locus-tag	class	description
XFASM12_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XFASM12_RS00030	COG0187	DNA topoisomerase II activity
XFASM12_RS00040	COG0501	Belongs to the peptidase M48B family
XFASM12_RS00095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XFASM12_RS00165	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XFASM12_RS00175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XFASM12_RS00190	COG0511	ligase activity, forming carbon-carbon bonds
XFASM12_RS00195	COG0439	Biotin carboxylase
XFASM12_RS00200	COG0210	DNA helicase
XFASM12_RS00230	COG1040	competence protein
XFASM12_RS00240	COG1752	Esterase of the alpha-beta hydrolase superfamily
XFASM12_RS00280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFASM12_RS00290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XFASM12_RS00320	COG3121	Chaperone
XFASM12_RS00325	COG3539	Fimbrial protein
XFASM12_RS00330	COG1546	Belongs to the CinA family
XFASM12_RS00335	COG0477	Major facilitator Superfamily
XFASM12_RS00340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XFASM12_RS00355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XFASM12_RS00365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XFASM12_RS00375	COG1534	Rna-binding protein
XFASM12_RS00405	COG1560	Kdo2-lipid A biosynthetic process
XFASM12_RS00410	COG1519	Transferase
XFASM12_RS00430	COG0336	Belongs to the RNA methyltransferase TrmD family
XFASM12_RS00450	COG1393	Belongs to the ArsC family
XFASM12_RS00460	COG0367	asparagine synthase
XFASM12_RS00470	COG2070	2-Nitropropane dioxygenase
XFASM12_RS00500	COG0339	signal peptide processing
XFASM12_RS00585	COG4221	oxidoreductase activity
XFASM12_RS00605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XFASM12_RS00615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFASM12_RS00660	COG2223	nitrite transmembrane transporter activity
XFASM12_RS00670	COG0739	heme binding
XFASM12_RS00705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFASM12_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM12_RS00730	COG1272	protein, Hemolysin III
XFASM12_RS00735	COG0463	Glycosyl transferase, family 2
XFASM12_RS00740	COG0084	hydrolase, TatD family'
XFASM12_RS00770	COG0330	HflC and HflK could
XFASM12_RS00775	COG3956	TIGRFAM MazG family protein
XFASM12_RS00785	COG0494	nUDIX hydrolase
XFASM12_RS00795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XFASM12_RS00800	COG0513	Belongs to the DEAD box helicase family
XFASM12_RS00805	COG0720	synthase
XFASM12_RS00830	COG1981	membrane
XFASM12_RS00865	COG0512	Glutamine amidotransferase of anthranilate synthase
XFASM12_RS00900	COG0006	proline dipeptidase activity
XFASM12_RS00925	COG1862	Preprotein translocase
XFASM12_RS00930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFASM12_RS00935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFASM12_RS00945	COG0617	tRNA 3'-terminal CCA addition
XFASM12_RS00990	COG0195	Participates in both transcription termination and antitermination
XFASM12_RS01020	COG1733	regulation of RNA biosynthetic process
XFASM12_RS01025	COG0702	epimerase
XFASM12_RS01075	COG2086	electron transfer activity
XFASM12_RS01105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFASM12_RS01130	COG0477	Major facilitator Superfamily
XFASM12_RS01150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XFASM12_RS01155	COG0671	phosphoesterase, PA-phosphatase related
XFASM12_RS01165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XFASM12_RS01170	COG0628	permease
XFASM12_RS01190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFASM12_RS01195	COG1090	epimerase
XFASM12_RS01200	COG0318	PFAM AMP-dependent synthetase and ligase
XFASM12_RS01220	COG1049	propionate catabolic process, 2-methylcitrate cycle
XFASM12_RS01240	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFASM12_RS01245	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFASM12_RS01285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFASM12_RS01310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFASM12_RS01330	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XFASM12_RS01335	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XFASM12_RS01340	COG1034	ATP synthesis coupled electron transport
XFASM12_RS01375	COG1007	ATP synthesis coupled electron transport
XFASM12_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM12_RS01385	COG2851	Citrate transporter
XFASM12_RS01400	COG0642	Histidine kinase
XFASM12_RS01415	COG2205	protein histidine kinase activity
XFASM12_RS01415	COG0784	Response regulator, receiver
XFASM12_RS01435	COG0281	malic enzyme
XFASM12_RS01435	COG0280	phosphate acetyltransferase
XFASM12_RS01445	COG0742	ribosomal rna small subunit methyltransferase
XFASM12_RS01460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XFASM12_RS01480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XFASM12_RS01505	COG2166	iron-sulfur cluster assembly
XFASM12_RS01535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XFASM12_RS01605	COG1914	H( )-stimulated, divalent metal cation uptake system
XFASM12_RS01620	COG1946	Acyl-CoA thioesterase
XFASM12_RS01700	COG0750	zinc metalloprotease
XFASM12_RS01710	COG0575	Belongs to the CDS family
XFASM12_RS01715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
XFASM12_RS01745	COG0528	UMP kinase activity
XFASM12_RS01790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XFASM12_RS01800	COG0354	folic acid binding
XFASM12_RS01810	COG2009	succinate dehydrogenase
XFASM12_RS01815	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XFASM12_RS01825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XFASM12_RS01855	COG0811	peptide transport
XFASM12_RS01945	COG3093	addiction module antidote protein HigA
XFASM12_RS02015	COG3772	lysozyme
XFASM12_RS02085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFASM12_RS02115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XFASM12_RS02115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XFASM12_RS02145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XFASM12_RS02150	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XFASM12_RS02170	COG1024	Enoyl-CoA hydratase
XFASM12_RS02175	COG0527	aspartate kinase activity
XFASM12_RS02195	COG0494	nUDIX hydrolase
XFASM12_RS02200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XFASM12_RS02210	COG0424	maF-like protein
XFASM12_RS02225	COG0312	modulator of DNA gyrase
XFASM12_RS02235	COG0312	modulator of DNA gyrase
XFASM12_RS02240	COG0583	DNA-binding transcription factor activity
XFASM12_RS02255	COG1064	alcohol dehydrogenase
XFASM12_RS02310	COG0356	it plays a direct role in the translocation of protons across the membrane
XFASM12_RS02360	COG0255	Belongs to the universal ribosomal protein uL29 family
XFASM12_RS02410	COG0201	protein transport
XFASM12_RS02440	COG2960	long-chain fatty acid transporting porin activity
XFASM12_RS02445	COG0606	chelatase, subunit chli
XFASM12_RS02465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XFASM12_RS02530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFASM12_RS02535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFASM12_RS02550	COG1187	pseudouridine synthase activity
XFASM12_RS02555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XFASM12_RS02575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFASM12_RS02590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XFASM12_RS02595	COG1217	gtp-binding protein TYPA
XFASM12_RS02620	COG0842	Transport permease protein
XFASM12_RS02625	COG1131	(ABC) transporter
XFASM12_RS02645	COG1643	Atp-dependent helicase
XFASM12_RS02655	COG1956	GAF domain-containing protein
XFASM12_RS02660	COG0729	surface antigen
XFASM12_RS02665	COG2911	Protein conserved in bacteria
XFASM12_RS02745	COG0668	transmembrane transport
XFASM12_RS02775	COG5297	Belongs to the glycosyl hydrolase family 6
XFASM12_RS02810	COG2733	membrane
XFASM12_RS02815	COG1253	flavin adenine dinucleotide binding
XFASM12_RS02865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XFASM12_RS02880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XFASM12_RS02880	COG0644	oxidoreductase
XFASM12_RS02895	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XFASM12_RS02895	COG3218	ABC-type transport auxiliary lipoprotein component
XFASM12_RS02900	COG1127	ABC transporter
XFASM12_RS02905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFASM12_RS02925	COG0629	single-stranded DNA binding
XFASM12_RS02945	COG4969	Belongs to the N-Me-Phe pilin family
XFASM12_RS03055	COG0675	Transposase, IS605 OrfB family
XFASM12_RS03110	COG1077	Cell shape determining protein MreB Mrl
XFASM12_RS03115	COG1792	Involved in formation and maintenance of cell shape
XFASM12_RS03120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XFASM12_RS03125	COG0768	penicillin binding
XFASM12_RS03130	COG0772	Belongs to the SEDS family
XFASM12_RS03140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFASM12_RS03160	COG2894	cell division
XFASM12_RS03185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XFASM12_RS03200	COG2353	YceI-like domain
XFASM12_RS03205	COG2198	Histidine kinase
XFASM12_RS03205	COG0784	Response regulator, receiver
XFASM12_RS03205	COG2205	protein histidine kinase activity
XFASM12_RS03250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XFASM12_RS03255	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XFASM12_RS03260	COG4208	sulfate ABC transporter
XFASM12_RS03285	COG1846	Transcriptional regulator
XFASM12_RS03315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XFASM12_RS03325	COG0741	lytic transglycosylase activity
XFASM12_RS03350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XFASM12_RS03385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XFASM12_RS03395	COG0514	ATP-dependent DNA helicase (RecQ)
XFASM12_RS03400	COG0783	Belongs to the Dps family
XFASM12_RS03405	COG1643	Atp-dependent helicase
XFASM12_RS03415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XFASM12_RS03420	COG1845	cytochrome c oxidase, subunit III
XFASM12_RS03425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XFASM12_RS03430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XFASM12_RS03435	COG0142	geranyltranstransferase activity
XFASM12_RS03440	COG0629	single-stranded DNA binding
XFASM12_RS03475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XFASM12_RS03510	COG1137	ATPase activity
XFASM12_RS03525	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XFASM12_RS03535	COG0271	Belongs to the BolA IbaG family
XFASM12_RS03575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFASM12_RS03585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XFASM12_RS03600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XFASM12_RS03620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFASM12_RS03650	COG0542	response to heat
XFASM12_RS03670	COG0492	ferredoxin-NADP+ reductase activity
XFASM12_RS03690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XFASM12_RS03705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XFASM12_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM12_RS03740	COG1609	Transcriptional regulator
XFASM12_RS03745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XFASM12_RS03750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XFASM12_RS03755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XFASM12_RS03760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFASM12_RS03765	COG0726	polysaccharide deacetylase
XFASM12_RS03770	COG0297	glycogen (starch) synthase activity
XFASM12_RS03790	COG0719	Fe-S assembly protein
XFASM12_RS03795	COG0396	ATPase activity
XFASM12_RS03800	COG0719	Fe-S assembly protein
XFASM12_RS03805	COG1959	2 iron, 2 sulfur cluster binding
XFASM12_RS03855	COG0308	aminopeptidase N
XFASM12_RS03900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XFASM12_RS03925	COG1561	YicC-like family, N-terminal region
XFASM12_RS03940	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XFASM12_RS03980	COG5295	Hep Hag repeat protein
XFASM12_RS03985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XFASM12_RS03990	COG1459	type II secretion system
XFASM12_RS03995	COG2165	general secretion pathway protein
XFASM12_RS04000	COG4970	Tfp pilus assembly protein FimT
XFASM12_RS04005	COG2165	general secretion pathway protein
XFASM12_RS04010	COG4795	General secretion pathway protein
XFASM12_RS04015	COG3156	type II secretion system protein K
XFASM12_RS04020	COG3166	PFAM Fimbrial assembly family protein
XFASM12_RS04035	COG1450	Type ii and iii secretion system protein
XFASM12_RS04050	COG3634	alkyl hydroperoxide reductase activity
XFASM12_RS04055	COG0583	DNA-binding transcription factor activity
XFASM12_RS04115	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XFASM12_RS04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
XFASM12_RS04140	COG0567	Dehydrogenase, E1 component
XFASM12_RS04145	COG2850	peptidyl-arginine hydroxylation
XFASM12_RS04265	COG3772	lysozyme
XFASM12_RS04340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFASM12_RS04345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFASM12_RS04355	COG2902	Dehydrogenase
XFASM12_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM12_RS04425	COG1472	Belongs to the glycosyl hydrolase 3 family
XFASM12_RS04445	COG2925	Exonuclease
XFASM12_RS04460	COG0025	NhaP-type Na H and K H
XFASM12_RS04480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XFASM12_RS04500	COG0006	proline dipeptidase activity
XFASM12_RS04510	COG0778	Nitroreductase
XFASM12_RS04545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XFASM12_RS04580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XFASM12_RS04595	COG0557	exoribonuclease II activity
XFASM12_RS04605	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XFASM12_RS04620	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XFASM12_RS04625	COG1289	transmembrane transporter activity
XFASM12_RS04650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XFASM12_RS04660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFASM12_RS04675	COG0596	Alpha beta hydrolase
XFASM12_RS04680	COG0727	PFAM Uncharacterised protein family (UPF0153)
XFASM12_RS04685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XFASM12_RS04685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XFASM12_RS04725	COG0840	transmembrane signaling receptor activity
XFASM12_RS04730	COG2198	Histidine kinase
XFASM12_RS04730	COG0643	Histidine kinase
XFASM12_RS04730	COG0784	Response regulator, receiver
XFASM12_RS04760	COG0285	dihydrofolate synthase activity
XFASM12_RS04770	COG0339	signal peptide processing
XFASM12_RS04795	COG1301	dicarboxylic acid transport
XFASM12_RS04800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XFASM12_RS04810	COG2091	lysine biosynthetic process via aminoadipic acid
XFASM12_RS04865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XFASM12_RS04895	COG0084	hydrolase, TatD family'
XFASM12_RS04910	COG0552	protein localization to endoplasmic reticulum
XFASM12_RS04950	COG0824	Thioesterase
XFASM12_RS04975	COG2885	chlorophyll binding
XFASM12_RS04985	COG0602	queuosine metabolic process
XFASM12_RS05005	COG0386	Belongs to the glutathione peroxidase family
XFASM12_RS05025	COG0406	alpha-ribazole phosphatase activity
XFASM12_RS05195	COG3852	Histidine kinase
XFASM12_RS05200	COG2204	response regulator
XFASM12_RS05210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XFASM12_RS05215	COG0004	ammonium transporteR
XFASM12_RS05220	COG0347	Belongs to the P(II) protein family
XFASM12_RS05225	COG0174	glutamine synthetase
XFASM12_RS05230	COG1968	undecaprenyl-diphosphatase activity
XFASM12_RS05235	COG2353	YceI-like domain
XFASM12_RS05320	COG3093	addiction module antidote protein HigA
XFASM12_RS05390	COG3772	lysozyme
XFASM12_RS05520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFASM12_RS05570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XFASM12_RS05575	COG1764	response to oxidative stress
XFASM12_RS05580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFASM12_RS05590	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XFASM12_RS05615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFASM12_RS05625	COG1399	metal-binding, possibly nucleic acid-binding protein
XFASM12_RS05635	COG0714	Associated with various cellular activities
XFASM12_RS05655	COG0537	adenosine 5'-monophosphoramidase activity
XFASM12_RS05740	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
XFASM12_RS05765	COG4969	Belongs to the N-Me-Phe pilin family
XFASM12_RS05780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XFASM12_RS05785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XFASM12_RS05795	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XFASM12_RS05810	COG0251	oxidation-reduction process
XFASM12_RS05815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XFASM12_RS05815	COG0392	lysyltransferase activity
XFASM12_RS05830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XFASM12_RS05840	COG0463	Glycosyl transferase, family 2
XFASM12_RS05890	COG3275	phosphorelay sensor kinase activity
XFASM12_RS05895	COG0400	carboxylic ester hydrolase activity
XFASM12_RS05920	COG2226	methyltransferase
XFASM12_RS05930	COG2027	D-alanyl-D-alanine carboxypeptidase
XFASM12_RS05945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFASM12_RS05975	COG0386	Belongs to the glutathione peroxidase family
XFASM12_RS05985	COG1131	(ABC) transporter
XFASM12_RS06110	COG2369	cell adhesion
XFASM12_RS06120	COG5410	chromosome segregation
XFASM12_RS06145	COG3772	lysozyme
XFASM12_RS06215	COG0489	protein tyrosine kinase activity
XFASM12_RS06225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XFASM12_RS06285	COG0488	(ABC) transporter
XFASM12_RS06305	COG4651	solute:proton antiporter activity
XFASM12_RS06305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XFASM12_RS06365	COG0859	PFAM glycosyl transferase family 9
XFASM12_RS06380	COG0631	protein serine/threonine phosphatase activity
XFASM12_RS06385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XFASM12_RS06390	COG0328	RNA-DNA hybrid ribonuclease activity
XFASM12_RS06405	COG2183	response to ionizing radiation
XFASM12_RS06420	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XFASM12_RS06425	COG3118	belongs to the thioredoxin family
XFASM12_RS06470	COG2951	lytic endotransglycosylase activity
XFASM12_RS06475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XFASM12_RS06615	COG0277	FAD linked oxidase domain protein
XFASM12_RS06620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XFASM12_RS06630	COG0531	amino acid
XFASM12_RS06635	COG0531	amino acid
XFASM12_RS06715	COG0460	homoserine dehydrogenase
XFASM12_RS06715	COG0527	aspartate kinase activity
XFASM12_RS06720	COG0540	Belongs to the ATCase OTCase family
XFASM12_RS06735	COG1686	Belongs to the peptidase S11 family
XFASM12_RS06760	COG4953	penicillin-binding protein 1C
XFASM12_RS06780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFASM12_RS06850	COG0823	Involved in the tonB-independent uptake of proteins
XFASM12_RS06850	COG1506	peptidase
XFASM12_RS06855	COG1297	OPT oligopeptide transporter protein
XFASM12_RS06885	COG0676	glucose-6-phosphate 1-epimerase activity
XFASM12_RS06895	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XFASM12_RS06900	COG1335	isochorismatase
XFASM12_RS06905	COG0318	PFAM AMP-dependent synthetase and ligase
XFASM12_RS06915	COG0463	Glycosyl transferase, family 2
XFASM12_RS06930	COG1192	Involved in chromosome partitioning
XFASM12_RS06985	COG3772	lysozyme
XFASM12_RS07020	COG1605	Chorismate mutase
XFASM12_RS07020	COG0077	Prephenate dehydratase
XFASM12_RS07035	COG1668	transmembrane transport
XFASM12_RS07040	COG4555	ABC transporter
XFASM12_RS07065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XFASM12_RS07075	COG0287	Prephenate dehydrogenase
XFASM12_RS07075	COG1605	Chorismate mutase
XFASM12_RS07100	COG0497	DNA recombination
XFASM12_RS07110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFASM12_RS07115	COG2914	Belongs to the UPF0125 (RnfH) family
XFASM12_RS07145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XFASM12_RS07155	COG2954	triphosphatase activity
XFASM12_RS07165	COG0745	RESPONSE REGULATOR receiver
XFASM12_RS07170	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XFASM12_RS07175	COG0438	transferase activity, transferring glycosyl groups
XFASM12_RS07190	COG0438	transferase activity, transferring glycosyl groups
XFASM12_RS07245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFASM12_RS07250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFASM12_RS07255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFASM12_RS07265	COG1064	alcohol dehydrogenase
XFASM12_RS07285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFASM12_RS07315	COG3609	addiction module antidote protein, CC2985 family
XFASM12_RS07325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
XFASM12_RS07330	COG0675	Transposase, IS605 OrfB family
XFASM12_RS07340	COG0436	Aminotransferase
XFASM12_RS07415	COG0196	riboflavin kinase activity
XFASM12_RS07420	COG0728	peptidoglycan biosynthetic process
XFASM12_RS07425	COG0268	Binds directly to 16S ribosomal RNA
XFASM12_RS07445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XFASM12_RS07465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XFASM12_RS07470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XFASM12_RS07485	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XFASM12_RS07495	COG0776	regulation of translation
XFASM12_RS07535	COG0395	ABC-type sugar transport system, permease component
XFASM12_RS07540	COG1175	transmembrane transport
XFASM12_RS07570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XFASM12_RS07590	COG0436	Aminotransferase
XFASM12_RS07595	COG4133	protoheme IX ABC transporter activity
XFASM12_RS07610	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XFASM12_RS07620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XFASM12_RS07645	COG5434	Belongs to the glycosyl hydrolase 28 family
XFASM12_RS07665	COG0402	S-adenosylhomocysteine deaminase activity
XFASM12_RS07675	COG1509	lysine 2,3-aminomutase activity
XFASM12_RS07710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XFASM12_RS07715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XFASM12_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM12_RS07760	COG0142	geranyltranstransferase activity
XFASM12_RS07770	COG0037	tRNA processing
XFASM12_RS07780	COG1301	dicarboxylic acid transport
XFASM12_RS07790	COG0791	NLP P60 protein
XFASM12_RS07795	COG0791	NLP P60 protein
XFASM12_RS07805	COG2311	Membrane
XFASM12_RS07820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XFASM12_RS07935	COG0351	phosphomethylpyrimidine kinase
XFASM12_RS07935	COG0352	thiamine-phosphate diphosphorylase activity
XFASM12_RS07945	COG1324	tolerance protein
XFASM12_RS07985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFASM12_RS07990	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XFASM12_RS08005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XFASM12_RS08025	COG4774	siderophore transport
XFASM12_RS08050	COG1477	protein flavinylation
XFASM12_RS08055	COG1555	photosystem II stabilization
XFASM12_RS08060	COG3178	'Phosphotransferase
XFASM12_RS08065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XFASM12_RS08075	COG0628	permease
XFASM12_RS08085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XFASM12_RS08090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XFASM12_RS08110	COG3590	peptidase
XFASM12_RS08175	COG0519	Catalyzes the synthesis of GMP from XMP
XFASM12_RS08175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XFASM12_RS08185	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XFASM12_RS08205	COG3107	peptidoglycan biosynthetic process
XFASM12_RS08225	COG2878	Part of a membrane complex involved in electron transport
XFASM12_RS08265	COG0338	D12 class N6 adenine-specific DNA methyltransferase
XFASM12_RS08320	COG1611	Belongs to the LOG family
XFASM12_RS08325	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XFASM12_RS08330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XFASM12_RS08340	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFASM12_RS08370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XFASM12_RS08385	COG0330	HflC and HflK could
XFASM12_RS08390	COG0330	HflC and HflK could
XFASM12_RS08395	COG0604	alcohol dehydrogenase
XFASM12_RS08425	COG1183	phosphatidylcholine synthase activity
XFASM12_RS08445	COG0668	transmembrane transport
XFASM12_RS08450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XFASM12_RS08465	COG1610	YqeY-like protein
XFASM12_RS08475	COG0358	DNA primase activity
XFASM12_RS08505	COG1074	ATP-dependent DNA helicase activity
XFASM12_RS08510	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XFASM12_RS08515	COG1127	ABC transporter
XFASM12_RS08520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFASM12_RS08540	COG2853	Lipoprotein
XFASM12_RS08545	COG1322	Protein conserved in bacteria
XFASM12_RS08550	COG1116	anion transmembrane transporter activity
XFASM12_RS08560	COG0531	amino acid
XFASM12_RS08565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XFASM12_RS08570	COG0861	Integral membrane protein TerC family
XFASM12_RS08600	COG2193	ferroxidase activity
XFASM12_RS08645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XFASM12_RS08665	COG0542	response to heat
XFASM12_RS08675	COG0352	thiamine-phosphate diphosphorylase activity
XFASM12_RS08680	COG2124	cytochrome p450
XFASM12_RS08685	COG2194	sulfuric ester hydrolase activity
XFASM12_RS08725	COG0667	Aldo Keto reductase
XFASM12_RS08730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFASM12_RS08740	COG0305	Participates in initiation and elongation during chromosome replication
XFASM12_RS08755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XFASM12_RS08765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFASM12_RS08770	COG0277	FAD linked oxidase domain protein
XFASM12_RS08790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XFASM12_RS08795	COG4206	TonB-dependent receptor
XFASM12_RS08830	COG0675	Transposase, IS605 OrfB family
XFASM12_RS08880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XFASM12_RS08885	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XFASM12_RS08890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XFASM12_RS08905	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XFASM12_RS08930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFASM12_RS08930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFASM12_RS08950	COG0488	(ABC) transporter
XFASM12_RS08960	COG3011	Protein conserved in bacteria
XFASM12_RS08995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XFASM12_RS09020	COG0758	DNA mediated transformation
XFASM12_RS09065	COG2969	positive regulation of protein catabolic process
XFASM12_RS09070	COG0625	glutathione transferase activity
XFASM12_RS09075	COG2857	Cytochrome c1
XFASM12_RS09080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XFASM12_RS09085	COG0723	plastoquinol--plastocyanin reductase activity
XFASM12_RS09090	COG0741	lytic transglycosylase activity
XFASM12_RS09100	COG1702	phosphate starvation-inducible protein PhoH
XFASM12_RS09115	COG4535	Mg2 and Co2 transporter CorC
XFASM12_RS09125	COG0598	Magnesium transport protein CorA
XFASM12_RS09250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XFASM12_RS09260	COG1199	ATP-dependent helicase activity
XFASM12_RS09270	COG0288	reversible hydration of carbon dioxide
XFASM12_RS09290	COG2011	ABC-type metal ion transport system permease component
XFASM12_RS09295	COG1464	Belongs to the NlpA lipoprotein family
XFASM12_RS09305	COG0508	dehydrogenase complex catalyzes the overall conversion of
XFASM12_RS09310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XFASM12_RS09320	COG0626	cystathionine gamma-synthase activity
XFASM12_RS09325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFASM12_RS09330	COG0739	heme binding
XFASM12_RS09350	COG1238	metal cluster binding
XFASM12_RS09365	COG5002	protein histidine kinase activity
XFASM12_RS09390	COG1388	LysM domain
XFASM12_RS09390	COG3858	chitin binding
XFASM12_RS09395	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XFASM12_RS09405	COG1472	Belongs to the glycosyl hydrolase 3 family
XFASM12_RS09420	COG3537	Alpha-1,2-mannosidase
XFASM12_RS09445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFASM12_RS09450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFASM12_RS09500	COG0469	pyruvate kinase activity
XFASM12_RS09515	COG0735	belongs to the Fur family
XFASM12_RS09535	COG0612	Peptidase, M16
XFASM12_RS09550	COG4305	rare lipoprotein A
XFASM12_RS09560	COG0739	heme binding
XFASM12_RS09570	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
XFASM12_RS09585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XFASM12_RS09615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XFASM12_RS09630	COG3116	cell division
XFASM12_RS09650	COG0471	metal ion transport
XFASM12_RS09650	COG3273	potassium ion transport
XFASM12_RS09700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XFASM12_RS09745	COG0730	response to heat
XFASM12_RS09765	COG0860	N-Acetylmuramoyl-L-alanine amidase
XFASM12_RS09770	COG0802	atpase or kinase
XFASM12_RS09775	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XFASM12_RS09775	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XFASM12_RS09780	COG1570	exodeoxyribonuclease VII activity
XFASM12_RS09860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XFASM12_RS09885	COG0745	RESPONSE REGULATOR receiver
XFASM12_RS09890	COG0642	Histidine kinase
XFASM12_RS09900	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XFASM12_RS09940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XFASM12_RS09950	COG2831	hemolysin activation secretion protein
XFASM12_RS09980	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XFASM12_RS10025	COG0316	Belongs to the HesB IscA family
XFASM12_RS10065	COG0697	spore germination
XFASM12_RS10070	COG0671	phosphoesterase, PA-phosphatase related
XFASM12_RS10075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XFASM12_RS10085	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XFASM12_RS10090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XFASM12_RS10105	COG1132	(ABC) transporter
XFASM12_RS10115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XFASM12_RS10120	COG1538	Outer membrane efflux protein
XFASM12_RS10145	COG0745	RESPONSE REGULATOR receiver
XFASM12_RS10150	COG4783	chaperone-mediated protein folding
XFASM12_RS10160	COG0473	3-isopropylmalate dehydrogenase activity
XFASM12_RS10170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XFASM12_RS10175	COG3083	sulfuric ester hydrolase activity
XFASM12_RS10180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XFASM12_RS10205	COG0564	pseudouridine synthase activity
XFASM12_RS10210	COG1530	ribonuclease E activity
XFASM12_RS10215	COG2197	response regulator
XFASM12_RS10230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XFASM12_RS10245	COG0488	(ABC) transporter
XFASM12_RS10260	COG1278	Cold shock
XFASM12_RS10265	COG3706	GGDEF domain
XFASM12_RS10265	COG4251	negative regulation of phosphorylation
XFASM12_RS10265	COG5001	Diguanylate cyclase
XFASM12_RS10265	COG2203	Gaf domain
XFASM12_RS10275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XFASM12_RS10320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XFASM12_RS10325	COG0250	Participates in transcription elongation, termination and antitermination
XFASM12_RS10330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XFASM12_RS10340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XFASM12_RS10360	COG0012	GTP binding
XFASM12_RS10375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XFASM12_RS10440	COG2095	MarC family integral membrane protein
XFASM12_RS10445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFASM12_RS10475	COG2132	Multicopper oxidase
XFASM12_RS10485	COG0210	DNA helicase
XFASM12_RS10495	COG0616	signal peptide processing
XFASM12_RS10520	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XFASM12_RS10535	COG2201	protein-glutamate methylesterase activity
XFASM12_RS10540	COG2177	Part of the ABC transporter FtsEX involved in
XFASM12_RS10545	COG2884	Cell division ATP-binding protein ftsE
XFASM12_RS10550	COG0513	Belongs to the DEAD box helicase family
XFASM12_RS10555	COG3118	belongs to the thioredoxin family
XFASM12_RS10560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XFASM12_RS10575	COG0793	Belongs to the peptidase S41A family
XFASM12_RS10580	COG4942	peptidase
XFASM12_RS10595	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFASM12_RS10600	COG0493	'glutamate synthase
XFASM12_RS10605	COG0067	glutamate synthase
XFASM12_RS10605	COG0070	glutamate synthase
XFASM12_RS10605	COG0069	glutamate synthase activity
XFASM12_RS10640	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFASM12_RS10680	COG1280	lysine exporter protein (LysE YggA)
XFASM12_RS10695	COG4942	peptidase
XFASM12_RS10715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFASM12_RS10825	COG1487	ribonuclease activity
XFASM12_RS10830	COG4691	Plasmid stability protein
XFASM12_RS10960	COG0594	ribonuclease P activity