locus-tag	class	description
PD_RS00010	COG0592	DNA-directed DNA polymerase activity
PD_RS00025	COG0187	DNA topoisomerase II activity
PD_RS00035	COG0501	Belongs to the peptidase M48B family
PD_RS00065	COG4946	Tricorn protease homolog
PD_RS00065	COG1506	peptidase
PD_RS00065	COG0823	Involved in the tonB-independent uptake of proteins
PD_RS00095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PD_RS00175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PD_RS00185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PD_RS00200	COG0511	ligase activity, forming carbon-carbon bonds
PD_RS00205	COG0439	Biotin carboxylase
PD_RS00210	COG0210	DNA helicase
PD_RS00240	COG1040	competence protein
PD_RS00250	COG1752	Esterase of the alpha-beta hydrolase superfamily
PD_RS00295	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PD_RS00305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PD_RS00340	COG3121	Chaperone
PD_RS00345	COG3539	Fimbrial protein
PD_RS00350	COG1546	Belongs to the CinA family
PD_RS00355	COG0477	Major facilitator Superfamily
PD_RS00360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PD_RS00375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PD_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PD_RS00395	COG1534	Rna-binding protein
PD_RS00430	COG1560	Kdo2-lipid A biosynthetic process
PD_RS00435	COG1519	Transferase
PD_RS00475	COG1393	Belongs to the ArsC family
PD_RS00485	COG0367	asparagine synthase
PD_RS00495	COG2070	2-Nitropropane dioxygenase
PD_RS00525	COG0339	signal peptide processing
PD_RS00540	COG2132	Multicopper oxidase
PD_RS00575	COG0795	lipopolysaccharide-transporting ATPase activity
PD_RS00610	COG4221	oxidoreductase activity
PD_RS00630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PD_RS00640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PD_RS00695	COG2223	nitrite transmembrane transporter activity
PD_RS00705	COG0739	heme binding
PD_RS00740	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PD_RS00755	COG1028	Short-chain dehydrogenase reductase Sdr
PD_RS00765	COG1272	protein, Hemolysin III
PD_RS00770	COG0463	Glycosyl transferase, family 2
PD_RS00775	COG0084	hydrolase, TatD family'
PD_RS00805	COG0330	HflC and HflK could
PD_RS00810	COG3956	TIGRFAM MazG family protein
PD_RS00815	COG1218	3'(2'),5'-bisphosphate nucleotidase
PD_RS00820	COG0494	nUDIX hydrolase
PD_RS00830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PD_RS00835	COG0513	Belongs to the DEAD box helicase family
PD_RS00840	COG0720	synthase
PD_RS00865	COG1981	membrane
PD_RS00900	COG0512	Glutamine amidotransferase of anthranilate synthase
PD_RS00935	COG0006	proline dipeptidase activity
PD_RS00955	COG1862	Preprotein translocase
PD_RS00960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PD_RS00965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PD_RS00975	COG0617	tRNA 3'-terminal CCA addition
PD_RS01015	COG0195	Participates in both transcription termination and antitermination
PD_RS01045	COG1733	regulation of RNA biosynthetic process
PD_RS01050	COG0702	epimerase
PD_RS01100	COG2086	electron transfer activity
PD_RS01130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PD_RS01160	COG0477	Major facilitator Superfamily
PD_RS01180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PD_RS01185	COG0671	phosphoesterase, PA-phosphatase related
PD_RS01195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PD_RS01200	COG0628	permease
PD_RS01220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PD_RS01225	COG1090	epimerase
PD_RS01230	COG0318	PFAM AMP-dependent synthetase and ligase
PD_RS01250	COG1049	propionate catabolic process, 2-methylcitrate cycle
PD_RS01270	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PD_RS01305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PD_RS01335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PD_RS01355	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
PD_RS01360	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PD_RS01365	COG1034	ATP synthesis coupled electron transport
PD_RS01400	COG1007	ATP synthesis coupled electron transport
PD_RS01405	COG1028	Short-chain dehydrogenase reductase Sdr
PD_RS01410	COG2851	Citrate transporter
PD_RS01425	COG0642	Histidine kinase
PD_RS01445	COG0784	Response regulator, receiver
PD_RS01445	COG2205	protein histidine kinase activity
PD_RS01460	COG0281	malic enzyme
PD_RS01460	COG0280	phosphate acetyltransferase
PD_RS01470	COG0742	ribosomal rna small subunit methyltransferase
PD_RS01485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PD_RS01505	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PD_RS01530	COG2166	iron-sulfur cluster assembly
PD_RS01560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PD_RS01635	COG1321	iron dependent repressor
PD_RS01655	COG1946	Acyl-CoA thioesterase
PD_RS01745	COG0575	Belongs to the CDS family
PD_RS01835	COG0354	folic acid binding
PD_RS01845	COG2009	succinate dehydrogenase
PD_RS01850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PD_RS01860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PD_RS01890	COG0811	peptide transport
PD_RS01940	COG3093	addiction module antidote protein HigA
PD_RS01950	COG2944	sequence-specific DNA binding
PD_RS02015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PD_RS02035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PD_RS02105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PD_RS02110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PD_RS02130	COG1024	Enoyl-CoA hydratase
PD_RS02135	COG0019	diaminopimelate decarboxylase activity
PD_RS02155	COG0494	nUDIX hydrolase
PD_RS02160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PD_RS02185	COG0312	modulator of DNA gyrase
PD_RS02195	COG0312	modulator of DNA gyrase
PD_RS02200	COG0583	DNA-binding transcription factor activity
PD_RS02215	COG1064	alcohol dehydrogenase
PD_RS02275	COG0356	it plays a direct role in the translocation of protons across the membrane
PD_RS02385	COG0201	protein transport
PD_RS02415	COG2960	long-chain fatty acid transporting porin activity
PD_RS02420	COG0606	chelatase, subunit chli
PD_RS02445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PD_RS02510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PD_RS02515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PD_RS02530	COG1187	pseudouridine synthase activity
PD_RS02535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PD_RS02555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PD_RS02560	COG0625	glutathione transferase activity
PD_RS02570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PD_RS02575	COG1217	gtp-binding protein TYPA
PD_RS02600	COG0842	Transport permease protein
PD_RS02605	COG1131	(ABC) transporter
PD_RS02625	COG1643	Atp-dependent helicase
PD_RS02635	COG1956	GAF domain-containing protein
PD_RS02640	COG0729	surface antigen
PD_RS02645	COG2911	Protein conserved in bacteria
PD_RS02730	COG0668	transmembrane transport
PD_RS02790	COG2733	membrane
PD_RS02795	COG1253	flavin adenine dinucleotide binding
PD_RS02860	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
PD_RS02860	COG0644	oxidoreductase
PD_RS02875	COG3218	ABC-type transport auxiliary lipoprotein component
PD_RS02875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PD_RS02880	COG1127	ABC transporter
PD_RS02885	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PD_RS02905	COG1077	Cell shape determining protein MreB Mrl
PD_RS02910	COG1792	Involved in formation and maintenance of cell shape
PD_RS02915	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PD_RS02920	COG0768	penicillin binding
PD_RS02925	COG0772	Belongs to the SEDS family
PD_RS02935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PD_RS02955	COG2894	cell division
PD_RS02980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PD_RS02995	COG2353	YceI-like domain
PD_RS03065	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PD_RS03070	COG4208	sulfate ABC transporter
PD_RS03095	COG1846	Transcriptional regulator
PD_RS03135	COG0741	lytic transglycosylase activity
PD_RS03145	COG1999	signal sequence binding
PD_RS03165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PD_RS03200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PD_RS03210	COG0514	ATP-dependent DNA helicase (RecQ)
PD_RS03215	COG0783	Belongs to the Dps family
PD_RS03220	COG1643	Atp-dependent helicase
PD_RS03230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PD_RS03235	COG1845	cytochrome c oxidase, subunit III
PD_RS03240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PD_RS03245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PD_RS03250	COG0142	geranyltranstransferase activity
PD_RS03260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PD_RS03280	COG2239	Acts as a magnesium transporter
PD_RS03290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PD_RS03325	COG1137	ATPase activity
PD_RS03340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PD_RS03350	COG0271	Belongs to the BolA IbaG family
PD_RS03390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PD_RS03400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PD_RS03435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PD_RS03465	COG0542	response to heat
PD_RS03485	COG0492	ferredoxin-NADP+ reductase activity
PD_RS03505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PD_RS03520	COG4191	Histidine kinase
PD_RS03525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PD_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
PD_RS03560	COG1609	Transcriptional regulator
PD_RS03565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PD_RS03570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PD_RS03575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PD_RS03585	COG0726	polysaccharide deacetylase
PD_RS03590	COG0297	glycogen (starch) synthase activity
PD_RS03610	COG0719	Fe-S assembly protein
PD_RS03615	COG0396	ATPase activity
PD_RS03620	COG0719	Fe-S assembly protein
PD_RS03625	COG1959	2 iron, 2 sulfur cluster binding
PD_RS03675	COG0308	aminopeptidase N
PD_RS03725	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PD_RS03750	COG1561	YicC-like family, N-terminal region
PD_RS03765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PD_RS03800	COG5295	Hep Hag repeat protein
PD_RS03805	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PD_RS03810	COG1459	type II secretion system
PD_RS03815	COG2165	general secretion pathway protein
PD_RS03820	COG4970	Tfp pilus assembly protein FimT
PD_RS03825	COG2165	general secretion pathway protein
PD_RS03830	COG4795	General secretion pathway protein
PD_RS03835	COG3156	type II secretion system protein K
PD_RS03840	COG3166	PFAM Fimbrial assembly family protein
PD_RS03855	COG1450	Type ii and iii secretion system protein
PD_RS03870	COG3634	alkyl hydroperoxide reductase activity
PD_RS03875	COG0583	DNA-binding transcription factor activity
PD_RS03935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PD_RS03960	COG0567	Dehydrogenase, E1 component
PD_RS03965	COG2850	peptidyl-arginine hydroxylation
PD_RS03985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PD_RS04080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PD_RS04085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PD_RS04090	COG2902	Dehydrogenase
PD_RS04130	COG2925	Exonuclease
PD_RS04145	COG0025	NhaP-type Na H and K H
PD_RS04165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PD_RS04185	COG0006	proline dipeptidase activity
PD_RS04195	COG0778	Nitroreductase
PD_RS04220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PD_RS04260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PD_RS04270	COG0557	exoribonuclease II activity
PD_RS04280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PD_RS04295	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PD_RS04300	COG1289	transmembrane transporter activity
PD_RS04330	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PD_RS04340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PD_RS04360	COG0596	Alpha beta hydrolase
PD_RS04365	COG0727	PFAM Uncharacterised protein family (UPF0153)
PD_RS04410	COG0840	transmembrane signaling receptor activity
PD_RS04415	COG2198	Histidine kinase
PD_RS04415	COG0643	Histidine kinase
PD_RS04415	COG0784	Response regulator, receiver
PD_RS04445	COG0285	dihydrofolate synthase activity
PD_RS04455	COG0339	signal peptide processing
PD_RS04480	COG1301	dicarboxylic acid transport
PD_RS04485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PD_RS04495	COG2091	lysine biosynthetic process via aminoadipic acid
PD_RS04545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PD_RS04590	COG0084	hydrolase, TatD family'
PD_RS04605	COG0552	protein localization to endoplasmic reticulum
PD_RS04645	COG0824	Thioesterase
PD_RS04670	COG2885	chlorophyll binding
PD_RS04680	COG0602	queuosine metabolic process
PD_RS04700	COG0386	Belongs to the glutathione peroxidase family
PD_RS04720	COG0406	alpha-ribazole phosphatase activity
PD_RS05080	COG2369	cell adhesion
PD_RS05185	COG0582	viral genome integration into host DNA
PD_RS05190	COG3567	Phage-associated protein, HI1409 family
PD_RS05195	COG5410	chromosome segregation
PD_RS05220	COG3772	lysozyme
PD_RS05255	COG3617	BRO family, N-terminal domain
PD_RS05330	COG5532	Uncharacterized conserved protein (DUF2303)
PD_RS05355	COG0629	single-stranded DNA binding
PD_RS05365	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PD_RS05370	COG3852	Histidine kinase
PD_RS05375	COG2204	response regulator
PD_RS05385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PD_RS05390	COG0004	ammonium transporteR
PD_RS05395	COG0347	Belongs to the P(II) protein family
PD_RS05400	COG0174	glutamine synthetase
PD_RS05410	COG2353	YceI-like domain
PD_RS05465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PD_RS05470	COG1764	response to oxidative stress
PD_RS05475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD_RS05520	COG1399	metal-binding, possibly nucleic acid-binding protein
PD_RS05530	COG0714	Associated with various cellular activities
PD_RS05550	COG0537	adenosine 5'-monophosphoramidase activity
PD_RS05565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PD_RS05600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PD_RS05625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PD_RS05625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PD_RS05675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PD_RS05690	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PD_RS05705	COG0251	oxidation-reduction process
PD_RS05770	COG3077	Addiction module antitoxin, RelB DinJ family
PD_RS05775	COG3041	Addiction module toxin RelE StbE family
PD_RS05845	COG3772	lysozyme
PD_RS05895	COG4197	protein conserved in bacteria, prophage-related
PD_RS06005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PD_RS06010	COG0392	lysyltransferase activity
PD_RS06010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PD_RS06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PD_RS06035	COG0463	Glycosyl transferase, family 2
PD_RS06085	COG3275	phosphorelay sensor kinase activity
PD_RS06090	COG0400	carboxylic ester hydrolase activity
PD_RS06110	COG2226	methyltransferase
PD_RS06135	COG2027	D-alanyl-D-alanine carboxypeptidase
PD_RS06145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PD_RS06175	COG0386	Belongs to the glutathione peroxidase family
PD_RS06180	COG1131	(ABC) transporter
PD_RS06210	COG3657	addiction module killer protein
PD_RS06215	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PD_RS06310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PD_RS06315	COG0488	(ABC) transporter
PD_RS06325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PD_RS06335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PD_RS06335	COG4651	solute:proton antiporter activity
PD_RS06395	COG0859	PFAM glycosyl transferase family 9
PD_RS06410	COG0631	protein serine/threonine phosphatase activity
PD_RS06415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PD_RS06440	COG2183	response to ionizing radiation
PD_RS06455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PD_RS06460	COG3118	belongs to the thioredoxin family
PD_RS06500	COG2951	lytic endotransglycosylase activity
PD_RS06505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PD_RS06645	COG0277	FAD linked oxidase domain protein
PD_RS06650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PD_RS06655	COG0531	amino acid
PD_RS06660	COG0531	amino acid
PD_RS06740	COG0460	homoserine dehydrogenase
PD_RS06740	COG0527	aspartate kinase activity
PD_RS06760	COG1686	Belongs to the peptidase S11 family
PD_RS06785	COG4953	penicillin-binding protein 1C
PD_RS06810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PD_RS06875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PD_RS06880	COG1506	peptidase
PD_RS06880	COG0823	Involved in the tonB-independent uptake of proteins
PD_RS06885	COG1297	OPT oligopeptide transporter protein
PD_RS06910	COG0676	glucose-6-phosphate 1-epimerase activity
PD_RS06920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PD_RS06925	COG1335	isochorismatase
PD_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
PD_RS06940	COG0463	Glycosyl transferase, family 2
PD_RS06955	COG1192	Involved in chromosome partitioning
PD_RS07015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PD_RS07065	COG0489	protein tyrosine kinase activity
PD_RS07075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PD_RS07175	COG1605	Chorismate mutase
PD_RS07175	COG0077	Prephenate dehydratase
PD_RS07190	COG1668	transmembrane transport
PD_RS07195	COG4555	ABC transporter
PD_RS07220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PD_RS07230	COG1605	Chorismate mutase
PD_RS07230	COG0287	Prephenate dehydrogenase
PD_RS07265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PD_RS07290	COG1278	Cold shock
PD_RS07300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PD_RS07310	COG2954	triphosphatase activity
PD_RS07325	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PD_RS07330	COG0438	transferase activity, transferring glycosyl groups
PD_RS07345	COG0438	transferase activity, transferring glycosyl groups
PD_RS07405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PD_RS07410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PD_RS07425	COG1064	alcohol dehydrogenase
PD_RS07440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PD_RS07450	COG0436	Aminotransferase
PD_RS07545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PD_RS07545	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PD_RS07600	COG0196	riboflavin kinase activity
PD_RS07605	COG0728	peptidoglycan biosynthetic process
PD_RS07610	COG0268	Binds directly to 16S ribosomal RNA
PD_RS07660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PD_RS07675	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
PD_RS07725	COG0395	ABC-type sugar transport system, permease component
PD_RS07730	COG1175	transmembrane transport
PD_RS07755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PD_RS07775	COG0436	Aminotransferase
PD_RS07830	COG5434	Belongs to the glycosyl hydrolase 28 family
PD_RS07850	COG0402	S-adenosylhomocysteine deaminase activity
PD_RS07860	COG1509	lysine 2,3-aminomutase activity
PD_RS07895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PD_RS07900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PD_RS07915	COG1028	Short-chain dehydrogenase reductase Sdr
PD_RS07960	COG0142	geranyltranstransferase activity
PD_RS07980	COG1301	dicarboxylic acid transport
PD_RS07990	COG0791	NLP P60 protein
PD_RS07995	COG0791	NLP P60 protein
PD_RS08005	COG2311	Membrane
PD_RS08015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PD_RS08065	COG0351	phosphomethylpyrimidine kinase
PD_RS08065	COG0352	thiamine-phosphate diphosphorylase activity
PD_RS08075	COG1324	tolerance protein
PD_RS08110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD_RS08115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PD_RS08120	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PD_RS08135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PD_RS08155	COG4774	siderophore transport
PD_RS08180	COG1477	protein flavinylation
PD_RS08185	COG1555	photosystem II stabilization
PD_RS08190	COG3178	'Phosphotransferase
PD_RS08195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PD_RS08205	COG0628	permease
PD_RS08225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PD_RS08245	COG3590	peptidase
PD_RS08295	COG0805	protein transport
PD_RS08310	COG0519	Catalyzes the synthesis of GMP from XMP
PD_RS08310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PD_RS08320	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
PD_RS08340	COG3107	peptidoglycan biosynthetic process
PD_RS08365	COG2878	Part of a membrane complex involved in electron transport
PD_RS08430	COG0629	single-stranded DNA binding
PD_RS08455	COG0827	DNA restriction-modification system
PD_RS08460	COG0827	DNA restriction-modification system
PD_RS08495	COG4968	Prepilin-type N-terminal cleavage methylation domain
PD_RS08500	COG1611	Belongs to the LOG family
PD_RS08505	COG4943	cyclic-guanylate-specific phosphodiesterase activity
PD_RS08510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PD_RS08520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PD_RS08550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PD_RS08565	COG0330	HflC and HflK could
PD_RS08570	COG0330	HflC and HflK could
PD_RS08575	COG0604	alcohol dehydrogenase
PD_RS08605	COG1183	phosphatidylcholine synthase activity
PD_RS08625	COG0668	transmembrane transport
PD_RS08630	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PD_RS08645	COG1610	YqeY-like protein
PD_RS08655	COG0358	DNA primase activity
PD_RS08690	COG1074	ATP-dependent DNA helicase activity
PD_RS08695	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PD_RS08700	COG1127	ABC transporter
PD_RS08705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PD_RS08725	COG2853	Lipoprotein
PD_RS08740	COG1116	anion transmembrane transporter activity
PD_RS08750	COG0531	amino acid
PD_RS08755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PD_RS08760	COG0861	Integral membrane protein TerC family
PD_RS08790	COG2193	ferroxidase activity
PD_RS08880	COG2194	sulfuric ester hydrolase activity
PD_RS08920	COG0667	Aldo Keto reductase
PD_RS08925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PD_RS08935	COG0305	Participates in initiation and elongation during chromosome replication
PD_RS08955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PD_RS08965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PD_RS08970	COG0277	FAD linked oxidase domain protein
PD_RS08995	COG4206	TonB-dependent receptor
PD_RS09100	COG3617	BRO family, N-terminal domain
PD_RS09175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PD_RS09180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PD_RS09185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PD_RS09200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PD_RS09225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PD_RS09225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PD_RS09245	COG0488	(ABC) transporter
PD_RS09255	COG3011	Protein conserved in bacteria
PD_RS09280	COG1918	ferrous iron import across plasma membrane
PD_RS09280	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PD_RS09290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PD_RS09315	COG0758	DNA mediated transformation
PD_RS09360	COG2969	positive regulation of protein catabolic process
PD_RS09365	COG0625	glutathione transferase activity
PD_RS09370	COG2857	Cytochrome c1
