locus-tag	class	description
D3790_RS00005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3790_RS00070	COG2226	methyltransferase
D3790_RS00075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3790_RS00080	COG0741	lytic transglycosylase activity
D3790_RS00080	COG1388	LysM domain
D3790_RS00085	COG3842	ATPase activity
D3790_RS00095	COG1177	transmembrane transport
D3790_RS00115	COG3293	Transposase
D3790_RS00180	COG3501	Rhs element vgr protein
D3790_RS00245	COG0346	lactoylglutathione lyase activity
D3790_RS00250	COG3397	chitin binding
D3790_RS00270	COG5433	transposase activity
D3790_RS00290	COG3335	DDE superfamily endonuclease
D3790_RS00455	COG3335	DDE superfamily endonuclease
D3790_RS00465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D3790_RS00475	COG0028	Belongs to the TPP enzyme family
D3790_RS00480	COG2814	Major facilitator Superfamily
D3790_RS00485	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS00495	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
D3790_RS00505	COG2801	Transposase and inactivated derivatives
D3790_RS00530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3790_RS00570	COG3657	addiction module killer protein
D3790_RS00575	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3790_RS00695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3790_RS00725	COG3423	Transcriptional regulator
D3790_RS00850	COG3209	COG3209 Rhs family protein
D3790_RS00850	COG4104	PAAR repeat-containing protein
D3790_RS00870	COG3328	transposase activity
D3790_RS00885	COG0582	viral genome integration into host DNA
D3790_RS00895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D3790_RS00900	COG2501	S4 domain
D3790_RS00920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3790_RS00940	COG0534	Mate efflux family protein
D3790_RS00955	COG3293	Transposase
D3790_RS00985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D3790_RS00990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D3790_RS00995	COG0675	Transposase, IS605 OrfB family
D3790_RS01000	COG2991	Protein conserved in bacteria
D3790_RS01005	COG1477	protein flavinylation
D3790_RS01010	COG2871	sodium ion transport
D3790_RS01015	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D3790_RS01020	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D3790_RS01025	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D3790_RS01030	COG1805	sodium ion transport
D3790_RS01035	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D3790_RS01040	COG3034	peptidoglycan biosynthetic process
D3790_RS01045	COG0121	glutamine amidotransferase
D3790_RS01050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D3790_RS01055	COG1960	acyl-CoA dehydrogenase activity
D3790_RS01065	COG0583	DNA-binding transcription factor activity
D3790_RS01070	COG0583	DNA-binding transcription factor activity
D3790_RS01085	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D3790_RS01090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D3790_RS01095	COG0189	ligase activity
D3790_RS01100	COG1678	Uncharacterized ACR, COG1678
D3790_RS01105	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D3790_RS01110	COG2805	Type II/IV secretion system protein
D3790_RS01115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D3790_RS01120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D3790_RS01125	COG0762	integral membrane protein
D3790_RS01130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D3790_RS01135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D3790_RS01140	COG0066	3-isopropylmalate dehydratase activity
D3790_RS01145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D3790_RS01150	COG0583	DNA-binding transcription factor activity
D3790_RS01160	COG1881	PFAM PEBP family protein
D3790_RS01165	COG4607	ABC-type enterochelin transport system periplasmic component
D3790_RS01175	COG2066	Belongs to the glutaminase family
D3790_RS01180	COG3171	Protein conserved in bacteria
D3790_RS01185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D3790_RS01190	COG1194	a g-specific adenine glycosylase
D3790_RS01195	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
D3790_RS01200	COG0741	lytic transglycosylase activity
D3790_RS01210	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D3790_RS01250	COG2801	Transposase and inactivated derivatives
D3790_RS01285	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D3790_RS01295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D3790_RS01300	COG2801	Transposase and inactivated derivatives
D3790_RS01350	COG3615	Tellurite resistance protein tehB
D3790_RS01350	COG0500	methyltransferase
D3790_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS01370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3790_RS01410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D3790_RS01420	COG1309	transcriptional regulator
D3790_RS01425	COG4232	protein-disulfide reductase activity
D3790_RS01430	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D3790_RS01435	COG1027	Aspartate ammonia-lyase
D3790_RS01450	COG0459	protein refolding
D3790_RS01460	COG1509	lysine 2,3-aminomutase activity
D3790_RS01465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3790_RS01475	COG3423	Transcriptional regulator
D3790_RS01490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3790_RS01500	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS01515	COG2813	Specifically methylates the guanine in position
D3790_RS01520	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
D3790_RS01605	COG3423	Transcriptional regulator
D3790_RS01610	COG3335	DDE superfamily endonuclease
D3790_RS01620	COG3293	Transposase
D3790_RS01635	COG2801	Transposase and inactivated derivatives
D3790_RS01650	COG3547	Transposase (IS116 IS110 IS902 family)
D3790_RS01680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3790_RS01735	COG3501	Rhs element vgr protein
D3790_RS01745	COG3423	Transcriptional regulator
D3790_RS01795	COG4372	Transposase
D3790_RS01800	COG3436	PFAM IS66 Orf2 family protein
D3790_RS01865	COG3962	Belongs to the TPP enzyme family
D3790_RS01870	COG0673	inositol 2-dehydrogenase activity
D3790_RS01875	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3790_RS01880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3790_RS01890	COG3718	enzyme involved in inositol metabolism
D3790_RS01920	COG2862	Uncharacterized protein family, UPF0114
D3790_RS01935	COG1358	cellular component organization or biogenesis
D3790_RS01975	COG5433	transposase activity
D3790_RS02020	COG3335	DDE superfamily endonuclease
D3790_RS02065	COG5433	transposase activity
D3790_RS02070	COG5464	transposase or invertase
D3790_RS02100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D3790_RS02105	COG4208	sulfate ABC transporter
D3790_RS02110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D3790_RS02150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D3790_RS02155	COG2867	negative regulation of translational initiation
D3790_RS02160	COG2914	Belongs to the UPF0125 (RnfH) family
D3790_RS02165	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3790_RS02170	COG0497	DNA recombination
D3790_RS02175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D3790_RS02180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3790_RS02185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D3790_RS02200	COG0513	Belongs to the DEAD box helicase family
D3790_RS02205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D3790_RS02210	COG1595	DNA-templated transcription, initiation
D3790_RS02225	COG3086	response to oxidative stress
D3790_RS02230	COG0481	GTPase activity
D3790_RS02235	COG0681	Belongs to the peptidase S26 family
D3790_RS02240	COG0571	ribonuclease III activity
D3790_RS02250	COG1381	Involved in DNA repair and RecF pathway recombination
D3790_RS02255	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D3790_RS02260	COG0736	holo-[acyl-carrier-protein] synthase activity
D3790_RS02265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D3790_RS02275	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D3790_RS02285	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D3790_RS02290	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D3790_RS02290	COG0047	phosphoribosylformylglycinamidine synthase activity
D3790_RS02295	COG2205	protein histidine kinase activity
D3790_RS02300	COG3170	Tfp pilus assembly protein FimV
D3790_RS02305	COG2204	response regulator
D3790_RS02310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D3790_RS02310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3790_RS02315	COG0347	Belongs to the P(II) protein family
D3790_RS02320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3790_RS02320	COG1017	nitric oxide dioxygenase activity
D3790_RS02325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D3790_RS02330	COG2814	Major facilitator Superfamily
D3790_RS02340	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D3790_RS02345	COG1959	2 iron, 2 sulfur cluster binding
D3790_RS02350	COG1104	cysteine desulfurase activity
D3790_RS02355	COG0822	iron-sulfur transferase activity
D3790_RS02360	COG0316	Belongs to the HesB IscA family
D3790_RS02365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D3790_RS02370	COG0443	Heat shock 70 kDa protein
D3790_RS02375	COG0633	Ferredoxin
D3790_RS02380	COG2975	iron-sulfur cluster assembly
D3790_RS02385	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3790_RS02395	COG2373	Large extracellular alpha-helical protein
D3790_RS02405	COG4953	penicillin-binding protein 1C
D3790_RS02415	COG0105	UTP biosynthetic process
D3790_RS02420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D3790_RS02435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D3790_RS02445	COG0124	histidyl-tRNA synthetase
D3790_RS02450	COG2976	Protein conserved in bacteria
D3790_RS02455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3790_RS02460	COG1160	GTP binding
D3790_RS02480	COG0408	coproporphyrinogen oxidase activity
D3790_RS02490	COG3265	gluconokinase activity
D3790_RS02495	COG2610	gluconate transmembrane transporter activity
D3790_RS02500	COG2026	Addiction module toxin, RelE StbE family
D3790_RS02535	COG2992	FlgJ-related protein
D3790_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS02550	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS02605	COG4974	Belongs to the 'phage' integrase family
D3790_RS02610	COG0358	DNA primase activity
D3790_RS02615	COG1395	domain, Protein
D3790_RS02625	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
D3790_RS02650	COG3501	Rhs element vgr protein
D3790_RS02660	COG5433	transposase activity
D3790_RS02715	COG2841	Protein conserved in bacteria
D3790_RS02720	COG4574	serine-type endopeptidase inhibitor activity
D3790_RS02730	COG3293	Transposase
D3790_RS02760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3790_RS02770	COG2079	MmgE PrpD family protein
D3790_RS02775	COG0372	Belongs to the citrate synthase family
D3790_RS02810	COG1629	transport
D3790_RS02830	COG5433	transposase activity
D3790_RS02845	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
D3790_RS02850	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS02855	COG1309	transcriptional regulator
D3790_RS02860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3790_RS02870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D3790_RS02875	COG2195	Cleaves the N-terminal amino acid of tripeptides
D3790_RS02880	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D3790_RS02885	COG1073	alpha beta
D3790_RS02895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D3790_RS02900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D3790_RS02905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3790_RS02915	COG2814	Major facilitator Superfamily
D3790_RS02925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D3790_RS02930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D3790_RS02935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D3790_RS02960	COG2918	glutathione biosynthetic process
D3790_RS02965	COG1854	S-ribosylhomocysteine lyase activity
D3790_RS02970	COG3328	transposase activity
D3790_RS02975	COG4536	flavin adenine dinucleotide binding
D3790_RS02980	COG4137	Cytochrome C assembly protein
D3790_RS02985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D3790_RS02990	COG0228	four-way junction DNA binding
D3790_RS02995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D3790_RS03000	COG0336	Belongs to the RNA methyltransferase TrmD family
D3790_RS03005	COG0335	large ribosomal subunit rRNA binding
D3790_RS03010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D3790_RS03015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D3790_RS03020	COG1605	Chorismate mutase
D3790_RS03020	COG0287	Prephenate dehydrogenase
D3790_RS03025	COG1605	Chorismate mutase
D3790_RS03025	COG0077	Prephenate dehydratase
D3790_RS03030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3790_RS03035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3790_RS03040	COG0564	pseudouridine synthase activity
D3790_RS03045	COG1496	oxidoreductase activity
D3790_RS03050	COG0542	response to heat
D3790_RS03075	COG5544	Lipoprotein
D3790_RS03080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D3790_RS03085	COG0045	succinate-CoA ligase (ADP-forming) activity
D3790_RS03085	COG1042	CoA-binding domain protein
D3790_RS03085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3790_RS03090	COG3148	PFAM DTW domain containing protein
D3790_RS03095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3790_RS03115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3790_RS03120	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3790_RS03125	COG1120	ATPase activity
D3790_RS03130	COG4114	ferric iron reductase
D3790_RS03135	COG0076	glutamate decarboxylase activity
D3790_RS03140	COG3486	L-lysine 6-monooxygenase (NADPH) activity
D3790_RS03150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3790_RS03155	COG2814	Major facilitator Superfamily
D3790_RS03160	COG1566	PFAM secretion protein HlyD family protein
D3790_RS03165	COG1846	Transcriptional regulator
D3790_RS03175	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D3790_RS03180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3790_RS03185	COG1278	Cold shock
D3790_RS03190	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D3790_RS03195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D3790_RS03200	COG0321	lipoyl(octanoyl) transferase activity
D3790_RS03205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D3790_RS03210	COG2921	Belongs to the UPF0250 family
D3790_RS03215	COG1686	Belongs to the peptidase S11 family
D3790_RS03220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3790_RS03225	COG0772	Belongs to the SEDS family
D3790_RS03230	COG0768	penicillin binding
D3790_RS03235	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D3790_RS03240	COG0799	negative regulation of ribosome biogenesis
D3790_RS03250	COG1466	dna polymerase III delta subunit
D3790_RS03255	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
D3790_RS03260	COG0495	leucyl-tRNA aminoacylation
D3790_RS03265	COG1126	abc transporter atp-binding protein
D3790_RS03270	COG0765	amino acid transport
D3790_RS03275	COG0765	amino acid transport
D3790_RS03285	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D3790_RS03290	COG4535	Mg2 and Co2 transporter CorC
D3790_RS03295	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D3790_RS03300	COG1702	phosphate starvation-inducible protein PhoH
D3790_RS03305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D3790_RS03310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3790_RS03355	COG1940	carbohydrate kinase activity
D3790_RS03355	COG1846	Transcriptional regulator
D3790_RS03360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D3790_RS03365	COG0363	glucosamine-6-phosphate deaminase activity
D3790_RS03370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3790_RS03370	COG2190	(PTS) system
D3790_RS03370	COG1263	PTS System
D3790_RS03380	COG2801	Transposase and inactivated derivatives
D3790_RS03395	COG0716	FMN binding
D3790_RS03400	COG0735	belongs to the Fur family
D3790_RS03410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3790_RS03430	COG0673	inositol 2-dehydrogenase activity
D3790_RS03465	COG2801	Transposase and inactivated derivatives
D3790_RS03510	COG4977	sequence-specific DNA binding
D3790_RS03535	COG2994	toxin metabolic process
D3790_RS03540	COG3064	Membrane
D3790_RS03540	COG1073	alpha beta
D3790_RS03540	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
D3790_RS03555	COG2264	protein methyltransferase activity
D3790_RS03560	COG0596	Alpha beta hydrolase
D3790_RS03565	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
D3790_RS03570	COG0033	Phosphoglucomutase
D3790_RS03580	COG1418	mRNA catabolic process
D3790_RS03585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3790_RS03595	COG0745	RESPONSE REGULATOR receiver
D3790_RS03600	COG2205	protein histidine kinase activity
D3790_RS03605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
D3790_RS03610	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
D3790_RS03615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D3790_RS03630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D3790_RS03640	COG2814	Major facilitator Superfamily
D3790_RS03660	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D3790_RS03665	COG1053	succinate dehydrogenase
D3790_RS03670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3790_RS03675	COG0567	Dehydrogenase, E1 component
D3790_RS03680	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3790_RS03685	COG0045	succinate-CoA ligase (ADP-forming) activity
D3790_RS03690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D3790_RS03695	COG1271	oxidase subunit
D3790_RS03700	COG1294	oxidase, subunit
D3790_RS03705	COG4890	Cyd operon protein YbgT
D3790_RS03710	COG3790	cyd operon protein YbgE
D3790_RS03715	COG0824	Thioesterase
D3790_RS03720	COG0811	peptide transport
D3790_RS03725	COG0848	biopolymer transport protein
D3790_RS03730	COG3064	Membrane
D3790_RS03735	COG0823	Involved in the tonB-independent uptake of proteins
D3790_RS03740	COG2885	chlorophyll binding
D3790_RS03745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D3790_RS03765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D3790_RS03770	COG0588	phosphoglycerate mutase activity
D3790_RS03785	COG1119	ATPase activity
D3790_RS03800	COG0477	Major facilitator Superfamily
D3790_RS03805	COG0725	ABC transporter, periplasmic molybdate-binding protein
D3790_RS03810	COG4149	molybdate abc transporter
D3790_RS03815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D3790_RS03820	COG0561	phosphatase activity
D3790_RS03825	COG2706	6-phosphogluconolactonase activity
D3790_RS03835	COG4106	trans-aconitate 2-methyltransferase activity
D3790_RS03850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D3790_RS03855	COG0156	8-amino-7-oxononanoate synthase activity
D3790_RS03860	COG2226	methyltransferase
D3790_RS03865	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3790_RS03870	COG0556	nucleotide-excision repair
D3790_RS03875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D3790_RS03880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D3790_RS03890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D3790_RS03895	COG0314	molybdopterin synthase activity
D3790_RS03900	COG0670	Belongs to the BI1 family
D3790_RS03910	COG0842	Transport permease protein
D3790_RS03915	COG0842	Transport permease protein
D3790_RS03920	COG1131	(ABC) transporter
D3790_RS03930	COG1309	transcriptional regulator
D3790_RS03935	COG0513	Belongs to the DEAD box helicase family
D3790_RS03940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3790_RS03960	COG3209	COG3209 Rhs family protein
D3790_RS03975	COG4974	Belongs to the 'phage' integrase family
D3790_RS03980	COG0358	DNA primase activity
D3790_RS03985	COG1395	domain, Protein
D3790_RS04015	COG4974	Belongs to the 'phage' integrase family
D3790_RS04020	COG0358	DNA primase activity
D3790_RS04025	COG1395	domain, Protein
D3790_RS04040	COG3209	COG3209 Rhs family protein
D3790_RS04055	COG3501	Rhs element vgr protein
D3790_RS04090	COG3082	Protein of unknown function (DUF1414)
D3790_RS04095	COG3081	Nucleoid-associated protein
D3790_RS04100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D3790_RS04105	COG1061	Type III restriction enzyme res subunit
D3790_RS04110	COG1187	pseudouridine synthase activity
D3790_RS04115	COG2814	Major facilitator Superfamily
D3790_RS04125	COG0791	NLP P60 protein
D3790_RS04130	COG0671	phosphoesterase, PA-phosphatase related
D3790_RS04145	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D3790_RS04150	COG0625	glutathione transferase activity
D3790_RS04155	COG1090	epimerase
D3790_RS04160	COG0163	prenyltransferase activity
D3790_RS04165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D3790_RS04170	COG1286	toxin biosynthetic process
D3790_RS04175	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
D3790_RS04180	COG0285	dihydrofolate synthase activity
D3790_RS04185	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D3790_RS04190	COG0586	Pfam SNARE associated Golgi protein
D3790_RS04195	COG0101	tRNA pseudouridine synthase activity
D3790_RS04200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3790_RS04205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3790_RS04210	COG2207	Transcriptional regulator
D3790_RS04220	COG0642	Histidine kinase
D3790_RS04235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3790_RS04240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3790_RS04240	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D3790_RS04260	COG3101	peptidyl-lysine hydroxylation
D3790_RS04265	COG0730	response to heat
D3790_RS04270	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D3790_RS04285	COG2986	histidine ammonia-lyase
D3790_RS04290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D3790_RS04305	COG0010	Belongs to the arginase family
D3790_RS04310	COG1228	amidohydrolase
D3790_RS04315	COG2840	Smr protein MutS2
D3790_RS04320	COG2062	phosphohistidine phosphatase, SixA
D3790_RS04325	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3790_RS04325	COG1024	Enoyl-CoA hydratase
D3790_RS04330	COG0183	Belongs to the thiolase family
D3790_RS04335	COG3691	Protein conserved in bacteria
D3790_RS04340	COG2067	long-chain fatty acid transport protein
D3790_RS04365	COG0727	PFAM Uncharacterised protein family (UPF0153)
D3790_RS04410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3790_RS04425	COG3530	Putative quorum-sensing-regulated virulence factor
D3790_RS04430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3790_RS04435	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3790_RS04440	COG3115	cell septum assembly
D3790_RS04450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3790_RS04455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3790_RS04465	COG2190	(PTS) system
D3790_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3790_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS04525	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS04530	COG4221	oxidoreductase activity
D3790_RS04535	COG0574	Belongs to the PEP-utilizing enzyme family
D3790_RS04535	COG3848	Pyruvate phosphate dikinase
D3790_RS04540	COG3328	transposase activity
D3790_RS04560	COG3023	N-Acetylmuramoyl-L-alanine amidase
D3790_RS04565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3790_RS04575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D3790_RS04580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3790_RS04590	COG2205	protein histidine kinase activity
D3790_RS04590	COG0784	Response regulator, receiver
D3790_RS04595	COG2197	response regulator
D3790_RS04600	COG2198	Histidine kinase
D3790_RS04600	COG0642	Histidine kinase
D3790_RS04615	COG0814	amino acid
D3790_RS04630	COG1441	menaquinone biosynthetic process
D3790_RS04635	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D3790_RS04640	COG0596	Alpha beta hydrolase
D3790_RS04645	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D3790_RS04655	COG1169	isochorismate synthase
D3790_RS04660	COG0457	Tetratricopeptide repeat
D3790_RS04665	COG1649	PFAM Uncharacterised BCR, COG1649
D3790_RS04665	COG0726	polysaccharide deacetylase
D3790_RS04670	COG1215	transferase activity, transferring glycosyl groups
D3790_RS04685	COG2199	diguanylate cyclase activity
D3790_RS04690	COG2885	chlorophyll binding
D3790_RS04695	COG2200	EAL domain
D3790_RS04695	COG2771	luxR family
D3790_RS04725	COG3037	sugar-specific permease SgaT UlaA
D3790_RS04735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3790_RS04740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3790_RS04750	COG1007	ATP synthesis coupled electron transport
D3790_RS04755	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3790_RS04760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D3790_RS04765	COG0713	ATP synthesis coupled electron transport
D3790_RS04770	COG0839	Belongs to the complex I subunit 6 family
D3790_RS04775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3790_RS04785	COG1034	ATP synthesis coupled electron transport
D3790_RS04790	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D3790_RS04800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3790_RS04800	COG0649	NAD binding
D3790_RS04805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3790_RS04810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D3790_RS04820	COG0583	DNA-binding transcription factor activity
D3790_RS04825	COG0436	Aminotransferase
D3790_RS04835	COG0471	metal ion transport
D3790_RS04835	COG0490	domain, Protein
D3790_RS04840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3790_RS04845	COG3092	negative regulation of chromosome organization
D3790_RS04850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D3790_RS04855	COG0280	phosphate acetyltransferase
D3790_RS04855	COG0857	belongs to the CobB CobQ family
D3790_RS04915	COG5433	transposase activity
D3790_RS04925	COG4615	Cyclic peptide transporter
D3790_RS04985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D3790_RS04995	COG1105	Belongs to the carbohydrate kinase PfkB family
D3790_RS05000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D3790_RS05005	COG2855	membrane
D3790_RS05010	COG0583	DNA-binding transcription factor activity
D3790_RS05015	COG0833	amino acid
D3790_RS05025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3790_RS05030	COG1120	ATPase activity
D3790_RS05035	COG4771	TonB-dependent receptor
D3790_RS05045	COG0531	amino acid
D3790_RS05050	COG0277	FAD linked oxidase domain protein
D3790_RS05055	COG2925	Exonuclease
D3790_RS05060	COG2926	Belongs to the UPF0265 family
D3790_RS05075	COG5441	Belongs to the UPF0261 family
D3790_RS05080	COG5564	TIM-barrel signal transduction protein
D3790_RS05090	COG0702	epimerase
D3790_RS05100	COG1530	ribonuclease E activity
D3790_RS05110	COG0564	pseudouridine synthase activity
D3790_RS05115	COG0424	maF-like protein
D3790_RS05120	COG1399	metal-binding, possibly nucleic acid-binding protein
D3790_RS05125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D3790_RS05130	COG0416	fatty acid biosynthetic process
D3790_RS05135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3790_RS05140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D3790_RS05150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D3790_RS05155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D3790_RS05160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3790_RS05165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D3790_RS05170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D3790_RS05175	COG0470	DNA polymerase III
D3790_RS05180	COG0084	hydrolase, TatD family'
D3790_RS05185	COG0537	adenosine 5'-monophosphoramidase activity
D3790_RS05190	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
D3790_RS05200	COG1472	Belongs to the glycosyl hydrolase 3 family
D3790_RS05205	COG1252	NADH dehydrogenase
D3790_RS05210	COG3134	Outer membrane lipoprotein
D3790_RS05215	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D3790_RS05220	COG4591	ABC-type transport system involved in lipoprotein release permease component
D3790_RS05225	COG1136	(ABC) transporter
D3790_RS05230	COG4591	ABC-type transport system involved in lipoprotein release permease component
D3790_RS05260	COG2850	peptidyl-arginine hydroxylation
D3790_RS05270	COG0745	RESPONSE REGULATOR receiver
D3790_RS05275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D3790_RS05280	COG2915	High frequency lysogenization protein hflD homolog
D3790_RS05285	COG0482	sulfurtransferase activity
D3790_RS05295	COG1187	pseudouridine synthase activity
D3790_RS05300	COG0538	isocitrate dehydrogenase activity
D3790_RS05330	COG1115	amino acid carrier protein
D3790_RS05335	COG3023	N-Acetylmuramoyl-L-alanine amidase
D3790_RS05340	COG3708	Transcriptional regulator
D3790_RS05340	COG2207	Transcriptional regulator
D3790_RS05360	COG0351	phosphomethylpyrimidine kinase
D3790_RS05365	COG1830	Aldolase
D3790_RS05370	COG0826	peptidase U32
D3790_RS05375	COG2814	Major facilitator Superfamily
D3790_RS05380	COG0745	RESPONSE REGULATOR receiver
D3790_RS05385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3790_RS05390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3790_RS05395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3790_RS05405	COG2239	Acts as a magnesium transporter
D3790_RS05415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D3790_RS05420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3790_RS05425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D3790_RS05430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D3790_RS05435	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D3790_RS05440	COG2233	PERMEase
D3790_RS05445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D3790_RS05450	COG1393	Belongs to the ArsC family
D3790_RS05455	COG4783	chaperone-mediated protein folding
D3790_RS05460	COG0628	permease
D3790_RS05465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D3790_RS05470	COG2716	regulation of RNA biosynthetic process
D3790_RS05475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D3790_RS05480	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
D3790_RS05485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D3790_RS05500	COG2707	UPF0756 membrane protein
D3790_RS05505	COG1444	tRNA N-acetyltransferase activity
D3790_RS05515	COG1876	peptidase activity
D3790_RS05520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3790_RS05525	COG1393	Belongs to the ArsC family
D3790_RS05530	COG2197	response regulator
D3790_RS05550	COG1770	oligopeptidase
D3790_RS05600	COG4171	peptide transport system, permease
D3790_RS05610	COG4166	transmembrane transport
D3790_RS05615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D3790_RS05620	COG1842	Phage shock protein A
D3790_RS05630	COG1983	PspC domain protein
D3790_RS05635	COG3106	COG3106 Predicted ATPase
D3790_RS05655	COG0598	Magnesium transport protein CorA
D3790_RS05660	COG0037	tRNA processing
D3790_RS05675	COG3423	Transcriptional regulator
D3790_RS05685	COG1113	amino acid transport
D3790_RS05710	COG0456	acetyltransferase
D3790_RS05710	COG1214	PFAM Peptidase M22, glycoprotease
D3790_RS05715	COG2169	Transcriptional regulator
D3790_RS05715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D3790_RS05735	COG2197	response regulator
D3790_RS05740	COG0322	excinuclease ABC activity
D3790_RS05745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D3790_RS05765	COG0582	viral genome integration into host DNA
D3790_RS05840	COG3111	PFAM Bacterial OB fold (BOF) protein
D3790_RS05880	COG3328	transposase activity
D3790_RS05920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D3790_RS05925	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D3790_RS05930	COG2186	Transcriptional regulator
D3790_RS06075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3790_RS06080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D3790_RS06095	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3790_RS06100	COG3139	Protein of unknown function (DUF1315)
D3790_RS06120	COG1335	isochorismatase
D3790_RS06125	COG0252	asparaginase activity
D3790_RS06135	COG0616	signal peptide processing
D3790_RS06140	COG0778	Nitroreductase
D3790_RS06145	COG0709	Synthesizes selenophosphate from selenide and ATP
D3790_RS06150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D3790_RS06175	COG0788	formyltetrahydrofolate deformylase activity
D3790_RS06180	COG3012	SEC-C Motif Domain Protein
D3790_RS06185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D3790_RS06205	COG1435	thymidine kinase activity
D3790_RS06210	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS06210	COG1454	alcohol dehydrogenase
D3790_RS06215	COG2095	MarC family integral membrane protein
D3790_RS06235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3790_RS06240	COG0444	Belongs to the ABC transporter superfamily
D3790_RS06245	COG4608	Belongs to the ABC transporter superfamily
D3790_RS06265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D3790_RS06330	COG3099	Belongs to the UPF0263 family
D3790_RS06355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
D3790_RS06375	COG2917	probably involved in intracellular septation
D3790_RS06390	COG3047	cAMP biosynthetic process
D3790_RS06395	COG0159	tryptophan synthase activity
D3790_RS06400	COG0133	tryptophan synthase activity
D3790_RS06410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D3790_RS06440	COG0009	L-threonylcarbamoyladenylate synthase
D3790_RS06455	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS06460	COG0616	signal peptide processing
D3790_RS06475	COG0583	DNA-binding transcription factor activity
D3790_RS06485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D3790_RS06500	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
D3790_RS06505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D3790_RS06510	COG0284	orotidine-5'-phosphate decarboxylase activity
D3790_RS06515	COG0023	Translation Initiation Factor
D3790_RS06535	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
D3790_RS06575	COG2801	Transposase and inactivated derivatives
D3790_RS06580	COG3328	transposase activity
D3790_RS06590	COG2801	Transposase and inactivated derivatives
D3790_RS06615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D3790_RS06625	COG4659	FMN binding
D3790_RS06645	COG4657	Part of a membrane complex involved in electron transport
D3790_RS06655	COG0673	inositol 2-dehydrogenase activity
D3790_RS06660	COG0385	Bile acid
D3790_RS06665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D3790_RS06670	COG5339	Protein conserved in bacteria
D3790_RS06675	COG1482	cell wall glycoprotein biosynthetic process
D3790_RS06680	COG0114	fumarate hydratase activity
D3790_RS06700	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D3790_RS06715	COG4221	oxidoreductase activity
D3790_RS06725	COG1902	pentaerythritol trinitrate reductase activity
D3790_RS06735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3790_RS06765	COG1309	transcriptional regulator
D3790_RS06775	COG1069	ribulokinase activity
D3790_RS06800	COG3335	DDE superfamily endonuclease
D3790_RS06845	COG1671	Belongs to the UPF0178 family
D3790_RS06850	COG1396	sequence-specific DNA binding
D3790_RS06855	COG0235	Class ii aldolase
D3790_RS06870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D3790_RS06890	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS06940	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
D3790_RS06940	COG1073	alpha beta
D3790_RS06940	COG3064	Membrane
D3790_RS06970	COG1846	Transcriptional regulator
D3790_RS07020	COG2175	clavaminate synthase activity
D3790_RS07040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3790_RS07045	COG0589	response to stress
D3790_RS07070	COG4974	Belongs to the 'phage' integrase family
D3790_RS07105	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D3790_RS07110	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D3790_RS07130	COG0531	amino acid
D3790_RS07160	COG1643	Atp-dependent helicase
D3790_RS07170	COG3784	Protein of unknown function (DUF1318)
D3790_RS07180	COG2911	Protein conserved in bacteria
D3790_RS07185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D3790_RS07195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D3790_RS07210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D3790_RS07215	COG0494	nUDIX hydrolase
D3790_RS07220	COG2983	Belongs to the UPF0260 family
D3790_RS07225	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3790_RS07230	COG2951	lytic endotransglycosylase activity
D3790_RS07235	COG3100	YcgL domain-containing protein
D3790_RS07240	COG0850	regulation of cytokinetic process
D3790_RS07245	COG2894	cell division
D3790_RS07250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D3790_RS07270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D3790_RS07275	COG0318	PFAM AMP-dependent synthetase and ligase
D3790_RS07280	COG3065	identical protein binding
D3790_RS07290	COG1199	ATP-dependent helicase activity
D3790_RS07310	COG0251	oxidation-reduction process
D3790_RS07315	COG2076	Multidrug Resistance protein
D3790_RS07320	COG2076	Multidrug Resistance protein
D3790_RS07325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D3790_RS07330	COG1737	Transcriptional regulator
D3790_RS07335	COG0469	pyruvate kinase activity
D3790_RS07355	COG1560	Kdo2-lipid A biosynthetic process
D3790_RS07360	COG0739	heme binding
D3790_RS07365	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D3790_RS07370	COG1121	(ABC) transporter
D3790_RS07375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3790_RS07410	COG3321	synthase
D3790_RS07410	COG0604	alcohol dehydrogenase
D3790_RS07420	COG0436	Aminotransferase
D3790_RS07425	COG1509	lysine 2,3-aminomutase activity
D3790_RS07430	COG2255	four-way junction helicase activity
D3790_RS07435	COG0632	four-way junction helicase activity
D3790_RS07440	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D3790_RS07445	COG0217	transcriptional regulatory protein
D3790_RS07450	COG0494	nUDIX hydrolase
D3790_RS07455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D3790_RS07460	COG3788	relative of glutathione S-transferase, MAPEG superfamily
D3790_RS07465	COG2226	methyltransferase
D3790_RS07470	COG0500	methyltransferase
D3790_RS07475	COG3142	Participates in the control of copper homeostasis
D3790_RS07480	COG3102	Protein conserved in bacteria
D3790_RS07485	COG0018	arginyl-trna synthetase
D3790_RS07490	COG0728	peptidoglycan biosynthetic process
D3790_RS07495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D3790_RS07500	COG0477	Major facilitator Superfamily
D3790_RS07510	COG3381	protein complex oligomerization
D3790_RS07515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3790_RS07525	COG0604	alcohol dehydrogenase
D3790_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS07525	COG3321	synthase
D3790_RS07540	COG2378	regulation of single-species biofilm formation
D3790_RS07550	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3790_RS07560	COG0659	secondary active sulfate transmembrane transporter activity
D3790_RS07565	COG3604	Transcriptional regulator
D3790_RS07590	COG2144	transferase activity, transferring acyl groups
D3790_RS07600	COG2072	flavoprotein involved in K transport
D3790_RS07605	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D3790_RS07615	COG2890	protein-(glutamine-N5) methyltransferase activity
D3790_RS07620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D3790_RS07625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D3790_RS07630	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D3790_RS07635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D3790_RS07640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D3790_RS07655	COG0193	aminoacyl-tRNA hydrolase activity
D3790_RS07660	COG0012	GTP binding
D3790_RS07665	COG0402	S-adenosylhomocysteine deaminase activity
D3790_RS07715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D3790_RS07725	COG1271	oxidase subunit
D3790_RS07730	COG1294	oxidase, subunit
D3790_RS07740	COG1702	phosphate starvation-inducible protein PhoH
D3790_RS07745	COG2356	endonuclease I
D3790_RS07760	COG0589	response to stress
D3790_RS07765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3790_RS07770	COG2313	pseudouridylate synthase activity
D3790_RS07775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3790_RS07785	COG0531	amino acid
D3790_RS07790	COG1982	Orn Lys Arg decarboxylase major
D3790_RS07890	COG0076	glutamate decarboxylase activity
D3790_RS07905	COG0501	Belongs to the peptidase M48B family
D3790_RS07940	COG5464	transposase or invertase
D3790_RS07960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3790_RS07975	COG4372	Transposase
D3790_RS07980	COG3436	PFAM IS66 Orf2 family protein
D3790_RS08000	COG1278	Cold shock
D3790_RS08040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D3790_RS08095	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D3790_RS08100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D3790_RS08105	COG0259	pyridoxamine-phosphate oxidase activity
D3790_RS08110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D3790_RS08115	COG3133	Outer membrane lipoprotein
D3790_RS08120	COG1846	Transcriptional regulator
D3790_RS08125	COG3313	Fe-S protein
D3790_RS08130	COG0346	lactoylglutathione lyase activity
D3790_RS08135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3790_RS08140	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D3790_RS08150	COG1609	Transcriptional regulator
D3790_RS08155	COG0583	DNA-binding transcription factor activity
D3790_RS08160	COG2814	Major facilitator Superfamily
D3790_RS08165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D3790_RS08170	COG0307	riboflavin synthase, alpha
D3790_RS08175	COG0534	Mate efflux family protein
D3790_RS08200	COG4238	major outer membrane lipoprotein
D3790_RS08205	COG1388	LysM domain
D3790_RS08205	COG1376	ErfK ybiS ycfS ynhG family protein
D3790_RS08210	COG2050	protein possibly involved in aromatic compounds catabolism
D3790_RS08215	COG0247	lactate metabolic process
D3790_RS08215	COG0277	FAD linked oxidase domain protein
D3790_RS08220	COG0628	permease
D3790_RS08225	COG0574	Belongs to the PEP-utilizing enzyme family
D3790_RS08225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D3790_RS08230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D3790_RS08250	COG3720	iron ion transport
D3790_RS08255	COG4558	Periplasmic binding protein
D3790_RS08260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3790_RS08265	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D3790_RS08275	COG2207	Transcriptional regulator
D3790_RS08280	COG0095	Lipoate-protein ligase
D3790_RS08290	COG1598	PFAM Uncharacterised protein family UPF0150
D3790_RS08300	COG0791	NLP P60 protein
D3790_RS08305	COG2076	Multidrug Resistance protein
D3790_RS08310	COG2076	Multidrug Resistance protein
D3790_RS08315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D3790_RS08320	COG0726	polysaccharide deacetylase
D3790_RS08325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3790_RS08325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3790_RS08330	COG0463	Glycosyl transferase, family 2
D3790_RS08335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3790_RS08340	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
D3790_RS08345	COG4139	cobalamin transport
D3790_RS08350	COG0776	regulation of translation
D3790_RS08355	COG0072	phenylalanine-tRNA ligase activity
D3790_RS08355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3790_RS08370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D3790_RS08375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D3790_RS08380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D3790_RS08390	COG0803	Belongs to the bacterial solute-binding protein 9 family
D3790_RS08395	COG1121	(ABC) transporter
D3790_RS08400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3790_RS08405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D3790_RS08410	COG3001	Fructosamine kinase
D3790_RS08420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3790_RS08425	COG1988	membrane-bound metal-dependent
D3790_RS08455	COG1823	symporter activity
D3790_RS08460	COG0501	Belongs to the peptidase M48B family
D3790_RS08470	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
D3790_RS08475	COG1956	GAF domain-containing protein
D3790_RS08485	COG1276	copper resistance
D3790_RS08490	COG2372	response to copper ion
D3790_RS08495	COG1528	Iron-storage protein
D3790_RS08515	COG3140	Belongs to the UPF0181 family
D3790_RS08525	COG0494	nUDIX hydrolase
D3790_RS08530	COG1760	l-serine dehydratase
D3790_RS08535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3790_RS08535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3790_RS08540	COG3715	PTS system
D3790_RS08545	COG3716	PTS system mannose fructose sorbose family IID component
D3790_RS08550	COG4811	Protein of unknown function (DUF986)
D3790_RS08555	COG1971	Probably functions as a manganese efflux pump
D3790_RS08560	COG2226	methyltransferase
D3790_RS08565	COG2271	Major facilitator Superfamily
D3790_RS08570	COG3851	Histidine kinase
D3790_RS08580	COG3077	Addiction module antitoxin, RelB DinJ family
D3790_RS08590	COG2197	response regulator
D3790_RS08605	COG2197	response regulator
D3790_RS08625	COG0519	Catalyzes the synthesis of GMP from XMP
D3790_RS08625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D3790_RS08630	COG0517	IMP dehydrogenase activity
D3790_RS08630	COG0516	GMP reductase activity
D3790_RS08635	COG1570	exodeoxyribonuclease VII activity
D3790_RS08685	COG3423	Transcriptional regulator
D3790_RS08690	COG3335	DDE superfamily endonuclease
D3790_RS08710	COG2920	part of a sulfur-relay system
D3790_RS08715	COG1254	Belongs to the acylphosphatase family
D3790_RS08725	COG2801	Transposase and inactivated derivatives
D3790_RS08735	COG1832	CoA-binding protein
D3790_RS08740	COG1803	Methylglyoxal synthase
D3790_RS08745	COG0210	DNA helicase
D3790_RS08755	COG5433	transposase activity
D3790_RS08790	COG2801	Transposase and inactivated derivatives
D3790_RS08800	COG3064	Membrane
D3790_RS08800	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
D3790_RS08800	COG3210	domain, Protein
D3790_RS08815	COG3293	Transposase
D3790_RS08830	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D3790_RS08835	COG0745	RESPONSE REGULATOR receiver
D3790_RS08840	COG2201	protein-glutamate methylesterase activity
D3790_RS08850	COG0840	transmembrane signaling receptor activity
D3790_RS08855	COG0840	transmembrane signaling receptor activity
D3790_RS08860	COG0835	chemotaxis
D3790_RS08865	COG0643	Histidine kinase
D3790_RS08865	COG2198	Histidine kinase
D3790_RS08875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D3790_RS08900	COG0418	dihydroorotase activity
D3790_RS08920	COG1620	l-lactate permease
D3790_RS08925	COG1304	FMN binding
D3790_RS08945	COG1560	Kdo2-lipid A biosynthetic process
D3790_RS08950	COG1054	Belongs to the UPF0176 family
D3790_RS08985	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3790_RS09005	COG4384	Bacteriophage Mu Gp45 protein
D3790_RS09015	COG4228	DNA circulation
D3790_RS09025	COG4397	Mu-like prophage major head subunit gpT
D3790_RS09030	COG4388	Caudovirus prohead serine protease
D3790_RS09035	COG5005	Phage virion morphogenesis
D3790_RS09040	COG2369	cell adhesion
D3790_RS09045	COG4383	Mu-like prophage protein gp29
D3790_RS09050	COG4373	Mu-like prophage FluMu protein gp28
D3790_RS09060	COG0640	Transcriptional regulator
D3790_RS09095	COG5566	PFAM Mor transcription activator
D3790_RS09145	COG2842	Transposition protein
D3790_RS09155	COG3423	Transcriptional regulator
D3790_RS09215	COG3335	DDE superfamily endonuclease
D3790_RS09230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3790_RS09235	COG0506	proline dehydrogenase activity
D3790_RS09235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D3790_RS09235	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D3790_RS09245	COG1191	sigma factor activity
D3790_RS09280	COG1677	Flagellar hook-basal body complex protein FliE
D3790_RS09285	COG1766	The M ring may be actively involved in energy transduction
D3790_RS09300	COG1157	protein secretion by the type III secretion system
D3790_RS09315	COG1580	Controls the rotational direction of flagella during chemotaxis
D3790_RS09350	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D3790_RS09390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3790_RS09395	COG4221	oxidoreductase activity
D3790_RS09395	COG3321	synthase
D3790_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS09395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D3790_RS09415	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3790_RS09440	COG1104	cysteine desulfurase activity
D3790_RS09450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D3790_RS09460	COG1705	Flagellar rod assembly protein muramidase FlgJ
D3790_RS09460	COG3951	Flagellar rod assembly protein muramidase FlgJ
D3790_RS09465	COG1706	bacterial-type flagellum-dependent cell motility
D3790_RS09470	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D3790_RS09495	COG1558	bacterial-type flagellum-dependent cell motility
D3790_RS09500	COG1815	bacterial-type flagellum-dependent cell motility
D3790_RS09530	COG3121	Chaperone
D3790_RS09540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3790_RS09545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D3790_RS09620	COG2831	hemolysin activation secretion protein
D3790_RS09665	COG3335	DDE superfamily endonuclease
D3790_RS09685	COG3070	regulator of competence-specific genes
D3790_RS09690	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
D3790_RS09700	COG2885	chlorophyll binding
D3790_RS09700	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D3790_RS09705	COG3120	sequence-specific DNA binding
D3790_RS09710	COG1067	ATP-dependent peptidase activity
D3790_RS09715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3790_RS09720	COG3130	regulation of translation
D3790_RS09725	COG3009	Protein conserved in bacteria
D3790_RS09730	COG3008	intermembrane lipid transfer
D3790_RS09730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D3790_RS09735	COG2995	paraquat-inducible protein a
D3790_RS09740	COG0488	(ABC) transporter
D3790_RS09745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D3790_RS09745	COG0116	Belongs to the methyltransferase superfamily
D3790_RS09750	COG3217	Mosc domain protein beta barrel domain protein
D3790_RS09750	COG0633	Ferredoxin
D3790_RS09760	COG0167	dihydroorotate dehydrogenase activity
D3790_RS09765	COG0308	aminopeptidase N
D3790_RS09770	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D3790_RS09775	COG0017	Asparaginyl-tRNA synthetase
D3790_RS09780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D3790_RS09785	COG1448	Aminotransferase
D3790_RS09790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D3790_RS09795	COG3108	Peptidase M15
D3790_RS09800	COG2989	Protein conserved in bacteria
D3790_RS09810	COG3700	Belongs to the class B bacterial acid phosphatase family
D3790_RS09815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D3790_RS09820	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
D3790_RS09825	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
D3790_RS09830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D3790_RS09835	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D3790_RS09840	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D3790_RS09845	COG2835	tetraacyldisaccharide 4'-kinase activity
D3790_RS09850	COG1663	tetraacyldisaccharide 4'-kinase activity
D3790_RS09855	COG1132	(ABC) transporter
D3790_RS09860	COG2333	competence protein COMEC
D3790_RS09860	COG0658	competence protein
D3790_RS09870	COG0539	negative regulation of cytoplasmic translation
D3790_RS09875	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D3790_RS09880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D3790_RS09885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D3790_RS09895	COG0252	asparaginase activity
D3790_RS09900	COG1944	ATP diphosphatase activity
D3790_RS09905	COG2116	formate transmembrane transporter activity
D3790_RS09910	COG1882	Formate acetyltransferase
D3790_RS09915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D3790_RS09930	COG3293	Transposase
D3790_RS09935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D3790_RS09940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D3790_RS09945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D3790_RS09950	COG3107	peptidoglycan biosynthetic process
D3790_RS09950	COG1674	ftsk spoiiie
D3790_RS09955	COG1522	sequence-specific DNA binding
D3790_RS09960	COG0492	ferredoxin-NADP+ reductase activity
D3790_RS09970	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D3790_RS09975	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D3790_RS09985	COG0542	response to heat
D3790_RS09990	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D3790_RS09995	COG1278	Cold shock
D3790_RS10000	COG3593	DNA synthesis involved in DNA repair
D3790_RS10005	COG2431	L-lysine efflux transmembrane transporter activity
D3790_RS10010	COG1126	abc transporter atp-binding protein
D3790_RS10015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3790_RS10020	COG4215	(ABC) transporter
D3790_RS10025	COG4160	amino acid transport
D3790_RS10030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3790_RS10050	COG0671	phosphoesterase, PA-phosphatase related
D3790_RS10055	COG0814	amino acid
D3790_RS10060	COG1686	Belongs to the peptidase S11 family
D3790_RS10065	COG0625	glutathione transferase activity
D3790_RS10070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3790_RS10080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D3790_RS10085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3790_RS10085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3790_RS10090	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3790_RS10090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D3790_RS10095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D3790_RS10095	COG0131	Imidazoleglycerol-phosphate dehydratase
D3790_RS10100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D3790_RS10105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D3790_RS10110	COG0107	imidazoleglycerol-phosphate synthase activity
D3790_RS10115	COG0140	phosphoribosyl-ATP diphosphatase activity
D3790_RS10115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D3790_RS10120	COG2226	methyltransferase
D3790_RS10135	COG1454	alcohol dehydrogenase
D3790_RS10140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D3790_RS10145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D3790_RS10150	COG1253	flavin adenine dinucleotide binding
D3790_RS10155	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3790_RS10160	COG2982	Protein involved in outer membrane biogenesis
D3790_RS10165	COG0717	Belongs to the dCTP deaminase family
D3790_RS10170	COG0572	uridine kinase
D3790_RS10180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3790_RS10180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D3790_RS10185	COG1380	Effector of murein hydrolase LrgA
D3790_RS10190	COG1346	cytolysis
D3790_RS10195	COG0295	cytidine deaminase activity
D3790_RS10200	COG0281	malic enzyme
D3790_RS10205	COG2949	membrane
D3790_RS10210	COG2311	Membrane
D3790_RS10215	COG0302	gtp cyclohydrolase
D3790_RS10220	COG0477	Major facilitator Superfamily
D3790_RS10230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3790_RS10235	COG0488	(ABC) transporter
D3790_RS10240	COG0454	-acetyltransferase
D3790_RS10250	COG5006	permease, DMT superfamily
D3790_RS10260	COG2824	Alkylphosphonate utilization operon protein PhnA
D3790_RS10275	COG2897	thiosulfate sulfurtransferase activity
D3790_RS10285	COG5433	transposase activity
D3790_RS10315	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3790_RS10345	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3790_RS10425	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3790_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS10435	COG0318	PFAM AMP-dependent synthetase and ligase
D3790_RS10450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D3790_RS10470	COG1492	cobalamin metabolic process
D3790_RS10545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D3790_RS10555	COG1648	precorrin-2 dehydrogenase activity
D3790_RS10555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3790_RS10560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3790_RS10585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3790_RS10600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D3790_RS10610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D3790_RS10615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3790_RS10620	COG4974	Belongs to the 'phage' integrase family
D3790_RS10625	COG0716	FMN binding
D3790_RS10635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D3790_RS10640	COG0354	folic acid binding
D3790_RS10655	COG1216	Glycosyl transferase, family 2
D3790_RS10655	COG1442	glycosyl transferase family 8
D3790_RS10670	COG0463	Glycosyl transferase, family 2
D3790_RS10690	COG0577	efflux transmembrane transporter activity
D3790_RS10690	COG1136	(ABC) transporter
D3790_RS10695	COG1136	(ABC) transporter
D3790_RS10695	COG0577	efflux transmembrane transporter activity
D3790_RS10710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3790_RS10710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D3790_RS10715	COG0509	glycine decarboxylation via glycine cleavage system
D3790_RS10720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D3790_RS10725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3790_RS10730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D3790_RS10735	COG0006	proline dipeptidase activity
D3790_RS10740	COG3079	Belongs to the UPF0149 family
D3790_RS10755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D3790_RS10760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D3790_RS10770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D3790_RS10775	COG0583	DNA-binding transcription factor activity
D3790_RS10785	COG1279	arginine transmembrane transporter activity
D3790_RS10790	COG0668	transmembrane transport
D3790_RS10795	COG3112	Uncharacterised protein family (UPF0231)
D3790_RS10835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D3790_RS10840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3790_RS10845	COG0508	dehydrogenase complex catalyzes the overall conversion of
D3790_RS10850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D3790_RS10855	COG2186	Transcriptional regulator
D3790_RS10860	COG3725	Membrane protein required for beta-lactamase induction
D3790_RS10865	COG3023	N-Acetylmuramoyl-L-alanine amidase
D3790_RS10870	COG4969	Belongs to the N-Me-Phe pilin family
D3790_RS10875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D3790_RS10880	COG1459	type II secretion system
D3790_RS10885	COG0237	dephospho-CoA kinase activity
D3790_RS10890	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
D3790_RS10895	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D3790_RS10900	COG0494	nUDIX hydrolase
D3790_RS10905	COG0488	(ABC) transporter
D3790_RS10910	COG0653	protein targeting
D3790_RS10925	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D3790_RS10935	COG0849	cell division
D3790_RS10940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D3790_RS10945	COG1181	Belongs to the D-alanine--D-alanine ligase family
D3790_RS10950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3790_RS10955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D3790_RS10960	COG0772	Belongs to the SEDS family
D3790_RS10965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D3790_RS10970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3790_RS10975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D3790_RS10980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D3790_RS10985	COG0768	penicillin binding
D3790_RS10990	COG3116	cell division
D3790_RS10995	COG0275	rRNA processing
D3790_RS11000	COG2001	Belongs to the MraZ family
D3790_RS11015	COG0028	Belongs to the TPP enzyme family
D3790_RS11020	COG1022	Amp-dependent synthetase and ligase
D3790_RS11040	COG0473	3-isopropylmalate dehydrogenase activity
D3790_RS11045	COG3066	DNA modification
D3790_RS11055	COG0242	peptide deformylase activity
D3790_RS11065	COG0626	cystathionine gamma-synthase activity
D3790_RS11095	COG3335	DDE superfamily endonuclease
D3790_RS11105	COG2977	Belongs to the P-Pant transferase superfamily
D3790_RS11110	COG0010	Belongs to the arginase family
D3790_RS11115	COG5301	cellulose 1,4-beta-cellobiosidase activity
D3790_RS11120	COG1166	arginine decarboxylase activity
D3790_RS11125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D3790_RS11170	COG3328	transposase activity
D3790_RS11215	COG1509	lysine 2,3-aminomutase activity
D3790_RS11220	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D3790_RS11225	COG0142	geranyltranstransferase activity
D3790_RS11235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3790_RS11235	COG0301	tRNA thio-modification
D3790_RS11240	COG0693	protein deglycase activity
D3790_RS11245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D3790_RS11250	COG1666	GTP binding
D3790_RS11255	COG2814	Major facilitator Superfamily
D3790_RS11260	COG0109	protoheme IX farnesyltransferase activity
D3790_RS11265	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D3790_RS11270	COG1845	cytochrome c oxidase, subunit III
D3790_RS11275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D3790_RS11280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D3790_RS11290	COG2223	nitrite transmembrane transporter activity
D3790_RS11295	COG3056	Lipoprotein
D3790_RS11300	COG0271	Belongs to the BolA IbaG family
D3790_RS11305	COG0544	peptidyl-prolyl cis-trans isomerase activity
D3790_RS11310	COG0740	serine-type endopeptidase activity
D3790_RS11315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D3790_RS11325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D3790_RS11335	COG0776	regulation of translation
D3790_RS11340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3790_RS11345	COG1555	photosystem II stabilization
D3790_RS11350	COG0824	Thioesterase
D3790_RS11355	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D3790_RS11365	COG1522	sequence-specific DNA binding
D3790_RS11370	COG1132	(ABC) transporter
D3790_RS11375	COG1132	(ABC) transporter
D3790_RS11380	COG0347	Belongs to the P(II) protein family
D3790_RS11385	COG0004	ammonium transporteR
D3790_RS11390	COG1946	Acyl-CoA thioesterase
D3790_RS11420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D3790_RS11425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3790_RS11430	COG1309	transcriptional regulator
D3790_RS11435	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D3790_RS11440	COG3264	Mechanosensitive ion channel
D3790_RS11440	COG1196	nuclear chromosome segregation
D3790_RS11455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D3790_RS11470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D3790_RS11475	COG0326	Molecular chaperone. Has ATPase activity
D3790_RS11480	COG0563	adenylate kinase activity
D3790_RS11485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D3790_RS11490	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
D3790_RS11495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3790_RS11500	COG4651	solute:proton antiporter activity
D3790_RS11500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D3790_RS11505	COG2223	nitrite transmembrane transporter activity
D3790_RS11510	COG0737	Belongs to the 5'-nucleotidase family
D3790_RS11525	COG3735	TraB family
D3790_RS11530	COG2217	Heavy metal translocating P-type atpase
D3790_RS11540	COG1585	Membrane protein implicated in regulation of membrane protease activity
D3790_RS11545	COG0330	HflC and HflK could
D3790_RS11550	COG3118	belongs to the thioredoxin family
D3790_RS11555	COG0300	oxidoreductase activity
D3790_RS11560	COG2755	lipolytic protein G-D-S-L family
D3790_RS11565	COG4181	ATPase activity
D3790_RS11570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D3790_RS11585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D3790_RS11590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D3790_RS11595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3790_RS11600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3790_RS11605	COG0215	cysteine-tRNA ligase activity
D3790_RS11645	COG0288	reversible hydration of carbon dioxide
D3790_RS11650	COG1131	(ABC) transporter
D3790_RS11655	COG0842	Transport permease protein
D3790_RS11665	COG0697	spore germination
D3790_RS11675	COG0656	L-ascorbic acid biosynthetic process
D3790_RS11680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D3790_RS11685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D3790_RS11690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D3790_RS11700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D3790_RS11710	COG1489	DNA binding
D3790_RS11715	COG1643	Atp-dependent helicase
D3790_RS11720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3790_RS11725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D3790_RS11730	COG0316	Belongs to the HesB IscA family
D3790_RS11745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D3790_RS11750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D3790_RS11760	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3790_RS11765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3790_RS11770	COG3956	TIGRFAM MazG family protein
D3790_RS11780	COG0504	CTP synthase activity
D3790_RS11785	COG0148	phosphopyruvate hydratase activity
D3790_RS11790	COG0471	metal ion transport
D3790_RS11805	COG1301	dicarboxylic acid transport
D3790_RS11820	COG5433	transposase activity
D3790_RS11825	COG5464	transposase or invertase
D3790_RS11870	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D3790_RS11875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D3790_RS11880	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D3790_RS11885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3790_RS11890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D3790_RS11895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3790_RS11895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D3790_RS11900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D3790_RS11905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D3790_RS11915	COG1862	Preprotein translocase
D3790_RS11925	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D3790_RS11930	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
D3790_RS11935	COG0450	alkyl hydroperoxide reductase
D3790_RS11960	COG5002	protein histidine kinase activity
D3790_RS11965	COG0745	RESPONSE REGULATOR receiver
D3790_RS11970	COG0420	3'-5' exonuclease activity
D3790_RS11975	COG0419	ATPase involved in DNA repair
D3790_RS11980	COG0733	neurotransmitter:sodium symporter activity
D3790_RS12005	COG3719	Belongs to the RNase T2 family
D3790_RS12030	COG0596	Alpha beta hydrolase
D3790_RS12090	COG3561	AntA/AntB antirepressor
D3790_RS12105	COG0582	viral genome integration into host DNA
D3790_RS12125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D3790_RS12130	COG2368	4-hydroxyphenylacetate
D3790_RS12155	COG3971	2-oxopent-4-enoate hydratase activity
D3790_RS12170	COG3384	dioxygenase
D3790_RS12175	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS12185	COG0179	Fumarylacetoacetate (FAA) hydrolase
D3790_RS12190	COG1846	Transcriptional regulator
D3790_RS12200	COG3423	Transcriptional regulator
D3790_RS12240	COG3335	DDE superfamily endonuclease
D3790_RS12325	COG0312	modulator of DNA gyrase
D3790_RS12330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D3790_RS12335	COG3164	Protein of unknown function
D3790_RS12340	COG1530	ribonuclease E activity
D3790_RS12345	COG0424	maF-like protein
D3790_RS12350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D3790_RS12355	COG1792	Involved in formation and maintenance of cell shape
D3790_RS12360	COG1077	Cell shape determining protein MreB Mrl
D3790_RS12365	COG0604	alcohol dehydrogenase
D3790_RS12370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D3790_RS12375	COG0511	ligase activity, forming carbon-carbon bonds
D3790_RS12380	COG0439	Biotin carboxylase
D3790_RS12385	COG3924	membrane
D3790_RS12390	COG4145	pantothenate transmembrane transporter activity
D3790_RS12395	COG2264	protein methyltransferase activity
D3790_RS12400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3790_RS12405	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D3790_RS12410	COG3423	Transcriptional regulator
D3790_RS12425	COG3293	Transposase
D3790_RS12455	COG3335	DDE superfamily endonuclease
D3790_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS12475	COG0697	spore germination
D3790_RS12500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D3790_RS12535	COG0484	heat shock protein binding
D3790_RS12540	COG0443	Heat shock 70 kDa protein
D3790_RS12545	COG1584	GPR1 FUN34 yaaH family protein
D3790_RS12555	COG0521	Mo-molybdopterin cofactor biosynthetic process
D3790_RS12560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D3790_RS12565	COG3022	response to hydroperoxide
D3790_RS12595	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS12600	COG1535	isochorismatase
D3790_RS12600	COG3433	isochorismatase activity
D3790_RS12610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D3790_RS12615	COG2814	Major facilitator Superfamily
D3790_RS12625	COG0083	homoserine kinase activity
D3790_RS12635	COG0745	RESPONSE REGULATOR receiver
D3790_RS12645	COG3045	CreA protein
D3790_RS12650	COG2207	Transcriptional regulator
D3790_RS12650	COG3708	Transcriptional regulator
D3790_RS12655	COG0406	alpha-ribazole phosphatase activity
D3790_RS12660	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D3790_RS12665	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
D3790_RS12670	COG0741	lytic transglycosylase activity
D3790_RS12680	COG0488	(ABC) transporter
D3790_RS12710	COG0410	ABC transporter
D3790_RS12720	COG4177	L-phenylalanine transmembrane transporter activity
D3790_RS12725	COG0559	Belongs to the binding-protein-dependent transport system permease family
D3790_RS12740	COG1929	Belongs to the glycerate kinase type-1 family
D3790_RS12750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D3790_RS12755	COG2177	Part of the ABC transporter FtsEX involved in
D3790_RS12760	COG2884	Cell division ATP-binding protein ftsE
D3790_RS12765	COG0552	protein localization to endoplasmic reticulum
D3790_RS12770	COG0742	ribosomal rna small subunit methyltransferase
D3790_RS12775	COG3776	membrane
D3790_RS12780	COG3714	YhhN family
D3790_RS12790	COG0425	Belongs to the sulfur carrier protein TusA family
D3790_RS12795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D3790_RS12825	COG2271	Major facilitator Superfamily
D3790_RS12830	COG0584	glycerophosphoryl diester phosphodiesterase
D3790_RS12835	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D3790_RS12845	COG1053	succinate dehydrogenase
D3790_RS12850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D3790_RS12855	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
D3790_RS12860	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
D3790_RS12865	COG4771	TonB-dependent receptor
D3790_RS12870	COG4770	biotin carboxylase activity
D3790_RS12880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D3790_RS12920	COG0138	bifunctional purine biosynthesis protein purh
D3790_RS12925	COG0151	Belongs to the GarS family
D3790_RS12945	COG1515	deoxyribonuclease V activity
D3790_RS12950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D3790_RS12955	COG0339	signal peptide processing
D3790_RS12960	COG2816	NAD+ diphosphatase activity
D3790_RS12985	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D3790_RS12990	COG0352	thiamine-phosphate diphosphorylase activity
D3790_RS12995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D3790_RS13000	COG2104	thiamine diphosphate biosynthetic process
D3790_RS13005	COG2022	thiamine diphosphate biosynthetic process
D3790_RS13025	COG3436	PFAM IS66 Orf2 family protein
D3790_RS13030	COG4372	Transposase
D3790_RS13035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3790_RS13035	COG0543	2 iron, 2 sulfur cluster binding
D3790_RS13045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3790_RS13050	COG0765	amino acid transport
D3790_RS13055	COG1126	abc transporter atp-binding protein
D3790_RS13060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3790_RS13080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3790_RS13095	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS13100	COG4638	Rieske (2fe-2S)
D3790_RS13105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D3790_RS13115	COG0583	DNA-binding transcription factor activity
D3790_RS13140	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
D3790_RS13145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D3790_RS13160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D3790_RS13165	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D3790_RS13170	COG1280	lysine exporter protein (LysE YggA)
D3790_RS13175	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
D3790_RS13185	COG0864	Transcriptional regulator
D3790_RS13190	COG1690	Belongs to the RtcB family
D3790_RS13255	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
D3790_RS13275	COG0602	queuosine metabolic process
D3790_RS13280	COG3787	Belongs to the UPF0306 family
D3790_RS13295	COG3153	acetyltransferase
D3790_RS13300	COG3154	lipid carrier protein
D3790_RS13305	COG1470	cell adhesion involved in biofilm formation
D3790_RS13305	COG1388	LysM domain
D3790_RS13310	COG3275	phosphorelay sensor kinase activity
D3790_RS13320	COG0513	Belongs to the DEAD box helicase family
D3790_RS13335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D3790_RS13340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D3790_RS13345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D3790_RS13350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D3790_RS13355	COG0195	Participates in both transcription termination and antitermination
D3790_RS13360	COG0779	Required for maturation of 30S ribosomal subunits
D3790_RS13375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D3790_RS13380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D3790_RS13385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D3790_RS13395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D3790_RS13400	COG1534	Rna-binding protein
D3790_RS13410	COG2027	D-alanyl-D-alanine carboxypeptidase
D3790_RS13415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D3790_RS13420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D3790_RS13425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D3790_RS13430	COG0142	geranyltranstransferase activity
D3790_RS13445	COG3423	Transcriptional regulator
D3790_RS13450	COG0039	L-malate dehydrogenase activity
D3790_RS13460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D3790_RS13465	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D3790_RS13475	COG2105	PFAM AIG2 family protein
D3790_RS13485	COG0729	surface antigen
D3790_RS13490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D3790_RS13495	COG1253	flavin adenine dinucleotide binding
D3790_RS13505	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D3790_RS13515	COG2337	Toxic component of a toxin-antitoxin (TA) module
D3790_RS13525	COG0545	Peptidyl-prolyl cis-trans isomerase
D3790_RS13550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D3790_RS13555	COG2965	DNA replication, synthesis of RNA primer
D3790_RS13560	COG0360	Binds together with S18 to 16S ribosomal RNA
D3790_RS13565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3790_RS13570	COG0557	exoribonuclease II activity
D3790_RS13575	COG1959	2 iron, 2 sulfur cluster binding
D3790_RS13580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D3790_RS13585	COG0330	HflC and HflK could
D3790_RS13590	COG0330	HflC and HflK could
D3790_RS13595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D3790_RS13600	COG1923	regulation of RNA biosynthetic process
D3790_RS13605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D3790_RS13610	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D3790_RS13615	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3790_RS13620	COG0802	atpase or kinase
D3790_RS13625	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D3790_RS13630	COG2368	4-hydroxyphenylacetate
D3790_RS13635	COG2368	4-hydroxyphenylacetate
D3790_RS13640	COG1960	acyl-CoA dehydrogenase activity
D3790_RS13645	COG3033	Beta-eliminating lyase
D3790_RS13655	COG0477	Major facilitator Superfamily
D3790_RS13660	COG0583	DNA-binding transcription factor activity
D3790_RS13690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D3790_RS13695	COG1162	GTPase activity
D3790_RS13700	COG0688	phosphatidylethanolamine metabolic process
D3790_RS13705	COG3264	Mechanosensitive ion channel
D3790_RS13705	COG1511	domain protein
D3790_RS13720	COG3152	Membrane
D3790_RS13725	COG1609	Transcriptional regulator
D3790_RS13730	COG0477	Major facilitator Superfamily
D3790_RS13735	COG0561	phosphatase activity
D3790_RS13740	COG2267	carboxylic ester hydrolase activity
D3790_RS13745	COG0514	ATP-dependent DNA helicase (RecQ)
D3790_RS13755	COG2050	protein possibly involved in aromatic compounds catabolism
D3790_RS13780	COG0598	Magnesium transport protein CorA
D3790_RS13785	COG0210	DNA helicase
D3790_RS13790	COG1011	Hydrolase
D3790_RS13795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D3790_RS13800	COG3159	Protein conserved in bacteria
D3790_RS13805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D3790_RS13815	COG1965	Belongs to the frataxin family
D3790_RS13825	COG0181	hydroxymethylbilane synthase activity
D3790_RS13835	COG2959	enzyme of heme biosynthesis
D3790_RS13840	COG3071	HemY protein
D3790_RS13870	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D3790_RS13880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D3790_RS13885	COG2244	polysaccharide biosynthetic process
D3790_RS13890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3790_RS13895	COG0456	acetyltransferase
D3790_RS13900	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D3790_RS13905	COG1088	dTDP-glucose 4,6-dehydratase activity
D3790_RS13910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D3790_RS13915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D3790_RS13920	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
D3790_RS13925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D3790_RS13930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D3790_RS13940	COG3118	belongs to the thioredoxin family
D3790_RS13945	COG0513	Belongs to the DEAD box helicase family
D3790_RS13950	COG0248	Ppx GppA phosphatase
D3790_RS13955	COG0210	DNA helicase
D3790_RS13965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D3790_RS13990	COG0129	dihydroxy-acid dehydratase activity
D3790_RS13995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D3790_RS14000	COG3978	acetolactate synthase activity
D3790_RS14020	COG3085	chromosome segregation
D3790_RS14025	COG0583	DNA-binding transcription factor activity
D3790_RS14065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D3790_RS14075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D3790_RS14080	COG0009	L-threonylcarbamoyladenylate synthase
D3790_RS14085	COG0551	DNA topoisomerase type I activity
D3790_RS14090	COG0758	DNA mediated transformation
D3790_RS14095	COG0242	peptide deformylase activity
D3790_RS14100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D3790_RS14105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D3790_RS14105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D3790_RS14110	COG0569	domain protein
D3790_RS14115	COG3036	rescue of stalled ribosome
D3790_RS14120	COG0789	Transcriptional regulator
D3790_RS14125	COG0203	ribosomal protein L17
D3790_RS14130	COG0202	RNA polymerase activity
D3790_RS14135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D3790_RS14145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3790_RS14150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3790_RS14155	COG0201	protein transport
D3790_RS14160	COG0200	Binds to the 23S rRNA
D3790_RS14165	COG1841	ribosomal large subunit assembly
D3790_RS14170	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D3790_RS14175	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D3790_RS14180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D3790_RS14185	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D3790_RS14190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D3790_RS14195	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D3790_RS14200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D3790_RS14205	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D3790_RS14210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D3790_RS14220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D3790_RS14235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D3790_RS14240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D3790_RS14250	COG0088	Forms part of the polypeptide exit tunnel
D3790_RS14255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D3790_RS14260	COG0051	transcription antitermination factor activity, RNA binding
D3790_RS14265	COG5433	transposase activity
D3790_RS14285	COG3344	reverse transcriptase
D3790_RS14310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D3790_RS14345	COG1072	(Pantothenic acid kinase))
D3790_RS14355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D3790_RS14390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D3790_RS14395	COG4206	TonB-dependent receptor
D3790_RS14400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D3790_RS14415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3790_RS14425	COG0165	Argininosuccinate lyase
D3790_RS14430	COG0137	argininosuccinate synthase activity
D3790_RS14440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D3790_RS14445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D3790_RS14450	COG1598	PFAM Uncharacterised protein family UPF0150
D3790_RS14465	COG1724	mRNA binding
D3790_RS14475	COG3077	Addiction module antitoxin, RelB DinJ family
D3790_RS14490	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D3790_RS14495	COG0527	aspartate kinase activity
D3790_RS14495	COG0460	homoserine dehydrogenase
D3790_RS14500	COG0626	cystathionine gamma-synthase activity
D3790_RS14505	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
D3790_RS14515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D3790_RS14520	COG1609	Transcriptional regulator
D3790_RS14525	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D3790_RS14530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D3790_RS14535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D3790_RS14540	COG1575	Belongs to the MenA family. Type 1 subfamily
D3790_RS14545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D3790_RS14550	COG3074	FtsZ-dependent cytokinesis
D3790_RS14565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D3790_RS14570	COG2814	Major facilitator Superfamily
D3790_RS14580	COG3152	Membrane
D3790_RS14590	COG0149	triose-phosphate isomerase activity
D3790_RS14630	COG3645	SOS response
D3790_RS14695	COG1561	YicC-like family, N-terminal region
D3790_RS14700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D3790_RS14705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D3790_RS14710	COG1309	transcriptional regulator
D3790_RS14715	COG0756	dUTP diphosphatase activity
D3790_RS14720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D3790_RS14725	COG2003	Belongs to the UPF0758 family
D3790_RS14740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D3790_RS14745	COG0438	transferase activity, transferring glycosyl groups
D3790_RS14755	COG0438	transferase activity, transferring glycosyl groups
D3790_RS14770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D3790_RS14775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D3790_RS14785	COG1519	Transferase
D3790_RS14790	COG0859	PFAM glycosyl transferase family 9
D3790_RS14800	COG0438	transferase activity, transferring glycosyl groups
D3790_RS14830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3790_RS14835	COG0156	8-amino-7-oxononanoate synthase activity
D3790_RS14840	COG1063	alcohol dehydrogenase
D3790_RS14845	COG2861	carbohydrate metabolic process
D3790_RS14850	COG4942	peptidase
D3790_RS14860	COG3657	addiction module killer protein
D3790_RS14865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3790_RS14870	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D3790_RS14875	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D3790_RS14880	COG1045	serine acetyltransferase
D3790_RS14885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D3790_RS14920	COG3293	Transposase
D3790_RS14940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D3790_RS14945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D3790_RS15055	COG0673	inositol 2-dehydrogenase activity
D3790_RS15065	COG2205	protein histidine kinase activity
D3790_RS15070	COG0745	RESPONSE REGULATOR receiver
D3790_RS15075	COG3678	ATP-independent chaperone mediated protein folding
D3790_RS15085	COG1724	mRNA binding
D3790_RS15090	COG1598	PFAM Uncharacterised protein family UPF0150
D3790_RS15105	COG2944	sequence-specific DNA binding
D3790_RS15120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D3790_RS15125	COG0205	6-phosphofructokinase activity
D3790_RS15130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D3790_RS15135	COG3177	Filamentation induced by cAMP protein fic
D3790_RS15150	COG3609	addiction module antidote protein, CC2985 family
D3790_RS15155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3790_RS15165	COG2188	Transcriptional regulator
D3790_RS15170	COG1368	sulfuric ester hydrolase activity
D3790_RS15175	COG3276	selenocysteine insertion sequence binding
D3790_RS15175	COG3276	selenocysteine insertion sequence binding
D3790_RS15180	COG3058	Necessary for formate dehydrogenase activity
D3790_RS15205	COG2864	formate dehydrogenase
D3790_RS15210	COG0243	molybdopterin cofactor binding
D3790_RS15210	COG3383	formate dehydrogenase (NAD+) activity
D3790_RS15215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D3790_RS15240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
D3790_RS15245	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3790_RS15260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D3790_RS15280	COG4796	Type ii and iii secretion system protein
D3790_RS15290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D3790_RS15295	COG3266	domain, Protein
D3790_RS15305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D3790_RS15310	COG0546	phosphoglycolate phosphatase activity
D3790_RS15315	COG0180	Tryptophanyl-tRNA synthetase
D3790_RS15320	COG2258	MOSC domain
D3790_RS15330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D3790_RS15335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D3790_RS15340	COG3162	membrane
D3790_RS15345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D3790_RS15375	COG0477	Major facilitator Superfamily
D3790_RS15380	COG1609	Transcriptional regulator
D3790_RS15385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D3790_RS15400	COG0714	Associated with various cellular activities
D3790_RS15405	COG2425	protein containing a von Willebrand factor type A (vWA) domain
D3790_RS15410	COG2502	aspartate--ammonia ligase
D3790_RS15415	COG1522	sequence-specific DNA binding
D3790_RS15420	COG0716	FMN binding
D3790_RS15425	COG0445	tRNA wobble uridine modification
D3790_RS15430	COG0357	Ribosomal RNA small subunit methyltransferase G
D3790_RS15435	COG3312	ion transport
D3790_RS15440	COG0356	it plays a direct role in the translocation of protons across the membrane
D3790_RS15450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D3790_RS15455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D3790_RS15460	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D3790_RS15465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D3790_RS15470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D3790_RS15475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D3790_RS15480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D3790_RS15485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D3790_RS15495	COG0732	type I restriction modification DNA specificity domain
D3790_RS15500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D3790_RS15525	COG0254	rRNA binding
D3790_RS15530	COG0254	rRNA binding
D3790_RS15535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D3790_RS15540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D3790_RS15560	COG0187	DNA topoisomerase II activity
D3790_RS15565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3790_RS15570	COG0592	DNA-directed DNA polymerase activity
D3790_RS15580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D3790_RS15585	COG0594	ribonuclease P activity
D3790_RS15590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D3790_RS15595	COG0706	membrane insertase activity
D3790_RS15600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D3790_RS15605	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D3790_RS15630	COG3038	cytochrome b561
D3790_RS15660	COG3327	negative regulation of DNA-templated transcription, initiation
D3790_RS15675	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D3790_RS15680	COG0183	Belongs to the thiolase family
D3790_RS15685	COG2050	protein possibly involved in aromatic compounds catabolism
D3790_RS15690	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3790_RS15695	COG1024	Enoyl-CoA hydratase
D3790_RS15700	COG1024	Enoyl-CoA hydratase
D3790_RS15705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D3790_RS15710	COG2151	metal-sulfur cluster biosynthetic enzyme
D3790_RS15715	COG3396	Phenylacetate-CoA oxygenase
D3790_RS15720	COG3460	Phenylacetate-CoA oxygenase
D3790_RS15725	COG3396	Phenylacetate-CoA oxygenase
D3790_RS15730	COG2030	dehydratase
D3790_RS15730	COG1012	belongs to the aldehyde dehydrogenase family
D3790_RS15735	COG4680	protein conserved in bacteria
D3790_RS15740	COG5499	transcription regulator containing HTH domain
D3790_RS15760	COG0306	phosphate transporter
D3790_RS15765	COG2081	HI0933 family
D3790_RS15800	COG1741	Belongs to the pirin family
D3790_RS15805	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D3790_RS15810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D3790_RS15815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D3790_RS15825	COG0494	nUDIX hydrolase
D3790_RS15835	COG1263	PTS System
D3790_RS15835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3790_RS15840	COG0366	Alpha amylase catalytic
D3790_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
D3790_RS15955	COG1942	4-Oxalocrotonate Tautomerase
D3790_RS15960	COG1295	ribonuclease BN
D3790_RS16080	COG3335	DDE superfamily endonuclease
D3790_RS16150	COG2204	response regulator
D3790_RS16175	COG3078	GTPase activator activity
D3790_RS16220	COG3157	Type VI secretion system effector, Hcp
D3790_RS16225	COG0765	amino acid transport
D3790_RS16230	COG0765	amino acid transport
D3790_RS16235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D3790_RS16240	COG0704	Plays a role in the regulation of phosphate uptake
D3790_RS16245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D3790_RS16250	COG0581	inorganic phosphate transmembrane transporter activity
D3790_RS16255	COG0573	inorganic phosphate transmembrane transporter activity
D3790_RS16260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D3790_RS16275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3790_RS16280	COG2183	response to ionizing radiation
D3790_RS16290	COG1918	ferrous iron import across plasma membrane
D3790_RS16310	COG0339	signal peptide processing
D3790_RS16315	COG0742	ribosomal rna small subunit methyltransferase
D3790_RS16325	COG0589	response to stress
D3790_RS16340	COG0626	cystathionine gamma-synthase activity
D3790_RS16355	COG1735	metal-dependent hydrolase with the TIM-barrel fold
D3790_RS16360	COG3457	Alanine racemase
D3790_RS16370	COG2188	Transcriptional regulator
D3790_RS16375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D3790_RS16385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D3790_RS16390	COG1349	DNA-binding transcription factor activity
D3790_RS16395	COG0705	Rhomboid family
D3790_RS16400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D3790_RS16410	COG0316	Belongs to the HesB IscA family
D3790_RS16410	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D3790_RS16420	COG0596	Alpha beta hydrolase
D3790_RS16440	COG0612	Peptidase, M16
D3790_RS16445	COG0675	Transposase, IS605 OrfB family
D3790_RS16455	COG2199	diguanylate cyclase activity
D3790_RS16455	COG2200	EAL domain
D3790_RS16460	COG4608	Belongs to the ABC transporter superfamily
D3790_RS16465	COG0444	Belongs to the ABC transporter superfamily
D3790_RS16470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D3790_RS16475	COG0601	transmembrane transport
D3790_RS16480	COG0747	negative chemotaxis
D3790_RS16495	COG0751	glycine-tRNA ligase activity
D3790_RS16500	COG0752	glycyl-tRNA synthetase alpha subunit
D3790_RS16505	COG2818	Glycosylase
D3790_RS16520	COG0641	radical SAM
D3790_RS16530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D3790_RS16540	COG5645	(Lipo)protein
D3790_RS16545	COG0823	Involved in the tonB-independent uptake of proteins
D3790_RS16550	COG2860	membrane
D3790_RS16555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D3790_RS16560	COG0194	GDP metabolic process
D3790_RS16570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D3790_RS16575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D3790_RS16580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D3790_RS16585	COG0786	glutamate:sodium symporter activity
D3790_RS16590	COG2233	PERMEase
D3790_RS16595	COG2982	Protein involved in outer membrane biogenesis
D3790_RS16600	COG0456	acetyltransferase
D3790_RS16605	COG1490	D-aminoacyl-tRNA deacylase activity
D3790_RS16665	COG3344	reverse transcriptase
D3790_RS16725	COG0726	polysaccharide deacetylase
D3790_RS16730	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D3790_RS16735	COG0085	RNA polymerase activity
D3790_RS16740	COG0222	ribosome binding
D3790_RS16745	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D3790_RS16750	COG0081	regulation of translation
D3790_RS16755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D3790_RS16760	COG0250	Participates in transcription elongation, termination and antitermination
D3790_RS16770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D3790_RS16775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D3790_RS16780	COG0049	tRNA binding
D3790_RS16785	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D3790_RS16790	COG2168	tRNA wobble position uridine thiolation
D3790_RS16795	COG2923	Belongs to the DsrF TusC family
D3790_RS16800	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D3790_RS16805	COG2964	Protein conserved in bacteria
D3790_RS16810	COG0545	Peptidyl-prolyl cis-trans isomerase
D3790_RS16815	COG2900	Belongs to the SlyX family
D3790_RS16830	COG0483	inositol monophosphate 1-phosphatase activity
D3790_RS16835	COG2813	Specifically methylates the guanine in position
D3790_RS16850	COG2234	aminopeptidase activity
D3790_RS16860	COG1047	Peptidyl-prolyl cis-trans
D3790_RS16865	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D3790_RS16875	COG2249	NAD(P)H dehydrogenase (quinone) activity
D3790_RS16880	COG0488	(ABC) transporter
D3790_RS16890	COG0583	DNA-binding transcription factor activity
D3790_RS16900	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D3790_RS16905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D3790_RS16905	COG1263	PTS System
D3790_RS16910	COG1280	lysine exporter protein (LysE YggA)
D3790_RS16915	COG0429	hydrolase of the alpha beta-hydrolase fold
D3790_RS16920	COG3089	Belongs to the UPF0270 family
D3790_RS16925	COG3954	Phosphoribulokinase
D3790_RS16930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D3790_RS16935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D3790_RS16945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D3790_RS16955	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D3790_RS16960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3790_RS16960	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3790_RS16965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D3790_RS16970	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D3790_RS16980	COG1763	Mo-molybdopterin cofactor biosynthetic process
D3790_RS16985	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D3790_RS16990	COG1830	Aldolase
D3790_RS16995	COG1879	ABC-type sugar transport system periplasmic component
D3790_RS17000	COG1070	Carbohydrate kinase
D3790_RS17025	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D3790_RS17030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D3790_RS17090	COG3335	DDE superfamily endonuclease
D3790_RS17120	COG4580	involved in the transport of maltose and maltodextrins
D3790_RS17125	COG3842	ATPase activity
D3790_RS17130	COG2182	Extracellular solute-binding protein
D3790_RS17135	COG1175	transmembrane transport
D3790_RS17140	COG3833	ABC-type maltose transport systems, permease component
D3790_RS17145	COG1640	4-alpha-glucanotransferase
D3790_RS17150	COG0058	SHG alpha-glucan phosphorylase activity
D3790_RS17155	COG2909	trisaccharide binding
D3790_RS17165	COG1063	alcohol dehydrogenase
D3790_RS17170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D3790_RS17175	COG2223	nitrite transmembrane transporter activity
D3790_RS17190	COG4372	Transposase
D3790_RS17195	COG3436	PFAM IS66 Orf2 family protein
D3790_RS17220	COG0525	valine-tRNA ligase activity
D3790_RS17225	COG2927	DNA polymerase III (CHI subunit)
D3790_RS17230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D3790_RS17235	COG0795	lipopolysaccharide-transporting ATPase activity
D3790_RS17240	COG0795	lipopolysaccharide-transporting ATPase activity
D3790_RS17245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D3790_RS17255	COG0582	viral genome integration into host DNA
D3790_RS17265	COG2801	Transposase and inactivated derivatives
D3790_RS17300	COG0402	S-adenosylhomocysteine deaminase activity
D3790_RS17315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D3790_RS17320	COG3293	Transposase
D3790_RS17335	COG1396	sequence-specific DNA binding
D3790_RS17340	COG3550	peptidyl-serine autophosphorylation
D3790_RS17345	COG1301	dicarboxylic acid transport
D3790_RS17350	COG0583	DNA-binding transcription factor activity
D3790_RS17355	COG1794	racemase activity, acting on amino acids and derivatives
D3790_RS17360	COG3586	endonuclease activity
D3790_RS17400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D3790_RS17405	COG3328	transposase activity
D3790_RS17425	COG3028	Belongs to the UPF0307 family
D3790_RS17430	COG0312	modulator of DNA gyrase
D3790_RS17450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D3790_RS17465	COG3676	manually curated
D3790_RS17480	COG0583	DNA-binding transcription factor activity
D3790_RS17490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D3790_RS17495	COG1660	Displays ATPase and GTPase activities
D3790_RS17505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D3790_RS17510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D3790_RS17515	COG1137	ATPase activity
D3790_RS17520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D3790_RS17525	COG3117	lipopolysaccharide transmembrane transporter activity
D3790_RS17530	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D3790_RS17535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D3790_RS17535	COG0517	IMP dehydrogenase activity
D3790_RS17540	COG0530	calcium, potassium:sodium antiporter activity
D3790_RS17545	COG1127	ABC transporter
D3790_RS17550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D3790_RS17555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D3790_RS17560	COG2854	intermembrane phospholipid transfer
D3790_RS17565	COG3113	response to antibiotic
D3790_RS17570	COG5007	Belongs to the BolA IbaG family
D3790_RS17575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D3790_RS17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3790_RS17585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D3790_RS17595	COG3105	Protein conserved in bacteria
D3790_RS17600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D3790_RS17605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D3790_RS17610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D3790_RS17615	COG0625	glutathione transferase activity
D3790_RS17620	COG2969	positive regulation of protein catabolic process
D3790_RS17630	COG0493	'glutamate synthase
D3790_RS17635	COG0069	glutamate synthase activity
D3790_RS17635	COG0070	glutamate synthase
D3790_RS17635	COG0067	glutamate synthase
D3790_RS17645	COG0784	Response regulator, receiver
D3790_RS17645	COG2198	Histidine kinase
D3790_RS17645	COG5002	protein histidine kinase activity
D3790_RS17650	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D3790_RS17655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D3790_RS17670	COG2823	Periplasmic or secreted lipoprotein
D3790_RS17675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D3790_RS17680	COG0792	nuclease activity
D3790_RS17690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D3790_RS17705	COG1741	Belongs to the pirin family
D3790_RS17710	COG0583	DNA-binding transcription factor activity
D3790_RS17715	COG2259	Doxx family
D3790_RS17725	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
D3790_RS17730	COG4575	ribosome binding
D3790_RS17735	COG0586	Pfam SNARE associated Golgi protein
D3790_RS17740	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D3790_RS17745	COG1902	pentaerythritol trinitrate reductase activity
D3790_RS17745	COG0446	pyridine nucleotide-disulphide oxidoreductase
D3790_RS17755	COG2990	Protein conserved in bacteria
D3790_RS17770	COG0477	Major facilitator Superfamily
D3790_RS17845	COG0582	viral genome integration into host DNA
D3790_RS17875	COG5433	transposase activity
D3790_RS17930	COG1802	Transcriptional regulator
D3790_RS17930	COG4626	Terminase
D3790_RS17940	COG3423	Transcriptional regulator
D3790_RS17960	COG0358	DNA primase activity
D3790_RS17965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D3790_RS17970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D3790_RS17980	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D3790_RS17985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D3790_RS17995	COG4991	sh3 domain protein
D3790_RS18000	COG3025	triphosphatase activity
D3790_RS18005	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D3790_RS18010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D3790_RS18010	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D3790_RS18020	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D3790_RS18025	COG3384	dioxygenase
D3790_RS18030	COG0754	glutathionylspermidine amidase activity
D3790_RS18035	COG5463	Belongs to the UPF0441 family
D3790_RS18040	COG1538	Outer membrane efflux protein
D3790_RS18045	COG0494	nUDIX hydrolase
D3790_RS18050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D3790_RS18055	COG3150	esterase
D3790_RS18065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D3790_RS18070	COG0204	Acyl-transferase
D3790_RS18075	COG2132	Multicopper oxidase
D3790_RS18085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D3790_RS18090	COG2967	ApaG domain
D3790_RS18095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D3790_RS18100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D3790_RS18105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D3790_RS18110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D3790_RS18115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D3790_RS18120	COG0564	pseudouridine synthase activity
D3790_RS18125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D3790_RS18140	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
D3790_RS18145	COG1178	ABC-type Fe3 transport system permease component
D3790_RS18150	COG4143	(ABC) transporter
D3790_RS18155	COG0494	nUDIX hydrolase
D3790_RS18165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D3790_RS18170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D3790_RS18185	COG2175	clavaminate synthase activity
D3790_RS18190	COG2165	general secretion pathway protein
D3790_RS18195	COG4795	General secretion pathway protein
D3790_RS18210	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D3790_RS18220	COG1074	ATP-dependent DNA helicase activity
D3790_RS18225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D3790_RS18235	COG0860	N-Acetylmuramoyl-L-alanine amidase
D3790_RS18255	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D3790_RS18260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D3790_RS18265	COG2166	iron-sulfur cluster assembly
D3790_RS18270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D3790_RS18275	COG0583	DNA-binding transcription factor activity
D3790_RS18280	COG2363	Small membrane protein
D3790_RS18285	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
D3790_RS18315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D3790_RS18325	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D3790_RS18325	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D3790_RS18340	COG3098	single-species biofilm formation
D3790_RS18345	COG0564	pseudouridine synthase activity
D3790_RS18390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D3790_RS18400	COG0052	Belongs to the universal ribosomal protein uS2 family
D3790_RS18405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D3790_RS18410	COG0528	UMP kinase activity
D3790_RS18415	COG0233	cytoplasmic translational termination
D3790_RS18420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D3790_RS18425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D3790_RS18430	COG0575	Belongs to the CDS family
D3790_RS18435	COG0750	zinc metalloprotease
D3790_RS18440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D3790_RS18450	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3790_RS18455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D3790_RS18460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3790_RS18465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D3790_RS18470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D3790_RS18480	COG0825	malonyl-CoA metabolic process
D3790_RS18490	COG0037	tRNA processing
D3790_RS18495	COG4568	rho-dependent transcription termination
D3790_RS18500	COG3015	lipoprotein NlpE involved in copper resistance
D3790_RS18505	COG0442	prolyl-tRNA aminoacylation
D3790_RS18510	COG1720	tRNA m6t6A37 methyltransferase activity
D3790_RS18520	COG1464	Belongs to the NlpA lipoprotein family
D3790_RS18530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D3790_RS18535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D3790_RS18565	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D3790_RS18570	COG3423	Transcriptional regulator
D3790_RS18575	COG1802	Transcriptional regulator
D3790_RS18575	COG4626	Terminase
D3790_RS18665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D3790_RS18670	COG2224	Isocitrate lyase
D3790_RS18675	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
D3790_RS18685	COG0800	Aldolase
D3790_RS18690	COG1414	Transcriptional regulator
D3790_RS18705	COG0527	aspartate kinase activity
D3790_RS18710	COG0166	Belongs to the GPI family
D3790_RS18715	COG3161	chorismate lyase activity
D3790_RS18720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D3790_RS18725	COG2937	Belongs to the GPAT DAPAT family
D3790_RS18730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D3790_RS18740	COG0735	belongs to the Fur family
D3790_RS18760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D3790_RS18775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D3790_RS18795	COG1448	Aminotransferase
D3790_RS18835	COG0837	glucose binding
D3790_RS18840	COG2146	nitrite reductase [NAD(P)H] activity
D3790_RS18845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3790_RS18880	COG2252	PERMEase
D3790_RS18900	COG2366	antibiotic biosynthetic process
D3790_RS18910	COG0025	NhaP-type Na H and K H
D3790_RS18920	COG0583	DNA-binding transcription factor activity
D3790_RS18925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D3790_RS18935	COG2610	gluconate transmembrane transporter activity
D3790_RS18940	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D3790_RS18950	COG0586	Pfam SNARE associated Golgi protein
D3790_RS18955	COG2226	methyltransferase
D3790_RS18960	COG3165	ubiquinone biosynthetic process from chorismate
D3790_RS18965	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D3790_RS18970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3790_RS18975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D3790_RS18980	COG0805	protein transport
D3790_RS18995	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D3790_RS19005	COG0183	Belongs to the thiolase family
D3790_RS19010	COG1250	3-hydroxyacyl-CoA dehydrogenase
D3790_RS19010	COG1024	Enoyl-CoA hydratase
D3790_RS19015	COG0006	proline dipeptidase activity
D3790_RS19020	COG1739	Uncharacterized protein family UPF0029
D3790_RS19030	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
D3790_RS19065	COG3021	interspecies interaction between organisms
D3790_RS19075	COG0602	queuosine metabolic process
D3790_RS19080	COG0720	synthase
D3790_RS19085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D3790_RS19090	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D3790_RS19095	COG0175	sulfate reduction
D3790_RS19100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D3790_RS19100	COG1648	precorrin-2 dehydrogenase activity
D3790_RS19105	COG0175	sulfate reduction
D3790_RS19110	COG2895	sulfate adenylyltransferase (ATP) activity
D3790_RS19115	COG0529	Catalyzes the synthesis of activated sulfate
D3790_RS19120	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D3790_RS19125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D3790_RS19130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D3790_RS19135	COG0585	pseudouridine synthase activity
D3790_RS19140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D3790_RS19145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D3790_RS19150	COG1388	LysM domain
D3790_RS19150	COG4942	peptidase
D3790_RS19165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D3790_RS19180	COG1966	Carbon starvation protein
D3790_RS19185	COG2879	small protein
D3790_RS19190	COG0523	cobalamin synthesis protein
D3790_RS19195	COG0582	viral genome integration into host DNA
D3790_RS19200	COG0814	amino acid
D3790_RS19210	COG3091	SprT-like family
D3790_RS19225	COG0657	acetylesterase activity
D3790_RS19290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D3790_RS19300	COG4667	esterase of the alpha-beta hydrolase superfamily
D3790_RS19305	COG0084	hydrolase, TatD family'
D3790_RS19310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D3790_RS19315	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D3790_RS19320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D3790_RS19325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D3790_RS19330	COG0813	purine-nucleoside phosphorylase activity
D3790_RS19340	COG3188	usher protein
D3790_RS19345	COG3121	Chaperone
D3790_RS19365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D3790_RS19370	COG0505	Belongs to the CarA family
D3790_RS19375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D3790_RS19390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D3790_RS19395	COG1047	Peptidyl-prolyl cis-trans
D3790_RS19400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D3790_RS19405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D3790_RS19410	COG0196	riboflavin kinase activity
D3790_RS19415	COG0268	Binds directly to 16S ribosomal RNA
D3790_RS19420	COG0583	DNA-binding transcription factor activity
D3790_RS19425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D3790_RS19440	COG0737	Belongs to the 5'-nucleotidase family
D3790_RS19445	COG1940	carbohydrate kinase activity
D3790_RS19450	COG2974	May be involved in recombination
D3790_RS19505	COG0848	biopolymer transport protein
D3790_RS19515	COG0626	cystathionine gamma-synthase activity
D3790_RS19525	COG0656	L-ascorbic acid biosynthetic process
D3790_RS19535	COG3726	membrane protein affecting hemolysin expression
D3790_RS19540	COG0560	Phosphoserine phosphatase
D3790_RS19545	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D3790_RS19550	COG3335	DDE superfamily endonuclease
D3790_RS19560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D3790_RS19565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D3790_RS19580	COG4115	mRNA cleavage
D3790_RS19590	COG1120	ATPase activity
D3790_RS19595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3790_RS19600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D3790_RS19605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D3790_RS19610	COG4772	TonB-dependent receptor
D3790_RS19615	COG3712	iron ion homeostasis
D3790_RS19620	COG1595	DNA-templated transcription, initiation
D3790_RS19630	COG2873	o-acetylhomoserine
D3790_RS19680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D3790_RS19685	COG1518	maintenance of DNA repeat elements
D3790_RS19715	COG1203	CRISPR-associated helicase, Cas3
D3790_RS19745	COG2226	methyltransferase