZ30_RS04460	COG1234	tRNA 3'-trailer cleavage
NZ30_RS04465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NZ30_RS04475	COG0315	cyclic pyranopterin monophosphate synthase activity
NZ30_RS04480	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NZ30_RS04485	COG0314	molybdopterin synthase activity
NZ30_RS04600	COG0537	adenosine 5'-monophosphoramidase activity
NZ30_RS04620	COG0714	Associated with various cellular activities
NZ30_RS04645	COG1399	metal-binding, possibly nucleic acid-binding protein
NZ30_RS04655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZ30_RS04660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NZ30_RS04665	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS04670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NZ30_RS04680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NZ30_RS04685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NZ30_RS04690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NZ30_RS04710	COG4115	mRNA cleavage
NZ30_RS04715	COG2161	toxin-antitoxin pair type II binding
NZ30_RS04750	COG0587	DNA-directed DNA polymerase activity
NZ30_RS04765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NZ30_RS04770	COG0372	Belongs to the citrate synthase family
NZ30_RS04785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NZ30_RS04870	COG2205	protein histidine kinase activity
NZ30_RS04885	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NZ30_RS04890	COG3791	Glutathione-dependent formaldehyde-activating
NZ30_RS04900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NZ30_RS04935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NZ30_RS04955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NZ30_RS05010	COG1162	GTPase activity
NZ30_RS05035	COG2211	Major facilitator Superfamily
NZ30_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS05050	COG2851	Citrate transporter
NZ30_RS05065	COG0642	Histidine kinase
NZ30_RS05085	COG4191	Histidine kinase
NZ30_RS05095	COG1301	dicarboxylic acid transport
NZ30_RS05100	COG0280	phosphate acetyltransferase
NZ30_RS05100	COG0281	malic enzyme
NZ30_RS05150	COG1560	Kdo2-lipid A biosynthetic process
NZ30_RS05155	COG1519	Transferase
NZ30_RS05160	COG1538	Outer membrane efflux protein
NZ30_RS05165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NZ30_RS05175	COG3706	GGDEF domain
NZ30_RS05180	COG0473	3-isopropylmalate dehydrogenase activity
NZ30_RS05185	COG0066	3-isopropylmalate dehydratase activity
NZ30_RS05190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NZ30_RS05200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZ30_RS05220	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NZ30_RS05225	COG0840	transmembrane signaling receptor activity
NZ30_RS05245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NZ30_RS05255	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NZ30_RS05285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NZ30_RS05295	COG0671	phosphoesterase, PA-phosphatase related
NZ30_RS05310	COG1940	carbohydrate kinase activity
NZ30_RS05320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NZ30_RS05340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NZ30_RS05355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NZ30_RS05370	COG1773	rubredoxin
NZ30_RS05385	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NZ30_RS05395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NZ30_RS05420	COG3079	Belongs to the UPF0149 family
NZ30_RS05425	COG0006	proline dipeptidase activity
NZ30_RS05445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NZ30_RS05475	COG0714	Associated with various cellular activities
NZ30_RS05505	COG1301	dicarboxylic acid transport
NZ30_RS05510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NZ30_RS05535	COG0739	heme binding
NZ30_RS05540	COG1376	ErfK ybiS ycfS ynhG family protein
NZ30_RS05565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NZ30_RS05570	COG4149	molybdate abc transporter
NZ30_RS05575	COG0725	ABC transporter, periplasmic molybdate-binding protein
NZ30_RS05585	COG0640	Transcriptional regulator
NZ30_RS05605	COG3047	cAMP biosynthetic process
NZ30_RS05610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NZ30_RS05655	COG0469	pyruvate kinase activity
NZ30_RS05660	COG3588	fructose-bisphosphate aldolase
NZ30_RS05665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NZ30_RS05705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NZ30_RS05735	COG2205	protein histidine kinase activity
NZ30_RS05735	COG2198	Histidine kinase
NZ30_RS05735	COG0784	Response regulator, receiver
NZ30_RS05740	COG1393	Belongs to the ArsC family
NZ30_RS05770	COG0175	sulfate reduction
NZ30_RS05775	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NZ30_RS05780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NZ30_RS05790	COG2895	sulfate adenylyltransferase (ATP) activity
NZ30_RS05790	COG0529	Catalyzes the synthesis of activated sulfate
NZ30_RS05795	COG0840	transmembrane signaling receptor activity
NZ30_RS05815	COG1115	amino acid carrier protein
NZ30_RS05825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NZ30_RS05855	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZ30_RS05870	COG3273	potassium ion transport
NZ30_RS05870	COG0471	metal ion transport
NZ30_RS05880	COG2022	thiamine diphosphate biosynthetic process
NZ30_RS05910	COG0174	glutamine synthetase
NZ30_RS05915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NZ30_RS05925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NZ30_RS05940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NZ30_RS05965	COG3511	phospholipase C
NZ30_RS05975	COG0189	ligase activity
NZ30_RS05985	COG0745	RESPONSE REGULATOR receiver
NZ30_RS06000	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NZ30_RS06065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NZ30_RS06065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NZ30_RS06075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NZ30_RS06090	COG1174	glycine betaine transport
NZ30_RS06095	COG1125	glycine betaine transport
NZ30_RS06105	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NZ30_RS06110	COG0564	pseudouridine synthase activity
NZ30_RS06125	COG4993	Dehydrogenase
NZ30_RS06135	COG3387	PFAM Glycoside hydrolase 15-related
NZ30_RS06160	COG0454	-acetyltransferase
NZ30_RS06190	COG0542	response to heat
NZ30_RS06220	COG0019	diaminopimelate decarboxylase activity
NZ30_RS06225	COG4264	IucA IucC family
NZ30_RS06230	COG2814	Major facilitator Superfamily
NZ30_RS06235	COG4264	IucA IucC family
NZ30_RS06245	COG4772	TonB-dependent receptor
NZ30_RS06255	COG4651	solute:proton antiporter activity
NZ30_RS06255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NZ30_RS06310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZ30_RS06310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZ30_RS06330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NZ30_RS06370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NZ30_RS06375	COG1404	Belongs to the peptidase S8 family
NZ30_RS06385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NZ30_RS06405	COG1295	ribonuclease BN
NZ30_RS06410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZ30_RS06430	COG0521	Mo-molybdopterin cofactor biosynthetic process
NZ30_RS06575	COG4682	membrane
NZ30_RS06700	COG3179	chitinase
NZ30_RS06725	COG3179	chitinase
NZ30_RS06990	COG3537	Alpha-1,2-mannosidase
NZ30_RS07010	COG1472	Belongs to the glycosyl hydrolase 3 family
NZ30_RS07020	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NZ30_RS07025	COG3858	chitin binding
NZ30_RS07025	COG1388	LysM domain
NZ30_RS07040	COG0837	glucose binding
NZ30_RS07050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NZ30_RS07060	COG0494	nUDIX hydrolase
