locus-tag	class	description
BJD12_RS00010	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BJD12_RS00035	COG1472	Belongs to the glycosyl hydrolase 3 family
BJD12_RS00050	COG5001	Diguanylate cyclase
BJD12_RS00050	COG4251	negative regulation of phosphorylation
BJD12_RS00050	COG3706	GGDEF domain
BJD12_RS00050	COG2203	Gaf domain
BJD12_RS00055	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BJD12_RS00060	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BJD12_RS00070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BJD12_RS00075	COG0671	phosphoesterase, PA-phosphatase related
BJD12_RS00085	COG1794	racemase activity, acting on amino acids and derivatives
BJD12_RS00090	COG0697	spore germination
BJD12_RS00095	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BJD12_RS00115	COG1012	belongs to the aldehyde dehydrogenase family
BJD12_RS00145	COG2963	transposase activity
BJD12_RS00150	COG2801	Transposase and inactivated derivatives
BJD12_RS00205	COG2003	Belongs to the UPF0758 family
BJD12_RS00360	COG2814	Major facilitator Superfamily
BJD12_RS00435	COG0840	transmembrane signaling receptor activity
BJD12_RS00450	COG1215	transferase activity, transferring glycosyl groups
BJD12_RS00455	COG0726	polysaccharide deacetylase
BJD12_RS00455	COG1649	PFAM Uncharacterised BCR, COG1649
BJD12_RS00505	COG2801	Transposase and inactivated derivatives
BJD12_RS00510	COG2963	transposase activity
BJD12_RS00525	COG0527	aspartate kinase activity
BJD12_RS00525	COG0460	homoserine dehydrogenase
BJD12_RS00540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BJD12_RS00550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BJD12_RS00555	COG0124	histidyl-tRNA synthetase
BJD12_RS00570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BJD12_RS00575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJD12_RS00580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BJD12_RS00580	COG0131	Imidazoleglycerol-phosphate dehydratase
BJD12_RS00585	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BJD12_RS00590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BJD12_RS00595	COG0107	imidazoleglycerol-phosphate synthase activity
BJD12_RS00600	COG0140	phosphoribosyl-ATP diphosphatase activity
BJD12_RS00600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BJD12_RS00620	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BJD12_RS00625	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BJD12_RS00640	COG0531	amino acid
BJD12_RS00645	COG0531	amino acid
BJD12_RS00655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BJD12_RS00660	COG0277	FAD linked oxidase domain protein
BJD12_RS00680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BJD12_RS00700	COG1024	Enoyl-CoA hydratase
BJD12_RS00725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BJD12_RS00730	COG2258	MOSC domain
BJD12_RS00740	COG0505	Belongs to the CarA family
BJD12_RS00750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BJD12_RS00755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BJD12_RS00765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BJD12_RS00780	COG3279	Response regulator of the LytR AlgR family
BJD12_RS00785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BJD12_RS00790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BJD12_RS00805	COG0784	Response regulator, receiver
BJD12_RS00805	COG2198	Histidine kinase
BJD12_RS00805	COG2205	protein histidine kinase activity
BJD12_RS00810	COG1024	Enoyl-CoA hydratase
BJD12_RS00815	COG0318	PFAM AMP-dependent synthetase and ligase
BJD12_RS00845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BJD12_RS00870	COG0840	transmembrane signaling receptor activity
BJD12_RS00880	COG0835	chemotaxis
BJD12_RS00895	COG0840	transmembrane signaling receptor activity
BJD12_RS00905	COG0840	transmembrane signaling receptor activity
BJD12_RS00910	COG0840	transmembrane signaling receptor activity
BJD12_RS00915	COG0840	transmembrane signaling receptor activity
BJD12_RS00930	COG0840	transmembrane signaling receptor activity
BJD12_RS00935	COG0840	transmembrane signaling receptor activity
BJD12_RS00955	COG0745	RESPONSE REGULATOR receiver
BJD12_RS00965	COG0835	chemotaxis
BJD12_RS00970	COG1192	Involved in chromosome partitioning
BJD12_RS00980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BJD12_RS01035	COG2963	transposase activity
BJD12_RS01040	COG2801	Transposase and inactivated derivatives
BJD12_RS01055	COG0643	Histidine kinase
BJD12_RS01055	COG0784	Response regulator, receiver
BJD12_RS01055	COG2198	Histidine kinase
BJD12_RS01105	COG3300	MHYT domain
BJD12_RS01105	COG5001	Diguanylate cyclase
BJD12_RS01180	COG1677	Flagellar hook-basal body complex protein FliE
BJD12_RS01230	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS01255	COG2201	protein-glutamate methylesterase activity
BJD12_RS01285	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BJD12_RS01290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BJD12_RS01295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BJD12_RS01305	COG3951	Flagellar rod assembly protein muramidase FlgJ
BJD12_RS01305	COG1705	Flagellar rod assembly protein muramidase FlgJ
BJD12_RS01335	COG4787	bacterial-type flagellum-dependent cell motility
BJD12_RS01345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BJD12_RS01350	COG1558	bacterial-type flagellum-dependent cell motility
BJD12_RS01355	COG1815	bacterial-type flagellum-dependent cell motility
BJD12_RS01360	COG0784	Response regulator, receiver
BJD12_RS01360	COG0835	chemotaxis
BJD12_RS01380	COG4191	Histidine kinase
BJD12_RS01420	COG0482	sulfurtransferase activity
BJD12_RS01435	COG0542	response to heat
BJD12_RS01460	COG0492	ferredoxin-NADP+ reductase activity
BJD12_RS01465	COG1674	ftsk spoiiie
BJD12_RS01480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BJD12_RS01485	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BJD12_RS01490	COG0183	Belongs to the thiolase family
BJD12_RS01495	COG1024	Enoyl-CoA hydratase
BJD12_RS01495	COG1250	3-hydroxyacyl-CoA dehydrogenase
BJD12_RS01520	COG1426	Protein conserved in bacteria
BJD12_RS01530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BJD12_RS01535	COG1160	GTP binding
BJD12_RS01545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BJD12_RS01560	COG0708	Exodeoxyribonuclease III
BJD12_RS01575	COG0746	molybdenum cofactor guanylyltransferase activity
BJD12_RS01585	COG1648	precorrin-2 dehydrogenase activity
BJD12_RS01585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJD12_RS01595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BJD12_RS01605	COG2223	nitrite transmembrane transporter activity
BJD12_RS01610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BJD12_RS01615	COG2146	nitrite reductase [NAD(P)H] activity
BJD12_RS01620	COG0243	molybdopterin cofactor binding
BJD12_RS01635	COG3685	Protein conserved in bacteria
BJD12_RS01645	COG5001	Diguanylate cyclase
BJD12_RS01715	COG1238	metal cluster binding
BJD12_RS01725	COG3226	Transcriptional regulator
BJD12_RS01735	COG2223	nitrite transmembrane transporter activity
BJD12_RS01740	COG4221	oxidoreductase activity
BJD12_RS01765	COG0363	glucosamine-6-phosphate deaminase activity
BJD12_RS01785	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BJD12_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS01805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BJD12_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS01820	COG0583	DNA-binding transcription factor activity
BJD12_RS01835	COG2369	cell adhesion
BJD12_RS01920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BJD12_RS02030	COG2154	pterin-4-alpha-carbinolamine dehydratase
BJD12_RS02040	COG0428	transporter
BJD12_RS02045	COG3064	Membrane
BJD12_RS02055	COG1530	ribonuclease E activity
BJD12_RS02065	COG1054	Belongs to the UPF0176 family
BJD12_RS02085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BJD12_RS02115	COG0322	excinuclease ABC activity
BJD12_RS02125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BJD12_RS02130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BJD12_RS02135	COG1663	tetraacyldisaccharide 4'-kinase activity
BJD12_RS02140	COG1132	(ABC) transporter
BJD12_RS02150	COG0811	peptide transport
BJD12_RS02175	COG4591	ABC-type transport system involved in lipoprotein release permease component
BJD12_RS02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BJD12_RS02190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BJD12_RS02205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BJD12_RS02220	COG0354	folic acid binding
BJD12_RS02230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BJD12_RS02235	COG0837	glucose binding
BJD12_RS02240	COG0363	glucosamine-6-phosphate deaminase activity
BJD12_RS02245	COG0129	dihydroxy-acid dehydratase activity
BJD12_RS02250	COG0800	Aldolase
BJD12_RS02315	COG2205	protein histidine kinase activity
BJD12_RS02315	COG5002	protein histidine kinase activity
BJD12_RS02315	COG0784	Response regulator, receiver
BJD12_RS02320	COG2183	response to ionizing radiation
BJD12_RS02345	COG3243	poly(R)-hydroxyalkanoic acid synthase
BJD12_RS02355	COG1183	phosphatidylcholine synthase activity
BJD12_RS02360	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS02385	COG0668	transmembrane transport
BJD12_RS02390	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BJD12_RS02405	COG1914	H( )-stimulated, divalent metal cation uptake system
BJD12_RS02420	COG2814	Major facilitator Superfamily
BJD12_RS02435	COG1335	isochorismatase
BJD12_RS02445	COG4585	Histidine kinase
BJD12_RS02450	COG2197	response regulator
BJD12_RS02475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BJD12_RS02485	COG0475	glutathione-regulated potassium exporter activity
BJD12_RS02485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BJD12_RS02490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BJD12_RS02500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BJD12_RS02505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BJD12_RS02515	COG0776	regulation of translation
BJD12_RS02520	COG0539	negative regulation of cytoplasmic translation
BJD12_RS02525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BJD12_RS02540	COG2957	Belongs to the agmatine deiminase family
BJD12_RS02545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BJD12_RS02570	COG0395	ABC-type sugar transport system, permease component
BJD12_RS02575	COG1175	transmembrane transport
BJD12_RS02580	COG1653	transport
BJD12_RS02605	COG2350	Protein conserved in bacteria
BJD12_RS02610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BJD12_RS02615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BJD12_RS02620	COG1187	pseudouridine synthase activity
BJD12_RS02635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BJD12_RS02645	COG0436	Aminotransferase
BJD12_RS02650	COG4133	protoheme IX ABC transporter activity
BJD12_RS02715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BJD12_RS02725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BJD12_RS02730	COG4988	ABC transporter
BJD12_RS02740	COG1294	oxidase, subunit
BJD12_RS02765	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BJD12_RS02785	COG0165	Argininosuccinate lyase
BJD12_RS02800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BJD12_RS02805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJD12_RS02815	COG0137	argininosuccinate synthase activity
BJD12_RS02825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BJD12_RS02835	COG0215	cysteine-tRNA ligase activity
BJD12_RS02840	COG2166	iron-sulfur cluster assembly
BJD12_RS02860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BJD12_RS02880	COG4302	ethanolamine ammonia-lyase activity
BJD12_RS02900	COG4677	pectinesterase activity
