locus-tag	class	description
IUD20_RS00010	COG0592	DNA-directed DNA polymerase activity
IUD20_RS00020	COG0187	DNA topoisomerase II activity
IUD20_RS00030	COG0501	Belongs to the peptidase M48B family
IUD20_RS00060	COG1506	peptidase
IUD20_RS00060	COG4946	Tricorn protease homolog
IUD20_RS00060	COG0823	Involved in the tonB-independent uptake of proteins
IUD20_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUD20_RS00150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUD20_RS00160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUD20_RS00170	COG0511	ligase activity, forming carbon-carbon bonds
IUD20_RS00175	COG0439	Biotin carboxylase
IUD20_RS00180	COG0210	DNA helicase
IUD20_RS00210	COG1040	competence protein
IUD20_RS00220	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUD20_RS00260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUD20_RS00270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUD20_RS00295	COG3121	Chaperone
IUD20_RS00300	COG3539	Fimbrial protein
IUD20_RS00310	COG1546	Belongs to the CinA family
IUD20_RS00315	COG0477	Major facilitator Superfamily
IUD20_RS00320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUD20_RS00335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IUD20_RS00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUD20_RS00350	COG1534	Rna-binding protein
IUD20_RS00380	COG1560	Kdo2-lipid A biosynthetic process
IUD20_RS00385	COG1519	Transferase
IUD20_RS00425	COG1393	Belongs to the ArsC family
IUD20_RS00435	COG0367	asparagine synthase
IUD20_RS00445	COG2070	2-Nitropropane dioxygenase
IUD20_RS00475	COG0339	signal peptide processing
IUD20_RS00490	COG2132	Multicopper oxidase
IUD20_RS00520	COG0795	lipopolysaccharide-transporting ATPase activity
IUD20_RS00555	COG4221	oxidoreductase activity
IUD20_RS00575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUD20_RS00585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD20_RS00640	COG2223	nitrite transmembrane transporter activity
IUD20_RS00650	COG0739	heme binding
IUD20_RS00685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUD20_RS00700	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_RS00710	COG1272	protein, Hemolysin III
IUD20_RS00715	COG0463	Glycosyl transferase, family 2
IUD20_RS00720	COG0084	hydrolase, TatD family'
IUD20_RS00750	COG0330	HflC and HflK could
IUD20_RS00755	COG3956	TIGRFAM MazG family protein
IUD20_RS00760	COG1218	3'(2'),5'-bisphosphate nucleotidase
IUD20_RS00765	COG0494	nUDIX hydrolase
IUD20_RS00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUD20_RS00780	COG0513	Belongs to the DEAD box helicase family
IUD20_RS00785	COG0720	synthase
IUD20_RS00810	COG1981	membrane
IUD20_RS00845	COG0512	Glutamine amidotransferase of anthranilate synthase
IUD20_RS00875	COG0006	proline dipeptidase activity
IUD20_RS00895	COG1862	Preprotein translocase
IUD20_RS00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUD20_RS00905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUD20_RS00915	COG0617	tRNA 3'-terminal CCA addition
IUD20_RS00955	COG0195	Participates in both transcription termination and antitermination
IUD20_RS00985	COG1733	regulation of RNA biosynthetic process
IUD20_RS00990	COG0702	epimerase
IUD20_RS01035	COG2086	electron transfer activity
IUD20_RS01065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD20_RS01095	COG0477	Major facilitator Superfamily
IUD20_RS01115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUD20_RS01120	COG0671	phosphoesterase, PA-phosphatase related
IUD20_RS01135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUD20_RS01140	COG0628	permease
IUD20_RS01160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUD20_RS01165	COG1090	epimerase
IUD20_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
IUD20_RS01190	COG1049	propionate catabolic process, 2-methylcitrate cycle
IUD20_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD20_RS01260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUD20_RS01280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IUD20_RS01285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IUD20_RS01290	COG1034	ATP synthesis coupled electron transport
IUD20_RS01325	COG1007	ATP synthesis coupled electron transport
