locus-tag	class	description
HKJ32_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKJ32_RS00020	COG0187	DNA topoisomerase II activity
HKJ32_RS00030	COG0501	Belongs to the peptidase M48B family
HKJ32_RS00085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKJ32_RS00145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HKJ32_RS00155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKJ32_RS00165	COG0511	ligase activity, forming carbon-carbon bonds
HKJ32_RS00170	COG0439	Biotin carboxylase
HKJ32_RS00175	COG0210	DNA helicase
HKJ32_RS00205	COG1752	Esterase of the alpha-beta hydrolase superfamily
HKJ32_RS00245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HKJ32_RS00255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKJ32_RS00280	COG3121	Chaperone
HKJ32_RS00285	COG3539	Fimbrial protein
HKJ32_RS00290	COG1546	Belongs to the CinA family
HKJ32_RS00295	COG0477	Major facilitator Superfamily
HKJ32_RS00300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKJ32_RS00315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKJ32_RS00320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKJ32_RS00330	COG1534	Rna-binding protein
HKJ32_RS00360	COG1560	Kdo2-lipid A biosynthetic process
HKJ32_RS00365	COG1519	Transferase
HKJ32_RS00385	COG0336	Belongs to the RNA methyltransferase TrmD family
HKJ32_RS00405	COG1393	Belongs to the ArsC family
HKJ32_RS00415	COG0367	asparagine synthase
HKJ32_RS00425	COG2070	2-Nitropropane dioxygenase
HKJ32_RS00455	COG0339	signal peptide processing
HKJ32_RS00535	COG4221	oxidoreductase activity
HKJ32_RS00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKJ32_RS00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ32_RS00605	COG2223	nitrite transmembrane transporter activity
HKJ32_RS00615	COG0739	heme binding
HKJ32_RS00650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HKJ32_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ32_RS00675	COG1272	protein, Hemolysin III
HKJ32_RS00680	COG0463	Glycosyl transferase, family 2
HKJ32_RS00685	COG0084	hydrolase, TatD family'
HKJ32_RS00715	COG0330	HflC and HflK could
HKJ32_RS00720	COG3956	TIGRFAM MazG family protein
HKJ32_RS00730	COG0494	nUDIX hydrolase
HKJ32_RS00740	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HKJ32_RS00745	COG0513	Belongs to the DEAD box helicase family
HKJ32_RS00750	COG0720	synthase
HKJ32_RS00770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HKJ32_RS00805	COG3617	BRO family, N-terminal domain
HKJ32_RS00900	COG3772	lysozyme
HKJ32_RS00970	COG3093	addiction module antidote protein HigA
HKJ32_RS01085	COG0512	Glutamine amidotransferase of anthranilate synthase
HKJ32_RS01115	COG0006	proline dipeptidase activity
HKJ32_RS01135	COG1862	Preprotein translocase
HKJ32_RS01140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKJ32_RS01145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKJ32_RS01155	COG0617	tRNA 3'-terminal CCA addition
HKJ32_RS01195	COG0195	Participates in both transcription termination and antitermination
HKJ32_RS01225	COG1733	regulation of RNA biosynthetic process
HKJ32_RS01230	COG0702	epimerase
HKJ32_RS01280	COG2086	electron transfer activity
HKJ32_RS01310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ32_RS01335	COG0477	Major facilitator Superfamily
HKJ32_RS01355	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HKJ32_RS01360	COG0671	phosphoesterase, PA-phosphatase related
HKJ32_RS01375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKJ32_RS01380	COG0628	permease
HKJ32_RS01400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKJ32_RS01405	COG1090	epimerase
HKJ32_RS01410	COG0318	PFAM AMP-dependent synthetase and ligase
HKJ32_RS01430	COG1049	propionate catabolic process, 2-methylcitrate cycle
HKJ32_RS01480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ32_RS01505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKJ32_RS01525	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HKJ32_RS01530	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HKJ32_RS01535	COG1034	ATP synthesis coupled electron transport
HKJ32_RS01570	COG1007	ATP synthesis coupled electron transport
HKJ32_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ32_RS01580	COG2851	Citrate transporter
HKJ32_RS01595	COG0642	Histidine kinase
HKJ32_RS01610	COG0784	Response regulator, receiver
HKJ32_RS01610	COG2205	protein histidine kinase activity
HKJ32_RS01630	COG0280	phosphate acetyltransferase
HKJ32_RS01630	COG0281	malic enzyme
HKJ32_RS01640	COG0742	ribosomal rna small subunit methyltransferase
HKJ32_RS01655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HKJ32_RS01665	COG3706	GGDEF domain
HKJ32_RS01675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HKJ32_RS01700	COG2166	iron-sulfur cluster assembly
HKJ32_RS01730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKJ32_RS01800	COG1914	H( )-stimulated, divalent metal cation uptake system
HKJ32_RS01815	COG1946	Acyl-CoA thioesterase
HKJ32_RS01890	COG0750	zinc metalloprotease
HKJ32_RS01900	COG0575	Belongs to the CDS family
HKJ32_RS01905	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKJ32_RS01935	COG0528	UMP kinase activity
HKJ32_RS01980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKJ32_RS01990	COG0354	folic acid binding
HKJ32_RS02000	COG2009	succinate dehydrogenase
HKJ32_RS02005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HKJ32_RS02015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HKJ32_RS02045	COG0811	peptide transport
HKJ32_RS02200	COG3772	lysozyme
HKJ32_RS02285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKJ32_RS02325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKJ32_RS02325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKJ32_RS02355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HKJ32_RS02380	COG1024	Enoyl-CoA hydratase
HKJ32_RS02385	COG0527	aspartate kinase activity
HKJ32_RS02405	COG0494	nUDIX hydrolase
HKJ32_RS02410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HKJ32_RS02420	COG0424	maF-like protein
HKJ32_RS02425	COG1530	ribonuclease E activity
HKJ32_RS02435	COG0312	modulator of DNA gyrase
HKJ32_RS02445	COG0312	modulator of DNA gyrase
HKJ32_RS02450	COG0583	DNA-binding transcription factor activity
HKJ32_RS02465	COG1064	alcohol dehydrogenase
HKJ32_RS02520	COG0356	it plays a direct role in the translocation of protons across the membrane
HKJ32_RS02575	COG0255	Belongs to the universal ribosomal protein uL29 family
HKJ32_RS02635	COG0201	protein transport
HKJ32_RS02665	COG2960	long-chain fatty acid transporting porin activity
HKJ32_RS02670	COG0606	chelatase, subunit chli
HKJ32_RS02690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HKJ32_RS02750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKJ32_RS02755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKJ32_RS02770	COG1187	pseudouridine synthase activity
HKJ32_RS02775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HKJ32_RS02795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKJ32_RS02800	COG0625	glutathione transferase activity
HKJ32_RS02810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKJ32_RS02855	COG0842	Transport permease protein
HKJ32_RS02860	COG1131	(ABC) transporter
HKJ32_RS02880	COG1643	Atp-dependent helicase
HKJ32_RS02895	COG1956	GAF domain-containing protein
HKJ32_RS02905	COG0729	surface antigen
HKJ32_RS02910	COG2911	Protein conserved in bacteria
HKJ32_RS03005	COG0668	transmembrane transport
HKJ32_RS03035	COG5297	Belongs to the glycosyl hydrolase family 6
HKJ32_RS03070	COG2733	membrane
HKJ32_RS03075	COG1253	flavin adenine dinucleotide binding
HKJ32_RS03125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HKJ32_RS03140	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HKJ32_RS03140	COG0644	oxidoreductase
HKJ32_RS03155	COG3218	ABC-type transport auxiliary lipoprotein component
HKJ32_RS03155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HKJ32_RS03160	COG1127	ABC transporter
HKJ32_RS03165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HKJ32_RS03200	COG0629	single-stranded DNA binding
HKJ32_RS03225	COG4969	Belongs to the N-Me-Phe pilin family
HKJ32_RS03340	COG0675	Transposase, IS605 OrfB family
HKJ32_RS03375	COG1077	Cell shape determining protein MreB Mrl
