locus-tag	class	description
LZ754_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LZ754_RS00020	COG0187	DNA topoisomerase II activity
LZ754_RS00030	COG0501	Belongs to the peptidase M48B family
LZ754_RS00090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZ754_RS00150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZ754_RS00160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZ754_RS00170	COG0511	ligase activity, forming carbon-carbon bonds
LZ754_RS00175	COG0439	Biotin carboxylase
LZ754_RS00180	COG0210	DNA helicase
LZ754_RS00205	COG1040	competence protein
LZ754_RS00215	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZ754_RS00255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ754_RS00265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZ754_RS00290	COG3121	Chaperone
LZ754_RS00295	COG3539	Fimbrial protein
LZ754_RS00300	COG1546	Belongs to the CinA family
LZ754_RS00305	COG0477	Major facilitator Superfamily
LZ754_RS00310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZ754_RS00325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZ754_RS00330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZ754_RS00340	COG1534	Rna-binding protein
LZ754_RS00370	COG1560	Kdo2-lipid A biosynthetic process
LZ754_RS00375	COG1519	Transferase
LZ754_RS00395	COG0336	Belongs to the RNA methyltransferase TrmD family
LZ754_RS00415	COG1393	Belongs to the ArsC family
LZ754_RS00425	COG0367	asparagine synthase
LZ754_RS00435	COG2070	2-Nitropropane dioxygenase
LZ754_RS00550	COG4221	oxidoreductase activity
LZ754_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZ754_RS00580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ754_RS00635	COG2223	nitrite transmembrane transporter activity
LZ754_RS00645	COG0739	heme binding
LZ754_RS00680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZ754_RS00695	COG1028	Short-chain dehydrogenase reductase Sdr
LZ754_RS00705	COG1272	protein, Hemolysin III
LZ754_RS00710	COG0463	Glycosyl transferase, family 2
LZ754_RS00715	COG0084	hydrolase, TatD family'
LZ754_RS00745	COG0330	HflC and HflK could
LZ754_RS00750	COG3956	TIGRFAM MazG family protein
LZ754_RS00760	COG0494	nUDIX hydrolase
LZ754_RS00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZ754_RS00775	COG0513	Belongs to the DEAD box helicase family
LZ754_RS00780	COG0720	synthase
LZ754_RS00805	COG1981	membrane
LZ754_RS00840	COG0512	Glutamine amidotransferase of anthranilate synthase
LZ754_RS00870	COG0006	proline dipeptidase activity
LZ754_RS00890	COG1862	Preprotein translocase
LZ754_RS00895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ754_RS00900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZ754_RS00910	COG0617	tRNA 3'-terminal CCA addition
LZ754_RS00950	COG0195	Participates in both transcription termination and antitermination
LZ754_RS00980	COG1733	regulation of RNA biosynthetic process
LZ754_RS00985	COG0702	epimerase
LZ754_RS01030	COG2086	electron transfer activity
LZ754_RS01060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ754_RS01095	COG0477	Major facilitator Superfamily
LZ754_RS01115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZ754_RS01120	COG0671	phosphoesterase, PA-phosphatase related
LZ754_RS01135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZ754_RS01140	COG0628	permease
LZ754_RS01160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ754_RS01165	COG1090	epimerase
LZ754_RS01170	COG0318	PFAM AMP-dependent synthetase and ligase
LZ754_RS01190	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZ754_RS01230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ754_RS01260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LZ754_RS01280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LZ754_RS01285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LZ754_RS01290	COG1034	ATP synthesis coupled electron transport
LZ754_RS01325	COG1007	ATP synthesis coupled electron transport
LZ754_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
LZ754_RS01335	COG2851	Citrate transporter
LZ754_RS01350	COG0642	Histidine kinase
LZ754_RS01365	COG0784	Response regulator, receiver
LZ754_RS01365	COG2205	protein histidine kinase activity
LZ754_RS01385	COG0280	phosphate acetyltransferase
LZ754_RS01385	COG0281	malic enzyme
LZ754_RS01395	COG0742	ribosomal rna small subunit methyltransferase
LZ754_RS01410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZ754_RS01430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZ754_RS01455	COG2166	iron-sulfur cluster assembly
LZ754_RS01485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZ754_RS01580	COG1321	iron dependent repressor
