locus-tag	class	description
BCV75_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCV75_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCV75_RS00025	COG0187	DNA topoisomerase II activity
BCV75_RS00035	COG0501	Belongs to the peptidase M48B family
BCV75_RS00075	COG0408	coproporphyrinogen oxidase activity
BCV75_RS00100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCV75_RS00115	COG4969	Belongs to the N-Me-Phe pilin family
BCV75_RS00145	COG0284	orotidine-5'-phosphate decarboxylase activity
BCV75_RS00180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BCV75_RS00190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCV75_RS00200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCV75_RS00205	COG0511	ligase activity, forming carbon-carbon bonds
BCV75_RS00210	COG0439	Biotin carboxylase
BCV75_RS00215	COG0210	DNA helicase
BCV75_RS00225	COG1017	nitric oxide dioxygenase activity
BCV75_RS00225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCV75_RS00235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCV75_RS00245	COG1040	competence protein
BCV75_RS00250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCV75_RS00255	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCV75_RS00265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BCV75_RS00300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCV75_RS00310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCV75_RS00340	COG3121	Chaperone
BCV75_RS00345	COG3539	Fimbrial protein
BCV75_RS00350	COG1546	Belongs to the CinA family
BCV75_RS00355	COG0477	Major facilitator Superfamily
BCV75_RS00360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCV75_RS00365	COG1923	regulation of RNA biosynthetic process
BCV75_RS00370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCV75_RS00375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCV75_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCV75_RS00395	COG1534	Rna-binding protein
BCV75_RS00425	COG1560	Kdo2-lipid A biosynthetic process
BCV75_RS00440	COG0228	four-way junction DNA binding
BCV75_RS00445	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCV75_RS00450	COG0336	Belongs to the RNA methyltransferase TrmD family
BCV75_RS00455	COG0335	large ribosomal subunit rRNA binding
BCV75_RS00475	COG2171	N-acyltransferase activity
BCV75_RS00480	COG1393	Belongs to the ArsC family
BCV75_RS00485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCV75_RS00490	COG0367	asparagine synthase
BCV75_RS00500	COG2070	2-Nitropropane dioxygenase
BCV75_RS00510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCV75_RS00515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCV75_RS00530	COG0339	signal peptide processing
BCV75_RS00560	COG0525	valine-tRNA ligase activity
BCV75_RS00600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV75_RS00610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCV75_RS00620	COG4221	oxidoreductase activity
BCV75_RS00640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCV75_RS00650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV75_RS00660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCV75_RS00705	COG2223	nitrite transmembrane transporter activity
BCV75_RS00710	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BCV75_RS00715	COG0739	heme binding
BCV75_RS00720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCV75_RS00750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCV75_RS00770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCV75_RS00775	COG1272	protein, Hemolysin III
BCV75_RS00780	COG0463	Glycosyl transferase, family 2
BCV75_RS00785	COG0084	hydrolase, TatD family'
BCV75_RS00800	COG0509	glycine decarboxylation via glycine cleavage system
BCV75_RS00805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCV75_RS00820	COG3956	TIGRFAM MazG family protein
BCV75_RS00825	COG1218	3'(2'),5'-bisphosphate nucleotidase
BCV75_RS00830	COG0494	nUDIX hydrolase
BCV75_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCV75_RS00850	COG0513	Belongs to the DEAD box helicase family
BCV75_RS00855	COG0720	synthase
BCV75_RS00885	COG1981	membrane
BCV75_RS00890	COG0825	malonyl-CoA metabolic process
BCV75_RS00895	COG0587	DNA-directed DNA polymerase activity
BCV75_RS00925	COG0512	Glutamine amidotransferase of anthranilate synthase
BCV75_RS00930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCV75_RS00935	COG0134	indole-3-glycerol-phosphate synthase activity
BCV75_RS00960	COG0006	proline dipeptidase activity
BCV75_RS00975	COG0343	queuine tRNA-ribosyltransferase activity
BCV75_RS00980	COG1862	Preprotein translocase
BCV75_RS00985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCV75_RS01000	COG0617	tRNA 3'-terminal CCA addition
BCV75_RS01010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCV75_RS01015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCV75_RS01020	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCV75_RS01025	COG0166	Belongs to the GPI family
BCV75_RS01040	COG0779	Required for maturation of 30S ribosomal subunits
BCV75_RS01045	COG0195	Participates in both transcription termination and antitermination
BCV75_RS01050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCV75_RS01055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCV75_RS01060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCV75_RS01070	COG1185	polyribonucleotide nucleotidyltransferase activity
BCV75_RS01075	COG1733	regulation of RNA biosynthetic process
BCV75_RS01080	COG0702	epimerase
BCV75_RS01140	COG2086	electron transfer activity
BCV75_RS01170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV75_RS01210	COG0477	Major facilitator Superfamily
BCV75_RS01225	COG0563	adenylate kinase activity
BCV75_RS01230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV75_RS01235	COG0671	phosphoesterase, PA-phosphatase related
BCV75_RS01245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCV75_RS01250	COG0628	permease
BCV75_RS01270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV75_RS01275	COG1090	epimerase
BCV75_RS01280	COG0318	PFAM AMP-dependent synthetase and ligase
BCV75_RS01315	COG1049	propionate catabolic process, 2-methylcitrate cycle
BCV75_RS01390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV75_RS01400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCV75_RS01410	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BCV75_RS01415	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BCV75_RS01420	COG1034	ATP synthesis coupled electron transport
BCV75_RS01440	COG0713	ATP synthesis coupled electron transport
BCV75_RS01455	COG1007	ATP synthesis coupled electron transport
BCV75_RS01460	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_RS01465	COG2851	Citrate transporter
BCV75_RS01480	COG0642	Histidine kinase
BCV75_RS01530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCV75_RS01535	COG4206	TonB-dependent receptor
BCV75_RS01540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BCV75_RS01560	COG0277	FAD linked oxidase domain protein
BCV75_RS01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV75_RS01575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCV75_RS01580	COG2124	cytochrome p450
BCV75_RS01590	COG0305	Participates in initiation and elongation during chromosome replication
BCV75_RS01605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV75_RS01610	COG0667	Aldo Keto reductase
BCV75_RS01615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCV75_RS01650	COG2194	sulfuric ester hydrolase activity
BCV75_RS01660	COG0352	thiamine-phosphate diphosphorylase activity
BCV75_RS01730	COG0494	nUDIX hydrolase
BCV75_RS01740	COG2193	ferroxidase activity
BCV75_RS01795	COG0861	Integral membrane protein TerC family
BCV75_RS01800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV75_RS01805	COG0531	amino acid
BCV75_RS01815	COG1116	anion transmembrane transporter activity
BCV75_RS01820	COG1322	Protein conserved in bacteria
BCV75_RS01830	COG2853	Lipoprotein
BCV75_RS01845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV75_RS01850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV75_RS01865	COG1074	ATP-dependent DNA helicase activity
BCV75_RS01890	COG0358	DNA primase activity
BCV75_RS01900	COG1610	YqeY-like protein
BCV75_RS01910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCV75_RS01915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCV75_RS01920	COG0668	transmembrane transport
BCV75_RS01940	COG1183	phosphatidylcholine synthase activity
BCV75_RS01950	COG0442	prolyl-tRNA aminoacylation
BCV75_RS01970	COG0604	alcohol dehydrogenase
BCV75_RS01975	COG0330	HflC and HflK could
BCV75_RS01980	COG0330	HflC and HflK could
BCV75_RS01995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCV75_RS02000	COG0105	UTP biosynthetic process
BCV75_RS02005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCV75_RS02025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_RS02030	COG1160	GTP binding
BCV75_RS02035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCV75_RS02050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BCV75_RS02055	COG1611	Belongs to the LOG family
BCV75_RS02060	COG4968	Prepilin-type N-terminal cleavage methylation domain
BCV75_RS02155	COG2878	Part of a membrane complex involved in electron transport
BCV75_RS02170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCV75_RS02175	COG3107	peptidoglycan biosynthetic process
BCV75_RS02185	COG1162	GTPase activity
BCV75_RS02190	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BCV75_RS02205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV75_RS02205	COG0519	Catalyzes the synthesis of GMP from XMP
BCV75_RS02235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCV75_RS02250	COG0037	tRNA processing
BCV75_RS02260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV75_RS02275	COG3590	peptidase
BCV75_RS02300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCV75_RS02310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCV75_RS02330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCV75_RS02335	COG3178	'Phosphotransferase
BCV75_RS02340	COG1555	photosystem II stabilization
BCV75_RS02345	COG1477	protein flavinylation
BCV75_RS02370	COG4774	siderophore transport
BCV75_RS02390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCV75_RS02405	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BCV75_RS02410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV75_RS02415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV75_RS02440	COG0459	protein refolding
BCV75_RS02450	COG1324	tolerance protein
BCV75_RS02460	COG0352	thiamine-phosphate diphosphorylase activity
BCV75_RS02460	COG0351	phosphomethylpyrimidine kinase
BCV75_RS02470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCV75_RS02525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCV75_RS02540	COG2311	Membrane
BCV75_RS02550	COG0791	NLP P60 protein
BCV75_RS02555	COG0791	NLP P60 protein
BCV75_RS02565	COG1301	dicarboxylic acid transport
BCV75_RS02575	COG0037	tRNA processing
BCV75_RS02580	COG1722	exodeoxyribonuclease VII activity
BCV75_RS02585	COG0142	geranyltranstransferase activity
BCV75_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_RS02640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCV75_RS02645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCV75_RS02670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BCV75_RS02675	COG0483	inositol monophosphate 1-phosphatase activity
BCV75_RS02685	COG1509	lysine 2,3-aminomutase activity
BCV75_RS02695	COG0402	S-adenosylhomocysteine deaminase activity
BCV75_RS02705	COG0546	phosphoglycolate phosphatase activity
BCV75_RS02720	COG5434	Belongs to the glycosyl hydrolase 28 family
BCV75_RS02725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV75_RS02745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV75_RS02750	COG1138	Cytochrome C-type biogenesis protein
BCV75_RS02755	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BCV75_RS02775	COG4133	protoheme IX ABC transporter activity
BCV75_RS02780	COG0436	Aminotransferase
BCV75_RS02795	COG1187	pseudouridine synthase activity
BCV75_RS02800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCV75_RS02805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BCV75_RS02830	COG1175	transmembrane transport
BCV75_RS02835	COG0395	ABC-type sugar transport system, permease component
BCV75_RS02870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCV75_RS02880	COG0776	regulation of translation
BCV75_RS02890	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BCV75_RS02905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCV75_RS02910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCV75_RS02920	COG0519	Catalyzes the synthesis of GMP from XMP
BCV75_RS02920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCV75_RS02940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCV75_RS02945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCV75_RS02950	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCV75_RS02955	COG0268	Binds directly to 16S ribosomal RNA
BCV75_RS02960	COG0728	peptidoglycan biosynthetic process
BCV75_RS02965	COG0196	riboflavin kinase activity
BCV75_RS02970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCV75_RS03090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV75_RS03105	COG3757	hydrolase, family 25
BCV75_RS03105	COG3409	Peptidoglycan-binding domain 1 protein
BCV75_RS03115	COG1064	alcohol dehydrogenase
BCV75_RS03130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV75_RS03135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV75_RS03140	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV75_RS03140	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCV75_RS03160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCV75_RS03165	COG0066	3-isopropylmalate dehydratase activity
BCV75_RS03170	COG0473	3-isopropylmalate dehydrogenase activity
BCV75_RS03200	COG0438	transferase activity, transferring glycosyl groups
BCV75_RS03215	COG0438	transferase activity, transferring glycosyl groups
BCV75_RS03220	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BCV75_RS03225	COG0745	RESPONSE REGULATOR receiver
BCV75_RS03235	COG2954	triphosphatase activity
BCV75_RS03245	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCV75_RS03255	COG1278	Cold shock
BCV75_RS03275	COG2914	Belongs to the UPF0125 (RnfH) family
BCV75_RS03280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_RS03290	COG0497	DNA recombination
BCV75_RS03300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCV75_RS03310	COG0484	heat shock protein binding
BCV75_RS03315	COG1605	Chorismate mutase
BCV75_RS03315	COG0287	Prephenate dehydrogenase
BCV75_RS03335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCV75_RS03360	COG4555	ABC transporter
BCV75_RS03365	COG1668	transmembrane transport
BCV75_RS03375	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCV75_RS03380	COG1605	Chorismate mutase
BCV75_RS03380	COG0077	Prephenate dehydratase
BCV75_RS03385	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCV75_RS03440	COG0322	excinuclease ABC activity
BCV75_RS03445	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCV75_RS03475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCV75_RS03480	COG0489	protein tyrosine kinase activity
BCV75_RS03485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BCV75_RS03490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCV75_RS03545	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCV75_RS03555	COG1192	Involved in chromosome partitioning
BCV75_RS03560	COG1475	DNA binding
BCV75_RS03570	COG0463	Glycosyl transferase, family 2
BCV75_RS03580	COG0318	PFAM AMP-dependent synthetase and ligase
BCV75_RS03590	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BCV75_RS03605	COG0676	glucose-6-phosphate 1-epimerase activity
BCV75_RS03615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCV75_RS03620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCV75_RS03635	COG1297	OPT oligopeptide transporter protein
BCV75_RS03645	COG0823	Involved in the tonB-independent uptake of proteins
BCV75_RS03645	COG1506	peptidase
BCV75_RS03650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_RS03665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCV75_RS03680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCV75_RS03685	COG1381	Involved in DNA repair and RecF pathway recombination
BCV75_RS03690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCV75_RS03695	COG0571	ribonuclease III activity
BCV75_RS03715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCV75_RS03740	COG4953	penicillin-binding protein 1C
BCV75_RS03755	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BCV75_RS03765	COG1686	Belongs to the peptidase S11 family
BCV75_RS03775	COG1678	Uncharacterized ACR, COG1678
BCV75_RS03785	COG0540	Belongs to the ATCase OTCase family
BCV75_RS03790	COG0460	homoserine dehydrogenase
BCV75_RS03790	COG0527	aspartate kinase activity
BCV75_RS03795	COG0083	homoserine kinase activity
BCV75_RS03805	COG0124	histidyl-tRNA synthetase
BCV75_RS03815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCV75_RS03820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCV75_RS03830	COG0131	Imidazoleglycerol-phosphate dehydratase
BCV75_RS03830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCV75_RS03840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCV75_RS03855	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BCV75_RS03860	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCV75_RS03865	COG0235	Class ii aldolase
BCV75_RS03870	COG0531	amino acid
BCV75_RS03875	COG0531	amino acid
BCV75_RS03880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCV75_RS03885	COG0277	FAD linked oxidase domain protein
BCV75_RS03890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCV75_RS03990	COG2951	lytic endotransglycosylase activity
BCV75_RS04020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCV75_RS04035	COG0495	leucyl-tRNA aminoacylation
BCV75_RS04045	COG3118	belongs to the thioredoxin family
BCV75_RS04055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCV75_RS04070	COG2183	response to ionizing radiation
BCV75_RS04085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV75_RS04095	COG0328	RNA-DNA hybrid ribonuclease activity
BCV75_RS04100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV75_RS04105	COG0631	protein serine/threonine phosphatase activity
BCV75_RS04120	COG0859	PFAM glycosyl transferase family 9
BCV75_RS04140	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCV75_RS04145	COG2967	ApaG domain
BCV75_RS04150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCV75_RS04155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCV75_RS04160	COG0704	Plays a role in the regulation of phosphate uptake
BCV75_RS04165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCV75_RS04170	COG0581	inorganic phosphate transmembrane transporter activity
BCV75_RS04175	COG0573	inorganic phosphate transmembrane transporter activity
BCV75_RS04180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCV75_RS04185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCV75_RS04185	COG4651	solute:proton antiporter activity
BCV75_RS04200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCV75_RS04210	COG0488	(ABC) transporter
BCV75_RS04370	COG0445	tRNA wobble uridine modification
BCV75_RS04410	COG1469	GTP cyclohydrolase I activity
BCV75_RS04425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCV75_RS04435	COG2902	Dehydrogenase
BCV75_RS04440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCV75_RS04480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCV75_RS04485	COG4221	oxidoreductase activity
BCV75_RS04490	COG3077	Addiction module antitoxin, RelB DinJ family
BCV75_RS04495	COG3041	Addiction module toxin RelE StbE family
BCV75_RS04565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV75_RS04590	COG2925	Exonuclease
BCV75_RS04605	COG0025	NhaP-type Na H and K H
BCV75_RS04615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BCV75_RS04625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCV75_RS04650	COG0006	proline dipeptidase activity
BCV75_RS04695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCV75_RS04700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BCV75_RS04735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCV75_RS04740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCV75_RS04750	COG0557	exoribonuclease II activity
BCV75_RS04760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCV75_RS04765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCV75_RS04770	COG0302	gtp cyclohydrolase
BCV75_RS04780	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BCV75_RS04785	COG1289	transmembrane transporter activity
BCV75_RS04795	COG0151	Belongs to the GarS family
BCV75_RS04800	COG0138	bifunctional purine biosynthesis protein purh
BCV75_RS04815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCV75_RS04825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV75_RS04845	COG0596	Alpha beta hydrolase
BCV75_RS04850	COG0727	PFAM Uncharacterised protein family (UPF0153)
BCV75_RS04860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCV75_RS04860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCV75_RS04885	COG0189	ligase activity
BCV75_RS04900	COG0840	transmembrane signaling receptor activity
BCV75_RS04905	COG2198	Histidine kinase
BCV75_RS04905	COG0784	Response regulator, receiver
BCV75_RS04905	COG0643	Histidine kinase
BCV75_RS04935	COG0285	dihydrofolate synthase activity
BCV75_RS04970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV75_RS04975	COG1301	dicarboxylic acid transport
BCV75_RS04980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCV75_RS04985	COG0357	Ribosomal RNA small subunit methyltransferase G
BCV75_RS04990	COG2091	lysine biosynthetic process via aminoadipic acid
BCV75_RS05065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCV75_RS05075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV75_RS05115	COG0084	hydrolase, TatD family'
BCV75_RS05130	COG0552	protein localization to endoplasmic reticulum
BCV75_RS05140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BCV75_RS05150	COG0217	transcriptional regulatory protein
BCV75_RS05155	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCV75_RS05160	COG0632	four-way junction helicase activity
BCV75_RS05165	COG3158	transport of potassium into the cell
BCV75_RS05170	COG2255	four-way junction helicase activity
BCV75_RS05175	COG0824	Thioesterase
BCV75_RS05195	COG0823	Involved in the tonB-independent uptake of proteins
BCV75_RS05200	COG2885	chlorophyll binding
BCV75_RS05210	COG0602	queuosine metabolic process
BCV75_RS05215	COG0588	phosphoglycerate mutase activity
BCV75_RS05220	COG1515	deoxyribonuclease V activity
BCV75_RS05240	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCV75_RS05250	COG0406	alpha-ribazole phosphatase activity
BCV75_RS05640	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCV75_RS05665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCV75_RS05670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCV75_RS05710	COG0675	Transposase, IS605 OrfB family
BCV75_RS05805	COG3772	lysozyme
BCV75_RS05925	COG3617	BRO family, N-terminal domain
BCV75_RS05955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCV75_RS05960	COG3852	Histidine kinase
BCV75_RS05965	COG2204	response regulator
BCV75_RS05980	COG0004	ammonium transporteR
BCV75_RS05985	COG0347	Belongs to the P(II) protein family
BCV75_RS05990	COG0174	glutamine synthetase
BCV75_RS05995	COG1968	undecaprenyl-diphosphatase activity
BCV75_RS06000	COG2353	YceI-like domain
BCV75_RS06020	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCV75_RS06055	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BCV75_RS06060	COG1764	response to oxidative stress
BCV75_RS06065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCV75_RS06075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCV75_RS06095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCV75_RS06100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCV75_RS06105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCV75_RS06110	COG1399	metal-binding, possibly nucleic acid-binding protein
BCV75_RS06120	COG0714	Associated with various cellular activities
BCV75_RS06140	COG0537	adenosine 5'-monophosphoramidase activity
BCV75_RS06150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCV75_RS06170	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BCV75_RS06190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCV75_RS06220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCV75_RS06260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCV75_RS06265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCV75_RS06270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCV75_RS06275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCV75_RS06290	COG0251	oxidation-reduction process
BCV75_RS06330	COG3657	addiction module killer protein
BCV75_RS06335	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_RS06430	COG2369	cell adhesion
BCV75_RS06475	COG3772	lysozyme
BCV75_RS06500	COG0305	Participates in initiation and elongation during chromosome replication
BCV75_RS06525	COG3617	BRO family, N-terminal domain
BCV75_RS06530	COG3617	BRO family, N-terminal domain
BCV75_RS06645	COG0629	single-stranded DNA binding
BCV75_RS06655	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BCV75_RS06660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCV75_RS06660	COG0392	lysyltransferase activity
BCV75_RS06675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCV75_RS06685	COG0463	Glycosyl transferase, family 2
BCV75_RS06740	COG3275	phosphorelay sensor kinase activity
BCV75_RS06750	COG2943	transferase activity, transferring hexosyl groups
BCV75_RS06765	COG2226	methyltransferase
BCV75_RS06780	COG2027	D-alanyl-D-alanine carboxypeptidase
BCV75_RS06790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCV75_RS06805	COG2900	Belongs to the SlyX family
BCV75_RS06820	COG0386	Belongs to the glutathione peroxidase family
BCV75_RS06830	COG1131	(ABC) transporter
BCV75_RS06850	COG3657	addiction module killer protein
BCV75_RS06855	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_RS06910	COG3657	addiction module killer protein
BCV75_RS06915	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_RS07010	COG2369	cell adhesion
BCV75_RS07025	COG3567	Phage-associated protein, HI1409 family
BCV75_RS07030	COG5410	chromosome segregation
BCV75_RS07055	COG3772	lysozyme
BCV75_RS07105	COG0114	fumarate hydratase activity
BCV75_RS07115	COG2850	peptidyl-arginine hydroxylation
BCV75_RS07120	COG0567	Dehydrogenase, E1 component
BCV75_RS07145	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCV75_RS07165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BCV75_RS07170	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCV75_RS07195	COG0583	DNA-binding transcription factor activity
BCV75_RS07200	COG3634	alkyl hydroperoxide reductase activity
BCV75_RS07220	COG1450	Type ii and iii secretion system protein
BCV75_RS07235	COG3166	PFAM Fimbrial assembly family protein
BCV75_RS07240	COG3156	type II secretion system protein K
BCV75_RS07245	COG4795	General secretion pathway protein
BCV75_RS07250	COG2165	general secretion pathway protein
BCV75_RS07255	COG4970	Tfp pilus assembly protein FimT
BCV75_RS07260	COG2165	general secretion pathway protein
BCV75_RS07265	COG1459	type II secretion system
BCV75_RS07270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCV75_RS07275	COG5295	Hep Hag repeat protein
BCV75_RS07295	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV75_RS07300	COG0596	Alpha beta hydrolase
BCV75_RS07330	COG1561	YicC-like family, N-terminal region
BCV75_RS07335	COG0194	GDP metabolic process
BCV75_RS07340	COG1758	RNA polymerase activity
BCV75_RS07345	COG2895	sulfate adenylyltransferase (ATP) activity
BCV75_RS07345	COG0529	Catalyzes the synthesis of activated sulfate
BCV75_RS07355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCV75_RS07365	COG0175	sulfate reduction
BCV75_RS07380	COG2912	Transglutaminase-like superfamily
BCV75_RS07400	COG0308	aminopeptidase N
BCV75_RS07405	COG2226	methyltransferase
BCV75_RS07415	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BCV75_RS07435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCV75_RS07455	COG1959	2 iron, 2 sulfur cluster binding
BCV75_RS07460	COG0719	Fe-S assembly protein
BCV75_RS07465	COG0396	ATPase activity
BCV75_RS07470	COG0719	Fe-S assembly protein
BCV75_RS07475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCV75_RS07490	COG0297	glycogen (starch) synthase activity
BCV75_RS07495	COG0726	polysaccharide deacetylase
BCV75_RS07500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCV75_RS07505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCV75_RS07510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCV75_RS07515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCV75_RS07520	COG1609	Transcriptional regulator
BCV75_RS07535	COG0837	glucose binding
BCV75_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_RS07555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCV75_RS07560	COG4191	Histidine kinase
BCV75_RS07565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCV75_RS07570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCV75_RS07575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCV75_RS07585	COG1674	ftsk spoiiie
BCV75_RS07590	COG0492	ferredoxin-NADP+ reductase activity
BCV75_RS07600	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BCV75_RS07605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCV75_RS07615	COG0542	response to heat
BCV75_RS07620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BCV75_RS07635	COG2915	High frequency lysogenization protein hflD homolog
BCV75_RS07645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV75_RS07665	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCV75_RS07680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCV75_RS07685	COG4974	Belongs to the 'phage' integrase family
BCV75_RS07690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCV75_RS07730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCV75_RS07735	COG0271	Belongs to the BolA IbaG family
BCV75_RS07745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BCV75_RS07760	COG1137	ATPase activity
BCV75_RS07780	COG1660	Displays ATPase and GTPase activities
BCV75_RS07795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCV75_RS07815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCV75_RS07820	COG0629	single-stranded DNA binding
BCV75_RS07825	COG0142	geranyltranstransferase activity
BCV75_RS07830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCV75_RS07835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCV75_RS07840	COG1845	cytochrome c oxidase, subunit III
BCV75_RS07845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCV75_RS07850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV75_RS07850	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCV75_RS07870	COG0783	Belongs to the Dps family
BCV75_RS07875	COG0514	ATP-dependent DNA helicase (RecQ)
BCV75_RS07885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCV75_RS07895	COG0159	tryptophan synthase activity
BCV75_RS07900	COG0133	tryptophan synthase activity
BCV75_RS07905	COG0135	phosphoribosylanthranilate isomerase activity
BCV75_RS07920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCV75_RS07930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCV75_RS07935	COG2890	protein-(glutamine-N5) methyltransferase activity
BCV75_RS07940	COG1999	signal sequence binding
BCV75_RS07960	COG0741	lytic transglycosylase activity
BCV75_RS07965	COG0617	tRNA 3'-terminal CCA addition
BCV75_RS07970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCV75_RS07985	COG0156	8-amino-7-oxononanoate synthase activity
BCV75_RS07990	COG2267	carboxylic ester hydrolase activity
BCV75_RS08000	COG1846	Transcriptional regulator
BCV75_RS08010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCV75_RS08020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCV75_RS08025	COG4208	sulfate ABC transporter
BCV75_RS08030	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCV75_RS08045	COG3142	Participates in the control of copper homeostasis
BCV75_RS08055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV75_RS08060	COG0259	pyridoxamine-phosphate oxidase activity
BCV75_RS08070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCV75_RS08075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCV75_RS08085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCV75_RS08100	COG2353	YceI-like domain
BCV75_RS08115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCV75_RS08140	COG2894	cell division
BCV75_RS08160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCV75_RS08165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCV75_RS08175	COG0768	penicillin binding
BCV75_RS08180	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCV75_RS08185	COG1792	Involved in formation and maintenance of cell shape
BCV75_RS08190	COG1077	Cell shape determining protein MreB Mrl
BCV75_RS08235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BCV75_RS08240	COG1127	ABC transporter
BCV75_RS08245	COG3218	ABC-type transport auxiliary lipoprotein component
BCV75_RS08245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BCV75_RS08260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BCV75_RS08260	COG0644	oxidoreductase
BCV75_RS08270	COG2840	Smr protein MutS2
BCV75_RS08275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCV75_RS08280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCV75_RS08285	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BCV75_RS08290	COG0148	phosphopyruvate hydratase activity
BCV75_RS08295	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCV75_RS08325	COG1253	flavin adenine dinucleotide binding
BCV75_RS08330	COG2733	membrane
BCV75_RS08355	COG0321	lipoyl(octanoyl) transferase activity
BCV75_RS08360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCV75_RS08395	COG0668	transmembrane transport
BCV75_RS08400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BCV75_RS08420	COG2373	Large extracellular alpha-helical protein
BCV75_RS08580	COG0582	viral genome integration into host DNA
BCV75_RS08595	COG0729	surface antigen
BCV75_RS08600	COG1956	GAF domain-containing protein
BCV75_RS08605	COG1643	Atp-dependent helicase
BCV75_RS08630	COG1131	(ABC) transporter
BCV75_RS08635	COG0842	Transport permease protein
BCV75_RS08680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCV75_RS08685	COG0039	L-malate dehydrogenase activity
BCV75_RS08690	COG0625	glutathione transferase activity
BCV75_RS08695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV75_RS08735	COG1187	pseudouridine synthase activity
BCV75_RS08750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV75_RS08755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCV75_RS08800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCV75_RS08810	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCV75_RS08825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCV75_RS08845	COG0606	chelatase, subunit chli
BCV75_RS08850	COG2960	long-chain fatty acid transporting porin activity
BCV75_RS08855	COG0203	ribosomal protein L17
BCV75_RS08865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCV75_RS08870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCV75_RS08875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCV75_RS08880	COG0201	protein transport
BCV75_RS08885	COG0200	Binds to the 23S rRNA
BCV75_RS08890	COG1841	ribosomal large subunit assembly
BCV75_RS08895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCV75_RS08905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCV75_RS08910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCV75_RS08915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCV75_RS08920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCV75_RS08925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCV75_RS08935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCV75_RS08940	COG0255	Belongs to the universal ribosomal protein uL29 family
BCV75_RS08950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCV75_RS08955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCV75_RS08960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCV75_RS08965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCV75_RS08975	COG0088	Forms part of the polypeptide exit tunnel
BCV75_RS08980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCV75_RS08995	COG0356	it plays a direct role in the translocation of protons across the membrane
BCV75_RS09005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCV75_RS09010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCV75_RS09015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCV75_RS09020	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCV75_RS09025	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCV75_RS09030	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCV75_RS09040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCV75_RS09055	COG1064	alcohol dehydrogenase
BCV75_RS09070	COG0583	DNA-binding transcription factor activity
BCV75_RS09075	COG0312	modulator of DNA gyrase
BCV75_RS09080	COG3028	Belongs to the UPF0307 family
BCV75_RS09085	COG0312	modulator of DNA gyrase
BCV75_RS09100	COG0424	maF-like protein
BCV75_RS09115	COG0494	nUDIX hydrolase
BCV75_RS09125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCV75_RS09135	COG0019	diaminopimelate decarboxylase activity
BCV75_RS09140	COG1024	Enoyl-CoA hydratase
BCV75_RS09155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCV75_RS09165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCV75_RS09175	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCV75_RS09185	COG0505	Belongs to the CarA family
BCV75_RS09190	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCV75_RS09250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCV75_RS09270	COG1663	tetraacyldisaccharide 4'-kinase activity
BCV75_RS09275	COG1132	(ABC) transporter
BCV75_RS09285	COG0811	peptide transport
BCV75_RS09295	COG1136	(ABC) transporter
BCV75_RS09300	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCV75_RS09315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCV75_RS09325	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BCV75_RS09330	COG2009	succinate dehydrogenase
BCV75_RS09340	COG0354	folic acid binding
BCV75_RS09345	COG3842	ATPase activity
BCV75_RS09350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCV75_RS09355	COG0837	glucose binding
BCV75_RS09360	COG0363	glucosamine-6-phosphate deaminase activity
BCV75_RS09425	COG0233	cytoplasmic translational termination
BCV75_RS09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCV75_RS09435	COG0575	Belongs to the CDS family
BCV75_RS09460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV75_RS09465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_RS09470	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_RS09475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCV75_RS09485	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCV75_RS09505	COG2937	Belongs to the GPAT DAPAT family
BCV75_RS09535	COG1946	Acyl-CoA thioesterase
BCV75_RS09545	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BCV75_RS09555	COG1914	H( )-stimulated, divalent metal cation uptake system
BCV75_RS09600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCV75_RS09615	COG0165	Argininosuccinate lyase
BCV75_RS09625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCV75_RS09635	COG0137	argininosuccinate synthase activity
BCV75_RS09640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCV75_RS09655	COG0215	cysteine-tRNA ligase activity
BCV75_RS09660	COG2166	iron-sulfur cluster assembly
BCV75_RS09680	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCV75_RS09685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCV75_RS09705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BCV75_RS09715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCV75_RS09720	COG0742	ribosomal rna small subunit methyltransferase
BCV75_RS09725	COG0326	Molecular chaperone. Has ATPase activity
BCV75_RS09730	COG0281	malic enzyme
BCV75_RS09730	COG0280	phosphate acetyltransferase
BCV75_RS09735	COG1301	dicarboxylic acid transport
BCV75_RS09750	COG0784	Response regulator, receiver
BCV75_RS09750	COG2205	protein histidine kinase activity
BCV75_RS09785	COG0556	nucleotide-excision repair
BCV75_RS09810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCV75_RS09835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCV75_RS09840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCV75_RS09860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV75_RS09860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCV75_RS09880	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCV75_RS09885	COG0488	(ABC) transporter
BCV75_RS09895	COG3011	Protein conserved in bacteria
BCV75_RS09905	COG0564	pseudouridine synthase activity
BCV75_RS09910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCV75_RS09920	COG1918	ferrous iron import across plasma membrane
BCV75_RS09920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCV75_RS09935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCV75_RS09945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCV75_RS09960	COG0758	DNA mediated transformation
BCV75_RS09965	COG2922	Belongs to the Smg family
BCV75_RS09975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCV75_RS09975	COG1754	DNA topoisomerase type I activity
BCV75_RS09980	COG0009	L-threonylcarbamoyladenylate synthase
BCV75_RS10010	COG2969	positive regulation of protein catabolic process
BCV75_RS10015	COG0625	glutathione transferase activity
BCV75_RS10020	COG2857	Cytochrome c1
BCV75_RS10025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCV75_RS10045	COG1702	phosphate starvation-inducible protein PhoH
BCV75_RS10050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCV75_RS10060	COG4535	Mg2 and Co2 transporter CorC
BCV75_RS10140	COG1199	ATP-dependent helicase activity
BCV75_RS10150	COG0288	reversible hydration of carbon dioxide
BCV75_RS10175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCV75_RS10200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCV75_RS10205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCV75_RS10220	COG0626	cystathionine gamma-synthase activity
BCV75_RS10225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCV75_RS10230	COG0739	heme binding
BCV75_RS10245	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BCV75_RS10250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCV75_RS10255	COG1238	metal cluster binding
BCV75_RS10270	COG5002	protein histidine kinase activity
BCV75_RS10280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCV75_RS10285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCV75_RS10290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCV75_RS10295	COG1388	LysM domain
BCV75_RS10295	COG3858	chitin binding
BCV75_RS10300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BCV75_RS10310	COG1472	Belongs to the glycosyl hydrolase 3 family
BCV75_RS10325	COG3537	Alpha-1,2-mannosidase
BCV75_RS10335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCV75_RS10340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCV75_RS10345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BCV75_RS10355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV75_RS10360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCV75_RS10400	COG3588	fructose-bisphosphate aldolase
BCV75_RS10410	COG0469	pyruvate kinase activity
BCV75_RS10420	COG0126	phosphoglycerate kinase activity
BCV75_RS10425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCV75_RS10430	COG0735	belongs to the Fur family
BCV75_RS10440	COG5297	Belongs to the glycosyl hydrolase family 6
BCV75_RS10440	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCV75_RS10450	COG0612	Peptidase, M16
BCV75_RS10465	COG4305	rare lipoprotein A
BCV75_RS10470	COG0653	protein targeting
BCV75_RS10475	COG0739	heme binding
BCV75_RS10485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BCV75_RS10495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCV75_RS10505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCV75_RS10510	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCV75_RS10515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCV75_RS10520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCV75_RS10535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCV75_RS10540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCV75_RS10550	COG3116	cell division
BCV75_RS10555	COG0275	rRNA processing
BCV75_RS10575	COG0471	metal ion transport
BCV75_RS10575	COG3273	potassium ion transport
BCV75_RS10580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCV75_RS10615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BCV75_RS10615	COG2755	lipolytic protein G-D-S-L family
BCV75_RS10645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCV75_RS10675	COG0640	Transcriptional regulator
BCV75_RS10680	COG2391	methyltransferase activity
BCV75_RS10685	COG2391	methyltransferase activity
BCV75_RS10690	COG0730	response to heat
BCV75_RS10695	COG0717	Belongs to the dCTP deaminase family
BCV75_RS10705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCV75_RS10710	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCV75_RS10715	COG0802	atpase or kinase
BCV75_RS10755	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BCV75_RS10775	COG0776	regulation of translation
BCV75_RS10780	COG0072	phenylalanine-tRNA ligase activity
BCV75_RS10780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCV75_RS10785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCV75_RS10790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCV75_RS10800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCV75_RS10805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCV75_RS10830	COG0745	RESPONSE REGULATOR receiver
BCV75_RS10840	COG0237	dephospho-CoA kinase activity
BCV75_RS10845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCV75_RS10890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCV75_RS10900	COG2831	hemolysin activation secretion protein
BCV75_RS10925	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BCV75_RS10945	COG3115	cell septum assembly
BCV75_RS10955	COG0359	binds to the 23S rRNA
BCV75_RS10960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCV75_RS10970	COG0316	Belongs to the HesB IscA family
BCV75_RS10975	COG0017	Asparaginyl-tRNA synthetase
BCV75_RS11005	COG0167	dihydroorotate dehydrogenase activity
BCV75_RS11010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCV75_RS11015	COG0697	spore germination
BCV75_RS11020	COG0671	phosphoesterase, PA-phosphatase related
BCV75_RS11025	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCV75_RS11035	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BCV75_RS11040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCV75_RS11055	COG1132	(ABC) transporter
BCV75_RS11065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BCV75_RS11070	COG1538	Outer membrane efflux protein
BCV75_RS11075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCV75_RS11090	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCV75_RS11115	COG0473	3-isopropylmalate dehydrogenase activity
BCV75_RS11125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCV75_RS11135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BCV75_RS11145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCV75_RS11145	COG0316	Belongs to the HesB IscA family
BCV75_RS11150	COG2154	pterin-4-alpha-carbinolamine dehydratase
BCV75_RS11160	COG0564	pseudouridine synthase activity
BCV75_RS11170	COG2197	response regulator
BCV75_RS11175	COG1054	Belongs to the UPF0176 family
BCV75_RS11190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCV75_RS11205	COG0488	(ABC) transporter
BCV75_RS11215	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BCV75_RS11220	COG1278	Cold shock
BCV75_RS11230	COG0501	Belongs to the peptidase M48B family
BCV75_RS11240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV75_RS11245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCV75_RS11250	COG0049	tRNA binding
BCV75_RS11260	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCV75_RS11265	COG0085	RNA polymerase activity
BCV75_RS11270	COG0222	ribosome binding
BCV75_RS11275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCV75_RS11280	COG0081	regulation of translation
BCV75_RS11285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCV75_RS11290	COG0250	Participates in transcription elongation, termination and antitermination
BCV75_RS11295	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCV75_RS11305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCV75_RS11325	COG0012	GTP binding
BCV75_RS11330	COG0193	aminoacyl-tRNA hydrolase activity
BCV75_RS11350	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCV75_RS11355	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BCV75_RS11365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCV75_RS11370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCV75_RS11380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCV75_RS11380	COG0116	Belongs to the methyltransferase superfamily
BCV75_RS11430	COG2095	MarC family integral membrane protein
BCV75_RS11440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCV75_RS11455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCV75_RS11470	COG2132	Multicopper oxidase
BCV75_RS11480	COG0210	DNA helicase
BCV75_RS11485	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BCV75_RS11490	COG0616	signal peptide processing
BCV75_RS11515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCV75_RS11525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCV75_RS11530	COG2201	protein-glutamate methylesterase activity
BCV75_RS11535	COG2177	Part of the ABC transporter FtsEX involved in
BCV75_RS11540	COG2884	Cell division ATP-binding protein ftsE
BCV75_RS11545	COG0513	Belongs to the DEAD box helicase family
BCV75_RS11550	COG3118	belongs to the thioredoxin family
BCV75_RS11555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCV75_RS11570	COG0793	Belongs to the peptidase S41A family
BCV75_RS11575	COG4942	peptidase
BCV75_RS11590	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCV75_RS11595	COG0493	'glutamate synthase
BCV75_RS11600	COG0069	glutamate synthase activity
BCV75_RS11600	COG0070	glutamate synthase
BCV75_RS11600	COG0067	glutamate synthase
BCV75_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
BCV75_RS11660	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV75_RS11705	COG1280	lysine exporter protein (LysE YggA)
BCV75_RS11715	COG4942	peptidase
BCV75_RS11745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCV75_RS11760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCV75_RS11855	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCV75_RS11860	COG3657	addiction module killer protein
BCV75_RS11925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCV75_RS11935	COG0706	membrane insertase activity
BCV75_RS11940	COG0594	ribonuclease P activity
BCV75_RS11990	COG3657	addiction module killer protein
BCV75_RS12000	COG3609	addiction module antidote protein, CC2985 family
BCV75_RS12010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCV75_RS12105	COG0629	single-stranded DNA binding
BCV75_RS12115	COG4962	Type ii secretion system protein e
BCV75_RS12130	COG3451	type IV secretory pathway VirB4