IUD20_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_RS01335	COG2851	Citrate transporter
IUD20_RS01350	COG0642	Histidine kinase
IUD20_RS01365	COG0784	Response regulator, receiver
IUD20_RS01365	COG2205	protein histidine kinase activity
IUD20_RS01385	COG0280	phosphate acetyltransferase
IUD20_RS01385	COG0281	malic enzyme
IUD20_RS01395	COG0742	ribosomal rna small subunit methyltransferase
IUD20_RS01415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUD20_RS01435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IUD20_RS01460	COG2166	iron-sulfur cluster assembly
IUD20_RS01485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUD20_RS01560	COG1321	iron dependent repressor
IUD20_RS01580	COG1946	Acyl-CoA thioesterase
IUD20_RS01665	COG0575	Belongs to the CDS family
IUD20_RS01760	COG0354	folic acid binding
IUD20_RS01770	COG2009	succinate dehydrogenase
IUD20_RS01775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUD20_RS01785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUD20_RS01815	COG0811	peptide transport
IUD20_RS01865	COG3093	addiction module antidote protein HigA
IUD20_RS01875	COG2944	sequence-specific DNA binding
IUD20_RS01940	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_RS01960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD20_RS02030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IUD20_RS02055	COG1024	Enoyl-CoA hydratase
IUD20_RS02060	COG0019	diaminopimelate decarboxylase activity
IUD20_RS02080	COG0494	nUDIX hydrolase
IUD20_RS02085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUD20_RS02110	COG0312	modulator of DNA gyrase
IUD20_RS02120	COG0312	modulator of DNA gyrase
IUD20_RS02125	COG0583	DNA-binding transcription factor activity
IUD20_RS02140	COG1064	alcohol dehydrogenase
IUD20_RS02195	COG0356	it plays a direct role in the translocation of protons across the membrane
IUD20_RS02315	COG0201	protein transport
IUD20_RS02345	COG2960	long-chain fatty acid transporting porin activity
IUD20_RS02350	COG0606	chelatase, subunit chli
IUD20_RS02375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IUD20_RS02435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUD20_RS02440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUD20_RS02455	COG1187	pseudouridine synthase activity
IUD20_RS02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUD20_RS02480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD20_RS02485	COG0625	glutathione transferase activity
IUD20_RS02495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUD20_RS02500	COG1217	gtp-binding protein TYPA
IUD20_RS02540	COG0842	Transport permease protein
IUD20_RS02545	COG1131	(ABC) transporter
IUD20_RS02565	COG1643	Atp-dependent helicase
IUD20_RS02575	COG1956	GAF domain-containing protein
IUD20_RS02580	COG0729	surface antigen
IUD20_RS02585	COG2911	Protein conserved in bacteria
IUD20_RS02595	COG0582	viral genome integration into host DNA
IUD20_RS02765	COG0668	transmembrane transport
IUD20_RS02795	COG5297	Belongs to the glycosyl hydrolase family 6
IUD20_RS02830	COG2733	membrane
IUD20_RS02835	COG1253	flavin adenine dinucleotide binding
IUD20_RS02900	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IUD20_RS02900	COG0644	oxidoreductase
IUD20_RS02915	COG3218	ABC-type transport auxiliary lipoprotein component
IUD20_RS02915	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUD20_RS02920	COG1127	ABC transporter
IUD20_RS02925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUD20_RS02960	COG1077	Cell shape determining protein MreB Mrl
IUD20_RS02965	COG1792	Involved in formation and maintenance of cell shape
IUD20_RS02970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IUD20_RS02975	COG0768	penicillin binding
IUD20_RS02980	COG0772	Belongs to the SEDS family
IUD20_RS02990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUD20_RS03010	COG2894	cell division
IUD20_RS03030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IUD20_RS03045	COG2353	YceI-like domain
IUD20_RS03115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUD20_RS03120	COG4208	sulfate ABC transporter
IUD20_RS03145	COG1846	Transcriptional regulator
IUD20_RS03185	COG0741	lytic transglycosylase activity
IUD20_RS03195	COG1999	signal sequence binding
IUD20_RS03220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUD20_RS03255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUD20_RS03265	COG0514	ATP-dependent DNA helicase (RecQ)
IUD20_RS03270	COG0783	Belongs to the Dps family
IUD20_RS03275	COG1643	Atp-dependent helicase
IUD20_RS03285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUD20_RS03290	COG1845	cytochrome c oxidase, subunit III
IUD20_RS03295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUD20_RS03300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUD20_RS03305	COG0142	geranyltranstransferase activity
IUD20_RS03320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUD20_RS03340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUD20_RS03375	COG1137	ATPase activity
IUD20_RS03390	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUD20_RS03400	COG0271	Belongs to the BolA IbaG family
IUD20_RS03440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUD20_RS03450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUD20_RS03485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUD20_RS03515	COG0542	response to heat
IUD20_RS03535	COG0492	ferredoxin-NADP+ reductase activity
IUD20_RS03555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUD20_RS03565	COG4191	Histidine kinase
IUD20_RS03570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IUD20_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_RS03605	COG1609	Transcriptional regulator
IUD20_RS03610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUD20_RS03615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUD20_RS03620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUD20_RS03630	COG0726	polysaccharide deacetylase
IUD20_RS03635	COG0297	glycogen (starch) synthase activity
IUD20_RS03655	COG0719	Fe-S assembly protein
IUD20_RS03660	COG0396	ATPase activity
IUD20_RS03665	COG0719	Fe-S assembly protein
IUD20_RS03670	COG1959	2 iron, 2 sulfur cluster binding
IUD20_RS03725	COG0308	aminopeptidase N
IUD20_RS03775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUD20_RS03800	COG1561	YicC-like family, N-terminal region
IUD20_RS03815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUD20_RS03850	COG5295	Hep Hag repeat protein
IUD20_RS03855	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUD20_RS03860	COG1459	type II secretion system
IUD20_RS03865	COG2165	general secretion pathway protein
IUD20_RS03870	COG4970	Tfp pilus assembly protein FimT
IUD20_RS03875	COG2165	general secretion pathway protein
IUD20_RS03880	COG4795	General secretion pathway protein
IUD20_RS03885	COG3156	type II secretion system protein K
IUD20_RS03890	COG3166	PFAM Fimbrial assembly family protein
IUD20_RS03905	COG1450	Type ii and iii secretion system protein
IUD20_RS03920	COG3634	alkyl hydroperoxide reductase activity
IUD20_RS03925	COG0583	DNA-binding transcription factor activity
IUD20_RS03985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUD20_RS04010	COG0567	Dehydrogenase, E1 component
IUD20_RS04015	COG2850	peptidyl-arginine hydroxylation
IUD20_RS04030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_RS04130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUD20_RS04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD20_RS04140	COG2902	Dehydrogenase
IUD20_RS04180	COG2925	Exonuclease
IUD20_RS04190	COG0025	NhaP-type Na H and K H
IUD20_RS04210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUD20_RS04235	COG0006	proline dipeptidase activity
IUD20_RS04245	COG0778	Nitroreductase
IUD20_RS04280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUD20_RS04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUD20_RS04330	COG0557	exoribonuclease II activity
IUD20_RS04340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IUD20_RS04355	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IUD20_RS04360	COG1289	transmembrane transporter activity
IUD20_RS04380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IUD20_RS04390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUD20_RS04405	COG0596	Alpha beta hydrolase
IUD20_RS04410	COG0727	PFAM Uncharacterised protein family (UPF0153)
IUD20_RS04455	COG0840	transmembrane signaling receptor activity
IUD20_RS04460	COG0643	Histidine kinase
IUD20_RS04460	COG0784	Response regulator, receiver
IUD20_RS04460	COG2198	Histidine kinase
IUD20_RS04490	COG0285	dihydrofolate synthase activity
IUD20_RS04500	COG0339	signal peptide processing
IUD20_RS04520	COG1301	dicarboxylic acid transport
IUD20_RS04525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUD20_RS04535	COG2091	lysine biosynthetic process via aminoadipic acid
IUD20_RS04575	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUD20_RS04605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUD20_RS04605	COG0512	Glutamine amidotransferase of anthranilate synthase
IUD20_RS04625	COG0084	hydrolase, TatD family'
IUD20_RS04645	COG0552	protein localization to endoplasmic reticulum
IUD20_RS04690	COG0824	Thioesterase
IUD20_RS04715	COG2885	chlorophyll binding
IUD20_RS04725	COG0602	queuosine metabolic process
IUD20_RS04745	COG0386	Belongs to the glutathione peroxidase family
IUD20_RS04765	COG0406	alpha-ribazole phosphatase activity
IUD20_RS05135	COG0675	Transposase, IS605 OrfB family
IUD20_RS05295	COG2369	cell adhesion
IUD20_RS05330	COG3210	domain, Protein
IUD20_RS05345	COG0582	viral genome integration into host DNA
IUD20_RS05350	COG3567	Phage-associated protein, HI1409 family
IUD20_RS05355	COG5410	chromosome segregation
IUD20_RS05380	COG3772	lysozyme
IUD20_RS05415	COG3617	BRO family, N-terminal domain
IUD20_RS05500	COG5532	Uncharacterized conserved protein (DUF2303)
IUD20_RS05530	COG0629	single-stranded DNA binding
IUD20_RS05540	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_RS05545	COG3852	Histidine kinase
IUD20_RS05550	COG2204	response regulator
IUD20_RS05565	COG0004	ammonium transporteR
IUD20_RS05570	COG0347	Belongs to the P(II) protein family
IUD20_RS05575	COG0174	glutamine synthetase
IUD20_RS05585	COG2353	YceI-like domain
IUD20_RS05640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUD20_RS05645	COG1764	response to oxidative stress
IUD20_RS05650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD20_RS05695	COG1399	metal-binding, possibly nucleic acid-binding protein
IUD20_RS05705	COG0714	Associated with various cellular activities
IUD20_RS05725	COG0537	adenosine 5'-monophosphoramidase activity
IUD20_RS05740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUD20_RS05780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUD20_RS05805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IUD20_RS05805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IUD20_RS05855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUD20_RS05870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IUD20_RS05885	COG0251	oxidation-reduction process
IUD20_RS05950	COG3077	Addiction module antitoxin, RelB DinJ family
IUD20_RS05955	COG3041	Addiction module toxin RelE StbE family
IUD20_RS06025	COG3772	lysozyme
IUD20_RS06090	COG4197	protein conserved in bacteria, prophage-related
IUD20_RS06160	COG3617	BRO family, N-terminal domain
IUD20_RS06200	COG0392	lysyltransferase activity
IUD20_RS06200	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IUD20_RS06210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUD20_RS06220	COG0463	Glycosyl transferase, family 2
IUD20_RS06265	COG3275	phosphorelay sensor kinase activity
IUD20_RS06270	COG0400	carboxylic ester hydrolase activity
IUD20_RS06290	COG2226	methyltransferase
IUD20_RS06315	COG2027	D-alanyl-D-alanine carboxypeptidase
IUD20_RS06325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUD20_RS06355	COG0386	Belongs to the glutathione peroxidase family
IUD20_RS06360	COG1131	(ABC) transporter
IUD20_RS06390	COG3657	addiction module killer protein
IUD20_RS06395	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUD20_RS06500	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD20_RS06505	COG0488	(ABC) transporter
IUD20_RS06515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IUD20_RS06525	COG4651	solute:proton antiporter activity
IUD20_RS06525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUD20_RS06585	COG0859	PFAM glycosyl transferase family 9
IUD20_RS06600	COG0631	protein serine/threonine phosphatase activity
IUD20_RS06605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUD20_RS06635	COG2183	response to ionizing radiation
IUD20_RS06650	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUD20_RS06655	COG3118	belongs to the thioredoxin family
IUD20_RS06700	COG2951	lytic endotransglycosylase activity
