locus-tag	class	description
LZ759_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LZ759_RS00020	COG0187	DNA topoisomerase II activity
LZ759_RS00030	COG0501	Belongs to the peptidase M48B family
LZ759_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ759_RS00150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ759_RS00160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ759_RS00170	COG0511	ligase activity, forming carbon-carbon bonds
LZ759_RS00175	COG0439	Biotin carboxylase
LZ759_RS00180	COG0210	DNA helicase
LZ759_RS00205	COG1040	competence protein
LZ759_RS00215	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ759_RS00255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ759_RS00265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ759_RS00290	COG3121	Chaperone
LZ759_RS00295	COG3539	Fimbrial protein
LZ759_RS00300	COG1546	Belongs to the CinA family
LZ759_RS00305	COG0477	Major facilitator Superfamily
LZ759_RS00310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ759_RS00325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ759_RS00330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZ759_RS00340	COG1534	Rna-binding protein
LZ759_RS00370	COG1560	Kdo2-lipid A biosynthetic process
LZ759_RS00375	COG1519	Transferase
LZ759_RS00395	COG0336	Belongs to the RNA methyltransferase TrmD family
LZ759_RS00415	COG1393	Belongs to the ArsC family
LZ759_RS00425	COG0367	asparagine synthase
LZ759_RS00435	COG2070	2-Nitropropane dioxygenase
LZ759_RS00465	COG0339	signal peptide processing
LZ759_RS00550	COG4221	oxidoreductase activity
LZ759_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ759_RS00580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ759_RS00630	COG2223	nitrite transmembrane transporter activity
LZ759_RS00640	COG0739	heme binding
LZ759_RS00675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ759_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
LZ759_RS00700	COG1272	protein, Hemolysin III
LZ759_RS00705	COG0463	Glycosyl transferase, family 2
LZ759_RS00710	COG0084	hydrolase, TatD family'
LZ759_RS00740	COG0330	HflC and HflK could
LZ759_RS00745	COG3956	TIGRFAM MazG family protein
LZ759_RS00755	COG0494	nUDIX hydrolase
LZ759_RS00765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ759_RS00770	COG0513	Belongs to the DEAD box helicase family
LZ759_RS00775	COG0720	synthase
LZ759_RS00800	COG1981	membrane
LZ759_RS00835	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ759_RS00865	COG0006	proline dipeptidase activity
LZ759_RS00885	COG1862	Preprotein translocase
LZ759_RS00890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ759_RS00895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ759_RS00905	COG0617	tRNA 3'-terminal CCA addition
LZ759_RS00945	COG0195	Participates in both transcription termination and antitermination
LZ759_RS00975	COG1733	regulation of RNA biosynthetic process
LZ759_RS00980	COG0702	epimerase
LZ759_RS01030	COG2086	electron transfer activity
LZ759_RS01060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ759_RS01090	COG0477	Major facilitator Superfamily
LZ759_RS01110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ759_RS01115	COG0671	phosphoesterase, PA-phosphatase related
LZ759_RS01130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ759_RS01135	COG0628	permease
LZ759_RS01155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ759_RS01160	COG1090	epimerase
LZ759_RS01165	COG0318	PFAM AMP-dependent synthetase and ligase
LZ759_RS01185	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ759_RS01230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ759_RS01255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ759_RS01275	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ759_RS01280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ759_RS01285	COG1034	ATP synthesis coupled electron transport
LZ759_RS01320	COG1007	ATP synthesis coupled electron transport
LZ759_RS01325	COG1028	Short-chain dehydrogenase reductase Sdr
LZ759_RS01330	COG2851	Citrate transporter
LZ759_RS01345	COG0642	Histidine kinase
LZ759_RS01360	COG2205	protein histidine kinase activity
LZ759_RS01360	COG0784	Response regulator, receiver
LZ759_RS01380	COG0280	phosphate acetyltransferase
LZ759_RS01380	COG0281	malic enzyme
LZ759_RS01390	COG0742	ribosomal rna small subunit methyltransferase
LZ759_RS01405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ759_RS01425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ759_RS01450	COG2166	iron-sulfur cluster assembly
LZ759_RS01480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ759_RS01555	COG1321	iron dependent repressor
LZ759_RS01575	COG1946	Acyl-CoA thioesterase
LZ759_RS01650	COG0750	zinc metalloprotease
LZ759_RS01660	COG0575	Belongs to the CDS family
LZ759_RS01665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZ759_RS01695	COG0528	UMP kinase activity
LZ759_RS01740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZ759_RS01750	COG0354	folic acid binding
LZ759_RS01760	COG2009	succinate dehydrogenase
LZ759_RS01765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ759_RS01775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ759_RS01805	COG0811	peptide transport
LZ759_RS01960	COG3772	lysozyme
LZ759_RS02040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ759_RS02115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ759_RS02140	COG1024	Enoyl-CoA hydratase
LZ759_RS02145	COG0527	aspartate kinase activity
LZ759_RS02165	COG0494	nUDIX hydrolase
LZ759_RS02170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ759_RS02180	COG0424	maF-like protein
LZ759_RS02195	COG0312	modulator of DNA gyrase
LZ759_RS02205	COG0312	modulator of DNA gyrase
LZ759_RS02210	COG0583	DNA-binding transcription factor activity
LZ759_RS02225	COG1064	alcohol dehydrogenase
LZ759_RS02285	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ759_RS02340	COG0255	Belongs to the universal ribosomal protein uL29 family
LZ759_RS02400	COG0201	protein transport
LZ759_RS02430	COG2960	long-chain fatty acid transporting porin activity
LZ759_RS02435	COG0606	chelatase, subunit chli
LZ759_RS02455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ759_RS02515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ759_RS02520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ759_RS02535	COG1187	pseudouridine synthase activity
LZ759_RS02560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ759_RS02565	COG0625	glutathione transferase activity
LZ759_RS02575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ759_RS02580	COG1217	gtp-binding protein TYPA
LZ759_RS02620	COG0842	Transport permease protein
LZ759_RS02625	COG1131	(ABC) transporter
LZ759_RS02645	COG1643	Atp-dependent helicase
LZ759_RS02660	COG1956	GAF domain-containing protein
LZ759_RS02670	COG0729	surface antigen
LZ759_RS02675	COG2911	Protein conserved in bacteria
LZ759_RS02780	COG0668	transmembrane transport
LZ759_RS02810	COG5297	Belongs to the glycosyl hydrolase family 6
LZ759_RS02815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZ759_RS02850	COG2733	membrane
LZ759_RS02855	COG1253	flavin adenine dinucleotide binding
LZ759_RS02920	COG0644	oxidoreductase
LZ759_RS02920	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ759_RS02935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ759_RS02935	COG3218	ABC-type transport auxiliary lipoprotein component
LZ759_RS02940	COG1127	ABC transporter
LZ759_RS02945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ759_RS02980	COG0629	single-stranded DNA binding
LZ759_RS03000	COG4969	Belongs to the N-Me-Phe pilin family
LZ759_RS03145	COG1077	Cell shape determining protein MreB Mrl
LZ759_RS03155	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ759_RS03160	COG0768	penicillin binding
LZ759_RS03165	COG0772	Belongs to the SEDS family
LZ759_RS03175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ759_RS03195	COG2894	cell division
LZ759_RS03215	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ759_RS03230	COG2353	YceI-like domain
LZ759_RS03235	COG0784	Response regulator, receiver
LZ759_RS03235	COG2198	Histidine kinase
LZ759_RS03235	COG2205	protein histidine kinase activity
LZ759_RS03280	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ759_RS03285	COG4208	sulfate ABC transporter
LZ759_RS03310	COG1846	Transcriptional regulator
LZ759_RS03340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZ759_RS03350	COG0741	lytic transglycosylase activity
LZ759_RS03375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ759_RS03410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ759_RS03420	COG0514	ATP-dependent DNA helicase (RecQ)
LZ759_RS03425	COG0783	Belongs to the Dps family
LZ759_RS03430	COG1643	Atp-dependent helicase
LZ759_RS03445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ759_RS03450	COG1845	cytochrome c oxidase, subunit III
LZ759_RS03455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ759_RS03460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ759_RS03465	COG0142	geranyltranstransferase activity
LZ759_RS03470	COG0629	single-stranded DNA binding
LZ759_RS03495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ759_RS03530	COG1137	ATPase activity
LZ759_RS03545	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ759_RS03590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ759_RS03600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ759_RS03615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LZ759_RS03635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ759_RS03665	COG0542	response to heat
LZ759_RS03685	COG0492	ferredoxin-NADP+ reductase activity
LZ759_RS03705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ759_RS03715	COG4191	Histidine kinase
LZ759_RS03720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ759_RS03725	COG1028	Short-chain dehydrogenase reductase Sdr
LZ759_RS03755	COG1609	Transcriptional regulator
LZ759_RS03760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ759_RS03765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ759_RS03770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ759_RS03775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ759_RS03780	COG0726	polysaccharide deacetylase
LZ759_RS03785	COG0297	glycogen (starch) synthase activity
LZ759_RS03805	COG0719	Fe-S assembly protein
LZ759_RS03810	COG0396	ATPase activity
LZ759_RS03815	COG0719	Fe-S assembly protein
LZ759_RS03820	COG1959	2 iron, 2 sulfur cluster binding
LZ759_RS03875	COG0308	aminopeptidase N
LZ759_RS03920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ759_RS03945	COG1561	YicC-like family, N-terminal region
LZ759_RS03960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ759_RS04005	COG5295	Hep Hag repeat protein
LZ759_RS04010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ759_RS04015	COG1459	type II secretion system
LZ759_RS04020	COG2165	general secretion pathway protein
LZ759_RS04025	COG4970	Tfp pilus assembly protein FimT
LZ759_RS04030	COG2165	general secretion pathway protein
LZ759_RS04035	COG4795	General secretion pathway protein
LZ759_RS04040	COG3156	type II secretion system protein K
LZ759_RS04045	COG3166	PFAM Fimbrial assembly family protein
LZ759_RS04060	COG1450	Type ii and iii secretion system protein
LZ759_RS04075	COG3634	alkyl hydroperoxide reductase activity
LZ759_RS04080	COG0583	DNA-binding transcription factor activity
LZ759_RS04150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ759_RS04170	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ759_RS04175	COG0567	Dehydrogenase, E1 component
LZ759_RS04180	COG2850	peptidyl-arginine hydroxylation
LZ759_RS04230	COG0675	Transposase, IS605 OrfB family
LZ759_RS04245	COG3772	lysozyme
LZ759_RS04295	COG0675	Transposase, IS605 OrfB family
LZ759_RS04455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ759_RS04460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ759_RS04465	COG2902	Dehydrogenase
LZ759_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
LZ759_RS04515	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ759_RS04560	COG2925	Exonuclease
LZ759_RS04570	COG0025	NhaP-type Na H and K H
LZ759_RS04590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ759_RS04615	COG0006	proline dipeptidase activity
LZ759_RS04625	COG0778	Nitroreductase
LZ759_RS04660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ759_RS04700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ759_RS04710	COG0557	exoribonuclease II activity
LZ759_RS04720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ759_RS04735	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ759_RS04740	COG1289	transmembrane transporter activity
LZ759_RS04755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ759_RS04765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ759_RS04785	COG0596	Alpha beta hydrolase
LZ759_RS04790	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ759_RS04795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZ759_RS04795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZ759_RS04835	COG0840	transmembrane signaling receptor activity
LZ759_RS04840	COG0643	Histidine kinase
LZ759_RS04840	COG0784	Response regulator, receiver
LZ759_RS04840	COG2198	Histidine kinase
LZ759_RS04870	COG0285	dihydrofolate synthase activity
LZ759_RS04880	COG0339	signal peptide processing
LZ759_RS04900	COG1301	dicarboxylic acid transport
LZ759_RS04905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ759_RS04915	COG2091	lysine biosynthetic process via aminoadipic acid
LZ759_RS04950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ759_RS04975	COG0084	hydrolase, TatD family'
LZ759_RS04990	COG0552	protein localization to endoplasmic reticulum
LZ759_RS05035	COG0824	Thioesterase
LZ759_RS05060	COG2885	chlorophyll binding
LZ759_RS05070	COG0602	queuosine metabolic process
LZ759_RS05090	COG0386	Belongs to the glutathione peroxidase family
LZ759_RS05110	COG0406	alpha-ribazole phosphatase activity
LZ759_RS05240	COG3852	Histidine kinase
LZ759_RS05245	COG2204	response regulator
LZ759_RS05260	COG0004	ammonium transporteR
LZ759_RS05265	COG0347	Belongs to the P(II) protein family
LZ759_RS05270	COG0174	glutamine synthetase
LZ759_RS05275	COG1968	undecaprenyl-diphosphatase activity
LZ759_RS05280	COG2353	YceI-like domain
LZ759_RS05340	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ759_RS05345	COG1764	response to oxidative stress
LZ759_RS05350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ759_RS05395	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ759_RS05405	COG0714	Associated with various cellular activities
LZ759_RS05425	COG0537	adenosine 5'-monophosphoramidase activity
LZ759_RS05490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ759_RS05520	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LZ759_RS05545	COG4969	Belongs to the N-Me-Phe pilin family
LZ759_RS05560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ759_RS05565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LZ759_RS05575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ759_RS05590	COG0251	oxidation-reduction process
LZ759_RS05650	COG0675	Transposase, IS605 OrfB family
LZ759_RS05710	COG3772	lysozyme
LZ759_RS05810	COG3617	BRO family, N-terminal domain
LZ759_RS05845	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ759_RS05845	COG0392	lysyltransferase activity
LZ759_RS05855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ759_RS05865	COG0463	Glycosyl transferase, family 2
LZ759_RS05910	COG3275	phosphorelay sensor kinase activity
LZ759_RS05915	COG0400	carboxylic ester hydrolase activity
LZ759_RS05935	COG2226	methyltransferase
LZ759_RS05950	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ759_RS05955	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ759_RS05965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ759_RS05995	COG0386	Belongs to the glutathione peroxidase family
LZ759_RS06000	COG1131	(ABC) transporter
LZ759_RS06030	COG3657	addiction module killer protein
LZ759_RS06035	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ759_RS06105	COG2369	cell adhesion
LZ759_RS06120	COG3567	Phage-associated protein, HI1409 family
LZ759_RS06125	COG5410	chromosome segregation
LZ759_RS06150	COG3772	lysozyme
LZ759_RS06220	COG0489	protein tyrosine kinase activity
LZ759_RS06230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ759_RS06290	COG0488	(ABC) transporter
LZ759_RS06310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ759_RS06310	COG4651	solute:proton antiporter activity
LZ759_RS06370	COG0859	PFAM glycosyl transferase family 9
LZ759_RS06385	COG0631	protein serine/threonine phosphatase activity
LZ759_RS06390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ759_RS06395	COG0328	RNA-DNA hybrid ribonuclease activity
LZ759_RS06420	COG2183	response to ionizing radiation
LZ759_RS06435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ759_RS06440	COG3118	belongs to the thioredoxin family
LZ759_RS06490	COG2951	lytic endotransglycosylase activity
LZ759_RS06495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZ759_RS06630	COG3210	domain, Protein
LZ759_RS06630	COG3210	domain, Protein
LZ759_RS06665	COG0277	FAD linked oxidase domain protein
LZ759_RS06670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ759_RS06675	COG0531	amino acid
LZ759_RS06680	COG0531	amino acid
LZ759_RS06765	COG0527	aspartate kinase activity
LZ759_RS06765	COG0460	homoserine dehydrogenase
LZ759_RS06770	COG0540	Belongs to the ATCase OTCase family
LZ759_RS06785	COG1686	Belongs to the peptidase S11 family
LZ759_RS06815	COG4953	penicillin-binding protein 1C
LZ759_RS06845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ759_RS06910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ759_RS06915	COG0823	Involved in the tonB-independent uptake of proteins
LZ759_RS06915	COG1506	peptidase
LZ759_RS06920	COG1297	OPT oligopeptide transporter protein
LZ759_RS06950	COG0676	glucose-6-phosphate 1-epimerase activity
LZ759_RS06960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ759_RS06965	COG1335	isochorismatase
LZ759_RS06970	COG0318	PFAM AMP-dependent synthetase and ligase
LZ759_RS06980	COG0463	Glycosyl transferase, family 2
LZ759_RS06995	COG1192	Involved in chromosome partitioning
LZ759_RS07060	COG3772	lysozyme
LZ759_RS07105	COG0077	Prephenate dehydratase
LZ759_RS07105	COG1605	Chorismate mutase
LZ759_RS07120	COG1668	transmembrane transport
LZ759_RS07125	COG4555	ABC transporter
LZ759_RS07150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ759_RS07165	COG0287	Prephenate dehydrogenase
LZ759_RS07165	COG1605	Chorismate mutase
LZ759_RS07200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ759_RS07205	COG2914	Belongs to the UPF0125 (RnfH) family
LZ759_RS07225	COG1278	Cold shock
LZ759_RS07235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ759_RS07245	COG2954	triphosphatase activity
LZ759_RS07255	COG0745	RESPONSE REGULATOR receiver
LZ759_RS07260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ759_RS07265	COG0438	transferase activity, transferring glycosyl groups
LZ759_RS07275	COG0438	transferase activity, transferring glycosyl groups
LZ759_RS07335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ759_RS07340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ759_RS07365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ759_RS07400	COG3041	Addiction module toxin RelE StbE family
LZ759_RS07405	COG3609	addiction module antidote protein, CC2985 family
LZ759_RS07415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZ759_RS07420	COG0675	Transposase, IS605 OrfB family
LZ759_RS07430	COG0436	Aminotransferase
LZ759_RS07495	COG0196	riboflavin kinase activity
LZ759_RS07500	COG0728	peptidoglycan biosynthetic process
LZ759_RS07505	COG0268	Binds directly to 16S ribosomal RNA
LZ759_RS07525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZ759_RS07545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZ759_RS07550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ759_RS07565	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ759_RS07575	COG0776	regulation of translation
LZ759_RS07620	COG0395	ABC-type sugar transport system, permease component
LZ759_RS07625	COG1175	transmembrane transport
LZ759_RS07650	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LZ759_RS07670	COG0436	Aminotransferase
LZ759_RS07695	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZ759_RS07705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ759_RS07735	COG5434	Belongs to the glycosyl hydrolase 28 family
LZ759_RS07760	COG0402	S-adenosylhomocysteine deaminase activity
LZ759_RS07770	COG1509	lysine 2,3-aminomutase activity
LZ759_RS07805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ759_RS07810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ759_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
LZ759_RS07915	COG0142	geranyltranstransferase activity
LZ759_RS07925	COG0037	tRNA processing
LZ759_RS07940	COG1301	dicarboxylic acid transport
LZ759_RS07950	COG0791	NLP P60 protein
LZ759_RS07955	COG0791	NLP P60 protein
LZ759_RS07965	COG2311	Membrane
LZ759_RS07980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ759_RS08105	COG0352	thiamine-phosphate diphosphorylase activity
LZ759_RS08105	COG0351	phosphomethylpyrimidine kinase
LZ759_RS08115	COG1324	tolerance protein
LZ759_RS08150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ759_RS08155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ759_RS08160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ759_RS08175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ759_RS08195	COG4774	siderophore transport
LZ759_RS08220	COG1477	protein flavinylation
LZ759_RS08225	COG1555	photosystem II stabilization
LZ759_RS08230	COG3178	'Phosphotransferase
LZ759_RS08235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ759_RS08245	COG0628	permease
LZ759_RS08260	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ759_RS08285	COG3590	peptidase
LZ759_RS08345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ759_RS08345	COG0519	Catalyzes the synthesis of GMP from XMP
LZ759_RS08360	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ759_RS08375	COG3107	peptidoglycan biosynthetic process
LZ759_RS08395	COG2878	Part of a membrane complex involved in electron transport
LZ759_RS08445	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LZ759_RS08495	COG1611	Belongs to the LOG family
LZ759_RS08500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ759_RS08505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ759_RS08515	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ759_RS08545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ759_RS08560	COG0330	HflC and HflK could
LZ759_RS08565	COG0330	HflC and HflK could
LZ759_RS08570	COG0604	alcohol dehydrogenase
LZ759_RS08600	COG1183	phosphatidylcholine synthase activity
LZ759_RS08620	COG0668	transmembrane transport
LZ759_RS08625	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ759_RS08640	COG1610	YqeY-like protein
LZ759_RS08650	COG0358	DNA primase activity
LZ759_RS08685	COG1074	ATP-dependent DNA helicase activity
LZ759_RS08690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ759_RS08695	COG1127	ABC transporter
LZ759_RS08700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ759_RS08720	COG2853	Lipoprotein
LZ759_RS08725	COG1322	Protein conserved in bacteria
LZ759_RS08730	COG1116	anion transmembrane transporter activity
LZ759_RS08740	COG0531	amino acid
LZ759_RS08745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ759_RS08750	COG0861	Integral membrane protein TerC family
LZ759_RS08780	COG0784	Response regulator, receiver
LZ759_RS08780	COG5002	protein histidine kinase activity
LZ759_RS08790	COG2193	ferroxidase activity
LZ759_RS08875	COG2124	cytochrome p450
LZ759_RS08920	COG0667	Aldo Keto reductase
LZ759_RS08925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ759_RS08935	COG0305	Participates in initiation and elongation during chromosome replication
LZ759_RS08955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ759_RS08965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ759_RS08970	COG0277	FAD linked oxidase domain protein
LZ759_RS08980	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LZ759_RS08985	COG4206	TonB-dependent receptor
LZ759_RS09015	COG0675	Transposase, IS605 OrfB family
LZ759_RS09065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ759_RS09085	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ759_RS09115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ759_RS09115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ759_RS09135	COG0488	(ABC) transporter
LZ759_RS09145	COG3011	Protein conserved in bacteria
LZ759_RS09160	COG0564	pseudouridine synthase activity
LZ759_RS09185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ759_RS09210	COG0758	DNA mediated transformation
LZ759_RS09255	COG2969	positive regulation of protein catabolic process
LZ759_RS09260	COG0625	glutathione transferase activity
LZ759_RS09265	COG2857	Cytochrome c1
LZ759_RS09270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ759_RS09275	COG0723	plastoquinol--plastocyanin reductase activity
LZ759_RS09280	COG0741	lytic transglycosylase activity
LZ759_RS09290	COG1702	phosphate starvation-inducible protein PhoH
LZ759_RS09305	COG4535	Mg2 and Co2 transporter CorC
LZ759_RS09315	COG0598	Magnesium transport protein CorA
LZ759_RS09400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ759_RS09410	COG1199	ATP-dependent helicase activity
LZ759_RS09420	COG0288	reversible hydration of carbon dioxide
LZ759_RS09445	COG2011	ABC-type metal ion transport system permease component
LZ759_RS09450	COG1464	Belongs to the NlpA lipoprotein family
LZ759_RS09465	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ759_RS09470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZ759_RS09485	COG0626	cystathionine gamma-synthase activity
LZ759_RS09490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ759_RS09495	COG0739	heme binding
LZ759_RS09515	COG1238	metal cluster binding
LZ759_RS09535	COG5002	protein histidine kinase activity
LZ759_RS09555	COG1388	LysM domain
LZ759_RS09555	COG3858	chitin binding
LZ759_RS09560	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ759_RS09570	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ759_RS09585	COG3537	Alpha-1,2-mannosidase
LZ759_RS09610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ759_RS09615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ759_RS09655	COG0469	pyruvate kinase activity
LZ759_RS09675	COG0735	belongs to the Fur family
LZ759_RS09700	COG0612	Peptidase, M16
LZ759_RS09715	COG4305	rare lipoprotein A
LZ759_RS09725	COG0739	heme binding
LZ759_RS09735	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZ759_RS09750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ759_RS09780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ759_RS09795	COG3116	cell division
LZ759_RS09810	COG0471	metal ion transport
LZ759_RS09810	COG3273	potassium ion transport
LZ759_RS09860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ759_RS09925	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ759_RS09930	COG0802	atpase or kinase
LZ759_RS09935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ759_RS09935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ759_RS10005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZ759_RS10025	COG0745	RESPONSE REGULATOR receiver
LZ759_RS10030	COG0642	Histidine kinase
LZ759_RS10040	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ759_RS10085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ759_RS10095	COG2831	hemolysin activation secretion protein
LZ759_RS10120	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ759_RS10160	COG0316	Belongs to the HesB IscA family
LZ759_RS10200	COG0697	spore germination
LZ759_RS10205	COG0671	phosphoesterase, PA-phosphatase related
LZ759_RS10210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LZ759_RS10220	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ759_RS10225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZ759_RS10240	COG1132	(ABC) transporter
LZ759_RS10245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ759_RS10250	COG1538	Outer membrane efflux protein
LZ759_RS10280	COG0745	RESPONSE REGULATOR receiver
LZ759_RS10285	COG4783	chaperone-mediated protein folding
LZ759_RS10295	COG0473	3-isopropylmalate dehydrogenase activity
LZ759_RS10305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZ759_RS10310	COG3083	sulfuric ester hydrolase activity
LZ759_RS10315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ759_RS10340	COG0564	pseudouridine synthase activity
LZ759_RS10345	COG1530	ribonuclease E activity
LZ759_RS10350	COG2197	response regulator
LZ759_RS10365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ759_RS10380	COG0488	(ABC) transporter
LZ759_RS10395	COG1278	Cold shock
LZ759_RS10400	COG5001	Diguanylate cyclase
LZ759_RS10400	COG4251	negative regulation of phosphorylation
LZ759_RS10400	COG2203	Gaf domain
LZ759_RS10400	COG3706	GGDEF domain
LZ759_RS10410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZ759_RS10440	COG0222	ribosome binding
LZ759_RS10455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LZ759_RS10460	COG0250	Participates in transcription elongation, termination and antitermination
LZ759_RS10465	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZ759_RS10475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZ759_RS10495	COG0012	GTP binding
LZ759_RS10510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZ759_RS10585	COG2095	MarC family integral membrane protein
LZ759_RS10595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ759_RS10620	COG2132	Multicopper oxidase
LZ759_RS10630	COG0210	DNA helicase
LZ759_RS10640	COG0616	signal peptide processing
LZ759_RS10660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ759_RS10675	COG2201	protein-glutamate methylesterase activity
LZ759_RS10680	COG2177	Part of the ABC transporter FtsEX involved in
LZ759_RS10685	COG2884	Cell division ATP-binding protein ftsE
LZ759_RS10690	COG0513	Belongs to the DEAD box helicase family
LZ759_RS10695	COG3118	belongs to the thioredoxin family
LZ759_RS10700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ759_RS10715	COG0793	Belongs to the peptidase S41A family
LZ759_RS10720	COG4942	peptidase
LZ759_RS10735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ759_RS10740	COG0493	'glutamate synthase
LZ759_RS10745	COG0067	glutamate synthase
LZ759_RS10745	COG0069	glutamate synthase activity
LZ759_RS10745	COG0070	glutamate synthase
LZ759_RS10795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ759_RS10840	COG1280	lysine exporter protein (LysE YggA)
LZ759_RS10860	COG4942	peptidase
LZ759_RS10900	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ759_RS10915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LZ759_RS11050	COG1487	ribonuclease activity
LZ759_RS11055	COG4691	Plasmid stability protein
LZ759_RS11130	COG3210	domain, Protein
LZ759_RS11160	COG0594	ribonuclease P activity