locus-tag	class	description
GT347_RS00040	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS00050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GT347_RS00060	COG0156	8-amino-7-oxononanoate synthase activity
GT347_RS00070	COG2183	response to ionizing radiation
GT347_RS00080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT347_RS00080	COG0475	glutathione-regulated potassium exporter activity
GT347_RS00120	COG0411	ABC transporter
GT347_RS00190	COG0716	FMN binding
GT347_RS00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS00220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GT347_RS00240	COG0583	DNA-binding transcription factor activity
GT347_RS00245	COG0436	Aminotransferase
GT347_RS00260	COG0584	glycerophosphoryl diester phosphodiesterase
GT347_RS00265	COG0789	Transcriptional regulator
GT347_RS00285	COG0587	DNA-directed DNA polymerase activity
GT347_RS00300	COG1132	(ABC) transporter
GT347_RS00310	COG0642	Histidine kinase
GT347_RS00315	COG0745	RESPONSE REGULATOR receiver
GT347_RS00335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GT347_RS00345	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GT347_RS00345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS00350	COG0840	transmembrane signaling receptor activity
GT347_RS00365	COG0175	sulfate reduction
GT347_RS00375	COG2895	sulfate adenylyltransferase (ATP) activity
GT347_RS00380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GT347_RS00385	COG0492	ferredoxin-NADP+ reductase activity
GT347_RS00400	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS00420	COG1609	Transcriptional regulator
GT347_RS00430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS00435	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS00440	COG1960	acyl-CoA dehydrogenase activity
GT347_RS00450	COG3622	Belongs to the hyi family
GT347_RS00455	COG3395	kinase activity
GT347_RS00475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT347_RS00485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS00525	COG1476	TRANSCRIPTIONal
GT347_RS00545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT347_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT347_RS00570	COG2066	Belongs to the glutaminase family
GT347_RS00580	COG2918	glutathione biosynthetic process
GT347_RS00590	COG0400	carboxylic ester hydrolase activity
GT347_RS00630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_RS00630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_RS00645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GT347_RS00650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT347_RS00655	COG0436	Aminotransferase
GT347_RS00675	COG0824	Thioesterase
GT347_RS00685	COG0848	biopolymer transport protein
GT347_RS00705	COG3791	Glutathione-dependent formaldehyde-activating
GT347_RS00710	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GT347_RS00720	COG1011	Hydrolase
GT347_RS00735	COG3264	Mechanosensitive ion channel
GT347_RS00735	COG1196	nuclear chromosome segregation
GT347_RS00740	COG0628	permease
GT347_RS00770	COG0840	transmembrane signaling receptor activity
GT347_RS00780	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GT347_RS00800	COG1845	cytochrome c oxidase, subunit III
GT347_RS00805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GT347_RS00810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT347_RS00815	COG0477	Major facilitator Superfamily
GT347_RS00840	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS00845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS00855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS00865	COG2801	Transposase and inactivated derivatives
GT347_RS00865	COG3415	Transposase
GT347_RS00880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS00885	COG2354	Protein conserved in bacteria
GT347_RS00890	COG0047	phosphoribosylformylglycinamidine synthase activity
GT347_RS00890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GT347_RS00895	COG0024	Methionine aminopeptidase
GT347_RS00910	COG2186	Transcriptional regulator
GT347_RS00945	COG0765	amino acid transport
GT347_RS00950	COG4597	amino acid ABC transporter
GT347_RS00960	COG0242	peptide deformylase activity
GT347_RS00985	COG1196	nuclear chromosome segregation
GT347_RS01000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT347_RS01005	COG0058	SHG alpha-glucan phosphorylase activity
GT347_RS01010	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS01015	COG0436	Aminotransferase
GT347_RS01025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_RS01030	COG2890	protein-(glutamine-N5) methyltransferase activity
GT347_RS01055	COG3415	Transposase
GT347_RS01055	COG2801	Transposase and inactivated derivatives
GT347_RS01070	COG4191	Histidine kinase
GT347_RS01075	COG3920	Histidine kinase
GT347_RS01080	COG4566	intracellular signal transduction
GT347_RS01085	COG4566	intracellular signal transduction
GT347_RS01125	COG1116	anion transmembrane transporter activity
GT347_RS01140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS01145	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS01150	COG1802	Transcriptional regulator
GT347_RS01175	COG1335	isochorismatase
GT347_RS01180	COG2175	clavaminate synthase activity
GT347_RS01185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GT347_RS01190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS01265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GT347_RS01290	COG5002	protein histidine kinase activity
GT347_RS01300	COG0745	RESPONSE REGULATOR receiver
GT347_RS01375	COG0037	tRNA processing
GT347_RS01380	COG0825	malonyl-CoA metabolic process
GT347_RS01390	COG0215	cysteine-tRNA ligase activity
GT347_RS01405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GT347_RS01415	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_RS01435	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS01440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT347_RS01450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_RS01475	COG1196	nuclear chromosome segregation
GT347_RS01490	COG1752	Esterase of the alpha-beta hydrolase superfamily
GT347_RS01510	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GT347_RS01515	COG5001	Diguanylate cyclase
GT347_RS01515	COG3300	MHYT domain
GT347_RS01555	COG0583	DNA-binding transcription factor activity
GT347_RS01560	COG0693	protein deglycase activity
GT347_RS01580	COG0612	Peptidase, M16
GT347_RS01585	COG0519	Catalyzes the synthesis of GMP from XMP
GT347_RS01585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GT347_RS01605	COG2867	negative regulation of translational initiation
GT347_RS01610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GT347_RS01615	COG0154	amidase activity
GT347_RS01620	COG1126	abc transporter atp-binding protein
GT347_RS01625	COG1137	ATPase activity
GT347_RS01635	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS01675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GT347_RS01680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GT347_RS01685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GT347_RS01690	COG0195	Participates in both transcription termination and antitermination
GT347_RS01690	COG2251	uridine kinase activity
GT347_RS01695	COG0779	Required for maturation of 30S ribosomal subunits
GT347_RS01705	COG4172	Belongs to the ABC transporter superfamily
GT347_RS01710	COG4239	(ABC) transporter, permease
GT347_RS01715	COG4174	ABC transporter (Permease)
GT347_RS01725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GT347_RS01730	COG1793	dna ligase
GT347_RS01800	COG2204	response regulator
GT347_RS01815	COG1280	lysine exporter protein (LysE YggA)
GT347_RS01830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_RS01840	COG2207	Transcriptional regulator
GT347_RS01850	COG0657	acetylesterase activity
GT347_RS01855	COG0235	Class ii aldolase
GT347_RS01865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GT347_RS01875	COG0183	Belongs to the thiolase family
GT347_RS01885	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS01940	COG1960	acyl-CoA dehydrogenase activity
GT347_RS01945	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GT347_RS01975	COG0724	RNA recognition motif
GT347_RS01980	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GT347_RS01985	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GT347_RS01990	COG1414	Transcriptional regulator
GT347_RS01995	COG0583	DNA-binding transcription factor activity
GT347_RS02020	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS02030	COG0840	transmembrane signaling receptor activity
GT347_RS02060	COG2200	EAL domain
GT347_RS02060	COG3287	FIST C domain
GT347_RS02060	COG2199	diguanylate cyclase activity
GT347_RS02085	COG0642	Histidine kinase
GT347_RS02090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GT347_RS02115	COG0076	glutamate decarboxylase activity
GT347_RS02120	COG2982	Protein involved in outer membrane biogenesis
GT347_RS02135	COG1643	Atp-dependent helicase
GT347_RS02140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT347_RS02140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GT347_RS02145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GT347_RS02155	COG4208	sulfate ABC transporter
GT347_RS02160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GT347_RS02165	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GT347_RS02170	COG0450	alkyl hydroperoxide reductase
GT347_RS02185	COG1183	phosphatidylcholine synthase activity
GT347_RS02195	COG0440	acetolactate synthase activity
GT347_RS02200	COG0028	Belongs to the TPP enzyme family
GT347_RS02225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GT347_RS02235	COG0347	Belongs to the P(II) protein family
GT347_RS02245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GT347_RS02260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GT347_RS02265	COG0746	molybdenum cofactor guanylyltransferase activity
GT347_RS02270	COG0328	RNA-DNA hybrid ribonuclease activity
GT347_RS02275	COG2226	methyltransferase
GT347_RS02280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT347_RS02285	COG1388	LysM domain
GT347_RS02285	COG0741	lytic transglycosylase activity
GT347_RS02295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS02380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GT347_RS02410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GT347_RS02415	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GT347_RS02425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GT347_RS02445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GT347_RS02450	COG0028	Belongs to the TPP enzyme family
GT347_RS02455	COG0254	rRNA binding
GT347_RS02465	COG0534	Mate efflux family protein
GT347_RS02485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT347_RS02490	COG0581	inorganic phosphate transmembrane transporter activity
GT347_RS02495	COG0573	inorganic phosphate transmembrane transporter activity
GT347_RS02500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GT347_RS02530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GT347_RS02535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GT347_RS02540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT347_RS02545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GT347_RS02550	COG1534	Rna-binding protein
GT347_RS02565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT347_RS02575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GT347_RS02580	COG0505	Belongs to the CarA family
GT347_RS02585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT347_RS02590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GT347_RS02595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_RS02600	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_RS02605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GT347_RS02610	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GT347_RS02625	COG0750	zinc metalloprotease
GT347_RS02630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GT347_RS02635	COG0575	Belongs to the CDS family
GT347_RS02645	COG0233	cytoplasmic translational termination
GT347_RS02650	COG0528	UMP kinase activity
GT347_RS02655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GT347_RS02660	COG0052	Belongs to the universal ribosomal protein uS2 family
GT347_RS02665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GT347_RS02685	COG0557	exoribonuclease II activity
GT347_RS02695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT347_RS02740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GT347_RS02775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT347_RS02785	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS02795	COG0745	RESPONSE REGULATOR receiver
GT347_RS02805	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GT347_RS02805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GT347_RS02810	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GT347_RS02810	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GT347_RS02815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GT347_RS02820	COG0560	Phosphoserine phosphatase
GT347_RS02835	COG0583	DNA-binding transcription factor activity
GT347_RS02840	COG1304	FMN binding
GT347_RS02865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GT347_RS02870	COG0513	Belongs to the DEAD box helicase family
GT347_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS02895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GT347_RS02920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GT347_RS02935	COG4977	sequence-specific DNA binding
GT347_RS02955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GT347_RS02965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GT347_RS02985	COG1492	cobalamin metabolic process
GT347_RS03000	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GT347_RS03005	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GT347_RS03010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GT347_RS03015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GT347_RS03020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GT347_RS03035	COG4206	TonB-dependent receptor
GT347_RS03060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GT347_RS03065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GT347_RS03090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS03105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT347_RS03125	COG1802	Transcriptional regulator
GT347_RS03145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT347_RS03155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS03160	COG2205	protein histidine kinase activity
GT347_RS03165	COG0745	RESPONSE REGULATOR receiver
GT347_RS03170	COG0840	transmembrane signaling receptor activity
GT347_RS03230	COG2080	2 iron, 2 sulfur cluster binding
GT347_RS03235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT347_RS03240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_RS03245	COG2951	lytic endotransglycosylase activity
GT347_RS03265	COG0628	permease
GT347_RS03280	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
GT347_RS03290	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GT347_RS03295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GT347_RS03300	COG3639	organic phosphonate transmembrane transporter activity
GT347_RS03305	COG3639	organic phosphonate transmembrane transporter activity
GT347_RS03325	COG2203	Gaf domain
GT347_RS03325	COG3706	GGDEF domain
GT347_RS03325	COG4251	negative regulation of phosphorylation
GT347_RS03325	COG5001	Diguanylate cyclase
GT347_RS03330	COG0745	RESPONSE REGULATOR receiver
GT347_RS03345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GT347_RS03355	COG2885	chlorophyll binding
GT347_RS03360	COG0823	Involved in the tonB-independent uptake of proteins
GT347_RS03365	COG1132	(ABC) transporter