IUD20_RS06705	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IUD20_RS06820	COG0277	FAD linked oxidase domain protein
IUD20_RS06825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUD20_RS06830	COG0531	amino acid
IUD20_RS06920	COG0460	homoserine dehydrogenase
IUD20_RS06920	COG0527	aspartate kinase activity
IUD20_RS06940	COG1686	Belongs to the peptidase S11 family
IUD20_RS06965	COG4953	penicillin-binding protein 1C
IUD20_RS06990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUD20_RS07055	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD20_RS07060	COG1506	peptidase
IUD20_RS07060	COG0823	Involved in the tonB-independent uptake of proteins
IUD20_RS07065	COG1297	OPT oligopeptide transporter protein
IUD20_RS07095	COG0676	glucose-6-phosphate 1-epimerase activity
IUD20_RS07105	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUD20_RS07110	COG1335	isochorismatase
IUD20_RS07115	COG0318	PFAM AMP-dependent synthetase and ligase
IUD20_RS07125	COG0463	Glycosyl transferase, family 2
IUD20_RS07140	COG1192	Involved in chromosome partitioning
IUD20_RS07200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUD20_RS07245	COG0489	protein tyrosine kinase activity
IUD20_RS07255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUD20_RS07350	COG0077	Prephenate dehydratase
IUD20_RS07350	COG1605	Chorismate mutase
IUD20_RS07365	COG1668	transmembrane transport
IUD20_RS07370	COG4555	ABC transporter
IUD20_RS07395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUD20_RS07405	COG0287	Prephenate dehydrogenase
IUD20_RS07405	COG1605	Chorismate mutase
IUD20_RS07440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD20_RS07465	COG1278	Cold shock
IUD20_RS07475	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IUD20_RS07485	COG2954	triphosphatase activity
IUD20_RS07500	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IUD20_RS07505	COG0438	transferase activity, transferring glycosyl groups
IUD20_RS07515	COG0438	transferase activity, transferring glycosyl groups
IUD20_RS07580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD20_RS07585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUD20_RS07600	COG1064	alcohol dehydrogenase
IUD20_RS07615	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUD20_RS07625	COG0436	Aminotransferase
IUD20_RS07705	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IUD20_RS07705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD20_RS07755	COG0196	riboflavin kinase activity
IUD20_RS07760	COG0728	peptidoglycan biosynthetic process
IUD20_RS07765	COG0268	Binds directly to 16S ribosomal RNA
IUD20_RS07815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUD20_RS07830	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUD20_RS07885	COG0395	ABC-type sugar transport system, permease component
IUD20_RS07890	COG1175	transmembrane transport
IUD20_RS07920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUD20_RS07940	COG0436	Aminotransferase
IUD20_RS08000	COG5434	Belongs to the glycosyl hydrolase 28 family
IUD20_RS08025	COG0402	S-adenosylhomocysteine deaminase activity
IUD20_RS08035	COG1509	lysine 2,3-aminomutase activity
IUD20_RS08070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUD20_RS08075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUD20_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
IUD20_RS08140	COG0142	geranyltranstransferase activity
IUD20_RS08165	COG1301	dicarboxylic acid transport
IUD20_RS08175	COG0791	NLP P60 protein
IUD20_RS08180	COG0791	NLP P60 protein
IUD20_RS08190	COG2311	Membrane
IUD20_RS08205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUD20_RS08260	COG0352	thiamine-phosphate diphosphorylase activity
IUD20_RS08260	COG0351	phosphomethylpyrimidine kinase
IUD20_RS08270	COG1324	tolerance protein
IUD20_RS08305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD20_RS08310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD20_RS08315	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IUD20_RS08330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUD20_RS08350	COG4774	siderophore transport
IUD20_RS08375	COG1477	protein flavinylation
IUD20_RS08380	COG1555	photosystem II stabilization
IUD20_RS08385	COG3178	'Phosphotransferase
IUD20_RS08390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IUD20_RS08400	COG0628	permease
IUD20_RS08420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUD20_RS08445	COG3590	peptidase
IUD20_RS08495	COG0805	protein transport
IUD20_RS08505	COG0519	Catalyzes the synthesis of GMP from XMP
IUD20_RS08505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUD20_RS08515	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IUD20_RS08530	COG3107	peptidoglycan biosynthetic process
IUD20_RS08555	COG2878	Part of a membrane complex involved in electron transport
IUD20_RS08630	COG0629	single-stranded DNA binding
IUD20_RS08660	COG0827	DNA restriction-modification system
IUD20_RS08665	COG0827	DNA restriction-modification system
IUD20_RS08705	COG4968	Prepilin-type N-terminal cleavage methylation domain
IUD20_RS08710	COG1611	Belongs to the LOG family
IUD20_RS08715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUD20_RS08720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUD20_RS08730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD20_RS08760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUD20_RS08775	COG0330	HflC and HflK could
IUD20_RS08780	COG0330	HflC and HflK could
IUD20_RS08785	COG0604	alcohol dehydrogenase
IUD20_RS08815	COG1183	phosphatidylcholine synthase activity
IUD20_RS08835	COG0668	transmembrane transport
IUD20_RS08840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IUD20_RS08855	COG1610	YqeY-like protein
IUD20_RS08865	COG0358	DNA primase activity
IUD20_RS08900	COG1074	ATP-dependent DNA helicase activity
IUD20_RS08905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IUD20_RS08910	COG1127	ABC transporter
IUD20_RS08915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUD20_RS08935	COG2853	Lipoprotein
IUD20_RS08945	COG1116	anion transmembrane transporter activity
IUD20_RS08955	COG0531	amino acid
IUD20_RS08960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUD20_RS08965	COG0861	Integral membrane protein TerC family
IUD20_RS09000	COG2193	ferroxidase activity
IUD20_RS09090	COG2194	sulfuric ester hydrolase activity
IUD20_RS09130	COG0667	Aldo Keto reductase
IUD20_RS09135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUD20_RS09145	COG0305	Participates in initiation and elongation during chromosome replication
IUD20_RS09175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUD20_RS09185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUD20_RS09190	COG0277	FAD linked oxidase domain protein
IUD20_RS09205	COG4206	TonB-dependent receptor
IUD20_RS09305	COG3617	BRO family, N-terminal domain
IUD20_RS09375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUD20_RS09395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IUD20_RS09420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUD20_RS09420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUD20_RS09440	COG0488	(ABC) transporter
IUD20_RS09450	COG3011	Protein conserved in bacteria
IUD20_RS09475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IUD20_RS09475	COG1918	ferrous iron import across plasma membrane
IUD20_RS09485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUD20_RS09510	COG0758	DNA mediated transformation
IUD20_RS09555	COG2969	positive regulation of protein catabolic process
IUD20_RS09560	COG0625	glutathione transferase activity
IUD20_RS09565	COG2857	Cytochrome c1
IUD20_RS09570	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUD20_RS09575	COG0723	plastoquinol--plastocyanin reductase activity
IUD20_RS09580	COG0741	lytic transglycosylase activity
IUD20_RS09590	COG1702	phosphate starvation-inducible protein PhoH
IUD20_RS09605	COG4535	Mg2 and Co2 transporter CorC
IUD20_RS09615	COG0598	Magnesium transport protein CorA
IUD20_RS09670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUD20_RS09680	COG1199	ATP-dependent helicase activity
IUD20_RS09690	COG0288	reversible hydration of carbon dioxide
IUD20_RS09715	COG2011	ABC-type metal ion transport system permease component
IUD20_RS09735	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUD20_RS09740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUD20_RS09755	COG0626	cystathionine gamma-synthase activity
IUD20_RS09760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUD20_RS09765	COG0739	heme binding
IUD20_RS09785	COG1238	metal cluster binding
IUD20_RS09800	COG5002	protein histidine kinase activity
IUD20_RS09820	COG1388	LysM domain
IUD20_RS09820	COG3858	chitin binding
IUD20_RS09825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IUD20_RS09835	COG1472	Belongs to the glycosyl hydrolase 3 family
IUD20_RS09850	COG3537	Alpha-1,2-mannosidase
IUD20_RS09875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUD20_RS09880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUD20_RS09925	COG0469	pyruvate kinase activity
IUD20_RS09945	COG0735	belongs to the Fur family
IUD20_RS09955	COG5297	Belongs to the glycosyl hydrolase family 6
IUD20_RS09955	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUD20_RS09980	COG4305	rare lipoprotein A
IUD20_RS09990	COG0739	heme binding
IUD20_RS10005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUD20_RS10015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUD20_RS10045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IUD20_RS10060	COG3116	cell division
IUD20_RS10075	COG3273	potassium ion transport
IUD20_RS10075	COG0471	metal ion transport
IUD20_RS10130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUD20_RS10190	COG0860	N-Acetylmuramoyl-L-alanine amidase
IUD20_RS10195	COG0802	atpase or kinase
IUD20_RS10200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUD20_RS10200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUD20_RS10300	COG0745	RESPONSE REGULATOR receiver
IUD20_RS10305	COG0642	Histidine kinase
IUD20_RS10315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IUD20_RS10360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IUD20_RS10370	COG2831	hemolysin activation secretion protein
IUD20_RS10395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IUD20_RS10435	COG0316	Belongs to the HesB IscA family
IUD20_RS10475	COG0697	spore germination
IUD20_RS10480	COG0671	phosphoesterase, PA-phosphatase related
IUD20_RS10495	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IUD20_RS10515	COG1132	(ABC) transporter
IUD20_RS10520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUD20_RS10525	COG1538	Outer membrane efflux protein
IUD20_RS10550	COG0745	RESPONSE REGULATOR receiver
IUD20_RS10555	COG4783	chaperone-mediated protein folding
IUD20_RS10565	COG0473	3-isopropylmalate dehydrogenase activity
IUD20_RS10575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUD20_RS10580	COG3083	sulfuric ester hydrolase activity
IUD20_RS10585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUD20_RS10610	COG0564	pseudouridine synthase activity
IUD20_RS10615	COG1530	ribonuclease E activity
IUD20_RS10620	COG2197	response regulator
IUD20_RS10635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUD20_RS10650	COG0488	(ABC) transporter
IUD20_RS10665	COG1278	Cold shock
IUD20_RS10765	COG0012	GTP binding
IUD20_RS10855	COG2095	MarC family integral membrane protein
IUD20_RS10865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUD20_RS10890	COG2132	Multicopper oxidase
IUD20_RS10900	COG0210	DNA helicase
IUD20_RS10910	COG0616	signal peptide processing
IUD20_RS10930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUD20_RS10950	COG2201	protein-glutamate methylesterase activity
IUD20_RS10955	COG2177	Part of the ABC transporter FtsEX involved in
IUD20_RS10960	COG2884	Cell division ATP-binding protein ftsE
IUD20_RS10970	COG3118	belongs to the thioredoxin family
IUD20_RS10975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IUD20_RS10990	COG0793	Belongs to the peptidase S41A family
IUD20_RS10995	COG4942	peptidase
IUD20_RS11010	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUD20_RS11015	COG0493	'glutamate synthase
IUD20_RS11020	COG0067	glutamate synthase
IUD20_RS11020	COG0069	glutamate synthase activity
IUD20_RS11020	COG0070	glutamate synthase
IUD20_RS11070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IUD20_RS11120	COG4942	peptidase
IUD20_RS11265	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUD20_RS11270	COG3657	addiction module killer protein
IUD20_RS11380	COG3451	type IV secretory pathway VirB4
IUD20_RS11435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IUD20_RS11540	COG0675	Transposase, IS605 OrfB family
IUD20_RS11560	COG0629	single-stranded DNA binding
IUD20_RS11570	COG4962	Type ii secretion system protein e