PD_RS09375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PD_RS09380	COG0723	plastoquinol--plastocyanin reductase activity
PD_RS09385	COG0741	lytic transglycosylase activity
PD_RS09395	COG1702	phosphate starvation-inducible protein PhoH
PD_RS09410	COG4535	Mg2 and Co2 transporter CorC
PD_RS09420	COG0598	Magnesium transport protein CorA
PD_RS09540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PD_RS09550	COG1199	ATP-dependent helicase activity
PD_RS09560	COG0288	reversible hydration of carbon dioxide
PD_RS09580	COG2011	ABC-type metal ion transport system permease component
PD_RS09595	COG0508	dehydrogenase complex catalyzes the overall conversion of
PD_RS09600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PD_RS09610	COG0626	cystathionine gamma-synthase activity
PD_RS09615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PD_RS09620	COG0739	heme binding
PD_RS09640	COG1238	metal cluster binding
PD_RS09655	COG5002	protein histidine kinase activity
PD_RS09680	COG3858	chitin binding
PD_RS09680	COG1388	LysM domain
PD_RS09685	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PD_RS09695	COG1472	Belongs to the glycosyl hydrolase 3 family
PD_RS09710	COG3537	Alpha-1,2-mannosidase
PD_RS09740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD_RS09745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PD_RS09785	COG0469	pyruvate kinase activity
PD_RS09805	COG0735	belongs to the Fur family
PD_RS09815	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PD_RS09815	COG5297	Belongs to the glycosyl hydrolase family 6
PD_RS09840	COG4305	rare lipoprotein A
PD_RS09850	COG0739	heme binding
PD_RS09865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PD_RS09875	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PD_RS09905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PD_RS09920	COG3116	cell division
PD_RS09935	COG3273	potassium ion transport
PD_RS09935	COG0471	metal ion transport
PD_RS09990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PD_RS10050	COG0860	N-Acetylmuramoyl-L-alanine amidase
PD_RS10055	COG0802	atpase or kinase
PD_RS10060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PD_RS10060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PD_RS10170	COG0745	RESPONSE REGULATOR receiver
PD_RS10175	COG0642	Histidine kinase
PD_RS10185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PD_RS10230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PD_RS10240	COG2831	hemolysin activation secretion protein
PD_RS10265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
PD_RS10310	COG0316	Belongs to the HesB IscA family
PD_RS10345	COG0697	spore germination
PD_RS10350	COG0671	phosphoesterase, PA-phosphatase related
PD_RS10365	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PD_RS10385	COG1132	(ABC) transporter
PD_RS10395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PD_RS10400	COG1538	Outer membrane efflux protein
PD_RS10425	COG0745	RESPONSE REGULATOR receiver
PD_RS10430	COG4783	chaperone-mediated protein folding
PD_RS10440	COG0473	3-isopropylmalate dehydrogenase activity
PD_RS10450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PD_RS10455	COG3083	sulfuric ester hydrolase activity
PD_RS10460	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PD_RS10485	COG0564	pseudouridine synthase activity
PD_RS10490	COG1530	ribonuclease E activity
PD_RS10495	COG2197	response regulator
PD_RS10515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PD_RS10530	COG0488	(ABC) transporter
PD_RS10545	COG1278	Cold shock
PD_RS10645	COG0012	GTP binding
PD_RS10730	COG2095	MarC family integral membrane protein
PD_RS10735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PD_RS10765	COG2132	Multicopper oxidase
PD_RS10775	COG0210	DNA helicase
PD_RS10785	COG0616	signal peptide processing
PD_RS10805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PD_RS10820	COG2201	protein-glutamate methylesterase activity
PD_RS10825	COG2177	Part of the ABC transporter FtsEX involved in
PD_RS10830	COG2884	Cell division ATP-binding protein ftsE
PD_RS10840	COG3118	belongs to the thioredoxin family
PD_RS10845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PD_RS10855	COG0793	Belongs to the peptidase S41A family
PD_RS10860	COG4942	peptidase
PD_RS10875	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PD_RS10880	COG0493	'glutamate synthase
PD_RS10885	COG0070	glutamate synthase
PD_RS10885	COG0067	glutamate synthase
PD_RS10885	COG0069	glutamate synthase activity
PD_RS10935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PD_RS10985	COG4942	peptidase
PD_RS11115	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PD_RS11120	COG3657	addiction module killer protein
PD_RS11295	COG3617	BRO family, N-terminal domain