locus-tag	class	description
IUD19_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IUD19_RS00020	COG0187	DNA topoisomerase II activity
IUD19_RS00030	COG0501	Belongs to the peptidase M48B family
IUD19_RS00095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUD19_RS00155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUD19_RS00165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUD19_RS00175	COG0511	ligase activity, forming carbon-carbon bonds
IUD19_RS00180	COG0439	Biotin carboxylase
IUD19_RS00185	COG0210	DNA helicase
IUD19_RS00210	COG1040	competence protein
IUD19_RS00220	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUD19_RS00260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUD19_RS00270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUD19_RS00295	COG3121	Chaperone
IUD19_RS00300	COG3539	Fimbrial protein
IUD19_RS00305	COG1546	Belongs to the CinA family
IUD19_RS00310	COG0477	Major facilitator Superfamily
IUD19_RS00315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUD19_RS00330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IUD19_RS00335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUD19_RS00345	COG1534	Rna-binding protein
IUD19_RS00375	COG1560	Kdo2-lipid A biosynthetic process
IUD19_RS00380	COG1519	Transferase
IUD19_RS00400	COG0336	Belongs to the RNA methyltransferase TrmD family
IUD19_RS00420	COG1393	Belongs to the ArsC family
IUD19_RS00430	COG0367	asparagine synthase
IUD19_RS00440	COG2070	2-Nitropropane dioxygenase
IUD19_RS00470	COG0339	signal peptide processing
IUD19_RS00550	COG4221	oxidoreductase activity
IUD19_RS00570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUD19_RS00580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD19_RS00625	COG2223	nitrite transmembrane transporter activity
IUD19_RS00635	COG0739	heme binding
IUD19_RS00670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUD19_RS00685	COG1028	Short-chain dehydrogenase reductase Sdr
IUD19_RS00695	COG1272	protein, Hemolysin III
IUD19_RS00700	COG0463	Glycosyl transferase, family 2
IUD19_RS00705	COG0084	hydrolase, TatD family'
IUD19_RS00735	COG0330	HflC and HflK could
IUD19_RS00740	COG3956	TIGRFAM MazG family protein
IUD19_RS00750	COG0494	nUDIX hydrolase
IUD19_RS00760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUD19_RS00765	COG0513	Belongs to the DEAD box helicase family
IUD19_RS00770	COG0720	synthase
IUD19_RS00795	COG1981	membrane
IUD19_RS00830	COG0512	Glutamine amidotransferase of anthranilate synthase
IUD19_RS00860	COG0006	proline dipeptidase activity
IUD19_RS00880	COG1862	Preprotein translocase
IUD19_RS00885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUD19_RS00890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUD19_RS00900	COG0617	tRNA 3'-terminal CCA addition
IUD19_RS00940	COG0195	Participates in both transcription termination and antitermination
IUD19_RS00970	COG1733	regulation of RNA biosynthetic process
IUD19_RS00975	COG0702	epimerase
IUD19_RS01025	COG2086	electron transfer activity
IUD19_RS01055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD19_RS01090	COG0477	Major facilitator Superfamily
IUD19_RS01110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUD19_RS01115	COG0671	phosphoesterase, PA-phosphatase related
IUD19_RS01130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUD19_RS01135	COG0628	permease
IUD19_RS01155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUD19_RS01160	COG1090	epimerase
IUD19_RS01165	COG0318	PFAM AMP-dependent synthetase and ligase
IUD19_RS01185	COG1049	propionate catabolic process, 2-methylcitrate cycle
IUD19_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD19_RS01260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUD19_RS01280	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IUD19_RS01285	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IUD19_RS01290	COG1034	ATP synthesis coupled electron transport
IUD19_RS01325	COG1007	ATP synthesis coupled electron transport
IUD19_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
IUD19_RS01335	COG2851	Citrate transporter
IUD19_RS01350	COG0642	Histidine kinase
IUD19_RS01365	COG0784	Response regulator, receiver
IUD19_RS01365	COG2205	protein histidine kinase activity
IUD19_RS01385	COG0281	malic enzyme
IUD19_RS01385	COG0280	phosphate acetyltransferase
IUD19_RS01395	COG0742	ribosomal rna small subunit methyltransferase
IUD19_RS01410	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUD19_RS01430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IUD19_RS01455	COG2166	iron-sulfur cluster assembly
IUD19_RS01485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUD19_RS01565	COG1914	H( )-stimulated, divalent metal cation uptake system
IUD19_RS01580	COG1946	Acyl-CoA thioesterase
IUD19_RS01660	COG0750	zinc metalloprotease
IUD19_RS01670	COG0575	Belongs to the CDS family
IUD19_RS01675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IUD19_RS01705	COG0528	UMP kinase activity
IUD19_RS01750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IUD19_RS01760	COG0354	folic acid binding
IUD19_RS01770	COG2009	succinate dehydrogenase
IUD19_RS01775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUD19_RS01785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUD19_RS01815	COG0811	peptide transport
IUD19_RS01890	COG3077	Addiction module antitoxin, RelB DinJ family
IUD19_RS01965	COG3772	lysozyme
IUD19_RS02040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD19_RS02085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUD19_RS02085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUD19_RS02115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IUD19_RS02140	COG1024	Enoyl-CoA hydratase
IUD19_RS02145	COG0527	aspartate kinase activity
IUD19_RS02165	COG0494	nUDIX hydrolase
IUD19_RS02170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUD19_RS02180	COG0424	maF-like protein
IUD19_RS02195	COG0312	modulator of DNA gyrase
IUD19_RS02205	COG0312	modulator of DNA gyrase
IUD19_RS02210	COG0583	DNA-binding transcription factor activity
IUD19_RS02225	COG1064	alcohol dehydrogenase
IUD19_RS02280	COG0356	it plays a direct role in the translocation of protons across the membrane
IUD19_RS02335	COG0255	Belongs to the universal ribosomal protein uL29 family
IUD19_RS02395	COG0201	protein transport
IUD19_RS02425	COG2960	long-chain fatty acid transporting porin activity
IUD19_RS02430	COG0606	chelatase, subunit chli
IUD19_RS02450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IUD19_RS02510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUD19_RS02515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUD19_RS02530	COG1187	pseudouridine synthase activity
IUD19_RS02535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUD19_RS02555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUD19_RS02560	COG0625	glutathione transferase activity
IUD19_RS02570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUD19_RS02575	COG1217	gtp-binding protein TYPA
IUD19_RS02615	COG0842	Transport permease protein
IUD19_RS02620	COG1131	(ABC) transporter
IUD19_RS02640	COG1643	Atp-dependent helicase
IUD19_RS02655	COG1956	GAF domain-containing protein
IUD19_RS02665	COG0729	surface antigen
IUD19_RS02670	COG2911	Protein conserved in bacteria
IUD19_RS02680	COG0582	viral genome integration into host DNA
IUD19_RS02840	COG0668	transmembrane transport
IUD19_RS02870	COG5297	Belongs to the glycosyl hydrolase family 6
IUD19_RS02910	COG2733	membrane
IUD19_RS02915	COG1253	flavin adenine dinucleotide binding
IUD19_RS02965	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IUD19_RS02980	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IUD19_RS02980	COG0644	oxidoreductase
IUD19_RS02995	COG3218	ABC-type transport auxiliary lipoprotein component
IUD19_RS02995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUD19_RS03000	COG1127	ABC transporter
IUD19_RS03005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUD19_RS03040	COG0629	single-stranded DNA binding
IUD19_RS03065	COG4969	Belongs to the N-Me-Phe pilin family
IUD19_RS03180	COG0675	Transposase, IS605 OrfB family
IUD19_RS03225	COG1077	Cell shape determining protein MreB Mrl
IUD19_RS03230	COG1792	Involved in formation and maintenance of cell shape
IUD19_RS03235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IUD19_RS03240	COG0768	penicillin binding
IUD19_RS03245	COG0772	Belongs to the SEDS family
IUD19_RS03255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUD19_RS03275	COG2894	cell division
IUD19_RS03295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IUD19_RS03310	COG2353	YceI-like domain
IUD19_RS03355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IUD19_RS03360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUD19_RS03365	COG4208	sulfate ABC transporter
IUD19_RS03390	COG1846	Transcriptional regulator
IUD19_RS03420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUD19_RS03430	COG0741	lytic transglycosylase activity
IUD19_RS03460	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUD19_RS03495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUD19_RS03505	COG0514	ATP-dependent DNA helicase (RecQ)
IUD19_RS03510	COG0783	Belongs to the Dps family
IUD19_RS03515	COG1643	Atp-dependent helicase
IUD19_RS03525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUD19_RS03530	COG1845	cytochrome c oxidase, subunit III
IUD19_RS03535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUD19_RS03540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUD19_RS03545	COG0142	geranyltranstransferase activity
IUD19_RS03590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUD19_RS03625	COG1137	ATPase activity
IUD19_RS03640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUD19_RS03650	COG0271	Belongs to the BolA IbaG family
IUD19_RS03685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUD19_RS03695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUD19_RS03710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IUD19_RS03730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUD19_RS03760	COG0542	response to heat
IUD19_RS03780	COG0492	ferredoxin-NADP+ reductase activity
IUD19_RS03800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUD19_RS03810	COG4191	Histidine kinase
IUD19_RS03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IUD19_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
IUD19_RS03850	COG1609	Transcriptional regulator
IUD19_RS03855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUD19_RS03860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUD19_RS03865	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUD19_RS03870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUD19_RS03875	COG0726	polysaccharide deacetylase
IUD19_RS03880	COG0297	glycogen (starch) synthase activity
IUD19_RS03895	COG0719	Fe-S assembly protein
IUD19_RS03900	COG0396	ATPase activity
IUD19_RS03905	COG0719	Fe-S assembly protein
IUD19_RS03910	COG1959	2 iron, 2 sulfur cluster binding
IUD19_RS03965	COG0308	aminopeptidase N
IUD19_RS04010	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUD19_RS04035	COG1561	YicC-like family, N-terminal region
IUD19_RS04050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUD19_RS04090	COG5295	Hep Hag repeat protein
IUD19_RS04095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUD19_RS04100	COG1459	type II secretion system
IUD19_RS04105	COG2165	general secretion pathway protein
IUD19_RS04110	COG4970	Tfp pilus assembly protein FimT
IUD19_RS04115	COG2165	general secretion pathway protein
IUD19_RS04120	COG4795	General secretion pathway protein
IUD19_RS04125	COG3156	type II secretion system protein K
IUD19_RS04130	COG3166	PFAM Fimbrial assembly family protein
IUD19_RS04145	COG1450	Type ii and iii secretion system protein
IUD19_RS04165	COG3634	alkyl hydroperoxide reductase activity
IUD19_RS04170	COG0583	DNA-binding transcription factor activity
IUD19_RS04240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUD19_RS04260	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUD19_RS04265	COG0567	Dehydrogenase, E1 component
IUD19_RS04270	COG2850	peptidyl-arginine hydroxylation
IUD19_RS04380	COG3772	lysozyme
IUD19_RS04460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUD19_RS04465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD19_RS04470	COG2902	Dehydrogenase
IUD19_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
IUD19_RS04540	COG1472	Belongs to the glycosyl hydrolase 3 family
IUD19_RS04560	COG2925	Exonuclease
IUD19_RS04570	COG0025	NhaP-type Na H and K H
IUD19_RS04590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUD19_RS04615	COG0006	proline dipeptidase activity
IUD19_RS04625	COG0778	Nitroreductase
IUD19_RS04660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUD19_RS04695	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IUD19_RS04710	COG0557	exoribonuclease II activity
IUD19_RS04720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IUD19_RS04735	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IUD19_RS04740	COG1289	transmembrane transporter activity
IUD19_RS04760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IUD19_RS04775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUD19_RS04790	COG0596	Alpha beta hydrolase
IUD19_RS04795	COG0727	PFAM Uncharacterised protein family (UPF0153)
IUD19_RS04800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IUD19_RS04800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUD19_RS04840	COG0840	transmembrane signaling receptor activity
IUD19_RS04845	COG0784	Response regulator, receiver
IUD19_RS04845	COG0643	Histidine kinase
IUD19_RS04845	COG2198	Histidine kinase
IUD19_RS04875	COG0285	dihydrofolate synthase activity
IUD19_RS04885	COG0339	signal peptide processing
IUD19_RS04905	COG1301	dicarboxylic acid transport
IUD19_RS04910	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUD19_RS04920	COG2091	lysine biosynthetic process via aminoadipic acid
IUD19_RS04955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUD19_RS04980	COG0084	hydrolase, TatD family'
IUD19_RS04995	COG0552	protein localization to endoplasmic reticulum
IUD19_RS05040	COG0824	Thioesterase
IUD19_RS05065	COG2885	chlorophyll binding
IUD19_RS05075	COG0602	queuosine metabolic process
IUD19_RS05095	COG0386	Belongs to the glutathione peroxidase family
IUD19_RS05115	COG0406	alpha-ribazole phosphatase activity
IUD19_RS05275	COG3852	Histidine kinase
IUD19_RS05280	COG2204	response regulator
IUD19_RS05295	COG0004	ammonium transporteR
IUD19_RS05300	COG0347	Belongs to the P(II) protein family
IUD19_RS05310	COG1968	undecaprenyl-diphosphatase activity
IUD19_RS05315	COG2353	YceI-like domain
IUD19_RS05425	COG3772	lysozyme
IUD19_RS05550	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUD19_RS05600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUD19_RS05605	COG1764	response to oxidative stress
IUD19_RS05610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD19_RS05620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IUD19_RS05645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUD19_RS05655	COG1399	metal-binding, possibly nucleic acid-binding protein
IUD19_RS05665	COG0714	Associated with various cellular activities
IUD19_RS05685	COG0537	adenosine 5'-monophosphoramidase activity
IUD19_RS05740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUD19_RS05770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IUD19_RS05790	COG4969	Belongs to the N-Me-Phe pilin family
IUD19_RS05805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUD19_RS05810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IUD19_RS05820	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IUD19_RS05835	COG0251	oxidation-reduction process
IUD19_RS05840	COG0392	lysyltransferase activity
IUD19_RS05840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IUD19_RS05850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUD19_RS05860	COG0463	Glycosyl transferase, family 2
IUD19_RS05905	COG3275	phosphorelay sensor kinase activity
IUD19_RS05910	COG0400	carboxylic ester hydrolase activity
IUD19_RS05930	COG2226	methyltransferase
IUD19_RS05945	COG2027	D-alanyl-D-alanine carboxypeptidase
IUD19_RS05960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUD19_RS05995	COG1131	(ABC) transporter
IUD19_RS06025	COG3657	addiction module killer protein
IUD19_RS06030	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUD19_RS06130	COG2369	cell adhesion
IUD19_RS06155	COG0582	viral genome integration into host DNA
IUD19_RS06160	COG3567	Phage-associated protein, HI1409 family
IUD19_RS06165	COG5410	chromosome segregation
IUD19_RS06190	COG3772	lysozyme
IUD19_RS06255	COG0489	protein tyrosine kinase activity
IUD19_RS06265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUD19_RS06325	COG0488	(ABC) transporter
IUD19_RS06345	COG4651	solute:proton antiporter activity
IUD19_RS06345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUD19_RS06405	COG0859	PFAM glycosyl transferase family 9
IUD19_RS06420	COG0631	protein serine/threonine phosphatase activity
IUD19_RS06425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUD19_RS06430	COG0328	RNA-DNA hybrid ribonuclease activity
IUD19_RS06455	COG2183	response to ionizing radiation
IUD19_RS06470	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUD19_RS06475	COG3118	belongs to the thioredoxin family
IUD19_RS06525	COG2951	lytic endotransglycosylase activity
IUD19_RS06530	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IUD19_RS06600	COG0277	FAD linked oxidase domain protein
IUD19_RS06605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUD19_RS06610	COG0531	amino acid
IUD19_RS06615	COG0531	amino acid
IUD19_RS06700	COG0460	homoserine dehydrogenase
IUD19_RS06700	COG0527	aspartate kinase activity
IUD19_RS06705	COG0540	Belongs to the ATCase OTCase family
IUD19_RS06720	COG1686	Belongs to the peptidase S11 family
IUD19_RS06745	COG4953	penicillin-binding protein 1C
IUD19_RS06765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUD19_RS06835	COG1506	peptidase
IUD19_RS06835	COG0823	Involved in the tonB-independent uptake of proteins
IUD19_RS06840	COG1297	OPT oligopeptide transporter protein
IUD19_RS06870	COG0676	glucose-6-phosphate 1-epimerase activity
IUD19_RS06880	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUD19_RS06885	COG1335	isochorismatase
IUD19_RS06890	COG0318	PFAM AMP-dependent synthetase and ligase
IUD19_RS06900	COG0463	Glycosyl transferase, family 2
IUD19_RS06915	COG1192	Involved in chromosome partitioning
IUD19_RS06975	COG3772	lysozyme
IUD19_RS07025	COG1605	Chorismate mutase
IUD19_RS07025	COG0077	Prephenate dehydratase
IUD19_RS07040	COG1668	transmembrane transport
IUD19_RS07045	COG4555	ABC transporter
IUD19_RS07070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUD19_RS07085	COG1605	Chorismate mutase
IUD19_RS07085	COG0287	Prephenate dehydrogenase
IUD19_RS07110	COG0497	DNA recombination
IUD19_RS07120	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD19_RS07125	COG2914	Belongs to the UPF0125 (RnfH) family
IUD19_RS07145	COG1278	Cold shock
IUD19_RS07155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IUD19_RS07165	COG2954	triphosphatase activity
IUD19_RS07175	COG0745	RESPONSE REGULATOR receiver
IUD19_RS07180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IUD19_RS07185	COG0438	transferase activity, transferring glycosyl groups
IUD19_RS07195	COG0438	transferase activity, transferring glycosyl groups
IUD19_RS07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUD19_RS07260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUD19_RS07275	COG1064	alcohol dehydrogenase
IUD19_RS07295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUD19_RS07320	COG3609	addiction module antidote protein, CC2985 family
IUD19_RS07330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IUD19_RS07335	COG0675	Transposase, IS605 OrfB family
IUD19_RS07345	COG0436	Aminotransferase
IUD19_RS07410	COG0196	riboflavin kinase activity
IUD19_RS07415	COG0728	peptidoglycan biosynthetic process
IUD19_RS07420	COG0268	Binds directly to 16S ribosomal RNA
IUD19_RS07440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IUD19_RS07460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IUD19_RS07465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUD19_RS07480	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUD19_RS07490	COG0776	regulation of translation
IUD19_RS07535	COG0395	ABC-type sugar transport system, permease component
IUD19_RS07540	COG1175	transmembrane transport
IUD19_RS07565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUD19_RS07590	COG0436	Aminotransferase
IUD19_RS07595	COG4133	protoheme IX ABC transporter activity
IUD19_RS07615	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUD19_RS07625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUD19_RS07655	COG5434	Belongs to the glycosyl hydrolase 28 family
IUD19_RS07680	COG0402	S-adenosylhomocysteine deaminase activity
IUD19_RS07690	COG1509	lysine 2,3-aminomutase activity
IUD19_RS07725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUD19_RS07730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUD19_RS07745	COG1028	Short-chain dehydrogenase reductase Sdr
IUD19_RS07790	COG0142	geranyltranstransferase activity
IUD19_RS07800	COG0037	tRNA processing
IUD19_RS07810	COG1301	dicarboxylic acid transport
IUD19_RS07815	COG0791	NLP P60 protein
IUD19_RS07820	COG0791	NLP P60 protein
IUD19_RS07830	COG2311	Membrane
IUD19_RS07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUD19_RS07970	COG0352	thiamine-phosphate diphosphorylase activity
IUD19_RS07970	COG0351	phosphomethylpyrimidine kinase
IUD19_RS07980	COG1324	tolerance protein
IUD19_RS08020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUD19_RS08025	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IUD19_RS08040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUD19_RS08060	COG4774	siderophore transport
IUD19_RS08085	COG1477	protein flavinylation
IUD19_RS08090	COG1555	photosystem II stabilization
IUD19_RS08095	COG3178	'Phosphotransferase
IUD19_RS08100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IUD19_RS08110	COG0628	permease
IUD19_RS08120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IUD19_RS08125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUD19_RS08145	COG3590	peptidase
IUD19_RS08200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUD19_RS08200	COG0519	Catalyzes the synthesis of GMP from XMP
IUD19_RS08215	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IUD19_RS08230	COG3107	peptidoglycan biosynthetic process
IUD19_RS08250	COG2878	Part of a membrane complex involved in electron transport
IUD19_RS08295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IUD19_RS08350	COG1611	Belongs to the LOG family
IUD19_RS08355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUD19_RS08360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUD19_RS08370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUD19_RS08400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUD19_RS08415	COG0330	HflC and HflK could
IUD19_RS08420	COG0330	HflC and HflK could
IUD19_RS08425	COG0604	alcohol dehydrogenase
IUD19_RS08455	COG1183	phosphatidylcholine synthase activity
IUD19_RS08475	COG0668	transmembrane transport
IUD19_RS08480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IUD19_RS08495	COG1610	YqeY-like protein
IUD19_RS08505	COG0358	DNA primase activity
IUD19_RS08540	COG1074	ATP-dependent DNA helicase activity
IUD19_RS08545	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IUD19_RS08550	COG1127	ABC transporter
IUD19_RS08555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUD19_RS08575	COG2853	Lipoprotein
IUD19_RS08580	COG1322	Protein conserved in bacteria
IUD19_RS08585	COG1116	anion transmembrane transporter activity
IUD19_RS08595	COG0531	amino acid
IUD19_RS08600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUD19_RS08605	COG0861	Integral membrane protein TerC family
IUD19_RS08645	COG2193	ferroxidase activity
IUD19_RS08690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUD19_RS08715	COG0542	response to heat
IUD19_RS08730	COG2124	cytochrome p450
IUD19_RS08735	COG2194	sulfuric ester hydrolase activity
IUD19_RS08775	COG0667	Aldo Keto reductase
IUD19_RS08780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUD19_RS08790	COG0305	Participates in initiation and elongation during chromosome replication
IUD19_RS08810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUD19_RS08820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUD19_RS08825	COG0277	FAD linked oxidase domain protein
IUD19_RS08835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUD19_RS08840	COG4206	TonB-dependent receptor
IUD19_RS08925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUD19_RS08945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IUD19_RS08975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUD19_RS08975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUD19_RS08995	COG0488	(ABC) transporter
IUD19_RS09005	COG3011	Protein conserved in bacteria
IUD19_RS09015	COG0564	pseudouridine synthase activity
IUD19_RS09040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUD19_RS09065	COG0758	DNA mediated transformation
IUD19_RS09110	COG2969	positive regulation of protein catabolic process
IUD19_RS09115	COG0625	glutathione transferase activity
IUD19_RS09120	COG2857	Cytochrome c1
IUD19_RS09125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUD19_RS09130	COG0723	plastoquinol--plastocyanin reductase activity
IUD19_RS09135	COG0741	lytic transglycosylase activity
IUD19_RS09145	COG1702	phosphate starvation-inducible protein PhoH
IUD19_RS09160	COG4535	Mg2 and Co2 transporter CorC
IUD19_RS09170	COG0598	Magnesium transport protein CorA
IUD19_RS09245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUD19_RS09255	COG1199	ATP-dependent helicase activity
IUD19_RS09270	COG0288	reversible hydration of carbon dioxide
IUD19_RS09295	COG2011	ABC-type metal ion transport system permease component
IUD19_RS09300	COG1464	Belongs to the NlpA lipoprotein family
IUD19_RS09315	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUD19_RS09320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUD19_RS09335	COG0626	cystathionine gamma-synthase activity
IUD19_RS09340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUD19_RS09345	COG0739	heme binding
IUD19_RS09365	COG1238	metal cluster binding
IUD19_RS09385	COG5002	protein histidine kinase activity
IUD19_RS09405	COG1388	LysM domain
IUD19_RS09405	COG3858	chitin binding
IUD19_RS09410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
IUD19_RS09420	COG1472	Belongs to the glycosyl hydrolase 3 family
IUD19_RS09435	COG3537	Alpha-1,2-mannosidase
IUD19_RS09465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUD19_RS09470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUD19_RS09515	COG0469	pyruvate kinase activity
IUD19_RS09535	COG0735	belongs to the Fur family
IUD19_RS09545	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUD19_RS09545	COG5297	Belongs to the glycosyl hydrolase family 6
IUD19_RS09555	COG0612	Peptidase, M16
IUD19_RS09575	COG4305	rare lipoprotein A
IUD19_RS09585	COG0739	heme binding
IUD19_RS09595	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IUD19_RS09610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUD19_RS09640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IUD19_RS09655	COG3116	cell division
IUD19_RS09670	COG3273	potassium ion transport
IUD19_RS09670	COG0471	metal ion transport
IUD19_RS09725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUD19_RS09775	COG0730	response to heat
IUD19_RS09795	COG0860	N-Acetylmuramoyl-L-alanine amidase
IUD19_RS09800	COG0802	atpase or kinase
IUD19_RS09805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUD19_RS09805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUD19_RS09810	COG1570	exodeoxyribonuclease VII activity
IUD19_RS09875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IUD19_RS09895	COG0745	RESPONSE REGULATOR receiver
IUD19_RS09900	COG0642	Histidine kinase
IUD19_RS09910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IUD19_RS09955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IUD19_RS09970	COG2831	hemolysin activation secretion protein
IUD19_RS09995	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IUD19_RS10035	COG0316	Belongs to the HesB IscA family
IUD19_RS10070	COG0697	spore germination
IUD19_RS10075	COG0671	phosphoesterase, PA-phosphatase related
IUD19_RS10080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IUD19_RS10090	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IUD19_RS10095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IUD19_RS10110	COG1132	(ABC) transporter
IUD19_RS10120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUD19_RS10125	COG1538	Outer membrane efflux protein
IUD19_RS10155	COG0745	RESPONSE REGULATOR receiver
IUD19_RS10160	COG4783	chaperone-mediated protein folding
IUD19_RS10170	COG0473	3-isopropylmalate dehydrogenase activity
IUD19_RS10180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUD19_RS10185	COG3083	sulfuric ester hydrolase activity
IUD19_RS10190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUD19_RS10215	COG0564	pseudouridine synthase activity
IUD19_RS10220	COG1530	ribonuclease E activity
IUD19_RS10225	COG2197	response regulator
IUD19_RS10240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUD19_RS10255	COG0488	(ABC) transporter
IUD19_RS10270	COG1278	Cold shock
IUD19_RS10275	COG3706	GGDEF domain
IUD19_RS10275	COG4251	negative regulation of phosphorylation
IUD19_RS10275	COG2203	Gaf domain
IUD19_RS10275	COG5001	Diguanylate cyclase
IUD19_RS10285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUD19_RS10330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IUD19_RS10335	COG0250	Participates in transcription elongation, termination and antitermination
IUD19_RS10340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUD19_RS10350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUD19_RS10370	COG0012	GTP binding
IUD19_RS10385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUD19_RS10455	COG2095	MarC family integral membrane protein
IUD19_RS10460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUD19_RS10485	COG2132	Multicopper oxidase
IUD19_RS10495	COG0210	DNA helicase
IUD19_RS10505	COG0616	signal peptide processing
IUD19_RS10525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUD19_RS10540	COG2201	protein-glutamate methylesterase activity
IUD19_RS10545	COG2177	Part of the ABC transporter FtsEX involved in
IUD19_RS10550	COG2884	Cell division ATP-binding protein ftsE
IUD19_RS10555	COG0513	Belongs to the DEAD box helicase family
IUD19_RS10560	COG3118	belongs to the thioredoxin family
IUD19_RS10565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IUD19_RS10580	COG0793	Belongs to the peptidase S41A family
IUD19_RS10585	COG4942	peptidase
IUD19_RS10600	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUD19_RS10605	COG0493	'glutamate synthase
IUD19_RS10610	COG0067	glutamate synthase
IUD19_RS10610	COG0069	glutamate synthase activity
IUD19_RS10610	COG0070	glutamate synthase
IUD19_RS10655	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IUD19_RS10695	COG1280	lysine exporter protein (LysE YggA)
IUD19_RS10710	COG4942	peptidase
IUD19_RS10745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IUD19_RS10760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IUD19_RS10870	COG1487	ribonuclease activity
IUD19_RS10875	COG4691	Plasmid stability protein
IUD19_RS10960	COG0594	ribonuclease P activity
IUD19_RS10975	COG3451	type IV secretory pathway VirB4
IUD19_RS11030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IUD19_RS11135	COG0675	Transposase, IS605 OrfB family
IUD19_RS11155	COG0629	single-stranded DNA binding
IUD19_RS11165	COG4962	Type ii secretion system protein e