locus-tag	class	description
XBJ1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XBJ1_RS00020	COG0187	DNA topoisomerase II activity
XBJ1_RS00035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XBJ1_RS00055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XBJ1_RS00075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XBJ1_RS00080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XBJ1_RS00085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XBJ1_RS00090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XBJ1_RS00095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XBJ1_RS00100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XBJ1_RS00105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XBJ1_RS00110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XBJ1_RS00120	COG0356	it plays a direct role in the translocation of protons across the membrane
XBJ1_RS00125	COG3312	ion transport
XBJ1_RS00130	COG0357	Ribosomal RNA small subunit methyltransferase G
XBJ1_RS00135	COG0445	tRNA wobble uridine modification
XBJ1_RS00140	COG0716	FMN binding
XBJ1_RS00145	COG1522	sequence-specific DNA binding
XBJ1_RS00150	COG2502	aspartate--ammonia ligase
XBJ1_RS00155	COG2425	protein containing a von Willebrand factor type A (vWA) domain
XBJ1_RS00160	COG0714	Associated with various cellular activities
XBJ1_RS00165	COG1869	D-ribose catabolic process
XBJ1_RS00170	COG1129	ABC transporter
XBJ1_RS00175	COG1172	Belongs to the binding-protein-dependent transport system permease family
XBJ1_RS00180	COG1879	ABC-type sugar transport system periplasmic component
XBJ1_RS00185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_RS00190	COG1609	Transcriptional regulator
XBJ1_RS00195	COG0477	Major facilitator Superfamily
XBJ1_RS00220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBJ1_RS00225	COG3162	membrane
XBJ1_RS00230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XBJ1_RS00235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XBJ1_RS00240	COG0180	Tryptophanyl-tRNA synthetase
XBJ1_RS00245	COG0546	phosphoglycolate phosphatase activity
XBJ1_RS00250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XBJ1_RS00260	COG3266	domain, Protein
XBJ1_RS00265	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
XBJ1_RS00270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XBJ1_RS00275	COG4796	Type ii and iii secretion system protein
XBJ1_RS00295	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XBJ1_RS00300	COG3335	DDE superfamily endonuclease
XBJ1_RS00305	COG0494	nUDIX hydrolase
XBJ1_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
XBJ1_RS00325	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XBJ1_RS00330	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XBJ1_RS00335	COG1741	Belongs to the pirin family
XBJ1_RS00345	COG3335	DDE superfamily endonuclease
XBJ1_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS00375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XBJ1_RS00380	COG3152	Membrane
XBJ1_RS00385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_RS00395	COG2081	HI0933 family
XBJ1_RS00400	COG0306	phosphate transporter
XBJ1_RS00405	COG0589	response to stress
XBJ1_RS00415	COG0742	ribosomal rna small subunit methyltransferase
XBJ1_RS00435	COG3335	DDE superfamily endonuclease
XBJ1_RS00440	COG0366	Alpha amylase catalytic
XBJ1_RS00445	COG1263	PTS System
XBJ1_RS00445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_RS00450	COG1671	Belongs to the UPF0178 family
XBJ1_RS00480	COG1794	racemase activity, acting on amino acids and derivatives
XBJ1_RS00485	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBJ1_RS00510	COG3327	negative regulation of DNA-templated transcription, initiation
XBJ1_RS00515	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
XBJ1_RS00520	COG0183	Belongs to the thiolase family
XBJ1_RS00525	COG2050	protein possibly involved in aromatic compounds catabolism
XBJ1_RS00530	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_RS00535	COG1024	Enoyl-CoA hydratase
XBJ1_RS00540	COG1024	Enoyl-CoA hydratase
XBJ1_RS00545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBJ1_RS00550	COG2151	metal-sulfur cluster biosynthetic enzyme
XBJ1_RS00555	COG3396	Phenylacetate-CoA oxygenase
XBJ1_RS00560	COG3460	Phenylacetate-CoA oxygenase
XBJ1_RS00565	COG3396	Phenylacetate-CoA oxygenase
XBJ1_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS00570	COG2030	dehydratase
XBJ1_RS00575	COG0626	cystathionine gamma-synthase activity
XBJ1_RS00590	COG1735	metal-dependent hydrolase with the TIM-barrel fold
XBJ1_RS00595	COG3457	Alanine racemase
XBJ1_RS00605	COG2188	Transcriptional regulator
XBJ1_RS00615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XBJ1_RS00620	COG1349	DNA-binding transcription factor activity
XBJ1_RS00625	COG0705	Rhomboid family
XBJ1_RS00630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_RS00635	COG0316	Belongs to the HesB IscA family
XBJ1_RS00635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XBJ1_RS00645	COG0596	Alpha beta hydrolase
XBJ1_RS00680	COG0693	protein deglycase activity
XBJ1_RS00705	COG2814	Major facilitator Superfamily
XBJ1_RS00735	COG1918	ferrous iron import across plasma membrane
XBJ1_RS00780	COG3675	Pfam Lipase (class 3)
XBJ1_RS00800	COG2183	response to ionizing radiation
XBJ1_RS00805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBJ1_RS00820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XBJ1_RS00825	COG0573	inorganic phosphate transmembrane transporter activity
XBJ1_RS00830	COG0581	inorganic phosphate transmembrane transporter activity
XBJ1_RS00835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
XBJ1_RS00840	COG0704	Plays a role in the regulation of phosphate uptake
XBJ1_RS00845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_RS00850	COG0765	amino acid transport
XBJ1_RS00855	COG0765	amino acid transport
XBJ1_RS00885	COG2252	PERMEase
XBJ1_RS00905	COG2204	response regulator
XBJ1_RS00955	COG3335	DDE superfamily endonuclease
XBJ1_RS00975	COG1011	Hydrolase
XBJ1_RS00980	COG1490	D-aminoacyl-tRNA deacylase activity
XBJ1_RS00985	COG0456	acetyltransferase
XBJ1_RS00990	COG2982	Protein involved in outer membrane biogenesis
XBJ1_RS00995	COG2233	PERMEase
XBJ1_RS01000	COG0786	glutamate:sodium symporter activity
XBJ1_RS01005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XBJ1_RS01010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XBJ1_RS01015	COG1758	RNA polymerase activity
XBJ1_RS01020	COG0194	GDP metabolic process
XBJ1_RS01025	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XBJ1_RS01030	COG2860	membrane
XBJ1_RS01035	COG0823	Involved in the tonB-independent uptake of proteins
XBJ1_RS01045	COG3335	DDE superfamily endonuclease
XBJ1_RS01050	COG3977	Valine--pyruvate aminotransferase
XBJ1_RS01055	COG2818	Glycosylase
XBJ1_RS01060	COG0752	glycyl-tRNA synthetase alpha subunit
XBJ1_RS01065	COG0751	glycine-tRNA ligase activity
XBJ1_RS01075	COG0747	negative chemotaxis
XBJ1_RS01080	COG0601	transmembrane transport
XBJ1_RS01085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XBJ1_RS01090	COG0444	Belongs to the ABC transporter superfamily
XBJ1_RS01095	COG4608	Belongs to the ABC transporter superfamily
XBJ1_RS01100	COG2199	diguanylate cyclase activity
XBJ1_RS01100	COG2200	EAL domain
XBJ1_RS01105	COG0612	Peptidase, M16
XBJ1_RS01115	COG0477	Major facilitator Superfamily
XBJ1_RS01125	COG1942	4-Oxalocrotonate Tautomerase
XBJ1_RS01130	COG1295	ribonuclease BN
XBJ1_RS01225	COG3501	Rhs element vgr protein
XBJ1_RS01245	COG3209	COG3209 Rhs family protein
XBJ1_RS01260	COG4372	Transposase
XBJ1_RS01265	COG4372	Transposase
XBJ1_RS01285	COG3209	COG3209 Rhs family protein
XBJ1_RS01370	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XBJ1_RS01375	COG0802	atpase or kinase
XBJ1_RS01380	COG0860	N-Acetylmuramoyl-L-alanine amidase
XBJ1_RS01385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XBJ1_RS01390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XBJ1_RS01395	COG1923	regulation of RNA biosynthetic process
XBJ1_RS01400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XBJ1_RS01405	COG0330	HflC and HflK could
XBJ1_RS01410	COG0330	HflC and HflK could
XBJ1_RS01415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XBJ1_RS01420	COG1959	2 iron, 2 sulfur cluster binding
XBJ1_RS01425	COG0557	exoribonuclease II activity
XBJ1_RS01430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XBJ1_RS01435	COG0360	Binds together with S18 to 16S ribosomal RNA
XBJ1_RS01440	COG2965	DNA replication, synthesis of RNA primer
XBJ1_RS01445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XBJ1_RS01455	COG0545	Peptidyl-prolyl cis-trans isomerase
XBJ1_RS01465	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
XBJ1_RS01475	COG1253	flavin adenine dinucleotide binding
XBJ1_RS01480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XBJ1_RS01485	COG0729	surface antigen
XBJ1_RS01490	COG2911	Protein conserved in bacteria
XBJ1_RS01495	COG2105	PFAM AIG2 family protein
XBJ1_RS01505	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XBJ1_RS01510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XBJ1_RS01520	COG0039	L-malate dehydrogenase activity
XBJ1_RS01525	COG3423	Transcriptional regulator
XBJ1_RS01540	COG0142	geranyltranstransferase activity
XBJ1_RS01545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XBJ1_RS01555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XBJ1_RS01560	COG2027	D-alanyl-D-alanine carboxypeptidase
XBJ1_RS01570	COG1534	Rna-binding protein
XBJ1_RS01575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XBJ1_RS01585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XBJ1_RS01590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XBJ1_RS01595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XBJ1_RS01610	COG0779	Required for maturation of 30S ribosomal subunits
XBJ1_RS01615	COG0195	Participates in both transcription termination and antitermination
XBJ1_RS01620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XBJ1_RS01625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XBJ1_RS01630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XBJ1_RS01635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XBJ1_RS01650	COG0513	Belongs to the DEAD box helicase family
XBJ1_RS01660	COG3275	phosphorelay sensor kinase activity
XBJ1_RS01665	COG1388	LysM domain
XBJ1_RS01665	COG4932	domain protein
XBJ1_RS01665	COG2373	Large extracellular alpha-helical protein
XBJ1_RS01670	COG0582	viral genome integration into host DNA
XBJ1_RS01680	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS01695	COG2814	Major facilitator Superfamily
XBJ1_RS01710	COG3154	lipid carrier protein
XBJ1_RS01715	COG3153	acetyltransferase
XBJ1_RS01720	COG2827	Endonuclease containing a URI domain
XBJ1_RS01730	COG3787	Belongs to the UPF0306 family
XBJ1_RS01740	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
XBJ1_RS01750	COG5505	Protein of unknown function (DUF819)
XBJ1_RS01760	COG0540	Belongs to the ATCase OTCase family
XBJ1_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS01805	COG0512	Glutamine amidotransferase of anthranilate synthase
XBJ1_RS01835	COG4650	regulator
XBJ1_RS01845	COG1690	Belongs to the RtcB family
XBJ1_RS01850	COG3541	Predicted nucleotidyltransferase
XBJ1_RS01855	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
XBJ1_RS01860	COG1280	lysine exporter protein (LysE YggA)
XBJ1_RS01880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_RS01885	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
XBJ1_RS01890	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
XBJ1_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_RS01905	COG1126	abc transporter atp-binding protein
XBJ1_RS01910	COG0765	amino acid transport
XBJ1_RS01920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_RS01935	COG2337	Toxic component of a toxin-antitoxin (TA) module
XBJ1_RS01940	COG2336	PFAM SpoVT AbrB
XBJ1_RS01945	COG0525	valine-tRNA ligase activity
XBJ1_RS01950	COG2927	DNA polymerase III (CHI subunit)
XBJ1_RS01955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XBJ1_RS01960	COG0795	lipopolysaccharide-transporting ATPase activity
XBJ1_RS01965	COG0795	lipopolysaccharide-transporting ATPase activity
XBJ1_RS01970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XBJ1_RS01980	COG0582	viral genome integration into host DNA
XBJ1_RS01985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XBJ1_RS02045	COG1177	transmembrane transport
XBJ1_RS02095	COG2873	o-acetylhomoserine
XBJ1_RS02130	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XBJ1_RS02135	COG2363	Small membrane protein
XBJ1_RS02140	COG0583	DNA-binding transcription factor activity
XBJ1_RS02145	COG2252	PERMEase
XBJ1_RS02150	COG0025	NhaP-type Na H and K H
XBJ1_RS02160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XBJ1_RS02165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
XBJ1_RS02175	COG0586	Pfam SNARE associated Golgi protein
XBJ1_RS02180	COG1322	Protein conserved in bacteria
XBJ1_RS02185	COG2226	methyltransferase
XBJ1_RS02190	COG3165	ubiquinone biosynthetic process from chorismate
XBJ1_RS02195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XBJ1_RS02200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XBJ1_RS02205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XBJ1_RS02210	COG0805	protein transport
XBJ1_RS02225	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XBJ1_RS02235	COG0183	Belongs to the thiolase family
XBJ1_RS02240	COG1024	Enoyl-CoA hydratase
XBJ1_RS02240	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_RS02245	COG0006	proline dipeptidase activity
XBJ1_RS02250	COG1739	Uncharacterized protein family UPF0029
XBJ1_RS02260	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
XBJ1_RS02295	COG1914	H( )-stimulated, divalent metal cation uptake system