HKJ32_RS03380	COG1792	Involved in formation and maintenance of cell shape
HKJ32_RS03385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HKJ32_RS03390	COG0768	penicillin binding
HKJ32_RS03395	COG0772	Belongs to the SEDS family
HKJ32_RS03405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKJ32_RS03425	COG2894	cell division
HKJ32_RS03445	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKJ32_RS03460	COG2353	YceI-like domain
HKJ32_RS03510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HKJ32_RS03515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HKJ32_RS03520	COG4208	sulfate ABC transporter
HKJ32_RS03545	COG1846	Transcriptional regulator
HKJ32_RS03575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HKJ32_RS03585	COG0741	lytic transglycosylase activity
HKJ32_RS03610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKJ32_RS03645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKJ32_RS03655	COG0514	ATP-dependent DNA helicase (RecQ)
HKJ32_RS03660	COG0783	Belongs to the Dps family
HKJ32_RS03665	COG1643	Atp-dependent helicase
HKJ32_RS03675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HKJ32_RS03680	COG1845	cytochrome c oxidase, subunit III
HKJ32_RS03685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKJ32_RS03690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HKJ32_RS03695	COG0142	geranyltranstransferase activity
HKJ32_RS03700	COG0629	single-stranded DNA binding
HKJ32_RS03740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKJ32_RS03775	COG1137	ATPase activity
HKJ32_RS03790	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HKJ32_RS03800	COG0271	Belongs to the BolA IbaG family
HKJ32_RS03835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKJ32_RS03845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKJ32_RS03860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HKJ32_RS03880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKJ32_RS03910	COG0542	response to heat
HKJ32_RS03930	COG0492	ferredoxin-NADP+ reductase activity
HKJ32_RS03950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HKJ32_RS03960	COG4191	Histidine kinase
HKJ32_RS03965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKJ32_RS03970	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ32_RS04000	COG1609	Transcriptional regulator
HKJ32_RS04005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HKJ32_RS04010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKJ32_RS04015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKJ32_RS04020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKJ32_RS04025	COG0726	polysaccharide deacetylase
HKJ32_RS04030	COG0297	glycogen (starch) synthase activity
HKJ32_RS04045	COG0719	Fe-S assembly protein
HKJ32_RS04050	COG0396	ATPase activity
HKJ32_RS04055	COG0719	Fe-S assembly protein
HKJ32_RS04060	COG1959	2 iron, 2 sulfur cluster binding
HKJ32_RS04170	COG3077	Addiction module antitoxin, RelB DinJ family
HKJ32_RS04245	COG3772	lysozyme
HKJ32_RS04350	COG3617	BRO family, N-terminal domain
HKJ32_RS04390	COG0308	aminopeptidase N
HKJ32_RS04435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKJ32_RS04460	COG1561	YicC-like family, N-terminal region
HKJ32_RS04475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HKJ32_RS04515	COG5295	Hep Hag repeat protein
HKJ32_RS04520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKJ32_RS04525	COG1459	type II secretion system
HKJ32_RS04530	COG2165	general secretion pathway protein
HKJ32_RS04535	COG4970	Tfp pilus assembly protein FimT
HKJ32_RS04540	COG2165	general secretion pathway protein
HKJ32_RS04545	COG4795	General secretion pathway protein
HKJ32_RS04550	COG3156	type II secretion system protein K
HKJ32_RS04555	COG3166	PFAM Fimbrial assembly family protein
HKJ32_RS04570	COG1450	Type ii and iii secretion system protein
HKJ32_RS04585	COG3634	alkyl hydroperoxide reductase activity
HKJ32_RS04590	COG0583	DNA-binding transcription factor activity
HKJ32_RS04655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HKJ32_RS04675	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKJ32_RS04680	COG0567	Dehydrogenase, E1 component
HKJ32_RS04685	COG2850	peptidyl-arginine hydroxylation
HKJ32_RS04795	COG3772	lysozyme
HKJ32_RS04875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKJ32_RS04880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ32_RS04885	COG2902	Dehydrogenase
HKJ32_RS04925	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ32_RS04955	COG1472	Belongs to the glycosyl hydrolase 3 family
HKJ32_RS04975	COG2925	Exonuclease
HKJ32_RS04985	COG0025	NhaP-type Na H and K H
HKJ32_RS05005	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKJ32_RS05030	COG0006	proline dipeptidase activity
HKJ32_RS05040	COG0778	Nitroreductase
HKJ32_RS05075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKJ32_RS05110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKJ32_RS05125	COG0557	exoribonuclease II activity
HKJ32_RS05135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKJ32_RS05150	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKJ32_RS05155	COG1289	transmembrane transporter activity
HKJ32_RS05180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HKJ32_RS05190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKJ32_RS05205	COG0596	Alpha beta hydrolase
HKJ32_RS05210	COG0727	PFAM Uncharacterised protein family (UPF0153)
HKJ32_RS05215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKJ32_RS05215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HKJ32_RS05255	COG0840	transmembrane signaling receptor activity
HKJ32_RS05260	COG2198	Histidine kinase
HKJ32_RS05260	COG0784	Response regulator, receiver
HKJ32_RS05260	COG0643	Histidine kinase
HKJ32_RS05290	COG0285	dihydrofolate synthase activity
HKJ32_RS05300	COG0339	signal peptide processing
HKJ32_RS05320	COG1301	dicarboxylic acid transport
HKJ32_RS05325	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKJ32_RS05335	COG2091	lysine biosynthetic process via aminoadipic acid
HKJ32_RS05370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKJ32_RS05400	COG0084	hydrolase, TatD family'
HKJ32_RS05415	COG0552	protein localization to endoplasmic reticulum
HKJ32_RS05460	COG0824	Thioesterase
HKJ32_RS05485	COG2885	chlorophyll binding
HKJ32_RS05495	COG0602	queuosine metabolic process
HKJ32_RS05510	COG3104	oligopeptide transport
HKJ32_RS05515	COG0386	Belongs to the glutathione peroxidase family
HKJ32_RS05535	COG0406	alpha-ribazole phosphatase activity
HKJ32_RS05595	COG0582	viral genome integration into host DNA
HKJ32_RS05610	COG0629	single-stranded DNA binding
HKJ32_RS05630	COG5532	Uncharacterized conserved protein (DUF2303)
HKJ32_RS05715	COG3617	BRO family, N-terminal domain
HKJ32_RS05745	COG3772	lysozyme
HKJ32_RS05770	COG5410	chromosome segregation
HKJ32_RS05780	COG2369	cell adhesion
HKJ32_RS05875	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ32_RS05880	COG3657	addiction module killer protein
HKJ32_RS05985	COG0582	viral genome integration into host DNA
HKJ32_RS06180	COG3852	Histidine kinase
HKJ32_RS06185	COG2204	response regulator
HKJ32_RS06200	COG0004	ammonium transporteR
HKJ32_RS06205	COG0347	Belongs to the P(II) protein family
HKJ32_RS06210	COG0174	glutamine synthetase
HKJ32_RS06215	COG1968	undecaprenyl-diphosphatase activity
HKJ32_RS06220	COG2353	YceI-like domain
HKJ32_RS06325	COG3772	lysozyme
HKJ32_RS06425	COG3617	BRO family, N-terminal domain
HKJ32_RS06455	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HKJ32_RS06505	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HKJ32_RS06510	COG1764	response to oxidative stress
HKJ32_RS06515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ32_RS06525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKJ32_RS06550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKJ32_RS06560	COG1399	metal-binding, possibly nucleic acid-binding protein
HKJ32_RS06570	COG0714	Associated with various cellular activities
HKJ32_RS06590	COG0537	adenosine 5'-monophosphoramidase activity
HKJ32_RS06645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKJ32_RS06675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKJ32_RS06695	COG4969	Belongs to the N-Me-Phe pilin family
HKJ32_RS06710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKJ32_RS06715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKJ32_RS06725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKJ32_RS06740	COG0251	oxidation-reduction process
HKJ32_RS06745	COG0392	lysyltransferase activity
HKJ32_RS06745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKJ32_RS06755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HKJ32_RS06765	COG0463	Glycosyl transferase, family 2
HKJ32_RS06810	COG3275	phosphorelay sensor kinase activity
HKJ32_RS06815	COG0400	carboxylic ester hydrolase activity
HKJ32_RS06835	COG2226	methyltransferase
HKJ32_RS06845	COG2027	D-alanyl-D-alanine carboxypeptidase
HKJ32_RS06860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKJ32_RS06900	COG1131	(ABC) transporter
HKJ32_RS06955	COG3657	addiction module killer protein
HKJ32_RS06960	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKJ32_RS07025	COG2369	cell adhesion
HKJ32_RS07030	COG3567	Phage-associated protein, HI1409 family
HKJ32_RS07060	COG3772	lysozyme
HKJ32_RS07125	COG0489	protein tyrosine kinase activity
HKJ32_RS07135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKJ32_RS07195	COG0488	(ABC) transporter
HKJ32_RS07215	COG4651	solute:proton antiporter activity
HKJ32_RS07215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HKJ32_RS07275	COG0859	PFAM glycosyl transferase family 9
HKJ32_RS07290	COG0631	protein serine/threonine phosphatase activity
HKJ32_RS07295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKJ32_RS07300	COG0328	RNA-DNA hybrid ribonuclease activity
HKJ32_RS07325	COG2183	response to ionizing radiation
HKJ32_RS07340	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HKJ32_RS07345	COG3118	belongs to the thioredoxin family
HKJ32_RS07395	COG2951	lytic endotransglycosylase activity
HKJ32_RS07400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKJ32_RS07510	COG0277	FAD linked oxidase domain protein
HKJ32_RS07515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HKJ32_RS07520	COG0531	amino acid
HKJ32_RS07525	COG0531	amino acid
HKJ32_RS07610	COG0527	aspartate kinase activity
HKJ32_RS07610	COG0460	homoserine dehydrogenase
HKJ32_RS07615	COG0540	Belongs to the ATCase OTCase family
HKJ32_RS07630	COG1686	Belongs to the peptidase S11 family
HKJ32_RS07655	COG4953	penicillin-binding protein 1C
HKJ32_RS07675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKJ32_RS07745	COG1506	peptidase
HKJ32_RS07745	COG0823	Involved in the tonB-independent uptake of proteins
HKJ32_RS07750	COG1297	OPT oligopeptide transporter protein
HKJ32_RS07780	COG0676	glucose-6-phosphate 1-epimerase activity
HKJ32_RS07790	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKJ32_RS07795	COG1335	isochorismatase
HKJ32_RS07800	COG0318	PFAM AMP-dependent synthetase and ligase
HKJ32_RS07810	COG0463	Glycosyl transferase, family 2
HKJ32_RS07825	COG1192	Involved in chromosome partitioning
HKJ32_RS07885	COG3772	lysozyme
HKJ32_RS07940	COG1605	Chorismate mutase
HKJ32_RS07940	COG0077	Prephenate dehydratase
HKJ32_RS07955	COG1668	transmembrane transport
HKJ32_RS07960	COG4555	ABC transporter
HKJ32_RS07985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HKJ32_RS08000	COG1605	Chorismate mutase
HKJ32_RS08000	COG0287	Prephenate dehydrogenase
HKJ32_RS08025	COG0497	DNA recombination
HKJ32_RS08035	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKJ32_RS08040	COG2914	Belongs to the UPF0125 (RnfH) family
HKJ32_RS08060	COG1278	Cold shock
HKJ32_RS08080	COG2954	triphosphatase activity
HKJ32_RS08090	COG0745	RESPONSE REGULATOR receiver
HKJ32_RS08095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HKJ32_RS08100	COG0438	transferase activity, transferring glycosyl groups
HKJ32_RS08110	COG0438	transferase activity, transferring glycosyl groups
HKJ32_RS08170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKJ32_RS08175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKJ32_RS08190	COG1064	alcohol dehydrogenase
HKJ32_RS08210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HKJ32_RS08235	COG3609	addiction module antidote protein, CC2985 family
HKJ32_RS08245	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKJ32_RS08250	COG0675	Transposase, IS605 OrfB family
HKJ32_RS08260	COG0436	Aminotransferase
HKJ32_RS08325	COG0196	riboflavin kinase activity
HKJ32_RS08330	COG0728	peptidoglycan biosynthetic process
HKJ32_RS08335	COG0268	Binds directly to 16S ribosomal RNA
HKJ32_RS08355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKJ32_RS08375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKJ32_RS08380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HKJ32_RS08395	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HKJ32_RS08405	COG0776	regulation of translation
HKJ32_RS08450	COG0395	ABC-type sugar transport system, permease component
HKJ32_RS08455	COG1175	transmembrane transport
HKJ32_RS08480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKJ32_RS08505	COG0436	Aminotransferase
HKJ32_RS08510	COG4133	protoheme IX ABC transporter activity
HKJ32_RS08530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
HKJ32_RS08540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKJ32_RS08570	COG5434	Belongs to the glycosyl hydrolase 28 family
HKJ32_RS08595	COG0402	S-adenosylhomocysteine deaminase activity
HKJ32_RS08605	COG1509	lysine 2,3-aminomutase activity
HKJ32_RS08640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKJ32_RS08645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKJ32_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
HKJ32_RS08705	COG0142	geranyltranstransferase activity
HKJ32_RS08715	COG0037	tRNA processing
HKJ32_RS08730	COG1301	dicarboxylic acid transport
HKJ32_RS08740	COG0791	NLP P60 protein
HKJ32_RS08745	COG0791	NLP P60 protein
HKJ32_RS08755	COG2311	Membrane
HKJ32_RS08770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKJ32_RS08895	COG0351	phosphomethylpyrimidine kinase
HKJ32_RS08895	COG0352	thiamine-phosphate diphosphorylase activity
HKJ32_RS08905	COG1324	tolerance protein
HKJ32_RS08940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ32_RS08945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HKJ32_RS08950	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKJ32_RS08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HKJ32_RS08985	COG4774	siderophore transport
HKJ32_RS09010	COG1477	protein flavinylation
HKJ32_RS09015	COG1555	photosystem II stabilization
HKJ32_RS09020	COG3178	'Phosphotransferase
HKJ32_RS09025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HKJ32_RS09035	COG0628	permease
HKJ32_RS09045	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HKJ32_RS09050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKJ32_RS09075	COG3590	peptidase
HKJ32_RS09130	COG0519	Catalyzes the synthesis of GMP from XMP
HKJ32_RS09130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HKJ32_RS09145	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
HKJ32_RS09160	COG3107	peptidoglycan biosynthetic process
HKJ32_RS09180	COG2878	Part of a membrane complex involved in electron transport
HKJ32_RS09230	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HKJ32_RS09285	COG1611	Belongs to the LOG family
HKJ32_RS09290	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HKJ32_RS09295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HKJ32_RS09305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKJ32_RS09335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HKJ32_RS09350	COG0330	HflC and HflK could
HKJ32_RS09355	COG0330	HflC and HflK could
HKJ32_RS09360	COG0604	alcohol dehydrogenase
HKJ32_RS09390	COG1183	phosphatidylcholine synthase activity
HKJ32_RS09410	COG0668	transmembrane transport
HKJ32_RS09415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKJ32_RS09430	COG1610	YqeY-like protein
HKJ32_RS09440	COG0358	DNA primase activity
HKJ32_RS09475	COG1074	ATP-dependent DNA helicase activity
HKJ32_RS09480	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HKJ32_RS09485	COG1127	ABC transporter
HKJ32_RS09490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HKJ32_RS09510	COG2853	Lipoprotein
HKJ32_RS09515	COG1322	Protein conserved in bacteria
HKJ32_RS09520	COG1116	anion transmembrane transporter activity
HKJ32_RS09530	COG0531	amino acid
HKJ32_RS09535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HKJ32_RS09540	COG0861	Integral membrane protein TerC family
HKJ32_RS09580	COG2193	ferroxidase activity
HKJ32_RS09610	COG2205	protein histidine kinase activity
HKJ32_RS09615	COG0745	RESPONSE REGULATOR receiver
HKJ32_RS09625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKJ32_RS09685	COG5449	Phage conserved hypothetical protein BR0599
HKJ32_RS09730	COG3772	lysozyme
HKJ32_RS09745	COG0740	serine-type endopeptidase activity
HKJ32_RS09795	COG4197	protein conserved in bacteria, prophage-related
HKJ32_RS09870	COG4969	Belongs to the N-Me-Phe pilin family
HKJ32_RS09915	COG0542	response to heat
HKJ32_RS09930	COG2124	cytochrome p450
HKJ32_RS09935	COG2194	sulfuric ester hydrolase activity
HKJ32_RS09975	COG0667	Aldo Keto reductase
HKJ32_RS09980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKJ32_RS09990	COG0305	Participates in initiation and elongation during chromosome replication
HKJ32_RS10010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKJ32_RS10020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKJ32_RS10025	COG0277	FAD linked oxidase domain protein
HKJ32_RS10035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HKJ32_RS10040	COG4206	TonB-dependent receptor
HKJ32_RS10120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKJ32_RS10140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKJ32_RS10170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKJ32_RS10170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKJ32_RS10190	COG0488	(ABC) transporter
HKJ32_RS10200	COG3011	Protein conserved in bacteria
HKJ32_RS10210	COG0564	pseudouridine synthase activity
HKJ32_RS10235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKJ32_RS10260	COG0758	DNA mediated transformation
HKJ32_RS10305	COG2969	positive regulation of protein catabolic process
HKJ32_RS10310	COG0625	glutathione transferase activity
HKJ32_RS10315	COG2857	Cytochrome c1
HKJ32_RS10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HKJ32_RS10325	COG0723	plastoquinol--plastocyanin reductase activity
HKJ32_RS10330	COG0741	lytic transglycosylase activity
HKJ32_RS10340	COG1702	phosphate starvation-inducible protein PhoH
HKJ32_RS10355	COG4535	Mg2 and Co2 transporter CorC
HKJ32_RS10365	COG0598	Magnesium transport protein CorA
HKJ32_RS10430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKJ32_RS10440	COG1199	ATP-dependent helicase activity
HKJ32_RS10450	COG0288	reversible hydration of carbon dioxide
HKJ32_RS10475	COG2011	ABC-type metal ion transport system permease component
HKJ32_RS10480	COG1464	Belongs to the NlpA lipoprotein family
HKJ32_RS10495	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKJ32_RS10500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKJ32_RS10515	COG0626	cystathionine gamma-synthase activity
HKJ32_RS10520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKJ32_RS10525	COG0739	heme binding
HKJ32_RS10550	COG1238	metal cluster binding
HKJ32_RS10565	COG5002	protein histidine kinase activity
HKJ32_RS10585	COG3858	chitin binding
HKJ32_RS10585	COG1388	LysM domain
HKJ32_RS10590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HKJ32_RS10600	COG1472	Belongs to the glycosyl hydrolase 3 family
HKJ32_RS10615	COG3537	Alpha-1,2-mannosidase
HKJ32_RS10645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HKJ32_RS10650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HKJ32_RS10695	COG0469	pyruvate kinase activity
HKJ32_RS10715	COG0735	belongs to the Fur family
HKJ32_RS10725	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKJ32_RS10725	COG5297	Belongs to the glycosyl hydrolase family 6
HKJ32_RS10735	COG0612	Peptidase, M16
HKJ32_RS10755	COG4305	rare lipoprotein A
HKJ32_RS10765	COG0739	heme binding
HKJ32_RS10775	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HKJ32_RS10790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HKJ32_RS10820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKJ32_RS10835	COG3116	cell division
HKJ32_RS10850	COG0471	metal ion transport
HKJ32_RS10850	COG3273	potassium ion transport
HKJ32_RS10905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HKJ32_RS10950	COG0730	response to heat
HKJ32_RS10970	COG0860	N-Acetylmuramoyl-L-alanine amidase
HKJ32_RS10975	COG0802	atpase or kinase
HKJ32_RS10980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKJ32_RS10980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HKJ32_RS10985	COG1570	exodeoxyribonuclease VII activity
HKJ32_RS11050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKJ32_RS11075	COG0745	RESPONSE REGULATOR receiver
HKJ32_RS11080	COG0642	Histidine kinase
HKJ32_RS11090	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HKJ32_RS11135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKJ32_RS11145	COG2831	hemolysin activation secretion protein
HKJ32_RS11170	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HKJ32_RS11210	COG0316	Belongs to the HesB IscA family
HKJ32_RS11245	COG0697	spore germination
HKJ32_RS11250	COG0671	phosphoesterase, PA-phosphatase related
HKJ32_RS11255	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKJ32_RS11265	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
HKJ32_RS11270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKJ32_RS11285	COG1132	(ABC) transporter
HKJ32_RS11290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HKJ32_RS11295	COG1538	Outer membrane efflux protein
HKJ32_RS11325	COG0745	RESPONSE REGULATOR receiver
HKJ32_RS11330	COG4783	chaperone-mediated protein folding
HKJ32_RS11340	COG0473	3-isopropylmalate dehydrogenase activity
HKJ32_RS11350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKJ32_RS11355	COG3083	sulfuric ester hydrolase activity
HKJ32_RS11360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HKJ32_RS11385	COG0564	pseudouridine synthase activity
HKJ32_RS11390	COG1530	ribonuclease E activity
HKJ32_RS11410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKJ32_RS11440	COG1278	Cold shock
HKJ32_RS11445	COG5001	Diguanylate cyclase
HKJ32_RS11445	COG4251	negative regulation of phosphorylation
HKJ32_RS11445	COG3706	GGDEF domain
HKJ32_RS11445	COG2203	Gaf domain
HKJ32_RS11455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKJ32_RS11500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKJ32_RS11505	COG0250	Participates in transcription elongation, termination and antitermination
HKJ32_RS11510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HKJ32_RS11520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKJ32_RS11540	COG0012	GTP binding
HKJ32_RS11555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKJ32_RS11630	COG2095	MarC family integral membrane protein
HKJ32_RS11635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HKJ32_RS11660	COG2132	Multicopper oxidase
HKJ32_RS11670	COG0210	DNA helicase
HKJ32_RS11680	COG0616	signal peptide processing
HKJ32_RS11700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKJ32_RS11715	COG2201	protein-glutamate methylesterase activity
HKJ32_RS11720	COG2177	Part of the ABC transporter FtsEX involved in
HKJ32_RS11725	COG2884	Cell division ATP-binding protein ftsE
HKJ32_RS11730	COG0513	Belongs to the DEAD box helicase family
HKJ32_RS11735	COG3118	belongs to the thioredoxin family
HKJ32_RS11740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKJ32_RS11755	COG0793	Belongs to the peptidase S41A family
HKJ32_RS11760	COG4942	peptidase
HKJ32_RS11775	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKJ32_RS11780	COG0493	'glutamate synthase
HKJ32_RS11785	COG0067	glutamate synthase
HKJ32_RS11785	COG0070	glutamate synthase
HKJ32_RS11785	COG0069	glutamate synthase activity
HKJ32_RS11830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKJ32_RS11875	COG1280	lysine exporter protein (LysE YggA)
HKJ32_RS11890	COG4942	peptidase
HKJ32_RS11925	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKJ32_RS11940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HKJ32_RS12040	COG1487	ribonuclease activity
HKJ32_RS12045	COG4691	Plasmid stability protein
HKJ32_RS12135	COG0594	ribonuclease P activity