BJD12_RS02920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BJD12_RS02925	COG0402	S-adenosylhomocysteine deaminase activity
BJD12_RS02940	COG1509	lysine 2,3-aminomutase activity
BJD12_RS02945	COG5001	Diguanylate cyclase
BJD12_RS02945	COG3300	MHYT domain
BJD12_RS02960	COG0483	inositol monophosphate 1-phosphatase activity
BJD12_RS02965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BJD12_RS02985	COG0488	(ABC) transporter
BJD12_RS02990	COG0513	Belongs to the DEAD box helicase family
BJD12_RS03000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BJD12_RS03005	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BJD12_RS03015	COG0625	glutathione transferase activity
BJD12_RS03025	COG1671	Belongs to the UPF0178 family
BJD12_RS03030	COG4681	YaeQ
BJD12_RS03035	COG2081	HI0933 family
BJD12_RS03045	COG0501	Belongs to the peptidase M48B family
BJD12_RS03050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BJD12_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS03075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BJD12_RS03080	COG0860	N-Acetylmuramoyl-L-alanine amidase
BJD12_RS03090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BJD12_RS03090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BJD12_RS03095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BJD12_RS03110	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BJD12_RS03145	COG0582	viral genome integration into host DNA
BJD12_RS03180	COG0835	chemotaxis
BJD12_RS03185	COG0840	transmembrane signaling receptor activity
BJD12_RS03195	COG1201	RNA secondary structure unwinding
BJD12_RS03210	COG2969	positive regulation of protein catabolic process
BJD12_RS03215	COG0625	glutathione transferase activity
BJD12_RS03220	COG2857	Cytochrome c1
BJD12_RS03225	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BJD12_RS03230	COG0723	plastoquinol--plastocyanin reductase activity
BJD12_RS03235	COG0741	lytic transglycosylase activity
BJD12_RS03255	COG1702	phosphate starvation-inducible protein PhoH
BJD12_RS03265	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BJD12_RS03275	COG4535	Mg2 and Co2 transporter CorC
BJD12_RS03290	COG1012	belongs to the aldehyde dehydrogenase family
BJD12_RS03300	COG1177	transmembrane transport
BJD12_RS03305	COG1176	ABC-type spermidine putrescine transport system, permease component I
BJD12_RS03310	COG3842	ATPase activity
BJD12_RS03330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BJD12_RS03350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BJD12_RS03355	COG0174	glutamine synthetase
BJD12_RS03360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BJD12_RS03375	COG2703	oxygen carrier activity
BJD12_RS03380	COG0477	Major facilitator Superfamily
BJD12_RS03395	COG0243	molybdopterin cofactor binding
BJD12_RS03400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BJD12_RS03405	COG2223	nitrite transmembrane transporter activity
BJD12_RS03410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BJD12_RS03420	COG2733	membrane
BJD12_RS03425	COG5002	protein histidine kinase activity
BJD12_RS03425	COG2205	protein histidine kinase activity
BJD12_RS03425	COG0784	Response regulator, receiver
BJD12_RS03435	COG0477	Major facilitator Superfamily
BJD12_RS03450	COG2902	Dehydrogenase
BJD12_RS03460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BJD12_RS03465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BJD12_RS03480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BJD12_RS03480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD12_RS03485	COG1105	Belongs to the carbohydrate kinase PfkB family
BJD12_RS03490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJD12_RS03490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BJD12_RS03570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BJD12_RS03580	COG1862	Preprotein translocase
BJD12_RS03585	COG0343	queuine tRNA-ribosyltransferase activity
BJD12_RS03590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BJD12_RS03630	COG3291	Pkd domain containing protein
BJD12_RS03640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BJD12_RS03655	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BJD12_RS03660	COG0742	ribosomal rna small subunit methyltransferase
BJD12_RS03685	COG4206	TonB-dependent receptor
BJD12_RS03715	COG0531	amino acid
BJD12_RS03730	COG0006	proline dipeptidase activity
BJD12_RS03740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BJD12_RS03755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BJD12_RS03760	COG3938	Belongs to the proline racemase family
BJD12_RS03770	COG0552	protein localization to endoplasmic reticulum
BJD12_RS03795	COG4191	Histidine kinase
BJD12_RS03795	COG0784	Response regulator, receiver
BJD12_RS03840	COG1960	acyl-CoA dehydrogenase activity
BJD12_RS03850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BJD12_RS03870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BJD12_RS03880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BJD12_RS03910	COG0438	transferase activity, transferring glycosyl groups
BJD12_RS03920	COG0438	transferase activity, transferring glycosyl groups
BJD12_RS03925	COG0438	transferase activity, transferring glycosyl groups
BJD12_RS03975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJD12_RS03975	COG0072	phenylalanine-tRNA ligase activity
BJD12_RS03980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BJD12_RS03995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BJD12_RS04000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BJD12_RS04025	COG1082	Xylose isomerase domain protein TIM barrel
BJD12_RS04040	COG0366	Alpha amylase catalytic
BJD12_RS04045	COG2801	Transposase and inactivated derivatives
BJD12_RS04095	COG3702	type iv secretory pathway
BJD12_RS04115	COG2948	multi-organism process
BJD12_RS04135	COG3505	Type IV secretory pathway VirD4
BJD12_RS04150	COG0556	nucleotide-excision repair
BJD12_RS04200	COG3275	phosphorelay sensor kinase activity
BJD12_RS04205	COG1611	Belongs to the LOG family
BJD12_RS04215	COG2095	MarC family integral membrane protein
BJD12_RS04225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BJD12_RS04260	COG1185	polyribonucleotide nucleotidyltransferase activity
BJD12_RS04265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BJD12_RS04270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BJD12_RS04275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BJD12_RS04280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BJD12_RS04285	COG0195	Participates in both transcription termination and antitermination
BJD12_RS04290	COG0779	Required for maturation of 30S ribosomal subunits
BJD12_RS04300	COG1007	ATP synthesis coupled electron transport
BJD12_RS04340	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BJD12_RS04345	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BJD12_RS04350	COG0649	NAD binding
BJD12_RS04355	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BJD12_RS04365	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BJD12_RS04380	COG0149	triose-phosphate isomerase activity
BJD12_RS04385	COG4221	oxidoreductase activity
BJD12_RS04420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BJD12_RS04425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BJD12_RS04440	COG0133	tryptophan synthase activity
BJD12_RS04455	COG0101	tRNA pseudouridine synthase activity
BJD12_RS04470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BJD12_RS04475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BJD12_RS04480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BJD12_RS04490	COG2890	protein-(glutamine-N5) methyltransferase activity
BJD12_RS04500	COG0688	phosphatidylethanolamine metabolic process
BJD12_RS04510	COG0741	lytic transglycosylase activity
BJD12_RS04515	COG0433	COG0433 Predicted ATPase
BJD12_RS04525	COG0494	nUDIX hydrolase
BJD12_RS04555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BJD12_RS04585	COG0717	Belongs to the dCTP deaminase family
BJD12_RS04595	COG0489	protein tyrosine kinase activity
BJD12_RS04615	COG3590	peptidase
BJD12_RS04620	COG3590	peptidase
BJD12_RS04640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BJD12_RS04645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BJD12_RS04650	COG2311	Membrane
BJD12_RS04655	COG1047	Peptidyl-prolyl cis-trans
BJD12_RS04660	COG0791	NLP P60 protein
BJD12_RS04665	COG0791	NLP P60 protein
BJD12_RS04710	COG2226	methyltransferase
BJD12_RS04715	COG1301	dicarboxylic acid transport
BJD12_RS04720	COG1785	Belongs to the alkaline phosphatase family
BJD12_RS04725	COG0037	tRNA processing
BJD12_RS04730	COG1722	exodeoxyribonuclease VII activity
BJD12_RS04735	COG0142	geranyltranstransferase activity
BJD12_RS04745	COG4104	PAAR repeat-containing protein
BJD12_RS04755	COG0312	modulator of DNA gyrase
BJD12_RS04760	COG3028	Belongs to the UPF0307 family
BJD12_RS04765	COG0312	modulator of DNA gyrase
BJD12_RS04785	COG0424	maF-like protein
BJD12_RS04790	COG2968	Membrane
BJD12_RS04820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BJD12_RS04835	COG0495	leucyl-tRNA aminoacylation
BJD12_RS04845	COG3118	belongs to the thioredoxin family
BJD12_RS04855	COG2155	Conserved Protein
BJD12_RS04910	COG1132	(ABC) transporter
BJD12_RS04920	COG0475	glutathione-regulated potassium exporter activity
BJD12_RS04930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BJD12_RS04955	COG1187	pseudouridine synthase activity
BJD12_RS04960	COG5001	Diguanylate cyclase
BJD12_RS04960	COG5002	protein histidine kinase activity
BJD12_RS05010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BJD12_RS05090	COG0667	Aldo Keto reductase
BJD12_RS05095	COG2814	Major facilitator Superfamily
BJD12_RS05100	COG0583	DNA-binding transcription factor activity
BJD12_RS05110	COG2207	Transcriptional regulator
BJD12_RS05125	COG0667	Aldo Keto reductase
BJD12_RS05130	COG1309	transcriptional regulator
BJD12_RS05155	COG0735	belongs to the Fur family
BJD12_RS05185	COG4452	Inner membrane protein CreD
BJD12_RS05190	COG2205	protein histidine kinase activity
BJD12_RS05195	COG0745	RESPONSE REGULATOR receiver
BJD12_RS05200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BJD12_RS05220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BJD12_RS05230	COG0643	Histidine kinase
BJD12_RS05230	COG2198	Histidine kinase
BJD12_RS05240	COG0840	transmembrane signaling receptor activity
BJD12_RS05245	COG0835	chemotaxis
BJD12_RS05255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BJD12_RS05270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BJD12_RS05275	COG3590	peptidase
BJD12_RS05285	COG0588	phosphoglycerate mutase activity
BJD12_RS05290	COG1515	deoxyribonuclease V activity
BJD12_RS05305	COG1741	Belongs to the pirin family
BJD12_RS05320	COG1741	Belongs to the pirin family
BJD12_RS05325	COG1966	Carbon starvation protein
BJD12_RS05330	COG2879	small protein
BJD12_RS05370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BJD12_RS05375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BJD12_RS05385	COG2080	2 iron, 2 sulfur cluster binding
BJD12_RS05390	COG3321	synthase
BJD12_RS05390	COG0604	alcohol dehydrogenase
BJD12_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS05400	COG0629	single-stranded DNA binding
BJD12_RS05405	COG0142	geranyltranstransferase activity
BJD12_RS05415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BJD12_RS05430	COG0527	aspartate kinase activity
BJD12_RS05435	COG0384	phenazine biosynthesis protein PhzF
BJD12_RS05440	COG0384	phenazine biosynthesis protein PhzF
BJD12_RS05450	COG1764	response to oxidative stress
BJD12_RS05460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BJD12_RS05465	COG1678	Uncharacterized ACR, COG1678
BJD12_RS05470	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BJD12_RS05475	COG0519	Catalyzes the synthesis of GMP from XMP
BJD12_RS05505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BJD12_RS05520	COG4942	peptidase
BJD12_RS05540	COG0693	protein deglycase activity
BJD12_RS05550	COG1959	2 iron, 2 sulfur cluster binding
BJD12_RS05555	COG0719	Fe-S assembly protein
BJD12_RS05560	COG0396	ATPase activity
BJD12_RS05565	COG0719	Fe-S assembly protein
BJD12_RS05570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BJD12_RS05575	COG0456	acetyltransferase
BJD12_RS05585	COG4774	siderophore transport
BJD12_RS05620	COG1477	protein flavinylation
BJD12_RS05635	COG1555	photosystem II stabilization
BJD12_RS05640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJD12_RS05655	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BJD12_RS05665	COG0628	permease
BJD12_RS05675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BJD12_RS05690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BJD12_RS05735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BJD12_RS05745	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BJD12_RS05750	COG1137	ATPase activity
BJD12_RS05765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD12_RS05775	COG1660	Displays ATPase and GTPase activities
BJD12_RS05785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BJD12_RS05790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BJD12_RS05795	COG2239	Acts as a magnesium transporter
BJD12_RS05805	COG1294	oxidase, subunit
BJD12_RS05810	COG1271	oxidase subunit
BJD12_RS05815	COG1113	amino acid transport
BJD12_RS05835	COG2197	response regulator
BJD12_RS05840	COG0531	amino acid
BJD12_RS05900	COG2814	Major facilitator Superfamily
BJD12_RS05910	COG0754	glutathionylspermidine amidase activity
BJD12_RS05935	COG1842	Phage shock protein A
BJD12_RS05955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BJD12_RS05960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BJD12_RS05970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BJD12_RS05975	COG2814	Major facilitator Superfamily
BJD12_RS05995	COG2353	YceI-like domain
BJD12_RS06010	COG1278	Cold shock
BJD12_RS06025	COG1760	l-serine dehydratase
BJD12_RS06035	COG0460	homoserine dehydrogenase
BJD12_RS06035	COG0527	aspartate kinase activity
BJD12_RS06040	COG0626	cystathionine gamma-synthase activity
BJD12_RS06045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BJD12_RS06050	COG0739	heme binding
BJD12_RS06055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BJD12_RS06060	COG1272	protein, Hemolysin III
BJD12_RS06065	COG2982	Protein involved in outer membrane biogenesis
BJD12_RS06075	COG0517	IMP dehydrogenase activity
BJD12_RS06075	COG0516	GMP reductase activity
BJD12_RS06080	COG0463	Glycosyl transferase, family 2
BJD12_RS06085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BJD12_RS06090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BJD12_RS06100	COG4771	TonB-dependent receptor
BJD12_RS06105	COG1309	transcriptional regulator
BJD12_RS06115	COG1960	acyl-CoA dehydrogenase activity
BJD12_RS06145	COG0509	glycine decarboxylation via glycine cleavage system
BJD12_RS06150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BJD12_RS06160	COG0330	HflC and HflK could
BJD12_RS06170	COG3956	TIGRFAM MazG family protein
BJD12_RS06175	COG1218	3'(2'),5'-bisphosphate nucleotidase
BJD12_RS06180	COG0494	nUDIX hydrolase
BJD12_RS06190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BJD12_RS06195	COG0837	glucose binding
BJD12_RS06210	COG1388	LysM domain
BJD12_RS06210	COG3858	chitin binding
BJD12_RS06230	COG1472	Belongs to the glycosyl hydrolase 3 family
BJD12_RS06240	COG3537	Alpha-1,2-mannosidase
BJD12_RS06280	COG3142	Participates in the control of copper homeostasis
BJD12_RS06285	COG1446	asparaginase
BJD12_RS06290	COG2304	oxidoreductase activity
BJD12_RS06320	COG0643	Histidine kinase
BJD12_RS06320	COG2198	Histidine kinase
BJD12_RS06320	COG0784	Response regulator, receiver
BJD12_RS06325	COG0840	transmembrane signaling receptor activity
BJD12_RS06330	COG0835	chemotaxis
BJD12_RS06345	COG0189	ligase activity
BJD12_RS06355	COG1397	ADP-ribosylglycohydrolase
BJD12_RS06365	COG1199	ATP-dependent helicase activity
BJD12_RS06375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BJD12_RS06380	COG1216	Glycosyl transferase, family 2
BJD12_RS06390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BJD12_RS06400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BJD12_RS06405	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BJD12_RS06410	COG0535	radical SAM domain protein
BJD12_RS06430	COG0837	glucose binding
BJD12_RS06440	COG1643	Atp-dependent helicase
BJD12_RS06445	COG0783	Belongs to the Dps family
BJD12_RS06450	COG0514	ATP-dependent DNA helicase (RecQ)
BJD12_RS06470	COG1187	pseudouridine synthase activity
BJD12_RS06480	COG0840	transmembrane signaling receptor activity
BJD12_RS06505	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BJD12_RS06510	COG0602	queuosine metabolic process
BJD12_RS06520	COG2885	chlorophyll binding
BJD12_RS06525	COG0823	Involved in the tonB-independent uptake of proteins
BJD12_RS06535	COG0848	biopolymer transport protein
BJD12_RS06545	COG0824	Thioesterase
BJD12_RS06550	COG2255	four-way junction helicase activity
BJD12_RS06565	COG0632	four-way junction helicase activity
BJD12_RS06570	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BJD12_RS06590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BJD12_RS06610	COG0477	Major facilitator Superfamily
BJD12_RS06630	COG0640	Transcriptional regulator
BJD12_RS06635	COG0730	response to heat
BJD12_RS06655	COG2755	lipolytic protein G-D-S-L family
BJD12_RS06655	COG0657	acetylesterase activity
BJD12_RS06670	COG2951	lytic endotransglycosylase activity
BJD12_RS06680	COG0488	(ABC) transporter
BJD12_RS06715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BJD12_RS06715	COG4651	solute:proton antiporter activity
BJD12_RS06725	COG4772	TonB-dependent receptor
BJD12_RS06735	COG4264	IucA IucC family
BJD12_RS06745	COG4264	IucA IucC family
BJD12_RS06750	COG0019	diaminopimelate decarboxylase activity
BJD12_RS06770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BJD12_RS06780	COG1492	cobalamin metabolic process
BJD12_RS06790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BJD12_RS06810	COG4206	TonB-dependent receptor
BJD12_RS06820	COG0542	response to heat
BJD12_RS06870	COG3387	PFAM Glycoside hydrolase 15-related
BJD12_RS06885	COG0840	transmembrane signaling receptor activity
BJD12_RS06905	COG0564	pseudouridine synthase activity
BJD12_RS06910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BJD12_RS06920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BJD12_RS06920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BJD12_RS06935	COG0045	succinate-CoA ligase (ADP-forming) activity
BJD12_RS06970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BJD12_RS06975	COG0237	dephospho-CoA kinase activity
BJD12_RS06985	COG0745	RESPONSE REGULATOR receiver
BJD12_RS06995	COG0189	ligase activity
BJD12_RS07200	COG3273	potassium ion transport
BJD12_RS07200	COG0471	metal ion transport
BJD12_RS07220	COG1970	mechanosensitive ion channel activity
BJD12_RS07230	COG1609	Transcriptional regulator
BJD12_RS07240	COG5297	Belongs to the glycosyl hydrolase family 6
BJD12_RS07250	COG3250	beta-galactosidase activity
BJD12_RS07255	COG4948	Mandelate Racemase Muconate Lactonizing
BJD12_RS07260	COG2272	Belongs to the type-B carboxylesterase lipase family
BJD12_RS07265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BJD12_RS07270	COG1115	amino acid carrier protein
BJD12_RS07285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BJD12_RS07290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BJD12_RS07295	COG2895	sulfate adenylyltransferase (ATP) activity
BJD12_RS07295	COG0529	Catalyzes the synthesis of activated sulfate
BJD12_RS07305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BJD12_RS07310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BJD12_RS07315	COG0175	sulfate reduction
BJD12_RS07335	COG2198	Histidine kinase
BJD12_RS07335	COG0784	Response regulator, receiver
BJD12_RS07335	COG2205	protein histidine kinase activity
BJD12_RS07350	COG1648	precorrin-2 dehydrogenase activity
BJD12_RS07350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BJD12_RS07365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BJD12_RS07370	COG3588	fructose-bisphosphate aldolase
BJD12_RS07380	COG0469	pyruvate kinase activity
BJD12_RS07410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BJD12_RS07430	COG3047	cAMP biosynthetic process
BJD12_RS07440	COG3453	Protein conserved in bacteria
BJD12_RS07440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJD12_RS07445	COG0725	ABC transporter, periplasmic molybdate-binding protein
BJD12_RS07450	COG4149	molybdate abc transporter
BJD12_RS07490	COG1376	ErfK ybiS ycfS ynhG family protein
BJD12_RS07495	COG0739	heme binding
BJD12_RS07505	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS07510	COG0583	DNA-binding transcription factor activity
BJD12_RS07515	COG4773	Receptor
BJD12_RS07520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BJD12_RS07525	COG1301	dicarboxylic acid transport
BJD12_RS07535	COG2304	oxidoreductase activity
BJD12_RS07555	COG0714	Associated with various cellular activities
BJD12_RS07585	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BJD12_RS07615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BJD12_RS07630	COG2721	sulfolactate sulfo-lyase activity
BJD12_RS07645	COG2271	Major facilitator Superfamily
BJD12_RS07660	COG0583	DNA-binding transcription factor activity
BJD12_RS07670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BJD12_RS07675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BJD12_RS07680	COG2390	Transcriptional regulator
BJD12_RS07690	COG3659	wide pore channel activity
BJD12_RS07710	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS07730	COG1561	YicC-like family, N-terminal region
BJD12_RS07735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BJD12_RS07745	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BJD12_RS07750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BJD12_RS07765	COG0006	proline dipeptidase activity
BJD12_RS07780	COG0006	proline dipeptidase activity
BJD12_RS07805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BJD12_RS07825	COG2912	Transglutaminase-like superfamily
BJD12_RS07830	COG1773	rubredoxin
BJD12_RS07835	COG0352	thiamine-phosphate diphosphorylase activity
BJD12_RS07920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BJD12_RS08070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BJD12_RS08085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJD12_RS08120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BJD12_RS08125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BJD12_RS08155	COG0671	phosphoesterase, PA-phosphatase related
BJD12_RS08160	COG3781	membrane
BJD12_RS08170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BJD12_RS08175	COG0563	adenylate kinase activity
BJD12_RS08195	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BJD12_RS08205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BJD12_RS08225	COG3710	Transcriptional regulator
BJD12_RS08235	COG0823	Involved in the tonB-independent uptake of proteins
BJD12_RS08235	COG4946	Tricorn protease homolog
BJD12_RS08235	COG1506	peptidase
BJD12_RS08240	COG0840	transmembrane signaling receptor activity
BJD12_RS08245	COG0405	Gamma-glutamyltransferase
BJD12_RS08250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BJD12_RS08270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BJD12_RS08280	COG0473	3-isopropylmalate dehydrogenase activity
BJD12_RS08285	COG2226	methyltransferase
BJD12_RS08290	COG0066	3-isopropylmalate dehydratase activity
BJD12_RS08295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BJD12_RS08315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BJD12_RS08320	COG1538	Outer membrane efflux protein
BJD12_RS08325	COG1519	Transferase
BJD12_RS08330	COG1560	Kdo2-lipid A biosynthetic process
BJD12_RS08355	COG0281	malic enzyme
BJD12_RS08355	COG0280	phosphate acetyltransferase
BJD12_RS08370	COG4191	Histidine kinase
BJD12_RS08385	COG0667	Aldo Keto reductase
BJD12_RS08400	COG2197	response regulator
BJD12_RS08410	COG0642	Histidine kinase
BJD12_RS08425	COG2851	Citrate transporter
BJD12_RS08430	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS08435	COG1609	Transcriptional regulator
BJD12_RS08440	COG2211	Major facilitator Superfamily
BJD12_RS08470	COG0436	Aminotransferase
BJD12_RS08485	COG0726	polysaccharide deacetylase
BJD12_RS08490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BJD12_RS08505	COG3964	amidohydrolase
BJD12_RS08510	COG0402	S-adenosylhomocysteine deaminase activity
BJD12_RS08550	COG1307	EDD domain protein, DegV family
BJD12_RS08565	COG3791	Glutathione-dependent formaldehyde-activating
BJD12_RS08580	COG0583	DNA-binding transcription factor activity
BJD12_RS08600	COG2205	protein histidine kinase activity
BJD12_RS08630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BJD12_RS08645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BJD12_RS08655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BJD12_RS08660	COG1012	belongs to the aldehyde dehydrogenase family
BJD12_RS08665	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BJD12_RS08715	COG1183	phosphatidylcholine synthase activity
BJD12_RS08725	COG0442	prolyl-tRNA aminoacylation
BJD12_RS08740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BJD12_RS08745	COG1127	ABC transporter
BJD12_RS08750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BJD12_RS08750	COG3218	ABC-type transport auxiliary lipoprotein component
BJD12_RS08780	COG3754	Rhamnan synthesis protein F
BJD12_RS08795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BJD12_RS08800	COG0662	Cupin 2, conserved barrel domain protein
BJD12_RS08800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BJD12_RS08830	COG2086	electron transfer activity
BJD12_RS08845	COG0463	Glycosyl transferase, family 2
BJD12_RS08870	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BJD12_RS08910	COG0626	cystathionine gamma-synthase activity
BJD12_RS08940	COG0625	glutathione transferase activity
BJD12_RS08955	COG0513	Belongs to the DEAD box helicase family
BJD12_RS08960	COG0720	synthase
BJD12_RS08970	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BJD12_RS08975	COG1956	GAF domain-containing protein
BJD12_RS08990	COG0546	phosphoglycolate phosphatase activity
BJD12_RS09000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BJD12_RS09025	COG0339	signal peptide processing
BJD12_RS09075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BJD12_RS09080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BJD12_RS09085	COG4591	ABC-type transport system involved in lipoprotein release permease component
BJD12_RS09085	COG1136	(ABC) transporter
BJD12_RS09090	COG0577	efflux transmembrane transporter activity
BJD12_RS09110	COG4191	Histidine kinase
BJD12_RS09120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BJD12_RS09135	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BJD12_RS09145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BJD12_RS09150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BJD12_RS09155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BJD12_RS09160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BJD12_RS09170	COG0356	it plays a direct role in the translocation of protons across the membrane
BJD12_RS09185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BJD12_RS09195	COG0508	dehydrogenase complex catalyzes the overall conversion of
BJD12_RS09225	COG2011	ABC-type metal ion transport system permease component
BJD12_RS09230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BJD12_RS09235	COG0697	spore germination
BJD12_RS09240	COG1666	GTP binding
BJD12_RS09270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BJD12_RS09275	COG1187	pseudouridine synthase activity
BJD12_RS09280	COG2813	Specifically methylates the guanine in position
BJD12_RS09300	COG2205	protein histidine kinase activity
BJD12_RS09300	COG0784	Response regulator, receiver
BJD12_RS09320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BJD12_RS09325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BJD12_RS09380	COG0842	Transport permease protein
BJD12_RS09385	COG1131	(ABC) transporter
BJD12_RS09390	COG0025	NhaP-type Na H and K H
BJD12_RS09410	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BJD12_RS09415	COG1573	uracil-dna glycosylase
BJD12_RS09430	COG3384	dioxygenase
BJD12_RS09440	COG0583	DNA-binding transcription factor activity
BJD12_RS09460	COG0667	Aldo Keto reductase
BJD12_RS09470	COG3590	peptidase
BJD12_RS09490	COG0531	amino acid
BJD12_RS09505	COG3275	phosphorelay sensor kinase activity
BJD12_RS09520	COG3685	Protein conserved in bacteria
BJD12_RS09525	COG3546	catalase activity
BJD12_RS09555	COG2204	response regulator
BJD12_RS09565	COG1271	oxidase subunit
BJD12_RS09570	COG1294	oxidase, subunit
BJD12_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS09595	COG1063	alcohol dehydrogenase
BJD12_RS09620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BJD12_RS09670	COG1131	(ABC) transporter
BJD12_RS09680	COG0251	oxidation-reduction process
BJD12_RS09685	COG0840	transmembrane signaling receptor activity
BJD12_RS09710	COG0038	chloride channel
BJD12_RS09720	COG0024	Methionine aminopeptidase
BJD12_RS09730	COG1733	regulation of RNA biosynthetic process
BJD12_RS09740	COG1999	signal sequence binding
BJD12_RS09750	COG1335	isochorismatase
BJD12_RS09805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BJD12_RS09810	COG1490	D-aminoacyl-tRNA deacylase activity
BJD12_RS09815	COG1560	Kdo2-lipid A biosynthetic process
BJD12_RS09820	COG1247	-acetyltransferase
BJD12_RS09865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BJD12_RS09870	COG0242	peptide deformylase activity
BJD12_RS09875	COG1652	LysM domain
BJD12_RS09880	COG0758	DNA mediated transformation
BJD12_RS09900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BJD12_RS09900	COG1754	DNA topoisomerase type I activity
BJD12_RS09905	COG0009	L-threonylcarbamoyladenylate synthase
BJD12_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS09930	COG0616	signal peptide processing
BJD12_RS09935	COG0534	Mate efflux family protein
BJD12_RS09955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BJD12_RS09960	COG0625	glutathione transferase activity
BJD12_RS09975	COG1252	NADH dehydrogenase
BJD12_RS09980	COG2860	membrane
BJD12_RS09985	COG2860	membrane
BJD12_RS09990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BJD12_RS10000	COG3437	response regulator, receiver
BJD12_RS10005	COG2177	Part of the ABC transporter FtsEX involved in
BJD12_RS10010	COG2884	Cell division ATP-binding protein ftsE
BJD12_RS10020	COG3118	belongs to the thioredoxin family
BJD12_RS10025	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BJD12_RS10035	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BJD12_RS10040	COG0583	DNA-binding transcription factor activity
BJD12_RS10060	COG1652	LysM domain
BJD12_RS10065	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BJD12_RS10065	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BJD12_RS10070	COG1473	amidohydrolase
BJD12_RS10075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BJD12_RS10100	COG5383	Protein conserved in bacteria
BJD12_RS10140	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BJD12_RS10145	COG3023	N-Acetylmuramoyl-L-alanine amidase
BJD12_RS10155	COG4948	Mandelate Racemase Muconate Lactonizing
BJD12_RS10165	COG0531	amino acid
BJD12_RS10180	COG4682	membrane
BJD12_RS10185	COG2133	pyrroloquinoline quinone binding
BJD12_RS10195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BJD12_RS10200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BJD12_RS10210	COG1610	YqeY-like protein
BJD12_RS10215	COG1295	ribonuclease BN
BJD12_RS10220	COG0358	DNA primase activity
BJD12_RS10275	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BJD12_RS10290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BJD12_RS10335	COG0739	heme binding
BJD12_RS10350	COG2211	Major facilitator Superfamily
BJD12_RS10360	COG0708	Exodeoxyribonuclease III
BJD12_RS10375	COG1192	Involved in chromosome partitioning
BJD12_RS10380	COG1475	DNA binding
BJD12_RS10400	COG0463	Glycosyl transferase, family 2
BJD12_RS10420	COG0756	dUTP diphosphatase activity
BJD12_RS10425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BJD12_RS10450	COG4221	oxidoreductase activity
BJD12_RS10455	COG2755	lipolytic protein G-D-S-L family
BJD12_RS10455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BJD12_RS10475	COG1166	arginine decarboxylase activity
BJD12_RS10480	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BJD12_RS10500	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BJD12_RS10500	COG3291	Pkd domain containing protein
BJD12_RS10510	COG2960	long-chain fatty acid transporting porin activity
BJD12_RS10515	COG0606	chelatase, subunit chli
BJD12_RS10530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BJD12_RS10560	COG1690	Belongs to the RtcB family
BJD12_RS10595	COG1090	epimerase
BJD12_RS10605	COG0642	Histidine kinase
BJD12_RS10625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BJD12_RS10645	COG0628	permease
BJD12_RS10655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BJD12_RS10665	COG0753	catalase activity
BJD12_RS10680	COG2197	response regulator
BJD12_RS10690	COG4585	Histidine kinase
BJD12_RS10695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BJD12_RS10700	COG1136	(ABC) transporter
BJD12_RS10725	COG0697	spore germination
BJD12_RS10745	COG0180	Tryptophanyl-tRNA synthetase
BJD12_RS10750	COG3237	CsbD-like
BJD12_RS10790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BJD12_RS10805	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BJD12_RS10810	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BJD12_RS10810	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BJD12_RS10850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BJD12_RS10880	COG1199	ATP-dependent helicase activity
BJD12_RS10905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BJD12_RS10950	COG0625	glutathione transferase activity
BJD12_RS10985	COG4555	ABC transporter
BJD12_RS10995	COG1476	TRANSCRIPTIONal
BJD12_RS11020	COG0633	Ferredoxin
BJD12_RS11020	COG0543	2 iron, 2 sulfur cluster binding
BJD12_RS11025	COG1131	(ABC) transporter
BJD12_RS11030	COG0842	Transport permease protein
BJD12_RS11035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BJD12_RS11045	COG1607	acyl-coa hydrolase
BJD12_RS11065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BJD12_RS11070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BJD12_RS11085	COG0045	succinate-CoA ligase (ADP-forming) activity
BJD12_RS11085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BJD12_RS11085	COG1042	CoA-binding domain protein
BJD12_RS11090	COG2239	Acts as a magnesium transporter
BJD12_RS11100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BJD12_RS11100	COG0475	glutathione-regulated potassium exporter activity
BJD12_RS11105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BJD12_RS11110	COG3387	PFAM Glycoside hydrolase 15-related
BJD12_RS11125	COG3100	YcgL domain-containing protein
BJD12_RS11130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BJD12_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS11175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BJD12_RS11190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BJD12_RS11240	COG0408	coproporphyrinogen oxidase activity
BJD12_RS11275	COG0515	serine threonine protein kinase
BJD12_RS11275	COG2815	serine threonine protein kinase
BJD12_RS11280	COG0631	protein serine/threonine phosphatase activity
BJD12_RS11310	COG0667	Aldo Keto reductase
BJD12_RS11315	COG0583	DNA-binding transcription factor activity
BJD12_RS11460	COG0210	DNA helicase
BJD12_RS11475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BJD12_RS11480	COG0583	DNA-binding transcription factor activity
BJD12_RS11485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BJD12_RS11495	COG2159	amidohydrolase
BJD12_RS11540	COG0357	Ribosomal RNA small subunit methyltransferase G
BJD12_RS11550	COG2091	lysine biosynthetic process via aminoadipic acid
BJD12_RS11575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BJD12_RS11580	COG3162	membrane
BJD12_RS11620	COG3507	Belongs to the glycosyl hydrolase 43 family
BJD12_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS11640	COG0179	Fumarylacetoacetate (FAA) hydrolase
BJD12_RS11645	COG4948	Mandelate Racemase Muconate Lactonizing
BJD12_RS11650	COG3254	rhamnose metabolic process
BJD12_RS11655	COG0738	Major facilitator superfamily
BJD12_RS11660	COG1414	Transcriptional regulator
BJD12_RS11670	COG2205	protein histidine kinase activity
BJD12_RS11670	COG0784	Response regulator, receiver
BJD12_RS11685	COG3459	Glycosyltransferase 36 associated
BJD12_RS11690	COG2211	Major facilitator Superfamily
BJD12_RS11695	COG3265	gluconokinase activity
BJD12_RS11700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BJD12_RS11720	COG2911	Protein conserved in bacteria
BJD12_RS11725	COG0729	surface antigen
BJD12_RS11730	COG4771	TonB-dependent receptor
BJD12_RS11735	COG0457	Tetratricopeptide repeat
BJD12_RS11750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BJD12_RS11760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BJD12_RS11760	COG0519	Catalyzes the synthesis of GMP from XMP
BJD12_RS11775	COG0805	protein transport
BJD12_RS11785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BJD12_RS11795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BJD12_RS11815	COG2974	May be involved in recombination
BJD12_RS11820	COG0037	tRNA processing
BJD12_RS11830	COG2115	Belongs to the xylose isomerase family
BJD12_RS11840	COG3661	Belongs to the glycosyl hydrolase 67 family
BJD12_RS11850	COG4948	Mandelate Racemase Muconate Lactonizing
BJD12_RS11860	COG1472	Belongs to the glycosyl hydrolase 3 family
BJD12_RS11865	COG0246	Mannitol dehydrogenase
BJD12_RS11895	COG3386	PFAM SMP-30 Gluconolaconase
BJD12_RS11905	COG3250	beta-galactosidase activity
BJD12_RS11910	COG1904	glucuronate isomerase
BJD12_RS11915	COG3693	PFAM glycoside hydrolase, family 10
BJD12_RS11930	COG2211	Major facilitator Superfamily
BJD12_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS11965	COG3321	synthase
BJD12_RS11965	COG0604	alcohol dehydrogenase
BJD12_RS11970	COG2937	Belongs to the GPAT DAPAT family
BJD12_RS12005	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BJD12_RS12010	COG3132	Protein of unknown function, DUF480
BJD12_RS12025	COG0210	DNA helicase
BJD12_RS12030	COG1435	thymidine kinase activity
BJD12_RS12040	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BJD12_RS12050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BJD12_RS12080	COG3135	benzoate transporter
BJD12_RS12100	COG0676	glucose-6-phosphate 1-epimerase activity
BJD12_RS12115	COG0730	response to heat
BJD12_RS12135	COG0302	gtp cyclohydrolase
BJD12_RS12150	COG1566	PFAM secretion protein HlyD family protein
BJD12_RS12160	COG1289	transmembrane transporter activity
BJD12_RS12165	COG0477	Major facilitator Superfamily
BJD12_RS12175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BJD12_RS12235	COG0564	pseudouridine synthase activity
BJD12_RS12285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BJD12_RS12290	COG1074	ATP-dependent DNA helicase activity
BJD12_RS12295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BJD12_RS12335	COG1127	ABC transporter
BJD12_RS12340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BJD12_RS12345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BJD12_RS12360	COG2853	Lipoprotein
BJD12_RS12370	COG0386	Belongs to the glutathione peroxidase family
BJD12_RS12380	COG1322	Protein conserved in bacteria
BJD12_RS12385	COG0604	alcohol dehydrogenase
BJD12_RS12400	COG0625	glutathione transferase activity
BJD12_RS12410	COG0531	amino acid
BJD12_RS12415	COG3537	Alpha-1,2-mannosidase
BJD12_RS12420	COG4206	TonB-dependent receptor
BJD12_RS12430	COG3706	GGDEF domain
BJD12_RS12435	COG1929	Belongs to the glycerate kinase type-1 family
BJD12_RS12455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BJD12_RS12465	COG0861	Integral membrane protein TerC family
BJD12_RS12480	COG0584	glycerophosphoryl diester phosphodiesterase
BJD12_RS12495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BJD12_RS12505	COG0726	polysaccharide deacetylase
BJD12_RS12510	COG0706	membrane insertase activity
BJD12_RS12530	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BJD12_RS12540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BJD12_RS12545	COG0187	DNA topoisomerase II activity
BJD12_RS12555	COG0501	Belongs to the peptidase M48B family
BJD12_RS12600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BJD12_RS12610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BJD12_RS12645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BJD12_RS12650	COG0793	Belongs to the peptidase S41A family
BJD12_RS12660	COG4942	peptidase
BJD12_RS12670	COG2234	aminopeptidase activity
BJD12_RS12680	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BJD12_RS12685	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BJD12_RS12690	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BJD12_RS12695	COG1064	alcohol dehydrogenase
BJD12_RS12700	COG0493	'glutamate synthase
BJD12_RS12705	COG0070	glutamate synthase
BJD12_RS12705	COG0069	glutamate synthase activity
BJD12_RS12705	COG0067	glutamate synthase
BJD12_RS12750	COG0583	DNA-binding transcription factor activity
BJD12_RS12825	COG1205	dead DEAH box helicase
BJD12_RS12825	COG1111	helicase
BJD12_RS12830	COG1272	protein, Hemolysin III
BJD12_RS12840	COG0625	glutathione transferase activity
BJD12_RS12850	COG3590	peptidase
BJD12_RS12855	COG0583	DNA-binding transcription factor activity
BJD12_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS12880	COG2249	NAD(P)H dehydrogenase (quinone) activity
BJD12_RS12890	COG1733	regulation of RNA biosynthetic process
BJD12_RS12925	COG3237	CsbD-like
BJD12_RS12970	COG1309	transcriptional regulator
BJD12_RS12990	COG0628	permease
BJD12_RS12995	COG0657	acetylesterase activity
BJD12_RS13005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJD12_RS13010	COG0477	Major facilitator Superfamily
BJD12_RS13055	COG0714	Associated with various cellular activities
BJD12_RS13090	COG0596	Alpha beta hydrolase
BJD12_RS13100	COG1309	transcriptional regulator
BJD12_RS13105	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BJD12_RS13115	COG4772	TonB-dependent receptor
BJD12_RS13135	COG1012	belongs to the aldehyde dehydrogenase family
BJD12_RS13180	COG1755	Isoprenylcysteine carboxyl methyltransferase
BJD12_RS13185	COG4585	Histidine kinase
BJD12_RS13190	COG2197	response regulator
BJD12_RS13200	COG3710	Transcriptional regulator
BJD12_RS13205	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BJD12_RS13215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD12_RS13315	COG0366	Alpha amylase catalytic
BJD12_RS13320	COG0366	Alpha amylase catalytic
BJD12_RS13360	COG2755	lipolytic protein G-D-S-L family
BJD12_RS13370	COG0657	acetylesterase activity
BJD12_RS13370	COG2755	lipolytic protein G-D-S-L family
BJD12_RS13380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BJD12_RS13395	COG3507	Belongs to the glycosyl hydrolase 43 family
BJD12_RS13400	COG1609	Transcriptional regulator
BJD12_RS13410	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BJD12_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS13425	COG2755	lipolytic protein G-D-S-L family
BJD12_RS13435	COG3186	Phenylalanine-4-hydroxylase
BJD12_RS13440	COG1522	sequence-specific DNA binding
BJD12_RS13455	COG1752	Esterase of the alpha-beta hydrolase superfamily
BJD12_RS13465	COG1119	ATPase activity
BJD12_RS13480	COG0517	IMP dehydrogenase activity
BJD12_RS13480	COG1125	glycine betaine transport
BJD12_RS13495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BJD12_RS13500	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BJD12_RS13525	COG0489	protein tyrosine kinase activity
BJD12_RS13530	COG2062	phosphohistidine phosphatase, SixA
BJD12_RS13535	COG2353	YceI-like domain
BJD12_RS13540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BJD12_RS13550	COG2050	protein possibly involved in aromatic compounds catabolism
BJD12_RS13570	COG1881	PFAM PEBP family protein
BJD12_RS13590	COG0174	glutamine synthetase
BJD12_RS13595	COG0347	Belongs to the P(II) protein family
BJD12_RS13600	COG0004	ammonium transporteR
BJD12_RS13605	COG3852	Histidine kinase
BJD12_RS13610	COG2204	response regulator
BJD12_RS13615	COG2032	superoxide dismutase activity
BJD12_RS13620	COG2032	superoxide dismutase activity
BJD12_RS13635	COG0183	Belongs to the thiolase family
BJD12_RS13675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BJD12_RS13680	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BJD12_RS13685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BJD12_RS13695	COG0028	Belongs to the TPP enzyme family
BJD12_RS13700	COG2205	protein histidine kinase activity
BJD12_RS13725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BJD12_RS13740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BJD12_RS13745	COG3177	Filamentation induced by cAMP protein fic
BJD12_RS13750	COG0596	Alpha beta hydrolase
BJD12_RS13755	COG0727	PFAM Uncharacterised protein family (UPF0153)
BJD12_RS13760	COG0318	PFAM AMP-dependent synthetase and ligase
BJD12_RS13765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BJD12_RS13780	COG1181	Belongs to the D-alanine--D-alanine ligase family
BJD12_RS13790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BJD12_RS13800	COG0564	pseudouridine synthase activity
BJD12_RS13830	COG0339	signal peptide processing
BJD12_RS13835	COG0339	signal peptide processing
BJD12_RS13865	COG0475	glutathione-regulated potassium exporter activity
BJD12_RS13870	COG0583	DNA-binding transcription factor activity
BJD12_RS13875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BJD12_RS13880	COG2224	Isocitrate lyase
BJD12_RS13915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BJD12_RS13920	COG1960	acyl-CoA dehydrogenase activity
BJD12_RS13980	COG0523	cobalamin synthesis protein
BJD12_RS13995	COG0697	spore germination
BJD12_RS14005	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BJD12_RS14010	COG1846	Transcriptional regulator
BJD12_RS14015	COG1764	response to oxidative stress
BJD12_RS14025	COG2267	carboxylic ester hydrolase activity
BJD12_RS14045	COG0656	L-ascorbic acid biosynthetic process
BJD12_RS14050	COG2130	NADP-dependent
BJD12_RS14065	COG1187	pseudouridine synthase activity
BJD12_RS14080	COG1643	Atp-dependent helicase
BJD12_RS14085	COG0840	transmembrane signaling receptor activity
BJD12_RS14090	COG4807	Protein conserved in bacteria
BJD12_RS14095	COG2351	hydroxyisourate hydrolase activity
BJD12_RS14100	COG2072	flavoprotein involved in K transport
BJD12_RS14120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BJD12_RS14160	COG1957	nucleoside hydrolase
BJD12_RS14170	COG2252	PERMEase
BJD12_RS14185	COG0583	DNA-binding transcription factor activity
BJD12_RS14190	COG0084	hydrolase, TatD family'
BJD12_RS14205	COG0583	DNA-binding transcription factor activity
BJD12_RS14210	COG2814	Major facilitator Superfamily
BJD12_RS14225	COG4221	oxidoreductase activity
BJD12_RS14240	COG1902	pentaerythritol trinitrate reductase activity
BJD12_RS14265	COG0300	oxidoreductase activity
BJD12_RS14280	COG0583	DNA-binding transcription factor activity
BJD12_RS14295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BJD12_RS14315	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS14320	COG0604	alcohol dehydrogenase
BJD12_RS14320	COG3321	synthase
BJD12_RS14325	COG3321	synthase
BJD12_RS14325	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS14325	COG0604	alcohol dehydrogenase
BJD12_RS14340	COG0702	epimerase
BJD12_RS14345	COG1733	regulation of RNA biosynthetic process
BJD12_RS14350	COG0840	transmembrane signaling receptor activity
BJD12_RS14455	COG0129	dihydroxy-acid dehydratase activity
BJD12_RS14465	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BJD12_RS14520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BJD12_RS14525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BJD12_RS14555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BJD12_RS14560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BJD12_RS14570	COG3485	protocatechuate 3,4-dioxygenase
BJD12_RS14575	COG3485	protocatechuate 3,4-dioxygenase
BJD12_RS14585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BJD12_RS14590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BJD12_RS14600	COG1414	Transcriptional regulator
BJD12_RS14610	COG0657	acetylesterase activity
BJD12_RS14620	COG0445	tRNA wobble uridine modification
BJD12_RS14630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BJD12_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS14675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BJD12_RS14680	COG1040	competence protein
BJD12_RS14705	COG0840	transmembrane signaling receptor activity
BJD12_RS14720	COG1511	domain protein
BJD12_RS14720	COG3264	Mechanosensitive ion channel
BJD12_RS14725	COG1368	sulfuric ester hydrolase activity
BJD12_RS14735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BJD12_RS14740	COG2354	Protein conserved in bacteria
BJD12_RS14750	COG0297	glycogen (starch) synthase activity
BJD12_RS14760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BJD12_RS14785	COG0702	epimerase
BJD12_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS14825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BJD12_RS14835	COG4221	oxidoreductase activity
BJD12_RS14850	COG0513	Belongs to the DEAD box helicase family
BJD12_RS14865	COG0508	dehydrogenase complex catalyzes the overall conversion of
BJD12_RS14880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BJD12_RS14895	COG3104	oligopeptide transport
BJD12_RS14915	COG2852	Protein conserved in bacteria
BJD12_RS14935	COG1320	monovalent cation:proton antiporter activity
BJD12_RS14940	COG2212	antiporter activity
BJD12_RS14950	COG0651	ATP synthesis coupled electron transport
BJD12_RS14955	COG1006	Multisubunit Na H antiporter MnhC subunit
BJD12_RS14960	COG2111	Na H antiporter
BJD12_RS14960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BJD12_RS14995	COG0484	heat shock protein binding
BJD12_RS15015	COG0456	acetyltransferase
BJD12_RS15020	COG1597	lipid kinase activity
BJD12_RS15055	COG0134	indole-3-glycerol-phosphate synthase activity
BJD12_RS15065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BJD12_RS15080	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BJD12_RS15090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BJD12_RS15125	COG0745	RESPONSE REGULATOR receiver
BJD12_RS15145	COG0316	Belongs to the HesB IscA family
BJD12_RS15150	COG2816	NAD+ diphosphatase activity
BJD12_RS15155	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BJD12_RS15180	COG2814	Major facilitator Superfamily
BJD12_RS15185	COG1289	transmembrane transporter activity
BJD12_RS15190	COG0151	Belongs to the GarS family
BJD12_RS15205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BJD12_RS15210	COG2267	carboxylic ester hydrolase activity
BJD12_RS15215	COG0671	phosphoesterase, PA-phosphatase related
BJD12_RS15215	COG2453	phosphatase
BJD12_RS15240	COG4589	Belongs to the CDS family
BJD12_RS15250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BJD12_RS15270	COG2264	protein methyltransferase activity
BJD12_RS15285	COG0439	Biotin carboxylase
BJD12_RS15295	COG0511	ligase activity, forming carbon-carbon bonds
BJD12_RS15300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BJD12_RS15310	COG1324	tolerance protein
BJD12_RS15315	COG2356	endonuclease I
BJD12_RS15325	COG0459	protein refolding
BJD12_RS15345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BJD12_RS15365	COG3386	PFAM SMP-30 Gluconolaconase
BJD12_RS15375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BJD12_RS15420	COG0778	Nitroreductase
BJD12_RS15425	COG2353	YceI-like domain
BJD12_RS15445	COG3052	prosthetic group binding
BJD12_RS15480	COG1802	Transcriptional regulator
BJD12_RS15555	COG2963	transposase activity
BJD12_RS15675	COG0435	Glutathione S-transferase
BJD12_RS15720	COG2409	Drug exporters of the RND superfamily
BJD12_RS15750	COG1959	2 iron, 2 sulfur cluster binding
BJD12_RS15755	COG3634	alkyl hydroperoxide reductase activity
BJD12_RS15780	COG0697	spore germination
BJD12_RS15795	COG1113	amino acid transport
BJD12_RS15865	COG0840	transmembrane signaling receptor activity
BJD12_RS15870	COG5297	Belongs to the glycosyl hydrolase family 6
BJD12_RS15870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BJD12_RS15875	COG0659	secondary active sulfate transmembrane transporter activity
BJD12_RS15920	COG2943	transferase activity, transferring hexosyl groups
BJD12_RS15930	COG3275	phosphorelay sensor kinase activity
BJD12_RS15940	COG0181	hydroxymethylbilane synthase activity
BJD12_RS15970	COG1505	serine-type exopeptidase activity
BJD12_RS15985	COG0436	Aminotransferase
BJD12_RS16000	COG2832	Protein of unknown function (DUF454)
BJD12_RS16010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BJD12_RS16020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BJD12_RS16030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BJD12_RS16035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BJD12_RS16050	COG2153	protein acetylation
BJD12_RS16065	COG2226	methyltransferase
BJD12_RS16070	COG3300	MHYT domain
BJD12_RS16070	COG5001	Diguanylate cyclase
BJD12_RS16075	COG0308	aminopeptidase N
BJD12_RS16110	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BJD12_RS16120	COG3284	Transcriptional regulator
BJD12_RS16125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD12_RS16130	COG1077	Cell shape determining protein MreB Mrl
BJD12_RS16135	COG1792	Involved in formation and maintenance of cell shape
BJD12_RS16150	COG0772	Belongs to the SEDS family
BJD12_RS16160	COG2951	lytic endotransglycosylase activity
BJD12_RS16165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BJD12_RS16170	COG1686	Belongs to the peptidase S11 family
BJD12_RS16180	COG2921	Belongs to the UPF0250 family
BJD12_RS16185	COG0321	lipoyl(octanoyl) transferase activity
BJD12_RS16190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BJD12_RS16205	COG0583	DNA-binding transcription factor activity
BJD12_RS16215	COG1051	belongs to the nudix hydrolase family
BJD12_RS16215	COG1056	cytidyltransferase-related domain
BJD12_RS16250	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BJD12_RS16255	COG0673	inositol 2-dehydrogenase activity
BJD12_RS16260	COG2823	Periplasmic or secreted lipoprotein
BJD12_RS16265	COG4251	negative regulation of phosphorylation
BJD12_RS16270	COG0784	Response regulator, receiver
BJD12_RS16275	COG4191	Histidine kinase
BJD12_RS16280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BJD12_RS16285	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS16340	COG2165	general secretion pathway protein
BJD12_RS16355	COG4795	General secretion pathway protein
BJD12_RS16360	COG3156	type II secretion system protein K
BJD12_RS16380	COG2188	Transcriptional regulator
BJD12_RS16390	COG1609	Transcriptional regulator
BJD12_RS16395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BJD12_RS16400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BJD12_RS16415	COG0617	tRNA 3'-terminal CCA addition
BJD12_RS16430	COG0525	valine-tRNA ligase activity
BJD12_RS16445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BJD12_RS16455	COG0795	lipopolysaccharide-transporting ATPase activity
BJD12_RS16470	COG4974	Belongs to the 'phage' integrase family
BJD12_RS16475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BJD12_RS16485	COG0047	phosphoribosylformylglycinamidine synthase activity
BJD12_RS16485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BJD12_RS16495	COG5295	Hep Hag repeat protein
BJD12_RS16500	COG1404	Belongs to the peptidase S8 family
BJD12_RS16505	COG1404	Belongs to the peptidase S8 family
BJD12_RS16510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BJD12_RS16515	COG1459	type II secretion system
BJD12_RS16520	COG2165	general secretion pathway protein
BJD12_RS16525	COG4970	Tfp pilus assembly protein FimT
BJD12_RS16530	COG2165	general secretion pathway protein
BJD12_RS16535	COG4795	General secretion pathway protein
BJD12_RS16540	COG3156	type II secretion system protein K
BJD12_RS16545	COG3166	PFAM Fimbrial assembly family protein
BJD12_RS16560	COG1450	Type ii and iii secretion system protein
BJD12_RS16580	COG2188	Transcriptional regulator
BJD12_RS16625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BJD12_RS16640	COG1215	transferase activity, transferring glycosyl groups
BJD12_RS16645	COG1215	transferase activity, transferring glycosyl groups
BJD12_RS16650	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BJD12_RS16655	COG0457	Tetratricopeptide repeat
BJD12_RS16675	COG0242	peptide deformylase activity
BJD12_RS16680	COG0488	(ABC) transporter
BJD12_RS16690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BJD12_RS16705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BJD12_RS16705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BJD12_RS16735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BJD12_RS16765	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BJD12_RS16770	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BJD12_RS16780	COG2205	protein histidine kinase activity
BJD12_RS16785	COG0745	RESPONSE REGULATOR receiver
BJD12_RS16790	COG4946	Tricorn protease homolog
BJD12_RS16790	COG0823	Involved in the tonB-independent uptake of proteins
BJD12_RS16790	COG1506	peptidase
BJD12_RS16795	COG0277	FAD linked oxidase domain protein
BJD12_RS16800	COG1988	membrane-bound metal-dependent
BJD12_RS16805	COG0792	nuclease activity
BJD12_RS16850	COG3116	cell division
BJD12_RS16860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BJD12_RS16865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BJD12_RS16870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BJD12_RS16885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BJD12_RS16890	COG1181	Belongs to the D-alanine--D-alanine ligase family
BJD12_RS16895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BJD12_RS16920	COG0739	heme binding
BJD12_RS16940	COG0494	nUDIX hydrolase
BJD12_RS16955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BJD12_RS16965	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS16965	COG3321	synthase
BJD12_RS16965	COG0604	alcohol dehydrogenase
BJD12_RS16995	COG0366	Alpha amylase catalytic
BJD12_RS17025	COG2226	methyltransferase
BJD12_RS17040	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BJD12_RS17060	COG2885	chlorophyll binding
BJD12_RS17080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BJD12_RS17090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BJD12_RS17100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD12_RS17105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BJD12_RS17110	COG0667	Aldo Keto reductase
BJD12_RS17120	COG4771	TonB-dependent receptor
BJD12_RS17140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BJD12_RS17145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BJD12_RS17155	COG2175	clavaminate synthase activity
BJD12_RS17165	COG4181	ATPase activity
BJD12_RS17180	COG0642	Histidine kinase
BJD12_RS17190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BJD12_RS17200	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BJD12_RS17210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BJD12_RS17230	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BJD12_RS17235	COG2967	ApaG domain
BJD12_RS17240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BJD12_RS17245	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BJD12_RS17255	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BJD12_RS17265	COG2096	Adenosyltransferase
BJD12_RS17275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BJD12_RS17280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BJD12_RS17310	COG3384	dioxygenase
BJD12_RS17315	COG0583	DNA-binding transcription factor activity
BJD12_RS17320	COG0318	PFAM AMP-dependent synthetase and ligase
BJD12_RS17330	COG1024	Enoyl-CoA hydratase
BJD12_RS17380	COG0697	spore germination
BJD12_RS17385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BJD12_RS17405	COG2205	protein histidine kinase activity
BJD12_RS17405	COG5002	protein histidine kinase activity
BJD12_RS17405	COG0784	Response regulator, receiver
BJD12_RS17410	COG2197	response regulator
BJD12_RS17420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BJD12_RS17430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BJD12_RS17435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BJD12_RS17440	COG0583	DNA-binding transcription factor activity
BJD12_RS17445	COG3634	alkyl hydroperoxide reductase activity
BJD12_RS17455	COG2890	protein-(glutamine-N5) methyltransferase activity
BJD12_RS17480	COG0778	Nitroreductase
BJD12_RS17505	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BJD12_RS17530	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BJD12_RS17550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BJD12_RS17555	COG1404	Belongs to the peptidase S8 family
BJD12_RS17560	COG1404	Belongs to the peptidase S8 family
BJD12_RS17565	COG1404	Belongs to the peptidase S8 family
BJD12_RS17575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BJD12_RS17595	COG1295	ribonuclease BN
BJD12_RS17600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJD12_RS17605	COG1254	Belongs to the acylphosphatase family
BJD12_RS17620	COG0521	Mo-molybdopterin cofactor biosynthetic process
BJD12_RS17630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BJD12_RS17645	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BJD12_RS17650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BJD12_RS17660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BJD12_RS17665	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BJD12_RS17670	COG0193	aminoacyl-tRNA hydrolase activity
BJD12_RS17675	COG0012	GTP binding
BJD12_RS17680	COG0582	viral genome integration into host DNA
BJD12_RS17735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BJD12_RS17750	COG0250	Participates in transcription elongation, termination and antitermination
BJD12_RS17755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BJD12_RS17760	COG0081	regulation of translation
BJD12_RS17765	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BJD12_RS17770	COG0222	ribosome binding
BJD12_RS17780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BJD12_RS17795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BJD12_RS17800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BJD12_RS17805	COG0051	transcription antitermination factor activity, RNA binding
BJD12_RS17825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BJD12_RS17845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BJD12_RS17850	COG0255	Belongs to the universal ribosomal protein uL29 family
BJD12_RS17855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BJD12_RS17865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BJD12_RS17900	COG1841	ribosomal large subunit assembly
BJD12_RS17905	COG0200	Binds to the 23S rRNA
BJD12_RS17910	COG0201	protein transport
BJD12_RS17935	COG0203	ribosomal protein L17
BJD12_RS17940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BJD12_RS17950	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BJD12_RS17960	COG0154	amidase activity
BJD12_RS17970	COG1217	gtp-binding protein TYPA
BJD12_RS17975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BJD12_RS17980	COG0039	L-malate dehydrogenase activity
BJD12_RS17985	COG0625	glutathione transferase activity
BJD12_RS18000	COG1902	pentaerythritol trinitrate reductase activity
BJD12_RS18000	COG0446	pyridine nucleotide-disulphide oxidoreductase
BJD12_RS18005	COG0604	alcohol dehydrogenase
BJD12_RS18015	COG2885	chlorophyll binding
BJD12_RS18040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BJD12_RS18045	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BJD12_RS18050	COG4208	sulfate ABC transporter
BJD12_RS18055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BJD12_RS18090	COG0406	alpha-ribazole phosphatase activity
BJD12_RS18100	COG0285	dihydrofolate synthase activity
BJD12_RS18120	COG2833	Protein of unknown function (DUF455)
BJD12_RS18125	COG3291	Pkd domain containing protein
BJD12_RS18135	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BJD12_RS18140	COG0671	phosphoesterase, PA-phosphatase related
BJD12_RS18155	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BJD12_RS18170	COG4783	chaperone-mediated protein folding
BJD12_RS18185	COG0473	3-isopropylmalate dehydrogenase activity
BJD12_RS18505	COG3852	Histidine kinase
BJD12_RS18515	COG0544	peptidyl-prolyl cis-trans isomerase activity
BJD12_RS18525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BJD12_RS18555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BJD12_RS18565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BJD12_RS18585	COG0631	protein serine/threonine phosphatase activity
BJD12_RS18600	COG0859	PFAM glycosyl transferase family 9
BJD12_RS18610	COG1234	tRNA 3'-trailer cleavage
BJD12_RS18615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BJD12_RS18625	COG0315	cyclic pyranopterin monophosphate synthase activity
BJD12_RS18630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BJD12_RS18635	COG0314	molybdopterin synthase activity
BJD12_RS18645	COG0582	viral genome integration into host DNA
BJD12_RS18675	COG2003	Belongs to the UPF0758 family
BJD12_RS18715	COG3039	Transposase
BJD12_RS18790	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BJD12_RS18800	COG0537	adenosine 5'-monophosphoramidase activity
BJD12_RS18820	COG0714	Associated with various cellular activities
BJD12_RS18840	COG0424	maF-like protein
BJD12_RS18845	COG1399	metal-binding, possibly nucleic acid-binding protein
BJD12_RS18850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BJD12_RS18855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BJD12_RS18865	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS18880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BJD12_RS18885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BJD12_RS18910	COG3829	transcription factor binding
BJD12_RS18955	COG2373	Large extracellular alpha-helical protein
BJD12_RS19000	COG4953	penicillin-binding protein 1C
BJD12_RS19010	COG0678	peroxiredoxin activity
BJD12_RS19030	COG0330	HflC and HflK could
BJD12_RS19035	COG0330	HflC and HflK could
BJD12_RS19040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BJD12_RS19110	COG0732	type I restriction modification DNA specificity domain
BJD12_RS19135	COG1309	transcriptional regulator
BJD12_RS19145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BJD12_RS19155	COG3387	PFAM Glycoside hydrolase 15-related
BJD12_RS19160	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS19170	COG3537	Alpha-1,2-mannosidase
BJD12_RS19230	COG1064	alcohol dehydrogenase
BJD12_RS19235	COG1309	transcriptional regulator
BJD12_RS19240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BJD12_RS19245	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BJD12_RS19250	COG2080	2 iron, 2 sulfur cluster binding
BJD12_RS19275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BJD12_RS19295	COG0587	DNA-directed DNA polymerase activity
BJD12_RS19310	COG1297	OPT oligopeptide transporter protein
BJD12_RS19320	COG1506	peptidase
BJD12_RS19320	COG0823	Involved in the tonB-independent uptake of proteins
BJD12_RS19335	COG1917	Cupin 2, conserved barrel domain protein
BJD12_RS19335	COG2207	Transcriptional regulator
BJD12_RS19345	COG0753	catalase activity
BJD12_RS19350	COG0656	L-ascorbic acid biosynthetic process
BJD12_RS19355	COG2272	Belongs to the type-B carboxylesterase lipase family
BJD12_RS19360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BJD12_RS19360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BJD12_RS19365	COG2814	Major facilitator Superfamily
BJD12_RS19385	COG2194	sulfuric ester hydrolase activity
BJD12_RS19400	COG0745	RESPONSE REGULATOR receiver
BJD12_RS19405	COG5002	protein histidine kinase activity
BJD12_RS19415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BJD12_RS19420	COG2894	cell division
BJD12_RS19435	COG4585	Histidine kinase
BJD12_RS19440	COG2197	response regulator
BJD12_RS19455	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BJD12_RS19485	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BJD12_RS19505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BJD12_RS19525	COG1946	Acyl-CoA thioesterase
BJD12_RS19530	COG1024	Enoyl-CoA hydratase
BJD12_RS19535	COG0824	Thioesterase
BJD12_RS19540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BJD12_RS19550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BJD12_RS19555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BJD12_RS19560	COG0268	Binds directly to 16S ribosomal RNA
BJD12_RS19565	COG0728	peptidoglycan biosynthetic process
BJD12_RS19570	COG0196	riboflavin kinase activity
BJD12_RS19580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BJD12_RS19585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BJD12_RS19600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BJD12_RS19605	COG1845	cytochrome c oxidase, subunit III
BJD12_RS19610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BJD12_RS19625	COG3152	Membrane
BJD12_RS19635	COG2207	Transcriptional regulator
BJD12_RS19640	COG0326	Molecular chaperone. Has ATPase activity
BJD12_RS19650	COG1366	Belongs to the anti-sigma-factor antagonist family
BJD12_RS19655	COG1366	Belongs to the anti-sigma-factor antagonist family
BJD12_RS19660	COG2172	sigma factor antagonist activity
BJD12_RS19680	COG3507	Belongs to the glycosyl hydrolase 43 family
BJD12_RS19685	COG4771	TonB-dependent receptor
BJD12_RS19695	COG5507	3-demethylubiquinone-9 3-methyltransferase
BJD12_RS19710	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BJD12_RS19715	COG3437	response regulator, receiver
BJD12_RS19715	COG3850	Histidine kinase
BJD12_RS19715	COG4999	Histidine kinase
BJD12_RS19715	COG2205	protein histidine kinase activity
BJD12_RS19720	COG4191	Histidine kinase
BJD12_RS19720	COG0784	Response regulator, receiver
BJD12_RS19745	COG3534	alpha-L-arabinofuranosidase
BJD12_RS19760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BJD12_RS19765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BJD12_RS19775	COG2070	2-Nitropropane dioxygenase
BJD12_RS19795	COG0336	Belongs to the RNA methyltransferase TrmD family
BJD12_RS19805	COG0534	Mate efflux family protein
BJD12_RS19815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BJD12_RS19885	COG0840	transmembrane signaling receptor activity
BJD12_RS19905	COG3250	beta-galactosidase activity
BJD12_RS19910	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BJD12_RS19930	COG1960	acyl-CoA dehydrogenase activity
BJD12_RS19935	COG1024	Enoyl-CoA hydratase
BJD12_RS19975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BJD12_RS19980	COG0481	GTPase activity
BJD12_RS20010	COG1381	Involved in DNA repair and RecF pathway recombination
BJD12_RS20020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BJD12_RS20030	COG2954	triphosphatase activity
BJD12_RS20035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BJD12_RS20040	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BJD12_RS20045	COG3046	protein related to deoxyribodipyrimidine photolyase
BJD12_RS20050	COG1472	Belongs to the glycosyl hydrolase 3 family
BJD12_RS20055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BJD12_RS20060	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BJD12_RS20065	COG1278	Cold shock
BJD12_RS20070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BJD12_RS20080	COG1201	RNA secondary structure unwinding
BJD12_RS20085	COG1793	dna ligase
BJD12_RS20095	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BJD12_RS20095	COG1793	dna ligase
BJD12_RS20125	COG0183	Belongs to the thiolase family
BJD12_RS20145	COG1451	nucleotide metabolic process
BJD12_RS20150	COG5487	UPF0391 membrane protein
BJD12_RS20160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BJD12_RS20200	COG1047	Peptidyl-prolyl cis-trans
BJD12_RS20210	COG2824	Alkylphosphonate utilization operon protein PhnA
BJD12_RS20225	COG1902	pentaerythritol trinitrate reductase activity
BJD12_RS20230	COG2814	Major facilitator Superfamily
BJD12_RS20265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BJD12_RS20265	COG0392	lysyltransferase activity
BJD12_RS20275	COG0251	oxidation-reduction process
BJD12_RS20280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BJD12_RS20295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BJD12_RS20320	COG1595	DNA-templated transcription, initiation
BJD12_RS20335	COG2878	Part of a membrane complex involved in electron transport
BJD12_RS20345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJD12_RS20345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BJD12_RS20365	COG0346	lactoylglutathione lyase activity
BJD12_RS20370	COG0833	amino acid
BJD12_RS20375	COG2040	homocysteine
BJD12_RS20385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BJD12_RS20410	COG1695	Transcriptional regulator
BJD12_RS20430	COG1981	membrane
BJD12_RS20440	COG0825	malonyl-CoA metabolic process
BJD12_RS20455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BJD12_RS20460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BJD12_RS20470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BJD12_RS20485	COG0750	zinc metalloprotease
BJD12_RS20490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BJD12_RS20495	COG0575	Belongs to the CDS family
BJD12_RS20510	COG0528	UMP kinase activity
BJD12_RS20520	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BJD12_RS20565	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BJD12_RS20580	COG1393	Belongs to the ArsC family
BJD12_RS20585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BJD12_RS20590	COG0367	asparagine synthase
BJD12_RS20645	COG1566	PFAM secretion protein HlyD family protein
BJD12_RS20650	COG2814	Major facilitator Superfamily
BJD12_RS20705	COG0339	signal peptide processing
BJD12_RS20710	COG0386	Belongs to the glutathione peroxidase family
BJD12_RS20750	COG0288	reversible hydration of carbon dioxide
BJD12_RS20780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BJD12_RS20785	COG0084	hydrolase, TatD family'
BJD12_RS20800	COG1960	acyl-CoA dehydrogenase activity
BJD12_RS20815	COG0367	asparagine synthase
BJD12_RS20825	COG0305	Participates in initiation and elongation during chromosome replication
BJD12_RS20830	COG0415	Belongs to the DNA photolyase family
BJD12_RS20845	COG0583	DNA-binding transcription factor activity
BJD12_RS20860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BJD12_RS20890	COG3706	GGDEF domain
BJD12_RS20910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BJD12_RS20920	COG2914	Belongs to the UPF0125 (RnfH) family
BJD12_RS20925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BJD12_RS20935	COG0497	DNA recombination
BJD12_RS20940	COG1420	regulation of RNA biosynthetic process
BJD12_RS20945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BJD12_RS20960	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BJD12_RS20995	COG1132	(ABC) transporter
BJD12_RS21020	COG0567	Dehydrogenase, E1 component
BJD12_RS21030	COG2850	peptidyl-arginine hydroxylation
BJD12_RS21045	COG1253	flavin adenine dinucleotide binding
BJD12_RS21075	COG1131	(ABC) transporter
BJD12_RS21080	COG1725	Transcriptional regulator
BJD12_RS21090	COG0386	Belongs to the glutathione peroxidase family
BJD12_RS21100	COG2900	Belongs to the SlyX family
BJD12_RS21115	COG1609	Transcriptional regulator
BJD12_RS21125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BJD12_RS21135	COG1410	methionine synthase
BJD12_RS21135	COG0646	methionine synthase
BJD12_RS21140	COG1410	methionine synthase
BJD12_RS21140	COG0646	methionine synthase
BJD12_RS21145	COG2226	methyltransferase
BJD12_RS21150	COG1960	acyl-CoA dehydrogenase activity
BJD12_RS21165	COG0557	exoribonuclease II activity
BJD12_RS21175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BJD12_RS21185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BJD12_RS21205	COG0704	Plays a role in the regulation of phosphate uptake
BJD12_RS21215	COG0581	inorganic phosphate transmembrane transporter activity
BJD12_RS21220	COG0573	inorganic phosphate transmembrane transporter activity
BJD12_RS21225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BJD12_RS21250	COG0659	secondary active sulfate transmembrane transporter activity
BJD12_RS21255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BJD12_RS21265	COG1024	Enoyl-CoA hydratase
BJD12_RS21275	COG0494	nUDIX hydrolase
BJD12_RS21310	COG2264	protein methyltransferase activity
BJD12_RS21320	COG0488	(ABC) transporter
BJD12_RS21360	COG2925	Exonuclease
BJD12_RS21365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BJD12_RS21370	COG3844	kynureninase activity
BJD12_RS21385	COG0288	reversible hydration of carbon dioxide
BJD12_RS21410	COG0017	Asparaginyl-tRNA synthetase
BJD12_RS21415	COG0316	Belongs to the HesB IscA family
BJD12_RS21420	COG0360	Binds together with S18 to 16S ribosomal RNA
BJD12_RS21440	COG3115	cell septum assembly
BJD12_RS21450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BJD12_RS21455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BJD12_RS21490	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BJD12_RS21500	COG4993	Dehydrogenase
BJD12_RS21515	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BJD12_RS21525	COG2986	histidine ammonia-lyase
BJD12_RS21530	COG1228	amidohydrolase
BJD12_RS21570	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BJD12_RS21575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BJD12_RS21580	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BJD12_RS21585	COG1605	Chorismate mutase
BJD12_RS21585	COG0077	Prephenate dehydratase
BJD12_RS21590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BJD12_RS21605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BJD12_RS21610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BJD12_RS21615	COG0583	DNA-binding transcription factor activity
BJD12_RS21690	COG2003	Belongs to the UPF0758 family
BJD12_RS21780	COG0840	transmembrane signaling receptor activity
BJD12_RS21795	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BJD12_RS21800	COG0784	Response regulator, receiver
BJD12_RS21800	COG4191	Histidine kinase
BJD12_RS21815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BJD12_RS21825	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BJD12_RS21835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BJD12_RS21850	COG1595	DNA-templated transcription, initiation
BJD12_RS21890	COG2244	polysaccharide biosynthetic process
BJD12_RS21925	COG4106	trans-aconitate 2-methyltransferase activity
BJD12_RS21935	COG0438	transferase activity, transferring glycosyl groups
BJD12_RS21955	COG1132	(ABC) transporter
BJD12_RS21960	COG0477	Major facilitator Superfamily
BJD12_RS21965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BJD12_RS21980	COG1253	flavin adenine dinucleotide binding
BJD12_RS22000	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BJD12_RS22010	COG2134	cdp-diacylglycerol pyrophosphatase
BJD12_RS22025	COG0504	CTP synthase activity
BJD12_RS22040	COG0148	phosphopyruvate hydratase activity
BJD12_RS22045	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BJD12_RS22055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BJD12_RS22060	COG0585	pseudouridine synthase activity
BJD12_RS22065	COG2840	Smr protein MutS2
BJD12_RS22070	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BJD12_RS22075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BJD12_RS22080	COG1238	metal cluster binding
BJD12_RS22090	COG3737	Protein of unknown function (DUF498/DUF598)
BJD12_RS22095	COG1534	Rna-binding protein
BJD12_RS22100	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BJD12_RS22105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BJD12_RS22110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BJD12_RS22115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BJD12_RS22125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BJD12_RS22130	COG1546	Belongs to the CinA family
BJD12_RS22135	COG4771	TonB-dependent receptor
BJD12_RS22140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BJD12_RS22145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BJD12_RS22150	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BJD12_RS22155	COG2137	regulation of response to DNA damage stimulus
BJD12_RS22160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BJD12_RS22165	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BJD12_RS22180	COG1741	Belongs to the pirin family
BJD12_RS22185	COG0583	DNA-binding transcription factor activity
BJD12_RS22210	COG0351	phosphomethylpyrimidine kinase
BJD12_RS22210	COG0352	thiamine-phosphate diphosphorylase activity
BJD12_RS22225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BJD12_RS22230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BJD12_RS22245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BJD12_RS22255	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BJD12_RS22260	COG3734	2-keto-3-deoxy-galactonokinase
BJD12_RS22270	COG4948	Mandelate Racemase Muconate Lactonizing
BJD12_RS22275	COG0800	Aldolase
BJD12_RS22315	COG1501	Belongs to the glycosyl hydrolase 31 family
BJD12_RS22325	COG1070	Carbohydrate kinase
BJD12_RS22330	COG2115	Belongs to the xylose isomerase family
BJD12_RS22335	COG0477	Major facilitator Superfamily
BJD12_RS22355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BJD12_RS22370	COG0617	tRNA 3'-terminal CCA addition
BJD12_RS22490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BJD12_RS22885	COG1215	transferase activity, transferring glycosyl groups
BJD12_RS22985	COG3210	domain, Protein
BJD12_RS23085	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BJD12_RS23180	COG1028	Short-chain dehydrogenase reductase Sdr
BJD12_RS23265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity