locus-tag	class	description
ET471_RS00030	COG1196	nuclear chromosome segregation
ET471_RS00030	COG0739	heme binding
ET471_RS00030	COG0741	lytic transglycosylase activity
ET471_RS00060	COG2963	transposase activity
ET471_RS00105	COG1136	(ABC) transporter
ET471_RS00105	COG0577	efflux transmembrane transporter activity
ET471_RS00120	COG1569	PIN domain
ET471_RS00125	COG3311	Transcriptional regulator
ET471_RS00185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS00190	COG0066	3-isopropylmalate dehydratase activity
ET471_RS00195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ET471_RS00200	COG1414	Transcriptional regulator
ET471_RS00235	COG0745	RESPONSE REGULATOR receiver
ET471_RS00255	COG1136	(ABC) transporter
ET471_RS00255	COG0577	efflux transmembrane transporter activity
ET471_RS00265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ET471_RS00340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ET471_RS00345	COG3304	Inner membrane component domain
ET471_RS00350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ET471_RS00355	COG0095	Lipoate-protein ligase
ET471_RS00365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ET471_RS00370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ET471_RS00375	COG0473	3-isopropylmalate dehydrogenase activity
ET471_RS00385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ET471_RS00390	COG0440	acetolactate synthase activity
ET471_RS00400	COG2154	pterin-4-alpha-carbinolamine dehydratase
ET471_RS00405	COG0129	dihydroxy-acid dehydratase activity
ET471_RS00410	COG0129	dihydroxy-acid dehydratase activity
ET471_RS00415	COG3104	oligopeptide transport
ET471_RS00425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ET471_RS00430	COG0154	amidase activity
ET471_RS00435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ET471_RS00480	COG1879	ABC-type sugar transport system periplasmic component
ET471_RS00485	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET471_RS00490	COG1129	ABC transporter
ET471_RS00505	COG1012	belongs to the aldehyde dehydrogenase family
ET471_RS00505	COG1454	alcohol dehydrogenase
ET471_RS00535	COG1505	serine-type exopeptidase activity
ET471_RS00545	COG0482	sulfurtransferase activity
ET471_RS00555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ET471_RS00575	COG0366	Alpha amylase catalytic
ET471_RS00590	COG2252	PERMEase
ET471_RS00595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ET471_RS00625	COG2267	carboxylic ester hydrolase activity
ET471_RS00640	COG0545	Peptidyl-prolyl cis-trans isomerase
ET471_RS00655	COG2814	Major facilitator Superfamily
ET471_RS00670	COG0366	Alpha amylase catalytic
ET471_RS00675	COG0758	DNA mediated transformation
ET471_RS00675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ET471_RS00730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET471_RS00755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ET471_RS00865	COG0739	heme binding
ET471_RS00865	COG0741	lytic transglycosylase activity
ET471_RS00865	COG1196	nuclear chromosome segregation
ET471_RS00895	COG1136	(ABC) transporter
ET471_RS00940	COG3547	Transposase (IS116 IS110 IS902 family)
ET471_RS01025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET471_RS01030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ET471_RS01035	COG1780	Probably involved in ribonucleotide reductase function
ET471_RS01055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ET471_RS01060	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ET471_RS01070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ET471_RS01075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ET471_RS01080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ET471_RS01085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ET471_RS01090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ET471_RS01105	COG0356	it plays a direct role in the translocation of protons across the membrane
ET471_RS01115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ET471_RS01125	COG2890	protein-(glutamine-N5) methyltransferase activity
ET471_RS01130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ET471_RS01135	COG0254	rRNA binding
ET471_RS01140	COG0438	transferase activity, transferring glycosyl groups
ET471_RS01150	COG0083	homoserine kinase activity
ET471_RS01155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ET471_RS01160	COG0460	homoserine dehydrogenase
ET471_RS01170	COG0018	arginyl-trna synthetase
ET471_RS01185	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET471_RS01210	COG2223	nitrite transmembrane transporter activity
ET471_RS01220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ET471_RS01230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ET471_RS01235	COG2079	MmgE PrpD family protein
ET471_RS01240	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ET471_RS01275	COG1253	flavin adenine dinucleotide binding
ET471_RS01280	COG0745	RESPONSE REGULATOR receiver
ET471_RS01285	COG2205	protein histidine kinase activity
ET471_RS01290	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET471_RS01290	COG0567	Dehydrogenase, E1 component
ET471_RS01295	COG0667	Aldo Keto reductase
ET471_RS01320	COG5662	AntiSigma factor
ET471_RS01325	COG1595	DNA-templated transcription, initiation
ET471_RS01340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ET471_RS01345	COG1162	GTPase activity
ET471_RS01350	COG0483	inositol monophosphate 1-phosphatase activity
ET471_RS01395	COG0653	protein targeting
ET471_RS01400	COG3214	Protein conserved in bacteria
ET471_RS01405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ET471_RS01420	COG5002	protein histidine kinase activity
ET471_RS01425	COG0745	RESPONSE REGULATOR receiver
ET471_RS01445	COG0714	Associated with various cellular activities
ET471_RS01470	COG2197	response regulator
ET471_RS01480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ET471_RS01565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ET471_RS01575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ET471_RS01595	COG1216	Glycosyl transferase, family 2
ET471_RS01635	COG2801	Transposase and inactivated derivatives
ET471_RS01685	COG0438	transferase activity, transferring glycosyl groups
ET471_RS01685	COG1216	Glycosyl transferase, family 2
ET471_RS01780	COG1088	dTDP-glucose 4,6-dehydratase activity
ET471_RS01785	COG1316	TRANSCRIPTIONal
ET471_RS01790	COG1316	TRANSCRIPTIONal
ET471_RS01805	COG2205	protein histidine kinase activity
ET471_RS01810	COG0745	RESPONSE REGULATOR receiver
ET471_RS01820	COG2197	response regulator
ET471_RS01825	COG0577	efflux transmembrane transporter activity
ET471_RS01825	COG1136	(ABC) transporter
ET471_RS01870	COG0395	ABC-type sugar transport system, permease component
ET471_RS01875	COG2723	6-phospho-beta-galactosidase activity
ET471_RS01885	COG3459	Glycosyltransferase 36 associated
ET471_RS01890	COG0531	amino acid
ET471_RS01900	COG1012	belongs to the aldehyde dehydrogenase family
ET471_RS01905	COG0656	L-ascorbic acid biosynthetic process
ET471_RS01910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ET471_RS01915	COG2890	protein-(glutamine-N5) methyltransferase activity
ET471_RS01920	COG3253	May function as heme-dependent peroxidase
ET471_RS01925	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ET471_RS01940	COG1929	Belongs to the glycerate kinase type-1 family
ET471_RS01945	COG2409	Drug exporters of the RND superfamily
ET471_RS01955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ET471_RS01965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ET471_RS01975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ET471_RS01985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ET471_RS01990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ET471_RS02010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET471_RS02015	COG1793	dna ligase
ET471_RS02035	COG2813	Specifically methylates the guanine in position
ET471_RS02040	COG1609	Transcriptional regulator
ET471_RS02045	COG1653	transport
ET471_RS02050	COG1175	transmembrane transport
ET471_RS02055	COG0395	ABC-type sugar transport system, permease component
ET471_RS02060	COG1609	Transcriptional regulator
ET471_RS02065	COG1904	glucuronate isomerase
ET471_RS02075	COG1070	Carbohydrate kinase
ET471_RS02080	COG0246	Mannitol dehydrogenase
ET471_RS02085	COG0673	inositol 2-dehydrogenase activity
ET471_RS02105	COG1312	Catalyzes the dehydration of D-mannonate
ET471_RS02110	COG0246	Mannitol dehydrogenase
ET471_RS02125	COG0395	ABC-type sugar transport system, permease component
ET471_RS02130	COG4209	transmembrane transport
ET471_RS02145	COG3387	PFAM Glycoside hydrolase 15-related
ET471_RS02155	COG1131	(ABC) transporter
ET471_RS02170	COG1252	NADH dehydrogenase
ET471_RS02200	COG0148	phosphopyruvate hydratase activity
ET471_RS02210	COG0579	oxidoreductase
ET471_RS02230	COG2755	lipolytic protein G-D-S-L family
ET471_RS02230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ET471_RS02255	COG0438	transferase activity, transferring glycosyl groups
ET471_RS02260	COG3754	Rhamnan synthesis protein F
ET471_RS02275	COG0297	glycogen (starch) synthase activity
ET471_RS02280	COG1215	transferase activity, transferring glycosyl groups
ET471_RS02285	COG1216	Glycosyl transferase, family 2
ET471_RS02285	COG0438	transferase activity, transferring glycosyl groups
ET471_RS02295	COG0297	glycogen (starch) synthase activity
ET471_RS02305	COG1216	Glycosyl transferase, family 2
ET471_RS02310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ET471_RS02315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ET471_RS02355	COG0438	transferase activity, transferring glycosyl groups
ET471_RS02365	COG0438	transferase activity, transferring glycosyl groups
ET471_RS02390	COG0193	aminoacyl-tRNA hydrolase activity
ET471_RS02395	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ET471_RS02400	COG0463	Glycosyl transferase, family 2
ET471_RS02410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ET471_RS02420	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ET471_RS02435	COG4152	abc transporter atp-binding protein
ET471_RS02440	COG1668	transmembrane transport
ET471_RS02445	COG1846	Transcriptional regulator
ET471_RS02455	COG2807	transmembrane transport
ET471_RS02480	COG0488	(ABC) transporter
ET471_RS02485	COG3458	cephalosporin-C deacetylase activity
ET471_RS02490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ET471_RS02520	COG0084	hydrolase, TatD family'
ET471_RS02540	COG1335	isochorismatase
ET471_RS02555	COG0494	nUDIX hydrolase
ET471_RS02595	COG1366	Belongs to the anti-sigma-factor antagonist family
ET471_RS02640	COG1175	transmembrane transport
ET471_RS02690	COG0583	DNA-binding transcription factor activity
ET471_RS02725	COG1172	Belongs to the binding-protein-dependent transport system permease family
ET471_RS02730	COG1129	ABC transporter
ET471_RS02760	COG4585	Histidine kinase
ET471_RS02765	COG2197	response regulator
ET471_RS02835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ET471_RS02855	COG1970	mechanosensitive ion channel activity
ET471_RS02875	COG1136	(ABC) transporter
ET471_RS02875	COG0577	efflux transmembrane transporter activity
ET471_RS02895	COG1940	carbohydrate kinase activity
ET471_RS02900	COG2115	Belongs to the xylose isomerase family
ET471_RS02905	COG1070	Carbohydrate kinase
ET471_RS02945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET471_RS02955	COG0791	NLP P60 protein
ET471_RS02960	COG3103	Sh3 type 3 domain protein
ET471_RS02960	COG1388	LysM domain
ET471_RS02960	COG0791	NLP P60 protein
ET471_RS02975	COG2814	Major facilitator Superfamily
ET471_RS02980	COG2814	Major facilitator Superfamily
ET471_RS02995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ET471_RS03030	COG1487	ribonuclease activity
ET471_RS03040	COG2252	PERMEase
ET471_RS03045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ET471_RS03070	COG1278	Cold shock
ET471_RS03080	COG1061	Type III restriction enzyme res subunit
ET471_RS03090	COG1842	Phage shock protein A
ET471_RS03105	COG0745	RESPONSE REGULATOR receiver
ET471_RS03110	COG2205	protein histidine kinase activity
ET471_RS03125	COG0459	protein refolding
ET471_RS03140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ET471_RS03180	COG3842	ATPase activity
ET471_RS03190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET471_RS03195	COG0215	cysteine-tRNA ligase activity
ET471_RS03215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ET471_RS03220	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ET471_RS03225	COG1329	Transcriptional regulator
ET471_RS03235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET471_RS03255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ET471_RS03260	COG0581	inorganic phosphate transmembrane transporter activity
ET471_RS03270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ET471_RS03275	COG0745	RESPONSE REGULATOR receiver
ET471_RS03295	COG0297	glycogen (starch) synthase activity
ET471_RS03310	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ET471_RS03330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ET471_RS03340	COG0302	gtp cyclohydrolase
ET471_RS03345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ET471_RS03350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ET471_RS03355	COG0037	tRNA processing
ET471_RS03370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ET471_RS03390	COG2873	o-acetylhomoserine
ET471_RS03395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ET471_RS03410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET471_RS03420	COG0604	alcohol dehydrogenase
ET471_RS03440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ET471_RS03445	COG1920	GTP binding
ET471_RS03470	COG1764	response to oxidative stress
ET471_RS03525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ET471_RS03530	COG3485	protocatechuate 3,4-dioxygenase
ET471_RS03545	COG2353	YceI-like domain
ET471_RS03555	COG0745	RESPONSE REGULATOR receiver
ET471_RS03560	COG0596	Alpha beta hydrolase
ET471_RS03590	COG1408	metallophosphoesterase
ET471_RS03675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ET471_RS03680	COG2816	NAD+ diphosphatase activity
ET471_RS03700	COG3655	Transcriptional regulator
ET471_RS03725	COG0584	glycerophosphoryl diester phosphodiesterase
ET471_RS03740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ET471_RS03785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ET471_RS03800	COG0737	Belongs to the 5'-nucleotidase family
ET471_RS03815	COG2116	formate transmembrane transporter activity
ET471_RS03835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ET471_RS03845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS03865	COG0477	Major facilitator Superfamily
ET471_RS03875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS03885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET471_RS03895	COG1126	abc transporter atp-binding protein
ET471_RS03910	COG4172	Belongs to the ABC transporter superfamily
ET471_RS03915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET471_RS03920	COG0601	transmembrane transport
ET471_RS03925	COG0747	negative chemotaxis
ET471_RS03930	COG2838	Isocitrate dehydrogenase
ET471_RS03960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ET471_RS03990	COG0183	Belongs to the thiolase family
ET471_RS04000	COG2030	dehydratase
ET471_RS04005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS04010	COG0154	amidase activity
ET471_RS04015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ET471_RS04055	COG0535	radical SAM domain protein
ET471_RS04060	COG0047	phosphoribosylformylglycinamidine synthase activity
ET471_RS04065	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ET471_RS04095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ET471_RS04100	COG0151	Belongs to the GarS family
ET471_RS04105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ET471_RS04135	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ET471_RS04140	COG0586	Pfam SNARE associated Golgi protein
ET471_RS04150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ET471_RS04155	COG0598	Magnesium transport protein CorA
ET471_RS04160	COG4221	oxidoreductase activity
ET471_RS04170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET471_RS04175	COG0601	transmembrane transport
ET471_RS04180	COG0747	negative chemotaxis
ET471_RS04185	COG0708	Exodeoxyribonuclease III
ET471_RS04210	COG2169	Transcriptional regulator
ET471_RS04210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ET471_RS04230	COG0651	ATP synthesis coupled electron transport
ET471_RS04240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ET471_RS04240	COG2111	Na H antiporter
ET471_RS04250	COG0717	Belongs to the dCTP deaminase family
ET471_RS04275	COG1309	transcriptional regulator
ET471_RS04285	COG2909	trisaccharide binding
ET471_RS04300	COG1082	Xylose isomerase domain protein TIM barrel
ET471_RS04305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ET471_RS04310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ET471_RS04315	COG2190	(PTS) system
ET471_RS04325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ET471_RS04340	COG2755	lipolytic protein G-D-S-L family
ET471_RS04340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ET471_RS04360	COG0656	L-ascorbic acid biosynthetic process
ET471_RS04385	COG2409	Drug exporters of the RND superfamily
ET471_RS04400	COG3336	cytochrome c oxidase
ET471_RS04405	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET471_RS04410	COG0022	dehydrogenase e1 component
ET471_RS04420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ET471_RS04425	COG1950	PFAM Membrane protein of
ET471_RS04440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ET471_RS04480	COG0248	Ppx GppA phosphatase
ET471_RS04490	COG0395	ABC-type sugar transport system, permease component
ET471_RS04495	COG1175	transmembrane transport
ET471_RS04500	COG1653	transport
ET471_RS04520	COG0561	phosphatase activity
ET471_RS04525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ET471_RS04530	COG1597	lipid kinase activity
ET471_RS04540	COG1215	transferase activity, transferring glycosyl groups
ET471_RS04550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ET471_RS04555	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ET471_RS04560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ET471_RS04585	COG0113	porphobilinogen synthase activity
ET471_RS04590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ET471_RS04600	COG1937	Protein conserved in bacteria
ET471_RS04675	COG2197	response regulator
ET471_RS04690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ET471_RS04695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ET471_RS04700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ET471_RS04710	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ET471_RS04715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET471_RS04745	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ET471_RS04775	COG1966	Carbon starvation protein
ET471_RS04795	COG0601	transmembrane transport
ET471_RS04800	COG2318	DinB family
ET471_RS04815	COG0251	oxidation-reduction process
ET471_RS04825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ET471_RS04835	COG2423	ornithine cyclodeaminase activity
ET471_RS04840	COG1834	amidinotransferase
ET471_RS04865	COG0477	Major facilitator Superfamily
ET471_RS04870	COG1335	isochorismatase
ET471_RS04905	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ET471_RS04940	COG0346	lactoylglutathione lyase activity
ET471_RS04975	COG0456	acetyltransferase
ET471_RS04985	COG1309	transcriptional regulator
ET471_RS04990	COG1132	(ABC) transporter
ET471_RS05020	COG2197	response regulator
ET471_RS05065	COG2732	(Barnase) inhibitor
ET471_RS05070	COG0305	Participates in initiation and elongation during chromosome replication
ET471_RS05080	COG0359	binds to the 23S rRNA
ET471_RS05085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ET471_RS05095	COG0360	Binds together with S18 to 16S ribosomal RNA
ET471_RS05100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET471_RS05105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET471_RS05110	COG1695	Transcriptional regulator
ET471_RS05115	COG1260	myo-inositol-1-phosphate synthase
ET471_RS05135	COG0438	transferase activity, transferring glycosyl groups
ET471_RS05210	COG2814	Major facilitator Superfamily
ET471_RS05215	COG0617	tRNA 3'-terminal CCA addition
ET471_RS05240	COG0492	ferredoxin-NADP+ reductase activity
ET471_RS05245	COG3118	belongs to the thioredoxin family
ET471_RS05250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET471_RS05255	COG1181	Belongs to the D-alanine--D-alanine ligase family
ET471_RS05270	COG1192	Involved in chromosome partitioning
ET471_RS05275	COG0357	Ribosomal RNA small subunit methyltransferase G
ET471_RS05285	COG0706	membrane insertase activity
ET471_RS05290	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ET471_RS05295	COG0594	ribonuclease P activity
ET471_RS05300	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ET471_RS05305	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ET471_RS05310	COG0592	DNA-directed DNA polymerase activity
ET471_RS05315	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ET471_RS05320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ET471_RS05325	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ET471_RS05330	COG0187	DNA topoisomerase II activity
ET471_RS05335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ET471_RS05360	COG1131	(ABC) transporter
ET471_RS05400	COG3764	Sortase (surface protein transpeptidase)
ET471_RS05420	COG0515	serine threonine protein kinase
ET471_RS05425	COG0768	penicillin binding
ET471_RS05440	COG1716	ATPase activity
ET471_RS05480	COG2149	membrane
ET471_RS05485	COG0702	epimerase
ET471_RS05490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ET471_RS05505	COG0436	Aminotransferase
ET471_RS05515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ET471_RS05540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ET471_RS05545	COG0509	glycine decarboxylation via glycine cleavage system
ET471_RS05550	COG2197	response regulator
ET471_RS05555	COG0494	nUDIX hydrolase
ET471_RS05560	COG0738	Major facilitator superfamily
ET471_RS05580	COG0318	PFAM AMP-dependent synthetase and ligase
ET471_RS05580	COG0204	Acyl-transferase
ET471_RS05595	COG2818	Glycosylase
ET471_RS05620	COG1609	Transcriptional regulator
ET471_RS05625	COG0366	Alpha amylase catalytic
ET471_RS05630	COG1653	transport
ET471_RS05635	COG4209	transmembrane transport
ET471_RS05640	COG0395	ABC-type sugar transport system, permease component
ET471_RS05655	COG1643	Atp-dependent helicase
ET471_RS05660	COG4585	Histidine kinase
ET471_RS05670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ET471_RS05680	COG2376	Dihydroxyacetone kinase
ET471_RS05685	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ET471_RS05690	COG1984	allophanate hydrolase subunit 2
ET471_RS05695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ET471_RS05730	COG0765	amino acid transport
ET471_RS05735	COG1126	abc transporter atp-binding protein
ET471_RS05760	COG1278	Cold shock
ET471_RS05830	COG4977	sequence-specific DNA binding
ET471_RS05850	COG3012	SEC-C Motif Domain Protein
ET471_RS05855	COG2814	Major facilitator Superfamily
ET471_RS05875	COG2837	iron assimilation
ET471_RS05885	COG2217	Heavy metal translocating P-type atpase
ET471_RS05890	COG0791	NLP P60 protein
ET471_RS05930	COG2329	Antibiotic biosynthesis monooxygenase
ET471_RS05940	COG1022	Amp-dependent synthetase and ligase
ET471_RS05950	COG3123	guanosine phosphorylase activity
ET471_RS05965	COG4702	Belongs to the UPF0303 family
ET471_RS05990	COG2201	protein-glutamate methylesterase activity
ET471_RS06030	COG0659	secondary active sulfate transmembrane transporter activity
ET471_RS06070	COG0577	efflux transmembrane transporter activity
ET471_RS06070	COG1136	(ABC) transporter
ET471_RS06110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ET471_RS06115	COG0300	oxidoreductase activity
ET471_RS06125	COG0406	alpha-ribazole phosphatase activity
ET471_RS06140	COG3550	peptidyl-serine autophosphorylation
ET471_RS06150	COG0328	RNA-DNA hybrid ribonuclease activity
ET471_RS06190	COG1053	succinate dehydrogenase
ET471_RS06195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ET471_RS06230	COG2018	Roadblock/LC7 domain
ET471_RS06275	COG4143	(ABC) transporter
ET471_RS06285	COG3842	ATPase activity
ET471_RS06300	COG0166	Belongs to the GPI family
ET471_RS06320	COG1609	Transcriptional regulator
ET471_RS06330	COG1175	transmembrane transport
ET471_RS06340	COG1472	Belongs to the glycosyl hydrolase 3 family
ET471_RS06370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET471_RS06390	COG0443	Heat shock 70 kDa protein
ET471_RS06400	COG0484	heat shock protein binding
ET471_RS06420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ET471_RS06425	COG0590	tRNA wobble adenosine to inosine editing
ET471_RS06435	COG1132	(ABC) transporter
ET471_RS06440	COG2239	Acts as a magnesium transporter
ET471_RS06450	COG2197	response regulator
ET471_RS06645	COG2318	DinB family
ET471_RS06650	COG2197	response regulator
ET471_RS06690	COG0438	transferase activity, transferring glycosyl groups
ET471_RS06695	COG0438	transferase activity, transferring glycosyl groups
ET471_RS06710	COG1960	acyl-CoA dehydrogenase activity
ET471_RS06720	COG3201	nicotinamide mononucleotide transporter
ET471_RS06725	COG1309	transcriptional regulator
ET471_RS06730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ET471_RS06750	COG2233	PERMEase
ET471_RS06785	COG1464	Belongs to the NlpA lipoprotein family
ET471_RS06790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ET471_RS06795	COG2011	ABC-type metal ion transport system permease component
ET471_RS06820	COG4166	transmembrane transport
ET471_RS06825	COG0601	transmembrane transport
ET471_RS06835	COG0444	Belongs to the ABC transporter superfamily
ET471_RS06840	COG4172	Belongs to the ABC transporter superfamily
ET471_RS06860	COG0598	Magnesium transport protein CorA
ET471_RS06870	COG1136	(ABC) transporter
ET471_RS06870	COG0577	efflux transmembrane transporter activity
ET471_RS06875	COG1136	(ABC) transporter
ET471_RS06875	COG0577	efflux transmembrane transporter activity
ET471_RS06890	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ET471_RS06915	COG2329	Antibiotic biosynthesis monooxygenase
ET471_RS06940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET471_RS06975	COG0513	Belongs to the DEAD box helicase family
ET471_RS06980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ET471_RS07010	COG0306	phosphate transporter
ET471_RS07015	COG0494	nUDIX hydrolase
ET471_RS07015	COG0406	alpha-ribazole phosphatase activity
ET471_RS07020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ET471_RS07025	COG0456	acetyltransferase
ET471_RS07030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ET471_RS07035	COG1902	pentaerythritol trinitrate reductase activity
ET471_RS07090	COG1205	dead DEAH box helicase
ET471_RS07090	COG1111	helicase
ET471_RS07100	COG1362	aminopeptidase activity
ET471_RS07105	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ET471_RS07110	COG2318	DinB family
ET471_RS07135	COG1754	DNA topoisomerase type I activity
ET471_RS07135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ET471_RS07145	COG1136	(ABC) transporter
ET471_RS07215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ET471_RS07245	COG0242	peptide deformylase activity
ET471_RS07275	COG1175	transmembrane transport
ET471_RS07280	COG0395	ABC-type sugar transport system, permease component
ET471_RS07290	COG0546	phosphoglycolate phosphatase activity
ET471_RS07305	COG1609	Transcriptional regulator
ET471_RS07310	COG4209	transmembrane transport
ET471_RS07315	COG0395	ABC-type sugar transport system, permease component
ET471_RS07330	COG1609	Transcriptional regulator
ET471_RS07345	COG2186	Transcriptional regulator
ET471_RS07360	COG0667	Aldo Keto reductase
ET471_RS07375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ET471_RS07380	COG2354	Protein conserved in bacteria
ET471_RS07385	COG0446	pyridine nucleotide-disulphide oxidoreductase
ET471_RS07400	COG1215	transferase activity, transferring glycosyl groups
ET471_RS07410	COG2909	trisaccharide binding
ET471_RS07415	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ET471_RS07455	COG2814	Major facilitator Superfamily
ET471_RS07470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ET471_RS07475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ET471_RS07480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ET471_RS07495	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ET471_RS07510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ET471_RS07515	COG1609	Transcriptional regulator
ET471_RS07550	COG2160	L-arabinose isomerase activity
ET471_RS07565	COG1131	(ABC) transporter
ET471_RS07575	COG0569	domain protein
ET471_RS07580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ET471_RS07585	COG0123	including yeast histone deacetylase and acetoin utilization protein
ET471_RS07590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS07610	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ET471_RS07625	COG0406	alpha-ribazole phosphatase activity
ET471_RS07635	COG0785	Cytochrome C biogenesis protein
ET471_RS07640	COG1333	cytochrome c biogenesis protein
ET471_RS07645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ET471_RS07670	COG1470	cell adhesion involved in biofilm formation
ET471_RS07675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ET471_RS07680	COG4948	Mandelate Racemase Muconate Lactonizing
ET471_RS07685	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ET471_RS07695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET471_RS07720	COG0534	Mate efflux family protein
ET471_RS07725	COG1169	isochorismate synthase
ET471_RS07730	COG2226	methyltransferase
ET471_RS07745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ET471_RS07750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ET471_RS07755	COG0649	NAD binding
ET471_RS07765	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ET471_RS07770	COG1034	ATP synthesis coupled electron transport
ET471_RS07775	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ET471_RS07780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ET471_RS07790	COG0713	ATP synthesis coupled electron transport
ET471_RS07795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ET471_RS07805	COG1007	ATP synthesis coupled electron transport
ET471_RS07810	COG0142	geranyltranstransferase activity
ET471_RS07820	COG0714	Associated with various cellular activities
ET471_RS07860	COG1674	ftsk spoiiie
ET471_RS07910	COG0501	Belongs to the peptidase M48B family
ET471_RS07915	COG0561	phosphatase activity
ET471_RS07920	COG1666	GTP binding
ET471_RS08420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ET471_RS08425	COG2030	dehydratase
ET471_RS08440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ET471_RS08455	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET471_RS08460	COG2197	response regulator
ET471_RS08465	COG4585	Histidine kinase
ET471_RS08470	COG0842	Transport permease protein
ET471_RS08495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ET471_RS08500	COG0081	regulation of translation
ET471_RS08520	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ET471_RS08525	COG0222	ribosome binding
ET471_RS08530	COG0085	RNA polymerase activity
ET471_RS08535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ET471_RS08540	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ET471_RS08545	COG0049	tRNA binding
ET471_RS08550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ET471_RS08555	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ET471_RS08560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET471_RS08565	COG0051	transcription antitermination factor activity, RNA binding
ET471_RS08570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ET471_RS08575	COG0088	Forms part of the polypeptide exit tunnel
ET471_RS08580	COG0089	rRNA binding
ET471_RS08585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ET471_RS08590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ET471_RS08595	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ET471_RS08600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ET471_RS08605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ET471_RS08610	COG0255	Belongs to the universal ribosomal protein uL29 family
ET471_RS08615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ET471_RS08620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ET471_RS08625	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ET471_RS08630	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ET471_RS08635	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ET471_RS08640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ET471_RS08645	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ET471_RS08655	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ET471_RS08660	COG1841	ribosomal large subunit assembly
ET471_RS08665	COG0200	Binds to the 23S rRNA
ET471_RS08675	COG0563	adenylate kinase activity
ET471_RS08685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ET471_RS08690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ET471_RS08695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ET471_RS08700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ET471_RS08705	COG0202	RNA polymerase activity
ET471_RS08710	COG0203	ribosomal protein L17
ET471_RS08720	COG0101	tRNA pseudouridine synthase activity
ET471_RS08735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ET471_RS08740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ET471_RS08750	COG0242	peptide deformylase activity
ET471_RS08760	COG1072	(Pantothenic acid kinase))
ET471_RS08770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ET471_RS08775	COG0736	holo-[acyl-carrier-protein] synthase activity
ET471_RS08780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS08800	COG0386	Belongs to the glutathione peroxidase family
ET471_RS08805	COG0564	pseudouridine synthase activity
ET471_RS08815	COG0802	atpase or kinase
ET471_RS08820	COG1214	PFAM Peptidase M22, glycoprotease
ET471_RS08820	COG0456	acetyltransferase
ET471_RS08825	COG0456	acetyltransferase
ET471_RS08835	COG0778	Nitroreductase
ET471_RS08840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ET471_RS08850	COG1131	(ABC) transporter
ET471_RS08860	COG1595	DNA-templated transcription, initiation
ET471_RS08870	COG0477	Major facilitator Superfamily
ET471_RS08890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ET471_RS08915	COG0516	GMP reductase activity
ET471_RS08930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ET471_RS08955	COG2514	catechol 2,3-dioxygenase activity
ET471_RS08965	COG1132	(ABC) transporter
ET471_RS08970	COG1132	(ABC) transporter
ET471_RS08985	COG1136	(ABC) transporter
ET471_RS08985	COG0577	efflux transmembrane transporter activity
ET471_RS09000	COG0519	Catalyzes the synthesis of GMP from XMP
ET471_RS09000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ET471_RS09025	COG2197	response regulator
ET471_RS09030	COG1648	precorrin-2 dehydrogenase activity
ET471_RS09030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ET471_RS09035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET471_RS09060	COG0175	sulfate reduction
ET471_RS09065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET471_RS09070	COG2855	membrane
ET471_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS09120	COG0045	succinate-CoA ligase (ADP-forming) activity
ET471_RS09205	COG1846	Transcriptional regulator
ET471_RS09205	COG1940	carbohydrate kinase activity
ET471_RS09220	COG4214	carbohydrate transport
ET471_RS09225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ET471_RS09230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ET471_RS09245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ET471_RS09265	COG2239	Acts as a magnesium transporter
ET471_RS09275	COG0006	proline dipeptidase activity
ET471_RS09285	COG0613	PHP domain protein
ET471_RS09290	COG2095	MarC family integral membrane protein
ET471_RS09300	COG0513	Belongs to the DEAD box helicase family
ET471_RS09335	COG2816	NAD+ diphosphatase activity
ET471_RS09385	COG1615	UPF0182 protein
ET471_RS09400	COG1120	ATPase activity
ET471_RS09415	COG1253	flavin adenine dinucleotide binding
ET471_RS09420	COG0803	Belongs to the bacterial solute-binding protein 9 family
ET471_RS09440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ET471_RS09445	COG0025	NhaP-type Na H and K H
ET471_RS09450	COG2720	vancomycin resistance protein
ET471_RS09455	COG1609	Transcriptional regulator
ET471_RS09465	COG4952	isomerase
ET471_RS09470	COG3347	Dehydrogenase
ET471_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS09475	COG1609	Transcriptional regulator
ET471_RS09480	COG3401	FG-GAP repeat protein
ET471_RS09485	COG1556	Lactate utilization protein
ET471_RS09490	COG1139	Iron-sulfur cluster binding protein
ET471_RS09495	COG0247	lactate metabolic process
ET471_RS09500	COG0673	inositol 2-dehydrogenase activity
ET471_RS09505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ET471_RS09515	COG1116	anion transmembrane transporter activity
ET471_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS09525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ET471_RS09535	COG0673	inositol 2-dehydrogenase activity
ET471_RS09545	COG1175	transmembrane transport
ET471_RS09550	COG0395	ABC-type sugar transport system, permease component
ET471_RS09560	COG3534	alpha-L-arabinofuranosidase
ET471_RS09580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ET471_RS09610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ET471_RS09620	COG3833	ABC-type maltose transport systems, permease component
ET471_RS09625	COG1175	transmembrane transport
ET471_RS09630	COG2182	Extracellular solute-binding protein
ET471_RS09665	COG1175	transmembrane transport
ET471_RS09670	COG0395	ABC-type sugar transport system, permease component
ET471_RS09685	COG0179	Fumarylacetoacetate (FAA) hydrolase
ET471_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS09710	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ET471_RS09715	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ET471_RS09720	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ET471_RS09770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ET471_RS09785	COG3177	Filamentation induced by cAMP protein fic
ET471_RS09790	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ET471_RS09800	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ET471_RS09815	COG0601	transmembrane transport
ET471_RS09845	COG0114	fumarate hydratase activity
ET471_RS09855	COG1722	exodeoxyribonuclease VII activity
ET471_RS09860	COG0488	(ABC) transporter
ET471_RS09865	COG0385	Bile acid
ET471_RS09870	COG1570	exodeoxyribonuclease VII activity
ET471_RS09875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ET471_RS09880	COG1322	Protein conserved in bacteria
ET471_RS09900	COG0012	GTP binding
ET471_RS09910	COG0747	negative chemotaxis
ET471_RS09920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET471_RS09925	COG0444	Belongs to the ABC transporter superfamily
ET471_RS09930	COG4608	Belongs to the ABC transporter superfamily
ET471_RS09965	COG4172	Belongs to the ABC transporter superfamily
ET471_RS09970	COG1217	gtp-binding protein TYPA
ET471_RS09975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ET471_RS09995	COG0077	Prephenate dehydratase
ET471_RS10000	COG0287	Prephenate dehydrogenase
ET471_RS10040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ET471_RS10045	COG1611	Belongs to the LOG family
ET471_RS10050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ET471_RS10065	COG1595	DNA-templated transcription, initiation
ET471_RS10080	COG0180	Tryptophanyl-tRNA synthetase
ET471_RS10100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ET471_RS10105	COG1053	succinate dehydrogenase
ET471_RS10115	COG2009	succinate dehydrogenase
ET471_RS10125	COG1744	ABC transporter substrate-binding protein PnrA-like
ET471_RS10135	COG4603	Belongs to the binding-protein-dependent transport system permease family
ET471_RS10140	COG1079	Belongs to the binding-protein-dependent transport system permease family
ET471_RS10165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET471_RS10170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ET471_RS10185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET471_RS10205	COG2837	iron assimilation
ET471_RS10215	COG0672	)-iron permease
ET471_RS10240	COG4770	biotin carboxylase activity
ET471_RS10245	COG0424	maF-like protein
ET471_RS10270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ET471_RS10300	COG2135	peptidase activity
ET471_RS10335	COG1316	TRANSCRIPTIONal
ET471_RS10425	COG1061	Type III restriction enzyme res subunit
ET471_RS10440	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ET471_RS10445	COG2884	Cell division ATP-binding protein ftsE
ET471_RS10450	COG2177	Part of the ABC transporter FtsEX involved in
ET471_RS10455	COG0739	heme binding
ET471_RS10460	COG0739	heme binding
ET471_RS10465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ET471_RS10480	COG0569	domain protein
ET471_RS10480	COG0475	glutathione-regulated potassium exporter activity
ET471_RS10485	COG1940	carbohydrate kinase activity
ET471_RS10485	COG1846	Transcriptional regulator
ET471_RS10495	COG1175	transmembrane transport
ET471_RS10500	COG0395	ABC-type sugar transport system, permease component
ET471_RS10510	COG0363	glucosamine-6-phosphate deaminase activity
ET471_RS10525	COG3559	Exporter of polyketide antibiotics
ET471_RS10530	COG1131	(ABC) transporter
ET471_RS10550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ET471_RS10570	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ET471_RS10580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ET471_RS10585	COG1234	tRNA 3'-trailer cleavage
ET471_RS10595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ET471_RS10600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ET471_RS10605	COG0488	(ABC) transporter
ET471_RS10615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ET471_RS10620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET471_RS10625	COG0747	negative chemotaxis
ET471_RS10640	COG4608	Belongs to the ABC transporter superfamily
ET471_RS10710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ET471_RS10720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ET471_RS10725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ET471_RS10735	COG1174	glycine betaine transport
ET471_RS10745	COG1125	glycine betaine transport
ET471_RS10745	COG0517	IMP dehydrogenase activity
ET471_RS10780	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ET471_RS10785	COG0481	GTPase activity
ET471_RS10850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ET471_RS10855	COG0668	transmembrane transport
ET471_RS10875	COG3590	peptidase
ET471_RS10895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS10910	COG1045	serine acetyltransferase
ET471_RS11025	COG1136	(ABC) transporter
ET471_RS11045	COG1132	(ABC) transporter
ET471_RS11050	COG0544	peptidyl-prolyl cis-trans isomerase activity
ET471_RS11060	COG0740	serine-type endopeptidase activity
ET471_RS11065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ET471_RS11070	COG1022	Amp-dependent synthetase and ligase
ET471_RS11075	COG1605	Chorismate mutase
ET471_RS11075	COG0287	Prephenate dehydrogenase
ET471_RS11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET471_RS11095	COG0765	amino acid transport
ET471_RS11100	COG1126	abc transporter atp-binding protein
ET471_RS11115	COG0778	Nitroreductase
ET471_RS11115	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ET471_RS11155	COG0395	ABC-type sugar transport system, permease component
ET471_RS11185	COG1695	Transcriptional regulator
ET471_RS11195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ET471_RS11200	COG0577	efflux transmembrane transporter activity
ET471_RS11200	COG1136	(ABC) transporter
ET471_RS11205	COG1136	(ABC) transporter
ET471_RS11205	COG0577	efflux transmembrane transporter activity
ET471_RS11210	COG4585	Histidine kinase
ET471_RS11220	COG0285	dihydrofolate synthase activity
ET471_RS11225	COG2376	Dihydroxyacetone kinase
ET471_RS11230	COG1461	Dihydroxyacetone kinase
ET471_RS11245	COG0477	Major facilitator Superfamily
ET471_RS11255	COG0105	UTP biosynthetic process
ET471_RS11285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ET471_RS11300	COG0228	four-way junction DNA binding
ET471_RS11305	COG1837	Belongs to the UPF0109 family
ET471_RS11310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ET471_RS11315	COG0336	Belongs to the RNA methyltransferase TrmD family
ET471_RS11320	COG0335	large ribosomal subunit rRNA binding
ET471_RS11335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ET471_RS11345	COG0792	nuclease activity
ET471_RS11360	COG4974	Belongs to the 'phage' integrase family
ET471_RS11370	COG0052	Belongs to the universal ribosomal protein uS2 family
ET471_RS11375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ET471_RS11385	COG0233	cytoplasmic translational termination
ET471_RS11390	COG0575	Belongs to the CDS family
ET471_RS11395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ET471_RS11420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ET471_RS11425	COG0351	phosphomethylpyrimidine kinase
ET471_RS11430	COG0352	thiamine-phosphate diphosphorylase activity
ET471_RS11435	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ET471_RS11445	COG0750	zinc metalloprotease
ET471_RS11450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ET471_RS11465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET471_RS11480	COG0779	Required for maturation of 30S ribosomal subunits
ET471_RS11495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ET471_RS11505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ET471_RS11520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ET471_RS11530	COG0612	Peptidase, M16
ET471_RS11535	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ET471_RS11555	COG0456	acetyltransferase
ET471_RS11580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ET471_RS11585	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ET471_RS11610	COG1674	ftsk spoiiie
ET471_RS11625	COG1058	Belongs to the CinA family
ET471_RS11625	COG1546	Belongs to the CinA family
ET471_RS11630	COG1396	sequence-specific DNA binding
ET471_RS11635	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET471_RS11650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ET471_RS11655	COG2137	regulation of response to DNA damage stimulus
ET471_RS11660	COG0765	amino acid transport
ET471_RS11665	COG0765	amino acid transport
ET471_RS11670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ET471_RS11675	COG1126	abc transporter atp-binding protein
ET471_RS11680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ET471_RS11710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ET471_RS11715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ET471_RS11725	COG2813	Specifically methylates the guanine in position
ET471_RS11730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ET471_RS11745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ET471_RS11750	COG1388	LysM domain
ET471_RS11755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ET471_RS11760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ET471_RS11775	COG4251	negative regulation of phosphorylation
ET471_RS11780	COG0784	Response regulator, receiver
ET471_RS11790	COG1278	Cold shock
ET471_RS11805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ET471_RS11825	COG0714	Associated with various cellular activities
ET471_RS11830	COG2001	Belongs to the MraZ family
ET471_RS11835	COG0275	rRNA processing
ET471_RS11845	COG0768	penicillin binding
ET471_RS11850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ET471_RS11855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ET471_RS11860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ET471_RS11865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ET471_RS11875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ET471_RS11880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ET471_RS11890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ET471_RS11900	COG1799	cell septum assembly
ET471_RS11920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ET471_RS11935	COG0587	DNA-directed DNA polymerase activity
ET471_RS11950	COG2501	S4 domain
ET471_RS11955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ET471_RS12005	COG0131	Imidazoleglycerol-phosphate dehydratase
ET471_RS12015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ET471_RS12020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ET471_RS12050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ET471_RS12055	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ET471_RS12060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ET471_RS12065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ET471_RS12085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ET471_RS12095	COG4106	trans-aconitate 2-methyltransferase activity
ET471_RS12110	COG2226	methyltransferase
ET471_RS12115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ET471_RS12120	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ET471_RS12125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ET471_RS12130	COG0586	Pfam SNARE associated Golgi protein
ET471_RS12135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ET471_RS12145	COG1438	arginine binding
ET471_RS12160	COG2094	Belongs to the DNA glycosylase MPG family
ET471_RS12165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ET471_RS12190	COG0647	UMP catabolic process
ET471_RS12225	COG0497	DNA recombination
ET471_RS12250	COG0504	CTP synthase activity
ET471_RS12255	COG0494	nUDIX hydrolase
ET471_RS12320	COG0719	Fe-S assembly protein
ET471_RS12330	COG0396	ATPase activity
ET471_RS12340	COG0822	iron-sulfur transferase activity
ET471_RS12345	COG2151	metal-sulfur cluster biosynthetic enzyme
ET471_RS12430	COG0577	efflux transmembrane transporter activity
ET471_RS12430	COG1136	(ABC) transporter
ET471_RS12500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ET471_RS12510	COG0457	Tetratricopeptide repeat
ET471_RS12515	COG2017	converts alpha-aldose to the beta-anomer
ET471_RS12520	COG1175	transmembrane transport
ET471_RS12525	COG0395	ABC-type sugar transport system, permease component
ET471_RS12570	COG3833	ABC-type maltose transport systems, permease component
ET471_RS12595	COG2205	protein histidine kinase activity
ET471_RS12600	COG0745	RESPONSE REGULATOR receiver
ET471_RS12620	COG3250	beta-galactosidase activity
ET471_RS12625	COG0395	ABC-type sugar transport system, permease component
ET471_RS12630	COG1175	transmembrane transport
ET471_RS12635	COG1653	transport
ET471_RS12680	COG4608	Belongs to the ABC transporter superfamily
ET471_RS12685	COG0444	Belongs to the ABC transporter superfamily
ET471_RS12690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET471_RS12695	COG0601	transmembrane transport
ET471_RS12705	COG4166	transmembrane transport
ET471_RS12710	COG0783	Belongs to the Dps family
ET471_RS12725	COG0454	-acetyltransferase
ET471_RS12725	COG0456	acetyltransferase
ET471_RS12730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ET471_RS12735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ET471_RS12735	COG4499	WXG100 protein secretion system (Wss), protein YukC
ET471_RS12760	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS12780	COG1695	Transcriptional regulator
ET471_RS12795	COG0488	(ABC) transporter
ET471_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS12845	COG0297	glycogen (starch) synthase activity
ET471_RS12855	COG0745	RESPONSE REGULATOR receiver
ET471_RS12860	COG2205	protein histidine kinase activity
ET471_RS12870	COG1119	ATPase activity
ET471_RS12915	COG1733	regulation of RNA biosynthetic process
ET471_RS12950	COG0587	DNA-directed DNA polymerase activity
ET471_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS12985	COG0583	DNA-binding transcription factor activity
ET471_RS13030	COG1309	transcriptional regulator
ET471_RS13040	COG1988	membrane-bound metal-dependent
ET471_RS13055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ET471_RS13075	COG0657	acetylesterase activity
ET471_RS13085	COG0395	ABC-type sugar transport system, permease component
ET471_RS13090	COG4209	transmembrane transport
ET471_RS13100	COG1609	Transcriptional regulator
ET471_RS13110	COG3534	alpha-L-arabinofuranosidase
ET471_RS13125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ET471_RS13130	COG0488	(ABC) transporter
ET471_RS13140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ET471_RS13155	COG0667	Aldo Keto reductase
ET471_RS13165	COG0215	cysteine-tRNA ligase activity
ET471_RS13185	COG1994	Peptidase M50
ET471_RS13185	COG0517	IMP dehydrogenase activity
ET471_RS13195	COG1222	aaa ATPase
ET471_RS13210	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ET471_RS13215	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ET471_RS13220	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ET471_RS13230	COG0107	imidazoleglycerol-phosphate synthase activity
ET471_RS13235	COG1132	(ABC) transporter
ET471_RS13240	COG1132	(ABC) transporter
ET471_RS13265	COG0134	indole-3-glycerol-phosphate synthase activity
ET471_RS13270	COG0133	tryptophan synthase activity
ET471_RS13275	COG0159	tryptophan synthase activity
ET471_RS13280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ET471_RS13285	COG0067	glutamate synthase
ET471_RS13285	COG0069	glutamate synthase activity
ET471_RS13285	COG0070	glutamate synthase
ET471_RS13350	COG0539	negative regulation of cytoplasmic translation
ET471_RS13360	COG1090	epimerase
ET471_RS13370	COG1132	(ABC) transporter
ET471_RS13380	COG0237	dephospho-CoA kinase activity
ET471_RS13380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ET471_RS13385	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ET471_RS13390	COG0556	nucleotide-excision repair
ET471_RS13415	COG2267	carboxylic ester hydrolase activity
ET471_RS13440	COG0322	excinuclease ABC activity
ET471_RS13455	COG1481	regulation of sporulation
ET471_RS13460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ET471_RS13465	COG0126	phosphoglycerate kinase activity
ET471_RS13470	COG0149	triose-phosphate isomerase activity
ET471_RS13475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ET471_RS13485	COG0363	glucosamine-6-phosphate deaminase activity
ET471_RS13500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ET471_RS13510	COG0109	protoheme IX farnesyltransferase activity
ET471_RS13535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ET471_RS13540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ET471_RS13550	COG1160	GTP binding
ET471_RS13575	COG1660	Displays ATPase and GTPase activities
ET471_RS13585	COG0390	transport system, permease component
ET471_RS13590	COG5002	protein histidine kinase activity
ET471_RS13595	COG0745	RESPONSE REGULATOR receiver
ET471_RS13600	COG1968	undecaprenyl-diphosphatase activity
ET471_RS13650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ET471_RS13675	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS13680	COG0183	Belongs to the thiolase family
ET471_RS13690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ET471_RS13705	COG1960	acyl-CoA dehydrogenase activity
ET471_RS13715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ET471_RS13720	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET471_RS13725	COG0022	dehydrogenase e1 component
ET471_RS13765	COG0640	Transcriptional regulator
ET471_RS13770	COG2226	methyltransferase
ET471_RS13780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ET471_RS13815	COG0596	Alpha beta hydrolase
ET471_RS13825	COG1937	Protein conserved in bacteria
ET471_RS13830	COG0446	pyridine nucleotide-disulphide oxidoreductase
ET471_RS13855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ET471_RS13855	COG2111	Na H antiporter
ET471_RS13860	COG1006	Multisubunit Na H antiporter MnhC subunit
ET471_RS13870	COG2076	Multidrug Resistance protein
ET471_RS13925	COG2223	nitrite transmembrane transporter activity
ET471_RS13930	COG0243	molybdopterin cofactor binding
ET471_RS13935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET471_RS13945	COG0315	cyclic pyranopterin monophosphate synthase activity
ET471_RS13960	COG2146	nitrite reductase [NAD(P)H] activity
ET471_RS13960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ET471_RS13995	COG1132	(ABC) transporter
ET471_RS14000	COG1132	(ABC) transporter
ET471_RS14010	COG3177	Filamentation induced by cAMP protein fic
ET471_RS14015	COG0583	DNA-binding transcription factor activity
ET471_RS14020	COG0009	L-threonylcarbamoyladenylate synthase
ET471_RS14030	COG1739	Uncharacterized protein family UPF0029
ET471_RS14040	COG0456	acetyltransferase
ET471_RS14055	COG0714	Associated with various cellular activities
ET471_RS14075	COG2378	regulation of single-species biofilm formation
ET471_RS14090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET471_RS14095	COG0805	protein transport
ET471_RS14100	COG1597	lipid kinase activity
ET471_RS14110	COG1228	amidohydrolase
ET471_RS14115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ET471_RS14125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS14165	COG1595	DNA-templated transcription, initiation
ET471_RS14190	COG0137	argininosuccinate synthase activity
ET471_RS14205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS14225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ET471_RS14240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ET471_RS14245	COG3340	Belongs to the peptidase S51 family
ET471_RS14285	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ET471_RS14305	COG1716	ATPase activity
ET471_RS14340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ET471_RS14345	COG0140	phosphoribosyl-ATP diphosphatase activity
ET471_RS14350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ET471_RS14355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET471_RS14355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ET471_RS14370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ET471_RS14385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ET471_RS14405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ET471_RS14415	COG1758	RNA polymerase activity
ET471_RS14420	COG0194	GDP metabolic process
ET471_RS14425	COG0322	excinuclease ABC activity
ET471_RS14435	COG0284	orotidine-5'-phosphate decarboxylase activity
ET471_RS14440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ET471_RS14455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ET471_RS14460	COG0540	Belongs to the ATCase OTCase family
ET471_RS14465	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ET471_RS14470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ET471_RS14475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ET471_RS14495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ET471_RS14525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ET471_RS14525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ET471_RS14530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ET471_RS14535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ET471_RS14540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ET471_RS14545	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ET471_RS14560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ET471_RS14565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ET471_RS14580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ET471_RS14605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ET471_RS14625	COG0124	histidyl-tRNA synthetase
ET471_RS14630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET471_RS14640	COG1196	nuclear chromosome segregation
ET471_RS14655	COG1793	dna ligase
ET471_RS14660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ET471_RS14665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ET471_RS14685	COG2255	four-way junction helicase activity
ET471_RS14690	COG0632	four-way junction helicase activity
ET471_RS14695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ET471_RS14700	COG0217	transcriptional regulatory protein
ET471_RS14705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ET471_RS14710	COG0494	nUDIX hydrolase
ET471_RS14715	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ET471_RS14725	COG0438	transferase activity, transferring glycosyl groups
ET471_RS14730	COG1560	Kdo2-lipid A biosynthetic process
ET471_RS14735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ET471_RS14745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ET471_RS14780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ET471_RS14785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ET471_RS14790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ET471_RS14830	COG0738	Major facilitator superfamily
ET471_RS14855	COG1595	DNA-templated transcription, initiation
ET471_RS14895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ET471_RS14900	COG0859	PFAM glycosyl transferase family 9
ET471_RS14910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ET471_RS14910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ET471_RS14915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ET471_RS14920	COG0438	transferase activity, transferring glycosyl groups
ET471_RS14935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ET471_RS14940	COG2192	nodulation
ET471_RS15000	COG2721	sulfolactate sulfo-lyase activity
ET471_RS15005	COG0492	ferredoxin-NADP+ reductase activity
ET471_RS15050	COG3548	integral membrane protein
ET471_RS15065	COG2814	Major facilitator Superfamily
ET471_RS15070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ET471_RS15080	COG0395	ABC-type sugar transport system, permease component
ET471_RS15085	COG4209	transmembrane transport
ET471_RS15095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ET471_RS15120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ET471_RS15220	COG2326	polyphosphate kinase activity
ET471_RS15255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ET471_RS15270	COG0183	Belongs to the thiolase family
ET471_RS15280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ET471_RS15290	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ET471_RS15305	COG3973	AAA domain
ET471_RS15315	COG0494	nUDIX hydrolase
ET471_RS15335	COG1131	(ABC) transporter
ET471_RS15340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ET471_RS15370	COG0531	amino acid
ET471_RS15375	COG0569	domain protein
ET471_RS15400	COG0756	dUTP diphosphatase activity
ET471_RS15420	COG2860	membrane
ET471_RS15430	COG1435	thymidine kinase activity
ET471_RS15455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ET471_RS15485	COG1410	methionine synthase
ET471_RS15485	COG0646	methionine synthase
ET471_RS15505	COG0477	Major facilitator Superfamily
ET471_RS15525	COG1846	Transcriptional regulator
ET471_RS15530	COG2814	Major facilitator Superfamily
ET471_RS15540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ET471_RS15540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ET471_RS15545	COG3433	isochorismatase activity
ET471_RS15545	COG1535	isochorismatase
ET471_RS15550	COG1021	2,3-dihydroxybenzoate-AMP ligase
ET471_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
ET471_RS15570	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET471_RS15605	COG2375	cellular response to nickel ion
ET471_RS15610	COG2382	esterase
ET471_RS15640	COG0318	PFAM AMP-dependent synthetase and ligase
ET471_RS15680	COG3655	Transcriptional regulator
ET471_RS15715	COG0187	DNA topoisomerase II activity
ET471_RS15730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ET471_RS15735	COG0589	response to stress
ET471_RS15750	COG0142	geranyltranstransferase activity
ET471_RS15760	COG2815	serine threonine protein kinase
ET471_RS15760	COG0515	serine threonine protein kinase
ET471_RS15765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ET471_RS15785	COG1940	carbohydrate kinase activity
ET471_RS15805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ET471_RS15815	COG1845	cytochrome c oxidase, subunit III
ET471_RS15825	COG0723	plastoquinol--plastocyanin reductase activity
ET471_RS15830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ET471_RS15845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ET471_RS15850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ET471_RS15885	COG0667	Aldo Keto reductase
ET471_RS15905	COG0167	dihydroorotate dehydrogenase activity
ET471_RS15920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ET471_RS15925	COG0508	dehydrogenase complex catalyzes the overall conversion of
ET471_RS15940	COG0673	inositol 2-dehydrogenase activity
ET471_RS15945	COG0321	lipoyl(octanoyl) transferase activity
ET471_RS15950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ET471_RS15985	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ET471_RS15990	COG0174	glutamine synthetase
ET471_RS16060	COG3022	response to hydroperoxide
ET471_RS16080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ET471_RS16090	COG0659	secondary active sulfate transmembrane transporter activity
ET471_RS16120	COG0514	ATP-dependent DNA helicase (RecQ)
ET471_RS16140	COG0633	Ferredoxin
ET471_RS16140	COG0543	2 iron, 2 sulfur cluster binding
ET471_RS16170	COG4605	iron ion homeostasis
ET471_RS16175	COG4604	ABC transporter, ATP-binding protein
ET471_RS16180	COG0183	Belongs to the thiolase family
ET471_RS16190	COG1250	3-hydroxyacyl-CoA dehydrogenase
ET471_RS16195	COG2050	protein possibly involved in aromatic compounds catabolism
ET471_RS16200	COG1012	belongs to the aldehyde dehydrogenase family
ET471_RS16200	COG2030	dehydratase
ET471_RS16215	COG2050	protein possibly involved in aromatic compounds catabolism
ET471_RS16220	COG3396	Phenylacetate-CoA oxygenase
ET471_RS16225	COG3460	Phenylacetate-CoA oxygenase
ET471_RS16235	COG2151	metal-sulfur cluster biosynthetic enzyme
ET471_RS16240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ET471_RS16255	COG1518	maintenance of DNA repeat elements
ET471_RS16270	COG1857	crispr-associated protein
ET471_RS16295	COG0577	efflux transmembrane transporter activity
ET471_RS16295	COG1136	(ABC) transporter
ET471_RS16300	COG2197	response regulator
ET471_RS16320	COG3973	AAA domain
ET471_RS16335	COG0577	efflux transmembrane transporter activity
ET471_RS16335	COG1136	(ABC) transporter
ET471_RS16395	COG2197	response regulator
ET471_RS16400	COG0515	serine threonine protein kinase
ET471_RS16420	COG1131	(ABC) transporter
ET471_RS16470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ET471_RS16475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ET471_RS16480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ET471_RS16550	COG0542	response to heat
ET471_RS16570	COG2814	Major facilitator Superfamily
ET471_RS16580	COG3639	organic phosphonate transmembrane transporter activity
ET471_RS16585	COG3639	organic phosphonate transmembrane transporter activity
ET471_RS16590	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ET471_RS16615	COG0366	Alpha amylase catalytic
ET471_RS16630	COG1175	transmembrane transport
ET471_RS16635	COG2182	Extracellular solute-binding protein
ET471_RS16645	COG0366	Alpha amylase catalytic
ET471_RS16660	COG2197	response regulator
ET471_RS16685	COG1695	Transcriptional regulator
ET471_RS16695	COG0423	glycine-tRNA ligase activity
ET471_RS16700	COG3443	Belongs to the bacterial solute-binding protein 9 family
ET471_RS16700	COG0803	Belongs to the bacterial solute-binding protein 9 family
ET471_RS16705	COG1121	(ABC) transporter
ET471_RS16710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ET471_RS16720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET471_RS16725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ET471_RS16730	COG1120	ATPase activity
ET471_RS16740	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ET471_RS16745	COG1381	Involved in DNA repair and RecF pathway recombination
ET471_RS16750	COG0740	serine-type endopeptidase activity
ET471_RS16755	COG0740	serine-type endopeptidase activity
ET471_RS16760	COG1396	sequence-specific DNA binding
ET471_RS16765	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ET471_RS16780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ET471_RS16790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ET471_RS16800	COG0537	adenosine 5'-monophosphoramidase activity
ET471_RS16810	COG0484	heat shock protein binding
ET471_RS16815	COG1420	regulation of RNA biosynthetic process
ET471_RS16840	COG2365	Tyrosine phosphatase family
ET471_RS16850	COG0481	GTPase activity
ET471_RS16860	COG1136	(ABC) transporter
ET471_RS16885	COG1305	Transglutaminase-like
ET471_RS16905	COG0268	Binds directly to 16S ribosomal RNA
ET471_RS16915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ET471_RS16935	COG1053	succinate dehydrogenase
ET471_RS16945	COG1307	EDD domain protein, DegV family
ET471_RS16950	COG0433	COG0433 Predicted ATPase
ET471_RS16955	COG0254	rRNA binding
ET471_RS16970	COG0058	SHG alpha-glucan phosphorylase activity
ET471_RS17000	COG4221	oxidoreductase activity
ET471_RS17025	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ET471_RS17030	COG2357	RelA SpoT domain protein
ET471_RS17070	COG0579	oxidoreductase
ET471_RS17090	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ET471_RS17095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ET471_RS17105	COG0667	Aldo Keto reductase
ET471_RS17110	COG1309	transcriptional regulator
ET471_RS17130	COG0799	negative regulation of ribosome biogenesis
ET471_RS17140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ET471_RS17145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ET471_RS17150	COG0477	Major facilitator Superfamily
ET471_RS17155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ET471_RS17165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ET471_RS17170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ET471_RS17175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ET471_RS17180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ET471_RS17190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ET471_RS17195	COG1435	thymidine kinase activity
ET471_RS17200	COG1530	ribonuclease E activity
ET471_RS17205	COG1271	oxidase subunit
ET471_RS17210	COG1294	oxidase, subunit
ET471_RS17215	COG4988	ABC transporter
ET471_RS17220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ET471_RS17230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ET471_RS17235	COG0571	ribonuclease III activity
ET471_RS17240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ET471_RS17260	COG0742	ribosomal rna small subunit methyltransferase
ET471_RS17265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ET471_RS17275	COG1461	Dihydroxyacetone kinase
ET471_RS17280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ET471_RS17310	COG1181	Belongs to the D-alanine--D-alanine ligase family
ET471_RS17320	COG0009	L-threonylcarbamoyladenylate synthase
ET471_RS17325	COG2271	Major facilitator Superfamily
ET471_RS17330	COG4977	sequence-specific DNA binding
ET471_RS17345	COG1136	(ABC) transporter
ET471_RS17345	COG4591	ABC-type transport system involved in lipoprotein release permease component
ET471_RS17355	COG3173	Aminoglycoside phosphotransferase
ET471_RS17360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ET471_RS17370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ET471_RS17375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ET471_RS17385	COG0477	Major facilitator Superfamily
ET471_RS17390	COG0110	maltose O-acetyltransferase activity
ET471_RS17400	COG0602	queuosine metabolic process
ET471_RS17405	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ET471_RS17405	COG1328	CTP reductase activity
ET471_RS17430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ET471_RS17435	COG0747	negative chemotaxis
ET471_RS17445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ET471_RS17460	COG0277	FAD linked oxidase domain protein
ET471_RS17465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ET471_RS17525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET471_RS17530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ET471_RS17600	COG4962	Type ii secretion system protein e
ET471_RS17645	COG3547	Transposase (IS116 IS110 IS902 family)
ET471_RS17655	COG0534	Mate efflux family protein
ET471_RS17665	COG2149	membrane
ET471_RS17675	COG0154	amidase activity
ET471_RS17690	COG0154	amidase activity
ET471_RS17705	COG3684	Belongs to the aldolase LacD family
ET471_RS17725	COG1175	transmembrane transport
ET471_RS17730	COG0395	ABC-type sugar transport system, permease component
ET471_RS17740	COG2723	6-phospho-beta-galactosidase activity
ET471_RS17755	COG1609	Transcriptional regulator
ET471_RS17790	COG3119	arylsulfatase activity
ET471_RS17795	COG0235	Class ii aldolase
ET471_RS17800	COG3395	kinase activity