GT347_RS03375	COG1530	ribonuclease E activity
GT347_RS03380	COG0424	maF-like protein
GT347_RS03385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GT347_RS03390	COG0799	negative regulation of ribosome biogenesis
GT347_RS03400	COG0408	coproporphyrinogen oxidase activity
GT347_RS03410	COG0217	transcriptional regulatory protein
GT347_RS03415	COG0433	COG0433 Predicted ATPase
GT347_RS03420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GT347_RS03425	COG1744	ABC transporter substrate-binding protein PnrA-like
GT347_RS03450	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS03490	COG3193	protein, possibly involved in utilization of glycolate and propanediol
GT347_RS03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GT347_RS03535	COG1414	Transcriptional regulator
GT347_RS03540	COG3706	GGDEF domain
GT347_RS03565	COG0583	DNA-binding transcription factor activity
GT347_RS03590	COG0346	lactoylglutathione lyase activity
GT347_RS03595	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GT347_RS03600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GT347_RS03635	COG0800	Aldolase
GT347_RS03640	COG0129	dihydroxy-acid dehydratase activity
GT347_RS03645	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GT347_RS03650	COG2032	superoxide dismutase activity
GT347_RS03660	COG0259	pyridoxamine-phosphate oxidase activity
GT347_RS03690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_RS03695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GT347_RS03720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GT347_RS03735	COG3657	addiction module killer protein
GT347_RS03755	COG2133	pyrroloquinoline quinone binding
GT347_RS03760	COG0791	NLP P60 protein
GT347_RS03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT347_RS03770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GT347_RS03775	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT347_RS03780	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GT347_RS03790	COG4566	intracellular signal transduction
GT347_RS03795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GT347_RS03810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GT347_RS03815	COG0167	dihydroorotate dehydrogenase activity
GT347_RS03825	COG0783	Belongs to the Dps family
GT347_RS03855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS03870	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GT347_RS03875	COG1074	ATP-dependent DNA helicase activity
GT347_RS03880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GT347_RS03895	COG0625	glutathione transferase activity
GT347_RS03900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT347_RS03900	COG1017	nitric oxide dioxygenase activity
GT347_RS03910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GT347_RS03920	COG0443	Heat shock 70 kDa protein
GT347_RS03930	COG0316	Belongs to the HesB IscA family
GT347_RS03935	COG0822	iron-sulfur transferase activity
GT347_RS03940	COG1104	cysteine desulfurase activity
GT347_RS03945	COG1959	2 iron, 2 sulfur cluster binding
GT347_RS03950	COG0556	nucleotide-excision repair
GT347_RS03965	COG2878	Part of a membrane complex involved in electron transport
GT347_RS03975	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS03980	COG2030	dehydratase
GT347_RS03990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS03995	COG1960	acyl-CoA dehydrogenase activity
GT347_RS04000	COG0427	acetyl-CoA hydrolase
GT347_RS04005	COG2301	Belongs to the HpcH HpaI aldolase family
GT347_RS04010	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS04015	COG2808	Putative FMN-binding domain
GT347_RS04020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS04025	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS04030	COG0154	amidase activity
GT347_RS04035	COG1414	Transcriptional regulator
GT347_RS04045	COG2814	Major facilitator Superfamily
GT347_RS04065	COG1595	DNA-templated transcription, initiation
GT347_RS04105	COG4651	solute:proton antiporter activity
GT347_RS04105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GT347_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS04115	COG0183	Belongs to the thiolase family
GT347_RS04120	COG3243	poly(R)-hydroxyalkanoic acid synthase
GT347_RS04150	COG2831	hemolysin activation secretion protein
GT347_RS04190	COG0625	glutathione transferase activity
GT347_RS04195	COG0667	Aldo Keto reductase
GT347_RS04220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GT347_RS04225	COG1570	exodeoxyribonuclease VII activity
GT347_RS04230	COG0811	peptide transport
GT347_RS04235	COG0848	biopolymer transport protein
GT347_RS04240	COG1663	tetraacyldisaccharide 4'-kinase activity
GT347_RS04245	COG2835	tetraacyldisaccharide 4'-kinase activity
GT347_RS04250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GT347_RS04275	COG0563	adenylate kinase activity
GT347_RS04280	COG0252	asparaginase activity
GT347_RS04285	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT347_RS04305	COG1024	Enoyl-CoA hydratase
GT347_RS04355	COG0667	Aldo Keto reductase
GT347_RS04390	COG2308	Evidence 4 Homologs of previously reported genes of
GT347_RS04415	COG0741	lytic transglycosylase activity
GT347_RS04420	COG0187	DNA topoisomerase II activity
GT347_RS04430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS04435	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
GT347_RS04440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GT347_RS04450	COG2850	peptidyl-arginine hydroxylation
GT347_RS04455	COG1047	Peptidyl-prolyl cis-trans
GT347_RS04465	COG0756	dUTP diphosphatase activity
GT347_RS04470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GT347_RS04475	COG0504	CTP synthase activity
GT347_RS04480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GT347_RS04490	COG0148	phosphopyruvate hydratase activity
GT347_RS04495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GT347_RS04520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GT347_RS04530	COG2833	Protein of unknown function (DUF455)
GT347_RS04540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GT347_RS04565	COG4974	Belongs to the 'phage' integrase family
GT347_RS04580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GT347_RS04585	COG0802	atpase or kinase
GT347_RS04590	COG0860	N-Acetylmuramoyl-L-alanine amidase
GT347_RS04600	COG0586	Pfam SNARE associated Golgi protein
GT347_RS04605	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GT347_RS04615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GT347_RS04620	COG1136	(ABC) transporter
GT347_RS04640	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS04655	COG0411	ABC transporter
GT347_RS04660	COG3237	CsbD-like
GT347_RS04670	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GT347_RS04675	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
GT347_RS04720	COG3158	transport of potassium into the cell
GT347_RS04745	COG0542	response to heat
GT347_RS04775	COG0297	glycogen (starch) synthase activity
GT347_RS04780	COG1640	4-alpha-glucanotransferase
GT347_RS04795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT347_RS04800	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GT347_RS04810	COG0617	tRNA 3'-terminal CCA addition
GT347_RS04820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT347_RS04830	COG0728	peptidoglycan biosynthetic process
GT347_RS04835	COG0268	Binds directly to 16S ribosomal RNA
GT347_RS04850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GT347_RS04855	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GT347_RS04860	COG2202	Pas domain
GT347_RS04860	COG2199	diguanylate cyclase activity
GT347_RS04860	COG2200	EAL domain
GT347_RS04890	COG1845	cytochrome c oxidase, subunit III
GT347_RS04900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GT347_RS04935	COG0437	4 iron, 4 sulfur cluster binding
GT347_RS04960	COG0308	aminopeptidase N
GT347_RS04965	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GT347_RS05005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_RS05035	COG0811	peptide transport
GT347_RS05080	COG1864	DNA RNA non-specific endonuclease
GT347_RS05080	COG3591	Belongs to the peptidase S1B family
GT347_RS05090	COG0583	DNA-binding transcription factor activity
GT347_RS05100	COG1309	transcriptional regulator
GT347_RS05110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_RS05115	COG0156	8-amino-7-oxononanoate synthase activity
GT347_RS05125	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS05135	COG1285	pathogenesis
GT347_RS05140	COG3046	protein related to deoxyribodipyrimidine photolyase
GT347_RS05145	COG0583	DNA-binding transcription factor activity
GT347_RS05150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_RS05165	COG0484	heat shock protein binding
GT347_RS05200	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS05235	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GT347_RS05240	COG2267	carboxylic ester hydrolase activity
GT347_RS05245	COG2205	protein histidine kinase activity
GT347_RS05245	COG0784	Response regulator, receiver
GT347_RS05260	COG0840	transmembrane signaling receptor activity
GT347_RS05265	COG2198	Histidine kinase
GT347_RS05265	COG0643	Histidine kinase
GT347_RS05270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS05285	COG0583	DNA-binding transcription factor activity
GT347_RS05300	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS05325	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS05330	COG2079	MmgE PrpD family protein
GT347_RS05335	COG0583	DNA-binding transcription factor activity
GT347_RS05350	COG0765	amino acid transport
GT347_RS05360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS05370	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS05385	COG0410	ABC transporter
GT347_RS05395	COG1414	Transcriptional regulator
GT347_RS05405	COG2301	Belongs to the HpcH HpaI aldolase family
GT347_RS05410	COG0427	acetyl-CoA hydrolase
GT347_RS05415	COG1024	Enoyl-CoA hydratase
GT347_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS05430	COG0318	PFAM AMP-dependent synthetase and ligase
GT347_RS05435	COG2188	Transcriptional regulator
GT347_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS05510	COG0583	DNA-binding transcription factor activity
GT347_RS05520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT347_RS05530	COG0583	DNA-binding transcription factor activity
GT347_RS05535	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS05545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS05570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GT347_RS05580	COG0835	chemotaxis
GT347_RS05585	COG0840	transmembrane signaling receptor activity
GT347_RS05590	COG0643	Histidine kinase
GT347_RS05590	COG2198	Histidine kinase
GT347_RS05600	COG2201	protein-glutamate methylesterase activity
GT347_RS05605	COG0840	transmembrane signaling receptor activity
GT347_RS05615	COG2814	Major facilitator Superfamily
GT347_RS05620	COG0583	DNA-binding transcription factor activity
GT347_RS05625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GT347_RS05675	COG0589	response to stress
GT347_RS05690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GT347_RS05695	COG0724	RNA recognition motif
GT347_RS05705	COG0459	protein refolding
GT347_RS05730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GT347_RS05745	COG1063	alcohol dehydrogenase
GT347_RS05770	COG4191	Histidine kinase
GT347_RS05770	COG2205	protein histidine kinase activity
GT347_RS05770	COG0745	RESPONSE REGULATOR receiver
GT347_RS05780	COG0024	Methionine aminopeptidase
GT347_RS05795	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS05805	COG0583	DNA-binding transcription factor activity
GT347_RS05840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_RS05855	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS05860	COG2186	Transcriptional regulator
GT347_RS05885	COG0243	molybdopterin cofactor binding
GT347_RS05895	COG0642	Histidine kinase
GT347_RS05900	COG0745	RESPONSE REGULATOR receiver
GT347_RS05910	COG2814	Major facilitator Superfamily
GT347_RS05915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS05945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_RS05950	COG0066	3-isopropylmalate dehydratase activity
GT347_RS06010	COG1902	pentaerythritol trinitrate reductase activity
GT347_RS06015	COG0154	amidase activity
GT347_RS06065	COG1136	(ABC) transporter
GT347_RS06095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GT347_RS06105	COG0613	PHP domain protein
GT347_RS06115	COG0009	L-threonylcarbamoyladenylate synthase
GT347_RS06120	COG1994	Peptidase M50
GT347_RS06125	COG0180	Tryptophanyl-tRNA synthetase
GT347_RS06170	COG1620	l-lactate permease
GT347_RS06175	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS06185	COG0583	DNA-binding transcription factor activity
GT347_RS06210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS06240	COG0564	pseudouridine synthase activity
GT347_RS06295	COG0514	ATP-dependent DNA helicase (RecQ)
GT347_RS06310	COG0633	Ferredoxin
GT347_RS06325	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS06335	COG4336	lyase activity
GT347_RS06345	COG0848	biopolymer transport protein
GT347_RS06350	COG0811	peptide transport
GT347_RS06370	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS06375	COG0626	cystathionine gamma-synthase activity
GT347_RS06380	COG0300	oxidoreductase activity
GT347_RS06385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS06420	COG1253	flavin adenine dinucleotide binding
GT347_RS06430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GT347_RS06435	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GT347_RS06440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GT347_RS06445	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS06450	COG0583	DNA-binding transcription factor activity
GT347_RS06455	COG4993	Dehydrogenase
GT347_RS06465	COG3119	arylsulfatase activity
GT347_RS06475	COG5002	protein histidine kinase activity
GT347_RS06505	COG1132	(ABC) transporter
GT347_RS06515	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GT347_RS06520	COG2207	Transcriptional regulator
GT347_RS06525	COG2223	nitrite transmembrane transporter activity
GT347_RS06550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT347_RS06560	COG1595	DNA-templated transcription, initiation
GT347_RS06570	COG3706	GGDEF domain
GT347_RS06570	COG2203	Gaf domain
GT347_RS06570	COG4251	negative regulation of phosphorylation
GT347_RS06570	COG5001	Diguanylate cyclase
GT347_RS06575	COG0583	DNA-binding transcription factor activity
GT347_RS06610	COG0579	oxidoreductase
GT347_RS06620	COG1414	Transcriptional regulator
GT347_RS06645	COG1609	Transcriptional regulator
GT347_RS06655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS06680	COG0217	transcriptional regulatory protein
GT347_RS06700	COG2814	Major facilitator Superfamily
GT347_RS06710	COG1309	transcriptional regulator
GT347_RS06715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GT347_RS06725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GT347_RS06770	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS06780	COG2378	regulation of single-species biofilm formation
GT347_RS06800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_RS06810	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS06840	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS06845	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS06855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GT347_RS06865	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GT347_RS06875	COG0110	maltose O-acetyltransferase activity
GT347_RS06920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS06925	COG0601	transmembrane transport
GT347_RS06930	COG0747	negative chemotaxis
GT347_RS06935	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS06945	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GT347_RS06950	COG0583	DNA-binding transcription factor activity
