locus-tag	class	description
LZ758_RS00010	COG0592	DNA-directed DNA polymerase activity
LZ758_RS00020	COG0187	DNA topoisomerase II activity
LZ758_RS00030	COG0501	Belongs to the peptidase M48B family
LZ758_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ758_RS00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ758_RS00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ758_RS00165	COG0511	ligase activity, forming carbon-carbon bonds
LZ758_RS00170	COG0439	Biotin carboxylase
LZ758_RS00175	COG0210	DNA helicase
LZ758_RS00200	COG1040	competence protein
LZ758_RS00210	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ758_RS00260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ758_RS00290	COG3121	Chaperone
LZ758_RS00295	COG3539	Fimbrial protein
LZ758_RS00300	COG1546	Belongs to the CinA family
LZ758_RS00305	COG0477	Major facilitator Superfamily
LZ758_RS00310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ758_RS00325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ758_RS00340	COG1534	Rna-binding protein
LZ758_RS00370	COG1560	Kdo2-lipid A biosynthetic process
LZ758_RS00375	COG1519	Transferase
LZ758_RS00415	COG1393	Belongs to the ArsC family
LZ758_RS00425	COG0367	asparagine synthase
LZ758_RS00435	COG2070	2-Nitropropane dioxygenase
LZ758_RS00450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZ758_RS00465	COG0339	signal peptide processing
LZ758_RS00550	COG4221	oxidoreductase activity
LZ758_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ758_RS00580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ758_RS00635	COG2223	nitrite transmembrane transporter activity
LZ758_RS00645	COG0739	heme binding
LZ758_RS00680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ758_RS00695	COG1028	Short-chain dehydrogenase reductase Sdr
LZ758_RS00705	COG1272	protein, Hemolysin III
LZ758_RS00710	COG0463	Glycosyl transferase, family 2
LZ758_RS00715	COG0084	hydrolase, TatD family'
LZ758_RS00745	COG0330	HflC and HflK could
LZ758_RS00750	COG3956	TIGRFAM MazG family protein
LZ758_RS00755	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZ758_RS00760	COG0494	nUDIX hydrolase
LZ758_RS00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ758_RS00775	COG0513	Belongs to the DEAD box helicase family
LZ758_RS00780	COG0720	synthase
LZ758_RS00805	COG1981	membrane
LZ758_RS00840	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ758_RS00875	COG0006	proline dipeptidase activity
LZ758_RS00895	COG1862	Preprotein translocase
LZ758_RS00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ758_RS00905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ758_RS00915	COG0617	tRNA 3'-terminal CCA addition
LZ758_RS00955	COG0195	Participates in both transcription termination and antitermination
LZ758_RS00985	COG1733	regulation of RNA biosynthetic process
LZ758_RS00990	COG0702	epimerase
LZ758_RS01035	COG2086	electron transfer activity
LZ758_RS01065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ758_RS01095	COG0477	Major facilitator Superfamily
LZ758_RS01115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ758_RS01120	COG0671	phosphoesterase, PA-phosphatase related
LZ758_RS01135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ758_RS01140	COG0628	permease
LZ758_RS01160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ758_RS01165	COG1090	epimerase
LZ758_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
LZ758_RS01190	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ758_RS01230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ758_RS01255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ758_RS01275	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ758_RS01280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ758_RS01285	COG1034	ATP synthesis coupled electron transport
LZ758_RS01320	COG1007	ATP synthesis coupled electron transport
LZ758_RS01325	COG1028	Short-chain dehydrogenase reductase Sdr
LZ758_RS01330	COG2851	Citrate transporter
LZ758_RS01345	COG0642	Histidine kinase
LZ758_RS01360	COG2205	protein histidine kinase activity
LZ758_RS01360	COG0784	Response regulator, receiver
LZ758_RS01380	COG0280	phosphate acetyltransferase
LZ758_RS01380	COG0281	malic enzyme
LZ758_RS01390	COG0742	ribosomal rna small subunit methyltransferase
LZ758_RS01410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ758_RS01430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ758_RS01450	COG1199	ATP-dependent helicase activity
LZ758_RS01460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ758_RS01480	COG3210	domain, Protein
LZ758_RS01560	COG0598	Magnesium transport protein CorA
LZ758_RS01570	COG4535	Mg2 and Co2 transporter CorC
LZ758_RS01585	COG1702	phosphate starvation-inducible protein PhoH
LZ758_RS01595	COG0741	lytic transglycosylase activity
LZ758_RS01600	COG0723	plastoquinol--plastocyanin reductase activity
LZ758_RS01605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ758_RS01610	COG2857	Cytochrome c1
LZ758_RS01615	COG0625	glutathione transferase activity
LZ758_RS01620	COG2969	positive regulation of protein catabolic process
LZ758_RS01665	COG0758	DNA mediated transformation
LZ758_RS01690	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ758_RS01700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LZ758_RS01700	COG1918	ferrous iron import across plasma membrane
LZ758_RS01715	COG0564	pseudouridine synthase activity
LZ758_RS01730	COG3011	Protein conserved in bacteria
LZ758_RS01740	COG0488	(ABC) transporter
LZ758_RS01760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ758_RS01760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ758_RS01785	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ758_RS01805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ758_RS01850	COG0629	single-stranded DNA binding
LZ758_RS01855	COG3617	BRO family, N-terminal domain
LZ758_RS01870	COG5532	Uncharacterized conserved protein (DUF2303)
LZ758_RS01950	COG3617	BRO family, N-terminal domain
LZ758_RS01955	COG3617	BRO family, N-terminal domain
LZ758_RS01960	COG3617	BRO family, N-terminal domain
LZ758_RS02000	COG3772	lysozyme
LZ758_RS02025	COG5410	chromosome segregation
LZ758_RS02030	COG3567	Phage-associated protein, HI1409 family
LZ758_RS02035	COG0582	viral genome integration into host DNA
LZ758_RS02055	COG2369	cell adhesion
LZ758_RS02125	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ758_RS02130	COG3657	addiction module killer protein
LZ758_RS02165	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ758_RS02170	COG3657	addiction module killer protein
LZ758_RS02245	COG3617	BRO family, N-terminal domain
LZ758_RS02340	COG3617	BRO family, N-terminal domain
LZ758_RS02355	COG0305	Participates in initiation and elongation during chromosome replication
LZ758_RS02380	COG3772	lysozyme
LZ758_RS02405	COG5410	chromosome segregation
LZ758_RS02415	COG3567	Phage-associated protein, HI1409 family
LZ758_RS02420	COG0582	viral genome integration into host DNA
LZ758_RS02440	COG2369	cell adhesion
LZ758_RS02505	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ758_RS02510	COG3657	addiction module killer protein
LZ758_RS02545	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ758_RS02550	COG3657	addiction module killer protein
LZ758_RS02580	COG4206	TonB-dependent receptor
LZ758_RS02595	COG0277	FAD linked oxidase domain protein
LZ758_RS02600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ758_RS02610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ758_RS02635	COG0305	Participates in initiation and elongation during chromosome replication
LZ758_RS02645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ758_RS02650	COG0667	Aldo Keto reductase
LZ758_RS02690	COG2194	sulfuric ester hydrolase activity
LZ758_RS02775	COG2193	ferroxidase activity
LZ758_RS02805	COG0861	Integral membrane protein TerC family
LZ758_RS02810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ758_RS02815	COG0531	amino acid
LZ758_RS02825	COG1116	anion transmembrane transporter activity
LZ758_RS02835	COG2853	Lipoprotein
LZ758_RS02855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ758_RS02860	COG1127	ABC transporter
LZ758_RS02865	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ758_RS02870	COG1074	ATP-dependent DNA helicase activity
LZ758_RS02910	COG0358	DNA primase activity
LZ758_RS02920	COG1610	YqeY-like protein
LZ758_RS02935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ758_RS02940	COG0668	transmembrane transport
LZ758_RS02960	COG1183	phosphatidylcholine synthase activity
LZ758_RS02990	COG0604	alcohol dehydrogenase
LZ758_RS02995	COG0330	HflC and HflK could
LZ758_RS03000	COG0330	HflC and HflK could
LZ758_RS03015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ758_RS03045	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ758_RS03055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ758_RS03060	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ758_RS03065	COG1611	Belongs to the LOG family
LZ758_RS03110	COG0827	DNA restriction-modification system
LZ758_RS03115	COG0827	DNA restriction-modification system
LZ758_RS03140	COG0629	single-stranded DNA binding
LZ758_RS03235	COG2878	Part of a membrane complex involved in electron transport
LZ758_RS03255	COG3107	peptidoglycan biosynthetic process
LZ758_RS03270	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ758_RS03285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ758_RS03285	COG0519	Catalyzes the synthesis of GMP from XMP
LZ758_RS03345	COG3590	peptidase
LZ758_RS03370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ758_RS03390	COG0628	permease
LZ758_RS03400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ758_RS03405	COG3178	'Phosphotransferase
LZ758_RS03410	COG1555	photosystem II stabilization
LZ758_RS03415	COG1477	protein flavinylation
LZ758_RS03440	COG4774	siderophore transport
LZ758_RS03460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ758_RS03475	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ758_RS03480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ758_RS03485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ758_RS03520	COG1324	tolerance protein
LZ758_RS03530	COG0352	thiamine-phosphate diphosphorylase activity
LZ758_RS03530	COG0351	phosphomethylpyrimidine kinase
LZ758_RS03585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ758_RS03600	COG2311	Membrane
LZ758_RS03610	COG0791	NLP P60 protein
LZ758_RS03615	COG0791	NLP P60 protein
LZ758_RS03625	COG1301	dicarboxylic acid transport
LZ758_RS03645	COG0037	tRNA processing
LZ758_RS03655	COG0142	geranyltranstransferase activity
LZ758_RS03700	COG1028	Short-chain dehydrogenase reductase Sdr
LZ758_RS03715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ758_RS03720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ758_RS03755	COG1509	lysine 2,3-aminomutase activity
LZ758_RS03765	COG0402	S-adenosylhomocysteine deaminase activity
LZ758_RS03815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ758_RS03825	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZ758_RS03850	COG0436	Aminotransferase
LZ758_RS03895	COG1175	transmembrane transport
LZ758_RS03900	COG0395	ABC-type sugar transport system, permease component
LZ758_RS03955	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ758_RS03970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ758_RS04000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZ758_RS04020	COG0268	Binds directly to 16S ribosomal RNA
LZ758_RS04025	COG0728	peptidoglycan biosynthetic process
LZ758_RS04030	COG0196	riboflavin kinase activity
LZ758_RS04085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ758_RS04085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LZ758_RS04145	COG0436	Aminotransferase
LZ758_RS04155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ758_RS04170	COG1064	alcohol dehydrogenase
LZ758_RS04185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ758_RS04190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ758_RS04250	COG0438	transferase activity, transferring glycosyl groups
LZ758_RS04260	COG0438	transferase activity, transferring glycosyl groups
LZ758_RS04265	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ758_RS04280	COG2954	triphosphatase activity
LZ758_RS04290	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ758_RS04300	COG1278	Cold shock
LZ758_RS04325	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ758_RS04360	COG1605	Chorismate mutase
LZ758_RS04360	COG0287	Prephenate dehydrogenase
LZ758_RS04370	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ758_RS04395	COG4555	ABC transporter
LZ758_RS04400	COG1668	transmembrane transport
LZ758_RS04410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZ758_RS04415	COG1605	Chorismate mutase
LZ758_RS04415	COG0077	Prephenate dehydratase
LZ758_RS04520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ758_RS04530	COG0489	protein tyrosine kinase activity
LZ758_RS04575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZ758_RS04640	COG1192	Involved in chromosome partitioning
LZ758_RS04655	COG0463	Glycosyl transferase, family 2
LZ758_RS04665	COG0318	PFAM AMP-dependent synthetase and ligase
LZ758_RS04670	COG1335	isochorismatase
LZ758_RS04675	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ758_RS04685	COG0676	glucose-6-phosphate 1-epimerase activity
LZ758_RS04715	COG1297	OPT oligopeptide transporter protein
LZ758_RS04720	COG0823	Involved in the tonB-independent uptake of proteins
LZ758_RS04720	COG1506	peptidase
LZ758_RS04725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ758_RS04790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ758_RS04820	COG4953	penicillin-binding protein 1C
LZ758_RS04845	COG1686	Belongs to the peptidase S11 family
LZ758_RS04860	COG0540	Belongs to the ATCase OTCase family
LZ758_RS04865	COG0527	aspartate kinase activity
LZ758_RS04865	COG0460	homoserine dehydrogenase
LZ758_RS04935	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LZ758_RS04945	COG0531	amino acid
LZ758_RS04950	COG0531	amino acid
LZ758_RS04955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ758_RS04960	COG0277	FAD linked oxidase domain protein
LZ758_RS05060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZ758_RS05065	COG2951	lytic endotransglycosylase activity
LZ758_RS05105	COG3118	belongs to the thioredoxin family
LZ758_RS05110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ758_RS05125	COG2183	response to ionizing radiation
LZ758_RS05150	COG0328	RNA-DNA hybrid ribonuclease activity
LZ758_RS05155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ758_RS05160	COG0631	protein serine/threonine phosphatase activity
LZ758_RS05175	COG0859	PFAM glycosyl transferase family 9
LZ758_RS05235	COG4651	solute:proton antiporter activity
LZ758_RS05235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ758_RS05255	COG0488	(ABC) transporter
LZ758_RS05260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ758_RS05305	COG0675	Transposase, IS605 OrfB family
LZ758_RS05420	COG1131	(ABC) transporter
LZ758_RS05425	COG0386	Belongs to the glutathione peroxidase family
LZ758_RS05465	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ758_RS05470	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ758_RS05490	COG2226	methyltransferase
LZ758_RS05510	COG0400	carboxylic ester hydrolase activity
LZ758_RS05515	COG3275	phosphorelay sensor kinase activity
LZ758_RS05560	COG0463	Glycosyl transferase, family 2
LZ758_RS05570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ758_RS05580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ758_RS05580	COG0392	lysyltransferase activity
LZ758_RS05585	COG0251	oxidation-reduction process
LZ758_RS05600	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ758_RS05615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ758_RS05680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LZ758_RS05680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LZ758_RS05705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ758_RS05765	COG0537	adenosine 5'-monophosphoramidase activity
LZ758_RS05785	COG0714	Associated with various cellular activities
LZ758_RS05795	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ758_RS05805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ758_RS05840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ758_RS05845	COG1764	response to oxidative stress
LZ758_RS05850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ758_RS05910	COG2353	YceI-like domain
LZ758_RS05915	COG1968	undecaprenyl-diphosphatase activity
LZ758_RS05920	COG0174	glutamine synthetase
LZ758_RS05925	COG0347	Belongs to the P(II) protein family
LZ758_RS05930	COG0004	ammonium transporteR
LZ758_RS05945	COG2204	response regulator
LZ758_RS05950	COG3852	Histidine kinase
LZ758_RS05965	COG0675	Transposase, IS605 OrfB family
LZ758_RS06170	COG0406	alpha-ribazole phosphatase activity
LZ758_RS06190	COG0386	Belongs to the glutathione peroxidase family
LZ758_RS06210	COG0602	queuosine metabolic process
LZ758_RS06220	COG2885	chlorophyll binding
LZ758_RS06245	COG0824	Thioesterase
LZ758_RS06290	COG0552	protein localization to endoplasmic reticulum
LZ758_RS06305	COG0084	hydrolase, TatD family'
LZ758_RS06355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ758_RS06390	COG2091	lysine biosynthetic process via aminoadipic acid
LZ758_RS06400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ758_RS06405	COG1301	dicarboxylic acid transport
LZ758_RS06425	COG0339	signal peptide processing
LZ758_RS06435	COG0285	dihydrofolate synthase activity
LZ758_RS06465	COG0643	Histidine kinase
LZ758_RS06465	COG0784	Response regulator, receiver
LZ758_RS06465	COG2198	Histidine kinase
LZ758_RS06470	COG0840	transmembrane signaling receptor activity
LZ758_RS06515	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ758_RS06520	COG0596	Alpha beta hydrolase
LZ758_RS06540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ758_RS06550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ758_RS06570	COG1289	transmembrane transporter activity
LZ758_RS06575	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ758_RS06590	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ758_RS06595	COG0582	viral genome integration into host DNA
LZ758_RS06605	COG0557	exoribonuclease II activity
LZ758_RS06615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ758_RS06655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ758_RS06690	COG0778	Nitroreductase
LZ758_RS06700	COG0006	proline dipeptidase activity
LZ758_RS06725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ758_RS06745	COG0025	NhaP-type Na H and K H
LZ758_RS06755	COG2925	Exonuclease
LZ758_RS06785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZ758_RS06795	COG3609	addiction module antidote protein, CC2985 family
LZ758_RS06815	COG3657	addiction module killer protein
LZ758_RS06835	COG0675	Transposase, IS605 OrfB family
LZ758_RS06880	COG3451	type IV secretory pathway VirB4
LZ758_RS06930	COG2902	Dehydrogenase
LZ758_RS06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ758_RS06940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ758_RS07045	COG2850	peptidyl-arginine hydroxylation
LZ758_RS07050	COG0567	Dehydrogenase, E1 component
LZ758_RS07075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ758_RS07140	COG0583	DNA-binding transcription factor activity
LZ758_RS07145	COG3634	alkyl hydroperoxide reductase activity
LZ758_RS07160	COG1450	Type ii and iii secretion system protein
LZ758_RS07175	COG3166	PFAM Fimbrial assembly family protein
LZ758_RS07180	COG3156	type II secretion system protein K
LZ758_RS07185	COG4795	General secretion pathway protein
LZ758_RS07190	COG2165	general secretion pathway protein
LZ758_RS07195	COG4970	Tfp pilus assembly protein FimT
LZ758_RS07200	COG2165	general secretion pathway protein
LZ758_RS07205	COG1459	type II secretion system
LZ758_RS07210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ758_RS07215	COG5295	Hep Hag repeat protein
LZ758_RS07260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ758_RS07275	COG1561	YicC-like family, N-terminal region
LZ758_RS07285	COG1758	RNA polymerase activity
LZ758_RS07300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ758_RS07355	COG0308	aminopeptidase N
LZ758_RS07395	COG3617	BRO family, N-terminal domain
LZ758_RS07500	COG3617	BRO family, N-terminal domain
LZ758_RS07520	COG3772	lysozyme
LZ758_RS07705	COG1959	2 iron, 2 sulfur cluster binding
LZ758_RS07710	COG0719	Fe-S assembly protein
LZ758_RS07715	COG0396	ATPase activity
LZ758_RS07720	COG0719	Fe-S assembly protein
LZ758_RS07740	COG0297	glycogen (starch) synthase activity
LZ758_RS07745	COG0726	polysaccharide deacetylase
LZ758_RS07750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ758_RS07755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ758_RS07760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ758_RS07765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ758_RS07770	COG1609	Transcriptional regulator
LZ758_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
LZ758_RS07805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ758_RS07810	COG4191	Histidine kinase
LZ758_RS07820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ758_RS07840	COG0492	ferredoxin-NADP+ reductase activity
LZ758_RS07860	COG0542	response to heat
LZ758_RS07890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ758_RS07910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LZ758_RS07925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ758_RS07935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ758_RS07980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ758_RS07995	COG1137	ATPase activity
LZ758_RS08030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ758_RS08065	COG0142	geranyltranstransferase activity
LZ758_RS08070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ758_RS08075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ758_RS08080	COG1845	cytochrome c oxidase, subunit III
LZ758_RS08085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ758_RS08155	COG3093	addiction module antidote protein HigA
LZ758_RS08165	COG2944	sequence-specific DNA binding
LZ758_RS08245	COG3772	lysozyme
LZ758_RS08285	COG4197	protein conserved in bacteria, prophage-related
LZ758_RS08335	COG3617	BRO family, N-terminal domain
LZ758_RS08380	COG1643	Atp-dependent helicase
LZ758_RS08385	COG0783	Belongs to the Dps family
LZ758_RS08390	COG0514	ATP-dependent DNA helicase (RecQ)
LZ758_RS08400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ758_RS08435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ758_RS08460	COG0741	lytic transglycosylase activity
LZ758_RS08470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZ758_RS08495	COG1846	Transcriptional regulator
LZ758_RS08520	COG4208	sulfate ABC transporter
LZ758_RS08525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ758_RS08590	COG2353	YceI-like domain
LZ758_RS08605	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ758_RS08625	COG2894	cell division
LZ758_RS08645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ758_RS08655	COG0772	Belongs to the SEDS family
LZ758_RS08660	COG0768	penicillin binding
LZ758_RS08665	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ758_RS08675	COG1077	Cell shape determining protein MreB Mrl
LZ758_RS08715	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ758_RS08720	COG1127	ABC transporter
LZ758_RS08725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ758_RS08725	COG3218	ABC-type transport auxiliary lipoprotein component
LZ758_RS08740	COG0644	oxidoreductase
LZ758_RS08740	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ758_RS08750	COG2840	Smr protein MutS2
LZ758_RS08805	COG1253	flavin adenine dinucleotide binding
LZ758_RS08810	COG2733	membrane
LZ758_RS08840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZ758_RS08845	COG5297	Belongs to the glycosyl hydrolase family 6
LZ758_RS08875	COG0668	transmembrane transport
LZ758_RS09045	COG0582	viral genome integration into host DNA
LZ758_RS09055	COG2911	Protein conserved in bacteria
LZ758_RS09060	COG0729	surface antigen
LZ758_RS09070	COG1956	GAF domain-containing protein
LZ758_RS09080	COG1643	Atp-dependent helicase
LZ758_RS09100	COG1131	(ABC) transporter
LZ758_RS09105	COG0842	Transport permease protein
LZ758_RS09145	COG1217	gtp-binding protein TYPA
LZ758_RS09150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ758_RS09160	COG0625	glutathione transferase activity
LZ758_RS09165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ758_RS09185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZ758_RS09190	COG1187	pseudouridine synthase activity
LZ758_RS09205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ758_RS09210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ758_RS09245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZ758_RS09270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ758_RS09280	COG5380	lipid catabolic process
LZ758_RS09290	COG0606	chelatase, subunit chli
LZ758_RS09295	COG2960	long-chain fatty acid transporting porin activity
LZ758_RS09325	COG0201	protein transport
LZ758_RS09440	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ758_RS09500	COG1064	alcohol dehydrogenase
LZ758_RS09515	COG0583	DNA-binding transcription factor activity
LZ758_RS09520	COG0312	modulator of DNA gyrase
LZ758_RS09530	COG0312	modulator of DNA gyrase
LZ758_RS09555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ758_RS09560	COG0494	nUDIX hydrolase
LZ758_RS09580	COG0527	aspartate kinase activity
LZ758_RS09585	COG1024	Enoyl-CoA hydratase
LZ758_RS09610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ758_RS09680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ758_RS09700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ758_RS09770	COG3077	Addiction module antitoxin, RelB DinJ family
LZ758_RS09815	COG0811	peptide transport
LZ758_RS09845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ758_RS09855	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ758_RS09860	COG2009	succinate dehydrogenase
LZ758_RS09870	COG0354	folic acid binding
LZ758_RS09900	COG0800	Aldolase
LZ758_RS09930	COG0528	UMP kinase activity
LZ758_RS09945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ758_RS09975	COG3617	BRO family, N-terminal domain
LZ758_RS10050	COG3617	BRO family, N-terminal domain
LZ758_RS10070	COG3772	lysozyme
LZ758_RS10190	COG0575	Belongs to the CDS family
LZ758_RS10280	COG1946	Acyl-CoA thioesterase
LZ758_RS10295	COG1914	H( )-stimulated, divalent metal cation uptake system
LZ758_RS10385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ758_RS10410	COG2166	iron-sulfur cluster assembly
LZ758_RS10425	COG0288	reversible hydration of carbon dioxide
LZ758_RS10450	COG2011	ABC-type metal ion transport system permease component
LZ758_RS10470	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ758_RS10475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZ758_RS10485	COG0626	cystathionine gamma-synthase activity
LZ758_RS10490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ758_RS10495	COG0739	heme binding
LZ758_RS10510	COG1238	metal cluster binding
LZ758_RS10550	COG1388	LysM domain
LZ758_RS10550	COG3858	chitin binding
LZ758_RS10555	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ758_RS10565	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ758_RS10580	COG3537	Alpha-1,2-mannosidase
LZ758_RS10605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ758_RS10610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ758_RS10655	COG0469	pyruvate kinase activity
LZ758_RS10680	COG0735	belongs to the Fur family
LZ758_RS10690	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ758_RS10690	COG5297	Belongs to the glycosyl hydrolase family 6
LZ758_RS10700	COG0612	Peptidase, M16
LZ758_RS10715	COG4305	rare lipoprotein A
LZ758_RS10725	COG0739	heme binding
LZ758_RS10740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZ758_RS10750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ758_RS10780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ758_RS10795	COG3116	cell division
LZ758_RS10810	COG0471	metal ion transport
LZ758_RS10810	COG3273	potassium ion transport
LZ758_RS10860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ758_RS10920	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ758_RS10925	COG0802	atpase or kinase
LZ758_RS10930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ758_RS10930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ758_RS11010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZ758_RS11035	COG0745	RESPONSE REGULATOR receiver
LZ758_RS11040	COG0642	Histidine kinase
LZ758_RS11050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ758_RS11095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ758_RS11105	COG2831	hemolysin activation secretion protein
LZ758_RS11130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ758_RS11160	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LZ758_RS11170	COG0316	Belongs to the HesB IscA family
LZ758_RS11210	COG0697	spore germination
LZ758_RS11215	COG0671	phosphoesterase, PA-phosphatase related
LZ758_RS11230	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ758_RS11235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZ758_RS11250	COG1132	(ABC) transporter
LZ758_RS11255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ758_RS11260	COG1538	Outer membrane efflux protein
LZ758_RS11290	COG0745	RESPONSE REGULATOR receiver
LZ758_RS11295	COG4783	chaperone-mediated protein folding
LZ758_RS11305	COG0473	3-isopropylmalate dehydrogenase activity
LZ758_RS11315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZ758_RS11320	COG3083	sulfuric ester hydrolase activity
LZ758_RS11325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ758_RS11350	COG0564	pseudouridine synthase activity
LZ758_RS11355	COG1530	ribonuclease E activity
LZ758_RS11360	COG2197	response regulator
LZ758_RS11375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ758_RS11390	COG0488	(ABC) transporter
LZ758_RS11400	COG1278	Cold shock
LZ758_RS11500	COG0012	GTP binding
LZ758_RS11595	COG2095	MarC family integral membrane protein
LZ758_RS11605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ758_RS11630	COG2132	Multicopper oxidase
LZ758_RS11640	COG0210	DNA helicase
LZ758_RS11650	COG0616	signal peptide processing
LZ758_RS11670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ758_RS11685	COG2201	protein-glutamate methylesterase activity
LZ758_RS11690	COG2177	Part of the ABC transporter FtsEX involved in
LZ758_RS11695	COG2884	Cell division ATP-binding protein ftsE
LZ758_RS11705	COG3118	belongs to the thioredoxin family
LZ758_RS11710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ758_RS11730	COG0793	Belongs to the peptidase S41A family
LZ758_RS11735	COG4942	peptidase
LZ758_RS11750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ758_RS11755	COG0493	'glutamate synthase
LZ758_RS11760	COG0067	glutamate synthase
LZ758_RS11760	COG0069	glutamate synthase activity
LZ758_RS11760	COG0070	glutamate synthase
LZ758_RS11810	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ758_RS12020	COG3505	Type IV secretory pathway VirD4
LZ758_RS12040	COG3736	Type IV secretory pathway, component VirB8