NZ30_RS07065	COG1218	3'(2'),5'-bisphosphate nucleotidase
NZ30_RS07070	COG3956	TIGRFAM MazG family protein
NZ30_RS07075	COG1742	UPF0060 membrane protein
NZ30_RS07080	COG0330	HflC and HflK could
NZ30_RS07150	COG2124	cytochrome p450
NZ30_RS07155	COG2124	cytochrome p450
NZ30_RS07160	COG1141	Ferredoxin
NZ30_RS07165	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS07170	COG2124	cytochrome p450
NZ30_RS07175	COG0142	geranyltranstransferase activity
NZ30_RS07180	COG1657	PFAM Prenyltransferase squalene oxidase
NZ30_RS07190	COG1304	FMN binding
NZ30_RS07230	COG2963	transposase activity
NZ30_RS07245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NZ30_RS07250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZ30_RS07255	COG0463	Glycosyl transferase, family 2
NZ30_RS07260	COG0517	IMP dehydrogenase activity
NZ30_RS07265	COG2982	Protein involved in outer membrane biogenesis
NZ30_RS07270	COG1272	protein, Hemolysin III
NZ30_RS07275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NZ30_RS07285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NZ30_RS07290	COG0626	cystathionine gamma-synthase activity
NZ30_RS07295	COG0527	aspartate kinase activity
NZ30_RS07295	COG0460	homoserine dehydrogenase
NZ30_RS07310	COG1760	l-serine dehydratase
NZ30_RS07325	COG3038	cytochrome b561
NZ30_RS07345	COG2814	Major facilitator Superfamily
NZ30_RS07350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NZ30_RS07360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NZ30_RS07380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NZ30_RS07385	COG0259	pyridoxamine-phosphate oxidase activity
NZ30_RS07425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NZ30_RS07440	COG0519	Catalyzes the synthesis of GMP from XMP
NZ30_RS07455	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NZ30_RS07480	COG0840	transmembrane signaling receptor activity
NZ30_RS07490	COG1113	amino acid transport
NZ30_RS07510	COG2239	Acts as a magnesium transporter
NZ30_RS07515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NZ30_RS07520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZ30_RS07535	COG1660	Displays ATPase and GTPase activities
NZ30_RS07545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZ30_RS07560	COG1137	ATPase activity
NZ30_RS07575	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NZ30_RS07615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NZ30_RS07640	COG0628	permease
NZ30_RS07650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NZ30_RS07655	COG3178	'Phosphotransferase
NZ30_RS07670	COG1555	photosystem II stabilization
NZ30_RS07690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NZ30_RS07695	COG1477	protein flavinylation
NZ30_RS07720	COG4774	siderophore transport
NZ30_RS07725	COG2146	nitrite reductase [NAD(P)H] activity
NZ30_RS07735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NZ30_RS07740	COG0719	Fe-S assembly protein
NZ30_RS07745	COG0396	ATPase activity
NZ30_RS07750	COG0719	Fe-S assembly protein
NZ30_RS07765	COG0693	protein deglycase activity
NZ30_RS07780	COG0739	heme binding
NZ30_RS07795	COG1764	response to oxidative stress
NZ30_RS07805	COG0384	phenazine biosynthesis protein PhzF
NZ30_RS07810	COG0527	aspartate kinase activity
NZ30_RS07835	COG0142	geranyltranstransferase activity
NZ30_RS07840	COG0629	single-stranded DNA binding
NZ30_RS07860	COG3104	oligopeptide transport
NZ30_RS07865	COG1297	OPT oligopeptide transporter protein
NZ30_RS07870	COG1506	peptidase
NZ30_RS07870	COG0823	Involved in the tonB-independent uptake of proteins
NZ30_RS07890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NZ30_RS07895	COG2879	small protein
NZ30_RS07900	COG1966	Carbon starvation protein
NZ30_RS07940	COG2211	Major facilitator Superfamily
NZ30_RS07950	COG2801	Transposase and inactivated derivatives
NZ30_RS07975	COG0835	chemotaxis
NZ30_RS07980	COG0840	transmembrane signaling receptor activity
NZ30_RS07985	COG0840	transmembrane signaling receptor activity
NZ30_RS07990	COG0840	transmembrane signaling receptor activity
NZ30_RS07995	COG0643	Histidine kinase
NZ30_RS07995	COG2198	Histidine kinase
NZ30_RS08025	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NZ30_RS08035	COG2205	protein histidine kinase activity
NZ30_RS08070	COG0735	belongs to the Fur family
NZ30_RS08110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NZ30_RS08115	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NZ30_RS08120	COG2080	2 iron, 2 sulfur cluster binding
NZ30_RS08225	COG1187	pseudouridine synthase activity
NZ30_RS08250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NZ30_RS08270	COG1132	(ABC) transporter
NZ30_RS08290	COG2963	transposase activity
NZ30_RS08300	COG2801	Transposase and inactivated derivatives
NZ30_RS08390	COG1981	membrane
NZ30_RS08415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NZ30_RS08420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NZ30_RS08430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NZ30_RS08440	COG0750	zinc metalloprotease
NZ30_RS08445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NZ30_RS08450	COG0575	Belongs to the CDS family
NZ30_RS08455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NZ30_RS08465	COG0528	UMP kinase activity
NZ30_RS08475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NZ30_RS08515	COG0024	Methionine aminopeptidase
NZ30_RS08530	COG1393	Belongs to the ArsC family
NZ30_RS08535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NZ30_RS08545	COG0367	asparagine synthase
NZ30_RS08585	COG1566	PFAM secretion protein HlyD family protein
NZ30_RS08590	COG2814	Major facilitator Superfamily
NZ30_RS08625	COG0557	exoribonuclease II activity
NZ30_RS08635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NZ30_RS08655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NZ30_RS08675	COG0704	Plays a role in the regulation of phosphate uptake
NZ30_RS08685	COG0581	inorganic phosphate transmembrane transporter activity
NZ30_RS08695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NZ30_RS08700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NZ30_RS08720	COG0659	secondary active sulfate transmembrane transporter activity
NZ30_RS08725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NZ30_RS08735	COG1024	Enoyl-CoA hydratase
NZ30_RS08795	COG5002	protein histidine kinase activity
NZ30_RS08795	COG0784	Response regulator, receiver
NZ30_RS08795	COG2205	protein histidine kinase activity
NZ30_RS08800	COG2733	membrane
NZ30_RS08820	COG0686	Belongs to the AlaDH PNT family
NZ30_RS08825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NZ30_RS08830	COG1396	sequence-specific DNA binding
NZ30_RS08830	COG1917	Cupin 2, conserved barrel domain protein
NZ30_RS08835	COG1012	belongs to the aldehyde dehydrogenase family
NZ30_RS08855	COG2223	nitrite transmembrane transporter activity
NZ30_RS08865	COG0243	molybdopterin cofactor binding
NZ30_RS08885	COG0477	Major facilitator Superfamily
NZ30_RS08895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZ30_RS08900	COG0174	glutamine synthetase
NZ30_RS08905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NZ30_RS08910	COG0174	glutamine synthetase
NZ30_RS08950	COG3842	ATPase activity
NZ30_RS08955	COG1176	ABC-type spermidine putrescine transport system, permease component I
NZ30_RS08960	COG1177	transmembrane transport
NZ30_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
NZ30_RS08980	COG4535	Mg2 and Co2 transporter CorC
NZ30_RS08995	COG1702	phosphate starvation-inducible protein PhoH
NZ30_RS09015	COG0723	plastoquinol--plastocyanin reductase activity
NZ30_RS09020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NZ30_RS09025	COG2857	Cytochrome c1
NZ30_RS09030	COG0625	glutathione transferase activity
NZ30_RS09035	COG2969	positive regulation of protein catabolic process
NZ30_RS09050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NZ30_RS09095	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NZ30_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS09105	COG2095	MarC family integral membrane protein
NZ30_RS09115	COG1611	Belongs to the LOG family
NZ30_RS09120	COG3275	phosphorelay sensor kinase activity
NZ30_RS09210	COG2925	Exonuclease
NZ30_RS09220	COG3844	kynureninase activity
NZ30_RS09235	COG0288	reversible hydration of carbon dioxide
NZ30_RS09280	COG2197	response regulator
NZ30_RS09305	COG0316	Belongs to the HesB IscA family
NZ30_RS09340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NZ30_RS09345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NZ30_RS09350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NZ30_RS09360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NZ30_RS09395	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NZ30_RS09410	COG1228	amidohydrolase
NZ30_RS09425	COG4221	oxidoreductase activity
NZ30_RS09465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NZ30_RS09470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NZ30_RS09475	COG0077	Prephenate dehydratase
NZ30_RS09475	COG1605	Chorismate mutase
NZ30_RS09500	COG0583	DNA-binding transcription factor activity
NZ30_RS09545	COG2801	Transposase and inactivated derivatives
NZ30_RS09620	COG0556	nucleotide-excision repair
NZ30_RS09635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NZ30_RS09640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NZ30_RS09650	COG2902	Dehydrogenase
NZ30_RS09680	COG1294	oxidase, subunit
NZ30_RS09690	COG4988	ABC transporter
NZ30_RS09695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NZ30_RS09700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NZ30_RS09745	COG4133	protoheme IX ABC transporter activity
NZ30_RS09750	COG0436	Aminotransferase
NZ30_RS09775	COG1187	pseudouridine synthase activity
NZ30_RS09780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NZ30_RS09785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NZ30_RS09790	COG2350	Protein conserved in bacteria
NZ30_RS09825	COG0395	ABC-type sugar transport system, permease component
NZ30_RS09840	COG0129	dihydroxy-acid dehydratase activity
NZ30_RS09855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NZ30_RS09875	COG2009	succinate dehydrogenase
NZ30_RS09880	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NZ30_RS09890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NZ30_RS09895	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NZ30_RS09905	COG4591	ABC-type transport system involved in lipoprotein release permease component
NZ30_RS09925	COG0811	peptide transport
NZ30_RS09935	COG1132	(ABC) transporter
NZ30_RS09940	COG1663	tetraacyldisaccharide 4'-kinase activity
NZ30_RS09950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZ30_RS09965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NZ30_RS10000	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NZ30_RS10005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NZ30_RS10015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NZ30_RS10055	COG1132	(ABC) transporter
NZ30_RS10085	COG1530	ribonuclease E activity
NZ30_RS10100	COG0428	transporter
NZ30_RS10115	COG0316	Belongs to the HesB IscA family
NZ30_RS10115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NZ30_RS10155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NZ30_RS10160	COG2957	Belongs to the agmatine deiminase family
NZ30_RS10170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NZ30_RS10175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NZ30_RS10180	COG0539	negative regulation of cytoplasmic translation
NZ30_RS10185	COG0776	regulation of translation
NZ30_RS10195	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NZ30_RS10200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NZ30_RS10210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NZ30_RS10215	COG0183	Belongs to the thiolase family
NZ30_RS10220	COG1250	3-hydroxyacyl-CoA dehydrogenase
NZ30_RS10220	COG1024	Enoyl-CoA hydratase
NZ30_RS10235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NZ30_RS10245	COG1426	Protein conserved in bacteria
NZ30_RS10255	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NZ30_RS10265	COG0746	molybdenum cofactor guanylyltransferase activity
NZ30_RS10275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NZ30_RS10280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NZ30_RS10280	COG0475	glutathione-regulated potassium exporter activity
NZ30_RS10300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NZ30_RS10310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NZ30_RS10310	COG0519	Catalyzes the synthesis of GMP from XMP
NZ30_RS10315	COG1501	Belongs to the glycosyl hydrolase 31 family
NZ30_RS10320	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NZ30_RS10330	COG1914	H( )-stimulated, divalent metal cation uptake system
NZ30_RS10340	COG0590	tRNA wobble adenosine to inosine editing
NZ30_RS10345	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NZ30_RS10350	COG0668	transmembrane transport
NZ30_RS10360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NZ30_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS10380	COG1183	phosphatidylcholine synthase activity
NZ30_RS10390	COG3243	poly(R)-hydroxyalkanoic acid synthase
NZ30_RS10410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NZ30_RS10410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZ30_RS10420	COG0784	Response regulator, receiver
NZ30_RS10420	COG4191	Histidine kinase
NZ30_RS10425	COG2183	response to ionizing radiation
NZ30_RS10495	COG1649	PFAM Uncharacterised BCR, COG1649
NZ30_RS10500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NZ30_RS10505	COG1304	FMN binding
NZ30_RS10515	COG0346	lactoylglutathione lyase activity
NZ30_RS10570	COG1024	Enoyl-CoA hydratase
NZ30_RS10575	COG1024	Enoyl-CoA hydratase
NZ30_RS10585	COG1024	Enoyl-CoA hydratase
NZ30_RS10600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZ30_RS10605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZ30_RS10760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NZ30_RS10765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NZ30_RS10775	COG0505	Belongs to the CarA family
NZ30_RS10790	COG2258	MOSC domain
NZ30_RS10795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NZ30_RS10810	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS10815	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS10835	COG4106	trans-aconitate 2-methyltransferase activity
NZ30_RS10855	COG2244	polysaccharide biosynthetic process
NZ30_RS10885	COG3038	cytochrome b561
NZ30_RS10905	COG1595	DNA-templated transcription, initiation
NZ30_RS10960	COG0038	chloride channel
NZ30_RS10965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NZ30_RS10985	COG1674	ftsk spoiiie
NZ30_RS10990	COG0492	ferredoxin-NADP+ reductase activity
NZ30_RS11000	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NZ30_RS11010	COG0542	response to heat
NZ30_RS11030	COG0482	sulfurtransferase activity
NZ30_RS11035	COG2915	High frequency lysogenization protein hflD homolog
NZ30_RS11095	COG0784	Response regulator, receiver
NZ30_RS11095	COG0835	chemotaxis
NZ30_RS11105	COG1558	bacterial-type flagellum-dependent cell motility
NZ30_RS11115	COG1749	Flagellar hook protein flgE
NZ30_RS11130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NZ30_RS11145	COG4786	Flagellar basal body rod
NZ30_RS11145	COG4786	Flagellar basal body rod
NZ30_RS11145	COG1256	bacterial-type flagellum assembly
NZ30_RS11145	COG1256	bacterial-type flagellum assembly
NZ30_RS11155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NZ30_RS11160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NZ30_RS11180	COG2197	response regulator
NZ30_RS11190	COG2201	protein-glutamate methylesterase activity
NZ30_RS11210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZ30_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS11260	COG1677	Flagellar hook-basal body complex protein FliE
NZ30_RS11310	COG3190	flagellar
NZ30_RS11320	COG1987	bacterial-type flagellum assembly
NZ30_RS11325	COG1684	flagellar biosynthetic protein fliR
NZ30_RS11370	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NZ30_RS11375	COG2198	Histidine kinase
NZ30_RS11375	COG0784	Response regulator, receiver
NZ30_RS11375	COG0643	Histidine kinase
NZ30_RS11380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NZ30_RS11390	COG1192	Involved in chromosome partitioning
NZ30_RS11395	COG0835	chemotaxis
NZ30_RS11405	COG0745	RESPONSE REGULATOR receiver
NZ30_RS11420	COG0840	transmembrane signaling receptor activity
NZ30_RS11425	COG0840	transmembrane signaling receptor activity
NZ30_RS11430	COG0840	transmembrane signaling receptor activity
NZ30_RS11435	COG0840	transmembrane signaling receptor activity
NZ30_RS11445	COG0840	transmembrane signaling receptor activity
NZ30_RS11450	COG0840	transmembrane signaling receptor activity
NZ30_RS11455	COG0840	transmembrane signaling receptor activity
NZ30_RS11460	COG0840	transmembrane signaling receptor activity
NZ30_RS11470	COG0840	transmembrane signaling receptor activity
NZ30_RS11480	COG0835	chemotaxis
NZ30_RS11490	COG0840	transmembrane signaling receptor activity
NZ30_RS11500	COG0840	transmembrane signaling receptor activity
NZ30_RS11555	COG0318	PFAM AMP-dependent synthetase and ligase
NZ30_RS11560	COG1024	Enoyl-CoA hydratase
NZ30_RS11565	COG2205	protein histidine kinase activity
NZ30_RS11565	COG2198	Histidine kinase
NZ30_RS11565	COG0784	Response regulator, receiver
NZ30_RS11600	COG0800	Aldolase
NZ30_RS11615	COG3734	2-keto-3-deoxy-galactonokinase
NZ30_RS11620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NZ30_RS11630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NZ30_RS11640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NZ30_RS11645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NZ30_RS11660	COG2201	protein-glutamate methylesterase activity
NZ30_RS11675	COG0352	thiamine-phosphate diphosphorylase activity
NZ30_RS11675	COG0351	phosphomethylpyrimidine kinase
NZ30_RS11695	COG0583	DNA-binding transcription factor activity
NZ30_RS11700	COG1741	Belongs to the pirin family
NZ30_RS11725	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NZ30_RS11735	COG2137	regulation of response to DNA damage stimulus
NZ30_RS11740	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NZ30_RS11745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NZ30_RS11750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NZ30_RS11755	COG1546	Belongs to the CinA family
NZ30_RS11760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NZ30_RS11770	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NZ30_RS11775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NZ30_RS11780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NZ30_RS11785	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NZ30_RS11790	COG1534	Rna-binding protein
NZ30_RS11810	COG1238	metal cluster binding
NZ30_RS11820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NZ30_RS11835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NZ30_RS11840	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NZ30_RS11890	COG0306	phosphate transporter
NZ30_RS11900	COG1253	flavin adenine dinucleotide binding
NZ30_RS11910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NZ30_RS11945	COG0069	glutamate synthase activity
NZ30_RS11950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NZ30_RS11960	COG1609	Transcriptional regulator
NZ30_RS11965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZ30_RS11965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NZ30_RS11970	COG1105	Belongs to the carbohydrate kinase PfkB family
NZ30_RS11975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NZ30_RS11975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NZ30_RS12005	COG0577	efflux transmembrane transporter activity
NZ30_RS12005	COG1136	(ABC) transporter
NZ30_RS12060	COG1960	acyl-CoA dehydrogenase activity
NZ30_RS12065	COG2226	methyltransferase
NZ30_RS12070	COG1410	methionine synthase
NZ30_RS12070	COG0646	methionine synthase
NZ30_RS12075	COG0646	methionine synthase
NZ30_RS12075	COG1410	methionine synthase
NZ30_RS12095	COG2900	Belongs to the SlyX family
NZ30_RS12110	COG0386	Belongs to the glutathione peroxidase family
NZ30_RS12120	COG1725	Transcriptional regulator
NZ30_RS12125	COG1131	(ABC) transporter
NZ30_RS12170	COG2885	chlorophyll binding
NZ30_RS12175	COG2850	peptidyl-arginine hydroxylation
NZ30_RS12225	COG1132	(ABC) transporter
NZ30_RS12235	COG0287	Prephenate dehydrogenase
NZ30_RS12235	COG1605	Chorismate mutase
NZ30_RS12240	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NZ30_RS12245	COG0484	heat shock protein binding
NZ30_RS12250	COG0443	Heat shock 70 kDa protein
NZ30_RS12255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NZ30_RS12260	COG1420	regulation of RNA biosynthetic process
NZ30_RS12265	COG0497	DNA recombination
NZ30_RS12270	COG0735	belongs to the Fur family
NZ30_RS12275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NZ30_RS12285	COG2867	negative regulation of translational initiation
NZ30_RS12290	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NZ30_RS12300	COG1404	Belongs to the peptidase S8 family
NZ30_RS12335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NZ30_RS12350	COG0583	DNA-binding transcription factor activity
NZ30_RS12365	COG0415	Belongs to the DNA photolyase family
NZ30_RS12370	COG0305	Participates in initiation and elongation during chromosome replication
NZ30_RS12380	COG1960	acyl-CoA dehydrogenase activity
NZ30_RS12395	COG0084	hydrolase, TatD family'
NZ30_RS12400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NZ30_RS12450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NZ30_RS12475	COG0386	Belongs to the glutathione peroxidase family
NZ30_RS12485	COG1846	Transcriptional regulator
NZ30_RS12530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NZ30_RS12535	COG4290	ribonuclease
NZ30_RS12545	COG0488	(ABC) transporter
NZ30_RS12550	COG0513	Belongs to the DEAD box helicase family
NZ30_RS12575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NZ30_RS12580	COG0657	acetylesterase activity
NZ30_RS12585	COG0625	glutathione transferase activity
NZ30_RS12595	COG0564	pseudouridine synthase activity
NZ30_RS12600	COG4681	YaeQ
NZ30_RS12605	COG2081	HI0933 family
NZ30_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS12645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NZ30_RS12650	COG0860	N-Acetylmuramoyl-L-alanine amidase
NZ30_RS12655	COG0802	atpase or kinase
NZ30_RS12660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NZ30_RS12660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NZ30_RS12665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NZ30_RS12705	COG1960	acyl-CoA dehydrogenase activity
NZ30_RS12715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NZ30_RS12740	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS12750	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS12755	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS12805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NZ30_RS12810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NZ30_RS12820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NZ30_RS12850	COG1024	Enoyl-CoA hydratase
NZ30_RS12865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NZ30_RS12885	COG0277	FAD linked oxidase domain protein
NZ30_RS12890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NZ30_RS12905	COG0531	amino acid
NZ30_RS12910	COG0531	amino acid
NZ30_RS12915	COG0235	Class ii aldolase
NZ30_RS12920	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NZ30_RS12925	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
NZ30_RS12940	COG0140	phosphoribosyl-ATP diphosphatase activity
NZ30_RS12940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NZ30_RS12955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NZ30_RS12970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NZ30_RS12975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NZ30_RS12985	COG0124	histidyl-tRNA synthetase
NZ30_RS12990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NZ30_RS13000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NZ30_RS13010	COG2951	lytic endotransglycosylase activity
NZ30_RS13015	COG0083	homoserine kinase activity
NZ30_RS13020	COG0460	homoserine dehydrogenase
NZ30_RS13020	COG0527	aspartate kinase activity
NZ30_RS13115	COG1196	nuclear chromosome segregation
NZ30_RS13195	COG3728	DNA packaging
NZ30_RS13195	COG5484	DNA packaging
NZ30_RS13260	COG0270	DNA (cytosine-5-)-methyltransferase activity
NZ30_RS13275	COG0305	Participates in initiation and elongation during chromosome replication
NZ30_RS13415	COG1012	belongs to the aldehyde dehydrogenase family
NZ30_RS13430	COG0167	dihydroorotate dehydrogenase activity
NZ30_RS13435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NZ30_RS13460	COG0671	phosphoesterase, PA-phosphatase related
NZ30_RS13475	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NZ30_RS13585	COG0166	Belongs to the GPI family
NZ30_RS13600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NZ30_RS13610	COG0617	tRNA 3'-terminal CCA addition
NZ30_RS13630	COG0860	N-Acetylmuramoyl-L-alanine amidase
NZ30_RS13635	COG0477	Major facilitator Superfamily
NZ30_RS13640	COG2115	Belongs to the xylose isomerase family
NZ30_RS13645	COG1070	Carbohydrate kinase
NZ30_RS13665	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NZ30_RS13685	COG0165	Argininosuccinate lyase
NZ30_RS13690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NZ30_RS13700	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NZ30_RS13705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NZ30_RS13710	COG0137	argininosuccinate synthase activity
NZ30_RS13715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NZ30_RS13730	COG2166	iron-sulfur cluster assembly
NZ30_RS13800	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NZ30_RS13810	COG4677	pectinesterase activity
NZ30_RS13820	COG4677	pectinesterase activity
NZ30_RS13840	COG0402	S-adenosylhomocysteine deaminase activity
NZ30_RS13845	COG3548	integral membrane protein
NZ30_RS13855	COG1509	lysine 2,3-aminomutase activity
NZ30_RS13860	COG4251	negative regulation of phosphorylation
NZ30_RS13860	COG5001	Diguanylate cyclase
NZ30_RS13860	COG3706	GGDEF domain
NZ30_RS13860	COG2203	Gaf domain
NZ30_RS13885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NZ30_RS13890	COG1862	Preprotein translocase
NZ30_RS13900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NZ30_RS13910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NZ30_RS13920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NZ30_RS13925	COG3291	Pkd domain containing protein
NZ30_RS13930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZ30_RS13935	COG0405	Gamma-glutamyltransferase
NZ30_RS13940	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NZ30_RS13955	COG0742	ribosomal rna small subunit methyltransferase
NZ30_RS13980	COG4771	TonB-dependent receptor
NZ30_RS13990	COG3507	Belongs to the glycosyl hydrolase 43 family
NZ30_RS14030	COG0531	amino acid
NZ30_RS14055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NZ30_RS14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZ30_RS14075	COG3938	Belongs to the proline racemase family
NZ30_RS14085	COG0552	protein localization to endoplasmic reticulum
NZ30_RS14090	COG1194	a g-specific adenine glycosylase
NZ30_RS14130	COG0582	viral genome integration into host DNA
NZ30_RS14160	COG0835	chemotaxis
NZ30_RS14165	COG0840	transmembrane signaling receptor activity
NZ30_RS14170	COG0840	transmembrane signaling receptor activity
NZ30_RS14190	COG3300	MHYT domain
NZ30_RS14190	COG5001	Diguanylate cyclase
NZ30_RS14195	COG1185	polyribonucleotide nucleotidyltransferase activity
NZ30_RS14220	COG0195	Participates in both transcription termination and antitermination
NZ30_RS14235	COG1007	ATP synthesis coupled electron transport
NZ30_RS14250	COG0713	ATP synthesis coupled electron transport
NZ30_RS14270	COG1034	ATP synthesis coupled electron transport
NZ30_RS14275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NZ30_RS14280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NZ30_RS14285	COG0649	NAD binding
NZ30_RS14290	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NZ30_RS14300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NZ30_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS14350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NZ30_RS14395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NZ30_RS14410	COG2890	protein-(glutamine-N5) methyltransferase activity
NZ30_RS14420	COG0688	phosphatidylethanolamine metabolic process
NZ30_RS14425	COG0741	lytic transglycosylase activity
NZ30_RS14430	COG0433	COG0433 Predicted ATPase
NZ30_RS14435	COG0494	nUDIX hydrolase
NZ30_RS14450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NZ30_RS14470	COG1714	RDD family
NZ30_RS14475	COG0717	Belongs to the dCTP deaminase family
NZ30_RS14480	COG0489	protein tyrosine kinase activity
NZ30_RS14490	COG4771	TonB-dependent receptor
NZ30_RS14495	COG4771	TonB-dependent receptor
NZ30_RS14500	COG0457	Tetratricopeptide repeat
NZ30_RS14515	COG3590	peptidase
NZ30_RS14545	COG0697	spore germination
NZ30_RS14565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZ30_RS14570	COG2311	Membrane
NZ30_RS14575	COG1047	Peptidyl-prolyl cis-trans
NZ30_RS14580	COG0791	NLP P60 protein
NZ30_RS14585	COG0791	NLP P60 protein
NZ30_RS14600	COG1607	acyl-coa hydrolase
NZ30_RS14610	COG1301	dicarboxylic acid transport
NZ30_RS14615	COG1785	Belongs to the alkaline phosphatase family
NZ30_RS14625	COG0037	tRNA processing
NZ30_RS14630	COG1722	exodeoxyribonuclease VII activity
NZ30_RS14635	COG0142	geranyltranstransferase activity
NZ30_RS14645	COG1858	cytochrome C peroxidase
NZ30_RS14670	COG2815	serine threonine protein kinase
NZ30_RS14670	COG0515	serine threonine protein kinase
NZ30_RS14675	COG0631	protein serine/threonine phosphatase activity
NZ30_RS14770	COG0312	modulator of DNA gyrase
NZ30_RS14780	COG0312	modulator of DNA gyrase
NZ30_RS14800	COG2968	Membrane
NZ30_RS14815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NZ30_RS14830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NZ30_RS14845	COG0495	leucyl-tRNA aminoacylation
NZ30_RS14855	COG3118	belongs to the thioredoxin family
NZ30_RS14875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NZ30_RS14885	COG2040	homocysteine
NZ30_RS14890	COG0833	amino acid
NZ30_RS14900	COG0346	lactoylglutathione lyase activity
NZ30_RS14925	COG2878	Part of a membrane complex involved in electron transport
NZ30_RS14940	COG1595	DNA-templated transcription, initiation
NZ30_RS14965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NZ30_RS14985	COG0251	oxidation-reduction process
NZ30_RS14995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NZ30_RS14995	COG0392	lysyltransferase activity
NZ30_RS15025	COG2814	Major facilitator Superfamily
NZ30_RS15030	COG1902	pentaerythritol trinitrate reductase activity
NZ30_RS15035	COG2824	Alkylphosphonate utilization operon protein PhnA
NZ30_RS15040	COG1047	Peptidyl-prolyl cis-trans
NZ30_RS15045	COG1077	Cell shape determining protein MreB Mrl
NZ30_RS15080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NZ30_RS15090	COG1451	nucleotide metabolic process
NZ30_RS15115	COG0784	Response regulator, receiver
NZ30_RS15115	COG2198	Histidine kinase
NZ30_RS15115	COG2205	protein histidine kinase activity
NZ30_RS15125	COG2186	Transcriptional regulator
NZ30_RS15185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NZ30_RS15185	COG1703	isobutyryl-CoA mutase activity
NZ30_RS15185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NZ30_RS15215	COG0183	Belongs to the thiolase family
NZ30_RS15225	COG0443	Heat shock 70 kDa protein
NZ30_RS15255	COG1793	dna ligase
NZ30_RS15255	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NZ30_RS15260	COG1793	dna ligase
NZ30_RS15260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NZ30_RS15265	COG1201	RNA secondary structure unwinding
NZ30_RS15275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NZ30_RS15280	COG1278	Cold shock
NZ30_RS15285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NZ30_RS15290	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NZ30_RS15295	COG1472	Belongs to the glycosyl hydrolase 3 family
NZ30_RS15305	COG2954	triphosphatase activity
NZ30_RS15315	COG0745	RESPONSE REGULATOR receiver
NZ30_RS15330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NZ30_RS15345	COG0681	Belongs to the peptidase S26 family
NZ30_RS15355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZ30_RS15385	COG2855	membrane
NZ30_RS15400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NZ30_RS15420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NZ30_RS15430	COG0534	Mate efflux family protein
NZ30_RS15435	COG0335	large ribosomal subunit rRNA binding
NZ30_RS15440	COG0336	Belongs to the RNA methyltransferase TrmD family
NZ30_RS15445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NZ30_RS15460	COG2070	2-Nitropropane dioxygenase
NZ30_RS15465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NZ30_RS15490	COG0475	glutathione-regulated potassium exporter activity
NZ30_RS15500	COG0625	glutathione transferase activity
NZ30_RS15505	COG1082	Xylose isomerase domain protein TIM barrel
NZ30_RS15515	COG1172	Belongs to the binding-protein-dependent transport system permease family
NZ30_RS15520	COG1172	Belongs to the binding-protein-dependent transport system permease family
NZ30_RS15525	COG1129	ABC transporter
NZ30_RS15530	COG1879	ABC-type sugar transport system periplasmic component
NZ30_RS15535	COG1012	belongs to the aldehyde dehydrogenase family
NZ30_RS15555	COG0129	dihydroxy-acid dehydratase activity
NZ30_RS15585	COG2207	Transcriptional regulator
NZ30_RS15605	COG1317	bacterial-type flagellum organization
NZ30_RS15630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NZ30_RS15655	COG4794	Type iii secretion
NZ30_RS15685	COG0745	RESPONSE REGULATOR receiver
NZ30_RS15715	COG3152	Membrane
NZ30_RS15725	COG0156	8-amino-7-oxononanoate synthase activity
NZ30_RS15735	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NZ30_RS15740	COG1845	cytochrome c oxidase, subunit III
NZ30_RS15745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NZ30_RS15765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NZ30_RS15780	COG0196	riboflavin kinase activity
NZ30_RS15800	COG0728	peptidoglycan biosynthetic process
NZ30_RS15820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NZ30_RS15825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NZ30_RS15830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NZ30_RS15835	COG0824	Thioesterase
NZ30_RS15850	COG1024	Enoyl-CoA hydratase
NZ30_RS15855	COG1946	Acyl-CoA thioesterase
NZ30_RS15865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NZ30_RS15870	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NZ30_RS15885	COG4638	Rieske (2fe-2S)
NZ30_RS15930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NZ30_RS15980	COG1643	Atp-dependent helicase
NZ30_RS15985	COG0783	Belongs to the Dps family
NZ30_RS15990	COG0514	ATP-dependent DNA helicase (RecQ)
NZ30_RS16010	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NZ30_RS16015	COG0602	queuosine metabolic process
NZ30_RS16025	COG2885	chlorophyll binding
NZ30_RS16040	COG0848	biopolymer transport protein
NZ30_RS16050	COG0824	Thioesterase
NZ30_RS16055	COG2255	four-way junction helicase activity
NZ30_RS16060	COG3158	transport of potassium into the cell
NZ30_RS16065	COG0632	four-way junction helicase activity
NZ30_RS16075	COG0217	transcriptional regulatory protein
NZ30_RS16095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NZ30_RS16115	COG3142	Participates in the control of copper homeostasis
NZ30_RS16120	COG1446	asparaginase
NZ30_RS16135	COG2201	protein-glutamate methylesterase activity
NZ30_RS16140	COG0784	Response regulator, receiver
NZ30_RS16140	COG2198	Histidine kinase
NZ30_RS16140	COG0643	Histidine kinase
NZ30_RS16145	COG0840	transmembrane signaling receptor activity
NZ30_RS16150	COG0835	chemotaxis
NZ30_RS16165	COG0189	ligase activity
NZ30_RS16185	COG1199	ATP-dependent helicase activity
NZ30_RS16195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZ30_RS16200	COG1216	Glycosyl transferase, family 2
NZ30_RS16205	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NZ30_RS16225	COG4585	Histidine kinase
NZ30_RS16235	COG0850	regulation of cytokinetic process
NZ30_RS16240	COG2894	cell division
NZ30_RS16245	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NZ30_RS16255	COG2205	protein histidine kinase activity
NZ30_RS16260	COG0745	RESPONSE REGULATOR receiver
NZ30_RS16270	COG2194	sulfuric ester hydrolase activity
NZ30_RS16290	COG2814	Major facilitator Superfamily
NZ30_RS16310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NZ30_RS16310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NZ30_RS16320	COG0753	catalase activity
NZ30_RS16330	COG4106	trans-aconitate 2-methyltransferase activity
NZ30_RS16345	COG1063	alcohol dehydrogenase
NZ30_RS16355	COG3459	Glycosyltransferase 36 associated
NZ30_RS16420	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NZ30_RS16430	COG0330	HflC and HflK could
NZ30_RS16435	COG0330	HflC and HflK could
NZ30_RS16440	COG0604	alcohol dehydrogenase
NZ30_RS16465	COG0678	peroxiredoxin activity
NZ30_RS16475	COG4953	penicillin-binding protein 1C
NZ30_RS16495	COG2373	Large extracellular alpha-helical protein
NZ30_RS16515	COG0617	tRNA 3'-terminal CCA addition
NZ30_RS16525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NZ30_RS16530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NZ30_RS16535	COG1609	Transcriptional regulator
NZ30_RS16540	COG0738	Major facilitator superfamily
NZ30_RS16545	COG2188	Transcriptional regulator
NZ30_RS16560	COG3250	beta-galactosidase activity
NZ30_RS16590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NZ30_RS16600	COG4191	Histidine kinase
NZ30_RS16605	COG0784	Response regulator, receiver
NZ30_RS16610	COG2205	protein histidine kinase activity
NZ30_RS16610	COG2202	Pas domain
NZ30_RS16620	COG2823	Periplasmic or secreted lipoprotein
NZ30_RS16625	COG0673	inositol 2-dehydrogenase activity
NZ30_RS16630	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NZ30_RS16640	COG1090	epimerase
NZ30_RS16655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NZ30_RS16695	COG2226	methyltransferase
NZ30_RS16720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NZ30_RS16730	COG0494	nUDIX hydrolase
NZ30_RS16745	COG0739	heme binding
NZ30_RS16755	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NZ30_RS16760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NZ30_RS16770	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NZ30_RS16775	COG1181	Belongs to the D-alanine--D-alanine ligase family
NZ30_RS16785	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NZ30_RS16800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NZ30_RS16815	COG3116	cell division
NZ30_RS16820	COG0275	rRNA processing
NZ30_RS16825	COG2001	Belongs to the MraZ family
NZ30_RS16860	COG0792	nuclease activity
NZ30_RS16865	COG1988	membrane-bound metal-dependent
NZ30_RS16870	COG0277	FAD linked oxidase domain protein
NZ30_RS16875	COG0745	RESPONSE REGULATOR receiver
NZ30_RS16880	COG2205	protein histidine kinase activity
NZ30_RS16890	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NZ30_RS16895	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NZ30_RS16920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NZ30_RS16925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NZ30_RS16930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NZ30_RS16945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NZ30_RS16945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NZ30_RS16955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NZ30_RS16985	COG0477	Major facilitator Superfamily
NZ30_RS16990	COG0488	(ABC) transporter
NZ30_RS16995	COG0242	peptide deformylase activity
NZ30_RS17020	COG1215	transferase activity, transferring glycosyl groups
NZ30_RS17030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NZ30_RS17085	COG2188	Transcriptional regulator
NZ30_RS17100	COG1450	Type ii and iii secretion system protein
NZ30_RS17115	COG3166	PFAM Fimbrial assembly family protein
NZ30_RS17120	COG3156	type II secretion system protein K
NZ30_RS17125	COG4795	General secretion pathway protein
NZ30_RS17130	COG2165	general secretion pathway protein
NZ30_RS17135	COG4970	Tfp pilus assembly protein FimT
NZ30_RS17140	COG2165	general secretion pathway protein
NZ30_RS17145	COG1459	type II secretion system
NZ30_RS17150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NZ30_RS17155	COG1404	Belongs to the peptidase S8 family
NZ30_RS17160	COG5295	Hep Hag repeat protein
NZ30_RS17170	COG0840	transmembrane signaling receptor activity
NZ30_RS17175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NZ30_RS17175	COG0047	phosphoribosylformylglycinamidine synthase activity
NZ30_RS17180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NZ30_RS17185	COG4974	Belongs to the 'phage' integrase family
NZ30_RS17210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NZ30_RS17215	COG2927	DNA polymerase III (CHI subunit)
NZ30_RS17250	COG1183	phosphatidylcholine synthase activity
NZ30_RS17260	COG0442	prolyl-tRNA aminoacylation
NZ30_RS17275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NZ30_RS17280	COG1127	ABC transporter
NZ30_RS17285	COG3218	ABC-type transport auxiliary lipoprotein component
NZ30_RS17285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NZ30_RS17315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NZ30_RS17320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NZ30_RS17325	COG0662	Cupin 2, conserved barrel domain protein
NZ30_RS17325	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NZ30_RS17350	COG2086	electron transfer activity
NZ30_RS17365	COG0546	phosphoglycolate phosphatase activity
NZ30_RS17365	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NZ30_RS17370	COG0277	FAD linked oxidase domain protein
NZ30_RS17375	COG0300	oxidoreductase activity
NZ30_RS17400	COG0493	'glutamate synthase
NZ30_RS17435	COG1216	Glycosyl transferase, family 2
NZ30_RS17435	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS17440	COG1216	Glycosyl transferase, family 2
NZ30_RS17440	COG0438	transferase activity, transferring glycosyl groups
NZ30_RS17445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NZ30_RS17460	COG0626	cystathionine gamma-synthase activity
NZ30_RS17490	COG0625	glutathione transferase activity
NZ30_RS17505	COG0513	Belongs to the DEAD box helicase family
NZ30_RS17510	COG0720	synthase
NZ30_RS17520	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NZ30_RS17525	COG1956	GAF domain-containing protein
NZ30_RS17535	COG4206	TonB-dependent receptor
NZ30_RS17540	COG0546	phosphoglycolate phosphatase activity
NZ30_RS17545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NZ30_RS17565	COG0339	signal peptide processing
NZ30_RS17580	COG2217	Heavy metal translocating P-type atpase
NZ30_RS17595	COG2132	Multicopper oxidase
NZ30_RS17615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NZ30_RS17625	COG1136	(ABC) transporter
NZ30_RS17630	COG1136	(ABC) transporter
NZ30_RS17630	COG0577	efflux transmembrane transporter activity
NZ30_RS17635	COG0577	efflux transmembrane transporter activity
NZ30_RS17635	COG1136	(ABC) transporter
NZ30_RS17660	COG4191	Histidine kinase
NZ30_RS17670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NZ30_RS17685	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NZ30_RS17700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NZ30_RS17710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NZ30_RS17720	COG0356	it plays a direct role in the translocation of protons across the membrane
NZ30_RS17735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NZ30_RS17740	COG0508	dehydrogenase complex catalyzes the overall conversion of
NZ30_RS17775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NZ30_RS17780	COG0697	spore germination
NZ30_RS17785	COG1666	GTP binding
NZ30_RS17795	COG1187	pseudouridine synthase activity
NZ30_RS17820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NZ30_RS17820	COG2205	protein histidine kinase activity
NZ30_RS17840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZ30_RS17915	COG0842	Transport permease protein
NZ30_RS17920	COG1131	(ABC) transporter
NZ30_RS17925	COG0025	NhaP-type Na H and K H
NZ30_RS17935	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NZ30_RS17940	COG1573	uracil-dna glycosylase
NZ30_RS17955	COG3384	dioxygenase
NZ30_RS17980	COG0667	Aldo Keto reductase
NZ30_RS17990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NZ30_RS17995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NZ30_RS18015	COG3706	GGDEF domain
NZ30_RS18025	COG5001	Diguanylate cyclase
NZ30_RS18055	COG4106	trans-aconitate 2-methyltransferase activity
NZ30_RS18065	COG2076	Multidrug Resistance protein
NZ30_RS18075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NZ30_RS18095	COG3279	Response regulator of the LytR AlgR family
NZ30_RS18100	COG3275	phosphorelay sensor kinase activity
NZ30_RS18125	COG0531	amino acid
NZ30_RS18150	COG0741	lytic transglycosylase activity
NZ30_RS18175	COG2207	Transcriptional regulator
NZ30_RS18185	COG0598	Magnesium transport protein CorA
NZ30_RS18190	COG1113	amino acid transport
NZ30_RS18195	COG0697	spore germination
NZ30_RS18225	COG5520	Belongs to the glycosyl hydrolase 30 family
NZ30_RS18335	COG0840	transmembrane signaling receptor activity
NZ30_RS18350	COG2353	YceI-like domain
NZ30_RS18375	COG0584	glycerophosphoryl diester phosphodiesterase
NZ30_RS18385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NZ30_RS18405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NZ30_RS18410	COG0459	protein refolding
NZ30_RS18425	COG1324	tolerance protein
NZ30_RS18435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZ30_RS18445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NZ30_RS18450	COG0511	ligase activity, forming carbon-carbon bonds
NZ30_RS18455	COG0439	Biotin carboxylase
NZ30_RS18470	COG2264	protein methyltransferase activity
NZ30_RS18495	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NZ30_RS18505	COG4589	Belongs to the CDS family
NZ30_RS18525	COG2267	carboxylic ester hydrolase activity
NZ30_RS18530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NZ30_RS18535	COG0138	bifunctional purine biosynthesis protein purh
NZ30_RS18540	COG0151	Belongs to the GarS family
NZ30_RS18545	COG1289	transmembrane transporter activity
NZ30_RS18550	COG2814	Major facilitator Superfamily
NZ30_RS18590	COG2816	NAD+ diphosphatase activity
NZ30_RS18630	COG2906	2 iron, 2 sulfur cluster binding
NZ30_RS18660	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NZ30_RS18675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NZ30_RS18680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NZ30_RS18685	COG0730	response to heat
NZ30_RS18700	COG0134	indole-3-glycerol-phosphate synthase activity
NZ30_RS18705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NZ30_RS18725	COG1597	lipid kinase activity
NZ30_RS18740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NZ30_RS18755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NZ30_RS18760	COG2111	Na H antiporter
NZ30_RS18760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NZ30_RS18765	COG1006	Multisubunit Na H antiporter MnhC subunit
NZ30_RS18770	COG0651	ATP synthesis coupled electron transport
NZ30_RS18775	COG1863	multisubunit Na H antiporter MnhE subunit
NZ30_RS18780	COG2212	antiporter activity
NZ30_RS18785	COG1320	monovalent cation:proton antiporter activity
NZ30_RS18790	COG0530	calcium, potassium:sodium antiporter activity
NZ30_RS18805	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NZ30_RS18825	COG3104	oligopeptide transport
NZ30_RS18860	COG0508	dehydrogenase complex catalyzes the overall conversion of
NZ30_RS18890	COG0513	Belongs to the DEAD box helicase family
NZ30_RS18915	COG2354	Protein conserved in bacteria
NZ30_RS18935	COG1196	nuclear chromosome segregation
NZ30_RS18935	COG3264	Mechanosensitive ion channel
NZ30_RS18940	COG0604	alcohol dehydrogenase
NZ30_RS18940	COG3321	synthase
NZ30_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS18960	COG1595	DNA-templated transcription, initiation
NZ30_RS18975	COG1802	Transcriptional regulator
NZ30_RS19010	COG3052	prosthetic group binding
NZ30_RS19020	COG1414	Transcriptional regulator
NZ30_RS19025	COG0738	Major facilitator superfamily
NZ30_RS19030	COG3254	rhamnose metabolic process
NZ30_RS19040	COG4948	Mandelate Racemase Muconate Lactonizing
NZ30_RS19045	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZ30_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
NZ30_RS19085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NZ30_RS19100	COG4807	Protein conserved in bacteria
NZ30_RS19140	COG0823	Involved in the tonB-independent uptake of proteins
NZ30_RS19140	COG1506	peptidase
NZ30_RS19245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZ30_RS19265	COG0628	permease
NZ30_RS19270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NZ30_RS19275	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NZ30_RS19280	COG0753	catalase activity
NZ30_RS19305	COG1136	(ABC) transporter
NZ30_RS19310	COG0577	efflux transmembrane transporter activity
NZ30_RS19330	COG0697	spore germination
NZ30_RS19345	COG0180	Tryptophanyl-tRNA synthetase
NZ30_RS19380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NZ30_RS19385	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NZ30_RS19385	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NZ30_RS19395	COG3228	Belongs to the MtfA family
NZ30_RS19425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NZ30_RS19450	COG2084	Dehydrogenase
NZ30_RS19455	COG1902	pentaerythritol trinitrate reductase activity
NZ30_RS19480	COG1404	Belongs to the peptidase S8 family
NZ30_RS19485	COG2814	Major facilitator Superfamily
NZ30_RS19490	COG0583	DNA-binding transcription factor activity
NZ30_RS19510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZ30_RS19515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZ30_RS19530	COG1764	response to oxidative stress
NZ30_RS19535	COG1846	Transcriptional regulator
NZ30_RS19540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NZ30_RS19550	COG0697	spore germination
NZ30_RS19560	COG0523	cobalamin synthesis protein
NZ30_RS19570	COG1742	UPF0060 membrane protein
NZ30_RS19580	COG3245	cytochrome
NZ30_RS19590	COG1960	acyl-CoA dehydrogenase activity
NZ30_RS19595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NZ30_RS19630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NZ30_RS19635	COG3387	PFAM Glycoside hydrolase 15-related
NZ30_RS19640	COG0745	RESPONSE REGULATOR receiver
NZ30_RS19655	COG1404	Belongs to the peptidase S8 family
NZ30_RS19665	COG3100	YcgL domain-containing protein
NZ30_RS19670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NZ30_RS19680	COG0463	Glycosyl transferase, family 2
NZ30_RS19715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NZ30_RS19730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NZ30_RS19755	COG1294	oxidase, subunit
NZ30_RS19760	COG1271	oxidase subunit
NZ30_RS19775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NZ30_RS19780	COG0408	coproporphyrinogen oxidase activity
NZ30_RS19790	COG2323	membrane
NZ30_RS19795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZ30_RS19795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZ30_RS19810	COG0589	response to stress
NZ30_RS19830	COG0210	DNA helicase
NZ30_RS19880	COG0463	Glycosyl transferase, family 2
NZ30_RS19890	COG1475	DNA binding
NZ30_RS19895	COG1192	Involved in chromosome partitioning
NZ30_RS19900	COG0357	Ribosomal RNA small subunit methyltransferase G
NZ30_RS19915	COG2091	lysine biosynthetic process via aminoadipic acid
NZ30_RS19940	COG0477	Major facilitator Superfamily
NZ30_RS19960	COG1971	Probably functions as a manganese efflux pump
NZ30_RS19965	COG2205	protein histidine kinase activity
NZ30_RS19975	COG3459	Glycosyltransferase 36 associated
NZ30_RS19980	COG2211	Major facilitator Superfamily
NZ30_RS20000	COG2911	Protein conserved in bacteria
NZ30_RS20005	COG0729	surface antigen
NZ30_RS20025	COG3132	Protein of unknown function, DUF480
NZ30_RS20070	COG0284	orotidine-5'-phosphate decarboxylase activity
NZ30_RS20085	COG1609	Transcriptional regulator
NZ30_RS20095	COG2937	Belongs to the GPAT DAPAT family
NZ30_RS20120	COG2211	Major facilitator Superfamily
NZ30_RS20135	COG3693	PFAM glycoside hydrolase, family 10
NZ30_RS20155	COG3386	PFAM SMP-30 Gluconolaconase
NZ30_RS20175	COG0246	Mannitol dehydrogenase
NZ30_RS20180	COG1472	Belongs to the glycosyl hydrolase 3 family
NZ30_RS20200	COG3661	Belongs to the glycosyl hydrolase 67 family
NZ30_RS20210	COG2115	Belongs to the xylose isomerase family
NZ30_RS20215	COG0037	tRNA processing
NZ30_RS20235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NZ30_RS20245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NZ30_RS20255	COG0805	protein transport
NZ30_RS20265	COG0519	Catalyzes the synthesis of GMP from XMP
NZ30_RS20265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NZ30_RS20270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NZ30_RS20290	COG0210	DNA helicase
NZ30_RS20295	COG1435	thymidine kinase activity
NZ30_RS20305	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NZ30_RS20315	COG0515	serine threonine protein kinase
NZ30_RS20315	COG0457	Tetratricopeptide repeat
NZ30_RS20330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NZ30_RS20345	COG1119	ATPase activity
NZ30_RS20360	COG0706	membrane insertase activity
NZ30_RS20365	COG0594	ribonuclease P activity