XBJ1_RS02300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XBJ1_RS02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XBJ1_RS02310	COG4770	biotin carboxylase activity
XBJ1_RS02320	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
XBJ1_RS02330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XBJ1_RS02335	COG1053	succinate dehydrogenase
XBJ1_RS02340	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XBJ1_RS02345	COG0584	glycerophosphoryl diester phosphodiesterase
XBJ1_RS02350	COG2271	Major facilitator Superfamily
XBJ1_RS02365	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XBJ1_RS02370	COG0425	Belongs to the sulfur carrier protein TusA family
XBJ1_RS02380	COG3776	membrane
XBJ1_RS02385	COG0742	ribosomal rna small subunit methyltransferase
XBJ1_RS02390	COG0552	protein localization to endoplasmic reticulum
XBJ1_RS02395	COG2884	Cell division ATP-binding protein ftsE
XBJ1_RS02400	COG2177	Part of the ABC transporter FtsEX involved in
XBJ1_RS02410	COG1929	Belongs to the glycerate kinase type-1 family
XBJ1_RS02415	COG0456	acetyltransferase
XBJ1_RS02425	COG3501	Rhs element vgr protein
XBJ1_RS02475	COG1396	sequence-specific DNA binding
XBJ1_RS02500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBJ1_RS02505	COG1611	Belongs to the LOG family
XBJ1_RS02510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XBJ1_RS02510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XBJ1_RS02520	COG3098	single-species biofilm formation
XBJ1_RS02545	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XBJ1_RS02555	COG0052	Belongs to the universal ribosomal protein uS2 family
XBJ1_RS02560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XBJ1_RS02565	COG0528	UMP kinase activity
XBJ1_RS02570	COG0233	cytoplasmic translational termination
XBJ1_RS02575	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XBJ1_RS02580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XBJ1_RS02585	COG0575	Belongs to the CDS family
XBJ1_RS02590	COG0750	zinc metalloprotease
XBJ1_RS02605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_RS02610	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XBJ1_RS02615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_RS02620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_RS02625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XBJ1_RS02635	COG0825	malonyl-CoA metabolic process
XBJ1_RS02645	COG0037	tRNA processing
XBJ1_RS02650	COG4568	rho-dependent transcription termination
XBJ1_RS02655	COG3015	lipoprotein NlpE involved in copper resistance
XBJ1_RS02660	COG0442	prolyl-tRNA aminoacylation
XBJ1_RS02665	COG1720	tRNA m6t6A37 methyltransferase activity
XBJ1_RS02675	COG1464	Belongs to the NlpA lipoprotein family
XBJ1_RS02685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XBJ1_RS02715	COG2801	Transposase and inactivated derivatives
XBJ1_RS02725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XBJ1_RS02775	COG1304	FMN binding
XBJ1_RS02780	COG3545	Serine hydrolase
XBJ1_RS02810	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS02810	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS02915	COG4695	Portal protein
XBJ1_RS03000	COG0484	heat shock protein binding
XBJ1_RS03030	COG3561	AntA/AntB antirepressor
XBJ1_RS03055	COG0582	viral genome integration into host DNA
XBJ1_RS03075	COG1278	Cold shock
XBJ1_RS03080	COG3397	chitin binding
XBJ1_RS03085	COG0346	lactoylglutathione lyase activity
XBJ1_RS03095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBJ1_RS03100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XBJ1_RS03105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XBJ1_RS03110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_RS03120	COG2205	protein histidine kinase activity
XBJ1_RS03120	COG0784	Response regulator, receiver
XBJ1_RS03125	COG2197	response regulator
XBJ1_RS03130	COG0642	Histidine kinase
XBJ1_RS03130	COG2198	Histidine kinase
XBJ1_RS03145	COG0814	amino acid
XBJ1_RS03160	COG1441	menaquinone biosynthetic process
XBJ1_RS03165	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XBJ1_RS03170	COG0596	Alpha beta hydrolase
XBJ1_RS03175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
XBJ1_RS03185	COG3188	usher protein
XBJ1_RS03190	COG3121	Chaperone
XBJ1_RS03225	COG3335	DDE superfamily endonuclease
XBJ1_RS03230	COG0582	viral genome integration into host DNA
XBJ1_RS03245	COG3335	DDE superfamily endonuclease
XBJ1_RS03250	COG0582	viral genome integration into host DNA
XBJ1_RS03260	COG2920	part of a sulfur-relay system
XBJ1_RS03265	COG1254	Belongs to the acylphosphatase family
XBJ1_RS03270	COG3785	DNA binding
XBJ1_RS03275	COG0210	DNA helicase
XBJ1_RS03280	COG1289	transmembrane transporter activity
XBJ1_RS03300	COG4372	Transposase
XBJ1_RS03325	COG3070	regulator of competence-specific genes
XBJ1_RS03330	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
XBJ1_RS03340	COG3120	sequence-specific DNA binding
XBJ1_RS03345	COG1067	ATP-dependent peptidase activity
XBJ1_RS03355	COG3130	regulation of translation
XBJ1_RS03360	COG3009	Protein conserved in bacteria
XBJ1_RS03365	COG3008	intermembrane lipid transfer
XBJ1_RS03365	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XBJ1_RS03370	COG2995	paraquat-inducible protein a
XBJ1_RS03375	COG0488	(ABC) transporter
XBJ1_RS03380	COG0116	Belongs to the methyltransferase superfamily
XBJ1_RS03380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XBJ1_RS03385	COG0633	Ferredoxin
XBJ1_RS03385	COG3217	Mosc domain protein beta barrel domain protein
XBJ1_RS03395	COG0167	dihydroorotate dehydrogenase activity
XBJ1_RS03400	COG0308	aminopeptidase N
XBJ1_RS03405	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XBJ1_RS03410	COG0017	Asparaginyl-tRNA synthetase
XBJ1_RS03415	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XBJ1_RS03420	COG1448	Aminotransferase
XBJ1_RS03425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBJ1_RS03430	COG3108	Peptidase M15
XBJ1_RS03435	COG2989	Protein conserved in bacteria
XBJ1_RS03440	COG3700	Belongs to the class B bacterial acid phosphatase family
XBJ1_RS03450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XBJ1_RS03455	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
XBJ1_RS03460	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
XBJ1_RS03465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_RS03470	COG1434	Gram-negative-bacterium-type cell wall biogenesis
XBJ1_RS03475	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XBJ1_RS03480	COG2835	tetraacyldisaccharide 4'-kinase activity
XBJ1_RS03485	COG1663	tetraacyldisaccharide 4'-kinase activity
XBJ1_RS03490	COG1132	(ABC) transporter
XBJ1_RS03495	COG0658	competence protein
XBJ1_RS03495	COG2333	competence protein COMEC
XBJ1_RS03505	COG0539	negative regulation of cytoplasmic translation
XBJ1_RS03510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XBJ1_RS03515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBJ1_RS03520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XBJ1_RS03525	COG0252	asparaginase activity
XBJ1_RS03530	COG1944	ATP diphosphatase activity
XBJ1_RS03535	COG2116	formate transmembrane transporter activity
XBJ1_RS03540	COG1882	Formate acetyltransferase
XBJ1_RS03545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
XBJ1_RS03555	COG3335	DDE superfamily endonuclease
XBJ1_RS03575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XBJ1_RS03585	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
XBJ1_RS03590	COG1492	cobalamin metabolic process
XBJ1_RS03655	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
XBJ1_RS03665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XBJ1_RS03675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XBJ1_RS03675	COG1648	precorrin-2 dehydrogenase activity
XBJ1_RS03680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBJ1_RS03690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_RS03695	COG0346	lactoylglutathione lyase activity
XBJ1_RS03715	COG1662	PFAM IS1 transposase
XBJ1_RS03720	COG1846	Transcriptional regulator
XBJ1_RS03725	COG0179	Fumarylacetoacetate (FAA) hydrolase
XBJ1_RS03735	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS03740	COG3384	dioxygenase
XBJ1_RS03755	COG3971	2-oxopent-4-enoate hydratase activity
XBJ1_RS03785	COG0501	Belongs to the peptidase M48B family
XBJ1_RS03790	COG0733	neurotransmitter:sodium symporter activity
XBJ1_RS03805	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XBJ1_RS03810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XBJ1_RS03815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XBJ1_RS03820	COG1674	ftsk spoiiie
XBJ1_RS03820	COG3107	peptidoglycan biosynthetic process
XBJ1_RS03825	COG1522	sequence-specific DNA binding
XBJ1_RS03830	COG0492	ferredoxin-NADP+ reductase activity
XBJ1_RS03840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XBJ1_RS03845	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XBJ1_RS03850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XBJ1_RS03855	COG0542	response to heat
XBJ1_RS03860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XBJ1_RS03865	COG1278	Cold shock
XBJ1_RS03870	COG2431	L-lysine efflux transmembrane transporter activity
XBJ1_RS03875	COG1126	abc transporter atp-binding protein
XBJ1_RS03880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XBJ1_RS03885	COG4215	(ABC) transporter
XBJ1_RS03890	COG4160	amino acid transport
XBJ1_RS03895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBJ1_RS03915	COG0671	phosphoesterase, PA-phosphatase related
XBJ1_RS03920	COG0814	amino acid
XBJ1_RS03925	COG1686	Belongs to the peptidase S11 family
XBJ1_RS03930	COG0625	glutathione transferase activity
XBJ1_RS03935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBJ1_RS03940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XBJ1_RS03945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XBJ1_RS03945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBJ1_RS03950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XBJ1_RS03950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
XBJ1_RS03955	COG0131	Imidazoleglycerol-phosphate dehydratase
XBJ1_RS03955	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XBJ1_RS03960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
XBJ1_RS03965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XBJ1_RS03970	COG0107	imidazoleglycerol-phosphate synthase activity
XBJ1_RS03975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XBJ1_RS03975	COG0140	phosphoribosyl-ATP diphosphatase activity
XBJ1_RS03980	COG1454	alcohol dehydrogenase
XBJ1_RS03990	COG1253	flavin adenine dinucleotide binding
XBJ1_RS04010	COG2982	Protein involved in outer membrane biogenesis
XBJ1_RS04015	COG0717	Belongs to the dCTP deaminase family
XBJ1_RS04020	COG0572	uridine kinase
XBJ1_RS04030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_RS04030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_RS04035	COG1380	Effector of murein hydrolase LrgA
XBJ1_RS04040	COG1346	cytolysis
XBJ1_RS04045	COG0295	cytidine deaminase activity
XBJ1_RS04050	COG0281	malic enzyme
XBJ1_RS04055	COG2949	membrane
XBJ1_RS04060	COG2311	Membrane
XBJ1_RS04065	COG0302	gtp cyclohydrolase
XBJ1_RS04070	COG0477	Major facilitator Superfamily
XBJ1_RS04080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XBJ1_RS04100	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBJ1_RS04105	COG0488	(ABC) transporter
XBJ1_RS04120	COG5006	permease, DMT superfamily
XBJ1_RS04130	COG2824	Alkylphosphonate utilization operon protein PhnA
XBJ1_RS04140	COG2897	thiosulfate sulfurtransferase activity
XBJ1_RS04145	COG2261	transglycosylase associated protein
XBJ1_RS04150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBJ1_RS04155	COG0513	Belongs to the DEAD box helicase family
XBJ1_RS04160	COG1309	transcriptional regulator
XBJ1_RS04170	COG1131	(ABC) transporter
XBJ1_RS04175	COG0842	Transport permease protein
XBJ1_RS04180	COG0842	Transport permease protein
XBJ1_RS04185	COG0670	Belongs to the BI1 family
XBJ1_RS04190	COG0314	molybdopterin synthase activity
XBJ1_RS04195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XBJ1_RS04205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XBJ1_RS04210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
XBJ1_RS04215	COG0556	nucleotide-excision repair
XBJ1_RS04220	COG4974	Belongs to the 'phage' integrase family
XBJ1_RS04280	COG4695	Portal protein
XBJ1_RS04405	COG2226	methyltransferase
XBJ1_RS04410	COG0156	8-amino-7-oxononanoate synthase activity
XBJ1_RS04415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XBJ1_RS04420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
XBJ1_RS04430	COG2706	6-phosphogluconolactonase activity
XBJ1_RS04435	COG0561	phosphatase activity
XBJ1_RS04440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
XBJ1_RS04445	COG4149	molybdate abc transporter
XBJ1_RS04450	COG0725	ABC transporter, periplasmic molybdate-binding protein
XBJ1_RS04455	COG3585	molybdate ion transport
XBJ1_RS04455	COG2005	Transcriptional regulator
XBJ1_RS04460	COG1119	ATPase activity
XBJ1_RS04470	COG0588	phosphoglycerate mutase activity
XBJ1_RS04475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBJ1_RS04495	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
XBJ1_RS04500	COG2885	chlorophyll binding
XBJ1_RS04505	COG0823	Involved in the tonB-independent uptake of proteins
XBJ1_RS04510	COG3064	Membrane
XBJ1_RS04510	COG3064	Membrane
XBJ1_RS04515	COG0848	biopolymer transport protein
XBJ1_RS04520	COG0811	peptide transport
XBJ1_RS04525	COG0824	Thioesterase
XBJ1_RS04530	COG3790	cyd operon protein YbgE
XBJ1_RS04535	COG1294	oxidase, subunit
XBJ1_RS04540	COG1271	oxidase subunit
XBJ1_RS04545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XBJ1_RS04550	COG0045	succinate-CoA ligase (ADP-forming) activity
XBJ1_RS04555	COG0508	dehydrogenase complex catalyzes the overall conversion of
XBJ1_RS04560	COG0567	Dehydrogenase, E1 component
XBJ1_RS04570	COG1053	succinate dehydrogenase
XBJ1_RS04575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XBJ1_RS04595	COG2814	Major facilitator Superfamily
XBJ1_RS04600	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XBJ1_RS04615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XBJ1_RS04620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XBJ1_RS04625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XBJ1_RS04630	COG2205	protein histidine kinase activity
XBJ1_RS04635	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS04645	COG0033	Phosphoglucomutase
XBJ1_RS04650	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
XBJ1_RS04655	COG0596	Alpha beta hydrolase
XBJ1_RS04680	COG3210	domain, Protein
XBJ1_RS04690	COG3501	Rhs element vgr protein
XBJ1_RS04700	COG3064	Membrane
XBJ1_RS04700	COG1073	alpha beta
XBJ1_RS04700	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XBJ1_RS04705	COG2994	toxin metabolic process
XBJ1_RS04730	COG2207	Transcriptional regulator
XBJ1_RS04730	COG0662	Cupin 2, conserved barrel domain protein
XBJ1_RS04735	COG0582	viral genome integration into host DNA
XBJ1_RS04750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBJ1_RS04765	COG0582	viral genome integration into host DNA
XBJ1_RS04785	COG0716	FMN binding
XBJ1_RS04790	COG0735	belongs to the Fur family
XBJ1_RS04800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBJ1_RS04805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBJ1_RS04810	COG2223	nitrite transmembrane transporter activity
XBJ1_RS04815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_RS04820	COG3335	DDE superfamily endonuclease
XBJ1_RS04835	COG2814	Major facilitator Superfamily
XBJ1_RS04840	COG3962	Belongs to the TPP enzyme family
XBJ1_RS04860	COG1309	transcriptional regulator
XBJ1_RS04875	COG1222	aaa ATPase
XBJ1_RS04880	COG0583	DNA-binding transcription factor activity
XBJ1_RS04930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
XBJ1_RS04940	COG1136	(ABC) transporter
XBJ1_RS04970	COG2304	oxidoreductase activity
XBJ1_RS04985	COG2501	S4 domain
XBJ1_RS04990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XBJ1_RS05000	COG0582	viral genome integration into host DNA
XBJ1_RS05140	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_RS05170	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
XBJ1_RS05215	COG3646	Phage regulatory protein
XBJ1_RS05220	COG3335	DDE superfamily endonuclease
XBJ1_RS05230	COG5484	DNA packaging
XBJ1_RS05230	COG3728	DNA packaging
XBJ1_RS05415	COG1484	DNA-dependent DNA replication
XBJ1_RS05420	COG0305	Participates in initiation and elongation during chromosome replication
XBJ1_RS05435	COG2189	Belongs to the N(4) N(6)-methyltransferase family
XBJ1_RS05455	COG3772	lysozyme
XBJ1_RS05480	COG1802	Transcriptional regulator
XBJ1_RS05480	COG4626	Terminase
XBJ1_RS05490	COG4695	Portal protein
XBJ1_RS05595	COG3657	addiction module killer protein
XBJ1_RS05600	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XBJ1_RS05630	COG3209	COG3209 Rhs family protein
XBJ1_RS05645	COG3501	Rhs element vgr protein
XBJ1_RS05650	COG1396	sequence-specific DNA binding
XBJ1_RS05665	COG3209	COG3209 Rhs family protein
XBJ1_RS05680	COG3501	Rhs element vgr protein
XBJ1_RS05805	COG0372	Belongs to the citrate synthase family
XBJ1_RS05830	COG3038	cytochrome b561
XBJ1_RS05835	COG2353	YceI-like domain
XBJ1_RS05870	COG2841	Protein conserved in bacteria
XBJ1_RS05970	COG3772	lysozyme
XBJ1_RS06030	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XBJ1_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS06065	COG0732	type I restriction modification DNA specificity domain
XBJ1_RS06070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
XBJ1_RS06080	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
XBJ1_RS06105	COG0464	growth
XBJ1_RS06115	COG3293	Transposase
XBJ1_RS06150	COG3335	DDE superfamily endonuclease
XBJ1_RS06170	COG3433	isochorismatase activity
XBJ1_RS06170	COG1535	isochorismatase
XBJ1_RS06175	COG1021	2,3-dihydroxybenzoate-AMP ligase
XBJ1_RS06180	COG1169	isochorismate synthase
XBJ1_RS06185	COG4774	siderophore transport
XBJ1_RS06190	COG2382	esterase
XBJ1_RS06195	COG3251	PFAM MbtH domain protein
XBJ1_RS06205	COG1120	ATPase activity
XBJ1_RS06210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_RS06215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_RS06225	COG4592	Periplasmic binding protein
XBJ1_RS06235	COG0010	Belongs to the arginase family
XBJ1_RS06245	COG0583	DNA-binding transcription factor activity
XBJ1_RS06250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XBJ1_RS06255	COG0066	3-isopropylmalate dehydratase activity
XBJ1_RS06265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
XBJ1_RS06270	COG4232	protein-disulfide reductase activity
XBJ1_RS06275	COG1309	transcriptional regulator
XBJ1_RS06285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBJ1_RS06380	COG0515	serine threonine protein kinase
XBJ1_RS06395	COG2204	response regulator
XBJ1_RS06405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBJ1_RS06455	COG3675	Pfam Lipase (class 3)
XBJ1_RS06465	COG5433	transposase activity
XBJ1_RS06515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_RS06610	COG3423	Transcriptional regulator
XBJ1_RS06645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_RS06690	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XBJ1_RS06695	COG4372	Transposase
XBJ1_RS06815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XBJ1_RS06820	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XBJ1_RS06825	COG4181	ATPase activity
XBJ1_RS06830	COG2755	lipolytic protein G-D-S-L family
XBJ1_RS06835	COG0300	oxidoreductase activity
XBJ1_RS06840	COG3118	belongs to the thioredoxin family
XBJ1_RS06845	COG0330	HflC and HflK could
XBJ1_RS06855	COG0789	Transcriptional regulator
XBJ1_RS06860	COG2217	Heavy metal translocating P-type atpase
XBJ1_RS06865	COG3735	TraB family
XBJ1_RS06870	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XBJ1_RS06875	COG0737	Belongs to the 5'-nucleotidase family
XBJ1_RS06880	COG2223	nitrite transmembrane transporter activity
XBJ1_RS06885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XBJ1_RS06885	COG4651	solute:proton antiporter activity
XBJ1_RS06890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_RS06895	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XBJ1_RS06900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XBJ1_RS06905	COG0563	adenylate kinase activity
XBJ1_RS06910	COG0326	Molecular chaperone. Has ATPase activity
XBJ1_RS06915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XBJ1_RS06920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XBJ1_RS06925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XBJ1_RS06930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XBJ1_RS06940	COG1196	nuclear chromosome segregation
XBJ1_RS06940	COG3264	Mechanosensitive ion channel
XBJ1_RS06945	COG1309	transcriptional regulator
XBJ1_RS06950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBJ1_RS06955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBJ1_RS06970	COG0004	ammonium transporteR
XBJ1_RS06975	COG0347	Belongs to the P(II) protein family
XBJ1_RS06980	COG1132	(ABC) transporter
XBJ1_RS06985	COG1132	(ABC) transporter
XBJ1_RS06990	COG1522	sequence-specific DNA binding
XBJ1_RS06995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XBJ1_RS07000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XBJ1_RS07005	COG0824	Thioesterase
XBJ1_RS07010	COG1555	photosystem II stabilization
XBJ1_RS07015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XBJ1_RS07025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XBJ1_RS07030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XBJ1_RS07035	COG0740	serine-type endopeptidase activity
XBJ1_RS07040	COG0544	peptidyl-prolyl cis-trans isomerase activity
XBJ1_RS07050	COG0271	Belongs to the BolA IbaG family
XBJ1_RS07055	COG3056	Lipoprotein
XBJ1_RS07060	COG2223	nitrite transmembrane transporter activity
XBJ1_RS07070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XBJ1_RS07075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XBJ1_RS07080	COG1845	cytochrome c oxidase, subunit III
XBJ1_RS07085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XBJ1_RS07090	COG0109	protoheme IX farnesyltransferase activity
XBJ1_RS07095	COG2814	Major facilitator Superfamily
XBJ1_RS07105	COG1666	GTP binding
XBJ1_RS07110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XBJ1_RS07115	COG0301	tRNA thio-modification
XBJ1_RS07115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_RS07125	COG0142	geranyltranstransferase activity
XBJ1_RS07130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XBJ1_RS07135	COG1509	lysine 2,3-aminomutase activity
XBJ1_RS07165	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
XBJ1_RS07170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
XBJ1_RS07175	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XBJ1_RS07180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XBJ1_RS07185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XBJ1_RS07190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XBJ1_RS07190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XBJ1_RS07195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XBJ1_RS07200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XBJ1_RS07210	COG1862	Preprotein translocase
XBJ1_RS07220	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XBJ1_RS07225	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
XBJ1_RS07230	COG0450	alkyl hydroperoxide reductase
XBJ1_RS07245	COG5002	protein histidine kinase activity
XBJ1_RS07250	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS07255	COG0420	3'-5' exonuclease activity
XBJ1_RS07260	COG0419	ATPase involved in DNA repair
XBJ1_RS07285	COG0737	Belongs to the 5'-nucleotidase family
XBJ1_RS07290	COG0737	Belongs to the 5'-nucleotidase family
XBJ1_RS07300	COG1940	carbohydrate kinase activity
XBJ1_RS07305	COG2974	May be involved in recombination
XBJ1_RS07310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XBJ1_RS07320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XBJ1_RS07340	COG0848	biopolymer transport protein
XBJ1_RS07350	COG0626	cystathionine gamma-synthase activity
XBJ1_RS07360	COG0656	L-ascorbic acid biosynthetic process
XBJ1_RS07370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XBJ1_RS07375	COG0505	Belongs to the CarA family
XBJ1_RS07380	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XBJ1_RS07385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XBJ1_RS07390	COG1047	Peptidyl-prolyl cis-trans
XBJ1_RS07395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XBJ1_RS07400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XBJ1_RS07405	COG0196	riboflavin kinase activity
XBJ1_RS07410	COG0268	Binds directly to 16S ribosomal RNA
XBJ1_RS07415	COG0583	DNA-binding transcription factor activity
XBJ1_RS07420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XBJ1_RS07435	COG2814	Major facilitator Superfamily
XBJ1_RS07450	COG3335	DDE superfamily endonuclease
XBJ1_RS07455	COG0740	serine-type endopeptidase activity
XBJ1_RS07465	COG0484	heat shock protein binding
XBJ1_RS07470	COG0443	Heat shock 70 kDa protein
XBJ1_RS07475	COG1584	GPR1 FUN34 yaaH family protein
XBJ1_RS07480	COG0477	Major facilitator Superfamily
XBJ1_RS07490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBJ1_RS07500	COG1960	acyl-CoA dehydrogenase activity
XBJ1_RS07525	COG0367	asparagine synthase
XBJ1_RS07530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBJ1_RS07580	COG2862	Uncharacterized protein family, UPF0114
XBJ1_RS07595	COG1358	cellular component organization or biogenesis
XBJ1_RS07640	COG0582	viral genome integration into host DNA
XBJ1_RS07655	COG1662	PFAM IS1 transposase
XBJ1_RS07670	COG0417	DNA replication proofreading
XBJ1_RS07675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XBJ1_RS07680	COG0564	pseudouridine synthase activity
XBJ1_RS07685	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XBJ1_RS07690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XBJ1_RS07695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XBJ1_RS07700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
XBJ1_RS07705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XBJ1_RS07710	COG2967	ApaG domain
XBJ1_RS07715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XBJ1_RS07725	COG2132	Multicopper oxidase
XBJ1_RS07730	COG0204	Acyl-transferase
XBJ1_RS07735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XBJ1_RS07745	COG3150	esterase
XBJ1_RS07750	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XBJ1_RS07755	COG0494	nUDIX hydrolase
XBJ1_RS07760	COG1538	Outer membrane efflux protein
XBJ1_RS07765	COG5463	Belongs to the UPF0441 family
XBJ1_RS07770	COG0754	glutathionylspermidine amidase activity
XBJ1_RS07775	COG3384	dioxygenase
XBJ1_RS07785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XBJ1_RS07800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XBJ1_RS07800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XBJ1_RS07805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XBJ1_RS07810	COG3025	triphosphatase activity
XBJ1_RS07815	COG4991	sh3 domain protein
XBJ1_RS07825	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XBJ1_RS07830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XBJ1_RS07835	COG2226	methyltransferase
XBJ1_RS07835	COG2867	negative regulation of translational initiation
XBJ1_RS07840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XBJ1_RS07845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XBJ1_RS07850	COG0358	DNA primase activity
XBJ1_RS07885	COG2003	Belongs to the UPF0758 family
XBJ1_RS07905	COG2378	regulation of single-species biofilm formation
XBJ1_RS07915	COG3596	GTP binding
XBJ1_RS08020	COG3335	DDE superfamily endonuclease
XBJ1_RS08035	COG3385	transposase activity
XBJ1_RS08050	COG5433	transposase activity
XBJ1_RS08085	COG1560	Kdo2-lipid A biosynthetic process
XBJ1_RS08090	COG1054	Belongs to the UPF0176 family
XBJ1_RS08105	COG0418	dihydroorotase activity
XBJ1_RS08165	COG1360	Flagellar Motor Protein
XBJ1_RS08170	COG0643	Histidine kinase
XBJ1_RS08170	COG2198	Histidine kinase
XBJ1_RS08175	COG0835	chemotaxis
XBJ1_RS08180	COG0840	transmembrane signaling receptor activity
XBJ1_RS08185	COG0840	transmembrane signaling receptor activity
XBJ1_RS08190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XBJ1_RS08195	COG2201	protein-glutamate methylesterase activity
XBJ1_RS08200	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS08205	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XBJ1_RS08230	COG1115	amino acid carrier protein
XBJ1_RS08235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XBJ1_RS08255	COG3121	Chaperone
XBJ1_RS08265	COG3539	Fimbrial protein
XBJ1_RS08285	COG1815	bacterial-type flagellum-dependent cell motility
XBJ1_RS08290	COG1558	bacterial-type flagellum-dependent cell motility
XBJ1_RS08315	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
XBJ1_RS08320	COG1706	bacterial-type flagellum-dependent cell motility
XBJ1_RS08335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XBJ1_RS08400	COG3210	domain, Protein
XBJ1_RS08405	COG5433	transposase activity
XBJ1_RS08410	COG3210	domain, Protein
XBJ1_RS08415	COG3547	Transposase (IS116 IS110 IS902 family)
XBJ1_RS08450	COG1403	HNH endonuclease
XBJ1_RS08475	COG1191	sigma factor activity
XBJ1_RS08485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XBJ1_RS08485	COG0506	proline dehydrogenase activity
XBJ1_RS08485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XBJ1_RS08490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XBJ1_RS08570	COG3335	DDE superfamily endonuclease
XBJ1_RS08690	COG0740	serine-type endopeptidase activity
XBJ1_RS08795	COG2239	Acts as a magnesium transporter
XBJ1_RS08805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XBJ1_RS08810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_RS08815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XBJ1_RS08820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XBJ1_RS08850	COG1403	HNH endonuclease
XBJ1_RS09010	COG3104	oligopeptide transport
XBJ1_RS09015	COG2271	Major facilitator Superfamily
XBJ1_RS09020	COG3851	Histidine kinase
XBJ1_RS09025	COG3850	Histidine kinase
XBJ1_RS09030	COG1294	oxidase, subunit
XBJ1_RS09035	COG1271	oxidase subunit
XBJ1_RS09040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XBJ1_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS09060	COG2267	carboxylic ester hydrolase activity
XBJ1_RS09080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XBJ1_RS09095	COG3335	DDE superfamily endonuclease
XBJ1_RS09100	COG2267	carboxylic ester hydrolase activity
XBJ1_RS09140	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBJ1_RS09145	COG2207	Transcriptional regulator
XBJ1_RS09155	COG2226	methyltransferase
XBJ1_RS09160	COG1619	proteins homologs of microcin C7 resistance protein MccF
XBJ1_RS09165	COG0813	purine-nucleoside phosphorylase activity
XBJ1_RS09180	COG0495	leucyl-tRNA aminoacylation
XBJ1_RS09185	COG0442	prolyl-tRNA aminoacylation
XBJ1_RS09220	COG2175	clavaminate synthase activity
XBJ1_RS09225	COG0667	Aldo Keto reductase
XBJ1_RS09240	COG4555	ABC transporter
XBJ1_RS09275	COG0431	NADPH-dependent FMN reductase
XBJ1_RS09295	COG0012	GTP binding
XBJ1_RS09300	COG0193	aminoacyl-tRNA hydrolase activity
XBJ1_RS09315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XBJ1_RS09320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
XBJ1_RS09325	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XBJ1_RS09330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XBJ1_RS09335	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XBJ1_RS09340	COG2890	protein-(glutamine-N5) methyltransferase activity
XBJ1_RS09350	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XBJ1_RS09355	COG0659	secondary active sulfate transmembrane transporter activity
XBJ1_RS09365	COG0671	phosphoesterase, PA-phosphatase related
XBJ1_RS09365	COG2453	phosphatase
XBJ1_RS09370	COG2267	carboxylic ester hydrolase activity
XBJ1_RS09375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XBJ1_RS09380	COG2378	regulation of single-species biofilm formation
XBJ1_RS09400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBJ1_RS09405	COG3381	protein complex oligomerization
XBJ1_RS09415	COG0477	Major facilitator Superfamily
XBJ1_RS09420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_RS09435	COG0018	arginyl-trna synthetase
XBJ1_RS09440	COG3102	Protein conserved in bacteria
XBJ1_RS09445	COG1187	pseudouridine synthase activity
XBJ1_RS09450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBJ1_RS09455	COG1121	(ABC) transporter
XBJ1_RS09460	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
XBJ1_RS09465	COG0739	heme binding
XBJ1_RS09470	COG1560	Kdo2-lipid A biosynthetic process
XBJ1_RS09475	COG0469	pyruvate kinase activity
XBJ1_RS09480	COG1737	Transcriptional regulator
XBJ1_RS09485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XBJ1_RS09490	COG2076	Multidrug Resistance protein
XBJ1_RS09495	COG2076	Multidrug Resistance protein
XBJ1_RS09500	COG0251	oxidation-reduction process
XBJ1_RS09505	COG1199	ATP-dependent helicase activity
XBJ1_RS09515	COG3065	identical protein binding
XBJ1_RS09520	COG0318	PFAM AMP-dependent synthetase and ligase
XBJ1_RS09530	COG1982	Orn Lys Arg decarboxylase major
XBJ1_RS09535	COG0531	amino acid
XBJ1_RS09545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBJ1_RS09550	COG0589	response to stress
XBJ1_RS09565	COG2356	endonuclease I
XBJ1_RS09570	COG3142	Participates in the control of copper homeostasis
XBJ1_RS09575	COG0500	methyltransferase
XBJ1_RS09580	COG2226	methyltransferase
XBJ1_RS09585	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XBJ1_RS09590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XBJ1_RS09595	COG0494	nUDIX hydrolase
XBJ1_RS09600	COG0217	transcriptional regulatory protein
XBJ1_RS09605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XBJ1_RS09610	COG0632	four-way junction helicase activity
XBJ1_RS09615	COG2255	four-way junction helicase activity
XBJ1_RS09620	COG3047	cAMP biosynthetic process
XBJ1_RS09630	COG2823	Periplasmic or secreted lipoprotein
XBJ1_RS09635	COG0159	tryptophan synthase activity
XBJ1_RS09640	COG0133	tryptophan synthase activity
XBJ1_RS09650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XBJ1_RS09670	COG0009	L-threonylcarbamoyladenylate synthase
XBJ1_RS09680	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
XBJ1_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS09690	COG0616	signal peptide processing
XBJ1_RS09725	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
XBJ1_RS09730	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XBJ1_RS09735	COG0284	orotidine-5'-phosphate decarboxylase activity
XBJ1_RS09740	COG0023	Translation Initiation Factor
XBJ1_RS09750	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
XBJ1_RS09755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XBJ1_RS09765	COG4659	FMN binding
XBJ1_RS09785	COG4657	Part of a membrane complex involved in electron transport
XBJ1_RS09795	COG0673	inositol 2-dehydrogenase activity
XBJ1_RS09800	COG0385	Bile acid
XBJ1_RS09805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XBJ1_RS09810	COG5339	Protein conserved in bacteria
XBJ1_RS09815	COG1482	cell wall glycoprotein biosynthetic process
XBJ1_RS09820	COG0114	fumarate hydratase activity
XBJ1_RS09835	COG2814	Major facilitator Superfamily
XBJ1_RS09840	COG0583	DNA-binding transcription factor activity
XBJ1_RS09845	COG1940	carbohydrate kinase activity
XBJ1_RS09850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XBJ1_RS09865	COG4221	oxidoreductase activity
XBJ1_RS09905	COG1846	Transcriptional regulator
XBJ1_RS09910	COG0697	spore germination
XBJ1_RS09920	COG2226	methyltransferase
XBJ1_RS09935	COG2814	Major facilitator Superfamily
XBJ1_RS09950	COG3335	DDE superfamily endonuclease
XBJ1_RS09960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XBJ1_RS09965	COG0589	response to stress
XBJ1_RS09970	COG4974	Belongs to the 'phage' integrase family
XBJ1_RS09975	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XBJ1_RS09980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XBJ1_RS09990	COG0531	amino acid
XBJ1_RS10000	COG3121	Chaperone
XBJ1_RS10020	COG1643	Atp-dependent helicase
XBJ1_RS10025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XBJ1_RS10030	COG3784	Protein of unknown function (DUF1318)
XBJ1_RS10040	COG2911	Protein conserved in bacteria
XBJ1_RS10045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XBJ1_RS10065	COG2983	Belongs to the UPF0260 family
XBJ1_RS10070	COG0179	Fumarylacetoacetate (FAA) hydrolase
XBJ1_RS10075	COG2951	lytic endotransglycosylase activity
XBJ1_RS10080	COG3100	YcgL domain-containing protein
XBJ1_RS10085	COG0850	regulation of cytokinetic process
XBJ1_RS10090	COG2894	cell division
XBJ1_RS10095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XBJ1_RS10100	COG3335	DDE superfamily endonuclease
XBJ1_RS10120	COG2814	Major facilitator Superfamily
XBJ1_RS10125	COG2084	Dehydrogenase
XBJ1_RS10140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XBJ1_RS10150	COG0803	Belongs to the bacterial solute-binding protein 9 family
XBJ1_RS10155	COG1121	(ABC) transporter
XBJ1_RS10160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBJ1_RS10165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XBJ1_RS10170	COG3001	Fructosamine kinase
XBJ1_RS10180	COG3064	Membrane
XBJ1_RS10180	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XBJ1_RS10180	COG1073	alpha beta
XBJ1_RS10190	COG2917	probably involved in intracellular septation
XBJ1_RS10200	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XBJ1_RS10210	COG3099	Belongs to the UPF0263 family
XBJ1_RS10220	COG0444	Belongs to the ABC transporter superfamily
XBJ1_RS10225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XBJ1_RS10230	COG0601	transmembrane transport
XBJ1_RS10255	COG1454	alcohol dehydrogenase
XBJ1_RS10255	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS10260	COG1435	thymidine kinase activity
XBJ1_RS10280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XBJ1_RS10285	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS10290	COG3012	SEC-C Motif Domain Protein
XBJ1_RS10295	COG0788	formyltetrahydrofolate deformylase activity
XBJ1_RS10310	COG0708	Exodeoxyribonuclease III
XBJ1_RS10315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_RS10320	COG0709	Synthesizes selenophosphate from selenide and ATP
XBJ1_RS10325	COG0709	Synthesizes selenophosphate from selenide and ATP
XBJ1_RS10330	COG0778	Nitroreductase
XBJ1_RS10335	COG0616	signal peptide processing
XBJ1_RS10340	COG0252	asparaginase activity
XBJ1_RS10345	COG1335	isochorismatase
XBJ1_RS10350	COG3139	Protein of unknown function (DUF1315)
XBJ1_RS10355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XBJ1_RS10370	COG3713	MltA-interacting MipA family protein
XBJ1_RS10375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XBJ1_RS10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_RS10385	COG2186	Transcriptional regulator
XBJ1_RS10390	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XBJ1_RS10395	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XBJ1_RS10405	COG0037	tRNA processing
XBJ1_RS10410	COG0598	Magnesium transport protein CorA
XBJ1_RS10415	COG4166	transmembrane transport
XBJ1_RS10420	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
XBJ1_RS10435	COG3768	UPF0283 membrane protein
XBJ1_RS10440	COG3106	COG3106 Predicted ATPase
XBJ1_RS10445	COG1983	PspC domain protein
XBJ1_RS10455	COG1842	Phage shock protein A
XBJ1_RS10460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
XBJ1_RS10465	COG4166	transmembrane transport
XBJ1_RS10475	COG4171	peptide transport system, permease
XBJ1_RS10495	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
XBJ1_RS10500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XBJ1_RS10505	COG0259	pyridoxamine-phosphate oxidase activity
XBJ1_RS10510	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XBJ1_RS10515	COG3133	Outer membrane lipoprotein
XBJ1_RS10525	COG0346	lactoylglutathione lyase activity
XBJ1_RS10530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBJ1_RS10535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XBJ1_RS10545	COG1609	Transcriptional regulator
XBJ1_RS10550	COG0583	DNA-binding transcription factor activity
XBJ1_RS10555	COG2814	Major facilitator Superfamily
XBJ1_RS10560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XBJ1_RS10565	COG0307	riboflavin synthase, alpha
XBJ1_RS10570	COG0534	Mate efflux family protein
XBJ1_RS10590	COG4238	major outer membrane lipoprotein
XBJ1_RS10595	COG1388	LysM domain
XBJ1_RS10595	COG1376	ErfK ybiS ycfS ynhG family protein
XBJ1_RS10600	COG2050	protein possibly involved in aromatic compounds catabolism
XBJ1_RS10605	COG0277	FAD linked oxidase domain protein
XBJ1_RS10605	COG0247	lactate metabolic process
XBJ1_RS10610	COG0628	permease
XBJ1_RS10615	COG0574	Belongs to the PEP-utilizing enzyme family
XBJ1_RS10615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XBJ1_RS10620	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XBJ1_RS10625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBJ1_RS10630	COG4771	TonB-dependent receptor
XBJ1_RS10635	COG3720	iron ion transport
XBJ1_RS10640	COG4558	Periplasmic binding protein
XBJ1_RS10645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_RS10650	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XBJ1_RS10665	COG2207	Transcriptional regulator
XBJ1_RS10670	COG0095	Lipoate-protein ligase
XBJ1_RS10675	COG0791	NLP P60 protein
XBJ1_RS10690	COG2076	Multidrug Resistance protein
XBJ1_RS10695	COG2076	Multidrug Resistance protein
XBJ1_RS10700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XBJ1_RS10705	COG0726	polysaccharide deacetylase
XBJ1_RS10710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBJ1_RS10710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XBJ1_RS10715	COG0463	Glycosyl transferase, family 2
XBJ1_RS10720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBJ1_RS10725	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
XBJ1_RS10730	COG4139	cobalamin transport
XBJ1_RS10735	COG0776	regulation of translation
XBJ1_RS10740	COG0072	phenylalanine-tRNA ligase activity
XBJ1_RS10740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XBJ1_RS10755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XBJ1_RS10760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XBJ1_RS10765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XBJ1_RS10770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_RS10775	COG1988	membrane-bound metal-dependent
XBJ1_RS10780	COG1823	symporter activity
XBJ1_RS10785	COG0501	Belongs to the peptidase M48B family
XBJ1_RS10795	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
XBJ1_RS10800	COG1956	GAF domain-containing protein
XBJ1_RS10810	COG1276	copper resistance
XBJ1_RS10815	COG2372	response to copper ion
XBJ1_RS10820	COG1528	Iron-storage protein
XBJ1_RS10835	COG3140	Belongs to the UPF0181 family
XBJ1_RS10845	COG0494	nUDIX hydrolase
XBJ1_RS10850	COG1760	l-serine dehydratase
XBJ1_RS10855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_RS10855	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_RS10860	COG3715	PTS system
XBJ1_RS10865	COG3716	PTS system mannose fructose sorbose family IID component
XBJ1_RS10870	COG4811	Protein of unknown function (DUF986)
XBJ1_RS10875	COG1971	Probably functions as a manganese efflux pump
XBJ1_RS10880	COG2226	methyltransferase
XBJ1_RS10925	COG3335	DDE superfamily endonuclease
XBJ1_RS10930	COG5433	transposase activity
XBJ1_RS10945	COG0519	Catalyzes the synthesis of GMP from XMP
XBJ1_RS10945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XBJ1_RS10950	COG0517	IMP dehydrogenase activity
XBJ1_RS10950	COG0516	GMP reductase activity
XBJ1_RS10955	COG1570	exodeoxyribonuclease VII activity
XBJ1_RS10960	COG1629	transport
XBJ1_RS10960	COG4206	TonB-dependent receptor
XBJ1_RS10965	COG1770	oligopeptidase
XBJ1_RS10985	COG2197	response regulator
XBJ1_RS10990	COG1393	Belongs to the ArsC family
XBJ1_RS10995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XBJ1_RS11000	COG1876	peptidase activity
XBJ1_RS11010	COG1444	tRNA N-acetyltransferase activity
XBJ1_RS11015	COG2707	UPF0756 membrane protein
XBJ1_RS11020	COG3293	Transposase
XBJ1_RS11035	COG5433	transposase activity
XBJ1_RS11045	COG1169	isochorismate synthase
XBJ1_RS11050	COG1021	2,3-dihydroxybenzoate-AMP ligase
XBJ1_RS11055	COG1535	isochorismatase
XBJ1_RS11055	COG3433	isochorismatase activity
XBJ1_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS11065	COG0662	Cupin 2, conserved barrel domain protein
XBJ1_RS11080	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XBJ1_RS11090	COG2233	PERMEase
XBJ1_RS11095	COG3335	DDE superfamily endonuclease
XBJ1_RS11100	COG2233	PERMEase
XBJ1_RS11105	COG3335	DDE superfamily endonuclease
XBJ1_RS11110	COG2233	PERMEase
XBJ1_RS11115	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XBJ1_RS11120	COG1393	Belongs to the ArsC family
XBJ1_RS11125	COG4783	chaperone-mediated protein folding
XBJ1_RS11130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XBJ1_RS11135	COG2716	regulation of RNA biosynthetic process
XBJ1_RS11140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XBJ1_RS11145	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
XBJ1_RS11150	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XBJ1_RS11180	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS11185	COG3778	Protein conserved in bacteria
XBJ1_RS11195	COG4381	Mu-like prophage protein gp46
XBJ1_RS11200	COG4384	Bacteriophage Mu Gp45 protein
XBJ1_RS11265	COG4133	protoheme IX ABC transporter activity
XBJ1_RS11270	COG0582	viral genome integration into host DNA
XBJ1_RS11325	COG0582	viral genome integration into host DNA
XBJ1_RS11345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XBJ1_RS11350	COG0322	excinuclease ABC activity
XBJ1_RS11355	COG2197	response regulator
XBJ1_RS11390	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_RS11420	COG4615	Cyclic peptide transporter
XBJ1_RS11425	COG3321	synthase
XBJ1_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS11425	COG0604	alcohol dehydrogenase
XBJ1_RS11435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBJ1_RS11450	COG1960	acyl-CoA dehydrogenase activity
XBJ1_RS11460	COG1677	Flagellar hook-basal body complex protein FliE
XBJ1_RS11465	COG1766	The M ring may be actively involved in energy transduction
XBJ1_RS11470	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
XBJ1_RS11480	COG1157	protein secretion by the type III secretion system
XBJ1_RS11490	COG3144	bacterial-type flagellum assembly
XBJ1_RS11495	COG1580	Controls the rotational direction of flagella during chemotaxis
XBJ1_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS11580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XBJ1_RS11585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBJ1_RS11590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XBJ1_RS11595	COG2205	protein histidine kinase activity
XBJ1_RS11600	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS11605	COG0826	peptidase U32
XBJ1_RS11610	COG0351	phosphomethylpyrimidine kinase
XBJ1_RS11620	COG1113	amino acid transport
XBJ1_RS11625	COG2207	Transcriptional regulator
XBJ1_RS11630	COG3023	N-Acetylmuramoyl-L-alanine amidase
XBJ1_RS11635	COG1115	amino acid carrier protein
XBJ1_RS11650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XBJ1_RS11660	COG3335	DDE superfamily endonuclease
XBJ1_RS11670	COG0814	amino acid
XBJ1_RS11710	COG3335	DDE superfamily endonuclease
XBJ1_RS11740	COG0583	DNA-binding transcription factor activity
XBJ1_RS11755	COG1113	amino acid transport
XBJ1_RS11770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XBJ1_RS11775	COG0640	Transcriptional regulator
XBJ1_RS11785	COG2801	Transposase and inactivated derivatives
XBJ1_RS11795	COG3385	transposase activity
XBJ1_RS11830	COG3335	DDE superfamily endonuclease
XBJ1_RS11845	COG1605	Chorismate mutase
XBJ1_RS11850	COG3293	Transposase
XBJ1_RS11880	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS11915	COG0582	viral genome integration into host DNA
XBJ1_RS11920	COG0538	isocitrate dehydrogenase activity
XBJ1_RS11925	COG1187	pseudouridine synthase activity
XBJ1_RS11935	COG0482	sulfurtransferase activity
XBJ1_RS11940	COG2915	High frequency lysogenization protein hflD homolog
XBJ1_RS11945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XBJ1_RS11950	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS11955	COG2205	protein histidine kinase activity
XBJ1_RS11960	COG2850	peptidyl-arginine hydroxylation
XBJ1_RS11970	COG4591	ABC-type transport system involved in lipoprotein release permease component
XBJ1_RS11975	COG1136	(ABC) transporter
XBJ1_RS11980	COG4591	ABC-type transport system involved in lipoprotein release permease component
XBJ1_RS11985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XBJ1_RS11995	COG1252	NADH dehydrogenase
XBJ1_RS12000	COG1472	Belongs to the glycosyl hydrolase 3 family
XBJ1_RS12010	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
XBJ1_RS12015	COG0537	adenosine 5'-monophosphoramidase activity
XBJ1_RS12020	COG0084	hydrolase, TatD family'
XBJ1_RS12025	COG0470	DNA polymerase III
XBJ1_RS12030	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XBJ1_RS12035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XBJ1_RS12040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XBJ1_RS12045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBJ1_RS12050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
XBJ1_RS12060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBJ1_RS12065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBJ1_RS12070	COG0416	fatty acid biosynthetic process
XBJ1_RS12075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XBJ1_RS12080	COG1399	metal-binding, possibly nucleic acid-binding protein
XBJ1_RS12085	COG0424	maF-like protein
XBJ1_RS12090	COG0564	pseudouridine synthase activity
XBJ1_RS12095	COG1530	ribonuclease E activity
XBJ1_RS12105	COG2926	Belongs to the UPF0265 family
XBJ1_RS12110	COG2925	Exonuclease
XBJ1_RS12115	COG0277	FAD linked oxidase domain protein
XBJ1_RS12120	COG0531	amino acid
XBJ1_RS12125	COG4771	TonB-dependent receptor
XBJ1_RS12130	COG1120	ATPase activity
XBJ1_RS12135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_RS12145	COG0833	amino acid
XBJ1_RS12150	COG0583	DNA-binding transcription factor activity
XBJ1_RS12155	COG2855	membrane
XBJ1_RS12160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
XBJ1_RS12165	COG1105	Belongs to the carbohydrate kinase PfkB family
XBJ1_RS12170	COG0494	nUDIX hydrolase
XBJ1_RS12180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XBJ1_RS12195	COG0671	phosphoesterase, PA-phosphatase related
XBJ1_RS12200	COG0791	NLP P60 protein
XBJ1_RS12210	COG2814	Major facilitator Superfamily
XBJ1_RS12215	COG1187	pseudouridine synthase activity
XBJ1_RS12220	COG1061	Type III restriction enzyme res subunit
XBJ1_RS12225	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XBJ1_RS12230	COG3081	Nucleoid-associated protein
XBJ1_RS12235	COG3082	Protein of unknown function (DUF1414)
XBJ1_RS12280	COG5433	transposase activity
XBJ1_RS12290	COG1007	ATP synthesis coupled electron transport
XBJ1_RS12295	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_RS12300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XBJ1_RS12305	COG0713	ATP synthesis coupled electron transport
XBJ1_RS12310	COG0839	Belongs to the complex I subunit 6 family
XBJ1_RS12315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_RS12320	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XBJ1_RS12325	COG1034	ATP synthesis coupled electron transport
XBJ1_RS12340	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_RS12340	COG0649	NAD binding
XBJ1_RS12345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_RS12350	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XBJ1_RS12355	COG0583	DNA-binding transcription factor activity
XBJ1_RS12360	COG0436	Aminotransferase
XBJ1_RS12370	COG0471	metal ion transport
XBJ1_RS12370	COG0490	domain, Protein
XBJ1_RS12375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_RS12385	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XBJ1_RS12390	COG0857	belongs to the CobB CobQ family
XBJ1_RS12390	COG0280	phosphate acetyltransferase
XBJ1_RS12395	COG1113	amino acid transport
XBJ1_RS12400	COG2988	succinylglutamate desuccinylase activity
XBJ1_RS12405	COG3724	N-succinylarginine dihydrolase activity
XBJ1_RS12410	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS12415	COG3138	arginine N-succinyltransferase
XBJ1_RS12420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XBJ1_RS12425	COG0488	(ABC) transporter
XBJ1_RS12435	COG1131	(ABC) transporter
XBJ1_RS12445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBJ1_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
XBJ1_RS12460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XBJ1_RS12460	COG2070	2-Nitropropane dioxygenase
XBJ1_RS12485	COG0625	glutathione transferase activity
XBJ1_RS12490	COG1090	epimerase
XBJ1_RS12495	COG0163	prenyltransferase activity
XBJ1_RS12500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XBJ1_RS12505	COG1286	toxin biosynthetic process
XBJ1_RS12510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
XBJ1_RS12515	COG0285	dihydrofolate synthase activity
XBJ1_RS12520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XBJ1_RS12525	COG0586	Pfam SNARE associated Golgi protein
XBJ1_RS12530	COG0101	tRNA pseudouridine synthase activity
XBJ1_RS12535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XBJ1_RS12540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBJ1_RS12555	COG0642	Histidine kinase
XBJ1_RS12570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XBJ1_RS12575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_RS12575	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XBJ1_RS12580	COG0456	acetyltransferase
XBJ1_RS12590	COG3101	peptidyl-lysine hydroxylation
XBJ1_RS12595	COG0730	response to heat
XBJ1_RS12600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XBJ1_RS12615	COG2986	histidine ammonia-lyase
XBJ1_RS12620	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XBJ1_RS12630	COG0010	Belongs to the arginase family
XBJ1_RS12635	COG1228	amidohydrolase
XBJ1_RS12640	COG2840	Smr protein MutS2
XBJ1_RS12645	COG2062	phosphohistidine phosphatase, SixA
XBJ1_RS12650	COG1250	3-hydroxyacyl-CoA dehydrogenase
XBJ1_RS12650	COG1024	Enoyl-CoA hydratase
XBJ1_RS12655	COG0183	Belongs to the thiolase family
XBJ1_RS12660	COG3691	Protein conserved in bacteria
XBJ1_RS12680	COG0408	coproporphyrinogen oxidase activity
XBJ1_RS12695	COG1160	GTP binding
XBJ1_RS12700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBJ1_RS12705	COG2976	Protein conserved in bacteria
XBJ1_RS12710	COG0124	histidyl-tRNA synthetase
XBJ1_RS12715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XBJ1_RS12730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XBJ1_RS12735	COG0105	UTP biosynthetic process
XBJ1_RS12745	COG3655	Transcriptional regulator
XBJ1_RS12755	COG4953	penicillin-binding protein 1C
XBJ1_RS12760	COG2373	Large extracellular alpha-helical protein
XBJ1_RS12770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XBJ1_RS12775	COG2975	iron-sulfur cluster assembly
XBJ1_RS12780	COG0633	Ferredoxin
XBJ1_RS12785	COG0443	Heat shock 70 kDa protein
XBJ1_RS12790	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XBJ1_RS12795	COG0316	Belongs to the HesB IscA family
XBJ1_RS12800	COG0822	iron-sulfur transferase activity
XBJ1_RS12805	COG1104	cysteine desulfurase activity
XBJ1_RS12810	COG1959	2 iron, 2 sulfur cluster binding
XBJ1_RS12815	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XBJ1_RS12825	COG2814	Major facilitator Superfamily
XBJ1_RS12830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XBJ1_RS12835	COG1017	nitric oxide dioxygenase activity
XBJ1_RS12835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XBJ1_RS12840	COG0347	Belongs to the P(II) protein family
XBJ1_RS12845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBJ1_RS12845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XBJ1_RS12850	COG2204	response regulator
XBJ1_RS12855	COG3170	Tfp pilus assembly protein FimV
XBJ1_RS12860	COG2205	protein histidine kinase activity
XBJ1_RS12865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
XBJ1_RS12865	COG0047	phosphoribosylformylglycinamidine synthase activity
XBJ1_RS12870	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
XBJ1_RS12880	COG1418	mRNA catabolic process
XBJ1_RS12885	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XBJ1_RS12925	COG3385	transposase activity
XBJ1_RS12970	COG1388	LysM domain
XBJ1_RS12970	COG0741	lytic transglycosylase activity
XBJ1_RS12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBJ1_RS12980	COG2226	methyltransferase
XBJ1_RS13000	COG2161	toxin-antitoxin pair type II binding
XBJ1_RS13005	COG4115	mRNA cleavage
XBJ1_RS13015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XBJ1_RS13020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XBJ1_RS13050	COG2197	response regulator
XBJ1_RS13055	COG3328	transposase activity
XBJ1_RS13060	COG0215	cysteine-tRNA ligase activity
XBJ1_RS13065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XBJ1_RS13070	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XBJ1_RS13075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XBJ1_RS13080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XBJ1_RS13085	COG0307	riboflavin synthase, alpha
XBJ1_RS13135	COG5433	transposase activity
XBJ1_RS13150	COG3335	DDE superfamily endonuclease
XBJ1_RS13160	COG0727	PFAM Uncharacterised protein family (UPF0153)
XBJ1_RS13200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBJ1_RS13215	COG3530	Putative quorum-sensing-regulated virulence factor
XBJ1_RS13220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBJ1_RS13225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XBJ1_RS13230	COG3115	cell septum assembly
XBJ1_RS13245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_RS13255	COG2190	(PTS) system
XBJ1_RS13265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
XBJ1_RS13270	COG4208	sulfate ABC transporter
XBJ1_RS13275	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XBJ1_RS13295	COG0456	acetyltransferase
XBJ1_RS13320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XBJ1_RS13330	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XBJ1_RS13335	COG1381	Involved in DNA repair and RecF pathway recombination
XBJ1_RS13340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XBJ1_RS13345	COG0571	ribonuclease III activity
XBJ1_RS13355	COG0481	GTPase activity
XBJ1_RS13360	COG3086	response to oxidative stress
XBJ1_RS13375	COG1595	DNA-templated transcription, initiation
XBJ1_RS13380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XBJ1_RS13385	COG0513	Belongs to the DEAD box helicase family
XBJ1_RS13395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XBJ1_RS13400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XBJ1_RS13405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XBJ1_RS13410	COG0497	DNA recombination
XBJ1_RS13415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBJ1_RS13420	COG2914	Belongs to the UPF0125 (RnfH) family
XBJ1_RS13425	COG2867	negative regulation of translational initiation
XBJ1_RS13430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XBJ1_RS13440	COG3335	DDE superfamily endonuclease
XBJ1_RS13460	COG1263	PTS System
XBJ1_RS13460	COG2190	(PTS) system
XBJ1_RS13460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_RS13465	COG0363	glucosamine-6-phosphate deaminase activity
XBJ1_RS13470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XBJ1_RS13475	COG1940	carbohydrate kinase activity
XBJ1_RS13475	COG1846	Transcriptional regulator
XBJ1_RS13535	COG3077	Addiction module antitoxin, RelB DinJ family
XBJ1_RS13560	COG1662	PFAM IS1 transposase
XBJ1_RS13565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBJ1_RS13570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XBJ1_RS13575	COG1702	phosphate starvation-inducible protein PhoH
XBJ1_RS13580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XBJ1_RS13585	COG4535	Mg2 and Co2 transporter CorC
XBJ1_RS13590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XBJ1_RS13600	COG0765	amino acid transport
XBJ1_RS13605	COG0765	amino acid transport
XBJ1_RS13610	COG1126	abc transporter atp-binding protein
XBJ1_RS13615	COG0495	leucyl-tRNA aminoacylation
XBJ1_RS13620	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
XBJ1_RS13625	COG1466	dna polymerase III delta subunit
XBJ1_RS13635	COG0799	negative regulation of ribosome biogenesis
XBJ1_RS13640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
XBJ1_RS13645	COG0768	penicillin binding
XBJ1_RS13650	COG0772	Belongs to the SEDS family
XBJ1_RS13655	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XBJ1_RS13660	COG1686	Belongs to the peptidase S11 family
XBJ1_RS13665	COG2921	Belongs to the UPF0250 family
XBJ1_RS13670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
XBJ1_RS13675	COG0321	lipoyl(octanoyl) transferase activity
XBJ1_RS13680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XBJ1_RS13685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
XBJ1_RS13690	COG1278	Cold shock
XBJ1_RS13695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XBJ1_RS13700	COG4175	Glycine betaine
XBJ1_RS13705	COG4176	ABC-type proline glycine betaine transport system permease component
XBJ1_RS13710	COG2113	Glycine betaine
XBJ1_RS13715	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XBJ1_RS13725	COG1846	Transcriptional regulator
XBJ1_RS13730	COG1566	PFAM secretion protein HlyD family protein
XBJ1_RS13735	COG2814	Major facilitator Superfamily
XBJ1_RS13750	COG3486	L-lysine 6-monooxygenase (NADPH) activity
XBJ1_RS13755	COG4114	ferric iron reductase
XBJ1_RS13760	COG1120	ATPase activity
XBJ1_RS13765	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_RS13770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XBJ1_RS13775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XBJ1_RS13780	COG4773	Receptor
XBJ1_RS13790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XBJ1_RS13795	COG3148	PFAM DTW domain containing protein
XBJ1_RS13800	COG0045	succinate-CoA ligase (ADP-forming) activity
XBJ1_RS13800	COG1042	CoA-binding domain protein
XBJ1_RS13800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XBJ1_RS13805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XBJ1_RS13810	COG5544	Lipoprotein
XBJ1_RS13840	COG0542	response to heat
XBJ1_RS13845	COG1496	oxidoreductase activity
XBJ1_RS13850	COG0564	pseudouridine synthase activity
XBJ1_RS13855	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XBJ1_RS13860	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XBJ1_RS13865	COG1605	Chorismate mutase
XBJ1_RS13865	COG0077	Prephenate dehydratase
XBJ1_RS13870	COG0287	Prephenate dehydrogenase
XBJ1_RS13870	COG1605	Chorismate mutase
XBJ1_RS13875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XBJ1_RS13880	COG0335	large ribosomal subunit rRNA binding
XBJ1_RS13885	COG0336	Belongs to the RNA methyltransferase TrmD family
XBJ1_RS13890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XBJ1_RS13900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XBJ1_RS13905	COG4137	Cytochrome C assembly protein
XBJ1_RS13910	COG4536	flavin adenine dinucleotide binding
XBJ1_RS13940	COG1854	S-ribosylhomocysteine lyase activity
XBJ1_RS13945	COG2918	glutathione biosynthetic process
XBJ1_RS13970	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XBJ1_RS13975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XBJ1_RS13990	COG2814	Major facilitator Superfamily
XBJ1_RS13995	COG0318	PFAM AMP-dependent synthetase and ligase
XBJ1_RS13995	COG0204	Acyl-transferase
XBJ1_RS14005	COG0318	PFAM AMP-dependent synthetase and ligase
XBJ1_RS14005	COG0204	Acyl-transferase
XBJ1_RS14010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XBJ1_RS14015	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XBJ1_RS14020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XBJ1_RS14030	COG1073	alpha beta
XBJ1_RS14035	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XBJ1_RS14045	COG2195	Cleaves the N-terminal amino acid of tripeptides
XBJ1_RS14050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XBJ1_RS14065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
XBJ1_RS14070	COG1309	transcriptional regulator
XBJ1_RS14075	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS14080	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
XBJ1_RS14095	COG1629	transport
XBJ1_RS14110	COG2991	Protein conserved in bacteria
XBJ1_RS14115	COG1477	protein flavinylation
XBJ1_RS14125	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_RS14130	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_RS14135	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_RS14140	COG1805	sodium ion transport
XBJ1_RS14145	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XBJ1_RS14150	COG3034	peptidoglycan biosynthetic process
XBJ1_RS14155	COG5433	transposase activity
XBJ1_RS14160	COG0121	glutamine amidotransferase
XBJ1_RS14165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XBJ1_RS14170	COG1960	acyl-CoA dehydrogenase activity
XBJ1_RS14180	COG0583	DNA-binding transcription factor activity
XBJ1_RS14185	COG0583	DNA-binding transcription factor activity
XBJ1_RS14195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XBJ1_RS14200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XBJ1_RS14205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XBJ1_RS14210	COG0189	ligase activity
XBJ1_RS14215	COG1678	Uncharacterized ACR, COG1678
XBJ1_RS14220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XBJ1_RS14225	COG2805	Type II/IV secretion system protein
XBJ1_RS14230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XBJ1_RS14235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XBJ1_RS14240	COG0762	integral membrane protein
XBJ1_RS14245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XBJ1_RS14250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XBJ1_RS14255	COG4607	ABC-type enterochelin transport system periplasmic component
XBJ1_RS14265	COG2066	Belongs to the glutaminase family
XBJ1_RS14270	COG3171	Protein conserved in bacteria
XBJ1_RS14275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XBJ1_RS14280	COG1194	a g-specific adenine glycosylase
XBJ1_RS14285	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XBJ1_RS14290	COG0741	lytic transglycosylase activity
XBJ1_RS14300	COG5433	transposase activity
XBJ1_RS14345	COG0582	viral genome integration into host DNA
XBJ1_RS14395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XBJ1_RS14430	COG3423	Transcriptional regulator
XBJ1_RS14605	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XBJ1_RS14610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XBJ1_RS14615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XBJ1_RS14620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XBJ1_RS14625	COG4974	Belongs to the 'phage' integrase family
XBJ1_RS14630	COG0716	FMN binding
XBJ1_RS14640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
XBJ1_RS14645	COG0354	folic acid binding
XBJ1_RS14655	COG0477	Major facilitator Superfamily
XBJ1_RS14660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XBJ1_RS14660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XBJ1_RS14665	COG0509	glycine decarboxylation via glycine cleavage system
XBJ1_RS14670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XBJ1_RS14675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBJ1_RS14680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XBJ1_RS14685	COG0006	proline dipeptidase activity
XBJ1_RS14690	COG3079	Belongs to the UPF0149 family
XBJ1_RS14705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XBJ1_RS14710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XBJ1_RS14715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XBJ1_RS14720	COG0583	DNA-binding transcription factor activity
XBJ1_RS14730	COG1279	arginine transmembrane transporter activity
XBJ1_RS14735	COG0668	transmembrane transport
XBJ1_RS14740	COG3112	Uncharacterised protein family (UPF0231)
XBJ1_RS14750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBJ1_RS14755	COG0508	dehydrogenase complex catalyzes the overall conversion of
XBJ1_RS14760	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XBJ1_RS14765	COG2186	Transcriptional regulator
XBJ1_RS14770	COG3725	Membrane protein required for beta-lactamase induction
XBJ1_RS14775	COG3023	N-Acetylmuramoyl-L-alanine amidase
XBJ1_RS14780	COG4969	Belongs to the N-Me-Phe pilin family
XBJ1_RS14785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XBJ1_RS14790	COG1459	type II secretion system
XBJ1_RS14795	COG0237	dephospho-CoA kinase activity
XBJ1_RS14800	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
XBJ1_RS14805	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XBJ1_RS14810	COG0494	nUDIX hydrolase
XBJ1_RS14815	COG0488	(ABC) transporter
XBJ1_RS14820	COG0653	protein targeting
XBJ1_RS14835	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XBJ1_RS14845	COG0849	cell division
XBJ1_RS14850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XBJ1_RS14855	COG1181	Belongs to the D-alanine--D-alanine ligase family
XBJ1_RS14860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XBJ1_RS14865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XBJ1_RS14870	COG0772	Belongs to the SEDS family
XBJ1_RS14875	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
XBJ1_RS14880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XBJ1_RS14885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XBJ1_RS14890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XBJ1_RS14895	COG0768	penicillin binding
XBJ1_RS14900	COG3116	cell division
XBJ1_RS14905	COG0275	rRNA processing
XBJ1_RS14910	COG2001	Belongs to the MraZ family
XBJ1_RS14925	COG0028	Belongs to the TPP enzyme family
XBJ1_RS14930	COG1022	Amp-dependent synthetase and ligase
XBJ1_RS14945	COG0473	3-isopropylmalate dehydrogenase activity
XBJ1_RS14950	COG3066	DNA modification
XBJ1_RS14960	COG0242	peptide deformylase activity
XBJ1_RS14965	COG3335	DDE superfamily endonuclease
XBJ1_RS14970	COG0242	peptide deformylase activity
XBJ1_RS14975	COG0626	cystathionine gamma-synthase activity
XBJ1_RS14995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XBJ1_RS15010	COG0521	Mo-molybdopterin cofactor biosynthetic process
XBJ1_RS15015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XBJ1_RS15020	COG3022	response to hydroperoxide
XBJ1_RS15030	COG0083	homoserine kinase activity
XBJ1_RS15040	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS15045	COG3045	CreA protein
XBJ1_RS15050	COG3708	Transcriptional regulator
XBJ1_RS15050	COG2207	Transcriptional regulator
XBJ1_RS15055	COG0406	alpha-ribazole phosphatase activity
XBJ1_RS15060	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
XBJ1_RS15065	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
XBJ1_RS15070	COG0741	lytic transglycosylase activity
XBJ1_RS15075	COG0488	(ABC) transporter
XBJ1_RS15080	COG1136	(ABC) transporter
XBJ1_RS15080	COG0577	efflux transmembrane transporter activity
XBJ1_RS15090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
XBJ1_RS15095	COG0560	Phosphoserine phosphatase
XBJ1_RS15100	COG3726	membrane protein affecting hemolysin expression
XBJ1_RS15105	COG0582	viral genome integration into host DNA
XBJ1_RS15125	COG3121	Chaperone
XBJ1_RS15130	COG3188	usher protein
XBJ1_RS15135	COG3539	Fimbrial protein
XBJ1_RS15140	COG0813	purine-nucleoside phosphorylase activity
XBJ1_RS15145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
XBJ1_RS15150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
XBJ1_RS15155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
XBJ1_RS15160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XBJ1_RS15165	COG0084	hydrolase, TatD family'
XBJ1_RS15170	COG4667	esterase of the alpha-beta hydrolase superfamily
XBJ1_RS15180	COG2823	Periplasmic or secreted lipoprotein
XBJ1_RS15185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XBJ1_RS15190	COG0456	acetyltransferase
XBJ1_RS15195	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
XBJ1_RS15200	COG2813	Specifically methylates the guanine in position
XBJ1_RS15220	COG1012	belongs to the aldehyde dehydrogenase family
XBJ1_RS15230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XBJ1_RS15245	COG3423	Transcriptional regulator
XBJ1_RS15250	COG2076	Multidrug Resistance protein
XBJ1_RS15265	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XBJ1_RS15270	COG1509	lysine 2,3-aminomutase activity
XBJ1_RS15280	COG0459	protein refolding
XBJ1_RS15295	COG1027	Aspartate ammonia-lyase
XBJ1_RS15305	COG1278	Cold shock
XBJ1_RS15310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XBJ1_RS15320	COG4942	peptidase
XBJ1_RS15320	COG1388	LysM domain
XBJ1_RS15325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XBJ1_RS15330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XBJ1_RS15355	COG1662	PFAM IS1 transposase
XBJ1_RS15370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XBJ1_RS15375	COG2368	4-hydroxyphenylacetate
XBJ1_RS15380	COG0585	pseudouridine synthase activity
XBJ1_RS15385	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XBJ1_RS15390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
XBJ1_RS15400	COG0529	Catalyzes the synthesis of activated sulfate
XBJ1_RS15405	COG2895	sulfate adenylyltransferase (ATP) activity
XBJ1_RS15410	COG0175	sulfate reduction
XBJ1_RS15415	COG1648	precorrin-2 dehydrogenase activity
XBJ1_RS15415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XBJ1_RS15420	COG0175	sulfate reduction
XBJ1_RS15425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XBJ1_RS15430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XBJ1_RS15435	COG0720	synthase
XBJ1_RS15440	COG0602	queuosine metabolic process
XBJ1_RS15450	COG3021	interspecies interaction between organisms
XBJ1_RS15455	COG3012	SEC-C Motif Domain Protein
XBJ1_RS15460	COG0024	Methionine aminopeptidase
XBJ1_RS15465	COG2194	sulfuric ester hydrolase activity
XBJ1_RS15470	COG1966	Carbon starvation protein
XBJ1_RS15475	COG2879	small protein
XBJ1_RS15480	COG0523	cobalamin synthesis protein
XBJ1_RS15485	COG0582	viral genome integration into host DNA
XBJ1_RS15490	COG0814	amino acid
XBJ1_RS15495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBJ1_RS15515	COG0534	Mate efflux family protein
XBJ1_RS15520	COG3842	ATPase activity
XBJ1_RS15530	COG1840	ABC-type Fe3 transport system, periplasmic component
XBJ1_RS15550	COG1166	arginine decarboxylase activity
XBJ1_RS15555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XBJ1_RS15560	COG3091	SprT-like family
XBJ1_RS15575	COG1301	dicarboxylic acid transport
XBJ1_RS15585	COG0471	metal ion transport
XBJ1_RS15590	COG0148	phosphopyruvate hydratase activity
XBJ1_RS15595	COG0504	CTP synthase activity
XBJ1_RS15600	COG3956	TIGRFAM MazG family protein
XBJ1_RS15605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XBJ1_RS15610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBJ1_RS15625	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XBJ1_RS15630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XBJ1_RS15635	COG0316	Belongs to the HesB IscA family
XBJ1_RS15640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XBJ1_RS15650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XBJ1_RS15655	COG1643	Atp-dependent helicase
XBJ1_RS15660	COG1489	DNA binding
XBJ1_RS15670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XBJ1_RS15680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XBJ1_RS15685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XBJ1_RS15690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XBJ1_RS15710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XBJ1_RS15715	COG0842	Transport permease protein
XBJ1_RS15720	COG1131	(ABC) transporter
XBJ1_RS15725	COG0288	reversible hydration of carbon dioxide
XBJ1_RS15740	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
XBJ1_RS15745	COG1178	ABC-type Fe3 transport system permease component
XBJ1_RS15750	COG4143	(ABC) transporter
XBJ1_RS15755	COG0494	nUDIX hydrolase
XBJ1_RS15765	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XBJ1_RS15770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XBJ1_RS15775	COG3335	DDE superfamily endonuclease
XBJ1_RS15785	COG4795	General secretion pathway protein
XBJ1_RS15800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XBJ1_RS15810	COG1074	ATP-dependent DNA helicase activity
XBJ1_RS15815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XBJ1_RS15820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XBJ1_RS15820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XBJ1_RS15825	COG0860	N-Acetylmuramoyl-L-alanine amidase
XBJ1_RS15845	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XBJ1_RS15850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XBJ1_RS15855	COG2166	iron-sulfur cluster assembly
XBJ1_RS15860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XBJ1_RS15865	COG2992	FlgJ-related protein
XBJ1_RS15875	COG1696	Membrane protein involved in D-alanine export
XBJ1_RS15890	COG2610	gluconate transmembrane transporter activity
XBJ1_RS15895	COG3265	gluconokinase activity
XBJ1_RS15900	COG1609	Transcriptional regulator
XBJ1_RS15905	COG1609	Transcriptional regulator
XBJ1_RS15910	COG1486	melibiose metabolic process
XBJ1_RS15915	COG1447	Phosphotransferase system cellobiose-specific component IIA
XBJ1_RS15920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XBJ1_RS15935	COG1309	transcriptional regulator
XBJ1_RS15940	COG2814	Major facilitator Superfamily
XBJ1_RS15965	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBJ1_RS15990	COG1203	CRISPR-associated helicase, Cas3
XBJ1_RS16020	COG1518	maintenance of DNA repeat elements
XBJ1_RS16025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XBJ1_RS16055	COG0583	DNA-binding transcription factor activity
XBJ1_RS16075	COG0367	asparagine synthase
XBJ1_RS16085	COG0367	asparagine synthase
XBJ1_RS16090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XBJ1_RS16140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XBJ1_RS16145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBJ1_RS16150	COG2264	protein methyltransferase activity
XBJ1_RS16155	COG4145	pantothenate transmembrane transporter activity
XBJ1_RS16160	COG3924	membrane
XBJ1_RS16170	COG0439	Biotin carboxylase
XBJ1_RS16175	COG0511	ligase activity, forming carbon-carbon bonds
XBJ1_RS16180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XBJ1_RS16185	COG0604	alcohol dehydrogenase
XBJ1_RS16190	COG1077	Cell shape determining protein MreB Mrl
XBJ1_RS16195	COG1792	Involved in formation and maintenance of cell shape
XBJ1_RS16200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XBJ1_RS16205	COG0424	maF-like protein
XBJ1_RS16215	COG3164	Protein of unknown function
XBJ1_RS16220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XBJ1_RS16225	COG0312	modulator of DNA gyrase
XBJ1_RS16235	COG2732	(Barnase) inhibitor
XBJ1_RS16240	COG3335	DDE superfamily endonuclease
XBJ1_RS16245	COG3028	Belongs to the UPF0307 family
XBJ1_RS16250	COG0312	modulator of DNA gyrase
XBJ1_RS16255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XBJ1_RS16265	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XBJ1_RS16270	COG1660	Displays ATPase and GTPase activities
XBJ1_RS16285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XBJ1_RS16290	COG1137	ATPase activity
XBJ1_RS16295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XBJ1_RS16300	COG3117	lipopolysaccharide transmembrane transporter activity
XBJ1_RS16305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XBJ1_RS16310	COG0517	IMP dehydrogenase activity
XBJ1_RS16310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
XBJ1_RS16315	COG0530	calcium, potassium:sodium antiporter activity
XBJ1_RS16320	COG1127	ABC transporter
XBJ1_RS16325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XBJ1_RS16330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XBJ1_RS16335	COG2854	intermembrane phospholipid transfer
XBJ1_RS16345	COG5007	Belongs to the BolA IbaG family
XBJ1_RS16350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XBJ1_RS16355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XBJ1_RS16360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XBJ1_RS16365	COG3105	Protein conserved in bacteria
XBJ1_RS16370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XBJ1_RS16375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XBJ1_RS16380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XBJ1_RS16385	COG0625	glutathione transferase activity
XBJ1_RS16390	COG2969	positive regulation of protein catabolic process
XBJ1_RS16400	COG0493	'glutamate synthase
XBJ1_RS16405	COG0067	glutamate synthase
XBJ1_RS16405	COG0070	glutamate synthase
XBJ1_RS16405	COG0069	glutamate synthase activity
XBJ1_RS16410	COG0784	Response regulator, receiver
XBJ1_RS16410	COG2198	Histidine kinase
XBJ1_RS16410	COG5002	protein histidine kinase activity
XBJ1_RS16415	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
XBJ1_RS16420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XBJ1_RS16425	COG2823	Periplasmic or secreted lipoprotein
XBJ1_RS16430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XBJ1_RS16435	COG0792	nuclease activity
XBJ1_RS16445	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XBJ1_RS16450	COG1741	Belongs to the pirin family
XBJ1_RS16455	COG0583	DNA-binding transcription factor activity
XBJ1_RS16460	COG2259	Doxx family
XBJ1_RS16475	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
XBJ1_RS16480	COG4575	ribosome binding
XBJ1_RS16485	COG0586	Pfam SNARE associated Golgi protein
XBJ1_RS16490	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
XBJ1_RS16495	COG0446	pyridine nucleotide-disulphide oxidoreductase
XBJ1_RS16495	COG1902	pentaerythritol trinitrate reductase activity
XBJ1_RS16505	COG2990	Protein conserved in bacteria
XBJ1_RS16540	COG2345	Transcriptional regulator
XBJ1_RS16560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XBJ1_RS16565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_RS16600	COG3335	DDE superfamily endonuclease
XBJ1_RS16620	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
XBJ1_RS16625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XBJ1_RS16645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XBJ1_RS16655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XBJ1_RS16665	COG1448	Aminotransferase
XBJ1_RS16720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XBJ1_RS16845	COG4626	Terminase
XBJ1_RS16845	COG1802	Transcriptional regulator
XBJ1_RS16915	COG0484	heat shock protein binding
XBJ1_RS17040	COG0735	belongs to the Fur family
XBJ1_RS17045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XBJ1_RS17050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XBJ1_RS17055	COG2937	Belongs to the GPAT DAPAT family
XBJ1_RS17060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XBJ1_RS17065	COG3161	chorismate lyase activity
XBJ1_RS17070	COG0166	Belongs to the GPI family
XBJ1_RS17075	COG0527	aspartate kinase activity
XBJ1_RS17085	COG0800	Aldolase
XBJ1_RS17095	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XBJ1_RS17100	COG2224	Isocitrate lyase
XBJ1_RS17105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XBJ1_RS17110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
XBJ1_RS17145	COG0138	bifunctional purine biosynthesis protein purh
XBJ1_RS17150	COG0151	Belongs to the GarS family
XBJ1_RS17170	COG1515	deoxyribonuclease V activity
XBJ1_RS17175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XBJ1_RS17180	COG2816	NAD+ diphosphatase activity
XBJ1_RS17190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
XBJ1_RS17195	COG0352	thiamine-phosphate diphosphorylase activity
XBJ1_RS17200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XBJ1_RS17210	COG2022	thiamine diphosphate biosynthetic process
XBJ1_RS17225	COG2223	nitrite transmembrane transporter activity
XBJ1_RS17230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XBJ1_RS17235	COG1064	alcohol dehydrogenase
XBJ1_RS17240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
XBJ1_RS17245	COG2909	trisaccharide binding
XBJ1_RS17255	COG0058	SHG alpha-glucan phosphorylase activity
XBJ1_RS17260	COG1640	4-alpha-glucanotransferase
XBJ1_RS17265	COG3833	ABC-type maltose transport systems, permease component
XBJ1_RS17270	COG1175	transmembrane transport
XBJ1_RS17280	COG3842	ATPase activity
XBJ1_RS17285	COG4580	involved in the transport of maltose and maltodextrins
XBJ1_RS17295	COG0726	polysaccharide deacetylase
XBJ1_RS17300	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XBJ1_RS17305	COG0085	RNA polymerase activity
XBJ1_RS17310	COG0222	ribosome binding
XBJ1_RS17315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XBJ1_RS17320	COG0081	regulation of translation
XBJ1_RS17325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XBJ1_RS17330	COG0250	Participates in transcription elongation, termination and antitermination
XBJ1_RS17345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XBJ1_RS17350	COG0049	tRNA binding
XBJ1_RS17355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XBJ1_RS17360	COG2168	tRNA wobble position uridine thiolation
XBJ1_RS17365	COG2923	Belongs to the DsrF TusC family
XBJ1_RS17370	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
XBJ1_RS17375	COG2964	Protein conserved in bacteria
XBJ1_RS17380	COG0545	Peptidyl-prolyl cis-trans isomerase
XBJ1_RS17385	COG2900	Belongs to the SlyX family
XBJ1_RS17390	COG1047	Peptidyl-prolyl cis-trans
XBJ1_RS17395	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
XBJ1_RS17405	COG2249	NAD(P)H dehydrogenase (quinone) activity
XBJ1_RS17410	COG0488	(ABC) transporter
XBJ1_RS17420	COG0583	DNA-binding transcription factor activity
XBJ1_RS17430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XBJ1_RS17435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XBJ1_RS17435	COG1263	PTS System
XBJ1_RS17445	COG3089	Belongs to the UPF0270 family
XBJ1_RS17450	COG3954	Phosphoribulokinase
XBJ1_RS17465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XBJ1_RS17470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XBJ1_RS17480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBJ1_RS17480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XBJ1_RS17490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XBJ1_RS17495	COG0746	molybdenum cofactor guanylyltransferase activity
XBJ1_RS17500	COG1763	Mo-molybdopterin cofactor biosynthetic process
XBJ1_RS17510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
XBJ1_RS17515	COG1830	Aldolase
XBJ1_RS17525	COG1129	ABC transporter
XBJ1_RS17535	COG2390	Transcriptional regulator
XBJ1_RS17540	COG1070	Carbohydrate kinase
XBJ1_RS17545	COG3550	peptidyl-serine autophosphorylation
XBJ1_RS17550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBJ1_RS17555	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XBJ1_RS17560	COG3423	Transcriptional regulator
XBJ1_RS17565	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS17580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XBJ1_RS17615	COG3264	Mechanosensitive ion channel
XBJ1_RS17615	COG1511	domain protein
XBJ1_RS17620	COG0688	phosphatidylethanolamine metabolic process
XBJ1_RS17625	COG1162	GTPase activity
XBJ1_RS17630	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XBJ1_RS17650	COG0561	phosphatase activity
XBJ1_RS17655	COG2267	carboxylic ester hydrolase activity
XBJ1_RS17660	COG0514	ATP-dependent DNA helicase (RecQ)
XBJ1_RS17665	COG2050	protein possibly involved in aromatic compounds catabolism
XBJ1_RS17680	COG0598	Magnesium transport protein CorA
XBJ1_RS17685	COG0210	DNA helicase
XBJ1_RS17690	COG1011	Hydrolase
XBJ1_RS17700	COG3159	Protein conserved in bacteria
XBJ1_RS17705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XBJ1_RS17715	COG1965	Belongs to the frataxin family
XBJ1_RS17725	COG0181	hydroxymethylbilane synthase activity
XBJ1_RS17735	COG2959	enzyme of heme biosynthesis
XBJ1_RS17740	COG3071	HemY protein
XBJ1_RS17770	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XBJ1_RS17780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XBJ1_RS17785	COG2244	polysaccharide biosynthetic process
XBJ1_RS17790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XBJ1_RS17795	COG0456	acetyltransferase
XBJ1_RS17800	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XBJ1_RS17805	COG1088	dTDP-glucose 4,6-dehydratase activity
XBJ1_RS17810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XBJ1_RS17815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XBJ1_RS17820	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XBJ1_RS17825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XBJ1_RS17830	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XBJ1_RS17835	COG3118	belongs to the thioredoxin family
XBJ1_RS17840	COG0513	Belongs to the DEAD box helicase family
XBJ1_RS17845	COG0248	Ppx GppA phosphatase
XBJ1_RS17850	COG0210	DNA helicase
XBJ1_RS17860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XBJ1_RS17865	COG0583	DNA-binding transcription factor activity
XBJ1_RS17875	COG0129	dihydroxy-acid dehydratase activity
XBJ1_RS17880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XBJ1_RS17885	COG3978	acetolactate synthase activity
XBJ1_RS17900	COG3085	chromosome segregation
XBJ1_RS17905	COG0583	DNA-binding transcription factor activity
XBJ1_RS17945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XBJ1_RS17955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XBJ1_RS17960	COG0009	L-threonylcarbamoyladenylate synthase
XBJ1_RS17965	COG0551	DNA topoisomerase type I activity
XBJ1_RS17970	COG0758	DNA mediated transformation
XBJ1_RS17975	COG0242	peptide deformylase activity
XBJ1_RS17980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XBJ1_RS17985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XBJ1_RS17985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XBJ1_RS17990	COG0569	domain protein
XBJ1_RS17995	COG3036	rescue of stalled ribosome
XBJ1_RS18000	COG0789	Transcriptional regulator
XBJ1_RS18005	COG0203	ribosomal protein L17
XBJ1_RS18010	COG0202	RNA polymerase activity
XBJ1_RS18015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XBJ1_RS18025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XBJ1_RS18030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XBJ1_RS18035	COG0201	protein transport
XBJ1_RS18040	COG0200	Binds to the 23S rRNA
XBJ1_RS18045	COG1841	ribosomal large subunit assembly
XBJ1_RS18050	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XBJ1_RS18055	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XBJ1_RS18060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XBJ1_RS18065	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
XBJ1_RS18070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XBJ1_RS18075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XBJ1_RS18085	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XBJ1_RS18090	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XBJ1_RS18100	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XBJ1_RS18110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XBJ1_RS18115	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XBJ1_RS18120	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XBJ1_RS18125	COG0089	rRNA binding
XBJ1_RS18130	COG0088	Forms part of the polypeptide exit tunnel
XBJ1_RS18135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XBJ1_RS18140	COG0051	transcription antitermination factor activity, RNA binding
XBJ1_RS18185	COG1072	(Pantothenic acid kinase))
XBJ1_RS18195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
XBJ1_RS18230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XBJ1_RS18235	COG4206	TonB-dependent receptor
XBJ1_RS18240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XBJ1_RS18255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XBJ1_RS18265	COG0165	Argininosuccinate lyase
XBJ1_RS18270	COG0137	argininosuccinate synthase activity
XBJ1_RS18275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XBJ1_RS18280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
XBJ1_RS18285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XBJ1_RS18300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XBJ1_RS18305	COG0527	aspartate kinase activity
XBJ1_RS18305	COG0460	homoserine dehydrogenase
XBJ1_RS18310	COG0626	cystathionine gamma-synthase activity
XBJ1_RS18320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XBJ1_RS18325	COG1609	Transcriptional regulator
XBJ1_RS18330	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XBJ1_RS18335	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XBJ1_RS18340	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XBJ1_RS18345	COG1575	Belongs to the MenA family. Type 1 subfamily
XBJ1_RS18350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XBJ1_RS18355	COG3074	FtsZ-dependent cytokinesis
XBJ1_RS18365	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XBJ1_RS18370	COG2814	Major facilitator Superfamily
XBJ1_RS18380	COG3152	Membrane
XBJ1_RS18390	COG0149	triose-phosphate isomerase activity
XBJ1_RS18405	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XBJ1_RS18410	COG0205	6-phosphofructokinase activity
XBJ1_RS18415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
XBJ1_RS18420	COG4589	Belongs to the CDS family
XBJ1_RS18450	COG3678	ATP-independent chaperone mediated protein folding
XBJ1_RS18455	COG0745	RESPONSE REGULATOR receiver
XBJ1_RS18460	COG2205	protein histidine kinase activity
XBJ1_RS18470	COG0673	inositol 2-dehydrogenase activity
XBJ1_RS18490	COG0482	sulfurtransferase activity
XBJ1_RS18520	COG1215	transferase activity, transferring glycosyl groups
XBJ1_RS18530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XBJ1_RS18535	COG1045	serine acetyltransferase
XBJ1_RS18540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XBJ1_RS18545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XBJ1_RS18550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XBJ1_RS18555	COG4942	peptidase
XBJ1_RS18560	COG2861	carbohydrate metabolic process
XBJ1_RS18565	COG1063	alcohol dehydrogenase
XBJ1_RS18570	COG0156	8-amino-7-oxononanoate synthase activity
XBJ1_RS18575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XBJ1_RS18595	COG1216	Glycosyl transferase, family 2
XBJ1_RS18610	COG0859	PFAM glycosyl transferase family 9
XBJ1_RS18620	COG0297	glycogen (starch) synthase activity
XBJ1_RS18620	COG0438	transferase activity, transferring glycosyl groups
XBJ1_RS18625	COG1519	Transferase
XBJ1_RS18635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XBJ1_RS18640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XBJ1_RS18655	COG0438	transferase activity, transferring glycosyl groups
XBJ1_RS18665	COG0438	transferase activity, transferring glycosyl groups
XBJ1_RS18670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XBJ1_RS18680	COG2003	Belongs to the UPF0758 family
XBJ1_RS18685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XBJ1_RS18690	COG0756	dUTP diphosphatase activity
XBJ1_RS18695	COG1309	transcriptional regulator
XBJ1_RS18700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XBJ1_RS18705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XBJ1_RS18710	COG1561	YicC-like family, N-terminal region
XBJ1_RS18775	COG3645	SOS response
XBJ1_RS18800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XBJ1_RS18810	COG2188	Transcriptional regulator
XBJ1_RS18815	COG1368	sulfuric ester hydrolase activity
XBJ1_RS18860	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XBJ1_RS18885	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XBJ1_RS18890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XBJ1_RS18895	COG0706	membrane insertase activity
XBJ1_RS18900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
XBJ1_RS18905	COG0594	ribonuclease P activity
XBJ1_RS18910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XBJ1_RS18960	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS18980	COG1470	cell adhesion involved in biofilm formation
XBJ1_RS18980	COG1388	LysM domain
XBJ1_RS18985	COG1388	LysM domain
XBJ1_RS18985	COG4932	domain protein
XBJ1_RS18985	COG2373	Large extracellular alpha-helical protein
XBJ1_RS19000	COG3209	COG3209 Rhs family protein
XBJ1_RS19010	COG5301	cellulose 1,4-beta-cellobiosidase activity
XBJ1_RS19065	COG2373	Large extracellular alpha-helical protein
XBJ1_RS19065	COG1388	LysM domain
XBJ1_RS19065	COG4932	domain protein
XBJ1_RS19070	COG2313	pseudouridylate synthase activity
XBJ1_RS19105	COG2801	Transposase and inactivated derivatives
XBJ1_RS19155	COG3058	Necessary for formate dehydrogenase activity