locus-tag	class	description
AYJ57_RS00020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYJ57_RS00040	COG0440	acetolactate synthase activity
AYJ57_RS00050	COG0028	Belongs to the TPP enzyme family
AYJ57_RS00070	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ57_RS00080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS00095	COG4638	Rieske (2fe-2S)
AYJ57_RS00100	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AYJ57_RS00105	COG0028	Belongs to the TPP enzyme family
AYJ57_RS00140	COG4656	Part of a membrane complex involved in electron transport
AYJ57_RS00145	COG2878	Part of a membrane complex involved in electron transport
AYJ57_RS00155	COG0633	Ferredoxin
AYJ57_RS00160	COG3086	response to oxidative stress
AYJ57_RS00180	COG0716	FMN binding
AYJ57_RS00190	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AYJ57_RS00195	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AYJ57_RS00225	COG5420	small protein containing a coiled-coil domain
AYJ57_RS00255	COG1104	cysteine desulfurase activity
AYJ57_RS00275	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYJ57_RS00280	COG4149	molybdate abc transporter
AYJ57_RS00285	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ57_RS00300	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYJ57_RS00305	COG3604	Transcriptional regulator
AYJ57_RS00315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYJ57_RS00360	COG0583	DNA-binding transcription factor activity
AYJ57_RS00370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ57_RS00380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYJ57_RS00385	COG4235	cytochrome complex assembly
AYJ57_RS00390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_RS00410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_RS00410	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ57_RS00430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYJ57_RS00430	COG1648	precorrin-2 dehydrogenase activity
AYJ57_RS00440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_RS00465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ57_RS00475	COG3811	Belongs to the UPF0386 family
AYJ57_RS00480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYJ57_RS00485	COG0415	Belongs to the DNA photolyase family
AYJ57_RS00495	COG0494	nUDIX hydrolase
AYJ57_RS00505	COG3264	Mechanosensitive ion channel
AYJ57_RS00505	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AYJ57_RS00510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AYJ57_RS00525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AYJ57_RS00540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYJ57_RS00550	COG0166	Belongs to the GPI family
AYJ57_RS00575	COG3108	Peptidase M15
AYJ57_RS00585	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_RS00600	COG0431	NADPH-dependent FMN reductase
AYJ57_RS00610	COG2354	Protein conserved in bacteria
AYJ57_RS00620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYJ57_RS00650	COG0033	Phosphoglucomutase
AYJ57_RS00665	COG0297	glycogen (starch) synthase activity
AYJ57_RS00670	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AYJ57_RS00675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AYJ57_RS00680	COG0058	SHG alpha-glucan phosphorylase activity
AYJ57_RS00685	COG0837	glucose binding
AYJ57_RS00690	COG2723	6-phospho-beta-galactosidase activity
AYJ57_RS00695	COG1609	Transcriptional regulator
AYJ57_RS00700	COG1653	transport
AYJ57_RS00705	COG1175	transmembrane transport
AYJ57_RS00710	COG0395	ABC-type sugar transport system, permease component
AYJ57_RS00715	COG0366	Alpha amylase catalytic
AYJ57_RS00720	COG3842	ATPase activity
AYJ57_RS00725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYJ57_RS00735	COG1024	Enoyl-CoA hydratase
AYJ57_RS00745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AYJ57_RS00770	COG1492	cobalamin metabolic process
AYJ57_RS00780	COG0538	isocitrate dehydrogenase activity
AYJ57_RS00790	COG0840	transmembrane signaling receptor activity
AYJ57_RS00795	COG2814	Major facilitator Superfamily
AYJ57_RS00810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AYJ57_RS00815	COG1960	acyl-CoA dehydrogenase activity
AYJ57_RS00820	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS00825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS00835	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ57_RS00840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AYJ57_RS00845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYJ57_RS00855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYJ57_RS00870	COG2166	iron-sulfur cluster assembly
AYJ57_RS00875	COG0233	cytoplasmic translational termination
AYJ57_RS00880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYJ57_RS00890	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AYJ57_RS00895	COG0750	zinc metalloprotease
AYJ57_RS00910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ57_RS00915	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_RS00920	COG3494	Protein of unknown function (DUF1009)
AYJ57_RS00925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_RS00935	COG0433	COG0433 Predicted ATPase
AYJ57_RS00950	COG4166	transmembrane transport
AYJ57_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS00965	COG1573	uracil-dna glycosylase
AYJ57_RS00975	COG2313	pseudouridylate synthase activity
AYJ57_RS00980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_RS00985	COG2130	NADP-dependent
AYJ57_RS01000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AYJ57_RS01005	COG2197	response regulator
AYJ57_RS01010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AYJ57_RS01015	COG0052	Belongs to the universal ribosomal protein uS2 family
AYJ57_RS01035	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS01040	COG0704	Plays a role in the regulation of phosphate uptake
AYJ57_RS01045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYJ57_RS01050	COG0581	inorganic phosphate transmembrane transporter activity
AYJ57_RS01055	COG0573	inorganic phosphate transmembrane transporter activity
AYJ57_RS01065	COG5002	protein histidine kinase activity
AYJ57_RS01070	COG0626	cystathionine gamma-synthase activity
AYJ57_RS01085	COG0194	GDP metabolic process
AYJ57_RS01090	COG1561	YicC-like family, N-terminal region
AYJ57_RS01100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYJ57_RS01105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_RS01115	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYJ57_RS01130	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AYJ57_RS01140	COG2133	pyrroloquinoline quinone binding
AYJ57_RS01145	COG0442	prolyl-tRNA aminoacylation
AYJ57_RS01195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ57_RS01210	COG1278	Cold shock
AYJ57_RS01215	COG0259	pyridoxamine-phosphate oxidase activity
AYJ57_RS01220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYJ57_RS01230	COG0702	epimerase
AYJ57_RS01235	COG1733	regulation of RNA biosynthetic process
AYJ57_RS01240	COG0436	Aminotransferase
AYJ57_RS01250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYJ57_RS01265	COG2032	superoxide dismutase activity
AYJ57_RS01270	COG0517	IMP dehydrogenase activity
AYJ57_RS01270	COG1994	Peptidase M50
AYJ57_RS01275	COG1410	methionine synthase
AYJ57_RS01275	COG0646	methionine synthase
AYJ57_RS01290	COG5012	cobalamin binding
AYJ57_RS01310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYJ57_RS01315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AYJ57_RS01320	COG0134	indole-3-glycerol-phosphate synthase activity
AYJ57_RS01330	COG0303	'Molybdopterin
AYJ57_RS01335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYJ57_RS01340	COG0658	competence protein
AYJ57_RS01340	COG2333	competence protein COMEC
AYJ57_RS01345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ57_RS01355	COG1024	Enoyl-CoA hydratase
AYJ57_RS01365	COG3088	subunit of a heme lyase
AYJ57_RS01370	COG1138	Cytochrome C-type biogenesis protein
AYJ57_RS01380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AYJ57_RS01385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AYJ57_RS01385	COG3743	rRNA binding
AYJ57_RS01420	COG1238	metal cluster binding
AYJ57_RS01445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AYJ57_RS01450	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AYJ57_RS01485	COG2059	Chromate
AYJ57_RS01495	COG0114	fumarate hydratase activity
AYJ57_RS01515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYJ57_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_RS01560	COG0642	Histidine kinase
AYJ57_RS01570	COG1376	ErfK ybiS ycfS ynhG family protein
AYJ57_RS01580	COG1070	Carbohydrate kinase
AYJ57_RS01605	COG1175	transmembrane transport
AYJ57_RS01620	COG0546	phosphoglycolate phosphatase activity
AYJ57_RS01630	COG0805	protein transport
AYJ57_RS01635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYJ57_RS01640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYJ57_RS01645	COG2378	regulation of single-species biofilm formation
AYJ57_RS01655	COG3473	Maleate cis-trans isomerase
AYJ57_RS01660	COG0477	Major facilitator Superfamily
AYJ57_RS01670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYJ57_RS01680	COG0360	Binds together with S18 to 16S ribosomal RNA
AYJ57_RS01685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AYJ57_RS01690	COG0359	binds to the 23S rRNA
AYJ57_RS01700	COG0544	peptidyl-prolyl cis-trans isomerase activity
AYJ57_RS01705	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYJ57_RS01730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYJ57_RS01740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYJ57_RS01745	COG5265	(ABC) transporter
AYJ57_RS01770	COG3588	fructose-bisphosphate aldolase
AYJ57_RS01785	COG0785	Cytochrome C biogenesis protein
AYJ57_RS01790	COG1530	ribonuclease E activity
AYJ57_RS01800	COG2084	Dehydrogenase
AYJ57_RS01815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYJ57_RS01820	COG1923	regulation of RNA biosynthetic process
AYJ57_RS01825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ57_RS01830	COG0569	domain protein
AYJ57_RS01835	COG2204	response regulator
AYJ57_RS01840	COG5000	phosphorelay sensor kinase activity
AYJ57_RS01845	COG2204	response regulator
AYJ57_RS01850	COG3852	Histidine kinase
AYJ57_RS01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ57_RS01860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AYJ57_RS01860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AYJ57_RS01865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYJ57_RS01870	COG1546	Belongs to the CinA family
AYJ57_RS01875	COG2867	negative regulation of translational initiation
AYJ57_RS01880	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AYJ57_RS01890	COG3909	cytochrome
AYJ57_RS01895	COG2010	Cytochrome c
AYJ57_RS01905	COG2391	methyltransferase activity
AYJ57_RS01920	COG0785	Cytochrome C biogenesis protein
AYJ57_RS01945	COG3258	Cytochrome c
AYJ57_RS01950	COG0737	Belongs to the 5'-nucleotidase family
AYJ57_RS01955	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AYJ57_RS01970	COG0156	8-amino-7-oxononanoate synthase activity
AYJ57_RS01975	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AYJ57_RS01985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ57_RS01990	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYJ57_RS02000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYJ57_RS02005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AYJ57_RS02020	COG0482	sulfurtransferase activity
AYJ57_RS02035	COG2204	response regulator
AYJ57_RS02045	COG0047	phosphoribosylformylglycinamidine synthase activity
AYJ57_RS02050	COG1063	alcohol dehydrogenase
AYJ57_RS02055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AYJ57_RS02065	COG2326	polyphosphate kinase activity
AYJ57_RS02075	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS02090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AYJ57_RS02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_RS02105	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AYJ57_RS02110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AYJ57_RS02120	COG4974	Belongs to the 'phage' integrase family
AYJ57_RS02125	COG0528	UMP kinase activity
AYJ57_RS02130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AYJ57_RS02145	COG1858	cytochrome C peroxidase
AYJ57_RS02150	COG0741	lytic transglycosylase activity
AYJ57_RS02155	COG0629	single-stranded DNA binding
AYJ57_RS02165	COG4536	flavin adenine dinucleotide binding
AYJ57_RS02185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYJ57_RS02190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AYJ57_RS02200	COG2205	protein histidine kinase activity
AYJ57_RS02205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ57_RS02215	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS02260	COG0714	Associated with various cellular activities
AYJ57_RS02270	COG3119	arylsulfatase activity
AYJ57_RS02285	COG0753	catalase activity
AYJ57_RS02315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ57_RS02315	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ57_RS02320	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AYJ57_RS02325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AYJ57_RS02335	COG0697	spore germination
AYJ57_RS02345	COG0840	transmembrane signaling receptor activity
AYJ57_RS02345	COG0840	transmembrane signaling receptor activity
AYJ57_RS02360	COG1217	gtp-binding protein TYPA
AYJ57_RS02385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AYJ57_RS02415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYJ57_RS02430	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AYJ57_RS02435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYJ57_RS02455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYJ57_RS02470	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AYJ57_RS02475	COG1612	heme a metabolic process
AYJ57_RS02485	COG0454	-acetyltransferase
AYJ57_RS02485	COG0456	acetyltransferase
AYJ57_RS02490	COG0352	thiamine-phosphate diphosphorylase activity
AYJ57_RS02515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AYJ57_RS02520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AYJ57_RS02525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AYJ57_RS02550	COG2151	metal-sulfur cluster biosynthetic enzyme
AYJ57_RS02560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AYJ57_RS02565	COG0316	Belongs to the HesB IscA family
AYJ57_RS02570	COG0149	triose-phosphate isomerase activity
AYJ57_RS02580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS02585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYJ57_RS02590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_RS02615	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AYJ57_RS02625	COG1007	ATP synthesis coupled electron transport
AYJ57_RS02640	COG0713	ATP synthesis coupled electron transport
AYJ57_RS02660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AYJ57_RS02715	COG0649	NAD binding
AYJ57_RS02720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ57_RS02725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ57_RS02735	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_RS02735	COG1024	Enoyl-CoA hydratase
AYJ57_RS02745	COG0625	glutathione transferase activity
AYJ57_RS02755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYJ57_RS02760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ57_RS02770	COG1960	acyl-CoA dehydrogenase activity
AYJ57_RS02785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ57_RS02800	COG0513	Belongs to the DEAD box helicase family
AYJ57_RS02805	COG1764	response to oxidative stress
AYJ57_RS02815	COG1522	sequence-specific DNA binding
AYJ57_RS02825	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ57_RS02830	COG0175	sulfate reduction
AYJ57_RS02845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_RS02860	COG3181	Tripartite tricarboxylate transporter family receptor
AYJ57_RS02880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AYJ57_RS02890	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AYJ57_RS02910	COG0546	phosphoglycolate phosphatase activity
AYJ57_RS02915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AYJ57_RS02925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYJ57_RS02940	COG0719	Fe-S assembly protein
AYJ57_RS02945	COG0396	ATPase activity
AYJ57_RS02955	COG0393	Putative heavy-metal-binding
AYJ57_RS02965	COG0719	Fe-S assembly protein
AYJ57_RS02975	COG1959	2 iron, 2 sulfur cluster binding
AYJ57_RS02980	COG2945	thiolester hydrolase activity
AYJ57_RS02995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ57_RS03020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AYJ57_RS03030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ57_RS03035	COG0739	heme binding
AYJ57_RS03070	COG2814	Major facilitator Superfamily
AYJ57_RS03080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ57_RS03085	COG0215	cysteine-tRNA ligase activity
AYJ57_RS03100	COG2890	protein-(glutamine-N5) methyltransferase activity
AYJ57_RS03105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AYJ57_RS03115	COG0010	Belongs to the arginase family
AYJ57_RS03120	COG1473	amidohydrolase
AYJ57_RS03125	COG1473	amidohydrolase
AYJ57_RS03130	COG3956	TIGRFAM MazG family protein
AYJ57_RS03135	COG1840	ABC-type Fe3 transport system, periplasmic component
AYJ57_RS03140	COG3454	Phosphonate metabolism
AYJ57_RS03145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AYJ57_RS03155	COG4778	phosphonate C-P lyase system protein PhnL
AYJ57_RS03160	COG4107	phosphonate C-P lyase system protein PhnK
AYJ57_RS03165	COG3627	carbon phosphorus lyase activity
AYJ57_RS03175	COG3626	phosphonate metabolism
AYJ57_RS03185	COG3624	Phosphonate C-P lyase system protein PhnG
AYJ57_RS03190	COG2188	Transcriptional regulator
AYJ57_RS03195	COG3454	Phosphonate metabolism
AYJ57_RS03200	COG1879	ABC-type sugar transport system periplasmic component
AYJ57_RS03205	COG0840	transmembrane signaling receptor activity
AYJ57_RS03215	COG3639	organic phosphonate transmembrane transporter activity
AYJ57_RS03225	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AYJ57_RS03230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AYJ57_RS03250	COG0352	thiamine-phosphate diphosphorylase activity
AYJ57_RS03260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AYJ57_RS03265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYJ57_RS03290	COG1846	Transcriptional regulator
AYJ57_RS03295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_RS03310	COG2943	transferase activity, transferring hexosyl groups
AYJ57_RS03315	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AYJ57_RS03330	COG0154	amidase activity
AYJ57_RS03335	COG0444	Belongs to the ABC transporter superfamily
AYJ57_RS03340	COG4608	Belongs to the ABC transporter superfamily
AYJ57_RS03345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_RS03385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYJ57_RS03395	COG1414	Transcriptional regulator
AYJ57_RS03410	COG0330	HflC and HflK could
AYJ57_RS03415	COG0330	HflC and HflK could
AYJ57_RS03425	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AYJ57_RS03430	COG1760	l-serine dehydratase
AYJ57_RS03440	COG0456	acetyltransferase
AYJ57_RS03475	COG0375	protein maturation
AYJ57_RS03535	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AYJ57_RS03545	COG4191	Histidine kinase
AYJ57_RS03560	COG3845	ABC transporter
AYJ57_RS03565	COG4603	Belongs to the binding-protein-dependent transport system permease family
AYJ57_RS03570	COG1079	Belongs to the binding-protein-dependent transport system permease family
AYJ57_RS03575	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_RS03590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYJ57_RS03630	COG1136	(ABC) transporter
AYJ57_RS03640	COG2353	YceI-like domain
AYJ57_RS03645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYJ57_RS03655	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AYJ57_RS03665	COG1132	(ABC) transporter
AYJ57_RS03675	COG3001	Fructosamine kinase
AYJ57_RS03685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AYJ57_RS03705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYJ57_RS03720	COG0405	Gamma-glutamyltransferase
AYJ57_RS03745	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS03750	COG1396	sequence-specific DNA binding
AYJ57_RS03750	COG3800	Transcriptional regulator
AYJ57_RS03775	COG0410	ABC transporter
AYJ57_RS03780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ57_RS03795	COG0439	Biotin carboxylase
AYJ57_RS03800	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AYJ57_RS03830	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AYJ57_RS03835	COG0740	serine-type endopeptidase activity
AYJ57_RS03840	COG1230	cation diffusion facilitator family transporter
AYJ57_RS03865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ57_RS03870	COG1121	(ABC) transporter
AYJ57_RS03875	COG0735	belongs to the Fur family
AYJ57_RS03885	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AYJ57_RS03890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ57_RS03895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ57_RS03900	COG1120	ATPase activity
AYJ57_RS03910	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AYJ57_RS03915	COG1984	allophanate hydrolase subunit 2
AYJ57_RS03920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AYJ57_RS03930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AYJ57_RS03935	COG1530	ribonuclease E activity
AYJ57_RS03945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AYJ57_RS03950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYJ57_RS03975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYJ57_RS03990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYJ57_RS04005	COG2954	triphosphatase activity
AYJ57_RS04010	COG1192	Involved in chromosome partitioning
AYJ57_RS04030	COG0358	DNA primase activity
AYJ57_RS04035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYJ57_RS04055	COG0729	surface antigen
AYJ57_RS04070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AYJ57_RS04075	COG0830	nickel cation binding
AYJ57_RS04080	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AYJ57_RS04090	COG0804	urea catabolic process
AYJ57_RS04100	COG2010	Cytochrome c
AYJ57_RS04100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYJ57_RS04115	COG0832	Belongs to the urease beta subunit family
AYJ57_RS04120	COG0831	urea catabolic process
AYJ57_RS04125	COG0829	nickel cation binding
AYJ57_RS04130	COG1720	tRNA m6t6A37 methyltransferase activity
AYJ57_RS04135	COG0800	Aldolase
AYJ57_RS04140	COG3734	2-keto-3-deoxy-galactonokinase
AYJ57_RS04160	COG2308	Evidence 4 Homologs of previously reported genes of
AYJ57_RS04160	COG2307	Protein conserved in bacteria
AYJ57_RS04170	COG4221	oxidoreductase activity
AYJ57_RS04180	COG0432	Pfam Uncharacterised protein family UPF0047
AYJ57_RS04185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AYJ57_RS04190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ57_RS04190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ57_RS04195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ57_RS04230	COG4166	transmembrane transport
AYJ57_RS04235	COG4174	ABC transporter (Permease)
AYJ57_RS04240	COG4239	(ABC) transporter, permease
AYJ57_RS04245	COG4172	Belongs to the ABC transporter superfamily
AYJ57_RS04250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYJ57_RS04255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYJ57_RS04260	COG5507	3-demethylubiquinone-9 3-methyltransferase
AYJ57_RS04290	COG2010	Cytochrome c
AYJ57_RS04295	COG0583	DNA-binding transcription factor activity
AYJ57_RS04300	COG0348	domain, Protein
AYJ57_RS04330	COG1522	sequence-specific DNA binding
AYJ57_RS04335	COG0686	Belongs to the AlaDH PNT family
AYJ57_RS04340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AYJ57_RS04345	COG1970	mechanosensitive ion channel activity
AYJ57_RS04380	COG0768	penicillin binding
AYJ57_RS04385	COG0772	Belongs to the SEDS family
AYJ57_RS04390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_RS04400	COG0659	secondary active sulfate transmembrane transporter activity
AYJ57_RS04410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AYJ57_RS04415	COG1280	lysine exporter protein (LysE YggA)
AYJ57_RS04425	COG0534	Mate efflux family protein
AYJ57_RS04455	COG0625	glutathione transferase activity
AYJ57_RS04470	COG0604	alcohol dehydrogenase
AYJ57_RS04475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AYJ57_RS04475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AYJ57_RS04485	COG0813	purine-nucleoside phosphorylase activity
AYJ57_RS04495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AYJ57_RS04530	COG2030	dehydratase
AYJ57_RS04555	COG1732	Glycine betaine
AYJ57_RS04560	COG1174	glycine betaine transport
AYJ57_RS04565	COG1125	glycine betaine transport
AYJ57_RS04570	COG1174	glycine betaine transport
AYJ57_RS04575	COG0039	L-malate dehydrogenase activity
AYJ57_RS04580	COG0045	succinate-CoA ligase (ADP-forming) activity
AYJ57_RS04585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYJ57_RS04590	COG0567	Dehydrogenase, E1 component
AYJ57_RS04595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ57_RS04635	COG2884	Cell division ATP-binding protein ftsE
AYJ57_RS04645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_RS04650	COG1116	anion transmembrane transporter activity
AYJ57_RS04660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ57_RS04675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYJ57_RS04685	COG1196	nuclear chromosome segregation
AYJ57_RS04685	COG0741	lytic transglycosylase activity
AYJ57_RS04685	COG0739	heme binding
AYJ57_RS04695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AYJ57_RS04700	COG0602	queuosine metabolic process
AYJ57_RS04705	COG0720	synthase
AYJ57_RS04710	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AYJ57_RS04715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AYJ57_RS04720	COG0142	geranyltranstransferase activity
AYJ57_RS04725	COG1722	exodeoxyribonuclease VII activity
AYJ57_RS04730	COG0123	including yeast histone deacetylase and acetoin utilization protein
AYJ57_RS04735	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS04740	COG1846	Transcriptional regulator
AYJ57_RS04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYJ57_RS04770	COG3842	ATPase activity
AYJ57_RS04790	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS04800	COG1185	polyribonucleotide nucleotidyltransferase activity
AYJ57_RS04805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AYJ57_RS04825	COG2835	tetraacyldisaccharide 4'-kinase activity
AYJ57_RS04845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_RS04860	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AYJ57_RS04865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AYJ57_RS04870	COG4535	Mg2 and Co2 transporter CorC
AYJ57_RS04875	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AYJ57_RS04880	COG1702	phosphate starvation-inducible protein PhoH
AYJ57_RS04890	COG2885	chlorophyll binding
AYJ57_RS04895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AYJ57_RS04905	COG2871	sodium ion transport
AYJ57_RS04910	COG0735	belongs to the Fur family
AYJ57_RS04915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ57_RS04920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYJ57_RS04925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AYJ57_RS04935	COG1335	isochorismatase
AYJ57_RS04940	COG1566	PFAM secretion protein HlyD family protein
AYJ57_RS04960	COG1522	sequence-specific DNA binding
AYJ57_RS04980	COG0483	inositol monophosphate 1-phosphatase activity
AYJ57_RS04995	COG3119	arylsulfatase activity
AYJ57_RS05000	COG0583	DNA-binding transcription factor activity
AYJ57_RS05055	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AYJ57_RS05085	COG0187	DNA topoisomerase II activity
AYJ57_RS05110	COG3237	CsbD-like
AYJ57_RS05130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_RS05160	COG0556	nucleotide-excision repair
AYJ57_RS05180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AYJ57_RS05190	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AYJ57_RS05230	COG1294	oxidase, subunit
AYJ57_RS05235	COG1271	oxidase subunit
AYJ57_RS05240	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AYJ57_RS05245	COG4988	ABC transporter
AYJ57_RS05265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_RS05270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ57_RS05285	COG4598	ABC transporter
AYJ57_RS05290	COG0765	amino acid transport
AYJ57_RS05295	COG0765	amino acid transport
AYJ57_RS05300	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AYJ57_RS05305	COG0277	FAD linked oxidase domain protein
AYJ57_RS05310	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AYJ57_RS05320	COG2986	histidine ammonia-lyase
AYJ57_RS05325	COG1228	amidohydrolase
AYJ57_RS05335	COG0628	permease
AYJ57_RS05345	COG1295	ribonuclease BN
AYJ57_RS05355	COG1597	lipid kinase activity
AYJ57_RS05380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ57_RS05390	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYJ57_RS05400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYJ57_RS05420	COG1968	undecaprenyl-diphosphatase activity
AYJ57_RS05425	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AYJ57_RS05430	COG0799	negative regulation of ribosome biogenesis
AYJ57_RS05435	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_RS05460	COG2897	thiosulfate sulfurtransferase activity
AYJ57_RS05465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AYJ57_RS05475	COG3257	ureidoglycine aminohydrolase activity
AYJ57_RS05480	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AYJ57_RS05510	COG2951	lytic endotransglycosylase activity
AYJ57_RS05535	COG0235	Class ii aldolase
AYJ57_RS05540	COG2267	carboxylic ester hydrolase activity
AYJ57_RS05545	COG0251	oxidation-reduction process
AYJ57_RS05550	COG1335	isochorismatase
AYJ57_RS05555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_RS05570	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS05575	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS05585	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AYJ57_RS05605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_RS05635	COG4974	Belongs to the 'phage' integrase family
AYJ57_RS05640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYJ57_RS05650	COG0840	transmembrane signaling receptor activity
AYJ57_RS05655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AYJ57_RS05660	COG4143	(ABC) transporter
AYJ57_RS05670	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AYJ57_RS05695	COG2824	Alkylphosphonate utilization operon protein PhnA
AYJ57_RS05700	COG1183	phosphatidylcholine synthase activity
AYJ57_RS05715	COG0459	protein refolding
AYJ57_RS05720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AYJ57_RS05725	COG0697	spore germination
AYJ57_RS05745	COG0765	amino acid transport
AYJ57_RS05755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYJ57_RS05760	COG0756	dUTP diphosphatase activity
AYJ57_RS05765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYJ57_RS05780	COG0606	chelatase, subunit chli
AYJ57_RS05785	COG0657	acetylesterase activity
AYJ57_RS05795	COG0792	nuclease activity
AYJ57_RS05800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AYJ57_RS05810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AYJ57_RS05815	COG1278	Cold shock
AYJ57_RS05820	COG0513	Belongs to the DEAD box helicase family
AYJ57_RS05830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ57_RS05840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ57_RS05850	COG0180	Tryptophanyl-tRNA synthetase
AYJ57_RS05865	COG2255	four-way junction helicase activity
AYJ57_RS05870	COG0632	four-way junction helicase activity
AYJ57_RS05900	COG0662	Cupin 2, conserved barrel domain protein
AYJ57_RS05905	COG2391	methyltransferase activity
AYJ57_RS05910	COG0408	coproporphyrinogen oxidase activity
AYJ57_RS05920	COG2813	Specifically methylates the guanine in position
AYJ57_RS05925	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AYJ57_RS05935	COG1686	Belongs to the peptidase S11 family
AYJ57_RS05940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYJ57_RS05965	COG1047	Peptidyl-prolyl cis-trans
AYJ57_RS05980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYJ57_RS05995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYJ57_RS06000	COG0640	Transcriptional regulator
AYJ57_RS06005	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ57_RS06010	COG1132	(ABC) transporter
AYJ57_RS06025	COG0300	oxidoreductase activity
AYJ57_RS06030	COG3806	Anti-sigma factor
AYJ57_RS06035	COG1595	DNA-templated transcription, initiation
AYJ57_RS06050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ57_RS06060	COG2135	peptidase activity
AYJ57_RS06070	COG0590	tRNA wobble adenosine to inosine editing
AYJ57_RS06075	COG1187	pseudouridine synthase activity
AYJ57_RS06095	COG3853	Toxic anion resistance protein (TelA)
AYJ57_RS06125	COG1490	D-aminoacyl-tRNA deacylase activity
AYJ57_RS06145	COG4191	Histidine kinase
AYJ57_RS06160	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AYJ57_RS06165	COG0594	ribonuclease P activity
AYJ57_RS06170	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AYJ57_RS06175	COG0037	tRNA processing
AYJ57_RS06185	COG0706	membrane insertase activity
AYJ57_RS06195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AYJ57_RS06200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYJ57_RS06210	COG2062	phosphohistidine phosphatase, SixA
AYJ57_RS06215	COG1126	abc transporter atp-binding protein
AYJ57_RS06220	COG0765	amino acid transport
AYJ57_RS06225	COG4597	amino acid ABC transporter
AYJ57_RS06230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ57_RS06240	COG0546	phosphoglycolate phosphatase activity
AYJ57_RS06245	COG0564	pseudouridine synthase activity
AYJ57_RS06255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYJ57_RS06260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYJ57_RS06265	COG0560	Phosphoserine phosphatase
AYJ57_RS06280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AYJ57_RS06310	COG2197	response regulator
AYJ57_RS06330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ57_RS06340	COG2124	cytochrome p450
AYJ57_RS06345	COG2096	Adenosyltransferase
AYJ57_RS06355	COG0300	oxidoreductase activity
AYJ57_RS06365	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYJ57_RS06395	COG2192	nodulation
AYJ57_RS06405	COG1573	uracil-dna glycosylase
AYJ57_RS06415	COG3191	aminopeptidase activity
AYJ57_RS06435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_RS06445	COG2816	NAD+ diphosphatase activity
AYJ57_RS06450	COG3454	Phosphonate metabolism
AYJ57_RS06455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYJ57_RS06460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYJ57_RS06465	COG0039	L-malate dehydrogenase activity
AYJ57_RS06480	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AYJ57_RS06485	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS06490	COG2205	protein histidine kinase activity
AYJ57_RS06500	COG1660	Displays ATPase and GTPase activities
AYJ57_RS06510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYJ57_RS06520	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_RS06550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AYJ57_RS06555	COG1177	transmembrane transport
AYJ57_RS06565	COG3842	ATPase activity
AYJ57_RS06580	COG4638	Rieske (2fe-2S)
AYJ57_RS06595	COG0469	pyruvate kinase activity
AYJ57_RS06605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AYJ57_RS06610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYJ57_RS06615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AYJ57_RS06635	COG0495	leucyl-tRNA aminoacylation
AYJ57_RS06640	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS06655	COG0457	Tetratricopeptide repeat
AYJ57_RS06660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AYJ57_RS06665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ57_RS06670	COG0196	riboflavin kinase activity
AYJ57_RS06675	COG2983	Belongs to the UPF0260 family
AYJ57_RS06700	COG1674	ftsk spoiiie
AYJ57_RS06705	COG0436	Aminotransferase
AYJ57_RS06715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_RS06725	COG0557	exoribonuclease II activity
AYJ57_RS06730	COG2951	lytic endotransglycosylase activity
AYJ57_RS06740	COG1051	belongs to the nudix hydrolase family
AYJ57_RS06745	COG0793	Belongs to the peptidase S41A family
AYJ57_RS06755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AYJ57_RS06760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS06800	COG1872	DUF167
AYJ57_RS06805	COG0778	Nitroreductase
AYJ57_RS06820	COG0346	lactoylglutathione lyase activity
AYJ57_RS06855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AYJ57_RS06860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ57_RS06865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYJ57_RS06900	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYJ57_RS06905	COG4149	molybdate abc transporter
AYJ57_RS06910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ57_RS06945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AYJ57_RS06950	COG0285	dihydrofolate synthase activity
AYJ57_RS06955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYJ57_RS06960	COG2271	Major facilitator Superfamily
AYJ57_RS06965	COG0596	Alpha beta hydrolase
AYJ57_RS06965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ57_RS06965	COG2226	methyltransferase
AYJ57_RS06975	COG1671	Belongs to the UPF0178 family
AYJ57_RS06980	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AYJ57_RS06995	COG1131	(ABC) transporter
AYJ57_RS07030	COG0714	Associated with various cellular activities
AYJ57_RS07065	COG0277	FAD linked oxidase domain protein
AYJ57_RS07070	COG0277	FAD linked oxidase domain protein
AYJ57_RS07075	COG0247	lactate metabolic process
AYJ57_RS07080	COG3591	Belongs to the peptidase S1B family
AYJ57_RS07090	COG0071	Belongs to the small heat shock protein (HSP20) family
AYJ57_RS07100	COG3321	synthase
AYJ57_RS07100	COG0604	alcohol dehydrogenase
AYJ57_RS07105	COG0583	DNA-binding transcription factor activity
AYJ57_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
AYJ57_RS07140	COG3152	Membrane
AYJ57_RS07155	COG0437	4 iron, 4 sulfur cluster binding
AYJ57_RS07160	COG0243	molybdopterin cofactor binding
AYJ57_RS07175	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS07205	COG0673	inositol 2-dehydrogenase activity
AYJ57_RS07230	COG0489	protein tyrosine kinase activity
AYJ57_RS07270	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS07280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ57_RS07310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYJ57_RS07310	COG0517	IMP dehydrogenase activity
AYJ57_RS07315	COG1346	cytolysis
AYJ57_RS07320	COG1380	Effector of murein hydrolase LrgA
AYJ57_RS07345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AYJ57_RS07350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_RS07380	COG1115	amino acid carrier protein
AYJ57_RS07390	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AYJ57_RS07400	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AYJ57_RS07420	COG1999	signal sequence binding
AYJ57_RS07435	COG0802	atpase or kinase
AYJ57_RS07440	COG3178	'Phosphotransferase
AYJ57_RS07445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ57_RS07450	COG2887	Belongs to the helicase family. UvrD subfamily
AYJ57_RS07470	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AYJ57_RS07475	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AYJ57_RS07495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ57_RS07500	COG1301	dicarboxylic acid transport
AYJ57_RS07515	COG1040	competence protein
AYJ57_RS07550	COG3034	peptidoglycan biosynthetic process
AYJ57_RS07555	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYJ57_RS07560	COG1132	(ABC) transporter
AYJ57_RS07565	COG1132	(ABC) transporter
AYJ57_RS07580	COG0494	nUDIX hydrolase
AYJ57_RS07595	COG0745	RESPONSE REGULATOR receiver
AYJ57_RS07605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYJ57_RS07615	COG0137	argininosuccinate synthase activity
AYJ57_RS07635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ57_RS07640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_RS07645	COG0280	phosphate acetyltransferase
AYJ57_RS07645	COG0281	malic enzyme
AYJ57_RS07650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AYJ57_RS07655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AYJ57_RS07660	COG1420	regulation of RNA biosynthetic process
AYJ57_RS07665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AYJ57_RS07670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AYJ57_RS07675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYJ57_RS07690	COG0357	Ribosomal RNA small subunit methyltransferase G
AYJ57_RS07695	COG0445	tRNA wobble uridine modification
AYJ57_RS07700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AYJ57_RS07705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYJ57_RS07710	COG0424	maF-like protein
AYJ57_RS07715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYJ57_RS07720	COG0237	dephospho-CoA kinase activity
AYJ57_RS07725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYJ57_RS07730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AYJ57_RS07735	COG3030	protein affecting phage T7 exclusion by the F plasmid
AYJ57_RS07755	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AYJ57_RS07760	COG3474	cytochrome
AYJ57_RS07765	COG1596	polysaccharide export
AYJ57_RS07770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYJ57_RS07780	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ57_RS07815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AYJ57_RS07820	COG2226	methyltransferase
AYJ57_RS07825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AYJ57_RS07840	COG0268	Binds directly to 16S ribosomal RNA
AYJ57_RS07845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AYJ57_RS07855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AYJ57_RS07915	COG0601	transmembrane transport
AYJ57_RS07920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_RS07925	COG4172	Belongs to the ABC transporter superfamily
AYJ57_RS07930	COG1309	transcriptional regulator
AYJ57_RS07935	COG0604	alcohol dehydrogenase
AYJ57_RS07945	COG0697	spore germination
AYJ57_RS07950	COG0473	3-isopropylmalate dehydrogenase activity
AYJ57_RS07965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYJ57_RS07975	COG0066	3-isopropylmalate dehydratase activity
AYJ57_RS07985	COG3264	Mechanosensitive ion channel
AYJ57_RS07985	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AYJ57_RS07990	COG0183	Belongs to the thiolase family
AYJ57_RS08000	COG5002	protein histidine kinase activity
AYJ57_RS08000	COG2205	protein histidine kinase activity
AYJ57_RS08000	COG0784	Response regulator, receiver
AYJ57_RS08005	COG3022	response to hydroperoxide
AYJ57_RS08010	COG0514	ATP-dependent DNA helicase (RecQ)
AYJ57_RS08020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AYJ57_RS08030	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AYJ57_RS08055	COG0019	diaminopimelate decarboxylase activity
AYJ57_RS08075	COG0165	Argininosuccinate lyase
AYJ57_RS08080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ57_RS08095	COG0287	Prephenate dehydrogenase
AYJ57_RS08100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYJ57_RS08105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AYJ57_RS08110	COG1335	isochorismatase
AYJ57_RS08115	COG1054	Belongs to the UPF0176 family
AYJ57_RS08120	COG1338	Plays a role in the flagellum-specific transport system
AYJ57_RS08125	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ57_RS08135	COG1766	The M ring may be actively involved in energy transduction
AYJ57_RS08155	COG3118	belongs to the thioredoxin family
AYJ57_RS08160	COG1376	ErfK ybiS ycfS ynhG family protein
AYJ57_RS08175	COG4181	ATPase activity
AYJ57_RS08185	COG0483	inositol monophosphate 1-phosphatase activity
AYJ57_RS08190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AYJ57_RS08190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AYJ57_RS08195	COG0509	glycine decarboxylation via glycine cleavage system
AYJ57_RS08200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_RS08205	COG1959	2 iron, 2 sulfur cluster binding
AYJ57_RS08220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ57_RS08245	COG3128	pkhd-type hydroxylase
AYJ57_RS08270	COG3046	protein related to deoxyribodipyrimidine photolyase
AYJ57_RS08290	COG3842	ATPase activity
AYJ57_RS08300	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_RS08315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYJ57_RS08315	COG1648	precorrin-2 dehydrogenase activity
AYJ57_RS08320	COG0243	molybdopterin cofactor binding
AYJ57_RS08325	COG2146	nitrite reductase [NAD(P)H] activity
AYJ57_RS08330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ57_RS08335	COG1116	anion transmembrane transporter activity
AYJ57_RS08340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_RS08345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ57_RS08350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ57_RS08350	COG1116	anion transmembrane transporter activity
AYJ57_RS08355	COG3707	response regulator
AYJ57_RS08375	COG3842	ATPase activity
AYJ57_RS08380	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ57_RS08385	COG1177	transmembrane transport
AYJ57_RS08390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_RS08395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYJ57_RS08400	COG0004	ammonium transporteR
AYJ57_RS08405	COG0347	Belongs to the P(II) protein family
AYJ57_RS08410	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYJ57_RS08415	COG0284	orotidine-5'-phosphate decarboxylase activity
AYJ57_RS08445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYJ57_RS08465	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYJ57_RS08485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ57_RS08485	COG2169	Transcriptional regulator
AYJ57_RS08490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYJ57_RS08495	COG2186	Transcriptional regulator
AYJ57_RS08500	COG0314	molybdopterin synthase activity
AYJ57_RS08510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYJ57_RS08515	COG1381	Involved in DNA repair and RecF pathway recombination
AYJ57_RS08530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AYJ57_RS08535	COG0697	spore germination
AYJ57_RS08540	COG0571	ribonuclease III activity
AYJ57_RS08545	COG0681	Belongs to the peptidase S26 family
AYJ57_RS08550	COG0736	holo-[acyl-carrier-protein] synthase activity
AYJ57_RS08555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYJ57_RS08565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYJ57_RS08575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYJ57_RS08585	COG1238	metal cluster binding
AYJ57_RS08590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AYJ57_RS08610	COG0328	RNA-DNA hybrid ribonuclease activity
AYJ57_RS08615	COG2860	membrane
AYJ57_RS08620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYJ57_RS08625	COG0242	peptide deformylase activity
AYJ57_RS08630	COG0242	peptide deformylase activity
AYJ57_RS08635	COG0242	peptide deformylase activity
AYJ57_RS08640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYJ57_RS08650	COG0435	Glutathione S-transferase
AYJ57_RS08670	COG0154	amidase activity
AYJ57_RS08675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ57_RS08685	COG4221	oxidoreductase activity
AYJ57_RS08690	COG1024	Enoyl-CoA hydratase
AYJ57_RS08695	COG0840	transmembrane signaling receptor activity
AYJ57_RS08705	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AYJ57_RS08725	COG2171	N-acyltransferase activity
AYJ57_RS08750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYJ57_RS08775	COG0288	reversible hydration of carbon dioxide
AYJ57_RS08785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AYJ57_RS08790	COG0791	NLP P60 protein
AYJ57_RS08810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AYJ57_RS08815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_RS08820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYJ57_RS08825	COG0659	secondary active sulfate transmembrane transporter activity
AYJ57_RS08835	COG0254	rRNA binding
AYJ57_RS08840	COG0335	large ribosomal subunit rRNA binding
AYJ57_RS08845	COG0336	Belongs to the RNA methyltransferase TrmD family
AYJ57_RS08855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYJ57_RS08865	COG0228	four-way junction DNA binding
AYJ57_RS08895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYJ57_RS08920	COG0356	it plays a direct role in the translocation of protons across the membrane
AYJ57_RS08925	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AYJ57_RS08930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYJ57_RS08935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYJ57_RS08940	COG0489	protein tyrosine kinase activity
AYJ57_RS08940	COG2151	metal-sulfur cluster biosynthetic enzyme
AYJ57_RS08965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AYJ57_RS08970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AYJ57_RS08975	COG0747	negative chemotaxis
AYJ57_RS08980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ57_RS08990	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AYJ57_RS09015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ57_RS09030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AYJ57_RS09035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AYJ57_RS09040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AYJ57_RS09045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AYJ57_RS09070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AYJ57_RS09085	COG0540	Belongs to the ATCase OTCase family
AYJ57_RS09090	COG0742	ribosomal rna small subunit methyltransferase
AYJ57_RS09100	COG0678	peroxiredoxin activity
AYJ57_RS09105	COG2154	pterin-4-alpha-carbinolamine dehydratase
AYJ57_RS09125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ57_RS09130	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
AYJ57_RS09135	COG2853	Lipoprotein
AYJ57_RS09155	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AYJ57_RS09160	COG0069	glutamate synthase activity
AYJ57_RS09165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AYJ57_RS09170	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AYJ57_RS09205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AYJ57_RS09245	COG0250	Participates in transcription elongation, termination and antitermination
AYJ57_RS09250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AYJ57_RS09255	COG0081	regulation of translation
AYJ57_RS09260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AYJ57_RS09265	COG0222	ribosome binding
AYJ57_RS09270	COG0085	RNA polymerase activity
AYJ57_RS09275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AYJ57_RS09290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AYJ57_RS09295	COG0049	tRNA binding
AYJ57_RS09300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AYJ57_RS09305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ57_RS09310	COG0051	transcription antitermination factor activity, RNA binding
AYJ57_RS09315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AYJ57_RS09320	COG0088	Forms part of the polypeptide exit tunnel
AYJ57_RS09325	COG0089	rRNA binding
AYJ57_RS09330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AYJ57_RS09335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AYJ57_RS09340	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AYJ57_RS09345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AYJ57_RS09350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AYJ57_RS09360	COG0255	Belongs to the universal ribosomal protein uL29 family
AYJ57_RS09365	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AYJ57_RS09370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AYJ57_RS09375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AYJ57_RS09380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AYJ57_RS09385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AYJ57_RS09390	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AYJ57_RS09395	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AYJ57_RS09400	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AYJ57_RS09405	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AYJ57_RS09410	COG1841	ribosomal large subunit assembly
AYJ57_RS09415	COG0200	Binds to the 23S rRNA
AYJ57_RS09420	COG0201	protein transport
AYJ57_RS09425	COG0563	adenylate kinase activity
AYJ57_RS09435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AYJ57_RS09440	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYJ57_RS09445	COG0202	RNA polymerase activity
AYJ57_RS09460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYJ57_RS09485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYJ57_RS09485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYJ57_RS09490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_RS09495	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYJ57_RS09500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ57_RS09500	COG2169	Transcriptional regulator
AYJ57_RS09505	COG2885	chlorophyll binding
AYJ57_RS09515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYJ57_RS09525	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYJ57_RS09530	COG1137	ATPase activity
AYJ57_RS09535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AYJ57_RS09540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYJ57_RS09565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYJ57_RS09570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYJ57_RS09580	COG1218	3'(2'),5'-bisphosphate nucleotidase
AYJ57_RS09600	COG0443	Heat shock 70 kDa protein
AYJ57_RS09605	COG0484	heat shock protein binding
AYJ57_RS09610	COG2003	Belongs to the UPF0758 family
AYJ57_RS09625	COG0653	protein targeting
AYJ57_RS09630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ57_RS09635	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYJ57_RS09640	COG0494	nUDIX hydrolase
AYJ57_RS09645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AYJ57_RS09660	COG0779	Required for maturation of 30S ribosomal subunits
AYJ57_RS09685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AYJ57_RS09690	COG0142	geranyltranstransferase activity
AYJ57_RS09700	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AYJ57_RS09710	COG0346	lactoylglutathione lyase activity
AYJ57_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS09730	COG2200	EAL domain
AYJ57_RS09735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AYJ57_RS09740	COG1309	transcriptional regulator
AYJ57_RS09765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_RS09770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ57_RS09790	COG1609	Transcriptional regulator
AYJ57_RS09805	COG0583	DNA-binding transcription factor activity
AYJ57_RS09810	COG1136	(ABC) transporter
AYJ57_RS09810	COG0577	efflux transmembrane transporter activity
AYJ57_RS09830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AYJ57_RS09840	COG1496	oxidoreductase activity
AYJ57_RS09850	COG1522	sequence-specific DNA binding
AYJ57_RS09855	COG0492	ferredoxin-NADP+ reductase activity
AYJ57_RS09865	COG2046	Belongs to the sulfate adenylyltransferase family
AYJ57_RS09865	COG0529	Catalyzes the synthesis of activated sulfate
AYJ57_RS09875	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AYJ57_RS09900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ57_RS09910	COG1435	thymidine kinase activity
AYJ57_RS09925	COG0471	metal ion transport
AYJ57_RS09925	COG3273	potassium ion transport
AYJ57_RS09935	COG0842	Transport permease protein
AYJ57_RS09940	COG1183	phosphatidylcholine synthase activity
AYJ57_RS09945	COG2808	Putative FMN-binding domain
AYJ57_RS09950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AYJ57_RS09955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AYJ57_RS09975	COG2244	polysaccharide biosynthetic process
AYJ57_RS10020	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS10040	COG1960	acyl-CoA dehydrogenase activity
AYJ57_RS10055	COG3320	Male sterility
AYJ57_RS10055	COG1022	Amp-dependent synthetase and ligase
AYJ57_RS10060	COG1024	Enoyl-CoA hydratase
AYJ57_RS10080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_RS10105	COG1335	isochorismatase
AYJ57_RS10110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ57_RS10115	COG0154	amidase activity
AYJ57_RS10120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYJ57_RS10125	COG2186	Transcriptional regulator
AYJ57_RS10140	COG0154	amidase activity
AYJ57_RS10145	COG0778	Nitroreductase
AYJ57_RS10150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ57_RS10150	COG0072	phenylalanine-tRNA ligase activity
AYJ57_RS10160	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYJ57_RS10180	COG0400	carboxylic ester hydrolase activity
AYJ57_RS10195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_RS10215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYJ57_RS10225	COG1278	Cold shock
AYJ57_RS10235	COG0488	(ABC) transporter
AYJ57_RS10240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AYJ57_RS10255	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AYJ57_RS10275	COG2894	cell division
AYJ57_RS10285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AYJ57_RS10310	COG1832	CoA-binding protein
AYJ57_RS10315	COG0140	phosphoribosyl-ATP diphosphatase activity
AYJ57_RS10320	COG0107	imidazoleglycerol-phosphate synthase activity
AYJ57_RS10325	COG0737	Belongs to the 5'-nucleotidase family
AYJ57_RS10330	COG1309	transcriptional regulator
AYJ57_RS10350	COG1393	Belongs to the ArsC family
AYJ57_RS10355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AYJ57_RS10355	COG0116	Belongs to the methyltransferase superfamily
AYJ57_RS10360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AYJ57_RS10365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYJ57_RS10370	COG0131	Imidazoleglycerol-phosphate dehydratase
AYJ57_RS10395	COG0210	DNA helicase
AYJ57_RS10405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AYJ57_RS10425	COG0583	DNA-binding transcription factor activity
AYJ57_RS10430	COG1960	acyl-CoA dehydrogenase activity
AYJ57_RS10435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYJ57_RS10475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYJ57_RS10480	COG0527	aspartate kinase activity
AYJ57_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS10505	COG1519	Transferase
AYJ57_RS10515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYJ57_RS10525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYJ57_RS10525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYJ57_RS10530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AYJ57_RS10535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AYJ57_RS10580	COG0564	pseudouridine synthase activity
AYJ57_RS10585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AYJ57_RS10605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYJ57_RS10610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ57_RS10615	COG0174	glutamine synthetase
AYJ57_RS10620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ57_RS10620	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ57_RS10625	COG0174	glutamine synthetase
AYJ57_RS10630	COG4160	amino acid transport
AYJ57_RS10635	COG4215	(ABC) transporter
AYJ57_RS10660	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYJ57_RS10670	COG0504	CTP synthase activity
AYJ57_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS10700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYJ57_RS10700	COG0616	signal peptide processing
AYJ57_RS10715	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS10720	COG0322	excinuclease ABC activity
AYJ57_RS10730	COG0012	GTP binding
AYJ57_RS10735	COG0534	Mate efflux family protein
AYJ57_RS10755	COG2326	polyphosphate kinase activity
AYJ57_RS10765	COG0159	tryptophan synthase activity
AYJ57_RS10770	COG2084	Dehydrogenase
AYJ57_RS10775	COG3395	kinase activity
AYJ57_RS10780	COG0235	Class ii aldolase
AYJ57_RS10785	COG3622	Belongs to the hyi family
AYJ57_RS10790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ57_RS10800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ57_RS10810	COG0277	FAD linked oxidase domain protein
AYJ57_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS10835	COG1609	Transcriptional regulator
AYJ57_RS10850	COG0129	dihydroxy-acid dehydratase activity
AYJ57_RS10855	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS10865	COG0697	spore germination
AYJ57_RS10870	COG2084	Dehydrogenase
AYJ57_RS10875	COG2721	sulfolactate sulfo-lyase activity
AYJ57_RS10895	COG1802	Transcriptional regulator
AYJ57_RS10930	COG0583	DNA-binding transcription factor activity
AYJ57_RS10935	COG0247	lactate metabolic process
AYJ57_RS10935	COG0277	FAD linked oxidase domain protein
AYJ57_RS10940	COG1349	DNA-binding transcription factor activity
AYJ57_RS10955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYJ57_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS10970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ57_RS10975	COG0583	DNA-binding transcription factor activity
AYJ57_RS10985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS10995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_RS11015	COG0601	transmembrane transport
AYJ57_RS11020	COG0747	negative chemotaxis
AYJ57_RS11045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_RS11055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS11095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AYJ57_RS11100	COG4608	Belongs to the ABC transporter superfamily
AYJ57_RS11105	COG0444	Belongs to the ABC transporter superfamily
AYJ57_RS11110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_RS11115	COG0601	transmembrane transport
AYJ57_RS11195	COG0824	Thioesterase
AYJ57_RS11210	COG1960	acyl-CoA dehydrogenase activity
AYJ57_RS11215	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYJ57_RS11215	COG1024	Enoyl-CoA hydratase
AYJ57_RS11220	COG0183	Belongs to the thiolase family
AYJ57_RS11230	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ57_RS11240	COG1607	acyl-coa hydrolase
AYJ57_RS11250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_RS11255	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AYJ57_RS11260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS11270	COG2721	sulfolactate sulfo-lyase activity
AYJ57_RS11275	COG2721	sulfolactate sulfo-lyase activity
AYJ57_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS11310	COG1692	metallophosphoesterase
AYJ57_RS11320	COG0471	metal ion transport
AYJ57_RS11320	COG3273	potassium ion transport
AYJ57_RS11325	COG0217	transcriptional regulatory protein
AYJ57_RS11350	COG2267	carboxylic ester hydrolase activity
AYJ57_RS11360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYJ57_RS11370	COG0512	Glutamine amidotransferase of anthranilate synthase
AYJ57_RS11370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYJ57_RS11380	COG0670	Belongs to the BI1 family
AYJ57_RS11390	COG0583	DNA-binding transcription factor activity
AYJ57_RS11400	COG1396	sequence-specific DNA binding
AYJ57_RS11405	COG0483	inositol monophosphate 1-phosphatase activity
AYJ57_RS11425	COG0402	S-adenosylhomocysteine deaminase activity
AYJ57_RS11430	COG2239	Acts as a magnesium transporter
AYJ57_RS11435	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYJ57_RS11440	COG0151	Belongs to the GarS family
AYJ57_RS11450	COG1570	exodeoxyribonuclease VII activity
AYJ57_RS11460	COG0741	lytic transglycosylase activity
AYJ57_RS11465	COG0552	protein localization to endoplasmic reticulum
AYJ57_RS11470	COG1285	pathogenesis
AYJ57_RS11475	COG2917	probably involved in intracellular septation
AYJ57_RS11480	COG0477	Major facilitator Superfamily
AYJ57_RS11490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AYJ57_RS11510	COG0084	hydrolase, TatD family'
AYJ57_RS11520	COG2001	Belongs to the MraZ family
AYJ57_RS11525	COG0275	rRNA processing
AYJ57_RS11540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYJ57_RS11550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYJ57_RS11555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AYJ57_RS11565	COG2081	HI0933 family
AYJ57_RS11575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AYJ57_RS11580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYJ57_RS11595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AYJ57_RS11600	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYJ57_RS11605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYJ57_RS11610	COG0849	cell division
AYJ57_RS11615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYJ57_RS11625	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ57_RS11635	COG0525	valine-tRNA ligase activity
AYJ57_RS11650	COG0489	protein tyrosine kinase activity
AYJ57_RS11660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYJ57_RS11665	COG1686	Belongs to the peptidase S11 family
AYJ57_RS11760	COG2205	protein histidine kinase activity
AYJ57_RS11795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AYJ57_RS11800	COG3596	GTP binding
AYJ57_RS11815	COG0798	PFAM Bile acid sodium symporter
AYJ57_RS11820	COG0431	NADPH-dependent FMN reductase
AYJ57_RS11830	COG0583	DNA-binding transcription factor activity
AYJ57_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS11890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYJ57_RS11895	COG1845	cytochrome c oxidase, subunit III
AYJ57_RS11900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYJ57_RS11905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYJ57_RS11920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYJ57_RS11925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AYJ57_RS11930	COG4221	oxidoreductase activity
AYJ57_RS11940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYJ57_RS11975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYJ57_RS11980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYJ57_RS11990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AYJ57_RS11995	COG0418	dihydroorotase activity
AYJ57_RS12025	COG0156	8-amino-7-oxononanoate synthase activity
AYJ57_RS12035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AYJ57_RS12055	COG0436	Aminotransferase
AYJ57_RS12060	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYJ57_RS12065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AYJ57_RS12070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ57_RS12075	COG0601	transmembrane transport
AYJ57_RS12085	COG4172	Belongs to the ABC transporter superfamily
AYJ57_RS12090	COG0850	regulation of cytokinetic process
AYJ57_RS12095	COG2894	cell division
AYJ57_RS12100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AYJ57_RS12105	COG0443	Heat shock 70 kDa protein
AYJ57_RS12120	COG1473	amidohydrolase
AYJ57_RS12130	COG0668	transmembrane transport
AYJ57_RS12140	COG4251	negative regulation of phosphorylation
AYJ57_RS12150	COG0587	DNA-directed DNA polymerase activity
AYJ57_RS12165	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AYJ57_RS12170	COG1652	LysM domain
AYJ57_RS12195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AYJ57_RS12205	COG0800	Aldolase
AYJ57_RS12210	COG0129	dihydroxy-acid dehydratase activity
AYJ57_RS12225	COG1320	monovalent cation:proton antiporter activity
AYJ57_RS12230	COG2212	antiporter activity
AYJ57_RS12235	COG1863	multisubunit Na H antiporter MnhE subunit
AYJ57_RS12240	COG0651	ATP synthesis coupled electron transport
AYJ57_RS12245	COG1006	Multisubunit Na H antiporter MnhC subunit
AYJ57_RS12250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYJ57_RS12250	COG2111	Na H antiporter
AYJ57_RS12255	COG3842	ATPase activity
AYJ57_RS12305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYJ57_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS12330	COG4335	DNA alkylation repair
AYJ57_RS12340	COG0343	queuine tRNA-ribosyltransferase activity
AYJ57_RS12355	COG1902	pentaerythritol trinitrate reductase activity
AYJ57_RS12400	COG3220	belongs to the UPF0276 family
AYJ57_RS12415	COG0501	Belongs to the peptidase M48B family
AYJ57_RS12420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AYJ57_RS12425	COG5425	PFAM Usg family protein
AYJ57_RS12445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYJ57_RS12460	COG0586	Pfam SNARE associated Golgi protein
AYJ57_RS12465	COG2610	gluconate transmembrane transporter activity
AYJ57_RS12470	COG1215	transferase activity, transferring glycosyl groups
AYJ57_RS12475	COG3769	mannosylglycerate metabolic process
AYJ57_RS12485	COG0583	DNA-binding transcription factor activity
AYJ57_RS12490	COG1278	Cold shock
AYJ57_RS12495	COG1393	Belongs to the ArsC family
AYJ57_RS12500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AYJ57_RS12550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ57_RS12570	COG1793	dna ligase
AYJ57_RS12570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AYJ57_RS12600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYJ57_RS12605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYJ57_RS12610	COG1329	Transcriptional regulator
AYJ57_RS12615	COG1252	NADH dehydrogenase
AYJ57_RS12630	COG1469	GTP cyclohydrolase I activity
AYJ57_RS12640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ57_RS12645	COG0277	FAD linked oxidase domain protein
AYJ57_RS12655	COG1764	response to oxidative stress
AYJ57_RS12660	COG1846	Transcriptional regulator
AYJ57_RS12670	COG0006	proline dipeptidase activity
AYJ57_RS12705	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AYJ57_RS12710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ57_RS12730	COG3135	benzoate transporter
AYJ57_RS12750	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AYJ57_RS12760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ57_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ57_RS12785	COG0308	aminopeptidase N
AYJ57_RS12825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ57_RS12840	COG2995	paraquat-inducible protein a
AYJ57_RS12845	COG3008	intermembrane lipid transfer
AYJ57_RS12845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYJ57_RS12865	COG0488	(ABC) transporter
AYJ57_RS12875	COG2176	DNA-directed DNA polymerase activity
AYJ57_RS12875	COG5002	protein histidine kinase activity
AYJ57_RS12890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYJ57_RS12905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ57_RS12930	COG0784	Response regulator, receiver
AYJ57_RS12950	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AYJ57_RS12965	COG1160	GTP binding
AYJ57_RS12985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AYJ57_RS12990	COG3591	Belongs to the peptidase S1B family
AYJ57_RS13005	COG1862	Preprotein translocase
AYJ57_RS13010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ57_RS13015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ57_RS13020	COG3737	Protein of unknown function (DUF498/DUF598)
AYJ57_RS13025	COG4133	protoheme IX ABC transporter activity
AYJ57_RS13030	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYJ57_RS13035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYJ57_RS13045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ57_RS13050	COG1268	BioY protein
AYJ57_RS13090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYJ57_RS13090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYJ57_RS13115	COG4176	ABC-type proline glycine betaine transport system permease component
AYJ57_RS13135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ57_RS13140	COG0463	Glycosyl transferase, family 2
AYJ57_RS13190	COG4106	trans-aconitate 2-methyltransferase activity
AYJ57_RS13200	COG0463	Glycosyl transferase, family 2
AYJ57_RS13210	COG0492	ferredoxin-NADP+ reductase activity
AYJ57_RS13270	COG2226	methyltransferase
AYJ57_RS13275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ57_RS13300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AYJ57_RS13350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYJ57_RS13365	COG0248	Ppx GppA phosphatase
AYJ57_RS13370	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AYJ57_RS13455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYJ57_RS13460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYJ57_RS13465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYJ57_RS13470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AYJ57_RS13475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ57_RS13480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AYJ57_RS13495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AYJ57_RS13505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYJ57_RS13510	COG3577	Aspartyl protease
AYJ57_RS13515	COG2095	MarC family integral membrane protein
AYJ57_RS13520	COG0488	(ABC) transporter
AYJ57_RS13525	COG0105	UTP biosynthetic process
AYJ57_RS13575	COG3842	ATPase activity
AYJ57_RS13580	COG4695	Portal protein
AYJ57_RS13660	COG2814	Major facilitator Superfamily
AYJ57_RS13665	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ57_RS13670	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ57_RS13670	COG0022	dehydrogenase e1 component
AYJ57_RS13675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AYJ57_RS13680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AYJ57_RS13685	COG0126	phosphoglycerate kinase activity
AYJ57_RS13715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ57_RS13735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AYJ57_RS13745	COG0316	Belongs to the HesB IscA family
AYJ57_RS13750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AYJ57_RS13760	COG0018	arginyl-trna synthetase
AYJ57_RS13770	COG1472	Belongs to the glycosyl hydrolase 3 family
AYJ57_RS13775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AYJ57_RS13780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AYJ57_RS13795	COG0717	Belongs to the dCTP deaminase family
AYJ57_RS13810	COG0776	regulation of translation
AYJ57_RS13815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYJ57_RS13820	COG0416	fatty acid biosynthetic process
AYJ57_RS13825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AYJ57_RS14280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_RS14280	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ57_RS14350	COG0415	Belongs to the DNA photolyase family
AYJ57_RS14415	COG1957	nucleoside hydrolase
AYJ57_RS14535	COG0033	Phosphoglucomutase
AYJ57_RS15035	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AYJ57_RS15100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ57_RS15490	COG3844	kynureninase activity
AYJ57_RS15510	COG5265	(ABC) transporter
AYJ57_RS15680	COG2010	Cytochrome c
AYJ57_RS15765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYJ57_RS15780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AYJ57_RS16065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ57_RS16065	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ57_RS16235	COG1612	heme a metabolic process
AYJ57_RS16305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ57_RS16345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AYJ57_RS16495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ57_RS16790	COG1840	ABC-type Fe3 transport system, periplasmic component
AYJ57_RS17145	COG4191	Histidine kinase
AYJ57_RS17185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYJ57_RS17465	COG1530	ribonuclease E activity
AYJ57_RS17505	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYJ57_RS17520	COG1192	Involved in chromosome partitioning
AYJ57_RS17785	COG0348	domain, Protein
AYJ57_RS17840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ57_RS17975	COG2030	dehydratase
AYJ57_RS18240	COG1185	polyribonucleotide nucleotidyltransferase activity
AYJ57_RS18490	COG0187	DNA topoisomerase II activity
AYJ57_RS18645	COG1271	oxidase subunit
AYJ57_RS18695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ57_RS18765	COG2986	histidine ammonia-lyase
AYJ57_RS18770	COG1228	amidohydrolase
AYJ57_RS19035	COG0840	transmembrane signaling receptor activity
AYJ57_RS19425	COG1187	pseudouridine synthase activity
AYJ57_RS19870	COG3842	ATPase activity
AYJ57_RS19955	COG0457	Tetratricopeptide repeat
AYJ57_RS20045	COG0793	Belongs to the peptidase S41A family
AYJ57_RS20125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AYJ57_RS20140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYJ57_RS20145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AYJ57_RS20555	COG4656	Part of a membrane complex involved in electron transport
AYJ57_RS20645	COG1104	cysteine desulfurase activity
AYJ57_RS20800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYJ57_RS21075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYJ57_RS21325	COG2130	NADP-dependent
AYJ57_RS21450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_RS21455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_RS21760	COG1138	Cytochrome C-type biogenesis protein
AYJ57_RS21910	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AYJ57_RS22180	COG3604	Transcriptional regulator
AYJ57_RS22240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ57_RS22480	COG0033	Phosphoglucomutase
AYJ57_RS22560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYJ57_RS22620	COG0438	transferase activity, transferring glycosyl groups
AYJ57_RS22655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYJ57_RS23480	COG3264	Mechanosensitive ion channel
AYJ57_RS23480	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AYJ57_RS23760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYJ57_RS23955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ57_RS24125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ57_RS24475	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AYJ57_RS24630	COG4235	cytochrome complex assembly
AYJ57_RS24765	COG0363	glucosamine-6-phosphate deaminase activity
AYJ57_RS24890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AYJ57_RS24900	COG0058	SHG alpha-glucan phosphorylase activity
AYJ57_RS25175	COG2313	pseudouridylate synthase activity
AYJ57_RS25420	COG1104	cysteine desulfurase activity