locus-tag	class	description
D934_RS00040	COG0745	RESPONSE REGULATOR receiver
D934_RS00045	COG4783	chaperone-mediated protein folding
D934_RS00055	COG0473	3-isopropylmalate dehydrogenase activity
D934_RS00070	COG3083	sulfuric ester hydrolase activity
D934_RS00075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D934_RS00100	COG0564	pseudouridine synthase activity
D934_RS00105	COG1530	ribonuclease E activity
D934_RS00110	COG2197	response regulator
D934_RS00125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D934_RS00140	COG0488	(ABC) transporter
D934_RS00155	COG1278	Cold shock
D934_RS00255	COG0012	GTP binding
D934_RS00270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D934_RS00355	COG2095	MarC family integral membrane protein
D934_RS00360	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D934_RS00385	COG2132	Multicopper oxidase
D934_RS00395	COG0210	DNA helicase
D934_RS00405	COG0616	signal peptide processing
D934_RS00425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D934_RS00440	COG2201	protein-glutamate methylesterase activity
D934_RS00445	COG2177	Part of the ABC transporter FtsEX involved in
D934_RS00450	COG2884	Cell division ATP-binding protein ftsE
D934_RS00460	COG3118	belongs to the thioredoxin family
D934_RS00465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D934_RS00475	COG0793	Belongs to the peptidase S41A family
D934_RS00480	COG4942	peptidase
D934_RS00495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D934_RS00500	COG0493	'glutamate synthase
D934_RS00505	COG0070	glutamate synthase
D934_RS00505	COG0069	glutamate synthase activity
D934_RS00505	COG0067	glutamate synthase
D934_RS00550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D934_RS00615	COG4942	peptidase
D934_RS00810	COG0187	DNA topoisomerase II activity
D934_RS00820	COG0501	Belongs to the peptidase M48B family
D934_RS00860	COG0408	coproporphyrinogen oxidase activity
D934_RS00885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D934_RS00955	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D934_RS00965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D934_RS00980	COG0511	ligase activity, forming carbon-carbon bonds
D934_RS00985	COG0439	Biotin carboxylase
D934_RS00990	COG0210	DNA helicase
D934_RS01020	COG1040	competence protein
D934_RS01030	COG1752	Esterase of the alpha-beta hydrolase superfamily
D934_RS01070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D934_RS01080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D934_RS01110	COG3121	Chaperone
D934_RS01115	COG3539	Fimbrial protein
D934_RS01120	COG1546	Belongs to the CinA family
D934_RS01125	COG0477	Major facilitator Superfamily
D934_RS01130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D934_RS01145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D934_RS01155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D934_RS01165	COG1534	Rna-binding protein
D934_RS01195	COG1560	Kdo2-lipid A biosynthetic process
D934_RS01200	COG1519	Transferase
D934_RS01215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D934_RS01240	COG1393	Belongs to the ArsC family
D934_RS01250	COG0367	asparagine synthase
D934_RS01260	COG2070	2-Nitropropane dioxygenase
D934_RS01275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D934_RS01290	COG0339	signal peptide processing
D934_RS01380	COG4221	oxidoreductase activity
D934_RS01400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D934_RS01410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D934_RS01460	COG2223	nitrite transmembrane transporter activity
D934_RS01470	COG0739	heme binding
D934_RS01505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D934_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
D934_RS01530	COG1272	protein, Hemolysin III
D934_RS01535	COG0463	Glycosyl transferase, family 2
D934_RS01540	COG0084	hydrolase, TatD family'
D934_RS01570	COG0330	HflC and HflK could
D934_RS01575	COG3956	TIGRFAM MazG family protein
D934_RS01580	COG1218	3'(2'),5'-bisphosphate nucleotidase
D934_RS01585	COG0494	nUDIX hydrolase
D934_RS01595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D934_RS01600	COG0513	Belongs to the DEAD box helicase family
D934_RS01605	COG0720	synthase
D934_RS01630	COG1981	membrane
D934_RS01665	COG0512	Glutamine amidotransferase of anthranilate synthase
D934_RS01695	COG0006	proline dipeptidase activity
D934_RS01715	COG1862	Preprotein translocase
D934_RS01720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D934_RS01725	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D934_RS01735	COG0617	tRNA 3'-terminal CCA addition
D934_RS01745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D934_RS01775	COG0195	Participates in both transcription termination and antitermination
D934_RS01805	COG1733	regulation of RNA biosynthetic process
D934_RS01860	COG2086	electron transfer activity
D934_RS01890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D934_RS01925	COG0477	Major facilitator Superfamily
D934_RS01945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D934_RS01950	COG0671	phosphoesterase, PA-phosphatase related
D934_RS01960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D934_RS01965	COG0628	permease
D934_RS01985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D934_RS01990	COG1090	epimerase
D934_RS01995	COG0318	PFAM AMP-dependent synthetase and ligase
D934_RS02015	COG1049	propionate catabolic process, 2-methylcitrate cycle
D934_RS02045	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D934_RS02085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D934_RS02115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D934_RS02125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D934_RS02135	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
D934_RS02140	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D934_RS02145	COG1034	ATP synthesis coupled electron transport
D934_RS02180	COG1007	ATP synthesis coupled electron transport
D934_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
D934_RS02190	COG2851	Citrate transporter
D934_RS02205	COG0642	Histidine kinase
D934_RS02225	COG2205	protein histidine kinase activity
D934_RS02225	COG0784	Response regulator, receiver
D934_RS02240	COG0281	malic enzyme
D934_RS02240	COG0280	phosphate acetyltransferase
D934_RS02250	COG0742	ribosomal rna small subunit methyltransferase
D934_RS02265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D934_RS02285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D934_RS02310	COG2166	iron-sulfur cluster assembly
D934_RS02340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D934_RS02420	COG1321	iron dependent repressor
D934_RS02425	COG1914	H( )-stimulated, divalent metal cation uptake system
D934_RS02440	COG1946	Acyl-CoA thioesterase
D934_RS02510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D934_RS02535	COG0575	Belongs to the CDS family
D934_RS02540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D934_RS02570	COG0528	UMP kinase activity
D934_RS02595	COG0800	Aldolase
D934_RS02615	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D934_RS02625	COG0354	folic acid binding
D934_RS02635	COG2009	succinate dehydrogenase
D934_RS02640	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D934_RS02650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D934_RS02675	COG0658	competence protein
D934_RS02675	COG2333	competence protein COMEC
D934_RS02680	COG0811	peptide transport
D934_RS02755	COG3077	Addiction module antitoxin, RelB DinJ family
D934_RS02760	COG3041	Addiction module toxin RelE StbE family
D934_RS02840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D934_RS02880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D934_RS02880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D934_RS02900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D934_RS02910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D934_RS02915	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
D934_RS02935	COG1024	Enoyl-CoA hydratase
D934_RS02940	COG0527	aspartate kinase activity
D934_RS02960	COG0494	nUDIX hydrolase
D934_RS02965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D934_RS02975	COG0424	maF-like protein
D934_RS02990	COG0312	modulator of DNA gyrase
D934_RS03000	COG0312	modulator of DNA gyrase
D934_RS03005	COG0583	DNA-binding transcription factor activity
D934_RS03020	COG1064	alcohol dehydrogenase
D934_RS03080	COG0356	it plays a direct role in the translocation of protons across the membrane
D934_RS03095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D934_RS03180	COG0201	protein transport
D934_RS03210	COG2960	long-chain fatty acid transporting porin activity
D934_RS03215	COG0606	chelatase, subunit chli
D934_RS03235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D934_RS03260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D934_RS03300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D934_RS03305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D934_RS03345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D934_RS03350	COG0625	glutathione transferase activity
D934_RS03360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D934_RS03365	COG1217	gtp-binding protein TYPA
