locus-tag	class	description
LZ757_RS00010	COG0592	DNA-directed DNA polymerase activity
LZ757_RS00020	COG0187	DNA topoisomerase II activity
LZ757_RS00030	COG0501	Belongs to the peptidase M48B family
LZ757_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ757_RS00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ757_RS00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ757_RS00165	COG0511	ligase activity, forming carbon-carbon bonds
LZ757_RS00170	COG0439	Biotin carboxylase
LZ757_RS00175	COG0210	DNA helicase
LZ757_RS00200	COG1040	competence protein
LZ757_RS00210	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ757_RS00250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ757_RS00260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ757_RS00290	COG3121	Chaperone
LZ757_RS00295	COG3539	Fimbrial protein
LZ757_RS00300	COG1546	Belongs to the CinA family
LZ757_RS00305	COG0477	Major facilitator Superfamily
LZ757_RS00310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ757_RS00325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ757_RS00340	COG1534	Rna-binding protein
LZ757_RS00370	COG1560	Kdo2-lipid A biosynthetic process
LZ757_RS00375	COG1519	Transferase
LZ757_RS00415	COG1393	Belongs to the ArsC family
LZ757_RS00425	COG0367	asparagine synthase
LZ757_RS00435	COG2070	2-Nitropropane dioxygenase
LZ757_RS00450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZ757_RS00465	COG0339	signal peptide processing
LZ757_RS00550	COG4221	oxidoreductase activity
LZ757_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ757_RS00580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ757_RS00635	COG2223	nitrite transmembrane transporter activity
LZ757_RS00645	COG0739	heme binding
LZ757_RS00680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ757_RS00695	COG1028	Short-chain dehydrogenase reductase Sdr
LZ757_RS00705	COG1272	protein, Hemolysin III
LZ757_RS00710	COG0463	Glycosyl transferase, family 2
LZ757_RS00715	COG0084	hydrolase, TatD family'
LZ757_RS00745	COG0330	HflC and HflK could
LZ757_RS00750	COG3956	TIGRFAM MazG family protein
LZ757_RS00755	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZ757_RS00760	COG0494	nUDIX hydrolase
LZ757_RS00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ757_RS00775	COG0513	Belongs to the DEAD box helicase family
LZ757_RS00780	COG0720	synthase
LZ757_RS00805	COG1981	membrane
LZ757_RS00840	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ757_RS00875	COG0006	proline dipeptidase activity
LZ757_RS00895	COG1862	Preprotein translocase
LZ757_RS00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ757_RS00905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ757_RS00915	COG0617	tRNA 3'-terminal CCA addition
LZ757_RS00955	COG0195	Participates in both transcription termination and antitermination
LZ757_RS00985	COG1733	regulation of RNA biosynthetic process
LZ757_RS00990	COG0702	epimerase
LZ757_RS01035	COG2086	electron transfer activity
LZ757_RS01065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ757_RS01095	COG0477	Major facilitator Superfamily
LZ757_RS01115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ757_RS01120	COG0671	phosphoesterase, PA-phosphatase related
LZ757_RS01135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ757_RS01140	COG0628	permease
LZ757_RS01160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ757_RS01165	COG1090	epimerase
LZ757_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
LZ757_RS01190	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ757_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ757_RS01260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ757_RS01280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ757_RS01285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ757_RS01290	COG1034	ATP synthesis coupled electron transport
LZ757_RS01325	COG1007	ATP synthesis coupled electron transport
LZ757_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
LZ757_RS01335	COG2851	Citrate transporter
LZ757_RS01350	COG0642	Histidine kinase
LZ757_RS01365	COG2205	protein histidine kinase activity
LZ757_RS01365	COG0784	Response regulator, receiver
LZ757_RS01385	COG0280	phosphate acetyltransferase
LZ757_RS01385	COG0281	malic enzyme
LZ757_RS01395	COG0742	ribosomal rna small subunit methyltransferase
LZ757_RS01415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ757_RS01435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ757_RS01455	COG1199	ATP-dependent helicase activity
LZ757_RS01465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ757_RS01550	COG0598	Magnesium transport protein CorA
LZ757_RS01560	COG4535	Mg2 and Co2 transporter CorC
LZ757_RS01575	COG1702	phosphate starvation-inducible protein PhoH
LZ757_RS01585	COG0741	lytic transglycosylase activity
LZ757_RS01590	COG0723	plastoquinol--plastocyanin reductase activity
LZ757_RS01595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ757_RS01600	COG2857	Cytochrome c1
LZ757_RS01605	COG0625	glutathione transferase activity
LZ757_RS01610	COG2969	positive regulation of protein catabolic process
LZ757_RS01655	COG0758	DNA mediated transformation
LZ757_RS01680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ757_RS01690	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LZ757_RS01690	COG1918	ferrous iron import across plasma membrane
LZ757_RS01705	COG0564	pseudouridine synthase activity
LZ757_RS01720	COG3011	Protein conserved in bacteria
LZ757_RS01730	COG0488	(ABC) transporter
LZ757_RS01750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ757_RS01750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ757_RS01780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ757_RS01800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ757_RS01845	COG0629	single-stranded DNA binding
LZ757_RS01850	COG3617	BRO family, N-terminal domain
LZ757_RS01865	COG5532	Uncharacterized conserved protein (DUF2303)
LZ757_RS01945	COG3617	BRO family, N-terminal domain
LZ757_RS01950	COG3617	BRO family, N-terminal domain
LZ757_RS01955	COG3617	BRO family, N-terminal domain
LZ757_RS01995	COG3772	lysozyme
LZ757_RS02020	COG5410	chromosome segregation
LZ757_RS02025	COG3567	Phage-associated protein, HI1409 family
LZ757_RS02030	COG0582	viral genome integration into host DNA
LZ757_RS02050	COG2369	cell adhesion
LZ757_RS02115	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ757_RS02120	COG3657	addiction module killer protein
LZ757_RS02155	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ757_RS02160	COG3657	addiction module killer protein
LZ757_RS02240	COG3617	BRO family, N-terminal domain
LZ757_RS02335	COG3617	BRO family, N-terminal domain
LZ757_RS02350	COG0305	Participates in initiation and elongation during chromosome replication
LZ757_RS02375	COG3772	lysozyme
LZ757_RS02400	COG5410	chromosome segregation
LZ757_RS02405	COG3567	Phage-associated protein, HI1409 family
LZ757_RS02410	COG0582	viral genome integration into host DNA
LZ757_RS02435	COG2369	cell adhesion
LZ757_RS02500	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ757_RS02505	COG3657	addiction module killer protein
LZ757_RS02540	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ757_RS02545	COG3657	addiction module killer protein
LZ757_RS02580	COG4206	TonB-dependent receptor
LZ757_RS02595	COG0277	FAD linked oxidase domain protein
LZ757_RS02600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ757_RS02610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ757_RS02635	COG0305	Participates in initiation and elongation during chromosome replication
LZ757_RS02645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ757_RS02650	COG0667	Aldo Keto reductase
LZ757_RS02690	COG2194	sulfuric ester hydrolase activity
LZ757_RS02775	COG2193	ferroxidase activity
LZ757_RS02810	COG0861	Integral membrane protein TerC family
LZ757_RS02815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ757_RS02820	COG0531	amino acid
LZ757_RS02830	COG1116	anion transmembrane transporter activity
LZ757_RS02840	COG2853	Lipoprotein
LZ757_RS02860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ757_RS02865	COG1127	ABC transporter
LZ757_RS02870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ757_RS02875	COG1074	ATP-dependent DNA helicase activity
LZ757_RS02915	COG0358	DNA primase activity
LZ757_RS02925	COG1610	YqeY-like protein
LZ757_RS02940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ757_RS02945	COG0668	transmembrane transport
LZ757_RS02965	COG1183	phosphatidylcholine synthase activity
LZ757_RS02995	COG0604	alcohol dehydrogenase
LZ757_RS03000	COG0330	HflC and HflK could
LZ757_RS03005	COG0330	HflC and HflK could
LZ757_RS03020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ757_RS03050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ757_RS03060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ757_RS03065	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ757_RS03070	COG1611	Belongs to the LOG family
LZ757_RS03115	COG0827	DNA restriction-modification system
LZ757_RS03120	COG0827	DNA restriction-modification system
LZ757_RS03145	COG0629	single-stranded DNA binding
LZ757_RS03240	COG2878	Part of a membrane complex involved in electron transport
LZ757_RS03260	COG3107	peptidoglycan biosynthetic process
LZ757_RS03275	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ757_RS03290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ757_RS03290	COG0519	Catalyzes the synthesis of GMP from XMP
LZ757_RS03385	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ757_RS03405	COG0628	permease
LZ757_RS03415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ757_RS03420	COG3178	'Phosphotransferase
LZ757_RS03425	COG1555	photosystem II stabilization
LZ757_RS03430	COG1477	protein flavinylation
LZ757_RS03455	COG4774	siderophore transport
LZ757_RS03475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ757_RS03490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ757_RS03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ757_RS03500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ757_RS03535	COG1324	tolerance protein
LZ757_RS03545	COG0352	thiamine-phosphate diphosphorylase activity
LZ757_RS03545	COG0351	phosphomethylpyrimidine kinase
LZ757_RS03600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ757_RS03615	COG2311	Membrane
LZ757_RS03625	COG0791	NLP P60 protein
LZ757_RS03630	COG0791	NLP P60 protein
LZ757_RS03640	COG1301	dicarboxylic acid transport
LZ757_RS03655	COG0037	tRNA processing
LZ757_RS03665	COG0142	geranyltranstransferase activity
LZ757_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
LZ757_RS03725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ757_RS03730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ757_RS03765	COG1509	lysine 2,3-aminomutase activity
LZ757_RS03775	COG0402	S-adenosylhomocysteine deaminase activity
LZ757_RS03825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ757_RS03835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZ757_RS03860	COG0436	Aminotransferase
LZ757_RS03905	COG1175	transmembrane transport
LZ757_RS03910	COG0395	ABC-type sugar transport system, permease component
LZ757_RS03965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ757_RS03980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ757_RS04010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZ757_RS04030	COG0268	Binds directly to 16S ribosomal RNA
LZ757_RS04035	COG0728	peptidoglycan biosynthetic process
LZ757_RS04040	COG0196	riboflavin kinase activity
LZ757_RS04095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ757_RS04095	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LZ757_RS04155	COG0436	Aminotransferase
LZ757_RS04165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ757_RS04180	COG1064	alcohol dehydrogenase
LZ757_RS04195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ757_RS04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ757_RS04260	COG0438	transferase activity, transferring glycosyl groups
LZ757_RS04270	COG0438	transferase activity, transferring glycosyl groups
LZ757_RS04275	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ757_RS04290	COG2954	triphosphatase activity
LZ757_RS04300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ757_RS04310	COG1278	Cold shock
LZ757_RS04335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ757_RS04370	COG0287	Prephenate dehydrogenase
LZ757_RS04370	COG1605	Chorismate mutase
LZ757_RS04380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ757_RS04405	COG4555	ABC transporter
LZ757_RS04410	COG1668	transmembrane transport
LZ757_RS04420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZ757_RS04425	COG1605	Chorismate mutase
LZ757_RS04425	COG0077	Prephenate dehydratase
LZ757_RS04525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ757_RS04535	COG0489	protein tyrosine kinase activity
LZ757_RS04580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZ757_RS04645	COG1192	Involved in chromosome partitioning
LZ757_RS04660	COG0463	Glycosyl transferase, family 2
LZ757_RS04670	COG0318	PFAM AMP-dependent synthetase and ligase
LZ757_RS04675	COG1335	isochorismatase
LZ757_RS04680	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ757_RS04690	COG0676	glucose-6-phosphate 1-epimerase activity
LZ757_RS04720	COG1297	OPT oligopeptide transporter protein
LZ757_RS04725	COG1506	peptidase
LZ757_RS04725	COG0823	Involved in the tonB-independent uptake of proteins
LZ757_RS04730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ757_RS04795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ757_RS04825	COG4953	penicillin-binding protein 1C
LZ757_RS04855	COG1686	Belongs to the peptidase S11 family
LZ757_RS04870	COG0540	Belongs to the ATCase OTCase family
LZ757_RS04875	COG0460	homoserine dehydrogenase
LZ757_RS04875	COG0527	aspartate kinase activity
LZ757_RS04945	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LZ757_RS04955	COG0531	amino acid
LZ757_RS04960	COG0531	amino acid
LZ757_RS04965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ757_RS04970	COG0277	FAD linked oxidase domain protein
LZ757_RS05105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZ757_RS05110	COG2951	lytic endotransglycosylase activity
LZ757_RS05155	COG3118	belongs to the thioredoxin family
LZ757_RS05160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ757_RS05175	COG2183	response to ionizing radiation
LZ757_RS05200	COG0328	RNA-DNA hybrid ribonuclease activity
LZ757_RS05205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ757_RS05210	COG0631	protein serine/threonine phosphatase activity
LZ757_RS05225	COG0859	PFAM glycosyl transferase family 9
LZ757_RS05285	COG4651	solute:proton antiporter activity
LZ757_RS05285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ757_RS05305	COG0488	(ABC) transporter
LZ757_RS05310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ757_RS05355	COG0675	Transposase, IS605 OrfB family
LZ757_RS05465	COG1131	(ABC) transporter
LZ757_RS05470	COG0386	Belongs to the glutathione peroxidase family
LZ757_RS05510	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ757_RS05515	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ757_RS05535	COG2226	methyltransferase
LZ757_RS05555	COG0400	carboxylic ester hydrolase activity
LZ757_RS05560	COG3275	phosphorelay sensor kinase activity
LZ757_RS05605	COG0463	Glycosyl transferase, family 2
LZ757_RS05615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ757_RS05625	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ757_RS05625	COG0392	lysyltransferase activity
LZ757_RS05630	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ757_RS05665	COG3617	BRO family, N-terminal domain
LZ757_RS05760	COG3772	lysozyme
LZ757_RS05865	COG0251	oxidation-reduction process
LZ757_RS05880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ757_RS05895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ757_RS05955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LZ757_RS05955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LZ757_RS05980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ757_RS06040	COG0537	adenosine 5'-monophosphoramidase activity
LZ757_RS06060	COG0714	Associated with various cellular activities
LZ757_RS06070	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ757_RS06080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ757_RS06115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ757_RS06120	COG1764	response to oxidative stress
LZ757_RS06125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ757_RS06185	COG2353	YceI-like domain
LZ757_RS06190	COG1968	undecaprenyl-diphosphatase activity
LZ757_RS06195	COG0174	glutamine synthetase
LZ757_RS06200	COG0347	Belongs to the P(II) protein family
LZ757_RS06205	COG0004	ammonium transporteR
LZ757_RS06220	COG2204	response regulator
LZ757_RS06225	COG3852	Histidine kinase
LZ757_RS06240	COG0675	Transposase, IS605 OrfB family
LZ757_RS06340	COG0582	viral genome integration into host DNA
LZ757_RS06455	COG0406	alpha-ribazole phosphatase activity
LZ757_RS06475	COG0386	Belongs to the glutathione peroxidase family
LZ757_RS06495	COG0602	queuosine metabolic process
LZ757_RS06505	COG2885	chlorophyll binding
LZ757_RS06530	COG0824	Thioesterase
LZ757_RS06575	COG0552	protein localization to endoplasmic reticulum
LZ757_RS06590	COG0084	hydrolase, TatD family'
LZ757_RS06640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ757_RS06675	COG2091	lysine biosynthetic process via aminoadipic acid
LZ757_RS06685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ757_RS06690	COG1301	dicarboxylic acid transport
LZ757_RS06710	COG0339	signal peptide processing
LZ757_RS06720	COG0285	dihydrofolate synthase activity
LZ757_RS06750	COG0643	Histidine kinase
LZ757_RS06750	COG2198	Histidine kinase
LZ757_RS06750	COG0784	Response regulator, receiver
LZ757_RS06755	COG0840	transmembrane signaling receptor activity
LZ757_RS06800	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ757_RS06805	COG0596	Alpha beta hydrolase
LZ757_RS06825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ757_RS06835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ757_RS06850	COG1289	transmembrane transporter activity
LZ757_RS06855	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ757_RS06870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ757_RS06875	COG0582	viral genome integration into host DNA
LZ757_RS06885	COG0557	exoribonuclease II activity
LZ757_RS06895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ757_RS06935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ757_RS06970	COG0778	Nitroreductase
LZ757_RS06980	COG0006	proline dipeptidase activity
LZ757_RS07005	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ757_RS07025	COG0025	NhaP-type Na H and K H
LZ757_RS07035	COG2925	Exonuclease
LZ757_RS07065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZ757_RS07075	COG3609	addiction module antidote protein, CC2985 family
LZ757_RS07095	COG3657	addiction module killer protein
LZ757_RS07115	COG0675	Transposase, IS605 OrfB family
LZ757_RS07160	COG3451	type IV secretory pathway VirB4
LZ757_RS07210	COG2902	Dehydrogenase
LZ757_RS07215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ757_RS07220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ757_RS07325	COG2850	peptidyl-arginine hydroxylation
LZ757_RS07330	COG0567	Dehydrogenase, E1 component
LZ757_RS07355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ757_RS07420	COG0583	DNA-binding transcription factor activity
LZ757_RS07425	COG3634	alkyl hydroperoxide reductase activity
LZ757_RS07440	COG1450	Type ii and iii secretion system protein
LZ757_RS07455	COG3166	PFAM Fimbrial assembly family protein
LZ757_RS07460	COG3156	type II secretion system protein K
LZ757_RS07465	COG4795	General secretion pathway protein
LZ757_RS07470	COG2165	general secretion pathway protein
LZ757_RS07475	COG4970	Tfp pilus assembly protein FimT
LZ757_RS07480	COG2165	general secretion pathway protein
LZ757_RS07485	COG1459	type II secretion system
LZ757_RS07490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ757_RS07495	COG5295	Hep Hag repeat protein
LZ757_RS07540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ757_RS07555	COG1561	YicC-like family, N-terminal region
LZ757_RS07565	COG1758	RNA polymerase activity
LZ757_RS07580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ757_RS07635	COG0308	aminopeptidase N
LZ757_RS07675	COG3617	BRO family, N-terminal domain
LZ757_RS07780	COG3617	BRO family, N-terminal domain
LZ757_RS07800	COG3772	lysozyme
LZ757_RS07985	COG1959	2 iron, 2 sulfur cluster binding
LZ757_RS07990	COG0719	Fe-S assembly protein
LZ757_RS07995	COG0396	ATPase activity
LZ757_RS08000	COG0719	Fe-S assembly protein
LZ757_RS08020	COG0297	glycogen (starch) synthase activity
LZ757_RS08025	COG0726	polysaccharide deacetylase
LZ757_RS08030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ757_RS08035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ757_RS08040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ757_RS08045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ757_RS08050	COG1609	Transcriptional regulator
LZ757_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
LZ757_RS08085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ757_RS08090	COG4191	Histidine kinase
LZ757_RS08100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ757_RS08120	COG0492	ferredoxin-NADP+ reductase activity
LZ757_RS08140	COG0542	response to heat
LZ757_RS08170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ757_RS08190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LZ757_RS08205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ757_RS08215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ757_RS08260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ757_RS08275	COG1137	ATPase activity
LZ757_RS08310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ757_RS08345	COG0142	geranyltranstransferase activity
LZ757_RS08350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ757_RS08355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ757_RS08360	COG1845	cytochrome c oxidase, subunit III
LZ757_RS08365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ757_RS08430	COG3093	addiction module antidote protein HigA
LZ757_RS08440	COG2944	sequence-specific DNA binding
LZ757_RS08510	COG3772	lysozyme
LZ757_RS08550	COG4197	protein conserved in bacteria, prophage-related
LZ757_RS08600	COG3617	BRO family, N-terminal domain
LZ757_RS08645	COG1643	Atp-dependent helicase
LZ757_RS08650	COG0783	Belongs to the Dps family
LZ757_RS08655	COG0514	ATP-dependent DNA helicase (RecQ)
LZ757_RS08665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ757_RS08700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ757_RS08725	COG0741	lytic transglycosylase activity
LZ757_RS08735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZ757_RS08760	COG1846	Transcriptional regulator
LZ757_RS08785	COG4208	sulfate ABC transporter
LZ757_RS08790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ757_RS08855	COG2353	YceI-like domain
LZ757_RS08870	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ757_RS08890	COG2894	cell division
LZ757_RS08910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ757_RS08920	COG0772	Belongs to the SEDS family
LZ757_RS08925	COG0768	penicillin binding
LZ757_RS08930	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ757_RS08940	COG1077	Cell shape determining protein MreB Mrl
LZ757_RS08980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ757_RS08985	COG1127	ABC transporter
LZ757_RS08990	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ757_RS08990	COG3218	ABC-type transport auxiliary lipoprotein component
LZ757_RS09005	COG0644	oxidoreductase
LZ757_RS09005	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ757_RS09070	COG1253	flavin adenine dinucleotide binding
LZ757_RS09075	COG2733	membrane
LZ757_RS09105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZ757_RS09110	COG5297	Belongs to the glycosyl hydrolase family 6
LZ757_RS09140	COG0668	transmembrane transport
LZ757_RS09250	COG2911	Protein conserved in bacteria
LZ757_RS09255	COG0729	surface antigen
LZ757_RS09265	COG1956	GAF domain-containing protein
LZ757_RS09275	COG1643	Atp-dependent helicase
LZ757_RS09295	COG1131	(ABC) transporter
LZ757_RS09300	COG0842	Transport permease protein
LZ757_RS09340	COG1217	gtp-binding protein TYPA
LZ757_RS09345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ757_RS09355	COG0625	glutathione transferase activity
LZ757_RS09360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ757_RS09380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZ757_RS09385	COG1187	pseudouridine synthase activity
LZ757_RS09400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ757_RS09405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ757_RS09440	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZ757_RS09465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ757_RS09475	COG5380	lipid catabolic process
LZ757_RS09490	COG0606	chelatase, subunit chli
LZ757_RS09495	COG2960	long-chain fatty acid transporting porin activity
LZ757_RS09525	COG0201	protein transport
LZ757_RS09640	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ757_RS09700	COG1064	alcohol dehydrogenase
LZ757_RS09715	COG0583	DNA-binding transcription factor activity
LZ757_RS09720	COG0312	modulator of DNA gyrase
LZ757_RS09730	COG0312	modulator of DNA gyrase
LZ757_RS09755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ757_RS09760	COG0494	nUDIX hydrolase
LZ757_RS09780	COG0527	aspartate kinase activity
LZ757_RS09785	COG1024	Enoyl-CoA hydratase
LZ757_RS09810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ757_RS09880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ757_RS09900	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ757_RS09970	COG3077	Addiction module antitoxin, RelB DinJ family
LZ757_RS10015	COG0811	peptide transport
LZ757_RS10045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ757_RS10055	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ757_RS10060	COG2009	succinate dehydrogenase
LZ757_RS10070	COG0354	folic acid binding
LZ757_RS10100	COG0800	Aldolase
LZ757_RS10130	COG0528	UMP kinase activity
LZ757_RS10165	COG0575	Belongs to the CDS family
LZ757_RS10255	COG1946	Acyl-CoA thioesterase
LZ757_RS10270	COG1914	H( )-stimulated, divalent metal cation uptake system
LZ757_RS10350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ757_RS10375	COG2166	iron-sulfur cluster assembly
LZ757_RS10390	COG0288	reversible hydration of carbon dioxide
LZ757_RS10415	COG2011	ABC-type metal ion transport system permease component
LZ757_RS10435	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ757_RS10440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZ757_RS10455	COG0626	cystathionine gamma-synthase activity
LZ757_RS10460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ757_RS10465	COG0739	heme binding
LZ757_RS10485	COG1238	metal cluster binding
LZ757_RS10525	COG1388	LysM domain
LZ757_RS10525	COG3858	chitin binding
LZ757_RS10530	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ757_RS10540	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ757_RS10555	COG3537	Alpha-1,2-mannosidase
LZ757_RS10580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ757_RS10585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ757_RS10630	COG0469	pyruvate kinase activity
LZ757_RS10655	COG0735	belongs to the Fur family
LZ757_RS10665	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ757_RS10665	COG5297	Belongs to the glycosyl hydrolase family 6
LZ757_RS10675	COG0612	Peptidase, M16
LZ757_RS10690	COG4305	rare lipoprotein A
LZ757_RS10700	COG0739	heme binding
LZ757_RS10715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZ757_RS10725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ757_RS10755	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ757_RS10770	COG3116	cell division
LZ757_RS10785	COG0471	metal ion transport
LZ757_RS10785	COG3273	potassium ion transport
LZ757_RS10835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ757_RS10895	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ757_RS10900	COG0802	atpase or kinase
LZ757_RS10905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ757_RS10905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ757_RS10985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZ757_RS11010	COG0745	RESPONSE REGULATOR receiver
LZ757_RS11015	COG0642	Histidine kinase
LZ757_RS11025	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ757_RS11070	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ757_RS11080	COG2831	hemolysin activation secretion protein
LZ757_RS11105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ757_RS11135	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LZ757_RS11145	COG0316	Belongs to the HesB IscA family
LZ757_RS11185	COG0697	spore germination
LZ757_RS11190	COG0671	phosphoesterase, PA-phosphatase related
LZ757_RS11205	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ757_RS11210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZ757_RS11225	COG1132	(ABC) transporter
LZ757_RS11230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ757_RS11235	COG1538	Outer membrane efflux protein
LZ757_RS11265	COG0745	RESPONSE REGULATOR receiver
LZ757_RS11270	COG4783	chaperone-mediated protein folding
LZ757_RS11280	COG0473	3-isopropylmalate dehydrogenase activity
LZ757_RS11290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZ757_RS11295	COG3083	sulfuric ester hydrolase activity
LZ757_RS11300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ757_RS11325	COG0564	pseudouridine synthase activity
LZ757_RS11330	COG1530	ribonuclease E activity
LZ757_RS11335	COG2197	response regulator
LZ757_RS11350	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ757_RS11365	COG0488	(ABC) transporter
LZ757_RS11375	COG1278	Cold shock
LZ757_RS11480	COG0012	GTP binding
LZ757_RS11575	COG2095	MarC family integral membrane protein
LZ757_RS11585	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ757_RS11610	COG2132	Multicopper oxidase
LZ757_RS11620	COG0210	DNA helicase
LZ757_RS11630	COG0616	signal peptide processing
LZ757_RS11650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ757_RS11665	COG2201	protein-glutamate methylesterase activity
LZ757_RS11670	COG2177	Part of the ABC transporter FtsEX involved in
LZ757_RS11675	COG2884	Cell division ATP-binding protein ftsE
LZ757_RS11685	COG3118	belongs to the thioredoxin family
LZ757_RS11690	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ757_RS11710	COG0793	Belongs to the peptidase S41A family
LZ757_RS11715	COG4942	peptidase
LZ757_RS11730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ757_RS11735	COG0493	'glutamate synthase
LZ757_RS11740	COG0067	glutamate synthase
LZ757_RS11740	COG0069	glutamate synthase activity
LZ757_RS11740	COG0070	glutamate synthase
LZ757_RS11790	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ757_RS11820	COG0732	type I restriction modification DNA specificity domain
LZ757_RS12015	COG3505	Type IV secretory pathway VirD4
LZ757_RS12035	COG3736	Type IV secretory pathway, component VirB8
LZ757_RS12225	COG3210	domain, Protein