locus-tag	class	description
LZ755_RS00010	COG0592	DNA-directed DNA polymerase activity
LZ755_RS00020	COG0187	DNA topoisomerase II activity
LZ755_RS00030	COG0501	Belongs to the peptidase M48B family
LZ755_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ755_RS00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ755_RS00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ755_RS00165	COG0511	ligase activity, forming carbon-carbon bonds
LZ755_RS00170	COG0439	Biotin carboxylase
LZ755_RS00175	COG0210	DNA helicase
LZ755_RS00200	COG1040	competence protein
LZ755_RS00210	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ755_RS00250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ755_RS00260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ755_RS00290	COG3121	Chaperone
LZ755_RS00295	COG3539	Fimbrial protein
LZ755_RS00300	COG1546	Belongs to the CinA family
LZ755_RS00305	COG0477	Major facilitator Superfamily
LZ755_RS00310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ755_RS00325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ755_RS00340	COG1534	Rna-binding protein
LZ755_RS00370	COG1560	Kdo2-lipid A biosynthetic process
LZ755_RS00375	COG1519	Transferase
LZ755_RS00415	COG1393	Belongs to the ArsC family
LZ755_RS00425	COG0367	asparagine synthase
LZ755_RS00435	COG2070	2-Nitropropane dioxygenase
LZ755_RS00450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LZ755_RS00465	COG0339	signal peptide processing
LZ755_RS00550	COG4221	oxidoreductase activity
LZ755_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ755_RS00580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ755_RS00635	COG2223	nitrite transmembrane transporter activity
LZ755_RS00645	COG0739	heme binding
LZ755_RS00680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ755_RS00695	COG1028	Short-chain dehydrogenase reductase Sdr
LZ755_RS00705	COG1272	protein, Hemolysin III
LZ755_RS00710	COG0463	Glycosyl transferase, family 2
LZ755_RS00715	COG0084	hydrolase, TatD family'
LZ755_RS00745	COG0330	HflC and HflK could
LZ755_RS00750	COG3956	TIGRFAM MazG family protein
LZ755_RS00755	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZ755_RS00760	COG0494	nUDIX hydrolase
LZ755_RS00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ755_RS00775	COG0513	Belongs to the DEAD box helicase family
LZ755_RS00780	COG0720	synthase
LZ755_RS00805	COG1981	membrane
LZ755_RS00840	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ755_RS00875	COG0006	proline dipeptidase activity
LZ755_RS00895	COG1862	Preprotein translocase
LZ755_RS00900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ755_RS00905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ755_RS00915	COG0617	tRNA 3'-terminal CCA addition
LZ755_RS00955	COG0195	Participates in both transcription termination and antitermination
LZ755_RS00985	COG1733	regulation of RNA biosynthetic process
LZ755_RS00990	COG0702	epimerase
LZ755_RS01040	COG2086	electron transfer activity
LZ755_RS01070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ755_RS01105	COG0477	Major facilitator Superfamily
LZ755_RS01125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ755_RS01130	COG0671	phosphoesterase, PA-phosphatase related
LZ755_RS01145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ755_RS01150	COG0628	permease
LZ755_RS01170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ755_RS01175	COG1090	epimerase
LZ755_RS01180	COG0318	PFAM AMP-dependent synthetase and ligase
LZ755_RS01200	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ755_RS01245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ755_RS01270	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ755_RS01290	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ755_RS01295	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ755_RS01300	COG1034	ATP synthesis coupled electron transport
LZ755_RS01335	COG1007	ATP synthesis coupled electron transport
LZ755_RS01340	COG1028	Short-chain dehydrogenase reductase Sdr
LZ755_RS01345	COG2851	Citrate transporter
LZ755_RS01360	COG0642	Histidine kinase
LZ755_RS01375	COG2205	protein histidine kinase activity
LZ755_RS01375	COG0784	Response regulator, receiver
LZ755_RS01395	COG0280	phosphate acetyltransferase
LZ755_RS01395	COG0281	malic enzyme
LZ755_RS01405	COG0742	ribosomal rna small subunit methyltransferase
LZ755_RS01425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ755_RS01445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ755_RS01465	COG1199	ATP-dependent helicase activity
LZ755_RS01475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ755_RS01555	COG0598	Magnesium transport protein CorA
LZ755_RS01565	COG4535	Mg2 and Co2 transporter CorC
LZ755_RS01580	COG1702	phosphate starvation-inducible protein PhoH
LZ755_RS01590	COG0741	lytic transglycosylase activity
LZ755_RS01595	COG0723	plastoquinol--plastocyanin reductase activity
LZ755_RS01600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ755_RS01605	COG2857	Cytochrome c1
LZ755_RS01610	COG0625	glutathione transferase activity
LZ755_RS01615	COG2969	positive regulation of protein catabolic process
LZ755_RS01660	COG0758	DNA mediated transformation
LZ755_RS01685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ755_RS01695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LZ755_RS01695	COG1918	ferrous iron import across plasma membrane
LZ755_RS01710	COG0564	pseudouridine synthase activity
LZ755_RS01725	COG3011	Protein conserved in bacteria
LZ755_RS01735	COG0488	(ABC) transporter
LZ755_RS01755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ755_RS01755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ755_RS01785	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ755_RS01805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ755_RS01850	COG0629	single-stranded DNA binding
LZ755_RS01855	COG3617	BRO family, N-terminal domain
LZ755_RS01870	COG5532	Uncharacterized conserved protein (DUF2303)
LZ755_RS01950	COG3617	BRO family, N-terminal domain
LZ755_RS01955	COG3617	BRO family, N-terminal domain
LZ755_RS01960	COG3617	BRO family, N-terminal domain
LZ755_RS02000	COG3772	lysozyme
LZ755_RS02025	COG5410	chromosome segregation
LZ755_RS02030	COG3567	Phage-associated protein, HI1409 family
LZ755_RS02035	COG0582	viral genome integration into host DNA
LZ755_RS02055	COG2369	cell adhesion
LZ755_RS02125	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ755_RS02130	COG3657	addiction module killer protein
LZ755_RS02165	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ755_RS02170	COG3657	addiction module killer protein
LZ755_RS02245	COG3617	BRO family, N-terminal domain
LZ755_RS02340	COG3617	BRO family, N-terminal domain
LZ755_RS02355	COG0305	Participates in initiation and elongation during chromosome replication
LZ755_RS02380	COG3772	lysozyme
LZ755_RS02405	COG5410	chromosome segregation
LZ755_RS02410	COG3567	Phage-associated protein, HI1409 family
LZ755_RS02415	COG0582	viral genome integration into host DNA
LZ755_RS02435	COG2369	cell adhesion
LZ755_RS02505	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ755_RS02510	COG3657	addiction module killer protein
LZ755_RS02545	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ755_RS02550	COG3657	addiction module killer protein
LZ755_RS02585	COG4206	TonB-dependent receptor
LZ755_RS02600	COG0277	FAD linked oxidase domain protein
LZ755_RS02605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ755_RS02615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ755_RS02640	COG0305	Participates in initiation and elongation during chromosome replication
LZ755_RS02650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ755_RS02655	COG0667	Aldo Keto reductase
LZ755_RS02695	COG2194	sulfuric ester hydrolase activity
LZ755_RS02785	COG2193	ferroxidase activity
LZ755_RS02820	COG0861	Integral membrane protein TerC family
LZ755_RS02825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ755_RS02830	COG0531	amino acid
LZ755_RS02840	COG1116	anion transmembrane transporter activity
LZ755_RS02850	COG2853	Lipoprotein
LZ755_RS02870	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ755_RS02875	COG1127	ABC transporter
LZ755_RS02880	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ755_RS02885	COG1074	ATP-dependent DNA helicase activity
LZ755_RS02925	COG0358	DNA primase activity
LZ755_RS02935	COG1610	YqeY-like protein
LZ755_RS02950	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ755_RS02955	COG0668	transmembrane transport
LZ755_RS02975	COG1183	phosphatidylcholine synthase activity
LZ755_RS03005	COG0604	alcohol dehydrogenase
LZ755_RS03010	COG0330	HflC and HflK could
LZ755_RS03015	COG0330	HflC and HflK could
LZ755_RS03030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ755_RS03060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ755_RS03070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ755_RS03075	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ755_RS03080	COG1611	Belongs to the LOG family
LZ755_RS03125	COG0827	DNA restriction-modification system
LZ755_RS03130	COG0827	DNA restriction-modification system
LZ755_RS03155	COG0629	single-stranded DNA binding
LZ755_RS03250	COG2878	Part of a membrane complex involved in electron transport
LZ755_RS03270	COG3107	peptidoglycan biosynthetic process
LZ755_RS03285	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ755_RS03300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ755_RS03300	COG0519	Catalyzes the synthesis of GMP from XMP
LZ755_RS03360	COG3590	peptidase
LZ755_RS03385	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ755_RS03405	COG0628	permease
LZ755_RS03415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ755_RS03420	COG3178	'Phosphotransferase
LZ755_RS03425	COG1555	photosystem II stabilization
LZ755_RS03430	COG1477	protein flavinylation
LZ755_RS03455	COG4774	siderophore transport
LZ755_RS03475	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ755_RS03490	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ755_RS03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ755_RS03500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ755_RS03535	COG1324	tolerance protein
LZ755_RS03545	COG0352	thiamine-phosphate diphosphorylase activity
LZ755_RS03545	COG0351	phosphomethylpyrimidine kinase
LZ755_RS03600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ755_RS03610	COG2311	Membrane
LZ755_RS03620	COG0791	NLP P60 protein
LZ755_RS03625	COG0791	NLP P60 protein
LZ755_RS03635	COG1301	dicarboxylic acid transport
LZ755_RS03650	COG0037	tRNA processing
LZ755_RS03660	COG0142	geranyltranstransferase activity
LZ755_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
LZ755_RS03720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ755_RS03725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ755_RS03760	COG1509	lysine 2,3-aminomutase activity
LZ755_RS03770	COG0402	S-adenosylhomocysteine deaminase activity
LZ755_RS03820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ755_RS03830	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZ755_RS03855	COG0436	Aminotransferase
LZ755_RS03905	COG1175	transmembrane transport
LZ755_RS03910	COG0395	ABC-type sugar transport system, permease component
LZ755_RS03965	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ755_RS03980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ755_RS04010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZ755_RS04030	COG0268	Binds directly to 16S ribosomal RNA
LZ755_RS04035	COG0728	peptidoglycan biosynthetic process
LZ755_RS04040	COG0196	riboflavin kinase activity
LZ755_RS04095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ755_RS04095	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LZ755_RS04155	COG0436	Aminotransferase
LZ755_RS04165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ755_RS04180	COG1064	alcohol dehydrogenase
LZ755_RS04195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ755_RS04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ755_RS04260	COG0438	transferase activity, transferring glycosyl groups
LZ755_RS04270	COG0438	transferase activity, transferring glycosyl groups
LZ755_RS04275	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ755_RS04290	COG2954	triphosphatase activity
LZ755_RS04300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ755_RS04310	COG1278	Cold shock
LZ755_RS04335	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ755_RS04370	COG1605	Chorismate mutase
LZ755_RS04370	COG0287	Prephenate dehydrogenase
LZ755_RS04380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ755_RS04405	COG4555	ABC transporter
LZ755_RS04410	COG1668	transmembrane transport
LZ755_RS04420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZ755_RS04425	COG0077	Prephenate dehydratase
LZ755_RS04425	COG1605	Chorismate mutase
LZ755_RS04525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ755_RS04535	COG0489	protein tyrosine kinase activity
LZ755_RS04580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZ755_RS04645	COG1192	Involved in chromosome partitioning
LZ755_RS04660	COG0463	Glycosyl transferase, family 2
LZ755_RS04670	COG0318	PFAM AMP-dependent synthetase and ligase
LZ755_RS04675	COG1335	isochorismatase
LZ755_RS04680	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ755_RS04690	COG0676	glucose-6-phosphate 1-epimerase activity
LZ755_RS04720	COG1297	OPT oligopeptide transporter protein