D934_RS03390	COG0842	Transport permease protein
D934_RS03395	COG1131	(ABC) transporter
D934_RS03415	COG1643	Atp-dependent helicase
D934_RS03425	COG1956	GAF domain-containing protein
D934_RS03430	COG0729	surface antigen
D934_RS03435	COG2911	Protein conserved in bacteria
D934_RS03520	COG0668	transmembrane transport
D934_RS03555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D934_RS03580	COG2733	membrane
D934_RS03585	COG1253	flavin adenine dinucleotide binding
D934_RS03640	COG2840	Smr protein MutS2
D934_RS03655	COG0644	oxidoreductase
D934_RS03655	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D934_RS03670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D934_RS03670	COG3218	ABC-type transport auxiliary lipoprotein component
D934_RS03675	COG1127	ABC transporter
D934_RS03680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D934_RS03705	COG1077	Cell shape determining protein MreB Mrl
D934_RS03710	COG1792	Involved in formation and maintenance of cell shape
D934_RS03715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D934_RS03720	COG0768	penicillin binding
D934_RS03725	COG0772	Belongs to the SEDS family
D934_RS03735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D934_RS03755	COG2894	cell division
D934_RS03780	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D934_RS03795	COG2353	YceI-like domain
D934_RS03865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D934_RS03870	COG4208	sulfate ABC transporter
D934_RS03895	COG1846	Transcriptional regulator
D934_RS03925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D934_RS03935	COG0741	lytic transglycosylase activity
D934_RS03965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D934_RS04000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D934_RS04010	COG0514	ATP-dependent DNA helicase (RecQ)
D934_RS04015	COG0783	Belongs to the Dps family
D934_RS04020	COG1643	Atp-dependent helicase
D934_RS04140	COG3772	lysozyme
D934_RS04245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D934_RS04250	COG1845	cytochrome c oxidase, subunit III
D934_RS04255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D934_RS04260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D934_RS04265	COG0142	geranyltranstransferase activity
D934_RS04275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D934_RS04295	COG2239	Acts as a magnesium transporter
D934_RS04305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D934_RS04340	COG1137	ATPase activity
D934_RS04355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D934_RS04365	COG0271	Belongs to the BolA IbaG family
D934_RS04405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D934_RS04415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D934_RS04420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D934_RS04450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D934_RS04480	COG0542	response to heat
D934_RS04500	COG0492	ferredoxin-NADP+ reductase activity
D934_RS04520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D934_RS04535	COG4191	Histidine kinase
D934_RS04540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D934_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
D934_RS04575	COG1609	Transcriptional regulator
D934_RS04580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D934_RS04585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D934_RS04590	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D934_RS04600	COG0726	polysaccharide deacetylase
D934_RS04605	COG0297	glycogen (starch) synthase activity
D934_RS04620	COG0719	Fe-S assembly protein
D934_RS04625	COG0396	ATPase activity
D934_RS04630	COG0719	Fe-S assembly protein
D934_RS04635	COG1959	2 iron, 2 sulfur cluster binding
D934_RS04820	COG3772	lysozyme
D934_RS04855	COG4197	protein conserved in bacteria, prophage-related
D934_RS04935	COG3617	BRO family, N-terminal domain
D934_RS05005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D934_RS05010	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D934_RS05015	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D934_RS05030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D934_RS05055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D934_RS05055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D934_RS05075	COG0488	(ABC) transporter
D934_RS05110	COG1918	ferrous iron import across plasma membrane
D934_RS05110	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D934_RS05120	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D934_RS05145	COG0758	DNA mediated transformation
D934_RS05195	COG2969	positive regulation of protein catabolic process
D934_RS05200	COG0625	glutathione transferase activity
D934_RS05205	COG2857	Cytochrome c1
D934_RS05210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D934_RS05220	COG0741	lytic transglycosylase activity
D934_RS05230	COG1702	phosphate starvation-inducible protein PhoH
D934_RS05245	COG4535	Mg2 and Co2 transporter CorC
D934_RS05255	COG0598	Magnesium transport protein CorA
D934_RS05370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D934_RS05375	COG0277	FAD linked oxidase domain protein
D934_RS05380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D934_RS05385	COG0531	amino acid
D934_RS05390	COG0531	amino acid
D934_RS05440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D934_RS05475	COG0527	aspartate kinase activity
D934_RS05475	COG0460	homoserine dehydrogenase
D934_RS05495	COG1686	Belongs to the peptidase S11 family
D934_RS05520	COG4953	penicillin-binding protein 1C
D934_RS05545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D934_RS05565	COG0571	ribonuclease III activity
D934_RS05610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D934_RS05615	COG1506	peptidase
D934_RS05615	COG0823	Involved in the tonB-independent uptake of proteins
D934_RS05620	COG1297	OPT oligopeptide transporter protein
D934_RS05645	COG0676	glucose-6-phosphate 1-epimerase activity
D934_RS05655	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D934_RS05660	COG1335	isochorismatase
D934_RS05665	COG0318	PFAM AMP-dependent synthetase and ligase
D934_RS05675	COG0463	Glycosyl transferase, family 2
D934_RS05690	COG1192	Involved in chromosome partitioning
D934_RS05845	COG3617	BRO family, N-terminal domain
D934_RS05860	COG3772	lysozyme
D934_RS05935	COG3093	addiction module antidote protein HigA
D934_RS06010	COG0629	single-stranded DNA binding
D934_RS06040	COG5532	Uncharacterized conserved protein (DUF2303)
D934_RS06100	COG4197	protein conserved in bacteria, prophage-related
D934_RS06120	COG3617	BRO family, N-terminal domain
D934_RS06125	COG3617	BRO family, N-terminal domain
D934_RS06140	COG0305	Participates in initiation and elongation during chromosome replication
D934_RS06155	COG3772	lysozyme
D934_RS06180	COG5410	chromosome segregation
D934_RS06200	COG2369	cell adhesion
D934_RS06300	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_RS06305	COG3657	addiction module killer protein
D934_RS06335	COG1131	(ABC) transporter
D934_RS06340	COG0386	Belongs to the glutathione peroxidase family
D934_RS06370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D934_RS06395	COG2226	methyltransferase
D934_RS06415	COG0400	carboxylic ester hydrolase activity
D934_RS06420	COG3275	phosphorelay sensor kinase activity
D934_RS06475	COG0463	Glycosyl transferase, family 2
D934_RS06485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D934_RS06500	COG0392	lysyltransferase activity
D934_RS06500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D934_RS06505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D934_RS06535	COG3617	BRO family, N-terminal domain
D934_RS06620	COG3772	lysozyme
D934_RS06715	COG0251	oxidation-reduction process
D934_RS06730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D934_RS06745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D934_RS06760	COG4969	Belongs to the N-Me-Phe pilin family
D934_RS06790	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D934_RS06820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D934_RS06860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D934_RS06875	COG0537	adenosine 5'-monophosphoramidase activity
D934_RS06895	COG0714	Associated with various cellular activities
D934_RS06905	COG1399	metal-binding, possibly nucleic acid-binding protein
D934_RS06910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D934_RS06915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D934_RS06950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D934_RS06955	COG1764	response to oxidative stress
D934_RS06960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D934_RS07015	COG2353	YceI-like domain
D934_RS07030	COG0347	Belongs to the P(II) protein family
D934_RS07050	COG2204	response regulator
D934_RS07055	COG3852	Histidine kinase
D934_RS07140	COG0629	single-stranded DNA binding
D934_RS07155	COG4969	Belongs to the N-Me-Phe pilin family
D934_RS07235	COG0358	DNA primase activity
D934_RS07260	COG0740	serine-type endopeptidase activity
D934_RS07275	COG3772	lysozyme
D934_RS07315	COG5449	Phage conserved hypothetical protein BR0599
D934_RS07430	COG2193	ferroxidase activity
D934_RS07465	COG0861	Integral membrane protein TerC family
D934_RS07470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D934_RS07475	COG0531	amino acid
D934_RS07485	COG1116	anion transmembrane transporter activity
D934_RS07500	COG2853	Lipoprotein
D934_RS07520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D934_RS07525	COG1127	ABC transporter
D934_RS07530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D934_RS07535	COG1074	ATP-dependent DNA helicase activity
D934_RS07580	COG0358	DNA primase activity
D934_RS07590	COG1610	YqeY-like protein
D934_RS07605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D934_RS07610	COG0668	transmembrane transport
D934_RS07630	COG1183	phosphatidylcholine synthase activity
D934_RS07660	COG0604	alcohol dehydrogenase
D934_RS07665	COG0330	HflC and HflK could
D934_RS07670	COG0330	HflC and HflK could
D934_RS07685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D934_RS07715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D934_RS07725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D934_RS07730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D934_RS07735	COG1611	Belongs to the LOG family
D934_RS07785	COG0629	single-stranded DNA binding
D934_RS07810	COG5532	Uncharacterized conserved protein (DUF2303)
D934_RS07895	COG3617	BRO family, N-terminal domain
D934_RS07910	COG0305	Participates in initiation and elongation during chromosome replication
D934_RS07935	COG3772	lysozyme
D934_RS07960	COG5410	chromosome segregation
D934_RS07980	COG2369	cell adhesion
D934_RS08080	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_RS08085	COG3657	addiction module killer protein
D934_RS08130	COG4206	TonB-dependent receptor
D934_RS08150	COG0277	FAD linked oxidase domain protein
D934_RS08155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D934_RS08165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D934_RS08185	COG0305	Participates in initiation and elongation during chromosome replication
D934_RS08200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D934_RS08205	COG0667	Aldo Keto reductase
D934_RS08245	COG2194	sulfuric ester hydrolase activity
D934_RS08255	COG0352	thiamine-phosphate diphosphorylase activity
D934_RS08290	COG0629	single-stranded DNA binding
D934_RS08305	COG4969	Belongs to the N-Me-Phe pilin family
D934_RS08385	COG0358	DNA primase activity
D934_RS08410	COG0740	serine-type endopeptidase activity
D934_RS08425	COG3772	lysozyme
D934_RS08465	COG5449	Phage conserved hypothetical protein BR0599
D934_RS08605	COG2337	Toxic component of a toxin-antitoxin (TA) module
D934_RS08780	COG0406	alpha-ribazole phosphatase activity
D934_RS08800	COG0386	Belongs to the glutathione peroxidase family
D934_RS08820	COG0602	queuosine metabolic process
D934_RS08830	COG2885	chlorophyll binding
D934_RS08855	COG0824	Thioesterase
D934_RS08895	COG0552	protein localization to endoplasmic reticulum
D934_RS08910	COG0084	hydrolase, TatD family'
D934_RS08950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D934_RS09000	COG2091	lysine biosynthetic process via aminoadipic acid
D934_RS09010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D934_RS09015	COG1301	dicarboxylic acid transport
D934_RS09035	COG0339	signal peptide processing
D934_RS09045	COG0285	dihydrofolate synthase activity
D934_RS09075	COG0643	Histidine kinase
D934_RS09075	COG2198	Histidine kinase
D934_RS09075	COG0784	Response regulator, receiver
D934_RS09080	COG0840	transmembrane signaling receptor activity
D934_RS09125	COG0727	PFAM Uncharacterised protein family (UPF0153)
D934_RS09130	COG0596	Alpha beta hydrolase
D934_RS09150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D934_RS09160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D934_RS09165	COG0138	bifunctional purine biosynthesis protein purh
D934_RS09180	COG1289	transmembrane transporter activity
D934_RS09185	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D934_RS09200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D934_RS09210	COG0557	exoribonuclease II activity
D934_RS09220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D934_RS09225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D934_RS09260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D934_RS09290	COG0778	Nitroreductase
D934_RS09300	COG0006	proline dipeptidase activity
D934_RS09320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D934_RS09340	COG0025	NhaP-type Na H and K H
D934_RS09355	COG2925	Exonuclease
D934_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
D934_RS09415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D934_RS09470	COG4962	Type ii secretion system protein e
D934_RS09500	COG2902	Dehydrogenase
D934_RS09510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D934_RS09620	COG2850	peptidyl-arginine hydroxylation
D934_RS09625	COG0567	Dehydrogenase, E1 component
D934_RS09650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D934_RS09710	COG0583	DNA-binding transcription factor activity
D934_RS09715	COG3634	alkyl hydroperoxide reductase activity
D934_RS09730	COG1450	Type ii and iii secretion system protein
D934_RS09745	COG3166	PFAM Fimbrial assembly family protein
D934_RS09750	COG3156	type II secretion system protein K
D934_RS09755	COG4795	General secretion pathway protein
D934_RS09760	COG2165	general secretion pathway protein
D934_RS09765	COG4970	Tfp pilus assembly protein FimT
D934_RS09770	COG2165	general secretion pathway protein
D934_RS09775	COG1459	type II secretion system
D934_RS09780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D934_RS09785	COG5295	Hep Hag repeat protein
D934_RS09820	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D934_RS09835	COG1561	YicC-like family, N-terminal region
D934_RS09845	COG1758	RNA polymerase activity
D934_RS09860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D934_RS09915	COG0308	aminopeptidase N
D934_RS09965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D934_RS10010	COG0489	protein tyrosine kinase activity
D934_RS10020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D934_RS10070	COG2267	carboxylic ester hydrolase activity
D934_RS10090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D934_RS10145	COG0077	Prephenate dehydratase
D934_RS10145	COG1605	Chorismate mutase
D934_RS10160	COG1668	transmembrane transport
D934_RS10165	COG4555	ABC transporter
D934_RS10190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D934_RS10200	COG1605	Chorismate mutase
D934_RS10200	COG0287	Prephenate dehydrogenase
D934_RS10205	COG0484	heat shock protein binding
D934_RS10235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D934_RS10260	COG1278	Cold shock
D934_RS10270	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D934_RS10280	COG2954	triphosphatase activity
D934_RS10295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D934_RS10300	COG0438	transferase activity, transferring glycosyl groups
D934_RS10315	COG0438	transferase activity, transferring glycosyl groups
D934_RS10375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D934_RS10380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D934_RS10395	COG1064	alcohol dehydrogenase
D934_RS10415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D934_RS10425	COG0436	Aminotransferase
D934_RS10515	COG0196	riboflavin kinase activity
D934_RS10520	COG0728	peptidoglycan biosynthetic process
D934_RS10525	COG0268	Binds directly to 16S ribosomal RNA
D934_RS10545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D934_RS10575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D934_RS10590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D934_RS10640	COG0395	ABC-type sugar transport system, permease component
D934_RS10645	COG1175	transmembrane transport
D934_RS10670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D934_RS10690	COG0436	Aminotransferase
D934_RS10745	COG5434	Belongs to the glycosyl hydrolase 28 family
D934_RS10765	COG0402	S-adenosylhomocysteine deaminase activity
D934_RS10775	COG1509	lysine 2,3-aminomutase activity
D934_RS10810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D934_RS10815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D934_RS10830	COG1028	Short-chain dehydrogenase reductase Sdr
D934_RS10875	COG0142	geranyltranstransferase activity
D934_RS10895	COG1301	dicarboxylic acid transport
D934_RS10905	COG0791	NLP P60 protein
D934_RS10910	COG0791	NLP P60 protein
D934_RS10920	COG2311	Membrane
D934_RS10930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D934_RS10980	COG0351	phosphomethylpyrimidine kinase
D934_RS10980	COG0352	thiamine-phosphate diphosphorylase activity
D934_RS10990	COG1324	tolerance protein
D934_RS11000	COG0459	protein refolding
D934_RS11030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D934_RS11035	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
D934_RS11050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D934_RS11070	COG4774	siderophore transport
D934_RS11095	COG1477	protein flavinylation
D934_RS11100	COG1555	photosystem II stabilization
D934_RS11105	COG3178	'Phosphotransferase
D934_RS11110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D934_RS11120	COG0628	permease
D934_RS11135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D934_RS11155	COG3590	peptidase
D934_RS11200	COG0805	protein transport
D934_RS11215	COG0519	Catalyzes the synthesis of GMP from XMP
D934_RS11215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D934_RS11225	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D934_RS11245	COG3107	peptidoglycan biosynthetic process
D934_RS11265	COG2878	Part of a membrane complex involved in electron transport
D934_RS11325	COG0358	DNA primase activity
D934_RS11345	COG4197	protein conserved in bacteria, prophage-related
D934_RS11405	COG4969	Belongs to the N-Me-Phe pilin family
D934_RS11420	COG0629	single-stranded DNA binding
D934_RS11475	COG3657	addiction module killer protein
D934_RS11480	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_RS11525	COG3657	addiction module killer protein
D934_RS11530	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D934_RS11585	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D934_RS11590	COG0488	(ABC) transporter
D934_RS11610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D934_RS11610	COG4651	solute:proton antiporter activity
D934_RS11640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D934_RS11670	COG0859	PFAM glycosyl transferase family 9
D934_RS11685	COG0631	protein serine/threonine phosphatase activity
D934_RS11690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D934_RS11695	COG0328	RNA-DNA hybrid ribonuclease activity
D934_RS11710	COG2183	response to ionizing radiation
D934_RS11725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D934_RS11730	COG3118	belongs to the thioredoxin family
D934_RS11775	COG2951	lytic endotransglycosylase activity
D934_RS11865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D934_RS11875	COG1199	ATP-dependent helicase activity
D934_RS11885	COG0288	reversible hydration of carbon dioxide
D934_RS11905	COG2011	ABC-type metal ion transport system permease component
D934_RS11920	COG0508	dehydrogenase complex catalyzes the overall conversion of
D934_RS11925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D934_RS11935	COG0626	cystathionine gamma-synthase activity
D934_RS11940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D934_RS11945	COG0739	heme binding
D934_RS11965	COG1238	metal cluster binding
D934_RS11980	COG5002	protein histidine kinase activity
D934_RS12000	COG3858	chitin binding
D934_RS12000	COG1388	LysM domain
D934_RS12005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D934_RS12015	COG1472	Belongs to the glycosyl hydrolase 3 family
D934_RS12030	COG3537	Alpha-1,2-mannosidase
D934_RS12055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D934_RS12060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D934_RS12100	COG0469	pyruvate kinase activity
D934_RS12115	COG0735	belongs to the Fur family
D934_RS12125	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D934_RS12125	COG5297	Belongs to the glycosyl hydrolase family 6
D934_RS12135	COG0612	Peptidase, M16
D934_RS12150	COG4305	rare lipoprotein A
D934_RS12160	COG0739	heme binding
D934_RS12170	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D934_RS12175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D934_RS12185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D934_RS12215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D934_RS12230	COG3116	cell division
D934_RS12245	COG0471	metal ion transport
D934_RS12245	COG3273	potassium ion transport
D934_RS12295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D934_RS12360	COG0860	N-Acetylmuramoyl-L-alanine amidase
D934_RS12365	COG0802	atpase or kinase
D934_RS12370	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D934_RS12370	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D934_RS12445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D934_RS12470	COG0745	RESPONSE REGULATOR receiver
D934_RS12475	COG0642	Histidine kinase
D934_RS12485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D934_RS12535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D934_RS12545	COG2831	hemolysin activation secretion protein
D934_RS12570	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D934_RS12610	COG0316	Belongs to the HesB IscA family
D934_RS12645	COG0697	spore germination
D934_RS12650	COG0671	phosphoesterase, PA-phosphatase related
D934_RS12655	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D934_RS12665	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
D934_RS12685	COG1132	(ABC) transporter
D934_RS12695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins