locus-tag	class	description
P303_RS00210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
P303_RS00220	COG0642	Histidine kinase
P303_RS00225	COG0745	RESPONSE REGULATOR receiver
P303_RS00250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
P303_RS00330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
P303_RS00330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
P303_RS00335	COG0802	atpase or kinase
P303_RS00340	COG0860	N-Acetylmuramoyl-L-alanine amidase
P303_RS00400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
P303_RS00450	COG3273	potassium ion transport
P303_RS00450	COG0471	metal ion transport
P303_RS00470	COG3116	cell division
P303_RS00485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
P303_RS00525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
P303_RS00540	COG0739	heme binding
P303_RS00550	COG4305	rare lipoprotein A
P303_RS00565	COG0612	Peptidase, M16
P303_RS00575	COG5297	Belongs to the glycosyl hydrolase family 6
P303_RS00575	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
P303_RS00585	COG0735	belongs to the Fur family
P303_RS00605	COG0469	pyruvate kinase activity
P303_RS00650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
P303_RS00655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
P303_RS00680	COG3537	Alpha-1,2-mannosidase
P303_RS00695	COG1472	Belongs to the glycosyl hydrolase 3 family
P303_RS00705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
P303_RS00710	COG1388	LysM domain
P303_RS00710	COG3858	chitin binding
P303_RS00735	COG5002	protein histidine kinase activity
P303_RS00750	COG1238	metal cluster binding
P303_RS00770	COG0739	heme binding
P303_RS00775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
P303_RS00780	COG0626	cystathionine gamma-synthase activity
P303_RS00790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
P303_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
P303_RS00810	COG2011	ABC-type metal ion transport system permease component
P303_RS00835	COG0288	reversible hydration of carbon dioxide
P303_RS00850	COG2166	iron-sulfur cluster assembly
P303_RS00880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
P303_RS00975	COG1914	H( )-stimulated, divalent metal cation uptake system
P303_RS00990	COG1946	Acyl-CoA thioesterase
P303_RS01080	COG0575	Belongs to the CDS family
P303_RS01110	COG0528	UMP kinase activity
P303_RS01135	COG0800	Aldolase
P303_RS01165	COG0354	folic acid binding
P303_RS01175	COG2009	succinate dehydrogenase
P303_RS01180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
P303_RS01190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
P303_RS01220	COG0811	peptide transport
P303_RS01265	COG3077	Addiction module antitoxin, RelB DinJ family
P303_RS01335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
P303_RS01355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
P303_RS01425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
P303_RS01430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
P303_RS01450	COG1024	Enoyl-CoA hydratase
P303_RS01455	COG0527	aspartate kinase activity
P303_RS01475	COG0494	nUDIX hydrolase
P303_RS01480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
P303_RS01505	COG0312	modulator of DNA gyrase
P303_RS01515	COG0312	modulator of DNA gyrase
P303_RS01520	COG0583	DNA-binding transcription factor activity
P303_RS01535	COG1064	alcohol dehydrogenase
P303_RS01590	COG0356	it plays a direct role in the translocation of protons across the membrane
P303_RS01690	COG0201	protein transport
P303_RS01720	COG2960	long-chain fatty acid transporting porin activity
P303_RS01725	COG0606	chelatase, subunit chli
P303_RS01735	COG5380	lipid catabolic process
P303_RS01745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
P303_RS01770	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
P303_RS01805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
P303_RS01810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
P303_RS01825	COG1187	pseudouridine synthase activity
P303_RS01830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
P303_RS01850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
P303_RS01855	COG0625	glutathione transferase activity
P303_RS01865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
P303_RS01870	COG1217	gtp-binding protein TYPA
P303_RS01895	COG0842	Transport permease protein
P303_RS01900	COG1131	(ABC) transporter
P303_RS01920	COG1643	Atp-dependent helicase
P303_RS01930	COG1956	GAF domain-containing protein
P303_RS01935	COG0729	surface antigen
P303_RS01940	COG2911	Protein conserved in bacteria
P303_RS02030	COG0668	transmembrane transport
P303_RS02060	COG5297	Belongs to the glycosyl hydrolase family 6
P303_RS02065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
P303_RS02095	COG2733	membrane
P303_RS02100	COG1253	flavin adenine dinucleotide binding
P303_RS02165	COG0644	oxidoreductase
P303_RS02165	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
P303_RS02180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
P303_RS02180	COG3218	ABC-type transport auxiliary lipoprotein component
P303_RS02185	COG1127	ABC transporter
P303_RS02190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
P303_RS02210	COG1077	Cell shape determining protein MreB Mrl
P303_RS02215	COG1792	Involved in formation and maintenance of cell shape
P303_RS02220	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
P303_RS02225	COG0768	penicillin binding
P303_RS02230	COG0772	Belongs to the SEDS family
P303_RS02240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
P303_RS02260	COG2894	cell division
P303_RS02280	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
P303_RS02295	COG2353	YceI-like domain
P303_RS02360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
P303_RS02365	COG4208	sulfate ABC transporter
P303_RS02390	COG1846	Transcriptional regulator
P303_RS02415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
P303_RS02425	COG0741	lytic transglycosylase activity
P303_RS02450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
P303_RS02485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
P303_RS02495	COG0514	ATP-dependent DNA helicase (RecQ)
P303_RS02500	COG0783	Belongs to the Dps family
P303_RS02505	COG1643	Atp-dependent helicase
P303_RS02550	COG3617	BRO family, N-terminal domain
P303_RS02655	COG3772	lysozyme
P303_RS02725	COG2944	sequence-specific DNA binding
P303_RS02735	COG3093	addiction module antidote protein HigA
P303_RS02800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
P303_RS02805	COG1845	cytochrome c oxidase, subunit III
P303_RS02810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
P303_RS02815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
P303_RS02820	COG0142	geranyltranstransferase activity
P303_RS02850	COG2239	Acts as a magnesium transporter
P303_RS02860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
P303_RS02895	COG1137	ATPase activity
P303_RS02910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
P303_RS02920	COG0271	Belongs to the BolA IbaG family
P303_RS02955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
P303_RS02965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
P303_RS02980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
P303_RS03000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
P303_RS03030	COG0542	response to heat
P303_RS03050	COG0492	ferredoxin-NADP+ reductase activity
P303_RS03070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
P303_RS03080	COG4191	Histidine kinase
P303_RS03085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
P303_RS03090	COG1028	Short-chain dehydrogenase reductase Sdr
P303_RS03120	COG1609	Transcriptional regulator
P303_RS03125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
P303_RS03130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
P303_RS03135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
P303_RS03140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
P303_RS03145	COG0726	polysaccharide deacetylase
P303_RS03150	COG0297	glycogen (starch) synthase activity
P303_RS03170	COG0719	Fe-S assembly protein
P303_RS03175	COG0396	ATPase activity
P303_RS03180	COG0719	Fe-S assembly protein
P303_RS03185	COG1959	2 iron, 2 sulfur cluster binding
P303_RS03235	COG0308	aminopeptidase N
P303_RS03285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
P303_RS03300	COG1758	RNA polymerase activity
P303_RS03310	COG1561	YicC-like family, N-terminal region
P303_RS03325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
P303_RS03365	COG5295	Hep Hag repeat protein
P303_RS03370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
P303_RS03375	COG1459	type II secretion system
P303_RS03380	COG2165	general secretion pathway protein
P303_RS03385	COG4970	Tfp pilus assembly protein FimT
P303_RS03390	COG2165	general secretion pathway protein
P303_RS03395	COG4795	General secretion pathway protein
P303_RS03400	COG3156	type II secretion system protein K
P303_RS03405	COG3166	PFAM Fimbrial assembly family protein
P303_RS03420	COG1450	Type ii and iii secretion system protein
P303_RS03435	COG3634	alkyl hydroperoxide reductase activity
P303_RS03440	COG0583	DNA-binding transcription factor activity
P303_RS03500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
P303_RS03525	COG0567	Dehydrogenase, E1 component
P303_RS03530	COG2850	peptidyl-arginine hydroxylation
P303_RS03630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
P303_RS03635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
P303_RS03640	COG2902	Dehydrogenase
P303_RS03735	COG0675	Transposase, IS605 OrfB family
P303_RS03755	COG3657	addiction module killer protein
P303_RS03790	COG3609	addiction module antidote protein, CC2985 family
P303_RS03800	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
P303_RS03825	COG2925	Exonuclease
P303_RS03840	COG0025	NhaP-type Na H and K H
P303_RS03860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
P303_RS03880	COG0006	proline dipeptidase activity
P303_RS03890	COG0778	Nitroreductase
P303_RS03920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
P303_RS03960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
P303_RS03970	COG0557	exoribonuclease II activity
P303_RS03980	COG0582	viral genome integration into host DNA
P303_RS03985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
P303_RS04000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
P303_RS04005	COG1289	transmembrane transporter activity
P303_RS04025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
P303_RS04035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
P303_RS04055	COG0596	Alpha beta hydrolase
P303_RS04060	COG0727	PFAM Uncharacterised protein family (UPF0153)
P303_RS04105	COG0840	transmembrane signaling receptor activity
P303_RS04110	COG0643	Histidine kinase
P303_RS04110	COG0784	Response regulator, receiver
P303_RS04110	COG2198	Histidine kinase
P303_RS04140	COG0285	dihydrofolate synthase activity
P303_RS04150	COG0339	signal peptide processing
P303_RS04170	COG1301	dicarboxylic acid transport
P303_RS04175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
P303_RS04185	COG2091	lysine biosynthetic process via aminoadipic acid
P303_RS04240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
P303_RS04280	COG0084	hydrolase, TatD family'
P303_RS04295	COG0552	protein localization to endoplasmic reticulum
P303_RS04335	COG0824	Thioesterase
P303_RS04360	COG2885	chlorophyll binding
P303_RS04370	COG0602	queuosine metabolic process
P303_RS04390	COG0386	Belongs to the glutathione peroxidase family
P303_RS04410	COG0406	alpha-ribazole phosphatase activity
P303_RS04675	COG3852	Histidine kinase
P303_RS04680	COG2204	response regulator
P303_RS04690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
P303_RS04695	COG0004	ammonium transporteR
P303_RS04700	COG0347	Belongs to the P(II) protein family
P303_RS04705	COG0174	glutamine synthetase
P303_RS04710	COG1968	undecaprenyl-diphosphatase activity
P303_RS04715	COG2353	YceI-like domain
P303_RS04820	COG3772	lysozyme
P303_RS04840	COG3617	BRO family, N-terminal domain
P303_RS04945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
P303_RS04950	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
P303_RS04950	COG0392	lysyltransferase activity
P303_RS04965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
P303_RS04975	COG0463	Glycosyl transferase, family 2
P303_RS05020	COG3275	phosphorelay sensor kinase activity
P303_RS05025	COG0400	carboxylic ester hydrolase activity
P303_RS05045	COG2226	methyltransferase
P303_RS05100	COG0386	Belongs to the glutathione peroxidase family
P303_RS05105	COG1131	(ABC) transporter
P303_RS05235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
P303_RS05240	COG0488	(ABC) transporter
P303_RS05260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
P303_RS05260	COG4651	solute:proton antiporter activity
P303_RS05320	COG0859	PFAM glycosyl transferase family 9
P303_RS05335	COG0631	protein serine/threonine phosphatase activity
P303_RS05340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
P303_RS05345	COG0328	RNA-DNA hybrid ribonuclease activity
P303_RS05360	COG2183	response to ionizing radiation
P303_RS05375	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
P303_RS05380	COG3118	belongs to the thioredoxin family
P303_RS05425	COG2951	lytic endotransglycosylase activity
P303_RS05430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
P303_RS05515	COG0277	FAD linked oxidase domain protein
P303_RS05520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
P303_RS05525	COG0531	amino acid
P303_RS05530	COG0531	amino acid
P303_RS05540	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
P303_RS05610	COG0460	homoserine dehydrogenase
P303_RS05610	COG0527	aspartate kinase activity
P303_RS05615	COG0540	Belongs to the ATCase OTCase family
P303_RS05630	COG1686	Belongs to the peptidase S11 family
P303_RS05655	COG4953	penicillin-binding protein 1C
P303_RS05685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
P303_RS05750	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
P303_RS05755	COG0823	Involved in the tonB-independent uptake of proteins
P303_RS05755	COG1506	peptidase
P303_RS05760	COG1297	OPT oligopeptide transporter protein
P303_RS05785	COG0676	glucose-6-phosphate 1-epimerase activity
P303_RS05795	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
P303_RS05800	COG1335	isochorismatase
P303_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
P303_RS05815	COG0463	Glycosyl transferase, family 2
P303_RS05830	COG1192	Involved in chromosome partitioning
P303_RS05890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
P303_RS05935	COG0489	protein tyrosine kinase activity
P303_RS05945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
P303_RS06045	COG1605	Chorismate mutase
P303_RS06045	COG0077	Prephenate dehydratase
P303_RS06050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
P303_RS06060	COG1668	transmembrane transport
P303_RS06065	COG4555	ABC transporter
P303_RS06090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
P303_RS06100	COG1605	Chorismate mutase
P303_RS06100	COG0287	Prephenate dehydrogenase
P303_RS06135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
P303_RS06160	COG1278	Cold shock
P303_RS06170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
P303_RS06180	COG2954	triphosphatase activity
P303_RS06195	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
P303_RS06200	COG0438	transferase activity, transferring glycosyl groups
P303_RS06215	COG0438	transferase activity, transferring glycosyl groups
P303_RS06275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
P303_RS06280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
P303_RS06295	COG1064	alcohol dehydrogenase
P303_RS06310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
P303_RS06320	COG0436	Aminotransferase
P303_RS06435	COG0196	riboflavin kinase activity
P303_RS06440	COG0728	peptidoglycan biosynthetic process
P303_RS06445	COG0268	Binds directly to 16S ribosomal RNA
P303_RS06465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
P303_RS06495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
P303_RS06510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
P303_RS06560	COG0395	ABC-type sugar transport system, permease component
P303_RS06565	COG1175	transmembrane transport
P303_RS06590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
P303_RS06610	COG0436	Aminotransferase
P303_RS06630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
P303_RS06640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
P303_RS06690	COG0402	S-adenosylhomocysteine deaminase activity
P303_RS06700	COG1509	lysine 2,3-aminomutase activity
P303_RS06735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
P303_RS06740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
P303_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
P303_RS06800	COG0142	geranyltranstransferase activity
P303_RS06810	COG0037	tRNA processing
P303_RS06820	COG1301	dicarboxylic acid transport
P303_RS06830	COG0791	NLP P60 protein
P303_RS06835	COG0791	NLP P60 protein
P303_RS06845	COG2311	Membrane
P303_RS06860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
P303_RS06910	COG0352	thiamine-phosphate diphosphorylase activity
P303_RS06910	COG0351	phosphomethylpyrimidine kinase
P303_RS06920	COG1324	tolerance protein
P303_RS06955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
P303_RS06960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
P303_RS06965	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
P303_RS06980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
P303_RS07000	COG4774	siderophore transport
P303_RS07025	COG1477	protein flavinylation
P303_RS07030	COG1555	photosystem II stabilization
P303_RS07035	COG3178	'Phosphotransferase
P303_RS07040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
P303_RS07050	COG0628	permease
P303_RS07065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
P303_RS07085	COG3590	peptidase
P303_RS07150	COG0519	Catalyzes the synthesis of GMP from XMP
P303_RS07150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
P303_RS07160	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
P303_RS07180	COG3107	peptidoglycan biosynthetic process
P303_RS07200	COG2878	Part of a membrane complex involved in electron transport
P303_RS07285	COG0629	single-stranded DNA binding
P303_RS07310	COG0827	DNA restriction-modification system
P303_RS07315	COG0827	DNA restriction-modification system
P303_RS07395	COG5449	Phage conserved hypothetical protein BR0599
P303_RS07435	COG3772	lysozyme
P303_RS07510	COG0629	single-stranded DNA binding
P303_RS07535	COG0827	DNA restriction-modification system
P303_RS07540	COG0827	DNA restriction-modification system
P303_RS07585	COG1611	Belongs to the LOG family
P303_RS07590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
P303_RS07595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
P303_RS07605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
P303_RS07635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
P303_RS07650	COG0330	HflC and HflK could
P303_RS07655	COG0330	HflC and HflK could
P303_RS07660	COG0604	alcohol dehydrogenase
P303_RS07690	COG1183	phosphatidylcholine synthase activity
P303_RS07710	COG0668	transmembrane transport
P303_RS07715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
P303_RS07730	COG1610	YqeY-like protein
P303_RS07740	COG0358	DNA primase activity
P303_RS07780	COG1074	ATP-dependent DNA helicase activity
P303_RS07785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
P303_RS07790	COG1127	ABC transporter
P303_RS07795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
P303_RS07815	COG2853	Lipoprotein
P303_RS07830	COG1116	anion transmembrane transporter activity
P303_RS07840	COG0531	amino acid
P303_RS07845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
P303_RS07850	COG0861	Integral membrane protein TerC family
P303_RS07885	COG2193	ferroxidase activity
P303_RS07970	COG2194	sulfuric ester hydrolase activity
P303_RS08010	COG0667	Aldo Keto reductase
P303_RS08015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
P303_RS08025	COG0305	Participates in initiation and elongation during chromosome replication
P303_RS08045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
P303_RS08055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
P303_RS08060	COG0277	FAD linked oxidase domain protein
P303_RS08085	COG4206	TonB-dependent receptor
P303_RS08115	COG3657	addiction module killer protein
P303_RS08120	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
P303_RS08150	COG3657	addiction module killer protein
P303_RS08155	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
P303_RS08220	COG2369	cell adhesion
P303_RS08250	COG5410	chromosome segregation
P303_RS08275	COG3772	lysozyme
P303_RS08300	COG0305	Participates in initiation and elongation during chromosome replication
P303_RS08315	COG3617	BRO family, N-terminal domain
P303_RS08435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
P303_RS08485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
P303_RS08490	COG1764	response to oxidative stress
P303_RS08495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
P303_RS08530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
P303_RS08540	COG1399	metal-binding, possibly nucleic acid-binding protein
P303_RS08550	COG0714	Associated with various cellular activities
P303_RS08570	COG0537	adenosine 5'-monophosphoramidase activity
P303_RS08620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
P303_RS08645	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
P303_RS08645	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
P303_RS08700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
P303_RS08715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
P303_RS08730	COG0251	oxidation-reduction process
P303_RS08830	COG3772	lysozyme
P303_RS08920	COG3617	BRO family, N-terminal domain
P303_RS08985	COG3657	addiction module killer protein
P303_RS08990	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
P303_RS09020	COG3657	addiction module killer protein
P303_RS09025	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
P303_RS09090	COG2369	cell adhesion
P303_RS09120	COG5410	chromosome segregation
P303_RS09145	COG3772	lysozyme
P303_RS09185	COG3617	BRO family, N-terminal domain
P303_RS09190	COG3617	BRO family, N-terminal domain
P303_RS09195	COG3617	BRO family, N-terminal domain
P303_RS09280	COG5532	Uncharacterized conserved protein (DUF2303)
P303_RS09295	COG3617	BRO family, N-terminal domain
P303_RS09300	COG0629	single-stranded DNA binding
P303_RS09340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
P303_RS09345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
P303_RS09350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
P303_RS09365	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
P303_RS09390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
P303_RS09390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
P303_RS09410	COG0488	(ABC) transporter
P303_RS09420	COG3011	Protein conserved in bacteria
P303_RS09445	COG1918	ferrous iron import across plasma membrane
P303_RS09445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
P303_RS09455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
P303_RS09480	COG0758	DNA mediated transformation
P303_RS09525	COG2969	positive regulation of protein catabolic process
P303_RS09530	COG0625	glutathione transferase activity
P303_RS09535	COG2857	Cytochrome c1
P303_RS09540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
P303_RS09545	COG0723	plastoquinol--plastocyanin reductase activity
P303_RS09550	COG0741	lytic transglycosylase activity
P303_RS09560	COG1702	phosphate starvation-inducible protein PhoH
P303_RS09575	COG4535	Mg2 and Co2 transporter CorC
P303_RS09585	COG0598	Magnesium transport protein CorA
P303_RS09640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
P303_RS09650	COG1199	ATP-dependent helicase activity
P303_RS09675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
P303_RS09695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
P303_RS09710	COG0742	ribosomal rna small subunit methyltransferase
P303_RS09720	COG0281	malic enzyme
P303_RS09720	COG0280	phosphate acetyltransferase
P303_RS09735	COG2205	protein histidine kinase activity
P303_RS09735	COG0784	Response regulator, receiver
P303_RS09750	COG0642	Histidine kinase
P303_RS09765	COG2851	Citrate transporter
P303_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
P303_RS09775	COG1007	ATP synthesis coupled electron transport
P303_RS09810	COG1034	ATP synthesis coupled electron transport
P303_RS09815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
P303_RS09820	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
P303_RS09840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
P303_RS09865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
P303_RS09895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
P303_RS09925	COG1049	propionate catabolic process, 2-methylcitrate cycle
P303_RS09945	COG0318	PFAM AMP-dependent synthetase and ligase
P303_RS09950	COG1090	epimerase
P303_RS09955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
P303_RS09975	COG0628	permease
P303_RS09980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
P303_RS09990	COG0671	phosphoesterase, PA-phosphatase related
P303_RS09995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
P303_RS10015	COG0477	Major facilitator Superfamily
P303_RS10050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
P303_RS10080	COG2086	electron transfer activity
P303_RS10130	COG0702	epimerase
P303_RS10135	COG1733	regulation of RNA biosynthetic process
P303_RS10165	COG0195	Participates in both transcription termination and antitermination
P303_RS10210	COG0617	tRNA 3'-terminal CCA addition
P303_RS10220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
P303_RS10225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
P303_RS10230	COG1862	Preprotein translocase
P303_RS10255	COG0006	proline dipeptidase activity
P303_RS10290	COG0512	Glutamine amidotransferase of anthranilate synthase
P303_RS10325	COG1981	membrane
P303_RS10350	COG0720	synthase
P303_RS10355	COG0513	Belongs to the DEAD box helicase family
P303_RS10360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
P303_RS10370	COG0494	nUDIX hydrolase
P303_RS10375	COG1218	3'(2'),5'-bisphosphate nucleotidase
P303_RS10380	COG3956	TIGRFAM MazG family protein
P303_RS10385	COG0330	HflC and HflK could
P303_RS10415	COG0084	hydrolase, TatD family'
P303_RS10420	COG0463	Glycosyl transferase, family 2
P303_RS10425	COG1272	protein, Hemolysin III
P303_RS10435	COG1028	Short-chain dehydrogenase reductase Sdr
P303_RS10450	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
P303_RS10485	COG0739	heme binding
P303_RS10495	COG2223	nitrite transmembrane transporter activity
P303_RS10545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
P303_RS10555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
P303_RS10575	COG4221	oxidoreductase activity
P303_RS10660	COG0339	signal peptide processing
P303_RS10675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
P303_RS10700	COG0367	asparagine synthase
P303_RS10710	COG1393	Belongs to the ArsC family
P303_RS10750	COG1519	Transferase
P303_RS10755	COG1560	Kdo2-lipid A biosynthetic process
P303_RS10785	COG1534	Rna-binding protein
P303_RS10805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
P303_RS10820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
P303_RS10825	COG0477	Major facilitator Superfamily
P303_RS10830	COG1546	Belongs to the CinA family
P303_RS10835	COG3539	Fimbrial protein
P303_RS10840	COG3121	Chaperone
P303_RS10870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
P303_RS10880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
P303_RS10920	COG1752	Esterase of the alpha-beta hydrolase superfamily
P303_RS10930	COG1040	competence protein
P303_RS10955	COG0210	DNA helicase
P303_RS10960	COG0439	Biotin carboxylase
P303_RS10965	COG0511	ligase activity, forming carbon-carbon bonds
P303_RS10975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
P303_RS10985	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
P303_RS11055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
P303_RS11115	COG0501	Belongs to the peptidase M48B family
P303_RS11125	COG0187	DNA topoisomerase II activity
P303_RS11140	COG0592	DNA-directed DNA polymerase activity
P303_RS11285	COG0732	type I restriction modification DNA specificity domain
P303_RS11360	COG0067	glutamate synthase
P303_RS11360	COG0069	glutamate synthase activity
P303_RS11360	COG0070	glutamate synthase
P303_RS11365	COG0493	'glutamate synthase
P303_RS11370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
P303_RS11385	COG4942	peptidase
P303_RS11390	COG0793	Belongs to the peptidase S41A family
P303_RS11400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
P303_RS11405	COG3118	belongs to the thioredoxin family
P303_RS11415	COG2884	Cell division ATP-binding protein ftsE
P303_RS11420	COG2177	Part of the ABC transporter FtsEX involved in
P303_RS11425	COG2201	protein-glutamate methylesterase activity
P303_RS11440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
P303_RS11465	COG0616	signal peptide processing
P303_RS11475	COG0210	DNA helicase
P303_RS11485	COG2132	Multicopper oxidase
P303_RS11515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
P303_RS11520	COG2095	MarC family integral membrane protein
P303_RS11705	COG1278	Cold shock
P303_RS11720	COG0488	(ABC) transporter
P303_RS11735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
P303_RS11750	COG2197	response regulator
P303_RS11755	COG1530	ribonuclease E activity
P303_RS11760	COG0564	pseudouridine synthase activity
P303_RS11780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
P303_RS11785	COG3083	sulfuric ester hydrolase activity
P303_RS11790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
P303_RS11800	COG0473	3-isopropylmalate dehydrogenase activity
P303_RS11810	COG4783	chaperone-mediated protein folding
P303_RS11815	COG0745	RESPONSE REGULATOR receiver
P303_RS11840	COG1538	Outer membrane efflux protein
P303_RS11845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
P303_RS11855	COG1132	(ABC) transporter
P303_RS11870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
P303_RS11875	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
P303_RS11890	COG0671	phosphoesterase, PA-phosphatase related
P303_RS11895	COG0697	spore germination
P303_RS11930	COG0316	Belongs to the HesB IscA family
P303_RS11940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
P303_RS11975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
P303_RS12010	COG2831	hemolysin activation secretion protein
P303_RS12020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
P303_RS12050	COG3617	BRO family, N-terminal domain