LZ754_RS01585	COG1914	H( )-stimulated, divalent metal cation uptake system
LZ754_RS01600	COG1946	Acyl-CoA thioesterase
LZ754_RS01680	COG0750	zinc metalloprotease
LZ754_RS01690	COG0575	Belongs to the CDS family
LZ754_RS01695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZ754_RS01730	COG0528	UMP kinase activity
LZ754_RS01775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZ754_RS01785	COG0354	folic acid binding
LZ754_RS01795	COG2009	succinate dehydrogenase
LZ754_RS01800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZ754_RS01810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZ754_RS01840	COG0811	peptide transport
LZ754_RS02000	COG3772	lysozyme
LZ754_RS02060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ754_RS02080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ754_RS02155	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZ754_RS02180	COG1024	Enoyl-CoA hydratase
LZ754_RS02185	COG0527	aspartate kinase activity
LZ754_RS02205	COG0494	nUDIX hydrolase
LZ754_RS02210	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZ754_RS02220	COG0424	maF-like protein
LZ754_RS02235	COG0312	modulator of DNA gyrase
LZ754_RS02245	COG0312	modulator of DNA gyrase
LZ754_RS02250	COG0583	DNA-binding transcription factor activity
LZ754_RS02265	COG1064	alcohol dehydrogenase
LZ754_RS02325	COG0356	it plays a direct role in the translocation of protons across the membrane
LZ754_RS02380	COG0255	Belongs to the universal ribosomal protein uL29 family
LZ754_RS02440	COG0201	protein transport
LZ754_RS02470	COG2960	long-chain fatty acid transporting porin activity
LZ754_RS02475	COG0606	chelatase, subunit chli
LZ754_RS02495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LZ754_RS02555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ754_RS02560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZ754_RS02575	COG1187	pseudouridine synthase activity
LZ754_RS02580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZ754_RS02605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZ754_RS02610	COG0625	glutathione transferase activity
LZ754_RS02620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZ754_RS02625	COG1217	gtp-binding protein TYPA
LZ754_RS02665	COG0842	Transport permease protein
LZ754_RS02670	COG1131	(ABC) transporter
LZ754_RS02690	COG1643	Atp-dependent helicase
LZ754_RS02705	COG1956	GAF domain-containing protein
LZ754_RS02710	COG0729	surface antigen
LZ754_RS02715	COG2911	Protein conserved in bacteria
LZ754_RS02725	COG0582	viral genome integration into host DNA
LZ754_RS02805	COG2337	Toxic component of a toxin-antitoxin (TA) module
LZ754_RS02810	COG0582	viral genome integration into host DNA
LZ754_RS02955	COG0668	transmembrane transport
LZ754_RS02990	COG5297	Belongs to the glycosyl hydrolase family 6
LZ754_RS02995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZ754_RS03030	COG2733	membrane
LZ754_RS03035	COG1253	flavin adenine dinucleotide binding
LZ754_RS03065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LZ754_RS03085	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LZ754_RS03100	COG0644	oxidoreductase
LZ754_RS03100	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LZ754_RS03115	COG3218	ABC-type transport auxiliary lipoprotein component
LZ754_RS03115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZ754_RS03120	COG1127	ABC transporter
LZ754_RS03125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ754_RS03160	COG0629	single-stranded DNA binding
LZ754_RS03180	COG4969	Belongs to the N-Me-Phe pilin family
LZ754_RS03220	COG0675	Transposase, IS605 OrfB family
LZ754_RS03335	COG1077	Cell shape determining protein MreB Mrl
LZ754_RS03345	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZ754_RS03350	COG0768	penicillin binding
LZ754_RS03355	COG0772	Belongs to the SEDS family
LZ754_RS03365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ754_RS03385	COG2894	cell division
LZ754_RS03405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZ754_RS03420	COG2353	YceI-like domain
LZ754_RS03425	COG2198	Histidine kinase
LZ754_RS03425	COG2205	protein histidine kinase activity
LZ754_RS03425	COG0784	Response regulator, receiver
LZ754_RS03465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LZ754_RS03470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LZ754_RS03475	COG4208	sulfate ABC transporter
LZ754_RS03500	COG1846	Transcriptional regulator
LZ754_RS03530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZ754_RS03540	COG0741	lytic transglycosylase activity
LZ754_RS03565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZ754_RS03600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LZ754_RS03610	COG0514	ATP-dependent DNA helicase (RecQ)
LZ754_RS03615	COG0783	Belongs to the Dps family
LZ754_RS03620	COG1643	Atp-dependent helicase
LZ754_RS03635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LZ754_RS03640	COG1845	cytochrome c oxidase, subunit III
LZ754_RS03645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LZ754_RS03650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZ754_RS03655	COG0142	geranyltranstransferase activity
LZ754_RS03660	COG0629	single-stranded DNA binding
LZ754_RS03685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZ754_RS03720	COG1137	ATPase activity
LZ754_RS03735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZ754_RS03780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ754_RS03790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZ754_RS03795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZ754_RS03805	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LZ754_RS03830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZ754_RS03860	COG0542	response to heat
LZ754_RS03880	COG0492	ferredoxin-NADP+ reductase activity
LZ754_RS03900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZ754_RS03910	COG4191	Histidine kinase
LZ754_RS03915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZ754_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
LZ754_RS03950	COG1609	Transcriptional regulator
LZ754_RS03955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZ754_RS03960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZ754_RS03965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZ754_RS03970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZ754_RS03975	COG0726	polysaccharide deacetylase
LZ754_RS03980	COG0297	glycogen (starch) synthase activity
LZ754_RS03995	COG0719	Fe-S assembly protein
LZ754_RS04000	COG0396	ATPase activity
LZ754_RS04005	COG0719	Fe-S assembly protein
LZ754_RS04010	COG1959	2 iron, 2 sulfur cluster binding
LZ754_RS04065	COG0308	aminopeptidase N
LZ754_RS04110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZ754_RS04135	COG1561	YicC-like family, N-terminal region
LZ754_RS04150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZ754_RS04195	COG5295	Hep Hag repeat protein
LZ754_RS04200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZ754_RS04205	COG1459	type II secretion system
LZ754_RS04210	COG2165	general secretion pathway protein
LZ754_RS04215	COG4970	Tfp pilus assembly protein FimT
LZ754_RS04220	COG2165	general secretion pathway protein
LZ754_RS04225	COG4795	General secretion pathway protein
LZ754_RS04230	COG3156	type II secretion system protein K
LZ754_RS04235	COG3166	PFAM Fimbrial assembly family protein
LZ754_RS04250	COG1450	Type ii and iii secretion system protein
LZ754_RS04255	COG5295	Hep Hag repeat protein
LZ754_RS04265	COG3634	alkyl hydroperoxide reductase activity
LZ754_RS04270	COG0583	DNA-binding transcription factor activity
LZ754_RS04335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZ754_RS04355	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ754_RS04360	COG0567	Dehydrogenase, E1 component
LZ754_RS04365	COG2850	peptidyl-arginine hydroxylation
LZ754_RS04380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ754_RS04475	COG3772	lysozyme
LZ754_RS04560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ754_RS04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ754_RS04570	COG2902	Dehydrogenase
LZ754_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
LZ754_RS04665	COG2925	Exonuclease
LZ754_RS04680	COG0025	NhaP-type Na H and K H
LZ754_RS04700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZ754_RS04725	COG0006	proline dipeptidase activity
LZ754_RS04735	COG0778	Nitroreductase
LZ754_RS04770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZ754_RS04825	COG0557	exoribonuclease II activity
LZ754_RS04835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZ754_RS04850	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LZ754_RS04855	COG1289	transmembrane transporter activity
LZ754_RS04875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZ754_RS04885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZ754_RS04905	COG0596	Alpha beta hydrolase
LZ754_RS04910	COG0727	PFAM Uncharacterised protein family (UPF0153)
LZ754_RS04915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZ754_RS04915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZ754_RS04955	COG0840	transmembrane signaling receptor activity
LZ754_RS04960	COG2198	Histidine kinase
LZ754_RS04960	COG0784	Response regulator, receiver
LZ754_RS04960	COG0643	Histidine kinase
LZ754_RS04990	COG0285	dihydrofolate synthase activity
LZ754_RS05000	COG0339	signal peptide processing
LZ754_RS05020	COG1301	dicarboxylic acid transport
LZ754_RS05025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZ754_RS05035	COG2091	lysine biosynthetic process via aminoadipic acid
LZ754_RS05070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ754_RS05095	COG0084	hydrolase, TatD family'
LZ754_RS05110	COG0552	protein localization to endoplasmic reticulum
LZ754_RS05155	COG0824	Thioesterase
LZ754_RS05180	COG2885	chlorophyll binding
LZ754_RS05190	COG0602	queuosine metabolic process
LZ754_RS05210	COG0386	Belongs to the glutathione peroxidase family
LZ754_RS05230	COG0406	alpha-ribazole phosphatase activity
LZ754_RS05380	COG0675	Transposase, IS605 OrfB family
LZ754_RS05395	COG3852	Histidine kinase
LZ754_RS05400	COG2204	response regulator
LZ754_RS05420	COG0004	ammonium transporteR
LZ754_RS05425	COG0347	Belongs to the P(II) protein family
LZ754_RS05430	COG0174	glutamine synthetase
LZ754_RS05435	COG1968	undecaprenyl-diphosphatase activity
LZ754_RS05440	COG2353	YceI-like domain
LZ754_RS05590	COG3772	lysozyme
LZ754_RS05735	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZ754_RS05790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZ754_RS05795	COG1764	response to oxidative stress
LZ754_RS05800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ754_RS05810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LZ754_RS05845	COG1399	metal-binding, possibly nucleic acid-binding protein
LZ754_RS05855	COG0714	Associated with various cellular activities
LZ754_RS05875	COG0537	adenosine 5'-monophosphoramidase activity
LZ754_RS05935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZ754_RS05965	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LZ754_RS05990	COG4969	Belongs to the N-Me-Phe pilin family
LZ754_RS06005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZ754_RS06010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LZ754_RS06020	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LZ754_RS06035	COG0251	oxidation-reduction process
LZ754_RS06040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LZ754_RS06040	COG0392	lysyltransferase activity
LZ754_RS06050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZ754_RS06060	COG0463	Glycosyl transferase, family 2
LZ754_RS06105	COG3275	phosphorelay sensor kinase activity
LZ754_RS06110	COG0400	carboxylic ester hydrolase activity
LZ754_RS06130	COG2226	methyltransferase
LZ754_RS06145	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ754_RS06150	COG2027	D-alanyl-D-alanine carboxypeptidase
LZ754_RS06160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ754_RS06215	COG3617	BRO family, N-terminal domain
LZ754_RS06345	COG3772	lysozyme
LZ754_RS06500	COG1131	(ABC) transporter
LZ754_RS06530	COG3657	addiction module killer protein
LZ754_RS06535	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ754_RS06605	COG2369	cell adhesion
LZ754_RS06610	COG3567	Phage-associated protein, HI1409 family
LZ754_RS06615	COG5410	chromosome segregation
LZ754_RS06640	COG3772	lysozyme
LZ754_RS06705	COG0489	protein tyrosine kinase activity
LZ754_RS06715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZ754_RS06785	COG0488	(ABC) transporter
LZ754_RS06810	COG4651	solute:proton antiporter activity
LZ754_RS06810	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZ754_RS06870	COG0859	PFAM glycosyl transferase family 9
LZ754_RS06885	COG0631	protein serine/threonine phosphatase activity
LZ754_RS06890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LZ754_RS06895	COG0328	RNA-DNA hybrid ribonuclease activity
LZ754_RS06920	COG2183	response to ionizing radiation
LZ754_RS06935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LZ754_RS06940	COG3118	belongs to the thioredoxin family
LZ754_RS06990	COG2951	lytic endotransglycosylase activity
LZ754_RS06995	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZ754_RS07085	COG0277	FAD linked oxidase domain protein
LZ754_RS07090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZ754_RS07095	COG0531	amino acid
LZ754_RS07100	COG0531	amino acid
LZ754_RS07190	COG0460	homoserine dehydrogenase
LZ754_RS07190	COG0527	aspartate kinase activity
LZ754_RS07195	COG0540	Belongs to the ATCase OTCase family
LZ754_RS07210	COG1686	Belongs to the peptidase S11 family
LZ754_RS07235	COG4953	penicillin-binding protein 1C
LZ754_RS07255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZ754_RS07325	COG0823	Involved in the tonB-independent uptake of proteins
LZ754_RS07325	COG1506	peptidase
LZ754_RS07330	COG1297	OPT oligopeptide transporter protein
LZ754_RS07360	COG0676	glucose-6-phosphate 1-epimerase activity
LZ754_RS07370	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZ754_RS07375	COG1335	isochorismatase
LZ754_RS07380	COG0318	PFAM AMP-dependent synthetase and ligase
LZ754_RS07390	COG0463	Glycosyl transferase, family 2
LZ754_RS07405	COG1192	Involved in chromosome partitioning
LZ754_RS07465	COG3772	lysozyme
LZ754_RS07515	COG1605	Chorismate mutase
LZ754_RS07515	COG0077	Prephenate dehydratase
LZ754_RS07530	COG1668	transmembrane transport
LZ754_RS07535	COG4555	ABC transporter
LZ754_RS07560	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZ754_RS07575	COG1605	Chorismate mutase
LZ754_RS07575	COG0287	Prephenate dehydrogenase
LZ754_RS07600	COG0497	DNA recombination
LZ754_RS07610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ754_RS07615	COG2914	Belongs to the UPF0125 (RnfH) family
LZ754_RS07635	COG1278	Cold shock
LZ754_RS07645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LZ754_RS07655	COG2954	triphosphatase activity
LZ754_RS07670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LZ754_RS07675	COG0438	transferase activity, transferring glycosyl groups
LZ754_RS07685	COG0438	transferase activity, transferring glycosyl groups
LZ754_RS07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZ754_RS07750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZ754_RS07765	COG1064	alcohol dehydrogenase
LZ754_RS07790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ754_RS07815	COG3609	addiction module antidote protein, CC2985 family
LZ754_RS07825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LZ754_RS07830	COG0675	Transposase, IS605 OrfB family
LZ754_RS07840	COG0436	Aminotransferase
LZ754_RS07910	COG0196	riboflavin kinase activity
LZ754_RS07915	COG0728	peptidoglycan biosynthetic process
LZ754_RS07920	COG0268	Binds directly to 16S ribosomal RNA
LZ754_RS07940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZ754_RS07960	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZ754_RS07965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LZ754_RS07980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZ754_RS07990	COG0776	regulation of translation
LZ754_RS08035	COG0395	ABC-type sugar transport system, permease component
LZ754_RS08040	COG1175	transmembrane transport
LZ754_RS08065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LZ754_RS08090	COG0436	Aminotransferase
LZ754_RS08115	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZ754_RS08125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZ754_RS08155	COG5434	Belongs to the glycosyl hydrolase 28 family
LZ754_RS08180	COG0402	S-adenosylhomocysteine deaminase activity
LZ754_RS08190	COG1509	lysine 2,3-aminomutase activity
LZ754_RS08230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZ754_RS08235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZ754_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
LZ754_RS08295	COG0142	geranyltranstransferase activity
LZ754_RS08305	COG0037	tRNA processing
LZ754_RS08320	COG1301	dicarboxylic acid transport
LZ754_RS08330	COG0791	NLP P60 protein
LZ754_RS08335	COG0791	NLP P60 protein
LZ754_RS08345	COG2311	Membrane
LZ754_RS08360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZ754_RS08485	COG0352	thiamine-phosphate diphosphorylase activity
LZ754_RS08485	COG0351	phosphomethylpyrimidine kinase
LZ754_RS08495	COG1324	tolerance protein
LZ754_RS08535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LZ754_RS08540	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LZ754_RS08555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZ754_RS08575	COG4774	siderophore transport
LZ754_RS08600	COG1477	protein flavinylation
LZ754_RS08605	COG1555	photosystem II stabilization
LZ754_RS08610	COG3178	'Phosphotransferase
LZ754_RS08615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZ754_RS08625	COG0628	permease
LZ754_RS08635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LZ754_RS08640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZ754_RS08660	COG3590	peptidase
LZ754_RS08720	COG0519	Catalyzes the synthesis of GMP from XMP
LZ754_RS08720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZ754_RS08735	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZ754_RS08750	COG3107	peptidoglycan biosynthetic process
LZ754_RS08770	COG2878	Part of a membrane complex involved in electron transport
LZ754_RS08880	COG3657	addiction module killer protein
LZ754_RS08885	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ754_RS08915	COG3657	addiction module killer protein
LZ754_RS08920	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LZ754_RS08990	COG2369	cell adhesion
LZ754_RS08995	COG3567	Phage-associated protein, HI1409 family
LZ754_RS09000	COG5410	chromosome segregation
LZ754_RS09025	COG3772	lysozyme
LZ754_RS09040	COG0305	Participates in initiation and elongation during chromosome replication
LZ754_RS09055	COG3617	BRO family, N-terminal domain
LZ754_RS09090	COG4197	protein conserved in bacteria, prophage-related
LZ754_RS09145	COG5532	Uncharacterized conserved protein (DUF2303)
LZ754_RS09165	COG3617	BRO family, N-terminal domain
LZ754_RS09220	COG1611	Belongs to the LOG family
LZ754_RS09225	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZ754_RS09230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZ754_RS09240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZ754_RS09270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZ754_RS09285	COG0330	HflC and HflK could
LZ754_RS09290	COG0330	HflC and HflK could
LZ754_RS09295	COG0604	alcohol dehydrogenase
LZ754_RS09325	COG1183	phosphatidylcholine synthase activity
LZ754_RS09345	COG0668	transmembrane transport
LZ754_RS09350	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZ754_RS09365	COG1610	YqeY-like protein
LZ754_RS09375	COG0358	DNA primase activity
LZ754_RS09415	COG1074	ATP-dependent DNA helicase activity
LZ754_RS09420	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZ754_RS09425	COG1127	ABC transporter
LZ754_RS09430	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZ754_RS09450	COG2853	Lipoprotein
LZ754_RS09455	COG1322	Protein conserved in bacteria
LZ754_RS09460	COG1116	anion transmembrane transporter activity
LZ754_RS09470	COG0531	amino acid
LZ754_RS09475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZ754_RS09480	COG0861	Integral membrane protein TerC family
LZ754_RS09515	COG2193	ferroxidase activity
LZ754_RS09605	COG2194	sulfuric ester hydrolase activity
LZ754_RS09645	COG0667	Aldo Keto reductase
LZ754_RS09650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZ754_RS09660	COG0305	Participates in initiation and elongation during chromosome replication
LZ754_RS09680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZ754_RS09690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZ754_RS09695	COG0277	FAD linked oxidase domain protein
LZ754_RS09705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LZ754_RS09710	COG4206	TonB-dependent receptor
LZ754_RS09740	COG0675	Transposase, IS605 OrfB family
LZ754_RS09790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZ754_RS09810	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZ754_RS09840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ754_RS09840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZ754_RS09860	COG0488	(ABC) transporter
LZ754_RS09870	COG3011	Protein conserved in bacteria
LZ754_RS09880	COG0564	pseudouridine synthase activity
LZ754_RS09905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LZ754_RS09930	COG0758	DNA mediated transformation
LZ754_RS09975	COG2969	positive regulation of protein catabolic process
LZ754_RS09980	COG0625	glutathione transferase activity
LZ754_RS09985	COG2857	Cytochrome c1
LZ754_RS09990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZ754_RS09995	COG0723	plastoquinol--plastocyanin reductase activity
LZ754_RS10000	COG0741	lytic transglycosylase activity
LZ754_RS10010	COG1702	phosphate starvation-inducible protein PhoH
LZ754_RS10025	COG4535	Mg2 and Co2 transporter CorC
LZ754_RS10065	COG3210	domain, Protein
LZ754_RS10085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZ754_RS10095	COG1199	ATP-dependent helicase activity
LZ754_RS10105	COG0288	reversible hydration of carbon dioxide
LZ754_RS10130	COG2011	ABC-type metal ion transport system permease component
LZ754_RS10135	COG1464	Belongs to the NlpA lipoprotein family
LZ754_RS10150	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZ754_RS10155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZ754_RS10170	COG0626	cystathionine gamma-synthase activity
LZ754_RS10175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LZ754_RS10180	COG0739	heme binding
LZ754_RS10200	COG1238	metal cluster binding
LZ754_RS10220	COG5002	protein histidine kinase activity
LZ754_RS10240	COG3858	chitin binding
LZ754_RS10240	COG1388	LysM domain
LZ754_RS10245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
LZ754_RS10255	COG1472	Belongs to the glycosyl hydrolase 3 family
LZ754_RS10270	COG3537	Alpha-1,2-mannosidase
LZ754_RS10300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ754_RS10305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZ754_RS10345	COG0469	pyruvate kinase activity
LZ754_RS10365	COG0735	belongs to the Fur family
LZ754_RS10375	COG5297	Belongs to the glycosyl hydrolase family 6
LZ754_RS10375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ754_RS10385	COG0612	Peptidase, M16
LZ754_RS10405	COG4305	rare lipoprotein A
LZ754_RS10415	COG0739	heme binding
LZ754_RS10425	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZ754_RS10440	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZ754_RS10470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZ754_RS10485	COG3116	cell division
LZ754_RS10500	COG0471	metal ion transport
LZ754_RS10500	COG3273	potassium ion transport
LZ754_RS10555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZ754_RS10615	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZ754_RS10620	COG0802	atpase or kinase
LZ754_RS10625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZ754_RS10625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZ754_RS10695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LZ754_RS10715	COG0745	RESPONSE REGULATOR receiver
LZ754_RS10720	COG0642	Histidine kinase
LZ754_RS10730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LZ754_RS10775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LZ754_RS10810	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZ754_RS10850	COG0316	Belongs to the HesB IscA family
LZ754_RS10885	COG0697	spore germination
LZ754_RS10890	COG0671	phosphoesterase, PA-phosphatase related
LZ754_RS10895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LZ754_RS10905	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
LZ754_RS10910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LZ754_RS10925	COG1132	(ABC) transporter
LZ754_RS10930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZ754_RS10935	COG1538	Outer membrane efflux protein
LZ754_RS10965	COG0745	RESPONSE REGULATOR receiver
LZ754_RS10970	COG4783	chaperone-mediated protein folding
LZ754_RS10980	COG0473	3-isopropylmalate dehydrogenase activity
LZ754_RS10990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LZ754_RS10995	COG3083	sulfuric ester hydrolase activity
LZ754_RS11000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZ754_RS11025	COG0564	pseudouridine synthase activity
LZ754_RS11030	COG1530	ribonuclease E activity
LZ754_RS11035	COG2197	response regulator
LZ754_RS11050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZ754_RS11065	COG0488	(ABC) transporter
LZ754_RS11080	COG1278	Cold shock
LZ754_RS11085	COG5001	Diguanylate cyclase
LZ754_RS11085	COG4251	negative regulation of phosphorylation
LZ754_RS11085	COG3706	GGDEF domain
LZ754_RS11085	COG2203	Gaf domain
LZ754_RS11100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZ754_RS11130	COG0222	ribosome binding
LZ754_RS11145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LZ754_RS11150	COG0250	Participates in transcription elongation, termination and antitermination
LZ754_RS11155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZ754_RS11165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZ754_RS11185	COG0012	GTP binding
LZ754_RS11200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZ754_RS11275	COG2095	MarC family integral membrane protein
LZ754_RS11280	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZ754_RS11320	COG0210	DNA helicase
LZ754_RS11470	COG3772	lysozyme
LZ754_RS11540	COG2944	sequence-specific DNA binding
LZ754_RS11615	COG0616	signal peptide processing
LZ754_RS11635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZ754_RS11650	COG2201	protein-glutamate methylesterase activity
LZ754_RS11655	COG2177	Part of the ABC transporter FtsEX involved in
LZ754_RS11660	COG2884	Cell division ATP-binding protein ftsE
LZ754_RS11665	COG0513	Belongs to the DEAD box helicase family
LZ754_RS11670	COG3118	belongs to the thioredoxin family
LZ754_RS11675	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LZ754_RS11690	COG0793	Belongs to the peptidase S41A family
LZ754_RS11695	COG4942	peptidase
LZ754_RS11710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LZ754_RS11715	COG0493	'glutamate synthase
LZ754_RS11720	COG0067	glutamate synthase
LZ754_RS11720	COG0069	glutamate synthase activity
LZ754_RS11720	COG0070	glutamate synthase
LZ754_RS11770	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ754_RS11815	COG1280	lysine exporter protein (LysE YggA)
LZ754_RS11825	COG4942	peptidase
LZ754_RS11860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LZ754_RS11875	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LZ754_RS11980	COG1487	ribonuclease activity
LZ754_RS11985	COG4691	Plasmid stability protein
LZ754_RS12045	COG3210	domain, Protein
LZ754_RS12080	COG0594	ribonuclease P activity
LZ754_RS12145	COG3736	Type IV secretory pathway, component VirB8
LZ754_RS12300	COG1472	Belongs to the glycosyl hydrolase 3 family