GT347_RS06955	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS06960	COG0300	oxidoreductase activity
GT347_RS06975	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT347_RS06980	COG0583	DNA-binding transcription factor activity
GT347_RS07005	COG2995	paraquat-inducible protein a
GT347_RS07010	COG2995	paraquat-inducible protein a
GT347_RS07015	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT347_RS07015	COG3008	intermembrane lipid transfer
GT347_RS07035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS07040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS07060	COG3415	Transposase
GT347_RS07060	COG2801	Transposase and inactivated derivatives
GT347_RS07100	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS07105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GT347_RS07120	COG0583	DNA-binding transcription factor activity
GT347_RS07130	COG2814	Major facilitator Superfamily
GT347_RS07160	COG0583	DNA-binding transcription factor activity
GT347_RS07180	COG2186	Transcriptional regulator
GT347_RS07185	COG1312	Catalyzes the dehydration of D-mannonate
GT347_RS07200	COG0154	amidase activity
GT347_RS07210	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS07225	COG3842	ATPase activity
GT347_RS07235	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS07245	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GT347_RS07250	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS07255	COG3842	ATPase activity
GT347_RS07260	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_RS07265	COG1177	transmembrane transport
GT347_RS07275	COG1321	iron dependent repressor
GT347_RS07280	COG1609	Transcriptional regulator
GT347_RS07295	COG0601	transmembrane transport
GT347_RS07315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT347_RS07320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GT347_RS07325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GT347_RS07340	COG1561	YicC-like family, N-terminal region
GT347_RS07345	COG0194	GDP metabolic process
GT347_RS07350	COG1758	RNA polymerase activity
GT347_RS07355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GT347_RS07370	COG0406	alpha-ribazole phosphatase activity
GT347_RS07390	COG0745	RESPONSE REGULATOR receiver
GT347_RS07410	COG0494	nUDIX hydrolase
GT347_RS07415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GT347_RS07435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GT347_RS07450	COG2226	methyltransferase
GT347_RS07475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS07480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT347_RS07490	COG1960	acyl-CoA dehydrogenase activity
GT347_RS07505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT347_RS07505	COG0189	ligase activity
GT347_RS07510	COG1132	(ABC) transporter
GT347_RS07520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GT347_RS07530	COG3437	response regulator, receiver
GT347_RS07550	COG1459	type II secretion system
GT347_RS07555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_RS07560	COG0720	synthase
GT347_RS07565	COG0602	queuosine metabolic process
GT347_RS07570	COG3842	ATPase activity
GT347_RS07580	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_RS07585	COG1177	transmembrane transport
GT347_RS07605	COG0792	nuclease activity
GT347_RS07615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_RS07620	COG0577	efflux transmembrane transporter activity
GT347_RS07620	COG1136	(ABC) transporter
GT347_RS07640	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GT347_RS07645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GT347_RS07655	COG0642	Histidine kinase
GT347_RS07660	COG0745	RESPONSE REGULATOR receiver
GT347_RS07680	COG3045	CreA protein
GT347_RS07685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GT347_RS07700	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GT347_RS07725	COG0501	Belongs to the peptidase M48B family
GT347_RS07735	COG0418	dihydroorotase activity
GT347_RS07750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS07770	COG1126	abc transporter atp-binding protein
GT347_RS07775	COG0765	amino acid transport
GT347_RS07780	COG0765	amino acid transport
GT347_RS07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS07790	COG0583	DNA-binding transcription factor activity
GT347_RS07795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS07800	COG5265	(ABC) transporter
GT347_RS07805	COG1607	acyl-coa hydrolase
GT347_RS07810	COG1024	Enoyl-CoA hydratase
GT347_RS07820	COG1309	transcriptional regulator
GT347_RS07825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GT347_RS07830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT347_RS07865	COG1216	Glycosyl transferase, family 2
GT347_RS07865	COG0438	transferase activity, transferring glycosyl groups
GT347_RS07880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GT347_RS07895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GT347_RS07930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT347_RS07935	COG2201	protein-glutamate methylesterase activity
GT347_RS07940	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GT347_RS07945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT347_RS07950	COG0835	chemotaxis
GT347_RS07955	COG2198	Histidine kinase
GT347_RS07955	COG0643	Histidine kinase
GT347_RS07960	COG2205	protein histidine kinase activity
GT347_RS07960	COG0784	Response regulator, receiver
GT347_RS07975	COG2197	response regulator
GT347_RS07980	COG1684	flagellar biosynthetic protein fliR
GT347_RS07985	COG1987	bacterial-type flagellum assembly
GT347_RS08000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT347_RS08035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT347_RS08040	COG1766	The M ring may be actively involved in energy transduction
GT347_RS08060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GT347_RS08065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GT347_RS08080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT347_RS08150	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GT347_RS08160	COG0745	RESPONSE REGULATOR receiver
GT347_RS08165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GT347_RS08180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_RS08190	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_RS08205	COG1191	sigma factor activity
GT347_RS08225	COG1815	bacterial-type flagellum-dependent cell motility
GT347_RS08230	COG1558	bacterial-type flagellum-dependent cell motility
GT347_RS08240	COG1749	Flagellar hook protein flgE
GT347_RS08245	COG4787	bacterial-type flagellum-dependent cell motility
GT347_RS08250	COG4786	Flagellar basal body rod
GT347_RS08255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT347_RS08260	COG1706	bacterial-type flagellum-dependent cell motility
GT347_RS08265	COG1705	Flagellar rod assembly protein muramidase FlgJ
GT347_RS08265	COG3951	Flagellar rod assembly protein muramidase FlgJ
GT347_RS08270	COG1256	bacterial-type flagellum assembly
GT347_RS08290	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS08295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GT347_RS08305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_RS08310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS08335	COG1335	isochorismatase
GT347_RS08350	COG1322	Protein conserved in bacteria
GT347_RS08360	COG0123	including yeast histone deacetylase and acetoin utilization protein
GT347_RS08430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT347_RS08450	COG0285	dihydrofolate synthase activity
GT347_RS08455	COG1393	Belongs to the ArsC family
GT347_RS08470	COG1595	DNA-templated transcription, initiation
GT347_RS08475	COG3123	guanosine phosphorylase activity
GT347_RS08480	COG0137	argininosuccinate synthase activity
GT347_RS08495	COG1472	Belongs to the glycosyl hydrolase 3 family
GT347_RS08500	COG0736	holo-[acyl-carrier-protein] synthase activity
GT347_RS08505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GT347_RS08510	COG1381	Involved in DNA repair and RecF pathway recombination
GT347_RS08515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GT347_RS08520	COG0571	ribonuclease III activity
GT347_RS08530	COG0681	Belongs to the peptidase S26 family
GT347_RS08535	COG0481	GTPase activity
GT347_RS08540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT347_RS08565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GT347_RS08570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT347_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS08580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GT347_RS08585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GT347_RS08590	COG0416	fatty acid biosynthetic process
GT347_RS08595	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GT347_RS08600	COG1399	metal-binding, possibly nucleic acid-binding protein
GT347_RS08605	COG0424	maF-like protein
GT347_RS08615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GT347_RS08615	COG0616	signal peptide processing
GT347_RS08625	COG0546	phosphoglycolate phosphatase activity
GT347_RS08635	COG1530	ribonuclease E activity
GT347_RS08640	COG3022	response to hydroperoxide
GT347_RS08650	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT347_RS08650	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GT347_RS08665	COG0784	Response regulator, receiver
GT347_RS08675	COG1914	H( )-stimulated, divalent metal cation uptake system
GT347_RS08685	COG0778	Nitroreductase
GT347_RS08690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT347_RS08700	COG5001	Diguanylate cyclase
GT347_RS08700	COG3300	MHYT domain
GT347_RS08720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GT347_RS08725	COG2916	Histone family protein nucleoid-structuring protein H-NS
GT347_RS08730	COG1253	flavin adenine dinucleotide binding
GT347_RS08735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GT347_RS08740	COG0513	Belongs to the DEAD box helicase family
GT347_RS08745	COG2321	neutral zinc metallopeptidase
GT347_RS08750	COG3706	GGDEF domain
GT347_RS08750	COG0745	RESPONSE REGULATOR receiver
GT347_RS08765	COG0402	S-adenosylhomocysteine deaminase activity
GT347_RS08775	COG0583	DNA-binding transcription factor activity
GT347_RS08780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GT347_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS08790	COG0697	spore germination
GT347_RS08810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GT347_RS08815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GT347_RS08820	COG0084	hydrolase, TatD family'
GT347_RS08825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT347_RS08830	COG0714	Associated with various cellular activities
GT347_RS08840	COG2304	oxidoreductase activity
GT347_RS08845	COG5001	Diguanylate cyclase
GT347_RS08845	COG4251	negative regulation of phosphorylation
GT347_RS08845	COG3706	GGDEF domain
GT347_RS08845	COG2203	Gaf domain
GT347_RS08860	COG4191	Histidine kinase
GT347_RS08860	COG0784	Response regulator, receiver
GT347_RS08875	COG0456	acetyltransferase
GT347_RS08925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS08930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS08940	COG3618	amidohydrolase
GT347_RS08965	COG0400	carboxylic ester hydrolase activity
GT347_RS08970	COG3384	dioxygenase
GT347_RS08985	COG2814	Major facilitator Superfamily
GT347_RS09035	COG2186	Transcriptional regulator
GT347_RS09055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GT347_RS09060	COG1253	flavin adenine dinucleotide binding
GT347_RS09075	COG0442	prolyl-tRNA aminoacylation
GT347_RS09080	COG0494	nUDIX hydrolase
GT347_RS09090	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GT347_RS09095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GT347_RS09100	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GT347_RS09105	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GT347_RS09110	COG0142	geranyltranstransferase activity
GT347_RS09125	COG0596	Alpha beta hydrolase
GT347_RS09130	COG2205	protein histidine kinase activity
GT347_RS09135	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GT347_RS09175	COG0673	inositol 2-dehydrogenase activity
GT347_RS09180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GT347_RS09185	COG0237	dephospho-CoA kinase activity
GT347_RS09195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GT347_RS09200	COG0494	nUDIX hydrolase
GT347_RS09210	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GT347_RS09215	COG0653	protein targeting
GT347_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS09270	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS09290	COG3246	L-lysine catabolic process to acetate
GT347_RS09295	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GT347_RS09300	COG0656	L-ascorbic acid biosynthetic process
GT347_RS09310	COG0583	DNA-binding transcription factor activity
GT347_RS09330	COG2969	positive regulation of protein catabolic process
GT347_RS09335	COG0625	glutathione transferase activity
GT347_RS09340	COG2857	Cytochrome c1
GT347_RS09345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GT347_RS09350	COG0723	plastoquinol--plastocyanin reductase activity
GT347_RS09355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GT347_RS09360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GT347_RS09375	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS09390	COG0410	ABC transporter
GT347_RS09395	COG0805	protein transport
GT347_RS09400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT347_RS09405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GT347_RS09410	COG0537	adenosine 5'-monophosphoramidase activity
GT347_RS09420	COG0140	phosphoribosyl-ATP diphosphatase activity
GT347_RS09425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GT347_RS09430	COG0107	imidazoleglycerol-phosphate synthase activity
GT347_RS09440	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GT347_RS09450	COG0131	Imidazoleglycerol-phosphate dehydratase
GT347_RS09455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GT347_RS09465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GT347_RS09470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GT347_RS09475	COG0271	Belongs to the BolA IbaG family
GT347_RS09480	COG0842	Transport permease protein
GT347_RS09485	COG1131	(ABC) transporter
GT347_RS09495	COG2854	intermembrane phospholipid transfer
GT347_RS09505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GT347_RS09510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GT347_RS09515	COG1127	ABC transporter
GT347_RS09525	COG0069	glutamate synthase activity
GT347_RS09525	COG0070	glutamate synthase
GT347_RS09525	COG0067	glutamate synthase
GT347_RS09560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GT347_RS09565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GT347_RS09610	COG1965	Belongs to the frataxin family
GT347_RS09630	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GT347_RS09640	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GT347_RS09650	COG1333	cytochrome c biogenesis protein
GT347_RS09660	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GT347_RS09680	COG1560	Kdo2-lipid A biosynthetic process
GT347_RS09685	COG1560	Kdo2-lipid A biosynthetic process
GT347_RS09690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GT347_RS09700	COG1538	Outer membrane efflux protein
GT347_RS09720	COG2814	Major facilitator Superfamily
GT347_RS09725	COG0583	DNA-binding transcription factor activity
GT347_RS09740	COG1742	UPF0060 membrane protein
GT347_RS09745	COG0840	transmembrane signaling receptor activity
GT347_RS09750	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GT347_RS09765	COG5001	Diguanylate cyclase
GT347_RS09765	COG4251	negative regulation of phosphorylation
GT347_RS09765	COG3706	GGDEF domain
GT347_RS09765	COG2203	Gaf domain
GT347_RS09770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GT347_RS09775	COG0459	protein refolding
GT347_RS09780	COG0166	Belongs to the GPI family
GT347_RS09785	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GT347_RS09790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GT347_RS09850	COG0540	Belongs to the ATCase OTCase family
GT347_RS09855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GT347_RS09860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GT347_RS09865	COG1678	Uncharacterized ACR, COG1678
GT347_RS09870	COG0415	Belongs to the DNA photolyase family
GT347_RS09905	COG1773	rubredoxin
GT347_RS09915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GT347_RS09920	COG4772	TonB-dependent receptor
GT347_RS09930	COG3284	Transcriptional regulator
GT347_RS09935	COG0138	bifunctional purine biosynthesis protein purh
GT347_RS09940	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GT347_RS09950	COG1238	metal cluster binding
GT347_RS09965	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
GT347_RS09975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GT347_RS09980	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GT347_RS10095	COG0583	DNA-binding transcription factor activity
GT347_RS10130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GT347_RS10135	COG0583	DNA-binding transcription factor activity
GT347_RS10145	COG5383	Protein conserved in bacteria
GT347_RS10150	COG0583	DNA-binding transcription factor activity
GT347_RS10155	COG2186	Transcriptional regulator
GT347_RS10170	COG0747	negative chemotaxis
GT347_RS10180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS10185	COG4608	Belongs to the ABC transporter superfamily
GT347_RS10190	COG0444	Belongs to the ABC transporter superfamily
GT347_RS10200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT347_RS10210	COG1473	amidohydrolase
GT347_RS10235	COG1566	PFAM secretion protein HlyD family protein
GT347_RS10260	COG2375	cellular response to nickel ion
GT347_RS10280	COG0671	phosphoesterase, PA-phosphatase related
GT347_RS10295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS10310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS10320	COG0688	phosphatidylethanolamine metabolic process
GT347_RS10335	COG0583	DNA-binding transcription factor activity
GT347_RS10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS10370	COG0384	phenazine biosynthesis protein PhzF
GT347_RS10375	COG0625	glutathione transferase activity
GT347_RS10380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS10390	COG4774	siderophore transport
GT347_RS10400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS10405	COG0601	transmembrane transport
GT347_RS10410	COG0747	negative chemotaxis
GT347_RS10415	COG4172	Belongs to the ABC transporter superfamily
GT347_RS10425	COG1414	Transcriptional regulator
GT347_RS10430	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS10445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT347_RS10460	COG0765	amino acid transport
GT347_RS10465	COG0765	amino acid transport
GT347_RS10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS10480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS10485	COG0277	FAD linked oxidase domain protein
GT347_RS10495	COG0010	Belongs to the arginase family
GT347_RS10500	COG2814	Major facilitator Superfamily
GT347_RS10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_RS10525	COG2084	Dehydrogenase
GT347_RS10535	COG0210	DNA helicase
GT347_RS10550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GT347_RS10590	COG2337	Toxic component of a toxin-antitoxin (TA) module
GT347_RS10595	COG0037	tRNA processing
GT347_RS10615	COG2255	four-way junction helicase activity
GT347_RS10635	COG0632	four-way junction helicase activity
GT347_RS10640	COG1702	phosphate starvation-inducible protein PhoH
GT347_RS10645	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GT347_RS10650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GT347_RS10655	COG1490	D-aminoacyl-tRNA deacylase activity
GT347_RS10665	COG0583	DNA-binding transcription factor activity
GT347_RS10680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT347_RS10695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GT347_RS10700	COG1131	(ABC) transporter
GT347_RS10705	COG0842	Transport permease protein
GT347_RS10710	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_RS10720	COG0277	FAD linked oxidase domain protein
GT347_RS10725	COG2271	Major facilitator Superfamily
GT347_RS10730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT347_RS10735	COG4628	conserved protein (DUF2132)
GT347_RS10740	COG0326	Molecular chaperone. Has ATPase activity
GT347_RS10745	COG1187	pseudouridine synthase activity
GT347_RS10760	COG0165	Argininosuccinate lyase
GT347_RS10775	COG1914	H( )-stimulated, divalent metal cation uptake system
GT347_RS10780	COG0405	Gamma-glutamyltransferase
GT347_RS10805	COG0509	glycine decarboxylation via glycine cleavage system
GT347_RS10810	COG0235	Class ii aldolase
GT347_RS10820	COG0384	phenazine biosynthesis protein PhzF
GT347_RS10835	COG0012	GTP binding
GT347_RS10840	COG0297	glycogen (starch) synthase activity
GT347_RS10840	COG0438	transferase activity, transferring glycosyl groups
GT347_RS10845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS10855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GT347_RS10860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT347_RS10915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS10930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS10935	COG1686	Belongs to the peptidase S11 family
GT347_RS10945	COG0473	3-isopropylmalate dehydrogenase activity
GT347_RS10980	COG2159	amidohydrolase
GT347_RS10990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GT347_RS11005	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS11010	COG3384	dioxygenase
GT347_RS11015	COG0583	DNA-binding transcription factor activity
GT347_RS11060	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_RS11065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_RS11075	COG0583	DNA-binding transcription factor activity
GT347_RS11080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_RS11085	COG0583	DNA-binding transcription factor activity
GT347_RS11100	COG0583	DNA-binding transcription factor activity
GT347_RS11130	COG2814	Major facilitator Superfamily
GT347_RS11140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS11155	COG4172	Belongs to the ABC transporter superfamily
GT347_RS11185	COG0583	DNA-binding transcription factor activity
GT347_RS11190	COG1414	Transcriptional regulator
GT347_RS11200	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS11210	COG0667	Aldo Keto reductase
GT347_RS11240	COG1177	transmembrane transport
GT347_RS11245	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_RS11270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_RS11275	COG2072	flavoprotein involved in K transport
GT347_RS11280	COG3842	ATPase activity
GT347_RS11295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT347_RS11300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS11305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT347_RS11325	COG0411	ABC transporter
GT347_RS11360	COG0583	DNA-binding transcription factor activity
GT347_RS11385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS11400	COG0765	amino acid transport
GT347_RS11420	COG0583	DNA-binding transcription factor activity
GT347_RS11445	COG0583	DNA-binding transcription factor activity
GT347_RS11460	COG0437	4 iron, 4 sulfur cluster binding
GT347_RS11465	COG2864	formate dehydrogenase
GT347_RS11495	COG1609	Transcriptional regulator
GT347_RS11515	COG2801	Transposase and inactivated derivatives
GT347_RS11515	COG3415	Transposase
GT347_RS11520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_RS11525	COG1335	isochorismatase
GT347_RS11530	COG0251	oxidation-reduction process
GT347_RS11535	COG2267	carboxylic ester hydrolase activity
GT347_RS11540	COG0778	Nitroreductase
GT347_RS11545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_RS11550	COG3971	2-oxopent-4-enoate hydratase activity
GT347_RS11555	COG0179	Fumarylacetoacetate (FAA) hydrolase
GT347_RS11565	COG0251	oxidation-reduction process
GT347_RS11575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_RS11580	COG1414	Transcriptional regulator
GT347_RS11620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GT347_RS11630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GT347_RS11635	COG0736	holo-[acyl-carrier-protein] synthase activity
GT347_RS11640	COG1802	Transcriptional regulator
GT347_RS11645	COG2423	ornithine cyclodeaminase activity
GT347_RS11670	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS11685	COG3069	C4-dicarboxylate transmembrane transporter activity
GT347_RS11695	COG0154	amidase activity
GT347_RS11725	COG2814	Major facilitator Superfamily
GT347_RS11735	COG1609	Transcriptional regulator
GT347_RS11745	COG1846	Transcriptional regulator
GT347_RS11750	COG1764	response to oxidative stress
GT347_RS11760	COG0025	NhaP-type Na H and K H
GT347_RS11780	COG0642	Histidine kinase
GT347_RS11790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS11810	COG2204	response regulator
GT347_RS11815	COG5000	phosphorelay sensor kinase activity
GT347_RS11835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GT347_RS11840	COG0085	RNA polymerase activity
GT347_RS11845	COG0222	ribosome binding
GT347_RS11850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GT347_RS11855	COG0081	regulation of translation
GT347_RS11860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GT347_RS11880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT347_RS11905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GT347_RS11910	COG0134	indole-3-glycerol-phosphate synthase activity
GT347_RS11915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT347_RS11930	COG0546	phosphoglycolate phosphatase activity
GT347_RS11950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GT347_RS11955	COG2967	ApaG domain
GT347_RS11965	COG2199	diguanylate cyclase activity
GT347_RS11980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GT347_RS11985	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS12005	COG4335	DNA alkylation repair
GT347_RS12015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GT347_RS12030	COG0653	protein targeting
GT347_RS12035	COG0069	glutamate synthase activity
GT347_RS12050	COG1802	Transcriptional regulator
GT347_RS12065	COG3395	kinase activity
GT347_RS12070	COG0235	Class ii aldolase
GT347_RS12085	COG2814	Major facilitator Superfamily
GT347_RS12095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GT347_RS12120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GT347_RS12125	COG1137	ATPase activity
GT347_RS12130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GT347_RS12135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GT347_RS12145	COG0018	arginyl-trna synthetase
GT347_RS12160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GT347_RS12170	COG1942	4-Oxalocrotonate Tautomerase
GT347_RS12175	COG0121	glutamine amidotransferase
GT347_RS12205	COG0189	ligase activity
GT347_RS12210	COG3135	benzoate transporter
GT347_RS12215	COG3158	transport of potassium into the cell
GT347_RS12225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GT347_RS12240	COG0495	leucyl-tRNA aminoacylation
GT347_RS12255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GT347_RS12260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT347_RS12265	COG0735	belongs to the Fur family
GT347_RS12270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GT347_RS12280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GT347_RS12285	COG0598	Magnesium transport protein CorA
GT347_RS12290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GT347_RS12295	COG0318	PFAM AMP-dependent synthetase and ligase
GT347_RS12310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GT347_RS12315	COG1862	Preprotein translocase
GT347_RS12350	COG0583	DNA-binding transcription factor activity
GT347_RS12365	COG0583	DNA-binding transcription factor activity
GT347_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS12375	COG1794	racemase activity, acting on amino acids and derivatives
GT347_RS12385	COG2885	chlorophyll binding
GT347_RS12405	COG3188	usher protein
GT347_RS12425	COG0469	pyruvate kinase activity
GT347_RS12430	COG0405	Gamma-glutamyltransferase
GT347_RS12435	COG0126	phosphoglycerate kinase activity
GT347_RS12455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT347_RS12465	COG0242	peptide deformylase activity
GT347_RS12475	COG0758	DNA mediated transformation
GT347_RS12485	COG0629	single-stranded DNA binding
GT347_RS12490	COG0513	Belongs to the DEAD box helicase family
GT347_RS12510	COG5001	Diguanylate cyclase
GT347_RS12525	COG0482	sulfurtransferase activity
GT347_RS12530	COG0583	DNA-binding transcription factor activity
GT347_RS12535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS12540	COG3799	methylaspartate ammonia-lyase activity
GT347_RS12550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS12570	COG0840	transmembrane signaling receptor activity
GT347_RS12590	COG0235	Class ii aldolase
GT347_RS12595	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS12610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS12615	COG2814	Major facilitator Superfamily
GT347_RS12620	COG3706	GGDEF domain
GT347_RS12635	COG2814	Major facilitator Superfamily
GT347_RS12655	COG2186	Transcriptional regulator
GT347_RS12665	COG2423	ornithine cyclodeaminase activity
GT347_RS12680	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
GT347_RS12700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_RS12710	COG4566	intracellular signal transduction
GT347_RS12720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GT347_RS12735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GT347_RS12740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GT347_RS12765	COG3550	peptidyl-serine autophosphorylation
GT347_RS12775	COG0646	methionine synthase
GT347_RS12775	COG1410	methionine synthase
GT347_RS12785	COG3550	peptidyl-serine autophosphorylation
GT347_RS12790	COG1047	Peptidyl-prolyl cis-trans
GT347_RS12795	COG0023	Translation Initiation Factor
GT347_RS12810	COG3267	Type II secretory pathway component ExeA
GT347_RS12810	COG3409	Peptidoglycan-binding domain 1 protein
GT347_RS12830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GT347_RS12835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GT347_RS12855	COG0006	proline dipeptidase activity
GT347_RS12870	COG2814	Major facilitator Superfamily
GT347_RS12875	COG0737	Belongs to the 5'-nucleotidase family
GT347_RS12895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GT347_RS12900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_RS12905	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GT347_RS12915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GT347_RS12935	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT347_RS12940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GT347_RS12950	COG0300	oxidoreductase activity
GT347_RS12980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GT347_RS12985	COG0706	membrane insertase activity
GT347_RS12990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GT347_RS12995	COG0594	ribonuclease P activity
GT347_RS13000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GT347_RS13005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GT347_RS13055	COG1064	alcohol dehydrogenase
GT347_RS13065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GT347_RS13075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GT347_RS13080	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS13090	COG2608	mercury ion transmembrane transporter activity
GT347_RS13095	COG2974	May be involved in recombination
GT347_RS13115	COG3568	Endonuclease Exonuclease Phosphatase
GT347_RS13120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT347_RS13125	COG0392	lysyltransferase activity
GT347_RS13135	COG1573	uracil-dna glycosylase
GT347_RS13150	COG0583	DNA-binding transcription factor activity
GT347_RS13155	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS13160	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS13165	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS13170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GT347_RS13175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS13180	COG0583	DNA-binding transcription factor activity
GT347_RS13185	COG1396	sequence-specific DNA binding
GT347_RS13195	COG1408	metallophosphoesterase
GT347_RS13200	COG2814	Major facilitator Superfamily
GT347_RS13220	COG2217	Heavy metal translocating P-type atpase
GT347_RS13225	COG0840	transmembrane signaling receptor activity
GT347_RS13235	COG0583	DNA-binding transcription factor activity
GT347_RS13240	COG0277	FAD linked oxidase domain protein
GT347_RS13260	COG3300	MHYT domain
GT347_RS13260	COG5001	Diguanylate cyclase
GT347_RS13280	COG1475	DNA binding
GT347_RS13290	COG1192	Involved in chromosome partitioning
GT347_RS13295	COG0357	Ribosomal RNA small subunit methyltransferase G
GT347_RS13330	COG0625	glutathione transferase activity
GT347_RS13335	COG4178	(ABC) transporter
GT347_RS13340	COG1902	pentaerythritol trinitrate reductase activity
GT347_RS13395	COG0625	glutathione transferase activity
GT347_RS13400	COG1609	Transcriptional regulator
GT347_RS13405	COG1609	Transcriptional regulator
GT347_RS13410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_RS13415	COG1022	Amp-dependent synthetase and ligase
GT347_RS13420	COG0411	ABC transporter
GT347_RS13425	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS13455	COG3706	GGDEF domain
GT347_RS13460	COG0850	regulation of cytokinetic process
GT347_RS13470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GT347_RS13485	COG0284	orotidine-5'-phosphate decarboxylase activity
GT347_RS13505	COG2027	D-alanyl-D-alanine carboxypeptidase
GT347_RS13515	COG0009	L-threonylcarbamoyladenylate synthase
GT347_RS13520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GT347_RS13525	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GT347_RS13530	COG3118	belongs to the thioredoxin family
GT347_RS13535	COG1902	pentaerythritol trinitrate reductase activity
GT347_RS13565	COG0457	Tetratricopeptide repeat
GT347_RS13570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GT347_RS13575	COG0457	Tetratricopeptide repeat
GT347_RS13580	COG1215	transferase activity, transferring glycosyl groups
GT347_RS13585	COG1215	transferase activity, transferring glycosyl groups
GT347_RS13590	COG1192	Involved in chromosome partitioning
GT347_RS13605	COG2814	Major facilitator Superfamily
GT347_RS13635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GT347_RS13640	COG2801	Transposase and inactivated derivatives
GT347_RS13640	COG3415	Transposase
GT347_RS13660	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GT347_RS13660	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GT347_RS13680	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS13690	COG0642	Histidine kinase
GT347_RS13705	COG2203	Gaf domain
GT347_RS13705	COG3706	GGDEF domain
GT347_RS13705	COG5001	Diguanylate cyclase
GT347_RS13705	COG4251	negative regulation of phosphorylation
GT347_RS13715	COG0154	amidase activity
GT347_RS13725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GT347_RS13735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GT347_RS13740	COG2137	regulation of response to DNA damage stimulus
GT347_RS13750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS13755	COG4166	transmembrane transport
GT347_RS13760	COG4172	Belongs to the ABC transporter superfamily
GT347_RS13795	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_RS13795	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GT347_RS13805	COG1764	response to oxidative stress
GT347_RS13820	COG1522	sequence-specific DNA binding
GT347_RS13840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GT347_RS13875	COG2094	Belongs to the DNA glycosylase MPG family
GT347_RS13880	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS13900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GT347_RS13905	COG0045	succinate-CoA ligase (ADP-forming) activity
GT347_RS13910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GT347_RS13915	COG0861	Integral membrane protein TerC family
GT347_RS13920	COG0631	protein serine/threonine phosphatase activity
GT347_RS13925	COG1716	ATPase activity
GT347_RS13940	COG4969	Belongs to the N-Me-Phe pilin family
GT347_RS13965	COG4783	chaperone-mediated protein folding
GT347_RS13970	COG1950	PFAM Membrane protein of
GT347_RS13980	COG0861	Integral membrane protein TerC family
GT347_RS13990	COG4681	YaeQ
GT347_RS14000	COG0625	glutathione transferase activity
GT347_RS14005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GT347_RS14060	COG0583	DNA-binding transcription factor activity
GT347_RS14075	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS14080	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_RS14095	COG0347	Belongs to the P(II) protein family
GT347_RS14100	COG0004	ammonium transporteR
GT347_RS14110	COG0277	FAD linked oxidase domain protein
GT347_RS14120	COG0247	lactate metabolic process
GT347_RS14135	COG0477	Major facilitator Superfamily
GT347_RS14145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT347_RS14155	COG0700	Nucleoside recognition
GT347_RS14230	COG0745	RESPONSE REGULATOR receiver
GT347_RS14270	COG0708	Exodeoxyribonuclease III
GT347_RS14275	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GT347_RS14300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GT347_RS14305	COG0154	amidase activity
GT347_RS14310	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GT347_RS14315	COG1077	Cell shape determining protein MreB Mrl
GT347_RS14320	COG1792	Involved in formation and maintenance of cell shape
GT347_RS14330	COG0768	penicillin binding
GT347_RS14340	COG0004	ammonium transporteR
GT347_RS14350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GT347_RS14355	COG1127	ABC transporter
GT347_RS14370	COG0412	Dienelactone hydrolase
GT347_RS14375	COG0598	Magnesium transport protein CorA
GT347_RS14395	COG3411	Ferredoxin
GT347_RS14400	COG2945	thiolester hydrolase activity
GT347_RS14405	COG1686	Belongs to the peptidase S11 family
GT347_RS14410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GT347_RS14415	COG0049	tRNA binding
GT347_RS14420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GT347_RS14425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GT347_RS14430	COG0051	transcription antitermination factor activity, RNA binding
GT347_RS14435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GT347_RS14440	COG0088	Forms part of the polypeptide exit tunnel
GT347_RS14445	COG0089	rRNA binding
GT347_RS14450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GT347_RS14455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GT347_RS14460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GT347_RS14465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GT347_RS14470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GT347_RS14475	COG0255	Belongs to the universal ribosomal protein uL29 family
GT347_RS14480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GT347_RS14485	COG0678	peroxiredoxin activity
GT347_RS14485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT347_RS14510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GT347_RS14515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GT347_RS14525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GT347_RS14530	COG0321	lipoyl(octanoyl) transferase activity
GT347_RS14535	COG2921	Belongs to the UPF0250 family
GT347_RS14550	COG0356	it plays a direct role in the translocation of protons across the membrane
GT347_RS14560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GT347_RS14565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GT347_RS14570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GT347_RS14575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GT347_RS14580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GT347_RS14585	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GT347_RS14595	COG1793	dna ligase
GT347_RS14595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GT347_RS14600	COG1793	dna ligase
GT347_RS14610	COG1201	RNA secondary structure unwinding
GT347_RS14660	COG0438	transferase activity, transferring glycosyl groups
GT347_RS14665	COG3245	cytochrome
GT347_RS14670	COG1538	Outer membrane efflux protein
GT347_RS14675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT347_RS14680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_RS14695	COG0583	DNA-binding transcription factor activity
GT347_RS14740	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS14745	COG0583	DNA-binding transcription factor activity
GT347_RS14760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT347_RS14765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_RS14775	COG1538	Outer membrane efflux protein
GT347_RS14810	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT347_RS14810	COG2918	glutathione biosynthetic process
GT347_RS14925	COG1191	sigma factor activity
GT347_RS14955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GT347_RS14970	COG1157	protein secretion by the type III secretion system
GT347_RS14990	COG1677	Flagellar hook-basal body complex protein FliE
GT347_RS15000	COG1815	bacterial-type flagellum-dependent cell motility
GT347_RS15005	COG1706	bacterial-type flagellum-dependent cell motility
GT347_RS15010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GT347_RS15025	COG4786	Flagellar basal body rod
GT347_RS15030	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_RS15040	COG1684	flagellar biosynthetic protein fliR
GT347_RS15045	COG1987	bacterial-type flagellum assembly
GT347_RS15130	COG0343	queuine tRNA-ribosyltransferase activity
GT347_RS15145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GT347_RS15160	COG0783	Belongs to the Dps family
GT347_RS15165	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GT347_RS15175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GT347_RS15185	COG3842	ATPase activity
GT347_RS15200	COG0395	ABC-type sugar transport system, permease component
GT347_RS15215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GT347_RS15220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GT347_RS15225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GT347_RS15230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GT347_RS15235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GT347_RS15240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GT347_RS15245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GT347_RS15250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GT347_RS15260	COG1841	ribosomal large subunit assembly
GT347_RS15265	COG0200	Binds to the 23S rRNA
GT347_RS15275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GT347_RS15280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GT347_RS15285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GT347_RS15290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GT347_RS15295	COG0202	RNA polymerase activity
GT347_RS15300	COG0203	ribosomal protein L17
GT347_RS15310	COG1802	Transcriptional regulator
GT347_RS15320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS15325	COG0251	oxidation-reduction process
GT347_RS15330	COG0235	Class ii aldolase
GT347_RS15335	COG0235	Class ii aldolase
GT347_RS15345	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS15350	COG1396	sequence-specific DNA binding
GT347_RS15365	COG0725	ABC transporter, periplasmic molybdate-binding protein
GT347_RS15370	COG4149	molybdate abc transporter
GT347_RS15375	COG1971	Probably functions as a manganese efflux pump
GT347_RS15410	COG1254	Belongs to the acylphosphatase family
GT347_RS15430	COG0420	3'-5' exonuclease activity
GT347_RS15440	COG2801	Transposase and inactivated derivatives
GT347_RS15440	COG3415	Transposase
GT347_RS15445	COG1309	transcriptional regulator
GT347_RS15465	COG1129	ABC transporter
GT347_RS15505	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS15515	COG1724	mRNA binding
GT347_RS15520	COG1598	PFAM Uncharacterised protein family UPF0150
GT347_RS15540	COG2080	2 iron, 2 sulfur cluster binding
GT347_RS15545	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT347_RS15550	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_RS15555	COG0028	Belongs to the TPP enzyme family
GT347_RS15575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS15585	COG3415	Transposase
GT347_RS15585	COG2801	Transposase and inactivated derivatives
GT347_RS15590	COG2801	Transposase and inactivated derivatives
GT347_RS15590	COG3415	Transposase
GT347_RS15595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS15605	COG0752	glycyl-tRNA synthetase alpha subunit
GT347_RS15610	COG0751	glycine-tRNA ligase activity
GT347_RS15615	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GT347_RS15650	COG0288	reversible hydration of carbon dioxide
GT347_RS15655	COG0183	Belongs to the thiolase family
GT347_RS15660	COG3210	domain, Protein
GT347_RS15670	COG1902	pentaerythritol trinitrate reductase activity
GT347_RS15675	COG3012	SEC-C Motif Domain Protein
GT347_RS15685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_RS15695	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GT347_RS15710	COG2022	thiamine diphosphate biosynthetic process
GT347_RS15715	COG0351	phosphomethylpyrimidine kinase
GT347_RS15760	COG1960	acyl-CoA dehydrogenase activity
GT347_RS15765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GT347_RS15770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GT347_RS15880	COG0477	Major facilitator Superfamily
GT347_RS15890	COG0583	DNA-binding transcription factor activity
GT347_RS15895	COG1902	pentaerythritol trinitrate reductase activity
GT347_RS15900	COG2132	Multicopper oxidase
GT347_RS15910	COG2372	response to copper ion
GT347_RS15950	COG1475	DNA binding
GT347_RS16040	COG4626	Terminase
GT347_RS16040	COG1802	Transcriptional regulator
GT347_RS16160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT347_RS16165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GT347_RS16215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GT347_RS16245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GT347_RS16250	COG0183	Belongs to the thiolase family
GT347_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS16280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GT347_RS16290	COG1040	competence protein
GT347_RS16295	COG2226	methyltransferase
GT347_RS16315	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GT347_RS16345	COG1612	heme a metabolic process
GT347_RS16350	COG0109	protoheme IX farnesyltransferase activity
GT347_RS16355	COG1999	signal sequence binding
GT347_RS16365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT347_RS16375	COG0612	Peptidase, M16
GT347_RS16390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GT347_RS16435	COG2197	response regulator
GT347_RS16450	COG2982	Protein involved in outer membrane biogenesis
GT347_RS16460	COG0793	Belongs to the peptidase S41A family
GT347_RS16465	COG0588	phosphoglycerate mutase activity
GT347_RS16470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GT347_RS16475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GT347_RS16480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GT347_RS16485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GT347_RS16490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GT347_RS16495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GT347_RS16505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GT347_RS16510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GT347_RS16520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GT347_RS16530	COG1194	a g-specific adenine glycosylase
GT347_RS16535	COG1660	Displays ATPase and GTPase activities
GT347_RS16540	COG0497	DNA recombination
GT347_RS16545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GT347_RS16550	COG1420	regulation of RNA biosynthetic process
GT347_RS16565	COG1024	Enoyl-CoA hydratase
GT347_RS16575	COG1024	Enoyl-CoA hydratase
GT347_RS16580	COG1960	acyl-CoA dehydrogenase activity
GT347_RS16585	COG3180	Ammonia monooxygenase
GT347_RS16610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS16630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS16635	COG0765	amino acid transport
GT347_RS16640	COG1126	abc transporter atp-binding protein
GT347_RS16645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_RS16655	COG0006	proline dipeptidase activity
GT347_RS16670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS16680	COG4172	Belongs to the ABC transporter superfamily
GT347_RS16685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS16690	COG0601	transmembrane transport
GT347_RS16695	COG0747	negative chemotaxis
GT347_RS16705	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_RS16710	COG3842	ATPase activity
GT347_RS16720	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_RS16725	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GT347_RS16730	COG1984	allophanate hydrolase subunit 2
GT347_RS16735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GT347_RS16770	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS16790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS16795	COG1802	Transcriptional regulator
GT347_RS16820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_RS16820	COG2010	Cytochrome c
GT347_RS16825	COG2080	2 iron, 2 sulfur cluster binding
GT347_RS16830	COG1335	isochorismatase
GT347_RS16875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT347_RS16885	COG1126	abc transporter atp-binding protein
GT347_RS16900	COG0765	amino acid transport
GT347_RS16920	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GT347_RS16930	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS16940	COG0697	spore germination
GT347_RS16950	COG0243	molybdopterin cofactor binding
GT347_RS16955	COG2916	Histone family protein nucleoid-structuring protein H-NS
GT347_RS16980	COG2205	protein histidine kinase activity
GT347_RS16985	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GT347_RS17000	COG0588	phosphoglycerate mutase activity
GT347_RS17005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GT347_RS17010	COG2084	Dehydrogenase
GT347_RS17055	COG1802	Transcriptional regulator
GT347_RS17060	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS17095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS17110	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GT347_RS17115	COG3387	PFAM Glycoside hydrolase 15-related
GT347_RS17125	COG1877	trehalose-phosphatase activity
GT347_RS17135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_RS17145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT347_RS17150	COG1538	Outer membrane efflux protein
GT347_RS17155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GT347_RS17155	COG5297	Belongs to the glycosyl hydrolase family 6
GT347_RS17170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GT347_RS17195	COG0617	tRNA 3'-terminal CCA addition
GT347_RS17200	COG3279	Response regulator of the LytR AlgR family
GT347_RS17205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GT347_RS17210	COG1196	nuclear chromosome segregation
GT347_RS17210	COG0741	lytic transglycosylase activity
GT347_RS17210	COG0739	heme binding
GT347_RS17235	COG4535	Mg2 and Co2 transporter CorC
GT347_RS17240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GT347_RS17255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GT347_RS17270	COG0829	nickel cation binding
GT347_RS17280	COG0831	urea catabolic process
GT347_RS17290	COG0832	Belongs to the urease beta subunit family
GT347_RS17295	COG0804	urea catabolic process
GT347_RS17310	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GT347_RS17315	COG0830	nickel cation binding
GT347_RS17320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GT347_RS17340	COG2076	Multidrug Resistance protein
GT347_RS17375	COG0745	RESPONSE REGULATOR receiver
GT347_RS17380	COG2205	protein histidine kinase activity
GT347_RS17400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GT347_RS17435	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GT347_RS17440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GT347_RS17445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GT347_RS17470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GT347_RS17475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GT347_RS17480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GT347_RS17485	COG0316	Belongs to the HesB IscA family
GT347_RS17490	COG0477	Major facilitator Superfamily
GT347_RS17495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GT347_RS17500	COG0739	heme binding
GT347_RS17510	COG0583	DNA-binding transcription factor activity
GT347_RS17540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GT347_RS17545	COG4251	negative regulation of phosphorylation
GT347_RS17555	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GT347_RS17610	COG4770	biotin carboxylase activity
GT347_RS17615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GT347_RS17635	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GT347_RS17640	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GT347_RS17675	COG0765	amino acid transport
GT347_RS17685	COG4774	siderophore transport
GT347_RS17695	COG2188	Transcriptional regulator
GT347_RS17705	COG0066	3-isopropylmalate dehydratase activity
GT347_RS17710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_RS17730	COG4608	Belongs to the ABC transporter superfamily
GT347_RS17735	COG0444	Belongs to the ABC transporter superfamily
GT347_RS17740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS17745	COG0601	transmembrane transport
GT347_RS17750	COG0747	negative chemotaxis
GT347_RS17770	COG0778	Nitroreductase
GT347_RS17780	COG2197	response regulator
GT347_RS17785	COG4585	Histidine kinase
GT347_RS17805	COG3550	peptidyl-serine autophosphorylation
GT347_RS17815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS17825	COG1414	Transcriptional regulator
GT347_RS17830	COG0583	DNA-binding transcription factor activity
GT347_RS17840	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS17855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GT347_RS17870	COG0405	Gamma-glutamyltransferase
GT347_RS17880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS17920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GT347_RS17925	COG2146	nitrite reductase [NAD(P)H] activity
GT347_RS17930	COG0446	pyridine nucleotide-disulphide oxidoreductase
GT347_RS17955	COG3473	Maleate cis-trans isomerase
GT347_RS17960	COG0596	Alpha beta hydrolase
GT347_RS17965	COG2309	aminopeptidase activity
GT347_RS17970	COG1335	isochorismatase
GT347_RS17995	COG5001	Diguanylate cyclase
GT347_RS17995	COG5002	protein histidine kinase activity
GT347_RS18000	COG0583	DNA-binding transcription factor activity
GT347_RS18015	COG0583	DNA-binding transcription factor activity
GT347_RS18020	COG4336	lyase activity
GT347_RS18030	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS18055	COG0583	DNA-binding transcription factor activity
GT347_RS18060	COG0405	Gamma-glutamyltransferase
GT347_RS18065	COG4178	(ABC) transporter
GT347_RS18085	COG3842	ATPase activity
GT347_RS18090	COG1609	Transcriptional regulator
GT347_RS18095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GT347_RS18145	COG2847	Copper chaperone PCu(A)C
GT347_RS18160	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GT347_RS18170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GT347_RS18180	COG0523	cobalamin synthesis protein
GT347_RS18185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GT347_RS18195	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GT347_RS18200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GT347_RS18205	COG2001	Belongs to the MraZ family
GT347_RS18210	COG0275	rRNA processing
GT347_RS18225	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GT347_RS18230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GT347_RS18235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GT347_RS18240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GT347_RS18245	COG0772	Belongs to the SEDS family
GT347_RS18255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT347_RS18260	COG1181	Belongs to the D-alanine--D-alanine ligase family
GT347_RS18265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GT347_RS18275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GT347_RS18290	COG3177	Filamentation induced by cAMP protein fic
GT347_RS18310	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GT347_RS18355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_RS18425	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS18450	COG2814	Major facilitator Superfamily
GT347_RS18455	COG1639	'signal transduction protein
GT347_RS18465	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GT347_RS18510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GT347_RS18520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT347_RS18525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GT347_RS18540	COG3150	esterase
GT347_RS18555	COG0772	Belongs to the SEDS family
GT347_RS18565	COG0312	modulator of DNA gyrase
GT347_RS18585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GT347_RS18590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GT347_RS18600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GT347_RS18605	COG0511	ligase activity, forming carbon-carbon bonds
GT347_RS18610	COG0439	Biotin carboxylase
GT347_RS18615	COG2264	protein methyltransferase activity
GT347_RS18635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT347_RS18640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT347_RS18640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GT347_RS18670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GT347_RS18675	COG2943	transferase activity, transferring hexosyl groups
GT347_RS18680	COG2204	response regulator
GT347_RS18695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GT347_RS18730	COG2197	response regulator
GT347_RS18735	COG1116	anion transmembrane transporter activity
GT347_RS18735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_RS18740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS18745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_RS18745	COG1116	anion transmembrane transporter activity
GT347_RS18750	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
GT347_RS18795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS18835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS18870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS18875	COG0154	amidase activity
GT347_RS18885	COG3657	addiction module killer protein
GT347_RS18905	COG0281	malic enzyme
GT347_RS18905	COG0280	phosphate acetyltransferase
GT347_RS18920	COG3206	protein involved in exopolysaccharide biosynthesis
GT347_RS18920	COG0489	protein tyrosine kinase activity
GT347_RS18960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT347_RS18965	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GT347_RS18980	COG2346	COG2346, Truncated hemoglobins
GT347_RS18985	COG1193	negative regulation of DNA recombination
GT347_RS18990	COG2003	Belongs to the UPF0758 family
GT347_RS18995	COG1047	Peptidyl-prolyl cis-trans
GT347_RS19010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GT347_RS19030	COG1063	alcohol dehydrogenase
GT347_RS19035	COG1295	ribonuclease BN
GT347_RS19045	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_RS19050	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GT347_RS19055	COG0066	3-isopropylmalate dehydratase activity
GT347_RS19060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_RS19065	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS19120	COG2186	Transcriptional regulator
GT347_RS19125	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS19130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS19140	COG1366	Belongs to the anti-sigma-factor antagonist family
GT347_RS19145	COG1366	Belongs to the anti-sigma-factor antagonist family
GT347_RS19150	COG2172	sigma factor antagonist activity
GT347_RS19160	COG2205	protein histidine kinase activity
GT347_RS19175	COG0784	Response regulator, receiver
GT347_RS19180	COG4251	negative regulation of phosphorylation
GT347_RS19185	COG1064	alcohol dehydrogenase
GT347_RS19195	COG0791	NLP P60 protein
GT347_RS19215	COG1611	Belongs to the LOG family
GT347_RS19250	COG2059	Chromate
GT347_RS19255	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
GT347_RS19270	COG4251	negative regulation of phosphorylation
GT347_RS19270	COG3706	GGDEF domain
GT347_RS19270	COG5001	Diguanylate cyclase
GT347_RS19270	COG2203	Gaf domain
GT347_RS19275	COG0154	amidase activity
GT347_RS19295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GT347_RS19300	COG0277	FAD linked oxidase domain protein
GT347_RS19310	COG1295	ribonuclease BN
GT347_RS19320	COG0516	GMP reductase activity
GT347_RS19320	COG0517	IMP dehydrogenase activity
GT347_RS19335	COG1320	monovalent cation:proton antiporter activity
GT347_RS19340	COG2212	antiporter activity
GT347_RS19345	COG1863	multisubunit Na H antiporter MnhE subunit
GT347_RS19350	COG0651	ATP synthesis coupled electron transport
GT347_RS19355	COG1006	Multisubunit Na H antiporter MnhC subunit
GT347_RS19360	COG2111	Na H antiporter
GT347_RS19360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GT347_RS19375	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GT347_RS19395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GT347_RS19400	COG0287	Prephenate dehydrogenase
GT347_RS19410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GT347_RS19425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GT347_RS19440	COG1187	pseudouridine synthase activity
GT347_RS19475	COG3852	Histidine kinase
GT347_RS19485	COG0708	Exodeoxyribonuclease III
GT347_RS19505	COG1216	Glycosyl transferase, family 2
GT347_RS19510	COG1045	serine acetyltransferase
GT347_RS19585	COG2197	response regulator
GT347_RS19590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GT347_RS19600	COG2198	Histidine kinase
GT347_RS19600	COG0784	Response regulator, receiver
GT347_RS19600	COG5002	protein histidine kinase activity
GT347_RS19625	COG2207	Transcriptional regulator
GT347_RS19640	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GT347_RS19650	COG4794	Type iii secretion
GT347_RS19730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GT347_RS19750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GT347_RS19755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GT347_RS19765	COG2808	Putative FMN-binding domain
GT347_RS19770	COG1609	Transcriptional regulator
GT347_RS19780	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GT347_RS19785	COG1289	transmembrane transporter activity
GT347_RS19790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GT347_RS19795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GT347_RS19800	COG0741	lytic transglycosylase activity
GT347_RS19815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GT347_RS19840	COG0688	phosphatidylethanolamine metabolic process
GT347_RS19855	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS19860	COG2072	flavoprotein involved in K transport
GT347_RS19865	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS19875	COG4172	Belongs to the ABC transporter superfamily
GT347_RS19880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS19885	COG0601	transmembrane transport
GT347_RS19890	COG0747	negative chemotaxis
GT347_RS19900	COG0322	excinuclease ABC activity
GT347_RS19920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_RS19930	COG3437	response regulator, receiver
GT347_RS19955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GT347_RS19960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GT347_RS19985	COG0583	DNA-binding transcription factor activity
GT347_RS19990	COG1960	acyl-CoA dehydrogenase activity
GT347_RS19995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS20005	COG1295	ribonuclease BN
GT347_RS20005	COG1959	2 iron, 2 sulfur cluster binding
GT347_RS20040	COG0683	leucine binding
GT347_RS20440	COG0425	Belongs to the sulfur carrier protein TusA family
GT347_RS20445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GT347_RS20475	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GT347_RS20490	COG0477	Major facilitator Superfamily
GT347_RS20500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GT347_RS20505	COG0358	DNA primase activity
GT347_RS20510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GT347_RS20535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GT347_RS20555	COG3959	Transketolase, thiamine diphosphate binding domain
GT347_RS20560	COG3958	Transketolase
GT347_RS20575	COG1442	glycosyl transferase family 8
GT347_RS20575	COG1216	Glycosyl transferase, family 2
GT347_RS20625	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT347_RS20640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GT347_RS20655	COG3540	Alkaline phosphatase
GT347_RS20680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_RS20685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GT347_RS20690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GT347_RS20695	COG4988	ABC transporter
GT347_RS20705	COG1294	oxidase, subunit
GT347_RS20715	COG3047	cAMP biosynthetic process
GT347_RS20730	COG0583	DNA-binding transcription factor activity
GT347_RS20735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS20745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GT347_RS20755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS20760	COG1960	acyl-CoA dehydrogenase activity
GT347_RS20780	COG1301	dicarboxylic acid transport
GT347_RS20810	COG3618	amidohydrolase
GT347_RS20815	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS20835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS20850	COG4172	Belongs to the ABC transporter superfamily
GT347_RS20855	COG1446	asparaginase
GT347_RS20885	COG0583	DNA-binding transcription factor activity
GT347_RS20905	COG2267	carboxylic ester hydrolase activity
GT347_RS20910	COG3706	GGDEF domain
GT347_RS20940	COG0583	DNA-binding transcription factor activity
GT347_RS20945	COG0667	Aldo Keto reductase
GT347_RS20960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_RS20970	COG0583	DNA-binding transcription factor activity
GT347_RS20975	COG3781	membrane
GT347_RS21005	COG4302	ethanolamine ammonia-lyase activity
GT347_RS21025	COG0583	DNA-binding transcription factor activity
GT347_RS21030	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS21045	COG2207	Transcriptional regulator
GT347_RS21050	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS21055	COG0784	Response regulator, receiver
GT347_RS21055	COG4191	Histidine kinase
GT347_RS21060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_RS21070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GT347_RS21085	COG1129	ABC transporter
GT347_RS21120	COG0583	DNA-binding transcription factor activity
GT347_RS21135	COG1283	sodium-dependent phosphate transmembrane transporter activity
GT347_RS21140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GT347_RS21150	COG0196	riboflavin kinase activity
GT347_RS21160	COG3132	Protein of unknown function, DUF480
GT347_RS21165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GT347_RS21175	COG0745	RESPONSE REGULATOR receiver
GT347_RS21180	COG2205	protein histidine kinase activity
GT347_RS21185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GT347_RS21185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GT347_RS21195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GT347_RS21200	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GT347_RS21205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GT347_RS21210	COG0492	ferredoxin-NADP+ reductase activity
GT347_RS21220	COG1674	ftsk spoiiie
GT347_RS21225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GT347_RS21230	COG0038	chloride channel
GT347_RS21240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GT347_RS21245	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS21270	COG1392	Phosphate transport regulator
GT347_RS21275	COG0306	phosphate transporter
GT347_RS21290	COG0228	four-way junction DNA binding
GT347_RS21295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GT347_RS21300	COG0336	Belongs to the RNA methyltransferase TrmD family
GT347_RS21305	COG0335	large ribosomal subunit rRNA binding
GT347_RS21315	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GT347_RS21325	COG1162	GTPase activity
GT347_RS21330	COG2154	pterin-4-alpha-carbinolamine dehydratase
GT347_RS21335	COG0501	Belongs to the peptidase M48B family
GT347_RS21340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GT347_RS21345	COG0513	Belongs to the DEAD box helicase family
GT347_RS21350	COG5001	Diguanylate cyclase
GT347_RS21350	COG3300	MHYT domain
GT347_RS21355	COG2814	Major facilitator Superfamily
GT347_RS21400	COG1595	DNA-templated transcription, initiation
GT347_RS21405	COG3712	iron ion homeostasis
GT347_RS21410	COG4774	siderophore transport
GT347_RS21415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GT347_RS21465	COG1522	sequence-specific DNA binding
GT347_RS21470	COG0028	Belongs to the TPP enzyme family
GT347_RS21480	COG2146	nitrite reductase [NAD(P)H] activity
GT347_RS21485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GT347_RS21490	COG0583	DNA-binding transcription factor activity
GT347_RS21520	COG0671	phosphoesterase, PA-phosphatase related
GT347_RS21525	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GT347_RS21530	COG2076	Multidrug Resistance protein
GT347_RS21540	COG1215	transferase activity, transferring glycosyl groups
GT347_RS21545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GT347_RS21545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GT347_RS21555	COG0726	polysaccharide deacetylase
GT347_RS21590	COG3712	iron ion homeostasis
GT347_RS21600	COG0390	transport system, permease component
GT347_RS21605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GT347_RS21630	COG0784	Response regulator, receiver
GT347_RS21630	COG4191	Histidine kinase
GT347_RS21640	COG0745	RESPONSE REGULATOR receiver
GT347_RS21645	COG0642	Histidine kinase
GT347_RS21650	COG4251	negative regulation of phosphorylation
GT347_RS21655	COG0745	RESPONSE REGULATOR receiver
GT347_RS21660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_RS21670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_RS21695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GT347_RS21700	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS21710	COG1802	Transcriptional regulator
GT347_RS21725	COG2353	YceI-like domain
GT347_RS21770	COG1595	DNA-templated transcription, initiation
GT347_RS21785	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS21790	COG0583	DNA-binding transcription factor activity
GT347_RS21795	COG0583	DNA-binding transcription factor activity
GT347_RS21810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GT347_RS21870	COG1280	lysine exporter protein (LysE YggA)
GT347_RS21920	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS21955	COG1309	transcriptional regulator
GT347_RS21980	COG4172	Belongs to the ABC transporter superfamily
GT347_RS21985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GT347_RS21995	COG0747	negative chemotaxis
GT347_RS22010	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS22015	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS22025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS22030	COG0583	DNA-binding transcription factor activity
GT347_RS22060	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS22085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GT347_RS22105	COG0745	RESPONSE REGULATOR receiver
GT347_RS22120	COG2194	sulfuric ester hydrolase activity
GT347_RS22170	COG3800	Transcriptional regulator
GT347_RS22170	COG1396	sequence-specific DNA binding
GT347_RS22185	COG2376	Dihydroxyacetone kinase
GT347_RS22190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS22225	COG3246	L-lysine catabolic process to acetate
GT347_RS22230	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_RS22235	COG0583	DNA-binding transcription factor activity
GT347_RS22255	COG3186	Phenylalanine-4-hydroxylase
GT347_RS22275	COG5001	Diguanylate cyclase
GT347_RS22275	COG5002	protein histidine kinase activity
GT347_RS22275	COG3447	MASE1 domain protein
GT347_RS22305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS22310	COG1024	Enoyl-CoA hydratase
GT347_RS22315	COG1960	acyl-CoA dehydrogenase activity
GT347_RS22320	COG1960	acyl-CoA dehydrogenase activity
GT347_RS22325	COG0183	Belongs to the thiolase family
GT347_RS22330	COG1024	Enoyl-CoA hydratase
GT347_RS22330	COG1250	3-hydroxyacyl-CoA dehydrogenase
GT347_RS22335	COG0583	DNA-binding transcription factor activity
GT347_RS22405	COG0745	RESPONSE REGULATOR receiver
GT347_RS22420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT347_RS22425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT347_RS22435	COG0129	dihydroxy-acid dehydratase activity
GT347_RS22440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS22450	COG0583	DNA-binding transcription factor activity
GT347_RS22460	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS22475	COG1538	Outer membrane efflux protein
GT347_RS22515	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS22525	COG1116	anion transmembrane transporter activity
GT347_RS22530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS22560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS22605	COG1858	cytochrome C peroxidase
GT347_RS22625	COG1024	Enoyl-CoA hydratase
GT347_RS22630	COG1960	acyl-CoA dehydrogenase activity
GT347_RS22640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GT347_RS22650	COG0516	GMP reductase activity
GT347_RS22660	COG0210	DNA helicase
GT347_RS22670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GT347_RS22710	COG0165	Argininosuccinate lyase
GT347_RS22715	COG0745	RESPONSE REGULATOR receiver
GT347_RS22720	COG0642	Histidine kinase
GT347_RS22750	COG3634	alkyl hydroperoxide reductase activity
GT347_RS22760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GT347_RS22780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GT347_RS22800	COG0193	aminoacyl-tRNA hydrolase activity
GT347_RS22820	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS22830	COG2721	sulfolactate sulfo-lyase activity
GT347_RS22835	COG2186	Transcriptional regulator
GT347_RS22840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GT347_RS22845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS22855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GT347_RS22875	COG0489	protein tyrosine kinase activity
GT347_RS22915	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS22935	COG0243	molybdopterin cofactor binding
GT347_RS22950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GT347_RS22975	COG1538	Outer membrane efflux protein
GT347_RS22985	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GT347_RS23000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GT347_RS23005	COG2890	protein-(glutamine-N5) methyltransferase activity
GT347_RS23010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GT347_RS23015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GT347_RS23030	COG0584	glycerophosphoryl diester phosphodiesterase
GT347_RS23035	COG3842	ATPase activity
GT347_RS23050	COG1653	transport
GT347_RS23055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GT347_RS23065	COG3720	iron ion transport
GT347_RS23070	COG3733	amine oxidase
GT347_RS23090	COG0583	DNA-binding transcription factor activity
GT347_RS23105	COG4166	transmembrane transport
GT347_RS23115	COG3842	ATPase activity
GT347_RS23120	COG1176	ABC-type spermidine putrescine transport system, permease component I
GT347_RS23125	COG1177	transmembrane transport
GT347_RS23140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS23155	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GT347_RS23160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GT347_RS23165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GT347_RS23170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS23180	COG2267	carboxylic ester hydrolase activity
GT347_RS23185	COG3485	protocatechuate 3,4-dioxygenase
GT347_RS23190	COG3485	protocatechuate 3,4-dioxygenase
GT347_RS23195	COG0583	DNA-binding transcription factor activity
GT347_RS23215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS23230	COG0028	Belongs to the TPP enzyme family
GT347_RS23240	COG0477	Major facilitator Superfamily
GT347_RS23255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GT347_RS23265	COG1473	amidohydrolase
GT347_RS23270	COG0583	DNA-binding transcription factor activity
GT347_RS23275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GT347_RS23295	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GT347_RS23330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT347_RS23330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GT347_RS23335	COG0513	Belongs to the DEAD box helicase family
GT347_RS23350	COG0488	(ABC) transporter
GT347_RS23360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GT347_RS23370	COG4977	sequence-specific DNA binding
GT347_RS23375	COG0372	Belongs to the citrate synthase family
GT347_RS23380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GT347_RS23385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GT347_RS23395	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GT347_RS23400	COG2009	succinate dehydrogenase
GT347_RS23405	COG2188	Transcriptional regulator
GT347_RS23410	COG0039	L-malate dehydrogenase activity
GT347_RS23415	COG4106	trans-aconitate 2-methyltransferase activity
GT347_RS23445	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GT347_RS23465	COG0544	peptidyl-prolyl cis-trans isomerase activity
GT347_RS23470	COG0740	serine-type endopeptidase activity
GT347_RS23475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GT347_RS23480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GT347_RS23500	COG5001	Diguanylate cyclase
GT347_RS23500	COG3447	MASE1 domain protein
GT347_RS23500	COG5002	protein histidine kinase activity
GT347_RS23515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GT347_RS23525	COG1858	cytochrome C peroxidase
GT347_RS23540	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS23545	COG3284	Transcriptional regulator
GT347_RS23560	COG0114	fumarate hydratase activity
GT347_RS23570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GT347_RS23580	COG4654	Cytochrome c, class I
GT347_RS23590	COG0129	dihydroxy-acid dehydratase activity
GT347_RS23595	COG0583	DNA-binding transcription factor activity
GT347_RS23600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GT347_RS23605	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GT347_RS23615	COG0667	Aldo Keto reductase
GT347_RS23620	COG3437	response regulator, receiver
GT347_RS23620	COG3850	Histidine kinase
GT347_RS23620	COG4999	Histidine kinase
GT347_RS23620	COG2205	protein histidine kinase activity
GT347_RS23625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GT347_RS23650	COG1666	GTP binding
GT347_RS23655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GT347_RS23670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GT347_RS23680	COG0762	integral membrane protein
GT347_RS23685	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GT347_RS23690	COG0159	tryptophan synthase activity
GT347_RS23695	COG0133	tryptophan synthase activity
GT347_RS23700	COG0135	phosphoribosylanthranilate isomerase activity
GT347_RS23705	COG0101	tRNA pseudouridine synthase activity
GT347_RS23725	COG4251	negative regulation of phosphorylation
GT347_RS23725	COG3706	GGDEF domain
GT347_RS23725	COG2203	Gaf domain
GT347_RS23725	COG5001	Diguanylate cyclase
GT347_RS23730	COG0473	3-isopropylmalate dehydrogenase activity
GT347_RS23735	COG0066	3-isopropylmalate dehydratase activity
GT347_RS23740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_RS23750	COG0484	heat shock protein binding
GT347_RS23755	COG0443	Heat shock 70 kDa protein
GT347_RS23760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GT347_RS23765	COG0360	Binds together with S18 to 16S ribosomal RNA
GT347_RS23775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GT347_RS23780	COG0359	binds to the 23S rRNA
GT347_RS23785	COG0305	Participates in initiation and elongation during chromosome replication
GT347_RS23800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT347_RS23810	COG0436	Aminotransferase
GT347_RS23830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GT347_RS23835	COG1763	Mo-molybdopterin cofactor biosynthetic process
GT347_RS23850	COG0314	molybdopterin synthase activity
GT347_RS23860	COG4191	Histidine kinase
GT347_RS23860	COG0784	Response regulator, receiver
GT347_RS23870	COG0567	Dehydrogenase, E1 component
GT347_RS23875	COG0508	dehydrogenase complex catalyzes the overall conversion of
GT347_RS23890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GT347_RS23895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GT347_RS23910	COG1199	ATP-dependent helicase activity
GT347_RS23920	COG0564	pseudouridine synthase activity
GT347_RS23940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GT347_RS23955	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GT347_RS23960	COG0124	histidyl-tRNA synthetase
GT347_RS23975	COG1160	GTP binding
GT347_RS23980	COG1923	regulation of RNA biosynthetic process
GT347_RS23985	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GT347_RS23990	COG0330	HflC and HflK could
GT347_RS23995	COG0330	HflC and HflK could
GT347_RS24005	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GT347_RS24010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GT347_RS24020	COG0455	bacterial-type flagellum organization
GT347_RS24025	COG3706	GGDEF domain
GT347_RS24025	COG0745	RESPONSE REGULATOR receiver
GT347_RS24030	COG1846	Transcriptional regulator
GT347_RS24035	COG1538	Outer membrane efflux protein
GT347_RS24040	COG1566	PFAM secretion protein HlyD family protein
GT347_RS24075	COG4968	Prepilin-type N-terminal cleavage methylation domain
GT347_RS24080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GT347_RS24105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GT347_RS24120	COG1454	alcohol dehydrogenase
GT347_RS24125	COG2130	NADP-dependent
GT347_RS24130	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS24140	COG0628	permease
GT347_RS24160	COG1722	exodeoxyribonuclease VII activity
GT347_RS24165	COG0142	geranyltranstransferase activity
GT347_RS24170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GT347_RS24175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GT347_RS24190	COG0243	molybdopterin cofactor binding
GT347_RS24255	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS24265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GT347_RS24270	COG3706	GGDEF domain
GT347_RS24275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GT347_RS24280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GT347_RS24285	COG0583	DNA-binding transcription factor activity
GT347_RS24290	COG1741	Belongs to the pirin family
GT347_RS24300	COG1741	Belongs to the pirin family
GT347_RS24310	COG0025	NhaP-type Na H and K H
GT347_RS24315	COG0477	Major facilitator Superfamily
GT347_RS24345	COG0559	Belongs to the binding-protein-dependent transport system permease family
GT347_RS24360	COG0443	Heat shock 70 kDa protein
GT347_RS24375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GT347_RS24380	COG0542	response to heat
GT347_RS24390	COG2925	Exonuclease
GT347_RS24415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GT347_RS24420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GT347_RS24425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GT347_RS24430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GT347_RS24435	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GT347_RS24445	COG0776	regulation of translation
GT347_RS24480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GT347_RS24510	COG2814	Major facilitator Superfamily
GT347_RS24520	COG0583	DNA-binding transcription factor activity
GT347_RS24535	COG3387	PFAM Glycoside hydrolase 15-related
GT347_RS24560	COG1802	Transcriptional regulator
GT347_RS24565	COG2084	Dehydrogenase
GT347_RS24575	COG2186	Transcriptional regulator
GT347_RS24580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS24585	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS24590	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS24640	COG2721	sulfolactate sulfo-lyase activity
GT347_RS24650	COG0473	3-isopropylmalate dehydrogenase activity
GT347_RS24655	COG0583	DNA-binding transcription factor activity
GT347_RS24665	COG0583	DNA-binding transcription factor activity
GT347_RS24670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GT347_RS24700	COG1451	nucleotide metabolic process
GT347_RS24715	COG4172	Belongs to the ABC transporter superfamily
GT347_RS24730	COG0747	negative chemotaxis
GT347_RS24755	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS24765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GT347_RS24775	COG2885	chlorophyll binding
GT347_RS24800	COG2197	response regulator
GT347_RS24815	COG0515	serine threonine protein kinase
GT347_RS24820	COG0840	transmembrane signaling receptor activity
GT347_RS24845	COG0492	ferredoxin-NADP+ reductase activity
GT347_RS24855	COG0028	Belongs to the TPP enzyme family
GT347_RS24860	COG1414	Transcriptional regulator
GT347_RS24870	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS24895	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS24945	COG2072	flavoprotein involved in K transport
GT347_RS24955	COG0438	transferase activity, transferring glycosyl groups
GT347_RS24960	COG2144	transferase activity, transferring acyl groups
GT347_RS24985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS25020	COG0583	DNA-binding transcription factor activity
GT347_RS25040	COG0625	glutathione transferase activity
GT347_RS25065	COG1360	Flagellar Motor Protein
GT347_RS25080	COG0631	protein serine/threonine phosphatase activity
GT347_RS25105	COG3501	Rhs element vgr protein
GT347_RS25220	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
GT347_RS25225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GT347_RS25235	COG1595	DNA-templated transcription, initiation
GT347_RS25240	COG4944	Protein of unknown function (DUF1109)
GT347_RS25255	COG3093	addiction module antidote protein HigA
GT347_RS25270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GT347_RS25275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GT347_RS25285	COG0038	chloride channel
GT347_RS25295	COG0583	DNA-binding transcription factor activity
GT347_RS25355	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS25360	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
GT347_RS25365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GT347_RS25375	COG3128	pkhd-type hydroxylase
GT347_RS25400	COG0583	DNA-binding transcription factor activity
GT347_RS25405	COG1024	Enoyl-CoA hydratase
GT347_RS25415	COG1960	acyl-CoA dehydrogenase activity
GT347_RS25435	COG0386	Belongs to the glutathione peroxidase family
GT347_RS25445	COG2011	ABC-type metal ion transport system permease component
GT347_RS25455	COG1045	serine acetyltransferase
GT347_RS25510	COG3706	GGDEF domain
GT347_RS25535	COG0235	Class ii aldolase
GT347_RS25540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GT347_RS25545	COG0697	spore germination
GT347_RS25565	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS25580	COG4948	Mandelate Racemase Muconate Lactonizing
GT347_RS25655	COG3550	peptidyl-serine autophosphorylation
GT347_RS25665	COG0784	Response regulator, receiver
GT347_RS25665	COG4191	Histidine kinase
GT347_RS25695	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GT347_RS25705	COG1741	Belongs to the pirin family
GT347_RS25710	COG0583	DNA-binding transcription factor activity
GT347_RS25730	COG1840	ABC-type Fe3 transport system, periplasmic component
GT347_RS25735	COG3842	ATPase activity
GT347_RS25755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GT347_RS25765	COG2828	Protein conserved in bacteria
GT347_RS25770	COG1733	regulation of RNA biosynthetic process
GT347_RS25775	COG0702	epimerase
GT347_RS25785	COG1595	DNA-templated transcription, initiation
GT347_RS25835	COG1012	belongs to the aldehyde dehydrogenase family
GT347_RS25855	COG0243	molybdopterin cofactor binding
GT347_RS25860	COG3279	Response regulator of the LytR AlgR family
GT347_RS25865	COG3275	phosphorelay sensor kinase activity
GT347_RS25880	COG1968	undecaprenyl-diphosphatase activity
GT347_RS25895	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GT347_RS25915	COG2171	N-acyltransferase activity
GT347_RS25930	COG1289	transmembrane transporter activity
GT347_RS25945	COG1045	serine acetyltransferase
GT347_RS25960	COG0521	Mo-molybdopterin cofactor biosynthetic process
GT347_RS25965	COG3028	Belongs to the UPF0307 family
GT347_RS25970	COG0312	modulator of DNA gyrase
GT347_RS25985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GT347_RS25990	COG2081	HI0933 family
GT347_RS26015	COG1609	Transcriptional regulator
GT347_RS26035	COG0395	ABC-type sugar transport system, permease component
GT347_RS26040	COG1063	alcohol dehydrogenase
GT347_RS26045	COG3842	ATPase activity
GT347_RS26050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GT347_RS26055	COG3684	Belongs to the aldolase LacD family
GT347_RS26060	COG0730	response to heat
GT347_RS26085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GT347_RS26090	COG0243	molybdopterin cofactor binding
GT347_RS26105	COG1116	anion transmembrane transporter activity
GT347_RS26110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GT347_RS26115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GT347_RS26125	COG3707	response regulator
GT347_RS26135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GT347_RS26145	COG0683	leucine binding
GT347_RS26155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GT347_RS26160	COG1185	polyribonucleotide nucleotidyltransferase activity
GT347_RS26165	COG0604	alcohol dehydrogenase
GT347_RS26165	COG3321	synthase
GT347_RS26170	COG0149	triose-phosphate isomerase activity
GT347_RS26185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_RS26190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_RS26195	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_RS26200	COG0649	NAD binding
GT347_RS26205	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GT347_RS26210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GT347_RS26215	COG1034	ATP synthesis coupled electron transport
GT347_RS26220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GT347_RS26225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GT347_RS26235	COG0713	ATP synthesis coupled electron transport
GT347_RS26250	COG1007	ATP synthesis coupled electron transport
GT347_RS26275	COG3237	CsbD-like
GT347_RS26285	COG0626	cystathionine gamma-synthase activity
GT347_RS26295	COG4181	ATPase activity
GT347_RS26300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GT347_RS26305	COG2951	lytic endotransglycosylase activity
GT347_RS26320	COG0714	Associated with various cellular activities
GT347_RS26330	COG3264	Mechanosensitive ion channel
GT347_RS26330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GT347_RS26370	COG3608	succinylglutamate desuccinylase aspartoacylase
GT347_RS26370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GT347_RS26380	COG0840	transmembrane signaling receptor activity
GT347_RS26405	COG4774	siderophore transport
GT347_RS26425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GT347_RS26435	COG2917	probably involved in intracellular septation
GT347_RS26440	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GT347_RS26445	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GT347_RS26455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GT347_RS26475	COG2814	Major facilitator Superfamily
GT347_RS26485	COG1522	sequence-specific DNA binding
GT347_RS26490	COG0626	cystathionine gamma-synthase activity
GT347_RS26495	COG2072	flavoprotein involved in K transport
GT347_RS26530	COG0765	amino acid transport
GT347_RS26535	COG0765	amino acid transport
GT347_RS26555	COG1304	FMN binding
GT347_RS26565	COG0589	response to stress
GT347_RS26570	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS26575	COG0564	pseudouridine synthase activity
GT347_RS26585	COG0596	Alpha beta hydrolase
GT347_RS26605	COG0590	tRNA wobble adenosine to inosine editing
GT347_RS26610	COG1619	proteins homologs of microcin C7 resistance protein MccF
GT347_RS26615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GT347_RS26635	COG3265	gluconokinase activity
GT347_RS26640	COG2271	Major facilitator Superfamily
GT347_RS26650	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS26700	COG0114	fumarate hydratase activity
GT347_RS26710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GT347_RS26715	COG2188	Transcriptional regulator
GT347_RS26775	COG0583	DNA-binding transcription factor activity
GT347_RS26790	COG0145	ligase activity
GT347_RS26795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GT347_RS26820	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GT347_RS26840	COG0431	NADPH-dependent FMN reductase
GT347_RS26845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GT347_RS26850	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GT347_RS26855	COG2080	2 iron, 2 sulfur cluster binding
GT347_RS26865	COG0454	-acetyltransferase
GT347_RS26880	COG0412	Dienelactone hydrolase
GT347_RS26900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GT347_RS26910	COG3181	Tripartite tricarboxylate transporter family receptor
GT347_RS26920	COG2079	MmgE PrpD family protein
GT347_RS26935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GT347_RS26965	COG0670	Belongs to the BI1 family
GT347_RS26975	COG0583	DNA-binding transcription factor activity
GT347_RS26980	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
GT347_RS26995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GT347_RS27015	COG0747	negative chemotaxis
GT347_RS27035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GT347_RS27070	COG1802	Transcriptional regulator
GT347_RS27090	COG2814	Major facilitator Superfamily
GT347_RS27095	COG1733	regulation of RNA biosynthetic process
GT347_RS27120	COG0084	hydrolase, TatD family'
GT347_RS27135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GT347_RS27140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GT347_RS27145	COG1192	Involved in chromosome partitioning
GT347_RS27210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GT347_RS27215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair