locus-tag	class	description
FD63_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FD63_RS00020	COG0187	DNA topoisomerase II activity
FD63_RS00025	COG1266	CAAX protease self-immunity
FD63_RS00030	COG0501	Belongs to the peptidase M48B family
FD63_RS00075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD63_RS00090	COG1280	lysine exporter protein (LysE YggA)
FD63_RS00105	COG4772	TonB-dependent receptor
FD63_RS00115	COG3284	Transcriptional regulator
FD63_RS00120	COG1012	belongs to the aldehyde dehydrogenase family
FD63_RS00155	COG1304	FMN binding
FD63_RS00160	COG2186	Transcriptional regulator
FD63_RS00180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD63_RS00225	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FD63_RS00245	COG4771	TonB-dependent receptor
FD63_RS00290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FD63_RS00305	COG3507	Belongs to the glycosyl hydrolase 43 family
FD63_RS00310	COG1609	Transcriptional regulator
FD63_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS00335	COG3186	Phenylalanine-4-hydroxylase
FD63_RS00340	COG1522	sequence-specific DNA binding
FD63_RS00365	COG1752	Esterase of the alpha-beta hydrolase superfamily
FD63_RS00390	COG0671	phosphoesterase, PA-phosphatase related
FD63_RS00405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FD63_RS00435	COG1929	Belongs to the glycerate kinase type-1 family
FD63_RS00445	COG0531	amino acid
FD63_RS00450	COG4566	intracellular signal transduction
FD63_RS00455	COG4191	Histidine kinase
FD63_RS00475	COG1322	Protein conserved in bacteria
FD63_RS00480	COG0386	Belongs to the glutathione peroxidase family
FD63_RS00485	COG2853	Lipoprotein
FD63_RS00500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FD63_RS00505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FD63_RS00510	COG1127	ABC transporter
FD63_RS00515	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FD63_RS00520	COG1074	ATP-dependent DNA helicase activity
FD63_RS00525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FD63_RS00545	COG0537	adenosine 5'-monophosphoramidase activity
FD63_RS00610	COG0477	Major facilitator Superfamily
FD63_RS00615	COG0302	gtp cyclohydrolase
FD63_RS00640	COG0730	response to heat
FD63_RS00655	COG0676	glucose-6-phosphate 1-epimerase activity
FD63_RS00715	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_RS00720	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_RS00725	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_RS00730	COG0493	'glutamate synthase
FD63_RS00735	COG0067	glutamate synthase
FD63_RS00735	COG0069	glutamate synthase activity
FD63_RS00735	COG0070	glutamate synthase
FD63_RS00780	COG1111	helicase
FD63_RS00780	COG1205	dead DEAH box helicase
FD63_RS00785	COG2963	transposase activity
FD63_RS00790	COG2801	Transposase and inactivated derivatives
FD63_RS00825	COG2271	Major facilitator Superfamily
FD63_RS00870	COG1192	Involved in chromosome partitioning
FD63_RS00875	COG2062	phosphohistidine phosphatase, SixA
FD63_RS00885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FD63_RS00890	COG2050	protein possibly involved in aromatic compounds catabolism
FD63_RS00900	COG2267	carboxylic ester hydrolase activity
FD63_RS00910	COG1881	PFAM PEBP family protein
FD63_RS00915	COG1968	undecaprenyl-diphosphatase activity
FD63_RS00920	COG0174	glutamine synthetase
FD63_RS00925	COG0347	Belongs to the P(II) protein family
FD63_RS00930	COG0004	ammonium transporteR
FD63_RS00935	COG3852	Histidine kinase
FD63_RS00940	COG2204	response regulator
FD63_RS00945	COG2032	superoxide dismutase activity
FD63_RS00950	COG2032	superoxide dismutase activity
FD63_RS00960	COG0183	Belongs to the thiolase family
FD63_RS01000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FD63_RS01005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FD63_RS01015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FD63_RS01025	COG0612	Peptidase, M16
FD63_RS01035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_RS01045	COG0596	Alpha beta hydrolase
FD63_RS01055	COG0727	PFAM Uncharacterised protein family (UPF0153)
FD63_RS01060	COG0318	PFAM AMP-dependent synthetase and ligase
FD63_RS01075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD63_RS01085	COG1181	Belongs to the D-alanine--D-alanine ligase family
FD63_RS01100	COG4232	protein-disulfide reductase activity
FD63_RS01105	COG0564	pseudouridine synthase activity
FD63_RS01125	COG0339	signal peptide processing
FD63_RS01145	COG0583	DNA-binding transcription factor activity
FD63_RS01150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FD63_RS01155	COG2224	Isocitrate lyase
FD63_RS01190	COG0659	secondary active sulfate transmembrane transporter activity
FD63_RS01225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD63_RS01230	COG2130	NADP-dependent
FD63_RS01245	COG1187	pseudouridine synthase activity
FD63_RS01255	COG1643	Atp-dependent helicase
FD63_RS01260	COG0084	hydrolase, TatD family'
FD63_RS01275	COG0842	Transport permease protein
FD63_RS01280	COG1131	(ABC) transporter
FD63_RS01285	COG0543	2 iron, 2 sulfur cluster binding
FD63_RS01285	COG0633	Ferredoxin
FD63_RS01295	COG1476	TRANSCRIPTIONal
FD63_RS01305	COG4555	ABC transporter
FD63_RS01325	COG0625	glutathione transferase activity
FD63_RS01405	COG1199	ATP-dependent helicase activity
FD63_RS01450	COG0628	permease
FD63_RS01460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD63_RS01480	COG0628	permease
FD63_RS01495	COG2133	pyrroloquinoline quinone binding
FD63_RS01525	COG0754	glutathionylspermidine amidase activity
FD63_RS01535	COG0714	Associated with various cellular activities
FD63_RS01580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FD63_RS01590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_RS01595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_RS01620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FD63_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS01655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FD63_RS01665	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD63_RS01695	COG0606	chelatase, subunit chli
FD63_RS01700	COG2960	long-chain fatty acid transporting porin activity
FD63_RS01720	COG1166	arginine decarboxylase activity
FD63_RS01725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FD63_RS01730	COG1819	glycosyl
FD63_RS01735	COG2755	lipolytic protein G-D-S-L family
FD63_RS01735	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FD63_RS01740	COG0583	DNA-binding transcription factor activity
FD63_RS01760	COG4221	oxidoreductase activity
FD63_RS01780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FD63_RS01800	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FD63_RS01810	COG2814	Major facilitator Superfamily
FD63_RS01825	COG0739	heme binding
FD63_RS01830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FD63_RS01860	COG1064	alcohol dehydrogenase
FD63_RS01865	COG2234	aminopeptidase activity
FD63_RS01875	COG4942	peptidase
FD63_RS01880	COG0793	Belongs to the peptidase S41A family
FD63_RS01915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FD63_RS01915	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FD63_RS01930	COG1565	acr, cog1565
FD63_RS01930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FD63_RS01935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD63_RS01940	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FD63_RS01970	COG0109	protoheme IX farnesyltransferase activity
FD63_RS01985	COG0358	DNA primase activity
FD63_RS01990	COG1295	ribonuclease BN
FD63_RS02010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FD63_RS02015	COG2308	Evidence 4 Homologs of previously reported genes of
FD63_RS02030	COG2133	pyrroloquinoline quinone binding
FD63_RS02050	COG0531	amino acid
FD63_RS02065	COG4948	Mandelate Racemase Muconate Lactonizing
FD63_RS02075	COG4771	TonB-dependent receptor
FD63_RS02080	COG3023	N-Acetylmuramoyl-L-alanine amidase
FD63_RS02130	COG5383	Protein conserved in bacteria
FD63_RS02145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_RS02150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_RS02155	COG1473	amidohydrolase
FD63_RS02165	COG1652	LysM domain
FD63_RS02220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FD63_RS02225	COG3118	belongs to the thioredoxin family
FD63_RS02235	COG2884	Cell division ATP-binding protein ftsE
FD63_RS02240	COG2177	Part of the ABC transporter FtsEX involved in
FD63_RS02245	COG2201	protein-glutamate methylesterase activity
FD63_RS02250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FD63_RS02255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD63_RS02260	COG2860	membrane
FD63_RS02265	COG1252	NADH dehydrogenase
FD63_RS02270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FD63_RS02280	COG0534	Mate efflux family protein
FD63_RS02285	COG0616	signal peptide processing
FD63_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS02310	COG0009	L-threonylcarbamoyladenylate synthase
FD63_RS02315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FD63_RS02315	COG1754	DNA topoisomerase type I activity
FD63_RS02320	COG1714	RDD family
FD63_RS02335	COG0758	DNA mediated transformation
FD63_RS02340	COG1652	LysM domain
FD63_RS02345	COG0242	peptide deformylase activity
FD63_RS02350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FD63_RS02355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FD63_RS02355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD63_RS02360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FD63_RS02395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FD63_RS02400	COG1247	-acetyltransferase
FD63_RS02410	COG1490	D-aminoacyl-tRNA deacylase activity
FD63_RS02415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FD63_RS02435	COG2963	transposase activity
FD63_RS02450	COG1609	Transcriptional regulator
FD63_RS02460	COG0366	Alpha amylase catalytic
FD63_RS02465	COG0366	Alpha amylase catalytic
FD63_RS02490	COG2801	Transposase and inactivated derivatives
FD63_RS02495	COG2963	transposase activity
FD63_RS02530	COG1309	transcriptional regulator
FD63_RS02560	COG0840	transmembrane signaling receptor activity
FD63_RS02575	COG3546	catalase activity
FD63_RS02580	COG3685	Protein conserved in bacteria
FD63_RS02585	COG3685	Protein conserved in bacteria
FD63_RS02590	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS02600	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FD63_RS02615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FD63_RS02630	COG0028	Belongs to the TPP enzyme family
FD63_RS02635	COG4191	Histidine kinase
FD63_RS02665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FD63_RS02680	COG3645	SOS response
FD63_RS02700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FD63_RS02700	COG1648	precorrin-2 dehydrogenase activity
FD63_RS02710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FD63_RS02710	COG1116	anion transmembrane transporter activity
FD63_RS02715	COG2223	nitrite transmembrane transporter activity
FD63_RS02720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD63_RS02725	COG2146	nitrite reductase [NAD(P)H] activity
FD63_RS02730	COG0243	molybdopterin cofactor binding
FD63_RS02760	COG1640	4-alpha-glucanotransferase
FD63_RS02765	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FD63_RS02785	COG0745	RESPONSE REGULATOR receiver
FD63_RS02810	COG0181	hydroxymethylbilane synthase activity
FD63_RS02825	COG1733	regulation of RNA biosynthetic process
FD63_RS02840	COG1505	serine-type exopeptidase activity
FD63_RS02845	COG0436	Aminotransferase
FD63_RS02860	COG2832	Protein of unknown function (DUF454)
FD63_RS02870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FD63_RS02890	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FD63_RS02915	COG2226	methyltransferase
FD63_RS02920	COG0308	aminopeptidase N
FD63_RS02925	COG0596	Alpha beta hydrolase
FD63_RS02925	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD63_RS02945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD63_RS02950	COG1077	Cell shape determining protein MreB Mrl
FD63_RS02955	COG1792	Involved in formation and maintenance of cell shape
FD63_RS02965	COG0768	penicillin binding
FD63_RS02970	COG0772	Belongs to the SEDS family
FD63_RS02985	COG2951	lytic endotransglycosylase activity
FD63_RS02995	COG1686	Belongs to the peptidase S11 family
FD63_RS03030	COG0321	lipoyl(octanoyl) transferase activity
FD63_RS03035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FD63_RS03060	COG1051	belongs to the nudix hydrolase family
FD63_RS03060	COG1056	cytidyltransferase-related domain
FD63_RS03095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FD63_RS03100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FD63_RS03105	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FD63_RS03110	COG1561	YicC-like family, N-terminal region
FD63_RS03115	COG0194	GDP metabolic process
FD63_RS03120	COG1758	RNA polymerase activity
FD63_RS03125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FD63_RS03140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FD63_RS03150	COG0254	rRNA binding
FD63_RS03155	COG0372	Belongs to the citrate synthase family
FD63_RS03170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FD63_RS03190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FD63_RS03195	COG0667	Aldo Keto reductase
FD63_RS03205	COG4771	TonB-dependent receptor
FD63_RS03225	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FD63_RS03230	COG4181	ATPase activity
FD63_RS03245	COG0642	Histidine kinase
FD63_RS03255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FD63_RS03260	COG0861	Integral membrane protein TerC family
FD63_RS03265	COG1704	LemA family
FD63_RS03295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FD63_RS03300	COG2967	ApaG domain
FD63_RS03305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FD63_RS03315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FD63_RS03320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FD63_RS03325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FD63_RS03335	COG2096	Adenosyltransferase
FD63_RS03345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_RS03350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_RS03390	COG0697	spore germination
FD63_RS03395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FD63_RS03415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FD63_RS03420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FD63_RS03430	COG0583	DNA-binding transcription factor activity
FD63_RS03435	COG3634	alkyl hydroperoxide reductase activity
FD63_RS03460	COG0488	(ABC) transporter
FD63_RS03505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FD63_RS03510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FD63_RS03525	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FD63_RS03535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FD63_RS03545	COG0193	aminoacyl-tRNA hydrolase activity
FD63_RS03550	COG0012	GTP binding
FD63_RS03570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FD63_RS03580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FD63_RS03585	COG0250	Participates in transcription elongation, termination and antitermination
FD63_RS03590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FD63_RS03605	COG0222	ribosome binding
FD63_RS03615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FD63_RS03630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FD63_RS03635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FD63_RS03640	COG0051	transcription antitermination factor activity, RNA binding
FD63_RS03650	COG0088	Forms part of the polypeptide exit tunnel
FD63_RS03655	COG0089	rRNA binding
FD63_RS03660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FD63_RS03685	COG0255	Belongs to the universal ribosomal protein uL29 family
FD63_RS03690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FD63_RS03700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FD63_RS03705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FD63_RS03735	COG1841	ribosomal large subunit assembly
FD63_RS03745	COG0201	protein transport
FD63_RS03770	COG0203	ribosomal protein L17
FD63_RS03775	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FD63_RS03785	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FD63_RS03800	COG1217	gtp-binding protein TYPA
FD63_RS03805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FD63_RS03815	COG0039	L-malate dehydrogenase activity
FD63_RS03830	COG0625	glutathione transferase activity
FD63_RS03875	COG1902	pentaerythritol trinitrate reductase activity
FD63_RS03875	COG0446	pyridine nucleotide-disulphide oxidoreductase
FD63_RS03885	COG0667	Aldo Keto reductase
FD63_RS03900	COG0583	DNA-binding transcription factor activity
FD63_RS03905	COG2885	chlorophyll binding
FD63_RS03925	COG0156	8-amino-7-oxononanoate synthase activity
FD63_RS03930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FD63_RS03935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FD63_RS03940	COG4208	sulfate ABC transporter
FD63_RS03945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FD63_RS03965	COG0588	phosphoglycerate mutase activity
FD63_RS03970	COG0285	dihydrofolate synthase activity
FD63_RS03990	COG2833	Protein of unknown function (DUF455)
FD63_RS03995	COG3291	Pkd domain containing protein
FD63_RS04005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_RS04015	COG0438	transferase activity, transferring glycosyl groups
FD63_RS04020	COG0248	Ppx GppA phosphatase
FD63_RS04025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FD63_RS04040	COG4783	chaperone-mediated protein folding
FD63_RS04055	COG0473	3-isopropylmalate dehydrogenase activity
FD63_RS04090	COG0544	peptidyl-prolyl cis-trans isomerase activity
FD63_RS04100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FD63_RS04140	COG3942	CHAP domain
FD63_RS04140	COG1388	LysM domain
FD63_RS04145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD63_RS04155	COG0328	RNA-DNA hybrid ribonuclease activity
FD63_RS04160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FD63_RS04165	COG0631	protein serine/threonine phosphatase activity
FD63_RS04185	COG0859	PFAM glycosyl transferase family 9
FD63_RS04195	COG1234	tRNA 3'-trailer cleavage
FD63_RS04200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FD63_RS04210	COG0315	cyclic pyranopterin monophosphate synthase activity
FD63_RS04215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FD63_RS04220	COG0314	molybdopterin synthase activity
FD63_RS04250	COG0537	adenosine 5'-monophosphoramidase activity
FD63_RS04270	COG0714	Associated with various cellular activities
FD63_RS04295	COG1399	metal-binding, possibly nucleic acid-binding protein
FD63_RS04305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_RS04310	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FD63_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS04320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD63_RS04330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FD63_RS04335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FD63_RS04340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FD63_RS04360	COG4115	mRNA cleavage
FD63_RS04365	COG2161	toxin-antitoxin pair type II binding
FD63_RS04400	COG0587	DNA-directed DNA polymerase activity
FD63_RS04415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FD63_RS04420	COG0372	Belongs to the citrate synthase family
FD63_RS04435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FD63_RS04460	COG2373	Large extracellular alpha-helical protein
FD63_RS04480	COG4953	penicillin-binding protein 1C
FD63_RS04490	COG0678	peroxiredoxin activity
FD63_RS04510	COG0604	alcohol dehydrogenase
FD63_RS04515	COG0330	HflC and HflK could
FD63_RS04520	COG0330	HflC and HflK could
FD63_RS04530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FD63_RS04555	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FD63_RS04560	COG2801	Transposase and inactivated derivatives
FD63_RS04565	COG2963	transposase activity
FD63_RS04580	COG2801	Transposase and inactivated derivatives
FD63_RS04585	COG2963	transposase activity
FD63_RS04635	COG3459	Glycosyltransferase 36 associated
FD63_RS04645	COG1063	alcohol dehydrogenase
FD63_RS04660	COG4106	trans-aconitate 2-methyltransferase activity
FD63_RS04670	COG0753	catalase activity
FD63_RS04680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD63_RS04680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FD63_RS04700	COG2814	Major facilitator Superfamily
FD63_RS04720	COG2194	sulfuric ester hydrolase activity
FD63_RS04730	COG0745	RESPONSE REGULATOR receiver
FD63_RS04735	COG2205	protein histidine kinase activity
FD63_RS04750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FD63_RS04755	COG2894	cell division
FD63_RS04760	COG0850	regulation of cytokinetic process
FD63_RS04770	COG4585	Histidine kinase
FD63_RS04790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FD63_RS04800	COG1216	Glycosyl transferase, family 2
FD63_RS04805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD63_RS04815	COG1199	ATP-dependent helicase activity
FD63_RS04835	COG0189	ligase activity
FD63_RS04850	COG0835	chemotaxis
FD63_RS04855	COG0840	transmembrane signaling receptor activity
FD63_RS04860	COG0784	Response regulator, receiver
FD63_RS04860	COG0643	Histidine kinase
FD63_RS04860	COG2198	Histidine kinase
FD63_RS04865	COG2201	protein-glutamate methylesterase activity
FD63_RS04880	COG2963	transposase activity
FD63_RS04890	COG1446	asparaginase
FD63_RS04895	COG3142	Participates in the control of copper homeostasis
FD63_RS04935	COG0217	transcriptional regulatory protein
FD63_RS04945	COG0632	four-way junction helicase activity
FD63_RS04950	COG3158	transport of potassium into the cell
FD63_RS04955	COG2255	four-way junction helicase activity
FD63_RS04960	COG0824	Thioesterase
FD63_RS04970	COG0848	biopolymer transport protein
FD63_RS04985	COG2885	chlorophyll binding
FD63_RS04995	COG0602	queuosine metabolic process
FD63_RS05000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FD63_RS05020	COG0514	ATP-dependent DNA helicase (RecQ)
FD63_RS05025	COG0783	Belongs to the Dps family
FD63_RS05030	COG1643	Atp-dependent helicase
FD63_RS05070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FD63_RS05130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FD63_RS05145	COG1946	Acyl-CoA thioesterase
FD63_RS05160	COG0824	Thioesterase
FD63_RS05165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FD63_RS05170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FD63_RS05175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FD63_RS05190	COG0728	peptidoglycan biosynthetic process
FD63_RS05200	COG0196	riboflavin kinase activity
FD63_RS05215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FD63_RS05235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FD63_RS05240	COG1845	cytochrome c oxidase, subunit III
FD63_RS05245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FD63_RS05255	COG0156	8-amino-7-oxononanoate synthase activity
FD63_RS05265	COG3152	Membrane
FD63_RS05290	COG0745	RESPONSE REGULATOR receiver
FD63_RS05320	COG4794	Type iii secretion
FD63_RS05345	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FD63_RS05370	COG1317	bacterial-type flagellum organization
FD63_RS05390	COG2207	Transcriptional regulator
FD63_RS05415	COG0129	dihydroxy-acid dehydratase activity
FD63_RS05435	COG1012	belongs to the aldehyde dehydrogenase family
FD63_RS05440	COG1879	ABC-type sugar transport system periplasmic component
FD63_RS05445	COG1129	ABC transporter
FD63_RS05450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FD63_RS05455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FD63_RS05465	COG1082	Xylose isomerase domain protein TIM barrel
FD63_RS05470	COG0625	glutathione transferase activity
FD63_RS05480	COG0475	glutathione-regulated potassium exporter activity
FD63_RS05505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FD63_RS05510	COG2070	2-Nitropropane dioxygenase
FD63_RS05525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FD63_RS05530	COG0336	Belongs to the RNA methyltransferase TrmD family
FD63_RS05535	COG0335	large ribosomal subunit rRNA binding
FD63_RS05540	COG0534	Mate efflux family protein
FD63_RS05550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FD63_RS05570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FD63_RS05585	COG2855	membrane
FD63_RS05615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD63_RS05620	COG0481	GTPase activity
FD63_RS05625	COG0681	Belongs to the peptidase S26 family
FD63_RS05640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FD63_RS05645	COG1381	Involved in DNA repair and RecF pathway recombination
FD63_RS05650	COG0745	RESPONSE REGULATOR receiver
FD63_RS05660	COG2954	triphosphatase activity
FD63_RS05670	COG1472	Belongs to the glycosyl hydrolase 3 family
FD63_RS05675	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FD63_RS05680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FD63_RS05685	COG1278	Cold shock
FD63_RS05690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FD63_RS05700	COG1201	RNA secondary structure unwinding
FD63_RS05705	COG1793	dna ligase
FD63_RS05705	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FD63_RS05710	COG1793	dna ligase
FD63_RS05710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FD63_RS05740	COG0443	Heat shock 70 kDa protein
FD63_RS05750	COG0183	Belongs to the thiolase family
FD63_RS05780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FD63_RS05780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FD63_RS05780	COG1703	isobutyryl-CoA mutase activity
FD63_RS05835	COG3250	beta-galactosidase activity
FD63_RS05840	COG2186	Transcriptional regulator
FD63_RS05850	COG2198	Histidine kinase
FD63_RS05850	COG0784	Response regulator, receiver
FD63_RS05850	COG2205	protein histidine kinase activity
FD63_RS05875	COG1451	nucleotide metabolic process
FD63_RS05885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FD63_RS05920	COG1077	Cell shape determining protein MreB Mrl
FD63_RS05925	COG1047	Peptidyl-prolyl cis-trans
FD63_RS05930	COG2824	Alkylphosphonate utilization operon protein PhnA
FD63_RS05935	COG1902	pentaerythritol trinitrate reductase activity
FD63_RS05940	COG2814	Major facilitator Superfamily
FD63_RS05970	COG0392	lysyltransferase activity
FD63_RS05970	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FD63_RS05980	COG0251	oxidation-reduction process
FD63_RS06000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FD63_RS06025	COG1595	DNA-templated transcription, initiation
FD63_RS06040	COG2878	Part of a membrane complex involved in electron transport
FD63_RS06060	COG0346	lactoylglutathione lyase activity
FD63_RS06070	COG0833	amino acid
FD63_RS06075	COG2040	homocysteine
FD63_RS06085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FD63_RS06100	COG3118	belongs to the thioredoxin family
FD63_RS06110	COG0495	leucyl-tRNA aminoacylation
FD63_RS06125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FD63_RS06140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FD63_RS06155	COG2968	Membrane
FD63_RS06175	COG0312	modulator of DNA gyrase
FD63_RS06185	COG0312	modulator of DNA gyrase
FD63_RS06285	COG0631	protein serine/threonine phosphatase activity
FD63_RS06290	COG0515	serine threonine protein kinase
FD63_RS06290	COG2815	serine threonine protein kinase
FD63_RS06315	COG1858	cytochrome C peroxidase
FD63_RS06325	COG0142	geranyltranstransferase activity
FD63_RS06330	COG1722	exodeoxyribonuclease VII activity
FD63_RS06335	COG0037	tRNA processing
FD63_RS06345	COG1785	Belongs to the alkaline phosphatase family
FD63_RS06350	COG1301	dicarboxylic acid transport
FD63_RS06360	COG1607	acyl-coa hydrolase
FD63_RS06375	COG0791	NLP P60 protein
FD63_RS06380	COG0791	NLP P60 protein
FD63_RS06385	COG1047	Peptidyl-prolyl cis-trans
FD63_RS06390	COG2311	Membrane
FD63_RS06395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_RS06450	COG3590	peptidase
FD63_RS06465	COG0457	Tetratricopeptide repeat
FD63_RS06470	COG4771	TonB-dependent receptor
FD63_RS06480	COG2963	transposase activity
FD63_RS06485	COG4771	TonB-dependent receptor
FD63_RS06495	COG0489	protein tyrosine kinase activity
FD63_RS06500	COG0717	Belongs to the dCTP deaminase family
FD63_RS06505	COG1714	RDD family
FD63_RS06525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FD63_RS06540	COG0494	nUDIX hydrolase
FD63_RS06545	COG0433	COG0433 Predicted ATPase
FD63_RS06550	COG0741	lytic transglycosylase activity
FD63_RS06555	COG0688	phosphatidylethanolamine metabolic process
FD63_RS06565	COG2890	protein-(glutamine-N5) methyltransferase activity
FD63_RS06580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FD63_RS06630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FD63_RS06650	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS06670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD63_RS06680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FD63_RS06685	COG0649	NAD binding
FD63_RS06690	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FD63_RS06695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FD63_RS06700	COG1034	ATP synthesis coupled electron transport
FD63_RS06720	COG0713	ATP synthesis coupled electron transport
FD63_RS06735	COG1007	ATP synthesis coupled electron transport
FD63_RS06750	COG0195	Participates in both transcription termination and antitermination
FD63_RS06775	COG1185	polyribonucleotide nucleotidyltransferase activity
FD63_RS06780	COG5001	Diguanylate cyclase
FD63_RS06780	COG3300	MHYT domain
FD63_RS06800	COG0840	transmembrane signaling receptor activity
FD63_RS06805	COG0840	transmembrane signaling receptor activity
FD63_RS06810	COG0835	chemotaxis
FD63_RS06850	COG1194	a g-specific adenine glycosylase
FD63_RS06855	COG0552	protein localization to endoplasmic reticulum
FD63_RS06865	COG3938	Belongs to the proline racemase family
FD63_RS06870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_RS06885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FD63_RS06895	COG0006	proline dipeptidase activity
FD63_RS06910	COG0531	amino acid
FD63_RS06945	COG3507	Belongs to the glycosyl hydrolase 43 family
FD63_RS06955	COG4771	TonB-dependent receptor
FD63_RS06980	COG0742	ribosomal rna small subunit methyltransferase
FD63_RS06995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FD63_RS07000	COG0405	Gamma-glutamyltransferase
FD63_RS07005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FD63_RS07010	COG3291	Pkd domain containing protein
FD63_RS07015	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FD63_RS07025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD63_RS07035	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FD63_RS07045	COG1862	Preprotein translocase
FD63_RS07050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FD63_RS07075	COG3706	GGDEF domain
FD63_RS07075	COG2203	Gaf domain
FD63_RS07075	COG5001	Diguanylate cyclase
FD63_RS07075	COG4251	negative regulation of phosphorylation
FD63_RS07080	COG1509	lysine 2,3-aminomutase activity
FD63_RS07090	COG3548	integral membrane protein
FD63_RS07095	COG0402	S-adenosylhomocysteine deaminase activity
FD63_RS07115	COG4677	pectinesterase activity
FD63_RS07135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD63_RS07210	COG2166	iron-sulfur cluster assembly
FD63_RS07225	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FD63_RS07230	COG0137	argininosuccinate synthase activity
FD63_RS07235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FD63_RS07240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FD63_RS07250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FD63_RS07255	COG0165	Argininosuccinate lyase
FD63_RS07275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FD63_RS07295	COG1070	Carbohydrate kinase
FD63_RS07300	COG2115	Belongs to the xylose isomerase family
FD63_RS07305	COG0477	Major facilitator Superfamily
FD63_RS07310	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD63_RS07330	COG0617	tRNA 3'-terminal CCA addition
FD63_RS07340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FD63_RS07355	COG0166	Belongs to the GPI family
FD63_RS07390	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FD63_RS07405	COG0671	phosphoesterase, PA-phosphatase related
FD63_RS07425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FD63_RS07430	COG0167	dihydroorotate dehydrogenase activity
FD63_RS07445	COG1012	belongs to the aldehyde dehydrogenase family
FD63_RS07460	COG0527	aspartate kinase activity
FD63_RS07460	COG0460	homoserine dehydrogenase
FD63_RS07465	COG0083	homoserine kinase activity
FD63_RS07470	COG2951	lytic endotransglycosylase activity
FD63_RS07480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FD63_RS07490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD63_RS07495	COG0124	histidyl-tRNA synthetase
FD63_RS07505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FD63_RS07510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FD63_RS07525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FD63_RS07540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FD63_RS07540	COG0140	phosphoribosyl-ATP diphosphatase activity
FD63_RS07560	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FD63_RS07565	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FD63_RS07570	COG0235	Class ii aldolase
FD63_RS07575	COG0531	amino acid
FD63_RS07580	COG0531	amino acid
FD63_RS07595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FD63_RS07600	COG0277	FAD linked oxidase domain protein
FD63_RS07620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FD63_RS07635	COG1024	Enoyl-CoA hydratase
FD63_RS07665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FD63_RS07675	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FD63_RS07680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FD63_RS07730	COG0438	transferase activity, transferring glycosyl groups
FD63_RS07735	COG0438	transferase activity, transferring glycosyl groups
FD63_RS07745	COG0438	transferase activity, transferring glycosyl groups
FD63_RS07765	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FD63_RS07775	COG1960	acyl-CoA dehydrogenase activity
FD63_RS07820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FD63_RS07825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FD63_RS07825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FD63_RS07830	COG0802	atpase or kinase
FD63_RS07835	COG0860	N-Acetylmuramoyl-L-alanine amidase
FD63_RS07840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FD63_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS07880	COG2081	HI0933 family
FD63_RS07885	COG4681	YaeQ
FD63_RS07890	COG0564	pseudouridine synthase activity
FD63_RS07900	COG0625	glutathione transferase activity
FD63_RS07905	COG0657	acetylesterase activity
FD63_RS07910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FD63_RS07935	COG0513	Belongs to the DEAD box helicase family
FD63_RS07940	COG0488	(ABC) transporter
FD63_RS07950	COG4290	ribonuclease
FD63_RS07955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FD63_RS07965	COG1472	Belongs to the glycosyl hydrolase 3 family
FD63_RS08005	COG1846	Transcriptional regulator
FD63_RS08015	COG0386	Belongs to the glutathione peroxidase family
FD63_RS08040	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FD63_RS08090	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FD63_RS08095	COG0084	hydrolase, TatD family'
FD63_RS08110	COG1960	acyl-CoA dehydrogenase activity
FD63_RS08120	COG0305	Participates in initiation and elongation during chromosome replication
FD63_RS08125	COG0415	Belongs to the DNA photolyase family
FD63_RS08140	COG0583	DNA-binding transcription factor activity
FD63_RS08155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_RS08180	COG1404	Belongs to the peptidase S8 family
FD63_RS08185	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FD63_RS08190	COG2867	negative regulation of translational initiation
FD63_RS08200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_RS08205	COG0735	belongs to the Fur family
FD63_RS08210	COG0497	DNA recombination
FD63_RS08215	COG1420	regulation of RNA biosynthetic process
FD63_RS08220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FD63_RS08225	COG0443	Heat shock 70 kDa protein
FD63_RS08230	COG0484	heat shock protein binding
FD63_RS08235	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FD63_RS08240	COG1605	Chorismate mutase
FD63_RS08240	COG0287	Prephenate dehydrogenase
FD63_RS08250	COG1132	(ABC) transporter
FD63_RS08295	COG2850	peptidyl-arginine hydroxylation
FD63_RS08345	COG1131	(ABC) transporter
FD63_RS08350	COG1725	Transcriptional regulator
FD63_RS08360	COG0386	Belongs to the glutathione peroxidase family
FD63_RS08375	COG2900	Belongs to the SlyX family
FD63_RS08385	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FD63_RS08385	COG2755	lipolytic protein G-D-S-L family
FD63_RS08395	COG0646	methionine synthase
FD63_RS08395	COG1410	methionine synthase
FD63_RS08400	COG0646	methionine synthase
FD63_RS08400	COG1410	methionine synthase
FD63_RS08405	COG2226	methyltransferase
FD63_RS08410	COG1960	acyl-CoA dehydrogenase activity
FD63_RS08425	COG2801	Transposase and inactivated derivatives
FD63_RS08445	COG2963	transposase activity
FD63_RS08450	COG2801	Transposase and inactivated derivatives
FD63_RS08460	COG2963	transposase activity
FD63_RS08500	COG0556	nucleotide-excision repair
FD63_RS08510	COG2963	transposase activity
FD63_RS08515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_RS08520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_RS08530	COG2902	Dehydrogenase
FD63_RS08535	COG2801	Transposase and inactivated derivatives
FD63_RS08540	COG2963	transposase activity
FD63_RS08560	COG1294	oxidase, subunit
FD63_RS08570	COG4988	ABC transporter
FD63_RS08575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FD63_RS08580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD63_RS08625	COG4133	protoheme IX ABC transporter activity
FD63_RS08630	COG0436	Aminotransferase
FD63_RS08655	COG1187	pseudouridine synthase activity
FD63_RS08660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FD63_RS08665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FD63_RS08670	COG2350	Protein conserved in bacteria
FD63_RS08705	COG0395	ABC-type sugar transport system, permease component
FD63_RS08720	COG0129	dihydroxy-acid dehydratase activity
FD63_RS08735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FD63_RS08750	COG2009	succinate dehydrogenase
FD63_RS08755	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FD63_RS08765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FD63_RS08770	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FD63_RS08780	COG4591	ABC-type transport system involved in lipoprotein release permease component
FD63_RS08800	COG0811	peptide transport
FD63_RS08810	COG1132	(ABC) transporter
FD63_RS08815	COG1663	tetraacyldisaccharide 4'-kinase activity
FD63_RS08825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FD63_RS08840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FD63_RS08875	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FD63_RS08880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FD63_RS08890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD63_RS08905	COG2963	transposase activity
FD63_RS08915	COG2963	transposase activity
FD63_RS08925	COG2801	Transposase and inactivated derivatives
FD63_RS08950	COG1132	(ABC) transporter
FD63_RS08975	COG1530	ribonuclease E activity
FD63_RS08990	COG0428	transporter
FD63_RS09005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FD63_RS09005	COG0316	Belongs to the HesB IscA family
FD63_RS09025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_RS09045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FD63_RS09050	COG2957	Belongs to the agmatine deiminase family
FD63_RS09060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FD63_RS09065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FD63_RS09070	COG0539	negative regulation of cytoplasmic translation
FD63_RS09075	COG0776	regulation of translation
FD63_RS09085	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FD63_RS09090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FD63_RS09100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FD63_RS09105	COG0183	Belongs to the thiolase family
FD63_RS09110	COG1024	Enoyl-CoA hydratase
FD63_RS09110	COG1250	3-hydroxyacyl-CoA dehydrogenase
FD63_RS09125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FD63_RS09135	COG1426	Protein conserved in bacteria
FD63_RS09145	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_RS09155	COG0746	molybdenum cofactor guanylyltransferase activity
FD63_RS09165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FD63_RS09170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FD63_RS09170	COG0475	glutathione-regulated potassium exporter activity
FD63_RS09185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FD63_RS09195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FD63_RS09195	COG0519	Catalyzes the synthesis of GMP from XMP
FD63_RS09200	COG1501	Belongs to the glycosyl hydrolase 31 family
FD63_RS09205	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FD63_RS09215	COG1914	H( )-stimulated, divalent metal cation uptake system
FD63_RS09230	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FD63_RS09235	COG0668	transmembrane transport
FD63_RS09245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FD63_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS09265	COG1183	phosphatidylcholine synthase activity
FD63_RS09275	COG3243	poly(R)-hydroxyalkanoic acid synthase
FD63_RS09295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_RS09295	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FD63_RS09305	COG0784	Response regulator, receiver
FD63_RS09305	COG4191	Histidine kinase
FD63_RS09310	COG2183	response to ionizing radiation
FD63_RS09315	COG0784	Response regulator, receiver
FD63_RS09315	COG2205	protein histidine kinase activity
FD63_RS09350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_RS09380	COG1649	PFAM Uncharacterised BCR, COG1649
FD63_RS09395	COG1304	FMN binding
FD63_RS09405	COG0346	lactoylglutathione lyase activity
FD63_RS09450	COG1024	Enoyl-CoA hydratase
FD63_RS09455	COG1024	Enoyl-CoA hydratase
FD63_RS09465	COG1024	Enoyl-CoA hydratase
FD63_RS09480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FD63_RS09485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FD63_RS09505	COG2963	transposase activity
FD63_RS09510	COG2801	Transposase and inactivated derivatives
FD63_RS09520	COG1074	ATP-dependent DNA helicase activity
FD63_RS09555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FD63_RS09560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FD63_RS09570	COG0505	Belongs to the CarA family
FD63_RS09575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FD63_RS09580	COG2258	MOSC domain
FD63_RS09585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FD63_RS09590	COG2963	transposase activity
FD63_RS09595	COG2801	Transposase and inactivated derivatives
FD63_RS09605	COG0438	transferase activity, transferring glycosyl groups
FD63_RS09610	COG0438	transferase activity, transferring glycosyl groups
FD63_RS09630	COG4106	trans-aconitate 2-methyltransferase activity
FD63_RS09650	COG2244	polysaccharide biosynthetic process
FD63_RS09680	COG3038	cytochrome b561
FD63_RS09700	COG1595	DNA-templated transcription, initiation
FD63_RS09755	COG0038	chloride channel
FD63_RS09760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FD63_RS09780	COG1674	ftsk spoiiie
FD63_RS09785	COG0492	ferredoxin-NADP+ reductase activity
FD63_RS09795	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FD63_RS09805	COG0542	response to heat
FD63_RS09825	COG0482	sulfurtransferase activity
FD63_RS09830	COG2915	High frequency lysogenization protein hflD homolog
FD63_RS09890	COG0784	Response regulator, receiver
FD63_RS09890	COG0835	chemotaxis
FD63_RS09900	COG1558	bacterial-type flagellum-dependent cell motility
FD63_RS09910	COG1749	Flagellar hook protein flgE
FD63_RS09925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FD63_RS09940	COG1256	bacterial-type flagellum assembly
FD63_RS09940	COG4786	Flagellar basal body rod
FD63_RS09940	COG4786	Flagellar basal body rod
FD63_RS09940	COG1256	bacterial-type flagellum assembly
FD63_RS09950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FD63_RS09955	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FD63_RS09975	COG2197	response regulator
FD63_RS09985	COG2201	protein-glutamate methylesterase activity
FD63_RS10005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_RS10015	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS10045	COG1677	Flagellar hook-basal body complex protein FliE
FD63_RS10095	COG3190	flagellar
FD63_RS10105	COG1987	bacterial-type flagellum assembly
FD63_RS10110	COG1684	flagellar biosynthetic protein fliR
FD63_RS10155	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FD63_RS10160	COG2198	Histidine kinase
FD63_RS10160	COG0784	Response regulator, receiver
FD63_RS10160	COG0643	Histidine kinase
FD63_RS10165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FD63_RS10175	COG1192	Involved in chromosome partitioning
FD63_RS10180	COG0835	chemotaxis
FD63_RS10190	COG0745	RESPONSE REGULATOR receiver
FD63_RS10205	COG0840	transmembrane signaling receptor activity
FD63_RS10210	COG0840	transmembrane signaling receptor activity
FD63_RS10215	COG0840	transmembrane signaling receptor activity
FD63_RS10220	COG0840	transmembrane signaling receptor activity
FD63_RS10230	COG0840	transmembrane signaling receptor activity
FD63_RS10235	COG0840	transmembrane signaling receptor activity
FD63_RS10240	COG0840	transmembrane signaling receptor activity
FD63_RS10245	COG0840	transmembrane signaling receptor activity
FD63_RS10255	COG0840	transmembrane signaling receptor activity
FD63_RS10265	COG0835	chemotaxis
FD63_RS10275	COG0840	transmembrane signaling receptor activity
FD63_RS10285	COG0840	transmembrane signaling receptor activity
FD63_RS10340	COG0318	PFAM AMP-dependent synthetase and ligase
FD63_RS10345	COG2205	protein histidine kinase activity
FD63_RS10345	COG0784	Response regulator, receiver
FD63_RS10345	COG2198	Histidine kinase
FD63_RS10360	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FD63_RS10365	COG3279	Response regulator of the LytR AlgR family
FD63_RS10380	COG0800	Aldolase
FD63_RS10395	COG3734	2-keto-3-deoxy-galactonokinase
FD63_RS10400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FD63_RS10410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FD63_RS10420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FD63_RS10425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FD63_RS10450	COG0351	phosphomethylpyrimidine kinase
FD63_RS10450	COG0352	thiamine-phosphate diphosphorylase activity
FD63_RS10470	COG0583	DNA-binding transcription factor activity
FD63_RS10475	COG1741	Belongs to the pirin family
FD63_RS10505	COG2137	regulation of response to DNA damage stimulus
FD63_RS10510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FD63_RS10515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FD63_RS10520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD63_RS10525	COG1546	Belongs to the CinA family
FD63_RS10530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FD63_RS10540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FD63_RS10545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FD63_RS10550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FD63_RS10555	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FD63_RS10560	COG1534	Rna-binding protein
FD63_RS10575	COG1238	metal cluster binding
FD63_RS10585	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FD63_RS10600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FD63_RS10605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FD63_RS10650	COG0306	phosphate transporter
FD63_RS10660	COG1253	flavin adenine dinucleotide binding
FD63_RS10670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD63_RS10705	COG0069	glutamate synthase activity
FD63_RS10710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FD63_RS10720	COG1609	Transcriptional regulator
FD63_RS10725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD63_RS10725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD63_RS10730	COG1105	Belongs to the carbohydrate kinase PfkB family
FD63_RS10735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD63_RS10735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FD63_RS10770	COG1136	(ABC) transporter
FD63_RS10770	COG0577	efflux transmembrane transporter activity
FD63_RS10840	COG0583	DNA-binding transcription factor activity
FD63_RS10865	COG1605	Chorismate mutase
FD63_RS10865	COG0077	Prephenate dehydratase
FD63_RS10870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FD63_RS10875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FD63_RS10915	COG4221	oxidoreductase activity
FD63_RS10930	COG1228	amidohydrolase
FD63_RS10945	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FD63_RS10960	COG1309	transcriptional regulator
FD63_RS10980	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FD63_RS10990	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FD63_RS10995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FD63_RS11000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FD63_RS11035	COG0316	Belongs to the HesB IscA family
FD63_RS11060	COG2197	response regulator
FD63_RS11105	COG0288	reversible hydration of carbon dioxide
FD63_RS11120	COG3844	kynureninase activity
FD63_RS11130	COG2925	Exonuclease
FD63_RS11175	COG2963	transposase activity
FD63_RS11180	COG2801	Transposase and inactivated derivatives
FD63_RS11220	COG3275	phosphorelay sensor kinase activity
FD63_RS11225	COG1611	Belongs to the LOG family
FD63_RS11235	COG2095	MarC family integral membrane protein
FD63_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS11245	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FD63_RS11285	COG2969	positive regulation of protein catabolic process
FD63_RS11290	COG0625	glutathione transferase activity
FD63_RS11295	COG2857	Cytochrome c1
FD63_RS11300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FD63_RS11305	COG0723	plastoquinol--plastocyanin reductase activity
FD63_RS11325	COG1702	phosphate starvation-inducible protein PhoH
FD63_RS11340	COG4535	Mg2 and Co2 transporter CorC
FD63_RS11350	COG0598	Magnesium transport protein CorA
FD63_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
FD63_RS11365	COG1177	transmembrane transport
FD63_RS11370	COG1176	ABC-type spermidine putrescine transport system, permease component I
FD63_RS11375	COG3842	ATPase activity
FD63_RS11410	COG0174	glutamine synthetase
FD63_RS11415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FD63_RS11420	COG0174	glutamine synthetase
FD63_RS11425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_RS11435	COG0477	Major facilitator Superfamily
FD63_RS11450	COG0243	molybdopterin cofactor binding
FD63_RS11460	COG2223	nitrite transmembrane transporter activity
FD63_RS11480	COG1012	belongs to the aldehyde dehydrogenase family
FD63_RS11485	COG1917	Cupin 2, conserved barrel domain protein
FD63_RS11485	COG1396	sequence-specific DNA binding
FD63_RS11490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FD63_RS11495	COG0686	Belongs to the AlaDH PNT family
FD63_RS11515	COG2733	membrane
FD63_RS11520	COG2205	protein histidine kinase activity
FD63_RS11520	COG0784	Response regulator, receiver
FD63_RS11520	COG5002	protein histidine kinase activity
FD63_RS11580	COG1024	Enoyl-CoA hydratase
FD63_RS11590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FD63_RS11595	COG0659	secondary active sulfate transmembrane transporter activity
FD63_RS11615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD63_RS11620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FD63_RS11630	COG0581	inorganic phosphate transmembrane transporter activity
FD63_RS11640	COG0704	Plays a role in the regulation of phosphate uptake
FD63_RS11660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FD63_RS11680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD63_RS11690	COG0557	exoribonuclease II activity
FD63_RS11725	COG2814	Major facilitator Superfamily
FD63_RS11730	COG1566	PFAM secretion protein HlyD family protein
FD63_RS11770	COG0367	asparagine synthase
FD63_RS11780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FD63_RS11785	COG1393	Belongs to the ArsC family
FD63_RS11800	COG0024	Methionine aminopeptidase
FD63_RS11840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FD63_RS11850	COG0528	UMP kinase activity
FD63_RS11860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FD63_RS11865	COG0575	Belongs to the CDS family
FD63_RS11870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FD63_RS11875	COG0750	zinc metalloprotease
FD63_RS11885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_RS11895	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_RS11900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FD63_RS11925	COG1981	membrane
FD63_RS11990	COG2801	Transposase and inactivated derivatives
FD63_RS11995	COG2963	transposase activity
FD63_RS12005	COG1132	(ABC) transporter
FD63_RS12025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FD63_RS12050	COG1187	pseudouridine synthase activity
FD63_RS12150	COG2080	2 iron, 2 sulfur cluster binding
FD63_RS12155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FD63_RS12160	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FD63_RS12200	COG0735	belongs to the Fur family
FD63_RS12235	COG2205	protein histidine kinase activity
FD63_RS12240	COG0745	RESPONSE REGULATOR receiver
FD63_RS12245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FD63_RS12265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FD63_RS12275	COG2198	Histidine kinase
FD63_RS12275	COG0643	Histidine kinase
FD63_RS12280	COG0840	transmembrane signaling receptor activity
FD63_RS12285	COG0840	transmembrane signaling receptor activity
FD63_RS12290	COG0840	transmembrane signaling receptor activity
FD63_RS12295	COG0835	chemotaxis
FD63_RS12320	COG2801	Transposase and inactivated derivatives
FD63_RS12330	COG2211	Major facilitator Superfamily
FD63_RS12360	COG1741	Belongs to the pirin family
FD63_RS12365	COG1966	Carbon starvation protein
FD63_RS12370	COG2879	small protein
FD63_RS12380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FD63_RS12400	COG0823	Involved in the tonB-independent uptake of proteins
FD63_RS12400	COG1506	peptidase
FD63_RS12405	COG1297	OPT oligopeptide transporter protein
FD63_RS12410	COG3104	oligopeptide transport
FD63_RS12430	COG0629	single-stranded DNA binding
FD63_RS12435	COG0142	geranyltranstransferase activity
FD63_RS12460	COG0527	aspartate kinase activity
FD63_RS12465	COG0384	phenazine biosynthesis protein PhzF
FD63_RS12475	COG1764	response to oxidative stress
FD63_RS12490	COG0739	heme binding
FD63_RS12505	COG0693	protein deglycase activity
FD63_RS12520	COG0719	Fe-S assembly protein
FD63_RS12525	COG0396	ATPase activity
FD63_RS12530	COG0719	Fe-S assembly protein
FD63_RS12535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FD63_RS12545	COG2146	nitrite reductase [NAD(P)H] activity
FD63_RS12550	COG4774	siderophore transport
FD63_RS12575	COG1477	protein flavinylation
FD63_RS12580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD63_RS12600	COG1555	photosystem II stabilization
FD63_RS12615	COG3178	'Phosphotransferase
FD63_RS12620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FD63_RS12630	COG0628	permease
FD63_RS12655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FD63_RS12695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FD63_RS12710	COG1137	ATPase activity
FD63_RS12725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD63_RS12735	COG1660	Displays ATPase and GTPase activities
FD63_RS12745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FD63_RS12750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FD63_RS12755	COG2239	Acts as a magnesium transporter
FD63_RS12780	COG1113	amino acid transport
FD63_RS12790	COG0840	transmembrane signaling receptor activity
FD63_RS12815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FD63_RS12830	COG0519	Catalyzes the synthesis of GMP from XMP
FD63_RS12885	COG0259	pyridoxamine-phosphate oxidase activity
FD63_RS12890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FD63_RS12905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FD63_RS12910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FD63_RS12920	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FD63_RS12925	COG2814	Major facilitator Superfamily
FD63_RS12945	COG3038	cytochrome b561
FD63_RS12960	COG1760	l-serine dehydratase
FD63_RS12975	COG0460	homoserine dehydrogenase
FD63_RS12975	COG0527	aspartate kinase activity
FD63_RS12980	COG0626	cystathionine gamma-synthase activity
FD63_RS12985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FD63_RS12995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FD63_RS13000	COG1272	protein, Hemolysin III
FD63_RS13005	COG2982	Protein involved in outer membrane biogenesis
FD63_RS13010	COG0517	IMP dehydrogenase activity
FD63_RS13015	COG0463	Glycosyl transferase, family 2
FD63_RS13020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FD63_RS13025	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FD63_RS13040	COG2963	transposase activity
FD63_RS13045	COG2801	Transposase and inactivated derivatives
FD63_RS13070	COG1304	FMN binding
FD63_RS13080	COG1657	PFAM Prenyltransferase squalene oxidase
FD63_RS13085	COG0142	geranyltranstransferase activity
FD63_RS13090	COG2124	cytochrome p450
FD63_RS13095	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS13100	COG1141	Ferredoxin
FD63_RS13105	COG2124	cytochrome p450
FD63_RS13110	COG2124	cytochrome p450
FD63_RS13170	COG0330	HflC and HflK could
FD63_RS13175	COG1742	UPF0060 membrane protein
FD63_RS13180	COG3956	TIGRFAM MazG family protein
FD63_RS13185	COG1218	3'(2'),5'-bisphosphate nucleotidase
FD63_RS13190	COG0494	nUDIX hydrolase
FD63_RS13200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FD63_RS13210	COG0837	glucose binding
FD63_RS13225	COG1388	LysM domain
FD63_RS13225	COG3858	chitin binding
FD63_RS13230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FD63_RS13240	COG1472	Belongs to the glycosyl hydrolase 3 family
FD63_RS13260	COG3537	Alpha-1,2-mannosidase
FD63_RS13300	COG2963	transposase activity
FD63_RS13415	COG2963	transposase activity
FD63_RS13520	COG3209	COG3209 Rhs family protein
FD63_RS13525	COG3209	COG3209 Rhs family protein
FD63_RS13605	COG0521	Mo-molybdopterin cofactor biosynthetic process
FD63_RS13630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD63_RS13635	COG1295	ribonuclease BN
FD63_RS13655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FD63_RS13660	COG1404	Belongs to the peptidase S8 family
FD63_RS13665	COG1404	Belongs to the peptidase S8 family
FD63_RS13670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FD63_RS13710	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FD63_RS13730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_RS13730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_RS13765	COG2963	transposase activity
FD63_RS13770	COG2801	Transposase and inactivated derivatives
FD63_RS13775	COG2963	transposase activity
FD63_RS13780	COG2801	Transposase and inactivated derivatives
FD63_RS13810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FD63_RS13810	COG4651	solute:proton antiporter activity
FD63_RS13825	COG4772	TonB-dependent receptor
FD63_RS13835	COG4264	IucA IucC family
FD63_RS13840	COG2814	Major facilitator Superfamily
FD63_RS13845	COG4264	IucA IucC family
FD63_RS13850	COG0019	diaminopimelate decarboxylase activity
FD63_RS13875	COG0542	response to heat
FD63_RS13925	COG3387	PFAM Glycoside hydrolase 15-related
FD63_RS13935	COG4993	Dehydrogenase
FD63_RS13950	COG0564	pseudouridine synthase activity
FD63_RS13955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FD63_RS13965	COG1125	glycine betaine transport
FD63_RS13970	COG1174	glycine betaine transport
FD63_RS13985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FD63_RS13995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FD63_RS13995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FD63_RS14055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FD63_RS14070	COG0745	RESPONSE REGULATOR receiver
FD63_RS14080	COG0189	ligase activity
FD63_RS14090	COG3511	phospholipase C
FD63_RS14140	COG2022	thiamine diphosphate biosynthetic process
FD63_RS14150	COG0471	metal ion transport
FD63_RS14150	COG3273	potassium ion transport
FD63_RS14165	COG0179	Fumarylacetoacetate (FAA) hydrolase
FD63_RS14180	COG1609	Transcriptional regulator
FD63_RS14195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FD63_RS14205	COG1115	amino acid carrier protein
FD63_RS14225	COG0840	transmembrane signaling receptor activity
FD63_RS14230	COG2895	sulfate adenylyltransferase (ATP) activity
FD63_RS14230	COG0529	Catalyzes the synthesis of activated sulfate
FD63_RS14240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FD63_RS14245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FD63_RS14250	COG0175	sulfate reduction
FD63_RS14280	COG1393	Belongs to the ArsC family
FD63_RS14285	COG0784	Response regulator, receiver
FD63_RS14285	COG2205	protein histidine kinase activity
FD63_RS14285	COG2198	Histidine kinase
FD63_RS14315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FD63_RS14355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FD63_RS14360	COG3588	fructose-bisphosphate aldolase
FD63_RS14365	COG0469	pyruvate kinase activity
FD63_RS14410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FD63_RS14415	COG3047	cAMP biosynthetic process
FD63_RS14435	COG0640	Transcriptional regulator
FD63_RS14445	COG0725	ABC transporter, periplasmic molybdate-binding protein
FD63_RS14450	COG4149	molybdate abc transporter
FD63_RS14455	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FD63_RS14480	COG1376	ErfK ybiS ycfS ynhG family protein
FD63_RS14485	COG0739	heme binding
FD63_RS14510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FD63_RS14515	COG1301	dicarboxylic acid transport
FD63_RS14545	COG0714	Associated with various cellular activities
FD63_RS14590	COG0006	proline dipeptidase activity
FD63_RS14595	COG0006	proline dipeptidase activity
FD63_RS14600	COG3079	Belongs to the UPF0149 family
FD63_RS14620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FD63_RS14630	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FD63_RS14645	COG1773	rubredoxin
FD63_RS14660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FD63_RS14675	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FD63_RS14685	COG2010	Cytochrome c
FD63_RS14695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FD63_RS14705	COG1940	carbohydrate kinase activity
FD63_RS14720	COG0671	phosphoesterase, PA-phosphatase related
FD63_RS14730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FD63_RS14755	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FD63_RS14765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FD63_RS14785	COG0840	transmembrane signaling receptor activity
FD63_RS14790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FD63_RS14810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FD63_RS14820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FD63_RS14825	COG0066	3-isopropylmalate dehydratase activity
FD63_RS14830	COG0473	3-isopropylmalate dehydrogenase activity
FD63_RS14835	COG3706	GGDEF domain
FD63_RS14845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FD63_RS14850	COG1538	Outer membrane efflux protein
FD63_RS14855	COG1519	Transferase
FD63_RS14860	COG1560	Kdo2-lipid A biosynthetic process
FD63_RS14905	COG0281	malic enzyme
FD63_RS14905	COG0280	phosphate acetyltransferase
FD63_RS14910	COG1301	dicarboxylic acid transport
FD63_RS14920	COG4191	Histidine kinase
FD63_RS14940	COG0642	Histidine kinase
FD63_RS14955	COG2851	Citrate transporter
FD63_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS14970	COG2211	Major facilitator Superfamily
FD63_RS14995	COG1162	GTPase activity
FD63_RS15000	COG0436	Aminotransferase
FD63_RS15025	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FD63_RS15040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FD63_RS15045	COG0804	urea catabolic process
FD63_RS15080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FD63_RS15090	COG3791	Glutathione-dependent formaldehyde-activating
FD63_RS15095	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FD63_RS15110	COG2205	protein histidine kinase activity
FD63_RS15180	COG0617	tRNA 3'-terminal CCA addition
FD63_RS15190	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FD63_RS15195	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FD63_RS15200	COG1609	Transcriptional regulator
FD63_RS15205	COG0738	Major facilitator superfamily
FD63_RS15210	COG2188	Transcriptional regulator
FD63_RS15225	COG3250	beta-galactosidase activity
FD63_RS15255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FD63_RS15265	COG4191	Histidine kinase
FD63_RS15270	COG0784	Response regulator, receiver
FD63_RS15275	COG2202	Pas domain
FD63_RS15275	COG2205	protein histidine kinase activity
FD63_RS15285	COG2823	Periplasmic or secreted lipoprotein
FD63_RS15290	COG0673	inositol 2-dehydrogenase activity
FD63_RS15295	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FD63_RS15305	COG1090	epimerase
FD63_RS15325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FD63_RS15365	COG2226	methyltransferase
FD63_RS15390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FD63_RS15400	COG0494	nUDIX hydrolase
FD63_RS15415	COG0739	heme binding
FD63_RS15425	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FD63_RS15430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FD63_RS15440	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FD63_RS15445	COG1181	Belongs to the D-alanine--D-alanine ligase family
FD63_RS15470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FD63_RS15485	COG3116	cell division
FD63_RS15490	COG0275	rRNA processing
FD63_RS15495	COG2001	Belongs to the MraZ family
FD63_RS15520	COG0792	nuclease activity
FD63_RS15525	COG1988	membrane-bound metal-dependent
FD63_RS15530	COG0277	FAD linked oxidase domain protein
FD63_RS15535	COG0745	RESPONSE REGULATOR receiver
FD63_RS15540	COG2205	protein histidine kinase activity
FD63_RS15550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FD63_RS15555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FD63_RS15580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FD63_RS15585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FD63_RS15590	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FD63_RS15605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD63_RS15605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FD63_RS15615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FD63_RS15645	COG0477	Major facilitator Superfamily
FD63_RS15650	COG0488	(ABC) transporter
FD63_RS15655	COG0242	peptide deformylase activity
FD63_RS15675	COG1215	transferase activity, transferring glycosyl groups
FD63_RS15685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FD63_RS15690	COG0457	Tetratricopeptide repeat
FD63_RS15740	COG2188	Transcriptional regulator
FD63_RS15750	COG1450	Type ii and iii secretion system protein
FD63_RS15765	COG3166	PFAM Fimbrial assembly family protein
FD63_RS15770	COG3156	type II secretion system protein K
FD63_RS15775	COG4795	General secretion pathway protein
FD63_RS15780	COG2165	general secretion pathway protein
FD63_RS15785	COG4970	Tfp pilus assembly protein FimT
FD63_RS15790	COG2165	general secretion pathway protein
FD63_RS15795	COG1459	type II secretion system
FD63_RS15800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FD63_RS15805	COG1404	Belongs to the peptidase S8 family
FD63_RS15810	COG5295	Hep Hag repeat protein
FD63_RS15820	COG0840	transmembrane signaling receptor activity
FD63_RS15825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FD63_RS15825	COG0047	phosphoribosylformylglycinamidine synthase activity
FD63_RS15830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FD63_RS15835	COG4974	Belongs to the 'phage' integrase family
FD63_RS15860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FD63_RS15865	COG2927	DNA polymerase III (CHI subunit)
FD63_RS15900	COG1183	phosphatidylcholine synthase activity
FD63_RS15910	COG0442	prolyl-tRNA aminoacylation
FD63_RS15925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FD63_RS15930	COG1127	ABC transporter
FD63_RS15935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FD63_RS15935	COG3218	ABC-type transport auxiliary lipoprotein component
FD63_RS15965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FD63_RS15970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FD63_RS15975	COG0662	Cupin 2, conserved barrel domain protein
FD63_RS15975	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FD63_RS16000	COG2086	electron transfer activity
FD63_RS16015	COG0546	phosphoglycolate phosphatase activity
FD63_RS16015	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FD63_RS16020	COG0277	FAD linked oxidase domain protein
FD63_RS16025	COG0300	oxidoreductase activity
FD63_RS16045	COG0493	'glutamate synthase
FD63_RS16065	COG0438	transferase activity, transferring glycosyl groups
FD63_RS16065	COG1216	Glycosyl transferase, family 2
FD63_RS16085	COG0438	transferase activity, transferring glycosyl groups
FD63_RS16085	COG1216	Glycosyl transferase, family 2
FD63_RS16090	COG1216	Glycosyl transferase, family 2
FD63_RS16090	COG0438	transferase activity, transferring glycosyl groups
FD63_RS16095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FD63_RS16110	COG0626	cystathionine gamma-synthase activity
FD63_RS16140	COG0625	glutathione transferase activity
FD63_RS16150	COG0513	Belongs to the DEAD box helicase family
FD63_RS16155	COG0720	synthase
FD63_RS16165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FD63_RS16170	COG1956	GAF domain-containing protein
FD63_RS16180	COG4206	TonB-dependent receptor
FD63_RS16185	COG0546	phosphoglycolate phosphatase activity
FD63_RS16190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FD63_RS16210	COG0339	signal peptide processing
FD63_RS16225	COG2217	Heavy metal translocating P-type atpase
FD63_RS16240	COG2132	Multicopper oxidase
FD63_RS16255	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FD63_RS16265	COG1136	(ABC) transporter
FD63_RS16270	COG1136	(ABC) transporter
FD63_RS16270	COG0577	efflux transmembrane transporter activity
FD63_RS16275	COG1136	(ABC) transporter
FD63_RS16275	COG0577	efflux transmembrane transporter activity
FD63_RS16280	COG0577	efflux transmembrane transporter activity
FD63_RS16280	COG1136	(ABC) transporter
FD63_RS16300	COG4191	Histidine kinase
FD63_RS16310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FD63_RS16325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FD63_RS16340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FD63_RS16350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FD63_RS16360	COG0356	it plays a direct role in the translocation of protons across the membrane
FD63_RS16375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FD63_RS16380	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD63_RS16415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FD63_RS16420	COG0697	spore germination
FD63_RS16425	COG1666	GTP binding
FD63_RS16435	COG1187	pseudouridine synthase activity
FD63_RS16460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FD63_RS16460	COG2205	protein histidine kinase activity
FD63_RS16480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FD63_RS16545	COG0842	Transport permease protein
FD63_RS16550	COG1131	(ABC) transporter
FD63_RS16555	COG0025	NhaP-type Na H and K H
FD63_RS16565	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FD63_RS16570	COG1573	uracil-dna glycosylase
FD63_RS16580	COG3384	dioxygenase
FD63_RS16605	COG0667	Aldo Keto reductase
FD63_RS16615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FD63_RS16620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD63_RS16640	COG3706	GGDEF domain
FD63_RS16650	COG5001	Diguanylate cyclase
FD63_RS16680	COG4106	trans-aconitate 2-methyltransferase activity
FD63_RS16690	COG2076	Multidrug Resistance protein
FD63_RS16700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FD63_RS16720	COG3279	Response regulator of the LytR AlgR family
FD63_RS16725	COG3275	phosphorelay sensor kinase activity
FD63_RS16750	COG0531	amino acid
FD63_RS16760	COG5297	Belongs to the glycosyl hydrolase family 6
FD63_RS16760	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FD63_RS16775	COG0741	lytic transglycosylase activity
FD63_RS16795	COG2207	Transcriptional regulator
FD63_RS16805	COG0598	Magnesium transport protein CorA
FD63_RS16810	COG1113	amino acid transport
FD63_RS16815	COG0697	spore germination
FD63_RS16825	COG0583	DNA-binding transcription factor activity
FD63_RS16840	COG5520	Belongs to the glycosyl hydrolase 30 family
FD63_RS16915	COG0840	transmembrane signaling receptor activity
FD63_RS16930	COG2353	YceI-like domain
FD63_RS16955	COG0584	glycerophosphoryl diester phosphodiesterase
FD63_RS16965	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FD63_RS16985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FD63_RS17000	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FD63_RS17010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FD63_RS17015	COG0459	protein refolding
FD63_RS17025	COG1324	tolerance protein
FD63_RS17035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FD63_RS17045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FD63_RS17050	COG0511	ligase activity, forming carbon-carbon bonds
FD63_RS17055	COG0439	Biotin carboxylase
FD63_RS17075	COG2264	protein methyltransferase activity
FD63_RS17095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FD63_RS17105	COG4589	Belongs to the CDS family
FD63_RS17125	COG2267	carboxylic ester hydrolase activity
FD63_RS17130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FD63_RS17135	COG0138	bifunctional purine biosynthesis protein purh
FD63_RS17140	COG0151	Belongs to the GarS family
FD63_RS17145	COG1289	transmembrane transporter activity
FD63_RS17150	COG2814	Major facilitator Superfamily
FD63_RS17190	COG2816	NAD+ diphosphatase activity
FD63_RS17230	COG2906	2 iron, 2 sulfur cluster binding
FD63_RS17260	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FD63_RS17275	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FD63_RS17280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FD63_RS17285	COG0730	response to heat
FD63_RS17300	COG0134	indole-3-glycerol-phosphate synthase activity
FD63_RS17305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FD63_RS17325	COG1597	lipid kinase activity
FD63_RS17340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FD63_RS17355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FD63_RS17360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FD63_RS17360	COG2111	Na H antiporter
FD63_RS17365	COG1006	Multisubunit Na H antiporter MnhC subunit
FD63_RS17370	COG0651	ATP synthesis coupled electron transport
FD63_RS17375	COG1863	multisubunit Na H antiporter MnhE subunit
FD63_RS17380	COG2212	antiporter activity
FD63_RS17385	COG1320	monovalent cation:proton antiporter activity
FD63_RS17390	COG0530	calcium, potassium:sodium antiporter activity
FD63_RS17405	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FD63_RS17425	COG3104	oligopeptide transport
FD63_RS17430	COG3483	tryptophan 2,3-dioxygenase activity
FD63_RS17445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FD63_RS17460	COG0508	dehydrogenase complex catalyzes the overall conversion of
FD63_RS17470	COG2963	transposase activity
FD63_RS17490	COG0513	Belongs to the DEAD box helicase family
FD63_RS17505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FD63_RS17515	COG2354	Protein conserved in bacteria
FD63_RS17530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FD63_RS17535	COG1196	nuclear chromosome segregation
FD63_RS17535	COG3264	Mechanosensitive ion channel
FD63_RS17540	COG0604	alcohol dehydrogenase
FD63_RS17540	COG3321	synthase
FD63_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS17560	COG1595	DNA-templated transcription, initiation
FD63_RS17575	COG1802	Transcriptional regulator
FD63_RS17610	COG3052	prosthetic group binding
FD63_RS17620	COG1414	Transcriptional regulator
FD63_RS17625	COG0738	Major facilitator superfamily
FD63_RS17630	COG3254	rhamnose metabolic process
FD63_RS17635	COG4948	Mandelate Racemase Muconate Lactonizing
FD63_RS17640	COG0179	Fumarylacetoacetate (FAA) hydrolase
FD63_RS17645	COG1028	Short-chain dehydrogenase reductase Sdr
FD63_RS17680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FD63_RS17695	COG4807	Protein conserved in bacteria
FD63_RS17720	COG4773	Receptor
FD63_RS17735	COG1506	peptidase
FD63_RS17735	COG0823	Involved in the tonB-independent uptake of proteins
FD63_RS17780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FD63_RS17800	COG0628	permease
FD63_RS17805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FD63_RS17810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FD63_RS17815	COG0753	catalase activity
FD63_RS17825	COG2197	response regulator
FD63_RS17840	COG1136	(ABC) transporter
FD63_RS17845	COG0577	efflux transmembrane transporter activity
FD63_RS17865	COG0697	spore germination
FD63_RS17880	COG0180	Tryptophanyl-tRNA synthetase
FD63_RS17915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FD63_RS17920	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FD63_RS17920	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FD63_RS17930	COG3228	Belongs to the MtfA family
FD63_RS17960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FD63_RS17985	COG2084	Dehydrogenase
FD63_RS17990	COG1902	pentaerythritol trinitrate reductase activity
FD63_RS18015	COG1404	Belongs to the peptidase S8 family
FD63_RS18020	COG2814	Major facilitator Superfamily
FD63_RS18025	COG0583	DNA-binding transcription factor activity
FD63_RS18035	COG2801	Transposase and inactivated derivatives
FD63_RS18040	COG2963	transposase activity
FD63_RS18060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FD63_RS18065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FD63_RS18075	COG1764	response to oxidative stress
FD63_RS18080	COG1846	Transcriptional regulator
FD63_RS18085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FD63_RS18095	COG0697	spore germination
FD63_RS18105	COG0523	cobalamin synthesis protein
FD63_RS18115	COG1742	UPF0060 membrane protein
FD63_RS18120	COG3245	cytochrome
FD63_RS18130	COG1960	acyl-CoA dehydrogenase activity
FD63_RS18135	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FD63_RS18165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FD63_RS18170	COG3387	PFAM Glycoside hydrolase 15-related
FD63_RS18175	COG0745	RESPONSE REGULATOR receiver
FD63_RS18190	COG1404	Belongs to the peptidase S8 family
FD63_RS18200	COG3100	YcgL domain-containing protein
FD63_RS18205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FD63_RS18215	COG0463	Glycosyl transferase, family 2
FD63_RS18250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FD63_RS18265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FD63_RS18290	COG1294	oxidase, subunit
FD63_RS18295	COG1271	oxidase subunit
FD63_RS18310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FD63_RS18315	COG0408	coproporphyrinogen oxidase activity
FD63_RS18325	COG2323	membrane
FD63_RS18330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_RS18330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FD63_RS18345	COG0589	response to stress
FD63_RS18365	COG0210	DNA helicase
FD63_RS18415	COG0463	Glycosyl transferase, family 2
FD63_RS18425	COG1475	DNA binding
FD63_RS18430	COG1192	Involved in chromosome partitioning
FD63_RS18435	COG0357	Ribosomal RNA small subunit methyltransferase G
FD63_RS18450	COG2091	lysine biosynthetic process via aminoadipic acid
FD63_RS18480	COG0477	Major facilitator Superfamily
FD63_RS18500	COG1971	Probably functions as a manganese efflux pump
FD63_RS18505	COG2205	protein histidine kinase activity
FD63_RS18515	COG3459	Glycosyltransferase 36 associated
FD63_RS18520	COG2211	Major facilitator Superfamily
FD63_RS18525	COG3265	gluconokinase activity
FD63_RS18545	COG2911	Protein conserved in bacteria
FD63_RS18550	COG0729	surface antigen
FD63_RS18570	COG3132	Protein of unknown function, DUF480
FD63_RS18590	COG2963	transposase activity
FD63_RS18595	COG2963	transposase activity
FD63_RS18600	COG2801	Transposase and inactivated derivatives
FD63_RS18625	COG0284	orotidine-5'-phosphate decarboxylase activity
FD63_RS18650	COG2937	Belongs to the GPAT DAPAT family
FD63_RS18675	COG2211	Major facilitator Superfamily
FD63_RS18685	COG3693	PFAM glycoside hydrolase, family 10
FD63_RS18690	COG1904	glucuronate isomerase
FD63_RS18705	COG3386	PFAM SMP-30 Gluconolaconase
FD63_RS18715	COG2963	transposase activity
FD63_RS18725	COG3046	protein related to deoxyribodipyrimidine photolyase
FD63_RS18735	COG0246	Mannitol dehydrogenase
FD63_RS18740	COG1472	Belongs to the glycosyl hydrolase 3 family
FD63_RS18750	COG4948	Mandelate Racemase Muconate Lactonizing
FD63_RS18760	COG3661	Belongs to the glycosyl hydrolase 67 family
FD63_RS18770	COG2115	Belongs to the xylose isomerase family
FD63_RS18780	COG0037	tRNA processing
FD63_RS18805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FD63_RS18815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FD63_RS18825	COG0805	protein transport
FD63_RS18835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FD63_RS18835	COG0519	Catalyzes the synthesis of GMP from XMP
FD63_RS18840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FD63_RS18860	COG0210	DNA helicase
FD63_RS18865	COG1435	thymidine kinase activity
FD63_RS18875	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FD63_RS18885	COG0457	Tetratricopeptide repeat
FD63_RS18885	COG0515	serine threonine protein kinase
FD63_RS18900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FD63_RS18915	COG1119	ATPase activity
FD63_RS18930	COG0706	membrane insertase activity
FD63_RS18935	COG0594	ribonuclease P activity
FD63_RS18995	COG2201	protein-glutamate methylesterase activity
FD63_RS19045	COG0840	transmembrane signaling receptor activity