locus-tag	class	description
HKJ31_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKJ31_RS00020	COG0187	DNA topoisomerase II activity
HKJ31_RS00030	COG0501	Belongs to the peptidase M48B family
HKJ31_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKJ31_RS00150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HKJ31_RS00160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKJ31_RS00170	COG0511	ligase activity, forming carbon-carbon bonds
HKJ31_RS00175	COG0439	Biotin carboxylase
HKJ31_RS00180	COG0210	DNA helicase
HKJ31_RS00210	COG1752	Esterase of the alpha-beta hydrolase superfamily
HKJ31_RS00250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HKJ31_RS00260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKJ31_RS00285	COG3121	Chaperone
HKJ31_RS00290	COG3539	Fimbrial protein
HKJ31_RS00295	COG1546	Belongs to the CinA family
HKJ31_RS00300	COG0477	Major facilitator Superfamily
HKJ31_RS00305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKJ31_RS00320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKJ31_RS00325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKJ31_RS00335	COG1534	Rna-binding protein
HKJ31_RS00365	COG1560	Kdo2-lipid A biosynthetic process
HKJ31_RS00370	COG1519	Transferase
HKJ31_RS00390	COG0336	Belongs to the RNA methyltransferase TrmD family
HKJ31_RS00410	COG1393	Belongs to the ArsC family
HKJ31_RS00420	COG0367	asparagine synthase
HKJ31_RS00430	COG2070	2-Nitropropane dioxygenase
HKJ31_RS00460	COG0339	signal peptide processing
HKJ31_RS00545	COG4221	oxidoreductase activity
HKJ31_RS00565	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKJ31_RS00575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ31_RS00615	COG2223	nitrite transmembrane transporter activity
HKJ31_RS00625	COG0739	heme binding
HKJ31_RS00660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HKJ31_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ31_RS00685	COG1272	protein, Hemolysin III
HKJ31_RS00690	COG0463	Glycosyl transferase, family 2
HKJ31_RS00695	COG0084	hydrolase, TatD family'
HKJ31_RS00725	COG0330	HflC and HflK could
HKJ31_RS00730	COG3956	TIGRFAM MazG family protein
HKJ31_RS00740	COG0494	nUDIX hydrolase
HKJ31_RS00750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HKJ31_RS00755	COG0513	Belongs to the DEAD box helicase family
HKJ31_RS00760	COG0720	synthase
HKJ31_RS00780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HKJ31_RS00915	COG3772	lysozyme
HKJ31_RS00990	COG3077	Addiction module antitoxin, RelB DinJ family
HKJ31_RS01100	COG0512	Glutamine amidotransferase of anthranilate synthase
HKJ31_RS01130	COG0006	proline dipeptidase activity
HKJ31_RS01150	COG1862	Preprotein translocase
HKJ31_RS01155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKJ31_RS01160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKJ31_RS01170	COG0617	tRNA 3'-terminal CCA addition
HKJ31_RS01210	COG0195	Participates in both transcription termination and antitermination
HKJ31_RS01240	COG1733	regulation of RNA biosynthetic process
HKJ31_RS01245	COG0702	epimerase
HKJ31_RS01295	COG2086	electron transfer activity
HKJ31_RS01325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ31_RS01350	COG0477	Major facilitator Superfamily
HKJ31_RS01370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HKJ31_RS01375	COG0671	phosphoesterase, PA-phosphatase related
HKJ31_RS01390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKJ31_RS01395	COG0628	permease
HKJ31_RS01415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKJ31_RS01420	COG1090	epimerase
HKJ31_RS01425	COG0318	PFAM AMP-dependent synthetase and ligase
HKJ31_RS01445	COG1049	propionate catabolic process, 2-methylcitrate cycle
HKJ31_RS01495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ31_RS01520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKJ31_RS01540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HKJ31_RS01545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HKJ31_RS01550	COG1034	ATP synthesis coupled electron transport
HKJ31_RS01585	COG1007	ATP synthesis coupled electron transport
HKJ31_RS01590	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ31_RS01595	COG2851	Citrate transporter
HKJ31_RS01610	COG0642	Histidine kinase
HKJ31_RS01625	COG0784	Response regulator, receiver
HKJ31_RS01625	COG2205	protein histidine kinase activity
HKJ31_RS01645	COG0281	malic enzyme
HKJ31_RS01645	COG0280	phosphate acetyltransferase
HKJ31_RS01655	COG0742	ribosomal rna small subunit methyltransferase
HKJ31_RS01670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HKJ31_RS01680	COG3706	GGDEF domain
HKJ31_RS01690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HKJ31_RS01715	COG2166	iron-sulfur cluster assembly
HKJ31_RS01745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKJ31_RS01805	COG1914	H( )-stimulated, divalent metal cation uptake system
HKJ31_RS01820	COG1946	Acyl-CoA thioesterase
HKJ31_RS01895	COG0750	zinc metalloprotease
HKJ31_RS01905	COG0575	Belongs to the CDS family
HKJ31_RS01910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKJ31_RS01940	COG0528	UMP kinase activity
HKJ31_RS01985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKJ31_RS01995	COG0354	folic acid binding
HKJ31_RS02005	COG2009	succinate dehydrogenase
HKJ31_RS02010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HKJ31_RS02020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HKJ31_RS02050	COG0811	peptide transport
HKJ31_RS02205	COG3772	lysozyme
HKJ31_RS02285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKJ31_RS02330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKJ31_RS02330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKJ31_RS02360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HKJ31_RS02385	COG1024	Enoyl-CoA hydratase
HKJ31_RS02390	COG0527	aspartate kinase activity
HKJ31_RS02410	COG0494	nUDIX hydrolase
HKJ31_RS02415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HKJ31_RS02425	COG0424	maF-like protein
HKJ31_RS02430	COG1530	ribonuclease E activity
HKJ31_RS02440	COG0312	modulator of DNA gyrase
HKJ31_RS02450	COG0312	modulator of DNA gyrase
HKJ31_RS02455	COG0583	DNA-binding transcription factor activity
HKJ31_RS02470	COG1064	alcohol dehydrogenase
HKJ31_RS02525	COG0356	it plays a direct role in the translocation of protons across the membrane
HKJ31_RS02580	COG0255	Belongs to the universal ribosomal protein uL29 family
HKJ31_RS02640	COG0201	protein transport
HKJ31_RS02670	COG2960	long-chain fatty acid transporting porin activity
HKJ31_RS02675	COG0606	chelatase, subunit chli
HKJ31_RS02695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HKJ31_RS02755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKJ31_RS02760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKJ31_RS02775	COG1187	pseudouridine synthase activity
HKJ31_RS02780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HKJ31_RS02800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKJ31_RS02805	COG0625	glutathione transferase activity
HKJ31_RS02815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKJ31_RS02860	COG0842	Transport permease protein
HKJ31_RS02865	COG1131	(ABC) transporter
HKJ31_RS02885	COG1643	Atp-dependent helicase
HKJ31_RS02900	COG1956	GAF domain-containing protein
HKJ31_RS02910	COG0729	surface antigen
HKJ31_RS02915	COG2911	Protein conserved in bacteria
HKJ31_RS02970	COG3657	addiction module killer protein
HKJ31_RS02975	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ31_RS03075	COG2369	cell adhesion
HKJ31_RS03080	COG3567	Phage-associated protein, HI1409 family
HKJ31_RS03085	COG5410	chromosome segregation
HKJ31_RS03110	COG3772	lysozyme
HKJ31_RS03125	COG0305	Participates in initiation and elongation during chromosome replication
HKJ31_RS03140	COG3617	BRO family, N-terminal domain
HKJ31_RS03145	COG3617	BRO family, N-terminal domain
HKJ31_RS03235	COG5532	Uncharacterized conserved protein (DUF2303)
HKJ31_RS03255	COG0629	single-stranded DNA binding
HKJ31_RS03355	COG0668	transmembrane transport
HKJ31_RS03385	COG5297	Belongs to the glycosyl hydrolase family 6
HKJ31_RS03425	COG2733	membrane
HKJ31_RS03430	COG1253	flavin adenine dinucleotide binding
HKJ31_RS03480	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HKJ31_RS03495	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HKJ31_RS03495	COG0644	oxidoreductase
HKJ31_RS03510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HKJ31_RS03510	COG3218	ABC-type transport auxiliary lipoprotein component
HKJ31_RS03515	COG1127	ABC transporter
HKJ31_RS03520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HKJ31_RS03550	COG0629	single-stranded DNA binding
HKJ31_RS03575	COG4969	Belongs to the N-Me-Phe pilin family
HKJ31_RS03690	COG0675	Transposase, IS605 OrfB family
HKJ31_RS03735	COG1077	Cell shape determining protein MreB Mrl
HKJ31_RS03740	COG1792	Involved in formation and maintenance of cell shape
HKJ31_RS03745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HKJ31_RS03750	COG0768	penicillin binding
HKJ31_RS03755	COG0772	Belongs to the SEDS family
HKJ31_RS03765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKJ31_RS03785	COG2894	cell division
HKJ31_RS03805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKJ31_RS03820	COG2353	YceI-like domain
HKJ31_RS03870	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HKJ31_RS03875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HKJ31_RS03880	COG4208	sulfate ABC transporter
HKJ31_RS03905	COG1846	Transcriptional regulator
HKJ31_RS03935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HKJ31_RS03945	COG0741	lytic transglycosylase activity
HKJ31_RS03975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKJ31_RS04010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKJ31_RS04020	COG0514	ATP-dependent DNA helicase (RecQ)
HKJ31_RS04025	COG0783	Belongs to the Dps family
HKJ31_RS04030	COG1643	Atp-dependent helicase
HKJ31_RS04040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HKJ31_RS04045	COG1845	cytochrome c oxidase, subunit III
HKJ31_RS04050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKJ31_RS04055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HKJ31_RS04060	COG0142	geranyltranstransferase activity
HKJ31_RS04065	COG0629	single-stranded DNA binding
HKJ31_RS04105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKJ31_RS04140	COG1137	ATPase activity
HKJ31_RS04155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HKJ31_RS04165	COG0271	Belongs to the BolA IbaG family
HKJ31_RS04200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKJ31_RS04210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKJ31_RS04225	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HKJ31_RS04245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKJ31_RS04275	COG0542	response to heat
HKJ31_RS04295	COG0492	ferredoxin-NADP+ reductase activity
HKJ31_RS04315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HKJ31_RS04325	COG4191	Histidine kinase
HKJ31_RS04330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKJ31_RS04335	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ31_RS04365	COG1609	Transcriptional regulator
HKJ31_RS04370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HKJ31_RS04375	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKJ31_RS04380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKJ31_RS04385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ31_RS04390	COG0726	polysaccharide deacetylase
HKJ31_RS04395	COG0297	glycogen (starch) synthase activity
HKJ31_RS04415	COG0719	Fe-S assembly protein
HKJ31_RS04420	COG0396	ATPase activity
HKJ31_RS04425	COG0719	Fe-S assembly protein
HKJ31_RS04430	COG1959	2 iron, 2 sulfur cluster binding
HKJ31_RS04485	COG0308	aminopeptidase N
HKJ31_RS04530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKJ31_RS04555	COG1561	YicC-like family, N-terminal region
HKJ31_RS04570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HKJ31_RS04610	COG5295	Hep Hag repeat protein
HKJ31_RS04615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKJ31_RS04620	COG1459	type II secretion system
HKJ31_RS04625	COG2165	general secretion pathway protein
HKJ31_RS04630	COG4970	Tfp pilus assembly protein FimT
HKJ31_RS04635	COG2165	general secretion pathway protein
HKJ31_RS04640	COG4795	General secretion pathway protein
HKJ31_RS04645	COG3156	type II secretion system protein K
HKJ31_RS04650	COG3166	PFAM Fimbrial assembly family protein
HKJ31_RS04665	COG1450	Type ii and iii secretion system protein
HKJ31_RS04685	COG3634	alkyl hydroperoxide reductase activity
HKJ31_RS04690	COG0583	DNA-binding transcription factor activity
HKJ31_RS04775	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKJ31_RS04780	COG0567	Dehydrogenase, E1 component
HKJ31_RS04785	COG2850	peptidyl-arginine hydroxylation
HKJ31_RS04895	COG3772	lysozyme
HKJ31_RS04990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKJ31_RS04995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ31_RS05000	COG2902	Dehydrogenase
HKJ31_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ31_RS05090	COG2925	Exonuclease
HKJ31_RS05100	COG0025	NhaP-type Na H and K H
HKJ31_RS05120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKJ31_RS05145	COG0006	proline dipeptidase activity
HKJ31_RS05155	COG0778	Nitroreductase
HKJ31_RS05190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKJ31_RS05225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKJ31_RS05240	COG0557	exoribonuclease II activity
HKJ31_RS05250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKJ31_RS05265	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKJ31_RS05270	COG1289	transmembrane transporter activity
HKJ31_RS05305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKJ31_RS05320	COG0596	Alpha beta hydrolase
HKJ31_RS05325	COG0727	PFAM Uncharacterised protein family (UPF0153)
HKJ31_RS05330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HKJ31_RS05330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKJ31_RS05370	COG0840	transmembrane signaling receptor activity
HKJ31_RS05375	COG2198	Histidine kinase
HKJ31_RS05375	COG0643	Histidine kinase
HKJ31_RS05375	COG0784	Response regulator, receiver
HKJ31_RS05405	COG0285	dihydrofolate synthase activity
HKJ31_RS05415	COG0339	signal peptide processing
HKJ31_RS05440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKJ31_RS05450	COG2091	lysine biosynthetic process via aminoadipic acid
HKJ31_RS05490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKJ31_RS05515	COG0084	hydrolase, TatD family'
HKJ31_RS05530	COG0552	protein localization to endoplasmic reticulum
HKJ31_RS05575	COG0824	Thioesterase
HKJ31_RS05600	COG2885	chlorophyll binding
HKJ31_RS05610	COG0602	queuosine metabolic process
HKJ31_RS05625	COG3104	oligopeptide transport
HKJ31_RS05630	COG0386	Belongs to the glutathione peroxidase family
HKJ31_RS05650	COG0406	alpha-ribazole phosphatase activity
HKJ31_RS05715	COG0582	viral genome integration into host DNA
HKJ31_RS05840	COG3852	Histidine kinase
HKJ31_RS05845	COG2204	response regulator
HKJ31_RS05860	COG0004	ammonium transporteR
HKJ31_RS05865	COG0347	Belongs to the P(II) protein family
HKJ31_RS05870	COG0174	glutamine synthetase
HKJ31_RS05875	COG1968	undecaprenyl-diphosphatase activity
HKJ31_RS05880	COG2353	YceI-like domain
HKJ31_RS05935	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HKJ31_RS05940	COG1764	response to oxidative stress
HKJ31_RS05945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ31_RS05955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKJ31_RS05980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKJ31_RS05990	COG1399	metal-binding, possibly nucleic acid-binding protein
HKJ31_RS06000	COG0714	Associated with various cellular activities
HKJ31_RS06020	COG0537	adenosine 5'-monophosphoramidase activity
HKJ31_RS06075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKJ31_RS06105	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKJ31_RS06125	COG4969	Belongs to the N-Me-Phe pilin family
HKJ31_RS06140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKJ31_RS06145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKJ31_RS06155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKJ31_RS06170	COG0251	oxidation-reduction process
HKJ31_RS06175	COG0392	lysyltransferase activity
HKJ31_RS06175	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKJ31_RS06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HKJ31_RS06195	COG0463	Glycosyl transferase, family 2
HKJ31_RS06240	COG3275	phosphorelay sensor kinase activity
HKJ31_RS06245	COG0400	carboxylic ester hydrolase activity
HKJ31_RS06265	COG2226	methyltransferase
HKJ31_RS06280	COG2027	D-alanyl-D-alanine carboxypeptidase
HKJ31_RS06285	COG2027	D-alanyl-D-alanine carboxypeptidase
HKJ31_RS06295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKJ31_RS06335	COG1131	(ABC) transporter
HKJ31_RS06390	COG3657	addiction module killer protein
HKJ31_RS06395	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ31_RS06495	COG2369	cell adhesion
HKJ31_RS06500	COG3567	Phage-associated protein, HI1409 family
HKJ31_RS06505	COG5410	chromosome segregation
HKJ31_RS06530	COG3772	lysozyme
HKJ31_RS06595	COG0489	protein tyrosine kinase activity
HKJ31_RS06605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKJ31_RS06665	COG0488	(ABC) transporter
HKJ31_RS06685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HKJ31_RS06685	COG4651	solute:proton antiporter activity
HKJ31_RS06745	COG0859	PFAM glycosyl transferase family 9
HKJ31_RS06760	COG0631	protein serine/threonine phosphatase activity
HKJ31_RS06765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKJ31_RS06770	COG0328	RNA-DNA hybrid ribonuclease activity
HKJ31_RS06795	COG2183	response to ionizing radiation
HKJ31_RS06810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HKJ31_RS06815	COG3118	belongs to the thioredoxin family
HKJ31_RS06860	COG2951	lytic endotransglycosylase activity
HKJ31_RS06865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKJ31_RS06965	COG0277	FAD linked oxidase domain protein
HKJ31_RS06970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HKJ31_RS06975	COG0531	amino acid
HKJ31_RS06980	COG0531	amino acid
HKJ31_RS07065	COG0527	aspartate kinase activity
HKJ31_RS07065	COG0460	homoserine dehydrogenase
HKJ31_RS07070	COG0540	Belongs to the ATCase OTCase family
HKJ31_RS07085	COG1686	Belongs to the peptidase S11 family
HKJ31_RS07110	COG4953	penicillin-binding protein 1C
HKJ31_RS07130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKJ31_RS07200	COG1506	peptidase
HKJ31_RS07200	COG0823	Involved in the tonB-independent uptake of proteins
HKJ31_RS07205	COG1297	OPT oligopeptide transporter protein
HKJ31_RS07235	COG0676	glucose-6-phosphate 1-epimerase activity
HKJ31_RS07245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKJ31_RS07250	COG1335	isochorismatase
HKJ31_RS07255	COG0318	PFAM AMP-dependent synthetase and ligase
HKJ31_RS07265	COG0463	Glycosyl transferase, family 2
HKJ31_RS07280	COG1192	Involved in chromosome partitioning
HKJ31_RS07395	COG1605	Chorismate mutase
HKJ31_RS07395	COG0077	Prephenate dehydratase
HKJ31_RS07410	COG1668	transmembrane transport
HKJ31_RS07415	COG4555	ABC transporter
HKJ31_RS07440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HKJ31_RS07455	COG0287	Prephenate dehydrogenase
HKJ31_RS07455	COG1605	Chorismate mutase
HKJ31_RS07480	COG0497	DNA recombination
HKJ31_RS07490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKJ31_RS07495	COG2914	Belongs to the UPF0125 (RnfH) family
HKJ31_RS07515	COG1278	Cold shock
HKJ31_RS07535	COG2954	triphosphatase activity
HKJ31_RS07545	COG0745	RESPONSE REGULATOR receiver
HKJ31_RS07550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HKJ31_RS07555	COG0438	transferase activity, transferring glycosyl groups
HKJ31_RS07565	COG0438	transferase activity, transferring glycosyl groups
HKJ31_RS07625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ31_RS07630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKJ31_RS07645	COG1064	alcohol dehydrogenase
HKJ31_RS07665	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HKJ31_RS07690	COG3609	addiction module antidote protein, CC2985 family
HKJ31_RS07700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKJ31_RS07705	COG0675	Transposase, IS605 OrfB family
HKJ31_RS07715	COG0436	Aminotransferase
HKJ31_RS07780	COG0196	riboflavin kinase activity
HKJ31_RS07785	COG0728	peptidoglycan biosynthetic process
HKJ31_RS07790	COG0268	Binds directly to 16S ribosomal RNA
HKJ31_RS07810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKJ31_RS07830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKJ31_RS07835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HKJ31_RS07850	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HKJ31_RS07860	COG0776	regulation of translation
HKJ31_RS07905	COG0395	ABC-type sugar transport system, permease component
HKJ31_RS07910	COG1175	transmembrane transport
HKJ31_RS07935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKJ31_RS07955	COG0436	Aminotransferase
HKJ31_RS07960	COG4133	protoheme IX ABC transporter activity
HKJ31_RS07980	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HKJ31_RS07990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKJ31_RS08020	COG5434	Belongs to the glycosyl hydrolase 28 family
HKJ31_RS08045	COG0402	S-adenosylhomocysteine deaminase activity
HKJ31_RS08055	COG1509	lysine 2,3-aminomutase activity
HKJ31_RS08090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKJ31_RS08095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKJ31_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ31_RS08140	COG0142	geranyltranstransferase activity
HKJ31_RS08150	COG0037	tRNA processing
HKJ31_RS08160	COG1785	Belongs to the alkaline phosphatase family
HKJ31_RS08165	COG1301	dicarboxylic acid transport
HKJ31_RS08175	COG0791	NLP P60 protein
HKJ31_RS08180	COG0791	NLP P60 protein
HKJ31_RS08190	COG2311	Membrane
HKJ31_RS08205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKJ31_RS08330	COG0351	phosphomethylpyrimidine kinase
HKJ31_RS08330	COG0352	thiamine-phosphate diphosphorylase activity
HKJ31_RS08340	COG1324	tolerance protein
HKJ31_RS08375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ31_RS08380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ31_RS08385	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKJ31_RS08400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HKJ31_RS08420	COG4774	siderophore transport
HKJ31_RS08445	COG1477	protein flavinylation
HKJ31_RS08450	COG1555	photosystem II stabilization
HKJ31_RS08455	COG3178	'Phosphotransferase
HKJ31_RS08460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HKJ31_RS08470	COG0628	permease
HKJ31_RS08480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HKJ31_RS08485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKJ31_RS08510	COG3590	peptidase
HKJ31_RS08570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HKJ31_RS08570	COG0519	Catalyzes the synthesis of GMP from XMP
HKJ31_RS08585	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HKJ31_RS08600	COG3107	peptidoglycan biosynthetic process
HKJ31_RS08620	COG2878	Part of a membrane complex involved in electron transport
HKJ31_RS08670	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HKJ31_RS08725	COG1611	Belongs to the LOG family
HKJ31_RS08730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HKJ31_RS08735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HKJ31_RS08745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKJ31_RS08775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HKJ31_RS08790	COG0330	HflC and HflK could
HKJ31_RS08795	COG0330	HflC and HflK could
HKJ31_RS08800	COG0604	alcohol dehydrogenase
HKJ31_RS08830	COG1183	phosphatidylcholine synthase activity
HKJ31_RS08850	COG0668	transmembrane transport
HKJ31_RS08855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKJ31_RS08870	COG1610	YqeY-like protein
HKJ31_RS08880	COG0358	DNA primase activity
HKJ31_RS08910	COG1074	ATP-dependent DNA helicase activity
HKJ31_RS08915	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HKJ31_RS08920	COG1127	ABC transporter
HKJ31_RS08925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HKJ31_RS08945	COG2853	Lipoprotein
HKJ31_RS08950	COG1322	Protein conserved in bacteria
HKJ31_RS08955	COG1116	anion transmembrane transporter activity
HKJ31_RS08965	COG0531	amino acid
HKJ31_RS08970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HKJ31_RS08975	COG0861	Integral membrane protein TerC family
HKJ31_RS09015	COG2193	ferroxidase activity
HKJ31_RS09045	COG2205	protein histidine kinase activity
HKJ31_RS09050	COG0745	RESPONSE REGULATOR receiver
HKJ31_RS09055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKJ31_RS09080	COG0542	response to heat
HKJ31_RS09095	COG2124	cytochrome p450
HKJ31_RS09100	COG2194	sulfuric ester hydrolase activity
HKJ31_RS09140	COG0667	Aldo Keto reductase
HKJ31_RS09145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKJ31_RS09155	COG0305	Participates in initiation and elongation during chromosome replication
HKJ31_RS09175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKJ31_RS09185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKJ31_RS09190	COG0277	FAD linked oxidase domain protein
HKJ31_RS09200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HKJ31_RS09205	COG4206	TonB-dependent receptor
HKJ31_RS09285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKJ31_RS09305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKJ31_RS09335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKJ31_RS09335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKJ31_RS09355	COG0488	(ABC) transporter
HKJ31_RS09365	COG3011	Protein conserved in bacteria
HKJ31_RS09380	COG0564	pseudouridine synthase activity
HKJ31_RS09405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKJ31_RS09430	COG0758	DNA mediated transformation
HKJ31_RS09475	COG2969	positive regulation of protein catabolic process
HKJ31_RS09480	COG0625	glutathione transferase activity
HKJ31_RS09485	COG2857	Cytochrome c1
HKJ31_RS09490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HKJ31_RS09495	COG0723	plastoquinol--plastocyanin reductase activity
HKJ31_RS09500	COG0741	lytic transglycosylase activity
HKJ31_RS09510	COG1702	phosphate starvation-inducible protein PhoH
HKJ31_RS09525	COG4535	Mg2 and Co2 transporter CorC
HKJ31_RS09535	COG0598	Magnesium transport protein CorA
HKJ31_RS09580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKJ31_RS09590	COG1199	ATP-dependent helicase activity
HKJ31_RS09600	COG0288	reversible hydration of carbon dioxide
HKJ31_RS09625	COG2011	ABC-type metal ion transport system permease component
HKJ31_RS09630	COG1464	Belongs to the NlpA lipoprotein family
HKJ31_RS09645	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKJ31_RS09650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKJ31_RS09665	COG0626	cystathionine gamma-synthase activity
HKJ31_RS09670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKJ31_RS09675	COG0739	heme binding
HKJ31_RS09700	COG1238	metal cluster binding
HKJ31_RS09715	COG5002	protein histidine kinase activity
HKJ31_RS09735	COG1388	LysM domain
HKJ31_RS09735	COG3858	chitin binding
HKJ31_RS09740	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HKJ31_RS09750	COG1472	Belongs to the glycosyl hydrolase 3 family
HKJ31_RS09765	COG3537	Alpha-1,2-mannosidase
HKJ31_RS09795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HKJ31_RS09800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HKJ31_RS09845	COG0469	pyruvate kinase activity
HKJ31_RS09865	COG0735	belongs to the Fur family
HKJ31_RS09875	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKJ31_RS09875	COG5297	Belongs to the glycosyl hydrolase family 6
HKJ31_RS09885	COG0612	Peptidase, M16
HKJ31_RS09905	COG4305	rare lipoprotein A
HKJ31_RS09915	COG0739	heme binding
HKJ31_RS09925	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HKJ31_RS09940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HKJ31_RS09970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKJ31_RS09985	COG3116	cell division
HKJ31_RS10000	COG3273	potassium ion transport
HKJ31_RS10000	COG0471	metal ion transport
HKJ31_RS10055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HKJ31_RS10100	COG0730	response to heat
HKJ31_RS10120	COG0860	N-Acetylmuramoyl-L-alanine amidase
HKJ31_RS10125	COG0802	atpase or kinase
HKJ31_RS10130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HKJ31_RS10130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKJ31_RS10135	COG1570	exodeoxyribonuclease VII activity
HKJ31_RS10200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKJ31_RS10220	COG0745	RESPONSE REGULATOR receiver
HKJ31_RS10225	COG0642	Histidine kinase
HKJ31_RS10235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HKJ31_RS10275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKJ31_RS10285	COG2831	hemolysin activation secretion protein
HKJ31_RS10310	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HKJ31_RS10350	COG0316	Belongs to the HesB IscA family
HKJ31_RS10385	COG0697	spore germination
HKJ31_RS10390	COG0671	phosphoesterase, PA-phosphatase related
HKJ31_RS10395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKJ31_RS10405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HKJ31_RS10410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKJ31_RS10425	COG1132	(ABC) transporter
HKJ31_RS10430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HKJ31_RS10435	COG1538	Outer membrane efflux protein
HKJ31_RS10465	COG0745	RESPONSE REGULATOR receiver
HKJ31_RS10470	COG4783	chaperone-mediated protein folding
HKJ31_RS10480	COG0473	3-isopropylmalate dehydrogenase activity
HKJ31_RS10490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKJ31_RS10495	COG3083	sulfuric ester hydrolase activity
HKJ31_RS10500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HKJ31_RS10525	COG0564	pseudouridine synthase activity
HKJ31_RS10530	COG1530	ribonuclease E activity
HKJ31_RS10535	COG2197	response regulator
HKJ31_RS10550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKJ31_RS10575	COG1278	Cold shock
HKJ31_RS10580	COG5001	Diguanylate cyclase
HKJ31_RS10580	COG4251	negative regulation of phosphorylation
HKJ31_RS10580	COG3706	GGDEF domain
HKJ31_RS10580	COG2203	Gaf domain
HKJ31_RS10590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKJ31_RS10635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKJ31_RS10640	COG0250	Participates in transcription elongation, termination and antitermination
HKJ31_RS10645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HKJ31_RS10655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKJ31_RS10675	COG0012	GTP binding
HKJ31_RS10690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKJ31_RS10755	COG2095	MarC family integral membrane protein
HKJ31_RS10760	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HKJ31_RS10785	COG2132	Multicopper oxidase
HKJ31_RS10795	COG0210	DNA helicase
HKJ31_RS10805	COG0616	signal peptide processing
HKJ31_RS10825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKJ31_RS10840	COG2201	protein-glutamate methylesterase activity
HKJ31_RS10845	COG2177	Part of the ABC transporter FtsEX involved in
HKJ31_RS10850	COG2884	Cell division ATP-binding protein ftsE
HKJ31_RS10855	COG0513	Belongs to the DEAD box helicase family
HKJ31_RS10860	COG3118	belongs to the thioredoxin family
HKJ31_RS10865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKJ31_RS10880	COG0793	Belongs to the peptidase S41A family
HKJ31_RS10885	COG4942	peptidase
HKJ31_RS10900	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKJ31_RS10905	COG0493	'glutamate synthase
HKJ31_RS10910	COG0067	glutamate synthase
HKJ31_RS10910	COG0069	glutamate synthase activity
HKJ31_RS10910	COG0070	glutamate synthase
HKJ31_RS10955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKJ31_RS10995	COG1280	lysine exporter protein (LysE YggA)
HKJ31_RS11010	COG4942	peptidase
HKJ31_RS11060	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HKJ31_RS11160	COG1487	ribonuclease activity
HKJ31_RS11165	COG4691	Plasmid stability protein
HKJ31_RS11250	COG0594	ribonuclease P activity