LZ755_RS04725	COG0823	Involved in the tonB-independent uptake of proteins
LZ755_RS04725	COG1506	peptidase
LZ755_RS04730	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ755_RS04795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ755_RS04825	COG4953	penicillin-binding protein 1C
LZ755_RS04850	COG1686	Belongs to the peptidase S11 family
LZ755_RS04865	COG0540	Belongs to the ATCase OTCase family
LZ755_RS04870	COG0460	homoserine dehydrogenase
LZ755_RS04870	COG0527	aspartate kinase activity
LZ755_RS04940	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LZ755_RS04950	COG0531	amino acid
LZ755_RS04955	COG0531	amino acid
LZ755_RS04960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ755_RS04965	COG0277	FAD linked oxidase domain protein
LZ755_RS05095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZ755_RS05100	COG2951	lytic endotransglycosylase activity
LZ755_RS05145	COG3118	belongs to the thioredoxin family
LZ755_RS05150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ755_RS05165	COG2183	response to ionizing radiation
LZ755_RS05190	COG0328	RNA-DNA hybrid ribonuclease activity
LZ755_RS05195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ755_RS05200	COG0631	protein serine/threonine phosphatase activity
LZ755_RS05215	COG0859	PFAM glycosyl transferase family 9
LZ755_RS05275	COG4651	solute:proton antiporter activity
LZ755_RS05275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ755_RS05295	COG0488	(ABC) transporter
LZ755_RS05300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ755_RS05345	COG0675	Transposase, IS605 OrfB family
LZ755_RS05460	COG1131	(ABC) transporter
LZ755_RS05465	COG0386	Belongs to the glutathione peroxidase family
LZ755_RS05505	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ755_RS05510	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ755_RS05530	COG2226	methyltransferase
LZ755_RS05550	COG0400	carboxylic ester hydrolase activity
LZ755_RS05555	COG3275	phosphorelay sensor kinase activity
LZ755_RS05600	COG0463	Glycosyl transferase, family 2
LZ755_RS05610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ755_RS05620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ755_RS05620	COG0392	lysyltransferase activity
LZ755_RS05625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ755_RS05660	COG3617	BRO family, N-terminal domain
LZ755_RS05760	COG3772	lysozyme
LZ755_RS05865	COG0251	oxidation-reduction process
LZ755_RS05880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ755_RS05895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ755_RS05960	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LZ755_RS05960	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LZ755_RS05985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ755_RS06045	COG0537	adenosine 5'-monophosphoramidase activity
LZ755_RS06065	COG0714	Associated with various cellular activities
LZ755_RS06075	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ755_RS06085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ755_RS06120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ755_RS06125	COG1764	response to oxidative stress
LZ755_RS06130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ755_RS06190	COG2353	YceI-like domain
LZ755_RS06195	COG1968	undecaprenyl-diphosphatase activity
LZ755_RS06200	COG0174	glutamine synthetase
LZ755_RS06205	COG0347	Belongs to the P(II) protein family
LZ755_RS06210	COG0004	ammonium transporteR
LZ755_RS06225	COG2204	response regulator
LZ755_RS06230	COG3852	Histidine kinase
LZ755_RS06245	COG0675	Transposase, IS605 OrfB family
LZ755_RS06350	COG0582	viral genome integration into host DNA
LZ755_RS06465	COG0406	alpha-ribazole phosphatase activity
LZ755_RS06485	COG0386	Belongs to the glutathione peroxidase family
LZ755_RS06505	COG0602	queuosine metabolic process
LZ755_RS06515	COG2885	chlorophyll binding
LZ755_RS06540	COG0824	Thioesterase
LZ755_RS06585	COG0552	protein localization to endoplasmic reticulum
LZ755_RS06600	COG0084	hydrolase, TatD family'
LZ755_RS06655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ755_RS06690	COG2091	lysine biosynthetic process via aminoadipic acid
LZ755_RS06700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ755_RS06705	COG1301	dicarboxylic acid transport
LZ755_RS06725	COG0339	signal peptide processing
LZ755_RS06735	COG0285	dihydrofolate synthase activity
LZ755_RS06765	COG0643	Histidine kinase
LZ755_RS06765	COG0784	Response regulator, receiver
LZ755_RS06765	COG2198	Histidine kinase
LZ755_RS06770	COG0840	transmembrane signaling receptor activity
LZ755_RS06815	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ755_RS06820	COG0596	Alpha beta hydrolase
LZ755_RS06840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ755_RS06850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ755_RS06865	COG1289	transmembrane transporter activity
LZ755_RS06870	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ755_RS06885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ755_RS06890	COG0582	viral genome integration into host DNA
LZ755_RS06900	COG0557	exoribonuclease II activity
LZ755_RS06910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ755_RS06950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ755_RS06985	COG0778	Nitroreductase
LZ755_RS06995	COG0006	proline dipeptidase activity
LZ755_RS07020	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ755_RS07040	COG0025	NhaP-type Na H and K H
LZ755_RS07050	COG2925	Exonuclease
LZ755_RS07080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZ755_RS07090	COG3609	addiction module antidote protein, CC2985 family
LZ755_RS07110	COG3657	addiction module killer protein
LZ755_RS07130	COG0675	Transposase, IS605 OrfB family
LZ755_RS07175	COG3451	type IV secretory pathway VirB4
LZ755_RS07225	COG2902	Dehydrogenase
LZ755_RS07230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ755_RS07235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ755_RS07340	COG2850	peptidyl-arginine hydroxylation
LZ755_RS07345	COG0567	Dehydrogenase, E1 component
LZ755_RS07370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ755_RS07435	COG0583	DNA-binding transcription factor activity
LZ755_RS07440	COG3634	alkyl hydroperoxide reductase activity
LZ755_RS07455	COG1450	Type ii and iii secretion system protein
LZ755_RS07470	COG3166	PFAM Fimbrial assembly family protein
LZ755_RS07475	COG3156	type II secretion system protein K
LZ755_RS07480	COG4795	General secretion pathway protein
LZ755_RS07485	COG2165	general secretion pathway protein
LZ755_RS07490	COG4970	Tfp pilus assembly protein FimT
LZ755_RS07495	COG2165	general secretion pathway protein
LZ755_RS07500	COG1459	type II secretion system
LZ755_RS07505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ755_RS07510	COG5295	Hep Hag repeat protein
LZ755_RS07555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ755_RS07570	COG1561	YicC-like family, N-terminal region
LZ755_RS07580	COG1758	RNA polymerase activity
LZ755_RS07595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ755_RS07650	COG0308	aminopeptidase N
LZ755_RS07690	COG3617	BRO family, N-terminal domain
LZ755_RS07795	COG3617	BRO family, N-terminal domain
LZ755_RS07815	COG3772	lysozyme
LZ755_RS08005	COG1959	2 iron, 2 sulfur cluster binding
LZ755_RS08010	COG0719	Fe-S assembly protein
LZ755_RS08015	COG0396	ATPase activity
LZ755_RS08020	COG0719	Fe-S assembly protein
LZ755_RS08040	COG0297	glycogen (starch) synthase activity
LZ755_RS08045	COG0726	polysaccharide deacetylase
LZ755_RS08050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ755_RS08055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ755_RS08060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ755_RS08065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ755_RS08070	COG1609	Transcriptional regulator
LZ755_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
LZ755_RS08105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ755_RS08110	COG4191	Histidine kinase
LZ755_RS08120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ755_RS08140	COG0492	ferredoxin-NADP+ reductase activity
LZ755_RS08160	COG0542	response to heat
LZ755_RS08190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ755_RS08210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LZ755_RS08225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ755_RS08235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ755_RS08280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ755_RS08295	COG1137	ATPase activity
LZ755_RS08330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ755_RS08365	COG0142	geranyltranstransferase activity
LZ755_RS08370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ755_RS08375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ755_RS08380	COG1845	cytochrome c oxidase, subunit III
LZ755_RS08385	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ755_RS08450	COG3093	addiction module antidote protein HigA
LZ755_RS08460	COG2944	sequence-specific DNA binding
LZ755_RS08535	COG3772	lysozyme
LZ755_RS08575	COG4197	protein conserved in bacteria, prophage-related
LZ755_RS08625	COG3617	BRO family, N-terminal domain
LZ755_RS08670	COG1643	Atp-dependent helicase
LZ755_RS08675	COG0783	Belongs to the Dps family
LZ755_RS08680	COG0514	ATP-dependent DNA helicase (RecQ)
LZ755_RS08690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ755_RS08725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ755_RS08750	COG0741	lytic transglycosylase activity
LZ755_RS08760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZ755_RS08785	COG1846	Transcriptional regulator
LZ755_RS08810	COG4208	sulfate ABC transporter
LZ755_RS08815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ755_RS08880	COG2353	YceI-like domain
LZ755_RS08895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ755_RS08915	COG2894	cell division
LZ755_RS08935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ755_RS08945	COG0772	Belongs to the SEDS family
LZ755_RS08950	COG0768	penicillin binding
LZ755_RS08955	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ755_RS08965	COG1077	Cell shape determining protein MreB Mrl
LZ755_RS09005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ755_RS09010	COG1127	ABC transporter
LZ755_RS09015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ755_RS09015	COG3218	ABC-type transport auxiliary lipoprotein component
LZ755_RS09030	COG0644	oxidoreductase
LZ755_RS09030	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ755_RS09095	COG1253	flavin adenine dinucleotide binding
LZ755_RS09100	COG2733	membrane
LZ755_RS09130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZ755_RS09135	COG5297	Belongs to the glycosyl hydrolase family 6
LZ755_RS09165	COG0668	transmembrane transport
LZ755_RS09275	COG2911	Protein conserved in bacteria
LZ755_RS09280	COG0729	surface antigen
LZ755_RS09290	COG1956	GAF domain-containing protein
LZ755_RS09300	COG1643	Atp-dependent helicase
LZ755_RS09320	COG1131	(ABC) transporter
LZ755_RS09325	COG0842	Transport permease protein
LZ755_RS09365	COG1217	gtp-binding protein TYPA
LZ755_RS09370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ755_RS09380	COG0625	glutathione transferase activity
LZ755_RS09385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ755_RS09405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZ755_RS09410	COG1187	pseudouridine synthase activity
LZ755_RS09425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ755_RS09430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ755_RS09465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZ755_RS09490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ755_RS09500	COG5380	lipid catabolic process
LZ755_RS09515	COG0606	chelatase, subunit chli
LZ755_RS09520	COG2960	long-chain fatty acid transporting porin activity
LZ755_RS09550	COG0201	protein transport
LZ755_RS09665	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ755_RS09725	COG1064	alcohol dehydrogenase
LZ755_RS09740	COG0583	DNA-binding transcription factor activity
LZ755_RS09745	COG0312	modulator of DNA gyrase
LZ755_RS09755	COG0312	modulator of DNA gyrase
LZ755_RS09780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ755_RS09785	COG0494	nUDIX hydrolase
LZ755_RS09805	COG0527	aspartate kinase activity
LZ755_RS09810	COG1024	Enoyl-CoA hydratase
LZ755_RS09835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ755_RS09905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ755_RS09925	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ755_RS10000	COG3077	Addiction module antitoxin, RelB DinJ family
LZ755_RS10045	COG0811	peptide transport
LZ755_RS10075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ755_RS10085	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ755_RS10090	COG2009	succinate dehydrogenase
LZ755_RS10100	COG0354	folic acid binding
LZ755_RS10130	COG0800	Aldolase
LZ755_RS10160	COG0528	UMP kinase activity
LZ755_RS10195	COG0575	Belongs to the CDS family
LZ755_RS10285	COG1946	Acyl-CoA thioesterase
LZ755_RS10300	COG1914	H( )-stimulated, divalent metal cation uptake system
LZ755_RS10380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ755_RS10405	COG2166	iron-sulfur cluster assembly
LZ755_RS10420	COG0288	reversible hydration of carbon dioxide
LZ755_RS10445	COG2011	ABC-type metal ion transport system permease component
LZ755_RS10465	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ755_RS10470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZ755_RS10485	COG0626	cystathionine gamma-synthase activity
LZ755_RS10490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ755_RS10495	COG0739	heme binding
LZ755_RS10515	COG1238	metal cluster binding
LZ755_RS10555	COG1388	LysM domain
LZ755_RS10555	COG3858	chitin binding
LZ755_RS10560	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ755_RS10570	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ755_RS10585	COG3537	Alpha-1,2-mannosidase
LZ755_RS10610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ755_RS10615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ755_RS10660	COG0469	pyruvate kinase activity
LZ755_RS10685	COG0735	belongs to the Fur family
LZ755_RS10695	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ755_RS10695	COG5297	Belongs to the glycosyl hydrolase family 6
LZ755_RS10705	COG0612	Peptidase, M16
LZ755_RS10725	COG4305	rare lipoprotein A
LZ755_RS10735	COG0739	heme binding
LZ755_RS10750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZ755_RS10760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ755_RS10790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ755_RS10805	COG3116	cell division
LZ755_RS10820	COG0471	metal ion transport
LZ755_RS10820	COG3273	potassium ion transport
LZ755_RS10870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ755_RS10930	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ755_RS10935	COG0802	atpase or kinase
LZ755_RS10940	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ755_RS10940	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ755_RS11020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZ755_RS11045	COG0745	RESPONSE REGULATOR receiver
LZ755_RS11050	COG0642	Histidine kinase
LZ755_RS11060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ755_RS11105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ755_RS11115	COG2831	hemolysin activation secretion protein
LZ755_RS11140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ755_RS11170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LZ755_RS11180	COG0316	Belongs to the HesB IscA family
LZ755_RS11220	COG0697	spore germination
LZ755_RS11225	COG0671	phosphoesterase, PA-phosphatase related
LZ755_RS11240	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ755_RS11245	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZ755_RS11260	COG1132	(ABC) transporter
LZ755_RS11265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ755_RS11270	COG1538	Outer membrane efflux protein
LZ755_RS11300	COG0745	RESPONSE REGULATOR receiver
LZ755_RS11305	COG4783	chaperone-mediated protein folding
LZ755_RS11315	COG0473	3-isopropylmalate dehydrogenase activity
LZ755_RS11325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZ755_RS11330	COG3083	sulfuric ester hydrolase activity
LZ755_RS11335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ755_RS11360	COG0564	pseudouridine synthase activity
LZ755_RS11365	COG1530	ribonuclease E activity
LZ755_RS11370	COG2197	response regulator
LZ755_RS11385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ755_RS11400	COG0488	(ABC) transporter
LZ755_RS11410	COG1278	Cold shock
LZ755_RS11515	COG0012	GTP binding
LZ755_RS11610	COG2095	MarC family integral membrane protein
LZ755_RS11620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ755_RS11645	COG2132	Multicopper oxidase
LZ755_RS11655	COG0210	DNA helicase
LZ755_RS11665	COG0616	signal peptide processing
LZ755_RS11685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ755_RS11700	COG2201	protein-glutamate methylesterase activity
LZ755_RS11705	COG2177	Part of the ABC transporter FtsEX involved in
LZ755_RS11710	COG2884	Cell division ATP-binding protein ftsE
LZ755_RS11720	COG3118	belongs to the thioredoxin family
LZ755_RS11725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ755_RS11745	COG0793	Belongs to the peptidase S41A family
LZ755_RS11750	COG4942	peptidase
LZ755_RS11765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ755_RS11770	COG0493	'glutamate synthase
LZ755_RS11775	COG0067	glutamate synthase
LZ755_RS11775	COG0069	glutamate synthase activity
LZ755_RS11775	COG0070	glutamate synthase
LZ755_RS11825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ755_RS11855	COG0732	type I restriction modification DNA specificity domain
LZ755_RS12055	COG3505	Type IV secretory pathway VirD4
LZ755_RS12075	COG3736	Type IV secretory pathway, component VirB8