locus-tag	class	description
XFASM23_RS00010	COG0592	DNA-directed DNA polymerase activity
XFASM23_RS00025	COG0187	DNA topoisomerase II activity
XFASM23_RS00035	COG0501	Belongs to the peptidase M48B family
XFASM23_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
XFASM23_RS00065	COG1506	peptidase
XFASM23_RS00065	COG4946	Tricorn protease homolog
XFASM23_RS00095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XFASM23_RS00175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XFASM23_RS00185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XFASM23_RS00200	COG0511	ligase activity, forming carbon-carbon bonds
XFASM23_RS00205	COG0439	Biotin carboxylase
XFASM23_RS00210	COG0210	DNA helicase
XFASM23_RS00240	COG1040	competence protein
XFASM23_RS00250	COG1752	Esterase of the alpha-beta hydrolase superfamily
XFASM23_RS00295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFASM23_RS00305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XFASM23_RS00340	COG3121	Chaperone
XFASM23_RS00345	COG3539	Fimbrial protein
XFASM23_RS00350	COG1546	Belongs to the CinA family
XFASM23_RS00355	COG0477	Major facilitator Superfamily
XFASM23_RS00360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XFASM23_RS00375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XFASM23_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
XFASM23_RS00395	COG1534	Rna-binding protein
XFASM23_RS00425	COG1560	Kdo2-lipid A biosynthetic process
XFASM23_RS00430	COG1519	Transferase
XFASM23_RS00470	COG1393	Belongs to the ArsC family
XFASM23_RS00480	COG0367	asparagine synthase
XFASM23_RS00490	COG2070	2-Nitropropane dioxygenase
XFASM23_RS00520	COG0339	signal peptide processing
XFASM23_RS00535	COG2132	Multicopper oxidase
XFASM23_RS00570	COG0795	lipopolysaccharide-transporting ATPase activity
XFASM23_RS00605	COG4221	oxidoreductase activity
XFASM23_RS00625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XFASM23_RS00695	COG2223	nitrite transmembrane transporter activity
XFASM23_RS00705	COG0739	heme binding
XFASM23_RS00740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XFASM23_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM23_RS00765	COG1272	protein, Hemolysin III
XFASM23_RS00770	COG0463	Glycosyl transferase, family 2
XFASM23_RS00775	COG0084	hydrolase, TatD family'
XFASM23_RS00805	COG0330	HflC and HflK could
XFASM23_RS00810	COG3956	TIGRFAM MazG family protein
XFASM23_RS00815	COG1218	3'(2'),5'-bisphosphate nucleotidase
XFASM23_RS00820	COG0494	nUDIX hydrolase
XFASM23_RS00830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XFASM23_RS00835	COG0513	Belongs to the DEAD box helicase family
XFASM23_RS00840	COG0720	synthase
XFASM23_RS00865	COG1981	membrane
XFASM23_RS00900	COG0512	Glutamine amidotransferase of anthranilate synthase
XFASM23_RS00935	COG0006	proline dipeptidase activity
XFASM23_RS00955	COG1862	Preprotein translocase
XFASM23_RS00960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFASM23_RS00965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XFASM23_RS00975	COG0617	tRNA 3'-terminal CCA addition
XFASM23_RS01015	COG0195	Participates in both transcription termination and antitermination
XFASM23_RS01045	COG1733	regulation of RNA biosynthetic process
XFASM23_RS01050	COG0702	epimerase
XFASM23_RS01100	COG2086	electron transfer activity
XFASM23_RS01130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFASM23_RS01160	COG0477	Major facilitator Superfamily
XFASM23_RS01180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XFASM23_RS01185	COG0671	phosphoesterase, PA-phosphatase related
XFASM23_RS01195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XFASM23_RS01200	COG0628	permease
XFASM23_RS01220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFASM23_RS01225	COG1090	epimerase
XFASM23_RS01230	COG0318	PFAM AMP-dependent synthetase and ligase
XFASM23_RS01250	COG1049	propionate catabolic process, 2-methylcitrate cycle
XFASM23_RS01270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFASM23_RS01305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFASM23_RS01335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XFASM23_RS01355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
XFASM23_RS01360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
XFASM23_RS01365	COG1034	ATP synthesis coupled electron transport
XFASM23_RS01400	COG1007	ATP synthesis coupled electron transport
XFASM23_RS01405	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM23_RS01410	COG2851	Citrate transporter
XFASM23_RS01425	COG0642	Histidine kinase
XFASM23_RS01445	COG0784	Response regulator, receiver
XFASM23_RS01445	COG2205	protein histidine kinase activity
XFASM23_RS01460	COG0281	malic enzyme
XFASM23_RS01460	COG0280	phosphate acetyltransferase
XFASM23_RS01470	COG0742	ribosomal rna small subunit methyltransferase
XFASM23_RS01485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XFASM23_RS01505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
XFASM23_RS01530	COG2166	iron-sulfur cluster assembly
XFASM23_RS01560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XFASM23_RS01635	COG1321	iron dependent repressor
XFASM23_RS01655	COG1946	Acyl-CoA thioesterase
XFASM23_RS01740	COG0575	Belongs to the CDS family
XFASM23_RS01830	COG0354	folic acid binding
XFASM23_RS01840	COG2009	succinate dehydrogenase
XFASM23_RS01845	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XFASM23_RS01855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XFASM23_RS01885	COG0811	peptide transport
XFASM23_RS01935	COG3093	addiction module antidote protein HigA
XFASM23_RS01945	COG2944	sequence-specific DNA binding
XFASM23_RS02010	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFASM23_RS02030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFASM23_RS02100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XFASM23_RS02105	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XFASM23_RS02125	COG1024	Enoyl-CoA hydratase
XFASM23_RS02130	COG0019	diaminopimelate decarboxylase activity
XFASM23_RS02150	COG0494	nUDIX hydrolase
XFASM23_RS02155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
XFASM23_RS02180	COG0312	modulator of DNA gyrase
XFASM23_RS02190	COG0312	modulator of DNA gyrase
XFASM23_RS02195	COG0583	DNA-binding transcription factor activity
XFASM23_RS02210	COG1064	alcohol dehydrogenase
XFASM23_RS02270	COG0356	it plays a direct role in the translocation of protons across the membrane
XFASM23_RS02380	COG0201	protein transport
XFASM23_RS02410	COG2960	long-chain fatty acid transporting porin activity
XFASM23_RS02415	COG0606	chelatase, subunit chli
XFASM23_RS02440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XFASM23_RS02505	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFASM23_RS02510	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XFASM23_RS02525	COG1187	pseudouridine synthase activity
XFASM23_RS02530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XFASM23_RS02555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFASM23_RS02560	COG0625	glutathione transferase activity
XFASM23_RS02570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XFASM23_RS02575	COG1217	gtp-binding protein TYPA
XFASM23_RS02600	COG0842	Transport permease protein
XFASM23_RS02605	COG1131	(ABC) transporter
XFASM23_RS02625	COG1643	Atp-dependent helicase
XFASM23_RS02635	COG1956	GAF domain-containing protein
XFASM23_RS02640	COG0729	surface antigen
XFASM23_RS02645	COG2911	Protein conserved in bacteria
XFASM23_RS02780	COG0668	transmembrane transport
XFASM23_RS02810	COG5297	Belongs to the glycosyl hydrolase family 6
XFASM23_RS02840	COG2733	membrane
XFASM23_RS02845	COG1253	flavin adenine dinucleotide binding
XFASM23_RS02910	COG0644	oxidoreductase
XFASM23_RS02910	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
XFASM23_RS02925	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XFASM23_RS02925	COG3218	ABC-type transport auxiliary lipoprotein component
XFASM23_RS02930	COG1127	ABC transporter
XFASM23_RS02935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFASM23_RS02955	COG1077	Cell shape determining protein MreB Mrl
XFASM23_RS02960	COG1792	Involved in formation and maintenance of cell shape
XFASM23_RS02965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XFASM23_RS02970	COG0768	penicillin binding
XFASM23_RS02975	COG0772	Belongs to the SEDS family
XFASM23_RS02985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFASM23_RS03005	COG2894	cell division
XFASM23_RS03030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XFASM23_RS03045	COG2353	YceI-like domain
XFASM23_RS03115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XFASM23_RS03120	COG4208	sulfate ABC transporter
XFASM23_RS03145	COG1846	Transcriptional regulator
XFASM23_RS03185	COG0741	lytic transglycosylase activity
XFASM23_RS03195	COG1999	signal sequence binding
XFASM23_RS03215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XFASM23_RS03250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XFASM23_RS03260	COG0514	ATP-dependent DNA helicase (RecQ)
XFASM23_RS03265	COG0783	Belongs to the Dps family
XFASM23_RS03270	COG1643	Atp-dependent helicase
XFASM23_RS03280	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XFASM23_RS03285	COG1845	cytochrome c oxidase, subunit III
XFASM23_RS03290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XFASM23_RS03295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XFASM23_RS03300	COG0142	geranyltranstransferase activity
XFASM23_RS03310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XFASM23_RS03330	COG2239	Acts as a magnesium transporter
XFASM23_RS03340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XFASM23_RS03375	COG1137	ATPase activity
XFASM23_RS03390	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XFASM23_RS03400	COG0271	Belongs to the BolA IbaG family
XFASM23_RS03440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFASM23_RS03450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XFASM23_RS03485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XFASM23_RS03515	COG0542	response to heat
XFASM23_RS03535	COG0492	ferredoxin-NADP+ reductase activity
XFASM23_RS03555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XFASM23_RS03570	COG4191	Histidine kinase
XFASM23_RS03575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XFASM23_RS03580	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM23_RS03610	COG1609	Transcriptional regulator
XFASM23_RS03615	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
XFASM23_RS03620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XFASM23_RS03625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XFASM23_RS03635	COG0726	polysaccharide deacetylase
XFASM23_RS03640	COG0297	glycogen (starch) synthase activity
XFASM23_RS03660	COG0719	Fe-S assembly protein
XFASM23_RS03665	COG0396	ATPase activity
XFASM23_RS03670	COG0719	Fe-S assembly protein
XFASM23_RS03675	COG1959	2 iron, 2 sulfur cluster binding
XFASM23_RS03725	COG0308	aminopeptidase N
XFASM23_RS03775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XFASM23_RS03800	COG1561	YicC-like family, N-terminal region
XFASM23_RS03815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XFASM23_RS03850	COG5295	Hep Hag repeat protein
XFASM23_RS03855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XFASM23_RS03860	COG1459	type II secretion system
XFASM23_RS03865	COG2165	general secretion pathway protein
XFASM23_RS03870	COG4970	Tfp pilus assembly protein FimT
XFASM23_RS03875	COG2165	general secretion pathway protein
XFASM23_RS03880	COG4795	General secretion pathway protein
XFASM23_RS03885	COG3156	type II secretion system protein K
XFASM23_RS03890	COG3166	PFAM Fimbrial assembly family protein
XFASM23_RS03905	COG1450	Type ii and iii secretion system protein
XFASM23_RS03920	COG3634	alkyl hydroperoxide reductase activity
XFASM23_RS03925	COG0583	DNA-binding transcription factor activity
XFASM23_RS03985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XFASM23_RS04010	COG0567	Dehydrogenase, E1 component
XFASM23_RS04015	COG2850	peptidyl-arginine hydroxylation
XFASM23_RS04035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFASM23_RS04130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFASM23_RS04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFASM23_RS04140	COG2902	Dehydrogenase
XFASM23_RS04180	COG2925	Exonuclease
XFASM23_RS04195	COG0025	NhaP-type Na H and K H
XFASM23_RS04215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XFASM23_RS04235	COG0006	proline dipeptidase activity
XFASM23_RS04245	COG0778	Nitroreductase
XFASM23_RS04270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XFASM23_RS04310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XFASM23_RS04320	COG0557	exoribonuclease II activity
XFASM23_RS04330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XFASM23_RS04345	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XFASM23_RS04350	COG1289	transmembrane transporter activity
XFASM23_RS04380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XFASM23_RS04390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XFASM23_RS04410	COG0596	Alpha beta hydrolase
XFASM23_RS04415	COG0727	PFAM Uncharacterised protein family (UPF0153)
XFASM23_RS04460	COG0840	transmembrane signaling receptor activity
XFASM23_RS04465	COG0784	Response regulator, receiver
XFASM23_RS04465	COG0643	Histidine kinase
XFASM23_RS04465	COG2198	Histidine kinase
XFASM23_RS04495	COG0285	dihydrofolate synthase activity
XFASM23_RS04505	COG0339	signal peptide processing
XFASM23_RS04525	COG1301	dicarboxylic acid transport
XFASM23_RS04530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XFASM23_RS04540	COG2091	lysine biosynthetic process via aminoadipic acid
XFASM23_RS04590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XFASM23_RS04635	COG0084	hydrolase, TatD family'
XFASM23_RS04650	COG0552	protein localization to endoplasmic reticulum
XFASM23_RS04690	COG0824	Thioesterase
XFASM23_RS04715	COG2885	chlorophyll binding
XFASM23_RS04725	COG0602	queuosine metabolic process
XFASM23_RS04745	COG0386	Belongs to the glutathione peroxidase family
XFASM23_RS04765	COG0406	alpha-ribazole phosphatase activity
XFASM23_RS05120	COG2369	cell adhesion
XFASM23_RS05225	COG0582	viral genome integration into host DNA
XFASM23_RS05230	COG3567	Phage-associated protein, HI1409 family
XFASM23_RS05235	COG5410	chromosome segregation
XFASM23_RS05260	COG3772	lysozyme
XFASM23_RS05295	COG3617	BRO family, N-terminal domain
XFASM23_RS05370	COG5532	Uncharacterized conserved protein (DUF2303)
XFASM23_RS05395	COG0629	single-stranded DNA binding
XFASM23_RS05405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFASM23_RS05410	COG3852	Histidine kinase
XFASM23_RS05415	COG2204	response regulator
XFASM23_RS05425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XFASM23_RS05430	COG0004	ammonium transporteR
XFASM23_RS05435	COG0347	Belongs to the P(II) protein family
XFASM23_RS05440	COG0174	glutamine synthetase
XFASM23_RS05450	COG2353	YceI-like domain
XFASM23_RS05505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XFASM23_RS05510	COG1764	response to oxidative stress
XFASM23_RS05515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFASM23_RS05560	COG1399	metal-binding, possibly nucleic acid-binding protein
XFASM23_RS05570	COG0714	Associated with various cellular activities
XFASM23_RS05590	COG0537	adenosine 5'-monophosphoramidase activity
XFASM23_RS05605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
XFASM23_RS05640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XFASM23_RS05665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XFASM23_RS05665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XFASM23_RS05715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XFASM23_RS05730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
XFASM23_RS05745	COG0251	oxidation-reduction process
XFASM23_RS05810	COG3077	Addiction module antitoxin, RelB DinJ family
XFASM23_RS05815	COG3041	Addiction module toxin RelE StbE family
XFASM23_RS05885	COG3772	lysozyme
XFASM23_RS05935	COG4197	protein conserved in bacteria, prophage-related
XFASM23_RS06045	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFASM23_RS06050	COG0392	lysyltransferase activity
XFASM23_RS06050	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
XFASM23_RS06065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XFASM23_RS06075	COG0463	Glycosyl transferase, family 2
XFASM23_RS06125	COG3275	phosphorelay sensor kinase activity
XFASM23_RS06130	COG0400	carboxylic ester hydrolase activity
XFASM23_RS06150	COG2226	methyltransferase
XFASM23_RS06175	COG2027	D-alanyl-D-alanine carboxypeptidase
XFASM23_RS06185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFASM23_RS06215	COG0386	Belongs to the glutathione peroxidase family
XFASM23_RS06220	COG1131	(ABC) transporter
XFASM23_RS06250	COG3657	addiction module killer protein
XFASM23_RS06255	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XFASM23_RS06350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XFASM23_RS06355	COG0488	(ABC) transporter
XFASM23_RS06365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
XFASM23_RS06375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XFASM23_RS06375	COG4651	solute:proton antiporter activity
XFASM23_RS06435	COG0859	PFAM glycosyl transferase family 9
XFASM23_RS06450	COG0631	protein serine/threonine phosphatase activity
XFASM23_RS06455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XFASM23_RS06475	COG2183	response to ionizing radiation
XFASM23_RS06490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XFASM23_RS06495	COG3118	belongs to the thioredoxin family
XFASM23_RS06535	COG2951	lytic endotransglycosylase activity
XFASM23_RS06540	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XFASM23_RS06685	COG0277	FAD linked oxidase domain protein
XFASM23_RS06690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XFASM23_RS06695	COG0531	amino acid
XFASM23_RS06700	COG0531	amino acid
XFASM23_RS06780	COG0527	aspartate kinase activity
XFASM23_RS06780	COG0460	homoserine dehydrogenase
XFASM23_RS06800	COG1686	Belongs to the peptidase S11 family
XFASM23_RS06825	COG4953	penicillin-binding protein 1C
XFASM23_RS06850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XFASM23_RS06915	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFASM23_RS06920	COG0823	Involved in the tonB-independent uptake of proteins
XFASM23_RS06920	COG1506	peptidase
XFASM23_RS06925	COG1297	OPT oligopeptide transporter protein
XFASM23_RS06950	COG0676	glucose-6-phosphate 1-epimerase activity
XFASM23_RS06960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XFASM23_RS06965	COG1335	isochorismatase
XFASM23_RS06970	COG0318	PFAM AMP-dependent synthetase and ligase
XFASM23_RS06980	COG0463	Glycosyl transferase, family 2
XFASM23_RS06995	COG1192	Involved in chromosome partitioning
XFASM23_RS07055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XFASM23_RS07105	COG0489	protein tyrosine kinase activity
XFASM23_RS07115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
XFASM23_RS07210	COG0077	Prephenate dehydratase
XFASM23_RS07210	COG1605	Chorismate mutase
XFASM23_RS07225	COG1668	transmembrane transport
XFASM23_RS07230	COG4555	ABC transporter
XFASM23_RS07255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XFASM23_RS07265	COG1605	Chorismate mutase
XFASM23_RS07265	COG0287	Prephenate dehydrogenase
XFASM23_RS07300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFASM23_RS07325	COG1278	Cold shock
XFASM23_RS07335	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XFASM23_RS07345	COG2954	triphosphatase activity
XFASM23_RS07360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
XFASM23_RS07365	COG0438	transferase activity, transferring glycosyl groups
XFASM23_RS07380	COG0438	transferase activity, transferring glycosyl groups
XFASM23_RS07440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XFASM23_RS07445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XFASM23_RS07460	COG1064	alcohol dehydrogenase
XFASM23_RS07475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFASM23_RS07485	COG0436	Aminotransferase
XFASM23_RS07570	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XFASM23_RS07570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XFASM23_RS07620	COG0196	riboflavin kinase activity
XFASM23_RS07625	COG0728	peptidoglycan biosynthetic process
XFASM23_RS07630	COG0268	Binds directly to 16S ribosomal RNA
XFASM23_RS07680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XFASM23_RS07695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XFASM23_RS07745	COG0395	ABC-type sugar transport system, permease component
XFASM23_RS07750	COG1175	transmembrane transport
XFASM23_RS07780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
XFASM23_RS07800	COG0436	Aminotransferase
XFASM23_RS07855	COG5434	Belongs to the glycosyl hydrolase 28 family
XFASM23_RS07875	COG0402	S-adenosylhomocysteine deaminase activity
XFASM23_RS07885	COG1509	lysine 2,3-aminomutase activity
XFASM23_RS07920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XFASM23_RS07925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
XFASM23_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
XFASM23_RS07980	COG0142	geranyltranstransferase activity
XFASM23_RS08000	COG1301	dicarboxylic acid transport
XFASM23_RS08010	COG0791	NLP P60 protein
XFASM23_RS08015	COG0791	NLP P60 protein
XFASM23_RS08025	COG2311	Membrane
XFASM23_RS08035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XFASM23_RS08085	COG0352	thiamine-phosphate diphosphorylase activity
XFASM23_RS08085	COG0351	phosphomethylpyrimidine kinase
XFASM23_RS08095	COG1324	tolerance protein
XFASM23_RS08130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFASM23_RS08135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XFASM23_RS08140	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XFASM23_RS08155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
XFASM23_RS08175	COG4774	siderophore transport
XFASM23_RS08200	COG1477	protein flavinylation
XFASM23_RS08205	COG1555	photosystem II stabilization
XFASM23_RS08210	COG3178	'Phosphotransferase
XFASM23_RS08215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
XFASM23_RS08225	COG0628	permease
XFASM23_RS08245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XFASM23_RS08265	COG3590	peptidase
XFASM23_RS08315	COG0805	protein transport
XFASM23_RS08330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XFASM23_RS08330	COG0519	Catalyzes the synthesis of GMP from XMP
XFASM23_RS08340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
XFASM23_RS08360	COG3107	peptidoglycan biosynthetic process
XFASM23_RS08385	COG2878	Part of a membrane complex involved in electron transport
XFASM23_RS08455	COG0629	single-stranded DNA binding
XFASM23_RS08480	COG0827	DNA restriction-modification system
XFASM23_RS08485	COG0827	DNA restriction-modification system
XFASM23_RS08520	COG4968	Prepilin-type N-terminal cleavage methylation domain
XFASM23_RS08525	COG1611	Belongs to the LOG family
XFASM23_RS08530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
XFASM23_RS08535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XFASM23_RS08545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XFASM23_RS08575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XFASM23_RS08590	COG0330	HflC and HflK could
XFASM23_RS08595	COG0330	HflC and HflK could
XFASM23_RS08600	COG0604	alcohol dehydrogenase
XFASM23_RS08630	COG1183	phosphatidylcholine synthase activity
XFASM23_RS08650	COG0668	transmembrane transport
XFASM23_RS08655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XFASM23_RS08670	COG1610	YqeY-like protein
XFASM23_RS08680	COG0358	DNA primase activity
XFASM23_RS08720	COG1074	ATP-dependent DNA helicase activity
XFASM23_RS08725	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XFASM23_RS08730	COG1127	ABC transporter
XFASM23_RS08735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XFASM23_RS08755	COG2853	Lipoprotein
XFASM23_RS08770	COG1116	anion transmembrane transporter activity
XFASM23_RS08780	COG0531	amino acid
XFASM23_RS08785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XFASM23_RS08790	COG0861	Integral membrane protein TerC family
XFASM23_RS08820	COG2193	ferroxidase activity
XFASM23_RS08905	COG2194	sulfuric ester hydrolase activity
XFASM23_RS08945	COG0667	Aldo Keto reductase
XFASM23_RS08950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XFASM23_RS08960	COG0305	Participates in initiation and elongation during chromosome replication
XFASM23_RS08980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XFASM23_RS08990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XFASM23_RS08995	COG0277	FAD linked oxidase domain protein
XFASM23_RS09020	COG4206	TonB-dependent receptor
XFASM23_RS09125	COG3617	BRO family, N-terminal domain
XFASM23_RS09200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XFASM23_RS09205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XFASM23_RS09210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
XFASM23_RS09225	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XFASM23_RS09250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFASM23_RS09250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XFASM23_RS09270	COG0488	(ABC) transporter
XFASM23_RS09280	COG3011	Protein conserved in bacteria
XFASM23_RS09305	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
XFASM23_RS09305	COG1918	ferrous iron import across plasma membrane
XFASM23_RS09315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XFASM23_RS09340	COG0758	DNA mediated transformation
XFASM23_RS09385	COG2969	positive regulation of protein catabolic process
XFASM23_RS09390	COG0625	glutathione transferase activity
XFASM23_RS09395	COG2857	Cytochrome c1
XFASM23_RS09400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
XFASM23_RS09405	COG0723	plastoquinol--plastocyanin reductase activity
XFASM23_RS09410	COG0741	lytic transglycosylase activity
XFASM23_RS09420	COG1702	phosphate starvation-inducible protein PhoH
XFASM23_RS09435	COG4535	Mg2 and Co2 transporter CorC
XFASM23_RS09445	COG0598	Magnesium transport protein CorA
XFASM23_RS09555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XFASM23_RS09565	COG1199	ATP-dependent helicase activity
XFASM23_RS09575	COG0288	reversible hydration of carbon dioxide
XFASM23_RS09600	COG2011	ABC-type metal ion transport system permease component
XFASM23_RS09615	COG0508	dehydrogenase complex catalyzes the overall conversion of
XFASM23_RS09620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XFASM23_RS09630	COG0626	cystathionine gamma-synthase activity
XFASM23_RS09635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
XFASM23_RS09640	COG0739	heme binding
XFASM23_RS09660	COG1238	metal cluster binding
XFASM23_RS09675	COG5002	protein histidine kinase activity
XFASM23_RS09700	COG3858	chitin binding
XFASM23_RS09700	COG1388	LysM domain
XFASM23_RS09705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
XFASM23_RS09715	COG1472	Belongs to the glycosyl hydrolase 3 family
XFASM23_RS09730	COG3537	Alpha-1,2-mannosidase
XFASM23_RS09760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFASM23_RS09765	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XFASM23_RS09805	COG0469	pyruvate kinase activity
XFASM23_RS09825	COG0735	belongs to the Fur family
XFASM23_RS09835	COG5297	Belongs to the glycosyl hydrolase family 6
XFASM23_RS09835	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFASM23_RS09860	COG4305	rare lipoprotein A
XFASM23_RS09870	COG0739	heme binding
XFASM23_RS09885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XFASM23_RS09895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XFASM23_RS09925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XFASM23_RS09940	COG3116	cell division
XFASM23_RS09955	COG3273	potassium ion transport
XFASM23_RS09955	COG0471	metal ion transport
XFASM23_RS10010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XFASM23_RS10070	COG0860	N-Acetylmuramoyl-L-alanine amidase
XFASM23_RS10075	COG0802	atpase or kinase
XFASM23_RS10080	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XFASM23_RS10080	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XFASM23_RS10190	COG0745	RESPONSE REGULATOR receiver
XFASM23_RS10195	COG0642	Histidine kinase
XFASM23_RS10205	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XFASM23_RS10250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XFASM23_RS10260	COG2831	hemolysin activation secretion protein
XFASM23_RS10285	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XFASM23_RS10330	COG0316	Belongs to the HesB IscA family
XFASM23_RS10365	COG0697	spore germination
XFASM23_RS10370	COG0671	phosphoesterase, PA-phosphatase related
XFASM23_RS10385	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
XFASM23_RS10405	COG1132	(ABC) transporter
XFASM23_RS10415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XFASM23_RS10420	COG1538	Outer membrane efflux protein
XFASM23_RS10445	COG0745	RESPONSE REGULATOR receiver
XFASM23_RS10450	COG4783	chaperone-mediated protein folding
XFASM23_RS10460	COG0473	3-isopropylmalate dehydrogenase activity
XFASM23_RS10470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XFASM23_RS10475	COG3083	sulfuric ester hydrolase activity
XFASM23_RS10480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
XFASM23_RS10505	COG0564	pseudouridine synthase activity
XFASM23_RS10510	COG1530	ribonuclease E activity
XFASM23_RS10515	COG2197	response regulator
XFASM23_RS10535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XFASM23_RS10550	COG0488	(ABC) transporter
XFASM23_RS10565	COG1278	Cold shock
XFASM23_RS10665	COG0012	GTP binding
XFASM23_RS10750	COG2095	MarC family integral membrane protein
XFASM23_RS10755	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XFASM23_RS10785	COG2132	Multicopper oxidase
XFASM23_RS10795	COG0210	DNA helicase
XFASM23_RS10805	COG0616	signal peptide processing
XFASM23_RS10825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XFASM23_RS10840	COG2201	protein-glutamate methylesterase activity
XFASM23_RS10845	COG2177	Part of the ABC transporter FtsEX involved in
XFASM23_RS10850	COG2884	Cell division ATP-binding protein ftsE
XFASM23_RS10860	COG3118	belongs to the thioredoxin family
XFASM23_RS10865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XFASM23_RS10875	COG0793	Belongs to the peptidase S41A family
XFASM23_RS10880	COG4942	peptidase
XFASM23_RS10895	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
XFASM23_RS10900	COG0493	'glutamate synthase
XFASM23_RS10905	COG0070	glutamate synthase
XFASM23_RS10905	COG0069	glutamate synthase activity
XFASM23_RS10905	COG0067	glutamate synthase
XFASM23_RS10955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
XFASM23_RS11005	COG4942	peptidase
XFASM23_RS11135	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XFASM23_RS11140	COG3657	addiction module killer protein
XFASM23_RS11520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XFASM23_RS11535	COG3617	BRO family, N-terminal domain