locus-tag	class	description
ACZ76_RS00015	COG3077	Addiction module antitoxin, RelB DinJ family
ACZ76_RS00020	COG2026	Addiction module toxin, RelE StbE family
ACZ76_RS00045	COG1475	DNA binding
ACZ76_RS00060	COG3772	lysozyme
ACZ76_RS00140	COG1396	sequence-specific DNA binding
ACZ76_RS00175	COG0582	viral genome integration into host DNA
ACZ76_RS00185	COG1276	copper resistance
ACZ76_RS00190	COG2372	response to copper ion
ACZ76_RS00195	COG1528	Iron-storage protein
ACZ76_RS00210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACZ76_RS00215	COG1770	oligopeptidase
ACZ76_RS00225	COG3097	Belongs to the UPF0267 family
ACZ76_RS00230	COG3141	response to X-ray
ACZ76_RS00235	COG0513	Belongs to the DEAD box helicase family
ACZ76_RS00240	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACZ76_RS00245	COG3140	Belongs to the UPF0181 family
ACZ76_RS00255	COG0494	nUDIX hydrolase
ACZ76_RS00260	COG1760	l-serine dehydratase
ACZ76_RS00265	COG1253	flavin adenine dinucleotide binding
ACZ76_RS00270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS00270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS00275	COG3715	PTS system
ACZ76_RS00280	COG3716	PTS system mannose fructose sorbose family IID component
ACZ76_RS00285	COG4811	Protein of unknown function (DUF986)
ACZ76_RS00290	COG1971	Probably functions as a manganese efflux pump
ACZ76_RS00300	COG3447	MASE1 domain protein
ACZ76_RS00300	COG5001	Diguanylate cyclase
ACZ76_RS00300	COG5002	protein histidine kinase activity
ACZ76_RS00310	COG2226	methyltransferase
ACZ76_RS00315	COG0768	penicillin binding
ACZ76_RS00320	COG1496	oxidoreductase activity
ACZ76_RS00335	COG1113	amino acid transport
ACZ76_RS00370	COG2207	Transcriptional regulator
ACZ76_RS00390	COG1132	(ABC) transporter
ACZ76_RS00400	COG2203	Gaf domain
ACZ76_RS00400	COG4251	negative regulation of phosphorylation
ACZ76_RS00400	COG3706	GGDEF domain
ACZ76_RS00400	COG5001	Diguanylate cyclase
ACZ76_RS00415	COG3755	Protein conserved in bacteria
ACZ76_RS00430	COG1733	regulation of RNA biosynthetic process
ACZ76_RS00435	COG0702	epimerase
ACZ76_RS00440	COG2873	o-acetylhomoserine
ACZ76_RS00445	COG0840	transmembrane signaling receptor activity
ACZ76_RS00465	COG4974	Belongs to the 'phage' integrase family
ACZ76_RS00545	COG0210	DNA helicase
ACZ76_RS00560	COG4695	Portal protein
ACZ76_RS00650	COG5301	cellulose 1,4-beta-cellobiosidase activity
ACZ76_RS00715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACZ76_RS00720	COG0322	excinuclease ABC activity
ACZ76_RS00725	COG2197	response regulator
ACZ76_RS00735	COG3136	membrane protein required for alginate biosynthesis
ACZ76_RS00745	COG0840	transmembrane signaling receptor activity
ACZ76_RS00750	COG0366	Alpha amylase catalytic
ACZ76_RS00765	COG2226	methyltransferase
ACZ76_RS00775	COG1113	amino acid transport
ACZ76_RS00780	COG1309	transcriptional regulator
ACZ76_RS00785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACZ76_RS00790	COG1335	isochorismatase
ACZ76_RS00795	COG0251	oxidation-reduction process
ACZ76_RS00800	COG2267	carboxylic ester hydrolase activity
ACZ76_RS00805	COG0778	Nitroreductase
ACZ76_RS00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACZ76_RS00815	COG2233	PERMEase
ACZ76_RS00835	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ACZ76_RS00860	COG0672	)-iron permease
ACZ76_RS00865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ76_RS00870	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACZ76_RS00870	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACZ76_RS00870	COG0506	proline dehydrogenase activity
ACZ76_RS00885	COG1126	abc transporter atp-binding protein
ACZ76_RS00890	COG0765	amino acid transport
ACZ76_RS00895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS00900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACZ76_RS00910	COG1191	sigma factor activity
ACZ76_RS00945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACZ76_RS00950	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACZ76_RS00955	COG1677	Flagellar hook-basal body complex protein FliE
ACZ76_RS00970	COG1317	bacterial-type flagellum organization
ACZ76_RS00985	COG3144	bacterial-type flagellum assembly
ACZ76_RS01010	COG1338	Plays a role in the flagellum-specific transport system
ACZ76_RS01030	COG1256	bacterial-type flagellum assembly
ACZ76_RS01065	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACZ76_RS01070	COG1558	bacterial-type flagellum-dependent cell motility
ACZ76_RS01075	COG1815	bacterial-type flagellum-dependent cell motility
ACZ76_RS01085	COG2747	anti-sigma28 factor FlgM
ACZ76_RS01090	COG3418	PFAM FlgN family protein
ACZ76_RS01100	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACZ76_RS01105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACZ76_RS01110	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ACZ76_RS01115	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS01125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACZ76_RS01130	COG0840	transmembrane signaling receptor activity
ACZ76_RS01135	COG0840	transmembrane signaling receptor activity
ACZ76_RS01140	COG0835	chemotaxis
ACZ76_RS01145	COG2198	Histidine kinase
ACZ76_RS01145	COG0643	Histidine kinase
ACZ76_RS01170	COG0589	response to stress
ACZ76_RS01175	COG2130	NADP-dependent
ACZ76_RS01185	COG1285	pathogenesis
ACZ76_RS01190	COG0840	transmembrane signaling receptor activity
ACZ76_RS01210	COG1609	Transcriptional regulator
ACZ76_RS01215	COG3250	beta-galactosidase activity
ACZ76_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS01220	COG0604	alcohol dehydrogenase
ACZ76_RS01220	COG3321	synthase
ACZ76_RS01250	COG3121	Chaperone
ACZ76_RS01265	COG3121	Chaperone
ACZ76_RS01275	COG3121	Chaperone
ACZ76_RS01295	COG3228	Belongs to the MtfA family
ACZ76_RS01305	COG3423	Transcriptional regulator
ACZ76_RS01320	COG0471	metal ion transport
ACZ76_RS01335	COG3051	citrate lyase alpha subunit
ACZ76_RS01340	COG2301	Belongs to the HpcH HpaI aldolase family
ACZ76_RS01345	COG3052	prosthetic group binding
ACZ76_RS01350	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ACZ76_RS01355	COG3290	protein histidine kinase activity
ACZ76_RS01360	COG4565	transcriptional regulatory protein
ACZ76_RS01375	COG2271	Major facilitator Superfamily
ACZ76_RS01380	COG1840	ABC-type Fe3 transport system, periplasmic component
ACZ76_RS01390	COG3842	ATPase activity
ACZ76_RS01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS01405	COG2205	protein histidine kinase activity
ACZ76_RS01415	COG3121	Chaperone
ACZ76_RS01420	COG3188	usher protein
ACZ76_RS01430	COG3121	Chaperone
ACZ76_RS01435	COG1187	pseudouridine synthase activity
ACZ76_RS01465	COG3122	Protein conserved in bacteria
ACZ76_RS01485	COG4221	oxidoreductase activity
ACZ76_RS01490	COG0835	chemotaxis
ACZ76_RS01490	COG0784	Response regulator, receiver
ACZ76_RS01495	COG0583	DNA-binding transcription factor activity
ACZ76_RS01510	COG1349	DNA-binding transcription factor activity
ACZ76_RS01515	COG0352	thiamine-phosphate diphosphorylase activity
ACZ76_RS01525	COG0534	Mate efflux family protein
ACZ76_RS01530	COG0137	argininosuccinate synthase activity
ACZ76_RS01540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACZ76_RS01560	COG1492	cobalamin metabolic process
ACZ76_RS01625	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ACZ76_RS01635	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ACZ76_RS01695	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ACZ76_RS01710	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ACZ76_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
ACZ76_RS01730	COG4656	Part of a membrane complex involved in electron transport
ACZ76_RS01750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACZ76_RS01755	COG1648	precorrin-2 dehydrogenase activity
ACZ76_RS01755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACZ76_RS01760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACZ76_RS01775	COG1129	ABC transporter
ACZ76_RS01780	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS01790	COG2926	Belongs to the UPF0265 family
ACZ76_RS01795	COG1289	transmembrane transporter activity
ACZ76_RS01805	COG2925	Exonuclease
ACZ76_RS01810	COG0531	amino acid
ACZ76_RS01815	COG0371	Dehydrogenase
ACZ76_RS01820	COG1129	ABC transporter
ACZ76_RS01825	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS01830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ76_RS01835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACZ76_RS01840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACZ76_RS01845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACZ76_RS01850	COG0131	Imidazoleglycerol-phosphate dehydratase
ACZ76_RS01850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACZ76_RS01860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACZ76_RS01865	COG0107	imidazoleglycerol-phosphate synthase activity
ACZ76_RS01870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACZ76_RS01870	COG0140	phosphoribosyl-ATP diphosphatase activity
ACZ76_RS01875	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACZ76_RS01880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACZ76_RS01885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACZ76_RS01905	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ACZ76_RS01915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ76_RS01935	COG1253	flavin adenine dinucleotide binding
ACZ76_RS01940	COG3069	C4-dicarboxylate transmembrane transporter activity
ACZ76_RS01945	COG2982	Protein involved in outer membrane biogenesis
ACZ76_RS01955	COG0572	uridine kinase
ACZ76_RS01960	COG0489	protein tyrosine kinase activity
ACZ76_RS01965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACZ76_RS01965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACZ76_RS01980	COG2814	Major facilitator Superfamily
ACZ76_RS01985	COG1380	Effector of murein hydrolase LrgA
ACZ76_RS01990	COG1346	cytolysis
ACZ76_RS02000	COG0281	malic enzyme
ACZ76_RS02005	COG2949	membrane
ACZ76_RS02010	COG0298	carbon dioxide binding
ACZ76_RS02015	COG0375	protein maturation
ACZ76_RS02020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ76_RS02025	COG0651	ATP synthesis coupled electron transport
ACZ76_RS02030	COG0650	Formate hydrogenlyase subunit 4
ACZ76_RS02035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACZ76_RS02040	COG4237	Hydrogenase 4 membrane
ACZ76_RS02045	COG0651	ATP synthesis coupled electron transport
ACZ76_RS02050	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ACZ76_RS02050	COG3261	NADH dehydrogenase
ACZ76_RS02055	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACZ76_RS02060	COG3260	NADH ubiquinone oxidoreductase 20
ACZ76_RS02070	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ACZ76_RS02075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ76_RS02080	COG3383	formate dehydrogenase (NAD+) activity
ACZ76_RS02085	COG3604	Transcriptional regulator
ACZ76_RS02090	COG2116	formate transmembrane transporter activity
ACZ76_RS02115	COG2311	Membrane
ACZ76_RS02120	COG0302	gtp cyclohydrolase
ACZ76_RS02125	COG0477	Major facilitator Superfamily
ACZ76_RS02130	COG0583	DNA-binding transcription factor activity
ACZ76_RS02165	COG0477	Major facilitator Superfamily
ACZ76_RS02175	COG0303	'Molybdopterin
ACZ76_RS02180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACZ76_RS02185	COG0488	(ABC) transporter
ACZ76_RS02205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACZ76_RS02220	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ACZ76_RS02235	COG4106	trans-aconitate 2-methyltransferase activity
ACZ76_RS02240	COG0783	Belongs to the Dps family
ACZ76_RS02245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACZ76_RS02250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS02255	COG0765	amino acid transport
ACZ76_RS02260	COG1126	abc transporter atp-binding protein
ACZ76_RS02270	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ACZ76_RS02275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACZ76_RS02290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACZ76_RS02295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACZ76_RS02315	COG0697	spore germination
ACZ76_RS02325	COG1982	Orn Lys Arg decarboxylase major
ACZ76_RS02330	COG0531	amino acid
ACZ76_RS02340	COG1174	glycine betaine transport
ACZ76_RS02345	COG1125	glycine betaine transport
ACZ76_RS02350	COG1174	glycine betaine transport
ACZ76_RS02355	COG1732	Glycine betaine
ACZ76_RS02370	COG2897	thiosulfate sulfurtransferase activity
ACZ76_RS02380	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ACZ76_RS02400	COG4807	Protein conserved in bacteria
ACZ76_RS02415	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ACZ76_RS02425	COG2261	transglycosylase associated protein
ACZ76_RS02445	COG0277	FAD linked oxidase domain protein
ACZ76_RS02450	COG1686	Belongs to the peptidase S11 family
ACZ76_RS02465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACZ76_RS02470	COG0513	Belongs to the DEAD box helicase family
ACZ76_RS02475	COG1309	transcriptional regulator
ACZ76_RS02480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS02485	COG1131	(ABC) transporter
ACZ76_RS02490	COG0842	Transport permease protein
ACZ76_RS02495	COG0842	Transport permease protein
ACZ76_RS02500	COG0670	Belongs to the BI1 family
ACZ76_RS02505	COG0314	molybdopterin synthase activity
ACZ76_RS02510	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACZ76_RS02515	COG0315	cyclic pyranopterin monophosphate synthase activity
ACZ76_RS02520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACZ76_RS02525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACZ76_RS02530	COG4628	conserved protein (DUF2132)
ACZ76_RS02535	COG0556	nucleotide-excision repair
ACZ76_RS02550	COG2226	methyltransferase
ACZ76_RS02560	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACZ76_RS02575	COG0561	phosphatase activity
ACZ76_RS02580	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ACZ76_RS02585	COG0622	Phosphoesterase
ACZ76_RS02595	COG1090	epimerase
ACZ76_RS02605	COG4160	amino acid transport
ACZ76_RS02610	COG4215	(ABC) transporter
ACZ76_RS02615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS02620	COG0163	prenyltransferase activity
ACZ76_RS02625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACZ76_RS02630	COG1286	toxin biosynthetic process
ACZ76_RS02635	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ACZ76_RS02640	COG0285	dihydrofolate synthase activity
ACZ76_RS02650	COG0586	Pfam SNARE associated Golgi protein
ACZ76_RS02660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACZ76_RS02680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACZ76_RS02690	COG4232	protein-disulfide reductase activity
ACZ76_RS02705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACZ76_RS02715	COG1794	racemase activity, acting on amino acids and derivatives
ACZ76_RS02725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACZ76_RS02740	COG3101	peptidyl-lysine hydroxylation
ACZ76_RS02745	COG0730	response to heat
ACZ76_RS02750	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ACZ76_RS02755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACZ76_RS02760	COG2890	protein-(glutamine-N5) methyltransferase activity
ACZ76_RS02765	COG2840	Smr protein MutS2
ACZ76_RS02775	COG2062	phosphohistidine phosphatase, SixA
ACZ76_RS02780	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACZ76_RS02780	COG1024	Enoyl-CoA hydratase
ACZ76_RS02785	COG0183	Belongs to the thiolase family
ACZ76_RS02790	COG3691	Protein conserved in bacteria
ACZ76_RS02815	COG3088	subunit of a heme lyase
ACZ76_RS02815	COG4235	cytochrome complex assembly
ACZ76_RS02820	COG3088	subunit of a heme lyase
ACZ76_RS02820	COG4235	cytochrome complex assembly
ACZ76_RS02825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACZ76_RS02830	COG1138	Cytochrome C-type biogenesis protein
ACZ76_RS02835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ACZ76_RS02840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACZ76_RS02845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACZ76_RS02850	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACZ76_RS02865	COG2824	Alkylphosphonate utilization operon protein PhnA
ACZ76_RS02870	COG1695	Transcriptional regulator
ACZ76_RS02880	COG2723	6-phospho-beta-galactosidase activity
ACZ76_RS02885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS02885	COG1263	PTS System
ACZ76_RS02890	COG1609	Transcriptional regulator
ACZ76_RS02895	COG2353	YceI-like domain
ACZ76_RS02900	COG3038	cytochrome b561
ACZ76_RS02915	COG1127	ABC transporter
ACZ76_RS02920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACZ76_RS02940	COG0531	amino acid
ACZ76_RS02945	COG2951	lytic endotransglycosylase activity
ACZ76_RS02970	COG0243	molybdopterin cofactor binding
ACZ76_RS02975	COG0437	4 iron, 4 sulfur cluster binding
ACZ76_RS02980	COG3302	dmso reductase anchor subunit
ACZ76_RS02985	COG3381	protein complex oligomerization
ACZ76_RS03005	COG1598	PFAM Uncharacterised protein family UPF0150
ACZ76_RS03010	COG3038	cytochrome b561
ACZ76_RS03015	COG0436	Aminotransferase
ACZ76_RS03030	COG3275	phosphorelay sensor kinase activity
ACZ76_RS03035	COG3279	Response regulator of the LytR AlgR family
ACZ76_RS03040	COG2223	nitrite transmembrane transporter activity
ACZ76_RS03045	COG0837	glucose binding
ACZ76_RS03060	COG3961	Belongs to the TPP enzyme family
ACZ76_RS03065	COG0667	Aldo Keto reductase
ACZ76_RS03075	COG1914	H( )-stimulated, divalent metal cation uptake system
ACZ76_RS03080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACZ76_RS03105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACZ76_RS03135	COG3530	Putative quorum-sensing-regulated virulence factor
ACZ76_RS03140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACZ76_RS03150	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ACZ76_RS03160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS03165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACZ76_RS03175	COG2205	protein histidine kinase activity
ACZ76_RS03180	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS03185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS03205	COG4208	sulfate ABC transporter
ACZ76_RS03210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACZ76_RS03215	COG4150	thiosulfate binding
ACZ76_RS03225	COG1737	Transcriptional regulator
ACZ76_RS03230	COG2731	YhcH YjgK YiaL family protein
ACZ76_RS03245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACZ76_RS03250	COG2837	iron assimilation
ACZ76_RS03265	COG3111	PFAM Bacterial OB fold (BOF) protein
ACZ76_RS03270	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS03275	COG2897	thiosulfate sulfurtransferase activity
ACZ76_RS03295	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS03300	COG1129	ABC transporter
ACZ76_RS03310	COG0456	acetyltransferase
ACZ76_RS03315	COG0408	coproporphyrinogen oxidase activity
ACZ76_RS03320	COG1671	Belongs to the UPF0178 family
ACZ76_RS03330	COG0494	nUDIX hydrolase
ACZ76_RS03335	COG3005	denitrification pathway
ACZ76_RS03340	COG3043	anaerobic respiration
ACZ76_RS03345	COG0243	molybdopterin cofactor binding
ACZ76_RS03350	COG3062	negative regulation of establishment of protein localization
ACZ76_RS03355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ76_RS03355	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ76_RS03360	COG2197	response regulator
ACZ76_RS03370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ76_RS03380	COG3842	ATPase activity
ACZ76_RS03385	COG1175	transmembrane transport
ACZ76_RS03400	COG1393	Belongs to the ArsC family
ACZ76_RS03405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACZ76_RS03410	COG1876	peptidase activity
ACZ76_RS03420	COG0400	carboxylic ester hydrolase activity
ACZ76_RS03425	COG1444	tRNA N-acetyltransferase activity
ACZ76_RS03430	COG2707	UPF0756 membrane protein
ACZ76_RS03435	COG2321	neutral zinc metallopeptidase
ACZ76_RS03440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACZ76_RS03445	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ACZ76_RS03450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACZ76_RS03455	COG2716	regulation of RNA biosynthetic process
ACZ76_RS03460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACZ76_RS03465	COG0628	permease
ACZ76_RS03470	COG4783	chaperone-mediated protein folding
ACZ76_RS03475	COG1393	Belongs to the ArsC family
ACZ76_RS03480	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACZ76_RS03485	COG2233	PERMEase
ACZ76_RS03495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACZ76_RS03500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACZ76_RS03505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACZ76_RS03525	COG0581	inorganic phosphate transmembrane transporter activity
ACZ76_RS03530	COG0573	inorganic phosphate transmembrane transporter activity
ACZ76_RS03535	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACZ76_RS03550	COG2239	Acts as a magnesium transporter
ACZ76_RS03555	COG5002	protein histidine kinase activity
ACZ76_RS03555	COG5001	Diguanylate cyclase
ACZ76_RS03555	COG3447	MASE1 domain protein
ACZ76_RS03560	COG0443	Heat shock 70 kDa protein
ACZ76_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS03580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ76_RS03590	COG0477	Major facilitator Superfamily
ACZ76_RS03595	COG2205	protein histidine kinase activity
ACZ76_RS03600	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS03605	COG3422	double-strand break repair
ACZ76_RS03610	COG0826	peptidase U32
ACZ76_RS03615	COG1597	lipid kinase activity
ACZ76_RS03620	COG3730	PTS system glucitol sorbitol-specific
ACZ76_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS03640	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS03645	COG1349	DNA-binding transcription factor activity
ACZ76_RS03665	COG0351	phosphomethylpyrimidine kinase
ACZ76_RS03690	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACZ76_RS03690	COG0519	Catalyzes the synthesis of GMP from XMP
ACZ76_RS03695	COG0517	IMP dehydrogenase activity
ACZ76_RS03695	COG0516	GMP reductase activity
ACZ76_RS03700	COG1570	exodeoxyribonuclease VII activity
ACZ76_RS03705	COG1645	bacterial-type flagellum-dependent swarming motility
ACZ76_RS03715	COG1160	GTP binding
ACZ76_RS03720	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACZ76_RS03725	COG2976	Protein conserved in bacteria
ACZ76_RS03765	COG4953	penicillin-binding protein 1C
ACZ76_RS03770	COG2373	Large extracellular alpha-helical protein
ACZ76_RS03775	COG3468	outer membrane autotransporter barrel domain protein
ACZ76_RS03780	COG3468	outer membrane autotransporter barrel domain protein
ACZ76_RS03795	COG2975	iron-sulfur cluster assembly
ACZ76_RS03800	COG0633	Ferredoxin
ACZ76_RS03805	COG0443	Heat shock 70 kDa protein
ACZ76_RS03820	COG0822	iron-sulfur transferase activity
ACZ76_RS03830	COG1959	2 iron, 2 sulfur cluster binding
ACZ76_RS03835	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACZ76_RS03840	COG0483	inositol monophosphate 1-phosphatase activity
ACZ76_RS03845	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ACZ76_RS03850	COG3683	transport system, periplasmic component
ACZ76_RS03855	COG3711	transcriptional antiterminator
ACZ76_RS03860	COG2814	Major facilitator Superfamily
ACZ76_RS03870	COG1017	nitric oxide dioxygenase activity
ACZ76_RS03870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACZ76_RS03875	COG2188	Transcriptional regulator
ACZ76_RS03885	COG3457	Alanine racemase
ACZ76_RS03890	COG0347	Belongs to the P(II) protein family
ACZ76_RS03895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACZ76_RS03895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACZ76_RS03900	COG2204	response regulator
ACZ76_RS03905	COG3170	Tfp pilus assembly protein FimV
ACZ76_RS03910	COG2205	protein histidine kinase activity
ACZ76_RS03925	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ACZ76_RS03940	COG0560	Phosphoserine phosphatase
ACZ76_RS03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS03945	COG1263	PTS System
ACZ76_RS03955	COG1737	Transcriptional regulator
ACZ76_RS03960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ76_RS03965	COG2610	gluconate transmembrane transporter activity
ACZ76_RS03970	COG0736	holo-[acyl-carrier-protein] synthase activity
ACZ76_RS03975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACZ76_RS03980	COG1381	Involved in DNA repair and RecF pathway recombination
ACZ76_RS03985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACZ76_RS04000	COG0481	GTPase activity
ACZ76_RS04010	COG3086	response to oxidative stress
ACZ76_RS04020	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ACZ76_RS04030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACZ76_RS04035	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACZ76_RS04040	COG0513	Belongs to the DEAD box helicase family
ACZ76_RS04045	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ACZ76_RS04050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACZ76_RS04055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACZ76_RS04060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACZ76_RS04065	COG0497	DNA recombination
ACZ76_RS04070	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACZ76_RS04080	COG2867	negative regulation of translational initiation
ACZ76_RS04085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACZ76_RS04090	COG0582	viral genome integration into host DNA
ACZ76_RS04145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACZ76_RS04190	COG0582	viral genome integration into host DNA
ACZ76_RS04215	COG1917	Cupin 2, conserved barrel domain protein
ACZ76_RS04215	COG2169	Transcriptional regulator
ACZ76_RS04220	COG1447	Phosphotransferase system cellobiose-specific component IIA
ACZ76_RS04225	COG2723	6-phospho-beta-galactosidase activity
ACZ76_RS04230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ACZ76_RS04235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ACZ76_RS04240	COG2133	pyrroloquinoline quinone binding
ACZ76_RS04255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACZ76_RS04265	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ACZ76_RS04270	COG4413	Urea transporter
ACZ76_RS04295	COG0804	urea catabolic process
ACZ76_RS04300	COG0832	Belongs to the urease beta subunit family
ACZ76_RS04305	COG0831	urea catabolic process
ACZ76_RS04320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACZ76_RS04325	COG0601	transmembrane transport
ACZ76_RS04340	COG1278	Cold shock
ACZ76_RS04365	COG4575	ribosome binding
ACZ76_RS04375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACZ76_RS04380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACZ76_RS04385	COG1780	Probably involved in ribonucleotide reductase function
ACZ76_RS04395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACZ76_RS04400	COG4175	Glycine betaine
ACZ76_RS04405	COG4176	ABC-type proline glycine betaine transport system permease component
ACZ76_RS04410	COG2113	Glycine betaine
ACZ76_RS04425	COG0328	RNA-DNA hybrid ribonuclease activity
ACZ76_RS04430	COG2226	methyltransferase
ACZ76_RS04435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACZ76_RS04440	COG1388	LysM domain
ACZ76_RS04440	COG0741	lytic transglycosylase activity
ACZ76_RS04445	COG3021	interspecies interaction between organisms
ACZ76_RS04450	COG0656	L-ascorbic acid biosynthetic process
ACZ76_RS04485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ACZ76_RS04495	COG2011	ABC-type metal ion transport system permease component
ACZ76_RS04500	COG1464	Belongs to the NlpA lipoprotein family
ACZ76_RS04510	COG1720	tRNA m6t6A37 methyltransferase activity
ACZ76_RS04520	COG3015	lipoprotein NlpE involved in copper resistance
ACZ76_RS04530	COG4681	YaeQ
ACZ76_RS04540	COG4568	rho-dependent transcription termination
ACZ76_RS04555	COG0346	lactoylglutathione lyase activity
ACZ76_RS04570	COG0825	malonyl-CoA metabolic process
ACZ76_RS04575	COG0587	DNA-directed DNA polymerase activity
ACZ76_RS04580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACZ76_RS04590	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACZ76_RS04600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACZ76_RS04605	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ACZ76_RS04615	COG0750	zinc metalloprotease
ACZ76_RS04620	COG0575	Belongs to the CDS family
ACZ76_RS04630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACZ76_RS04635	COG0233	cytoplasmic translational termination
ACZ76_RS04640	COG0528	UMP kinase activity
ACZ76_RS04645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACZ76_RS04650	COG0052	Belongs to the universal ribosomal protein uS2 family
ACZ76_RS04660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ACZ76_RS04665	COG2171	N-acyltransferase activity
ACZ76_RS04685	COG0564	pseudouridine synthase activity
ACZ76_RS04690	COG3098	single-species biofilm formation
ACZ76_RS04700	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACZ76_RS04700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACZ76_RS04705	COG1611	Belongs to the LOG family
ACZ76_RS04715	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ACZ76_RS04720	COG2363	Small membrane protein
ACZ76_RS04725	COG0583	DNA-binding transcription factor activity
ACZ76_RS04735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACZ76_RS04740	COG2166	iron-sulfur cluster assembly
ACZ76_RS04745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACZ76_RS04750	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ACZ76_RS04770	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACZ76_RS04775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACZ76_RS04775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACZ76_RS04780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACZ76_RS04785	COG1074	ATP-dependent DNA helicase activity
ACZ76_RS04790	COG1025	Belongs to the peptidase M16 family
ACZ76_RS04795	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACZ76_RS04805	COG4795	General secretion pathway protein
ACZ76_RS04825	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACZ76_RS04835	COG1051	belongs to the nudix hydrolase family
ACZ76_RS04840	COG3066	DNA modification
ACZ76_RS04845	COG0861	Integral membrane protein TerC family
ACZ76_RS04850	COG0667	Aldo Keto reductase
ACZ76_RS04860	COG0477	Major facilitator Superfamily
ACZ76_RS04865	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ76_RS04865	COG0204	Acyl-transferase
ACZ76_RS04875	COG1609	Transcriptional regulator
ACZ76_RS04885	COG0583	DNA-binding transcription factor activity
ACZ76_RS04890	COG2814	Major facilitator Superfamily
ACZ76_RS04895	COG0583	DNA-binding transcription factor activity
ACZ76_RS04920	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACZ76_RS04955	COG1459	type II secretion system
ACZ76_RS04960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACZ76_RS04980	COG1733	regulation of RNA biosynthetic process
ACZ76_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS04995	COG0484	heat shock protein binding
ACZ76_RS05005	COG2271	Major facilitator Superfamily
ACZ76_RS05020	COG1522	sequence-specific DNA binding
ACZ76_RS05025	COG3706	GGDEF domain
ACZ76_RS05030	COG4319	ketosteroid isomerase
ACZ76_RS05050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ACZ76_RS05055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACZ76_RS05060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACZ76_RS05065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACZ76_RS05070	COG4974	Belongs to the 'phage' integrase family
ACZ76_RS05075	COG0716	FMN binding
ACZ76_RS05080	COG4452	Inner membrane protein CreD
ACZ76_RS05085	COG2205	protein histidine kinase activity
ACZ76_RS05090	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS05105	COG0354	folic acid binding
ACZ76_RS05110	COG1272	protein, Hemolysin III
ACZ76_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS05120	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACZ76_RS05120	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACZ76_RS05125	COG0509	glycine decarboxylation via glycine cleavage system
ACZ76_RS05130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACZ76_RS05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACZ76_RS05140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACZ76_RS05145	COG0006	proline dipeptidase activity
ACZ76_RS05150	COG3079	Belongs to the UPF0149 family
ACZ76_RS05155	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ACZ76_RS05160	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACZ76_RS05165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACZ76_RS05170	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACZ76_RS05175	COG0583	DNA-binding transcription factor activity
ACZ76_RS05185	COG1279	arginine transmembrane transporter activity
ACZ76_RS05200	COG0191	fructose-bisphosphate aldolase activity
ACZ76_RS05205	COG0126	phosphoglycerate kinase activity
ACZ76_RS05210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACZ76_RS05220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACZ76_RS05225	COG0501	Belongs to the peptidase M48B family
ACZ76_RS05235	COG1166	arginine decarboxylase activity
ACZ76_RS05240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACZ76_RS05255	COG0640	Transcriptional regulator
ACZ76_RS05260	COG3091	SprT-like family
ACZ76_RS05265	COG2356	endonuclease I
ACZ76_RS05270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACZ76_RS05275	COG0189	ligase activity
ACZ76_RS05280	COG1678	Uncharacterized ACR, COG1678
ACZ76_RS05285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACZ76_RS05290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACZ76_RS05300	COG2805	Type II/IV secretion system protein
ACZ76_RS05305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACZ76_RS05310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACZ76_RS05315	COG0762	integral membrane protein
ACZ76_RS05320	COG1872	DUF167
ACZ76_RS05325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACZ76_RS05330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACZ76_RS05335	COG2826	transposase and inactivated derivatives, IS30 family
ACZ76_RS05355	COG3171	Protein conserved in bacteria
ACZ76_RS05360	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACZ76_RS05365	COG1194	a g-specific adenine glycosylase
ACZ76_RS05375	COG0741	lytic transglycosylase activity
ACZ76_RS05380	COG1982	Orn Lys Arg decarboxylase major
ACZ76_RS05440	COG3675	Pfam Lipase (class 3)
ACZ76_RS05515	COG3047	cAMP biosynthetic process
ACZ76_RS05515	COG2885	chlorophyll binding
ACZ76_RS05540	COG0288	reversible hydration of carbon dioxide
ACZ76_RS05550	COG1289	transmembrane transporter activity
ACZ76_RS05585	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACZ76_RS05590	COG1737	Transcriptional regulator
ACZ76_RS05595	COG3069	C4-dicarboxylate transmembrane transporter activity
ACZ76_RS05600	COG0281	malic enzyme
ACZ76_RS05615	COG4604	ABC transporter, ATP-binding protein
ACZ76_RS05620	COG4605	iron ion homeostasis
ACZ76_RS05630	COG4607	ABC-type enterochelin transport system periplasmic component
ACZ76_RS05635	COG0477	Major facilitator Superfamily
ACZ76_RS05640	COG1609	Transcriptional regulator
ACZ76_RS05650	COG1283	sodium-dependent phosphate transmembrane transporter activity
ACZ76_RS05670	COG4302	ethanolamine ammonia-lyase activity
ACZ76_RS05675	COG4303	Ethanolamine ammonia lyase large subunit
ACZ76_RS05690	COG2197	response regulator
ACZ76_RS05705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS05710	COG5001	Diguanylate cyclase
ACZ76_RS05715	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACZ76_RS05720	COG0309	Hydrogenase expression formation protein (HypE)
ACZ76_RS05725	COG0409	Hydrogenase expression formation protein
ACZ76_RS05730	COG0298	carbon dioxide binding
ACZ76_RS05735	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ACZ76_RS05745	COG1773	rubredoxin
ACZ76_RS05750	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ACZ76_RS05755	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ACZ76_RS05760	COG5557	Pfam Polysulphide reductase, NrfD
ACZ76_RS05765	COG0437	4 iron, 4 sulfur cluster binding
ACZ76_RS05770	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ACZ76_RS05785	COG3133	Outer membrane lipoprotein
ACZ76_RS05795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ACZ76_RS05800	COG1191	sigma factor activity
ACZ76_RS05820	COG1516	flagellar protein fliS
ACZ76_RS05825	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACZ76_RS05830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACZ76_RS05835	COG3710	Transcriptional regulator
ACZ76_RS05865	COG1706	bacterial-type flagellum-dependent cell motility
ACZ76_RS05875	COG4786	Flagellar basal body rod
ACZ76_RS05890	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACZ76_RS05895	COG1558	bacterial-type flagellum-dependent cell motility
ACZ76_RS05900	COG1815	bacterial-type flagellum-dependent cell motility
ACZ76_RS05945	COG1677	Flagellar hook-basal body complex protein FliE
ACZ76_RS05970	COG1987	bacterial-type flagellum assembly
ACZ76_RS05975	COG1684	flagellar biosynthetic protein fliR
ACZ76_RS05995	COG0840	transmembrane signaling receptor activity
ACZ76_RS06000	COG4592	Periplasmic binding protein
ACZ76_RS06010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACZ76_RS06015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACZ76_RS06020	COG1120	ATPase activity
ACZ76_RS06045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS06050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ76_RS06075	COG4964	Belongs to the GSP D family
ACZ76_RS06130	COG0848	biopolymer transport protein
ACZ76_RS06145	COG0586	Pfam SNARE associated Golgi protein
ACZ76_RS06150	COG2207	Transcriptional regulator
ACZ76_RS06155	COG1979	alcohol dehydrogenase
ACZ76_RS06160	COG0656	L-ascorbic acid biosynthetic process
ACZ76_RS06170	COG2132	Multicopper oxidase
ACZ76_RS06175	COG0204	Acyl-transferase
ACZ76_RS06180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACZ76_RS06185	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACZ76_RS06190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACZ76_RS06205	COG3150	esterase
ACZ76_RS06210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACZ76_RS06215	COG3151	Protein conserved in bacteria
ACZ76_RS06220	COG0494	nUDIX hydrolase
ACZ76_RS06225	COG1538	Outer membrane efflux protein
ACZ76_RS06230	COG5463	Belongs to the UPF0441 family
ACZ76_RS06235	COG0754	glutathionylspermidine amidase activity
ACZ76_RS06240	COG3384	dioxygenase
ACZ76_RS06245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACZ76_RS06255	COG0531	amino acid
ACZ76_RS06260	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ACZ76_RS06260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ACZ76_RS06265	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACZ76_RS06270	COG3025	triphosphatase activity
ACZ76_RS06275	COG4991	sh3 domain protein
ACZ76_RS06280	COG0617	tRNA 3'-terminal CCA addition
ACZ76_RS06285	COG1968	undecaprenyl-diphosphatase activity
ACZ76_RS06290	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACZ76_RS06295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACZ76_RS06300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACZ76_RS06305	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACZ76_RS06310	COG0358	DNA primase activity
ACZ76_RS06325	COG2814	Major facilitator Superfamily
ACZ76_RS06330	COG3247	response to pH
ACZ76_RS06335	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACZ76_RS06335	COG1902	pentaerythritol trinitrate reductase activity
ACZ76_RS06345	COG2813	Specifically methylates the guanine in position
ACZ76_RS06355	COG1451	nucleotide metabolic process
ACZ76_RS06360	COG0673	inositol 2-dehydrogenase activity
ACZ76_RS06365	COG0861	Integral membrane protein TerC family
ACZ76_RS06370	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ACZ76_RS06380	COG2721	sulfolactate sulfo-lyase activity
ACZ76_RS06385	COG0246	Mannitol dehydrogenase
ACZ76_RS06390	COG1904	glucuronate isomerase
ACZ76_RS06395	COG2271	Major facilitator Superfamily
ACZ76_RS06415	COG0586	Pfam SNARE associated Golgi protein
ACZ76_RS06430	COG4575	ribosome binding
ACZ76_RS06435	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ACZ76_RS06445	COG2259	Doxx family
ACZ76_RS06450	COG0435	Glutathione S-transferase
ACZ76_RS06455	COG0583	DNA-binding transcription factor activity
ACZ76_RS06460	COG1741	Belongs to the pirin family
ACZ76_RS06465	COG0583	DNA-binding transcription factor activity
ACZ76_RS06470	COG4566	intracellular signal transduction
ACZ76_RS06475	COG0583	DNA-binding transcription factor activity
ACZ76_RS06480	COG1064	alcohol dehydrogenase
ACZ76_RS06510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACZ76_RS06520	COG0792	nuclease activity
ACZ76_RS06525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ACZ76_RS06530	COG2823	Periplasmic or secreted lipoprotein
ACZ76_RS06535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACZ76_RS06540	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACZ76_RS06545	COG2198	Histidine kinase
ACZ76_RS06545	COG5002	protein histidine kinase activity
ACZ76_RS06545	COG0784	Response regulator, receiver
ACZ76_RS06550	COG1242	4 iron, 4 sulfur cluster binding
ACZ76_RS06555	COG0069	glutamate synthase activity
ACZ76_RS06555	COG0067	glutamate synthase
ACZ76_RS06555	COG0070	glutamate synthase
ACZ76_RS06560	COG0493	'glutamate synthase
ACZ76_RS06570	COG2969	positive regulation of protein catabolic process
ACZ76_RS06575	COG0625	glutathione transferase activity
ACZ76_RS06580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACZ76_RS06585	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACZ76_RS06590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACZ76_RS06595	COG3105	Protein conserved in bacteria
ACZ76_RS06600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACZ76_RS06605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACZ76_RS06615	COG5007	Belongs to the BolA IbaG family
ACZ76_RS06620	COG3113	response to antibiotic
ACZ76_RS06625	COG2854	intermembrane phospholipid transfer
ACZ76_RS06630	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACZ76_RS06635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACZ76_RS06640	COG1127	ABC transporter
ACZ76_RS06645	COG0530	calcium, potassium:sodium antiporter activity
ACZ76_RS06650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACZ76_RS06650	COG0517	IMP dehydrogenase activity
ACZ76_RS06655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACZ76_RS06660	COG3117	lipopolysaccharide transmembrane transporter activity
ACZ76_RS06665	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACZ76_RS06670	COG1137	ATPase activity
ACZ76_RS06675	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACZ76_RS06695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS06700	COG0540	Belongs to the ATCase OTCase family
ACZ76_RS06705	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ACZ76_RS06715	COG2308	Evidence 4 Homologs of previously reported genes of
ACZ76_RS06735	COG0366	Alpha amylase catalytic
ACZ76_RS06740	COG1263	PTS System
ACZ76_RS06740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS06750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACZ76_RS06755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS06755	COG3711	transcriptional antiterminator
ACZ76_RS06760	COG2706	6-phosphogluconolactonase activity
ACZ76_RS06775	COG3964	amidohydrolase
ACZ76_RS06805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACZ76_RS06810	COG3783	Cytochrome b(562)
ACZ76_RS06815	COG0312	modulator of DNA gyrase
ACZ76_RS06820	COG3028	Belongs to the UPF0307 family
ACZ76_RS06825	COG2732	(Barnase) inhibitor
ACZ76_RS06835	COG1012	belongs to the aldehyde dehydrogenase family
ACZ76_RS06840	COG1289	transmembrane transporter activity
ACZ76_RS06845	COG1566	PFAM secretion protein HlyD family protein
ACZ76_RS06855	COG0583	DNA-binding transcription factor activity
ACZ76_RS06860	COG0312	modulator of DNA gyrase
ACZ76_RS06865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACZ76_RS06870	COG3164	Protein of unknown function
ACZ76_RS06875	COG1530	ribonuclease E activity
ACZ76_RS06880	COG0424	maF-like protein
ACZ76_RS06885	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACZ76_RS06890	COG1792	Involved in formation and maintenance of cell shape
ACZ76_RS06895	COG1077	Cell shape determining protein MreB Mrl
ACZ76_RS06900	COG2199	diguanylate cyclase activity
ACZ76_RS06900	COG2200	EAL domain
ACZ76_RS06905	COG0604	alcohol dehydrogenase
ACZ76_RS06915	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ACZ76_RS06920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ACZ76_RS06925	COG0511	ligase activity, forming carbon-carbon bonds
ACZ76_RS06930	COG0439	Biotin carboxylase
ACZ76_RS06935	COG3924	membrane
ACZ76_RS06940	COG4145	pantothenate transmembrane transporter activity
ACZ76_RS06945	COG2264	protein methyltransferase activity
ACZ76_RS06950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACZ76_RS06955	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACZ76_RS06965	COG1802	Transcriptional regulator
ACZ76_RS06965	COG4626	Terminase
ACZ76_RS07055	COG3706	GGDEF domain
ACZ76_RS07060	COG3133	Outer membrane lipoprotein
ACZ76_RS07065	COG1278	Cold shock
ACZ76_RS07070	COG1278	Cold shock
ACZ76_RS07075	COG0471	metal ion transport
ACZ76_RS07085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACZ76_RS07095	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS07100	COG1129	ABC transporter
ACZ76_RS07110	COG1560	Kdo2-lipid A biosynthetic process
ACZ76_RS07115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS07120	COG4597	amino acid ABC transporter
ACZ76_RS07125	COG0765	amino acid transport
ACZ76_RS07130	COG1126	abc transporter atp-binding protein
ACZ76_RS07145	COG1380	Effector of murein hydrolase LrgA
ACZ76_RS07150	COG0583	DNA-binding transcription factor activity
ACZ76_RS07155	COG0025	NhaP-type Na H and K H
ACZ76_RS07165	COG2252	PERMEase
ACZ76_RS07175	COG0629	single-stranded DNA binding
ACZ76_RS07180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACZ76_RS07185	COG2315	Protein conserved in bacteria
ACZ76_RS07190	COG1448	Aminotransferase
ACZ76_RS07220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACZ76_RS07225	COG0735	belongs to the Fur family
ACZ76_RS07230	COG3237	CsbD-like
ACZ76_RS07235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACZ76_RS07240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACZ76_RS07245	COG2937	Belongs to the GPAT DAPAT family
ACZ76_RS07250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACZ76_RS07255	COG3161	chorismate lyase activity
ACZ76_RS07270	COG4580	involved in the transport of maltose and maltodextrins
ACZ76_RS07285	COG1175	transmembrane transport
ACZ76_RS07290	COG3833	ABC-type maltose transport systems, permease component
ACZ76_RS07295	COG3223	Belongs to the PsiE family
ACZ76_RS07305	COG0527	aspartate kinase activity
ACZ76_RS07330	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ACZ76_RS07335	COG2224	Isocitrate lyase
ACZ76_RS07340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACZ76_RS07345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ACZ76_RS07395	COG0151	Belongs to the GarS family
ACZ76_RS07415	COG1515	deoxyribonuclease V activity
ACZ76_RS07425	COG2816	NAD+ diphosphatase activity
ACZ76_RS07430	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ACZ76_RS07445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACZ76_RS07450	COG2104	thiamine diphosphate biosynthetic process
ACZ76_RS07455	COG2022	thiamine diphosphate biosynthetic process
ACZ76_RS07475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACZ76_RS07480	COG0085	RNA polymerase activity
ACZ76_RS07485	COG0222	ribosome binding
ACZ76_RS07490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACZ76_RS07495	COG0081	regulation of translation
ACZ76_RS07500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACZ76_RS07505	COG0250	Participates in transcription elongation, termination and antitermination
ACZ76_RS07545	COG1072	(Pantothenic acid kinase))
ACZ76_RS07580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACZ76_RS07585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACZ76_RS07590	COG0009	L-threonylcarbamoyladenylate synthase
ACZ76_RS07595	COG0551	DNA topoisomerase type I activity
ACZ76_RS07605	COG0758	DNA mediated transformation
ACZ76_RS07610	COG0242	peptide deformylase activity
ACZ76_RS07615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACZ76_RS07620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACZ76_RS07620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACZ76_RS07630	COG1970	mechanosensitive ion channel activity
ACZ76_RS07635	COG3036	rescue of stalled ribosome
ACZ76_RS07640	COG0789	Transcriptional regulator
ACZ76_RS07650	COG0203	ribosomal protein L17
ACZ76_RS07660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACZ76_RS07665	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACZ76_RS07670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACZ76_RS07675	COG0201	protein transport
ACZ76_RS07680	COG0200	Binds to the 23S rRNA
ACZ76_RS07685	COG1841	ribosomal large subunit assembly
ACZ76_RS07690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACZ76_RS07695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACZ76_RS07700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACZ76_RS07710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACZ76_RS07725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACZ76_RS07730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACZ76_RS07735	COG0255	Belongs to the universal ribosomal protein uL29 family
ACZ76_RS07740	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACZ76_RS07745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACZ76_RS07750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACZ76_RS07755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACZ76_RS07760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACZ76_RS07765	COG0089	rRNA binding
ACZ76_RS07775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACZ76_RS07780	COG0051	transcription antitermination factor activity, RNA binding
ACZ76_RS07790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACZ76_RS07800	COG0049	tRNA binding
ACZ76_RS07805	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACZ76_RS07810	COG2168	tRNA wobble position uridine thiolation
ACZ76_RS07815	COG2923	Belongs to the DsrF TusC family
ACZ76_RS07820	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACZ76_RS07825	COG2964	Protein conserved in bacteria
ACZ76_RS07830	COG0545	Peptidyl-prolyl cis-trans isomerase
ACZ76_RS07840	COG1047	Peptidyl-prolyl cis-trans
ACZ76_RS07845	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACZ76_RS07855	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACZ76_RS07860	COG0488	(ABC) transporter
ACZ76_RS07865	COG1216	Glycosyl transferase, family 2
ACZ76_RS07870	COG2175	clavaminate synthase activity
ACZ76_RS07875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACZ76_RS07885	COG4521	taurine ABC transporter
ACZ76_RS07900	COG0429	hydrolase of the alpha beta-hydrolase fold
ACZ76_RS07905	COG3089	Belongs to the UPF0270 family
ACZ76_RS07910	COG3954	Phosphoribulokinase
ACZ76_RS07915	COG1765	OsmC-like protein
ACZ76_RS07925	COG1289	transmembrane transporter activity
ACZ76_RS07950	COG0433	COG0433 Predicted ATPase
ACZ76_RS07955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACZ76_RS07960	COG1486	melibiose metabolic process
ACZ76_RS07980	COG0738	Major facilitator superfamily
ACZ76_RS07985	COG0402	S-adenosylhomocysteine deaminase activity
ACZ76_RS07990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACZ76_RS08005	COG1648	precorrin-2 dehydrogenase activity
ACZ76_RS08005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACZ76_RS08010	COG0180	Tryptophanyl-tRNA synthetase
ACZ76_RS08020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACZ76_RS08040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACZ76_RS08045	COG4796	Type ii and iii secretion system protein
ACZ76_RS08070	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ACZ76_RS08075	COG0494	nUDIX hydrolase
ACZ76_RS08085	COG1011	Hydrolase
ACZ76_RS08090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACZ76_RS08100	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACZ76_RS08115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACZ76_RS08140	COG2183	response to ionizing radiation
ACZ76_RS08145	COG1918	ferrous iron import across plasma membrane
ACZ76_RS08165	COG0596	Alpha beta hydrolase
ACZ76_RS08175	COG0316	Belongs to the HesB IscA family
ACZ76_RS08175	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACZ76_RS08180	COG1640	4-alpha-glucanotransferase
ACZ76_RS08185	COG0058	SHG alpha-glucan phosphorylase activity
ACZ76_RS08190	COG2909	trisaccharide binding
ACZ76_RS08205	COG0705	Rhomboid family
ACZ76_RS08210	COG1349	DNA-binding transcription factor activity
ACZ76_RS08215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACZ76_RS08220	COG0058	SHG alpha-glucan phosphorylase activity
ACZ76_RS08225	COG0297	glycogen (starch) synthase activity
ACZ76_RS08235	COG1523	belongs to the glycosyl hydrolase 13 family
ACZ76_RS08240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACZ76_RS08245	COG3275	phosphorelay sensor kinase activity
ACZ76_RS08265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACZ76_RS08270	COG2095	MarC family integral membrane protein
ACZ76_RS08275	COG3265	gluconokinase activity
ACZ76_RS08280	COG2610	gluconate transmembrane transporter activity
ACZ76_RS08285	COG1609	Transcriptional regulator
ACZ76_RS08290	COG1741	Belongs to the pirin family
ACZ76_RS08295	COG1247	-acetyltransferase
ACZ76_RS08300	COG1082	Xylose isomerase domain protein TIM barrel
ACZ76_RS08305	COG1082	Xylose isomerase domain protein TIM barrel
ACZ76_RS08310	COG0673	inositol 2-dehydrogenase activity
ACZ76_RS08320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ76_RS08330	COG3718	enzyme involved in inositol metabolism
ACZ76_RS08340	COG2814	Major facilitator Superfamily
ACZ76_RS08350	COG2814	Major facilitator Superfamily
ACZ76_RS08355	COG0583	DNA-binding transcription factor activity
ACZ76_RS08405	COG2081	HI0933 family
ACZ76_RS08410	COG0306	phosphate transporter
ACZ76_RS08420	COG0589	response to stress
ACZ76_RS08435	COG0742	ribosomal rna small subunit methyltransferase
ACZ76_RS08445	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACZ76_RS08450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ76_RS08460	COG1295	ribonuclease BN
ACZ76_RS08465	COG2134	cdp-diacylglycerol pyrophosphatase
ACZ76_RS08470	COG2982	Protein involved in outer membrane biogenesis
ACZ76_RS08475	COG2200	EAL domain
ACZ76_RS08480	COG1942	4-Oxalocrotonate Tautomerase
ACZ76_RS08485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ76_RS08490	COG0612	Peptidase, M16
ACZ76_RS08495	COG1301	dicarboxylic acid transport
ACZ76_RS08505	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACZ76_RS08510	COG1561	YicC-like family, N-terminal region
ACZ76_RS08515	COG2423	ornithine cyclodeaminase activity
ACZ76_RS08535	COG3727	T/G mismatch-specific endonuclease activity
ACZ76_RS08545	COG0823	Involved in the tonB-independent uptake of proteins
ACZ76_RS08550	COG5645	(Lipo)protein
ACZ76_RS08565	COG0569	domain protein
ACZ76_RS08565	COG2985	domain, Protein
ACZ76_RS08570	COG3977	Valine--pyruvate aminotransferase
ACZ76_RS08575	COG0366	Alpha amylase catalytic
ACZ76_RS08595	COG2885	chlorophyll binding
ACZ76_RS08605	COG0456	acetyltransferase
ACZ76_RS08610	COG2818	Glycosylase
ACZ76_RS08625	COG0751	glycine-tRNA ligase activity
ACZ76_RS08635	COG2213	PTS system mannitol-specific
ACZ76_RS08635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS08640	COG0246	Mannitol dehydrogenase
ACZ76_RS08645	COG3722	fumarate hydratase activity
ACZ76_RS08655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACZ76_RS08675	COG2258	MOSC domain
ACZ76_RS08680	COG0840	transmembrane signaling receptor activity
ACZ76_RS08685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACZ76_RS08690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACZ76_RS08695	COG3383	formate dehydrogenase (NAD+) activity
ACZ76_RS08695	COG0243	molybdopterin cofactor binding
ACZ76_RS08700	COG3383	formate dehydrogenase (NAD+) activity
ACZ76_RS08700	COG0243	molybdopterin cofactor binding
ACZ76_RS08705	COG0437	4 iron, 4 sulfur cluster binding
ACZ76_RS08710	COG2864	formate dehydrogenase
ACZ76_RS08715	COG3058	Necessary for formate dehydrogenase activity
ACZ76_RS08720	COG1921	L-seryl-tRNASec selenium transferase activity
ACZ76_RS08725	COG3276	selenocysteine insertion sequence binding
ACZ76_RS08730	COG3622	Belongs to the hyi family
ACZ76_RS08735	COG0235	Class ii aldolase
ACZ76_RS08740	COG3395	kinase activity
ACZ76_RS08745	COG1349	DNA-binding transcription factor activity
ACZ76_RS08750	COG2271	Major facilitator Superfamily
ACZ76_RS08755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ76_RS08765	COG3274	enterobacterial common antigen metabolic process
ACZ76_RS08775	COG1335	isochorismatase
ACZ76_RS08785	COG3188	usher protein
ACZ76_RS08790	COG3121	Chaperone
ACZ76_RS08800	COG1070	Carbohydrate kinase
ACZ76_RS08805	COG2115	Belongs to the xylose isomerase family
ACZ76_RS08810	COG4213	ABC transporter substrate-binding protein
ACZ76_RS08820	COG4214	carbohydrate transport
ACZ76_RS08825	COG1609	Transcriptional regulator
ACZ76_RS08825	COG2207	Transcriptional regulator
ACZ76_RS08840	COG0561	phosphatase activity
ACZ76_RS08845	COG0187	DNA topoisomerase II activity
ACZ76_RS08855	COG0592	DNA-directed DNA polymerase activity
ACZ76_RS08860	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACZ76_RS08865	COG0594	ribonuclease P activity
ACZ76_RS08870	COG0706	membrane insertase activity
ACZ76_RS08875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACZ76_RS08880	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ACZ76_RS08890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACZ76_RS08895	COG2011	ABC-type metal ion transport system permease component
ACZ76_RS08900	COG0840	transmembrane signaling receptor activity
ACZ76_RS08905	COG0431	NADPH-dependent FMN reductase
ACZ76_RS08910	COG4191	Histidine kinase
ACZ76_RS08925	COG2252	PERMEase
ACZ76_RS08930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACZ76_RS08935	COG0765	amino acid transport
ACZ76_RS08940	COG0765	amino acid transport
ACZ76_RS08945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS08955	COG0704	Plays a role in the regulation of phosphate uptake
ACZ76_RS08965	COG0581	inorganic phosphate transmembrane transporter activity
ACZ76_RS08970	COG0573	inorganic phosphate transmembrane transporter activity
ACZ76_RS08975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACZ76_RS08985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACZ76_RS08990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACZ76_RS08995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACZ76_RS09005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACZ76_RS09010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACZ76_RS09015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACZ76_RS09025	COG0356	it plays a direct role in the translocation of protons across the membrane
ACZ76_RS09030	COG3312	ion transport
ACZ76_RS09035	COG0357	Ribosomal RNA small subunit methyltransferase G
ACZ76_RS09040	COG0445	tRNA wobble uridine modification
ACZ76_RS09045	COG0716	FMN binding
ACZ76_RS09050	COG1522	sequence-specific DNA binding
ACZ76_RS09055	COG2502	aspartate--ammonia ligase
ACZ76_RS09065	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ACZ76_RS09070	COG0714	Associated with various cellular activities
ACZ76_RS09075	COG3158	transport of potassium into the cell
ACZ76_RS09080	COG1869	D-ribose catabolic process
ACZ76_RS09085	COG1129	ABC transporter
ACZ76_RS09090	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS09095	COG1879	ABC-type sugar transport system periplasmic component
ACZ76_RS09100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ76_RS09105	COG1609	Transcriptional regulator
ACZ76_RS09110	COG0477	Major facilitator Superfamily
ACZ76_RS09115	COG2186	Transcriptional regulator
ACZ76_RS09140	COG1763	Mo-molybdopterin cofactor biosynthetic process
ACZ76_RS09150	COG3084	Protein conserved in bacteria
ACZ76_RS09155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACZ76_RS09160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACZ76_RS09165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACZ76_RS09165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACZ76_RS09170	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACZ76_RS09175	COG3078	GTPase activator activity
ACZ76_RS09180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACZ76_RS09190	COG3852	Histidine kinase
ACZ76_RS09205	COG1011	Hydrolase
ACZ76_RS09210	COG1295	ribonuclease BN
ACZ76_RS09215	COG1490	D-aminoacyl-tRNA deacylase activity
ACZ76_RS09220	COG0456	acetyltransferase
ACZ76_RS09235	COG2204	response regulator
ACZ76_RS09250	COG3423	Transcriptional regulator
ACZ76_RS09275	COG2982	Protein involved in outer membrane biogenesis
ACZ76_RS09280	COG2233	PERMEase
ACZ76_RS09285	COG0786	glutamate:sodium symporter activity
ACZ76_RS09290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACZ76_RS09295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACZ76_RS09300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACZ76_RS09305	COG1758	RNA polymerase activity
ACZ76_RS09315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACZ76_RS09320	COG2860	membrane
ACZ76_RS09330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACZ76_RS09335	COG1024	Enoyl-CoA hydratase
ACZ76_RS09340	COG5001	Diguanylate cyclase
ACZ76_RS09345	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACZ76_RS09350	COG2986	histidine ammonia-lyase
ACZ76_RS09365	COG1764	response to oxidative stress
ACZ76_RS09370	COG2194	sulfuric ester hydrolase activity
ACZ76_RS09375	COG2197	response regulator
ACZ76_RS09380	COG3851	Histidine kinase
ACZ76_RS09385	COG2271	Major facilitator Superfamily
ACZ76_RS09395	COG2831	hemolysin activation secretion protein
ACZ76_RS09400	COG3210	domain, Protein
ACZ76_RS09405	COG0747	negative chemotaxis
ACZ76_RS09410	COG0601	transmembrane transport
ACZ76_RS09415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACZ76_RS09420	COG0444	Belongs to the ABC transporter superfamily
ACZ76_RS09425	COG4608	Belongs to the ABC transporter superfamily
ACZ76_RS09430	COG2194	sulfuric ester hydrolase activity
ACZ76_RS09450	COG1192	Involved in chromosome partitioning
ACZ76_RS09460	COG1215	transferase activity, transferring glycosyl groups
ACZ76_RS09470	COG0457	Tetratricopeptide repeat
ACZ76_RS09470	COG3118	belongs to the thioredoxin family
ACZ76_RS09475	COG2199	diguanylate cyclase activity
ACZ76_RS09475	COG2200	EAL domain
ACZ76_RS09480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACZ76_RS09490	COG1309	transcriptional regulator
ACZ76_RS09495	COG0756	dUTP diphosphatase activity
ACZ76_RS09500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACZ76_RS09510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACZ76_RS09515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACZ76_RS09535	COG1519	Transferase
ACZ76_RS09540	COG0859	PFAM glycosyl transferase family 9
ACZ76_RS09545	COG0859	PFAM glycosyl transferase family 9
ACZ76_RS09550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ76_RS09555	COG0156	8-amino-7-oxononanoate synthase activity
ACZ76_RS09565	COG2861	carbohydrate metabolic process
ACZ76_RS09570	COG4942	peptidase
ACZ76_RS09575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACZ76_RS09580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACZ76_RS09585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACZ76_RS09590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ACZ76_RS09595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ACZ76_RS09605	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACZ76_RS09610	COG2169	Transcriptional regulator
ACZ76_RS09610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACZ76_RS09615	COG2205	protein histidine kinase activity
ACZ76_RS09620	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS09625	COG3678	ATP-independent chaperone mediated protein folding
ACZ76_RS09630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACZ76_RS09640	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACZ76_RS09660	COG3152	Membrane
ACZ76_RS09670	COG0527	aspartate kinase activity
ACZ76_RS09670	COG0460	homoserine dehydrogenase
ACZ76_RS09675	COG0626	cystathionine gamma-synthase activity
ACZ76_RS09680	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ACZ76_RS09685	COG0254	rRNA binding
ACZ76_RS09690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACZ76_RS09695	COG1609	Transcriptional regulator
ACZ76_RS09700	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACZ76_RS09705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACZ76_RS09710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACZ76_RS09715	COG1575	Belongs to the MenA family. Type 1 subfamily
ACZ76_RS09720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACZ76_RS09725	COG3074	FtsZ-dependent cytokinesis
ACZ76_RS09730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACZ76_RS09735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACZ76_RS09740	COG1494	fructose-1,6-bisphosphatase
ACZ76_RS09745	COG2814	Major facilitator Superfamily
ACZ76_RS09755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACZ76_RS09770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACZ76_RS09775	COG0165	Argininosuccinate lyase
ACZ76_RS09810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ76_RS09815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACZ76_RS09815	COG0678	peroxiredoxin activity
ACZ76_RS09825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ76_RS09830	COG1309	transcriptional regulator
ACZ76_RS09840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACZ76_RS09850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACZ76_RS09890	COG1879	ABC-type sugar transport system periplasmic component
ACZ76_RS09895	COG1129	ABC transporter
ACZ76_RS09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS09905	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS09910	COG0583	DNA-binding transcription factor activity
ACZ76_RS09915	COG3085	chromosome segregation
ACZ76_RS09930	COG3978	acetolactate synthase activity
ACZ76_RS09935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACZ76_RS09940	COG0129	dihydroxy-acid dehydratase activity
ACZ76_RS09945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACZ76_RS09960	COG0583	DNA-binding transcription factor activity
ACZ76_RS09965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACZ76_RS10000	COG3121	Chaperone
ACZ76_RS10015	COG3121	Chaperone
ACZ76_RS10025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACZ76_RS10040	COG0248	Ppx GppA phosphatase
ACZ76_RS10050	COG3118	belongs to the thioredoxin family
ACZ76_RS10055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACZ76_RS10060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACZ76_RS10065	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ACZ76_RS10070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACZ76_RS10075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACZ76_RS10080	COG1088	dTDP-glucose 4,6-dehydratase activity
ACZ76_RS10085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACZ76_RS10090	COG0456	acetyltransferase
ACZ76_RS10095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACZ76_RS10100	COG2244	polysaccharide biosynthetic process
ACZ76_RS10105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACZ76_RS10145	COG3071	HemY protein
ACZ76_RS10150	COG2959	enzyme of heme biosynthesis
ACZ76_RS10155	COG1587	Uroporphyrinogen-III synthase
ACZ76_RS10160	COG0181	hydroxymethylbilane synthase activity
ACZ76_RS10165	COG3072	Adenylate cyclase
ACZ76_RS10170	COG1965	Belongs to the frataxin family
ACZ76_RS10175	COG5567	small periplasmic lipoprotein
ACZ76_RS10180	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACZ76_RS10185	COG3159	Protein conserved in bacteria
ACZ76_RS10190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACZ76_RS10195	COG1011	Hydrolase
ACZ76_RS10200	COG0210	DNA helicase
ACZ76_RS10210	COG5441	Belongs to the UPF0261 family
ACZ76_RS10215	COG5564	TIM-barrel signal transduction protein
ACZ76_RS10235	COG2050	protein possibly involved in aromatic compounds catabolism
ACZ76_RS10240	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ACZ76_RS10250	COG1280	lysine exporter protein (LysE YggA)
ACZ76_RS10260	COG2267	carboxylic ester hydrolase activity
ACZ76_RS10265	COG0561	phosphatase activity
ACZ76_RS10270	COG0584	glycerophosphoryl diester phosphodiesterase
ACZ76_RS10275	COG2271	Major facilitator Superfamily
ACZ76_RS10280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACZ76_RS10290	COG0247	lactate metabolic process
ACZ76_RS10300	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACZ76_RS10305	COG0425	Belongs to the sulfur carrier protein TusA family
ACZ76_RS10315	COG3714	YhhN family
ACZ76_RS10330	COG3776	membrane
ACZ76_RS10335	COG0742	ribosomal rna small subunit methyltransferase
ACZ76_RS10340	COG0552	protein localization to endoplasmic reticulum
ACZ76_RS10340	COG0552	protein localization to endoplasmic reticulum
ACZ76_RS10345	COG2884	Cell division ATP-binding protein ftsE
ACZ76_RS10350	COG2177	Part of the ABC transporter FtsEX involved in
ACZ76_RS10360	COG0456	acetyltransferase
ACZ76_RS10365	COG0683	leucine binding
ACZ76_RS10375	COG4177	L-phenylalanine transmembrane transporter activity
ACZ76_RS10385	COG0410	ABC transporter
ACZ76_RS10430	COG1653	transport
ACZ76_RS10435	COG1175	transmembrane transport
ACZ76_RS10440	COG0395	ABC-type sugar transport system, permease component
ACZ76_RS10445	COG3842	ATPase activity
ACZ76_RS10450	COG0584	glycerophosphoryl diester phosphodiesterase
ACZ76_RS10455	COG0679	Auxin Efflux Carrier
ACZ76_RS10465	COG0697	spore germination
ACZ76_RS10470	COG0583	DNA-binding transcription factor activity
ACZ76_RS10475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACZ76_RS10480	COG0412	Dienelactone hydrolase
ACZ76_RS10495	COG1966	Carbon starvation protein
ACZ76_RS10500	COG0586	Pfam SNARE associated Golgi protein
ACZ76_RS10505	COG1322	Protein conserved in bacteria
ACZ76_RS10510	COG2226	methyltransferase
ACZ76_RS10520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACZ76_RS10525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACZ76_RS10530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACZ76_RS10535	COG0805	protein transport
ACZ76_RS10555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACZ76_RS10560	COG0543	2 iron, 2 sulfur cluster binding
ACZ76_RS10565	COG0183	Belongs to the thiolase family
ACZ76_RS10570	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACZ76_RS10570	COG1024	Enoyl-CoA hydratase
ACZ76_RS10580	COG1739	Uncharacterized protein family UPF0029
ACZ76_RS10585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACZ76_RS10625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACZ76_RS10630	COG3162	membrane
ACZ76_RS10635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACZ76_RS10640	COG1301	dicarboxylic acid transport
ACZ76_RS10650	COG2205	protein histidine kinase activity
ACZ76_RS10650	COG5002	protein histidine kinase activity
ACZ76_RS10650	COG0784	Response regulator, receiver
ACZ76_RS10810	COG1196	nuclear chromosome segregation
ACZ76_RS10810	COG3264	Mechanosensitive ion channel
ACZ76_RS10815	COG4774	siderophore transport
ACZ76_RS10825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACZ76_RS10830	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ACZ76_RS10835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACZ76_RS10840	COG4558	Periplasmic binding protein
ACZ76_RS10845	COG3720	iron ion transport
ACZ76_RS10860	COG0702	epimerase
ACZ76_RS10865	COG3721	Heme iron utilization protein
ACZ76_RS10875	COG1215	transferase activity, transferring glycosyl groups
ACZ76_RS10890	COG0463	Glycosyl transferase, family 2
ACZ76_RS10920	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACZ76_RS10925	COG0543	2 iron, 2 sulfur cluster binding
ACZ76_RS10925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACZ76_RS10935	COG2826	transposase and inactivated derivatives, IS30 family
ACZ76_RS10950	COG1309	transcriptional regulator
ACZ76_RS10960	COG2084	Dehydrogenase
ACZ76_RS10965	COG1929	Belongs to the glycerate kinase type-1 family
ACZ76_RS10970	COG3835	regulator
ACZ76_RS10975	COG2721	sulfolactate sulfo-lyase activity
ACZ76_RS10980	COG2271	Major facilitator Superfamily
ACZ76_RS10985	COG0493	'glutamate synthase
ACZ76_RS10985	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACZ76_RS10990	COG4232	protein-disulfide reductase activity
ACZ76_RS11015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACZ76_RS11020	COG0459	protein refolding
ACZ76_RS11055	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ACZ76_RS11060	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ACZ76_RS11065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACZ76_RS11070	COG1053	succinate dehydrogenase
ACZ76_RS11075	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACZ76_RS11080	COG3264	Mechanosensitive ion channel
ACZ76_RS11080	COG1511	domain protein
ACZ76_RS11085	COG0688	phosphatidylethanolamine metabolic process
ACZ76_RS11090	COG1162	GTPase activity
ACZ76_RS11095	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACZ76_RS11115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACZ76_RS11120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACZ76_RS11120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACZ76_RS11125	COG0802	atpase or kinase
ACZ76_RS11130	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACZ76_RS11135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACZ76_RS11145	COG1923	regulation of RNA biosynthetic process
ACZ76_RS11150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACZ76_RS11155	COG0330	HflC and HflK could
ACZ76_RS11160	COG0330	HflC and HflK could
ACZ76_RS11165	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ACZ76_RS11170	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACZ76_RS11175	COG1959	2 iron, 2 sulfur cluster binding
ACZ76_RS11180	COG0557	exoribonuclease II activity
ACZ76_RS11185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACZ76_RS11190	COG1960	acyl-CoA dehydrogenase activity
ACZ76_RS11195	COG3650	response to hydrogen peroxide
ACZ76_RS11200	COG1073	alpha beta
ACZ76_RS11210	COG0360	Binds together with S18 to 16S ribosomal RNA
ACZ76_RS11220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACZ76_RS11235	COG3061	Opacity-associated protein A
ACZ76_RS11240	COG0545	Peptidyl-prolyl cis-trans isomerase
ACZ76_RS11250	COG0737	Belongs to the 5'-nucleotidase family
ACZ76_RS11255	COG1218	3'(2'),5'-bisphosphate nucleotidase
ACZ76_RS11260	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ACZ76_RS11270	COG1253	flavin adenine dinucleotide binding
ACZ76_RS11275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACZ76_RS11285	COG2911	Protein conserved in bacteria
ACZ76_RS11290	COG2105	PFAM AIG2 family protein
ACZ76_RS11315	COG0438	transferase activity, transferring glycosyl groups
ACZ76_RS11335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACZ76_RS11345	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACZ76_RS11350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACZ76_RS11370	COG3423	Transcriptional regulator
ACZ76_RS11380	COG0142	geranyltranstransferase activity
ACZ76_RS11395	COG0697	spore germination
ACZ76_RS11405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACZ76_RS11410	COG0642	Histidine kinase
ACZ76_RS11415	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS11420	COG2027	D-alanyl-D-alanine carboxypeptidase
ACZ76_RS11430	COG1534	Rna-binding protein
ACZ76_RS11435	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACZ76_RS11445	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACZ76_RS11455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACZ76_RS11475	COG0195	Participates in both transcription termination and antitermination
ACZ76_RS11485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACZ76_RS11490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACZ76_RS11500	COG1185	polyribonucleotide nucleotidyltransferase activity
ACZ76_RS11510	COG0513	Belongs to the DEAD box helicase family
ACZ76_RS11520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACZ76_RS11530	COG0814	amino acid
ACZ76_RS11535	COG3681	Belongs to the UPF0597 family
ACZ76_RS11540	COG0826	peptidase U32
ACZ76_RS11545	COG0826	peptidase U32
ACZ76_RS11550	COG3154	lipid carrier protein
ACZ76_RS11555	COG3153	acetyltransferase
ACZ76_RS11560	COG2827	Endonuclease containing a URI domain
ACZ76_RS11565	COG0531	amino acid
ACZ76_RS11570	COG1982	Orn Lys Arg decarboxylase major
ACZ76_RS11585	COG1653	transport
ACZ76_RS11590	COG1175	transmembrane transport
ACZ76_RS11595	COG0395	ABC-type sugar transport system, permease component
ACZ76_RS11600	COG3842	ATPase activity
ACZ76_RS11610	COG3787	Belongs to the UPF0306 family
ACZ76_RS11615	COG0702	epimerase
ACZ76_RS11620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACZ76_RS11625	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ACZ76_RS11630	COG3454	Phosphonate metabolism
ACZ76_RS11635	COG4778	phosphonate C-P lyase system protein PhnL
ACZ76_RS11640	COG4107	phosphonate C-P lyase system protein PhnK
ACZ76_RS11645	COG3627	carbon phosphorus lyase activity
ACZ76_RS11650	COG3626	phosphonate metabolism
ACZ76_RS11655	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ACZ76_RS11660	COG3624	Phosphonate C-P lyase system protein PhnG
ACZ76_RS11665	COG2188	Transcriptional regulator
ACZ76_RS11680	COG0602	queuosine metabolic process
ACZ76_RS11700	COG4608	Belongs to the ABC transporter superfamily
ACZ76_RS11705	COG0444	Belongs to the ABC transporter superfamily
ACZ76_RS11710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACZ76_RS11715	COG0601	transmembrane transport
ACZ76_RS11725	COG2731	YhcH YjgK YiaL family protein
ACZ76_RS11735	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ACZ76_RS11750	COG2927	DNA polymerase III (CHI subunit)
ACZ76_RS11755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACZ76_RS11760	COG0795	lipopolysaccharide-transporting ATPase activity
ACZ76_RS11765	COG0795	lipopolysaccharide-transporting ATPase activity
ACZ76_RS11775	COG2963	transposase activity
ACZ76_RS11780	COG2826	transposase and inactivated derivatives, IS30 family
ACZ76_RS11805	COG3423	Transcriptional regulator
ACZ76_RS11830	COG1879	ABC-type sugar transport system periplasmic component
ACZ76_RS11835	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS11840	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS11845	COG1129	ABC transporter
ACZ76_RS11850	COG2390	Transcriptional regulator
ACZ76_RS11855	COG1070	Carbohydrate kinase
ACZ76_RS11860	COG0859	PFAM glycosyl transferase family 9
ACZ76_RS11875	COG2235	arginine
ACZ76_RS11880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS11885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ76_RS11895	COG2376	Dihydroxyacetone kinase
ACZ76_RS11900	COG1461	Dihydroxyacetone kinase
ACZ76_RS11905	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ACZ76_RS11905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS11905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACZ76_RS11915	COG2192	nodulation
ACZ76_RS11950	COG4772	TonB-dependent receptor
ACZ76_RS11985	COG0667	Aldo Keto reductase
ACZ76_RS11990	COG2813	Specifically methylates the guanine in position
ACZ76_RS11995	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ACZ76_RS12005	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACZ76_RS12010	COG2823	Periplasmic or secreted lipoprotein
ACZ76_RS12015	COG4667	esterase of the alpha-beta hydrolase superfamily
ACZ76_RS12020	COG0084	hydrolase, TatD family'
ACZ76_RS12025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACZ76_RS12040	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ACZ76_RS12050	COG3550	peptidyl-serine autophosphorylation
ACZ76_RS12055	COG3726	membrane protein affecting hemolysin expression
ACZ76_RS12060	COG0560	Phosphoserine phosphatase
ACZ76_RS12075	COG0604	alcohol dehydrogenase
ACZ76_RS12080	COG0583	DNA-binding transcription factor activity
ACZ76_RS12090	COG0488	(ABC) transporter
ACZ76_RS12095	COG2885	chlorophyll binding
ACZ76_RS12100	COG2199	diguanylate cyclase activity
ACZ76_RS12110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACZ76_RS12115	COG0741	lytic transglycosylase activity
ACZ76_RS12120	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ACZ76_RS12125	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ACZ76_RS12135	COG3708	Transcriptional regulator
ACZ76_RS12135	COG2207	Transcriptional regulator
ACZ76_RS12140	COG3045	CreA protein
ACZ76_RS12145	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS12150	COG2826	transposase and inactivated derivatives, IS30 family
ACZ76_RS12160	COG0083	homoserine kinase activity
ACZ76_RS12170	COG3022	response to hydroperoxide
ACZ76_RS12175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACZ76_RS12180	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACZ76_RS12185	COG0477	Major facilitator Superfamily
ACZ76_RS12195	COG1584	GPR1 FUN34 yaaH family protein
ACZ76_RS12205	COG0484	heat shock protein binding
ACZ76_RS12210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACZ76_RS12215	COG0583	DNA-binding transcription factor activity
ACZ76_RS12225	COG0196	riboflavin kinase activity
ACZ76_RS12230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACZ76_RS12235	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACZ76_RS12240	COG1047	Peptidyl-prolyl cis-trans
ACZ76_RS12245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACZ76_RS12250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACZ76_RS12260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACZ76_RS12265	COG1280	lysine exporter protein (LysE YggA)
ACZ76_RS12270	COG2966	Psort location CytoplasmicMembrane, score
ACZ76_RS12280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACZ76_RS12285	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACZ76_RS12290	COG2967	ApaG domain
ACZ76_RS12295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACZ76_RS12310	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ACZ76_RS12315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ACZ76_RS12325	COG0564	pseudouridine synthase activity
ACZ76_RS12335	COG0417	DNA replication proofreading
ACZ76_RS12340	COG0586	Pfam SNARE associated Golgi protein
ACZ76_RS12350	COG1178	ABC-type Fe3 transport system permease component
ACZ76_RS12355	COG4143	(ABC) transporter
ACZ76_RS12360	COG4533	DNA binding
ACZ76_RS12365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACZ76_RS12370	COG1882	Formate acetyltransferase
ACZ76_RS12375	COG2814	Major facilitator Superfamily
ACZ76_RS12385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACZ76_RS12390	COG0473	3-isopropylmalate dehydrogenase activity
ACZ76_RS12405	COG1022	Amp-dependent synthetase and ligase
ACZ76_RS12410	COG0028	Belongs to the TPP enzyme family
ACZ76_RS12435	COG0275	rRNA processing
ACZ76_RS12440	COG3116	cell division
ACZ76_RS12445	COG0768	penicillin binding
ACZ76_RS12450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACZ76_RS12455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACZ76_RS12460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACZ76_RS12470	COG0772	Belongs to the SEDS family
ACZ76_RS12475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACZ76_RS12480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACZ76_RS12490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACZ76_RS12495	COG0849	cell division
ACZ76_RS12500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACZ76_RS12520	COG0653	protein targeting
ACZ76_RS12525	COG0494	nUDIX hydrolase
ACZ76_RS12530	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACZ76_RS12545	COG0516	GMP reductase activity
ACZ76_RS12550	COG1459	type II secretion system
ACZ76_RS12555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACZ76_RS12560	COG4969	Belongs to the N-Me-Phe pilin family
ACZ76_RS12570	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACZ76_RS12575	COG3725	Membrane protein required for beta-lactamase induction
ACZ76_RS12580	COG3940	Belongs to the glycosyl hydrolase 43 family
ACZ76_RS12585	COG2211	Major facilitator Superfamily
ACZ76_RS12590	COG1113	amino acid transport
ACZ76_RS12595	COG2186	Transcriptional regulator
ACZ76_RS12600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ACZ76_RS12605	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACZ76_RS12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACZ76_RS12620	COG2207	Transcriptional regulator
ACZ76_RS12635	COG3112	Uncharacterised protein family (UPF0231)
ACZ76_RS12640	COG0697	spore germination
ACZ76_RS12670	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACZ76_RS12680	COG2132	Multicopper oxidase
ACZ76_RS12690	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ACZ76_RS12695	COG0288	reversible hydration of carbon dioxide
ACZ76_RS12700	COG1131	(ABC) transporter
ACZ76_RS12705	COG0842	Transport permease protein
ACZ76_RS12710	COG0726	polysaccharide deacetylase
ACZ76_RS12715	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACZ76_RS12720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACZ76_RS12725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACZ76_RS12730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACZ76_RS12735	COG0617	tRNA 3'-terminal CCA addition
ACZ76_RS12750	COG1489	DNA binding
ACZ76_RS12755	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ACZ76_RS12760	COG1643	Atp-dependent helicase
ACZ76_RS12765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACZ76_RS12770	COG1120	ATPase activity
ACZ76_RS12775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACZ76_RS12780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACZ76_RS12790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACZ76_RS12800	COG0316	Belongs to the HesB IscA family
ACZ76_RS12810	COG2860	membrane
ACZ76_RS12820	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACZ76_RS12825	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ACZ76_RS12830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACZ76_RS12840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACZ76_RS12845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACZ76_RS12850	COG3956	TIGRFAM MazG family protein
ACZ76_RS12855	COG0504	CTP synthase activity
ACZ76_RS12860	COG0148	phosphopyruvate hydratase activity
ACZ76_RS12870	COG0602	queuosine metabolic process
ACZ76_RS12875	COG0720	synthase
ACZ76_RS12880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACZ76_RS12885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACZ76_RS12890	COG0175	sulfate reduction
ACZ76_RS12900	COG2234	aminopeptidase activity
ACZ76_RS12905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACZ76_RS12905	COG1648	precorrin-2 dehydrogenase activity
ACZ76_RS12910	COG0175	sulfate reduction
ACZ76_RS12915	COG2895	sulfate adenylyltransferase (ATP) activity
ACZ76_RS12920	COG0529	Catalyzes the synthesis of activated sulfate
ACZ76_RS12930	COG0698	ribose 5-phosphate isomerase
ACZ76_RS12935	COG1063	alcohol dehydrogenase
ACZ76_RS12940	COG2814	Major facilitator Superfamily
ACZ76_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS12950	COG2376	Dihydroxyacetone kinase
ACZ76_RS12955	COG1461	Dihydroxyacetone kinase
ACZ76_RS12960	COG2390	Transcriptional regulator
ACZ76_RS12970	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACZ76_RS12980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ACZ76_RS12985	COG0585	pseudouridine synthase activity
ACZ76_RS12990	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACZ76_RS12995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACZ76_RS13000	COG1388	LysM domain
ACZ76_RS13000	COG4942	peptidase
ACZ76_RS13005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACZ76_RS13010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACZ76_RS13035	COG3188	usher protein
ACZ76_RS13040	COG3121	Chaperone
ACZ76_RS13050	COG3539	Fimbrial protein
ACZ76_RS13085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS13095	COG1538	Outer membrane efflux protein
ACZ76_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS13120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS13125	COG4948	Mandelate Racemase Muconate Lactonizing
ACZ76_RS13135	COG0601	transmembrane transport
ACZ76_RS13140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACZ76_RS13145	COG0444	Belongs to the ABC transporter superfamily
ACZ76_RS13150	COG4608	Belongs to the ABC transporter superfamily
ACZ76_RS13155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS13160	COG0765	amino acid transport
ACZ76_RS13165	COG0765	amino acid transport
ACZ76_RS13170	COG1126	abc transporter atp-binding protein
ACZ76_RS13175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACZ76_RS13190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACZ76_RS13195	COG0640	Transcriptional regulator
ACZ76_RS13210	COG0277	FAD linked oxidase domain protein
ACZ76_RS13215	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACZ76_RS13215	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACZ76_RS13220	COG1349	DNA-binding transcription factor activity
ACZ76_RS13230	COG1070	Carbohydrate kinase
ACZ76_RS13240	COG0738	Major facilitator superfamily
ACZ76_RS13245	COG0235	Class ii aldolase
ACZ76_RS13250	COG1454	alcohol dehydrogenase
ACZ76_RS13255	COG0243	molybdopterin cofactor binding
ACZ76_RS13260	COG0437	4 iron, 4 sulfur cluster binding
ACZ76_RS13265	COG3302	dmso reductase anchor subunit
ACZ76_RS13270	COG3381	protein complex oligomerization
ACZ76_RS13285	COG1879	ABC-type sugar transport system periplasmic component
ACZ76_RS13295	COG1129	ABC transporter
ACZ76_RS13300	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS13305	COG3959	Transketolase, thiamine diphosphate binding domain
ACZ76_RS13310	COG3958	Transketolase
ACZ76_RS13315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACZ76_RS13340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACZ76_RS13345	COG2137	regulation of response to DNA damage stimulus
ACZ76_RS13350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACZ76_RS13355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACZ76_RS13380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACZ76_RS13385	COG1238	metal cluster binding
ACZ76_RS13390	COG2918	glutathione biosynthetic process
ACZ76_RS13395	COG1854	S-ribosylhomocysteine lyase activity
ACZ76_RS13400	COG4536	flavin adenine dinucleotide binding
ACZ76_RS13405	COG4137	Cytochrome C assembly protein
ACZ76_RS13410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACZ76_RS13420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACZ76_RS13430	COG0335	large ribosomal subunit rRNA binding
ACZ76_RS13435	COG3137	Salt-induced outer membrane protein
ACZ76_RS13440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ACZ76_RS13445	COG3279	Response regulator of the LytR AlgR family
ACZ76_RS13450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACZ76_RS13455	COG1605	Chorismate mutase
ACZ76_RS13455	COG0287	Prephenate dehydrogenase
ACZ76_RS13460	COG1605	Chorismate mutase
ACZ76_RS13460	COG0077	Prephenate dehydratase
ACZ76_RS13465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACZ76_RS13470	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACZ76_RS13475	COG0564	pseudouridine synthase activity
ACZ76_RS13485	COG0542	response to heat
ACZ76_RS13520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACZ76_RS13525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACZ76_RS13525	COG1042	CoA-binding domain protein
ACZ76_RS13525	COG0045	succinate-CoA ligase (ADP-forming) activity
ACZ76_RS13530	COG3148	PFAM DTW domain containing protein
ACZ76_RS13535	COG3118	belongs to the thioredoxin family
ACZ76_RS13540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACZ76_RS13545	COG2814	Major facilitator Superfamily
ACZ76_RS13550	COG1566	PFAM secretion protein HlyD family protein
ACZ76_RS13555	COG1538	Outer membrane efflux protein
ACZ76_RS13560	COG1846	Transcriptional regulator
ACZ76_RS13570	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACZ76_RS13575	COG2814	Major facilitator Superfamily
ACZ76_RS13580	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACZ76_RS13590	COG0436	Aminotransferase
ACZ76_RS13595	COG0235	Class ii aldolase
ACZ76_RS13605	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACZ76_RS13615	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ACZ76_RS13630	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ACZ76_RS13635	COG1960	acyl-CoA dehydrogenase activity
ACZ76_RS13645	COG0121	glutamine amidotransferase
ACZ76_RS13650	COG3034	peptidoglycan biosynthetic process
ACZ76_RS13660	COG1805	sodium ion transport
ACZ76_RS13665	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ76_RS13670	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ76_RS13675	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ACZ76_RS13680	COG2871	sodium ion transport
ACZ76_RS13685	COG1477	protein flavinylation
ACZ76_RS13690	COG2991	Protein conserved in bacteria
ACZ76_RS13700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACZ76_RS13705	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACZ76_RS13715	COG1073	alpha beta
ACZ76_RS13725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACZ76_RS13730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACZ76_RS13750	COG2226	methyltransferase
ACZ76_RS13775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACZ76_RS13780	COG3123	guanosine phosphorylase activity
ACZ76_RS13785	COG2974	May be involved in recombination
ACZ76_RS13790	COG1940	carbohydrate kinase activity
ACZ76_RS13795	COG0419	ATPase involved in DNA repair
ACZ76_RS13800	COG0420	3'-5' exonuclease activity
ACZ76_RS13805	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS13810	COG5002	protein histidine kinase activity
ACZ76_RS13825	COG1113	amino acid transport
ACZ76_RS13830	COG0366	Alpha amylase catalytic
ACZ76_RS13845	COG0450	alkyl hydroperoxide reductase
ACZ76_RS13850	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ACZ76_RS13860	COG0343	queuine tRNA-ribosyltransferase activity
ACZ76_RS13865	COG1862	Preprotein translocase
ACZ76_RS13870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACZ76_RS13875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACZ76_RS13890	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACZ76_RS13895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACZ76_RS13895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACZ76_RS13900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACZ76_RS13910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACZ76_RS13915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACZ76_RS13920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACZ76_RS13925	COG0142	geranyltranstransferase activity
ACZ76_RS13930	COG1722	exodeoxyribonuclease VII activity
ACZ76_RS13935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACZ76_RS13935	COG0301	tRNA thio-modification
ACZ76_RS13940	COG0693	protein deglycase activity
ACZ76_RS13945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACZ76_RS13950	COG1666	GTP binding
ACZ76_RS13955	COG2814	Major facilitator Superfamily
ACZ76_RS13960	COG0109	protoheme IX farnesyltransferase activity
ACZ76_RS13965	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACZ76_RS13970	COG1845	cytochrome c oxidase, subunit III
ACZ76_RS13975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACZ76_RS13980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACZ76_RS13990	COG2223	nitrite transmembrane transporter activity
ACZ76_RS13995	COG3056	Lipoprotein
ACZ76_RS14000	COG0271	Belongs to the BolA IbaG family
ACZ76_RS14005	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACZ76_RS14010	COG0740	serine-type endopeptidase activity
ACZ76_RS14015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACZ76_RS14020	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACZ76_RS14025	COG0776	regulation of translation
ACZ76_RS14030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACZ76_RS14035	COG1555	photosystem II stabilization
ACZ76_RS14040	COG0824	Thioesterase
ACZ76_RS14045	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACZ76_RS14050	COG4533	DNA binding
ACZ76_RS14055	COG0561	phosphatase activity
ACZ76_RS14065	COG1522	sequence-specific DNA binding
ACZ76_RS14070	COG1132	(ABC) transporter
ACZ76_RS14075	COG1132	(ABC) transporter
ACZ76_RS14080	COG0347	Belongs to the P(II) protein family
ACZ76_RS14085	COG0004	ammonium transporteR
ACZ76_RS14090	COG1946	Acyl-CoA thioesterase
ACZ76_RS14095	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ACZ76_RS14100	COG3695	enzyme binding
ACZ76_RS14120	COG1121	(ABC) transporter
ACZ76_RS14125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACZ76_RS14130	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACZ76_RS14135	COG0254	rRNA binding
ACZ76_RS14150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ACZ76_RS14155	COG3457	Alanine racemase
ACZ76_RS14165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACZ76_RS14170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS14175	COG1309	transcriptional regulator
ACZ76_RS14180	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACZ76_RS14185	COG1196	nuclear chromosome segregation
ACZ76_RS14185	COG3264	Mechanosensitive ion channel
ACZ76_RS14195	COG2832	Protein of unknown function (DUF454)
ACZ76_RS14200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACZ76_RS14215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACZ76_RS14220	COG0326	Molecular chaperone. Has ATPase activity
ACZ76_RS14225	COG0563	adenylate kinase activity
ACZ76_RS14230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ACZ76_RS14250	COG2963	transposase activity
ACZ76_RS14285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ76_RS14300	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ACZ76_RS14305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACZ76_RS14310	COG4651	solute:proton antiporter activity
ACZ76_RS14310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACZ76_RS14315	COG2223	nitrite transmembrane transporter activity
ACZ76_RS14320	COG0737	Belongs to the 5'-nucleotidase family
ACZ76_RS14325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACZ76_RS14330	COG3735	TraB family
ACZ76_RS14335	COG2217	Heavy metal translocating P-type atpase
ACZ76_RS14340	COG0789	Transcriptional regulator
ACZ76_RS14345	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACZ76_RS14350	COG0330	HflC and HflK could
ACZ76_RS14355	COG3118	belongs to the thioredoxin family
ACZ76_RS14360	COG0300	oxidoreductase activity
ACZ76_RS14365	COG2755	lipolytic protein G-D-S-L family
ACZ76_RS14370	COG4181	ATPase activity
ACZ76_RS14375	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACZ76_RS14380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACZ76_RS14385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACZ76_RS14390	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACZ76_RS14395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACZ76_RS14400	COG0215	cysteine-tRNA ligase activity
ACZ76_RS14405	COG2501	S4 domain
ACZ76_RS14410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACZ76_RS14420	COG3210	domain, Protein
ACZ76_RS14440	COG5444	nuclease activity
ACZ76_RS14450	COG3210	domain, Protein
ACZ76_RS14460	COG2801	Transposase and inactivated derivatives
ACZ76_RS14470	COG3210	domain, Protein
ACZ76_RS14475	COG2831	hemolysin activation secretion protein
ACZ76_RS14480	COG2140	Oxalate decarboxylase
ACZ76_RS14490	COG3716	PTS system mannose fructose sorbose family IID component
ACZ76_RS14495	COG3715	PTS system
ACZ76_RS14500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS14500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS14515	COG1609	Transcriptional regulator
ACZ76_RS14525	COG2850	peptidyl-arginine hydroxylation
ACZ76_RS14530	COG5265	(ABC) transporter
ACZ76_RS14545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACZ76_RS14555	COG2197	response regulator
ACZ76_RS14560	COG1278	Cold shock
ACZ76_RS14575	COG3706	GGDEF domain
ACZ76_RS14580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACZ76_RS14585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACZ76_RS14590	COG0321	lipoyl(octanoyl) transferase activity
ACZ76_RS14595	COG2921	Belongs to the UPF0250 family
ACZ76_RS14600	COG1686	Belongs to the peptidase S11 family
ACZ76_RS14605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACZ76_RS14610	COG0772	Belongs to the SEDS family
ACZ76_RS14615	COG0768	penicillin binding
ACZ76_RS14625	COG0799	negative regulation of ribosome biogenesis
ACZ76_RS14630	COG0582	viral genome integration into host DNA
ACZ76_RS14690	COG4712	double-strand break repair protein
ACZ76_RS14735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACZ76_RS14755	COG0305	Participates in initiation and elongation during chromosome replication
ACZ76_RS14845	COG1783	phage Terminase large subunit
ACZ76_RS14910	COG2755	lipolytic protein G-D-S-L family
ACZ76_RS14910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ACZ76_RS14915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACZ76_RS14920	COG1466	dna polymerase III delta subunit
ACZ76_RS14925	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ACZ76_RS14935	COG2888	peptidyl-tyrosine sulfation
ACZ76_RS14945	COG1126	abc transporter atp-binding protein
ACZ76_RS14950	COG0765	amino acid transport
ACZ76_RS14955	COG0765	amino acid transport
ACZ76_RS14970	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ACZ76_RS14975	COG4535	Mg2 and Co2 transporter CorC
ACZ76_RS14980	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACZ76_RS14985	COG1702	phosphate starvation-inducible protein PhoH
ACZ76_RS14990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACZ76_RS14995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACZ76_RS15030	COG0367	asparagine synthase
ACZ76_RS15035	COG0647	UMP catabolic process
ACZ76_RS15040	COG1846	Transcriptional regulator
ACZ76_RS15040	COG1940	carbohydrate kinase activity
ACZ76_RS15045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACZ76_RS15055	COG2190	(PTS) system
ACZ76_RS15055	COG1263	PTS System
ACZ76_RS15055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS15060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACZ76_RS15090	COG0735	belongs to the Fur family
ACZ76_RS15100	COG0840	transmembrane signaling receptor activity
ACZ76_RS15110	COG0596	Alpha beta hydrolase
ACZ76_RS15115	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ACZ76_RS15120	COG0033	Phosphoglucomutase
ACZ76_RS15135	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS15140	COG2205	protein histidine kinase activity
ACZ76_RS15145	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACZ76_RS15150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACZ76_RS15155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACZ76_RS15170	COG3272	Protein of unknown function (DUF1722)
ACZ76_RS15180	COG5212	phosphodiesterase
ACZ76_RS15185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACZ76_RS15190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACZ76_RS15195	COG1984	allophanate hydrolase subunit 2
ACZ76_RS15200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACZ76_RS15230	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACZ76_RS15235	COG1053	succinate dehydrogenase
ACZ76_RS15240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACZ76_RS15245	COG0567	Dehydrogenase, E1 component
ACZ76_RS15250	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACZ76_RS15255	COG0045	succinate-CoA ligase (ADP-forming) activity
ACZ76_RS15260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACZ76_RS15265	COG0737	Belongs to the 5'-nucleotidase family
ACZ76_RS15270	COG1271	oxidase subunit
ACZ76_RS15275	COG1294	oxidase, subunit
ACZ76_RS15280	COG4890	Cyd operon protein YbgT
ACZ76_RS15285	COG3790	cyd operon protein YbgE
ACZ76_RS15290	COG0824	Thioesterase
ACZ76_RS15295	COG0811	peptide transport
ACZ76_RS15300	COG0848	biopolymer transport protein
ACZ76_RS15305	COG3064	Membrane
ACZ76_RS15305	COG3064	Membrane
ACZ76_RS15310	COG0823	Involved in the tonB-independent uptake of proteins
ACZ76_RS15315	COG2885	chlorophyll binding
ACZ76_RS15320	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ACZ76_RS15355	COG1230	cation diffusion facilitator family transporter
ACZ76_RS15360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACZ76_RS15365	COG0588	phosphoglycerate mutase activity
ACZ76_RS15375	COG2017	converts alpha-aldose to the beta-anomer
ACZ76_RS15380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACZ76_RS15385	COG1085	galactose-1-phosphate uridylyltransferase
ACZ76_RS15390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACZ76_RS15400	COG1119	ATPase activity
ACZ76_RS15405	COG2005	Transcriptional regulator
ACZ76_RS15405	COG3585	molybdate ion transport
ACZ76_RS15415	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACZ76_RS15420	COG4149	molybdate abc transporter
ACZ76_RS15430	COG3037	sugar-specific permease SgaT UlaA
ACZ76_RS15440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACZ76_RS15445	COG1609	Transcriptional regulator
ACZ76_RS15450	COG0857	belongs to the CobB CobQ family
ACZ76_RS15450	COG0280	phosphate acetyltransferase
ACZ76_RS15460	COG3092	negative regulation of chromosome organization
ACZ76_RS15465	COG3013	Belongs to the UPF0304 family
ACZ76_RS15470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACZ76_RS15480	COG0490	domain, Protein
ACZ76_RS15480	COG0471	metal ion transport
ACZ76_RS15485	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ACZ76_RS15490	COG0436	Aminotransferase
ACZ76_RS15495	COG0583	DNA-binding transcription factor activity
ACZ76_RS15500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACZ76_RS15505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACZ76_RS15510	COG0649	NAD binding
ACZ76_RS15510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACZ76_RS15525	COG1034	ATP synthesis coupled electron transport
ACZ76_RS15530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACZ76_RS15535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACZ76_RS15540	COG0839	Belongs to the complex I subunit 6 family
ACZ76_RS15545	COG0713	ATP synthesis coupled electron transport
ACZ76_RS15550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACZ76_RS15555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACZ76_RS15560	COG1007	ATP synthesis coupled electron transport
ACZ76_RS15590	COG3265	gluconokinase activity
ACZ76_RS15595	COG1028	Short-chain dehydrogenase reductase Sdr
ACZ76_RS15600	COG1609	Transcriptional regulator
ACZ76_RS15605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACZ76_RS15615	COG4702	Belongs to the UPF0303 family
ACZ76_RS15620	COG0129	dihydroxy-acid dehydratase activity
ACZ76_RS15625	COG4575	ribosome binding
ACZ76_RS15635	COG1169	isochorismate synthase
ACZ76_RS15640	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ACZ76_RS15650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ACZ76_RS15655	COG1441	menaquinone biosynthetic process
ACZ76_RS15680	COG0814	amino acid
ACZ76_RS15715	COG4574	serine-type endopeptidase inhibitor activity
ACZ76_RS15720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACZ76_RS15730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACZ76_RS15735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ76_RS15745	COG0784	Response regulator, receiver
ACZ76_RS15745	COG2205	protein histidine kinase activity
ACZ76_RS15755	COG0642	Histidine kinase
ACZ76_RS15755	COG2198	Histidine kinase
ACZ76_RS15760	COG2223	nitrite transmembrane transporter activity
ACZ76_RS15790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACZ76_RS15845	COG4386	tail sheath protein
ACZ76_RS15885	COG3299	homolog of phage Mu protein gp47
ACZ76_RS15905	COG1737	Transcriptional regulator
ACZ76_RS15910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS15910	COG2190	(PTS) system
ACZ76_RS15910	COG1263	PTS System
ACZ76_RS15915	COG2723	6-phospho-beta-galactosidase activity
ACZ76_RS15930	COG3423	Transcriptional regulator
ACZ76_RS15960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACZ76_RS15980	COG3082	Protein of unknown function (DUF1414)
ACZ76_RS15985	COG3081	Nucleoid-associated protein
ACZ76_RS15995	COG1061	Type III restriction enzyme res subunit
ACZ76_RS16000	COG1187	pseudouridine synthase activity
ACZ76_RS16005	COG2814	Major facilitator Superfamily
ACZ76_RS16015	COG4172	Belongs to the ABC transporter superfamily
ACZ76_RS16020	COG4239	(ABC) transporter, permease
ACZ76_RS16025	COG4174	ABC transporter (Permease)
ACZ76_RS16030	COG4166	transmembrane transport
ACZ76_RS16035	COG2200	EAL domain
ACZ76_RS16040	COG0791	NLP P60 protein
ACZ76_RS16045	COG0671	phosphoesterase, PA-phosphatase related
ACZ76_RS16050	COG0523	cobalamin synthesis protein
ACZ76_RS16060	COG2186	Transcriptional regulator
ACZ76_RS16065	COG0246	Mannitol dehydrogenase
ACZ76_RS16075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACZ76_RS16090	COG0243	molybdopterin cofactor binding
ACZ76_RS16095	COG3005	denitrification pathway
ACZ76_RS16110	COG1105	Belongs to the carbohydrate kinase PfkB family
ACZ76_RS16115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACZ76_RS16115	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACZ76_RS16115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACZ76_RS16120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACZ76_RS16125	COG2855	membrane
ACZ76_RS16140	COG0583	DNA-binding transcription factor activity
ACZ76_RS16145	COG0833	amino acid
ACZ76_RS16150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACZ76_RS16160	COG4771	TonB-dependent receptor
ACZ76_RS16165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ76_RS16185	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ACZ76_RS16190	COG0625	glutathione transferase activity
ACZ76_RS16215	COG2011	ABC-type metal ion transport system permease component
ACZ76_RS16225	COG0626	cystathionine gamma-synthase activity
ACZ76_RS16235	COG1686	Belongs to the peptidase S11 family
ACZ76_RS16240	COG1760	l-serine dehydratase
ACZ76_RS16245	COG0814	amino acid
ACZ76_RS16250	COG1349	DNA-binding transcription factor activity
ACZ76_RS16260	COG0671	phosphoesterase, PA-phosphatase related
ACZ76_RS16270	COG2985	domain, Protein
ACZ76_RS16270	COG0569	domain protein
ACZ76_RS16290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ACZ76_RS16295	COG3842	ATPase activity
ACZ76_RS16300	COG1176	ABC-type spermidine putrescine transport system, permease component I
ACZ76_RS16305	COG1177	transmembrane transport
ACZ76_RS16320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS16325	COG4160	amino acid transport
ACZ76_RS16330	COG4215	(ABC) transporter
ACZ76_RS16335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACZ76_RS16340	COG1126	abc transporter atp-binding protein
ACZ76_RS16345	COG1605	Chorismate mutase
ACZ76_RS16355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACZ76_RS16360	COG0702	epimerase
ACZ76_RS16365	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ACZ76_RS16375	COG0028	Belongs to the TPP enzyme family
ACZ76_RS16380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACZ76_RS16385	COG1151	hydroxylamine reductase activity
ACZ76_RS16390	COG2431	L-lysine efflux transmembrane transporter activity
ACZ76_RS16395	COG3593	DNA synthesis involved in DNA repair
ACZ76_RS16400	COG2990	Protein conserved in bacteria
ACZ76_RS16405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACZ76_RS16415	COG1278	Cold shock
ACZ76_RS16420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACZ76_RS16425	COG0542	response to heat
ACZ76_RS16430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACZ76_RS16435	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACZ76_RS16440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACZ76_RS16450	COG0492	ferredoxin-NADP+ reductase activity
ACZ76_RS16460	COG1674	ftsk spoiiie
ACZ76_RS16460	COG3107	peptidoglycan biosynthetic process
ACZ76_RS16465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACZ76_RS16470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACZ76_RS16475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACZ76_RS16480	COG2814	Major facilitator Superfamily
ACZ76_RS16485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACZ76_RS16490	COG1882	Formate acetyltransferase
ACZ76_RS16495	COG2116	formate transmembrane transporter activity
ACZ76_RS16500	COG1944	ATP diphosphatase activity
ACZ76_RS16505	COG0252	asparaginase activity
ACZ76_RS16510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACZ76_RS16515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACZ76_RS16520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACZ76_RS16525	COG0539	negative regulation of cytoplasmic translation
ACZ76_RS16530	COG0776	regulation of translation
ACZ76_RS16535	COG2333	competence protein COMEC
ACZ76_RS16535	COG0658	competence protein
ACZ76_RS16550	COG5383	Protein conserved in bacteria
ACZ76_RS16555	COG1278	Cold shock
ACZ76_RS16560	COG2835	tetraacyldisaccharide 4'-kinase activity
ACZ76_RS16570	COG3173	Aminoglycoside phosphotransferase
ACZ76_RS16575	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ACZ76_RS16580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACZ76_RS16585	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ACZ76_RS16600	COG2989	Protein conserved in bacteria
ACZ76_RS16605	COG3108	Peptidase M15
ACZ76_RS16610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACZ76_RS16615	COG2200	EAL domain
ACZ76_RS16620	COG1448	Aminotransferase
ACZ76_RS16630	COG0017	Asparaginyl-tRNA synthetase
ACZ76_RS16635	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACZ76_RS16640	COG0308	aminopeptidase N
ACZ76_RS16645	COG0167	dihydroorotate dehydrogenase activity
ACZ76_RS16655	COG3217	Mosc domain protein beta barrel domain protein
ACZ76_RS16655	COG0633	Ferredoxin
ACZ76_RS16660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACZ76_RS16660	COG0116	Belongs to the methyltransferase superfamily
ACZ76_RS16665	COG0488	(ABC) transporter
ACZ76_RS16670	COG2995	paraquat-inducible protein a
ACZ76_RS16675	COG3008	intermembrane lipid transfer
ACZ76_RS16675	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACZ76_RS16680	COG3009	Protein conserved in bacteria
ACZ76_RS16685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACZ76_RS16695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ACZ76_RS16700	COG1067	ATP-dependent peptidase activity
ACZ76_RS16705	COG3120	sequence-specific DNA binding
ACZ76_RS16715	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
ACZ76_RS16720	COG3070	regulator of competence-specific genes
ACZ76_RS16725	COG1289	transmembrane transporter activity
ACZ76_RS16730	COG3304	Inner membrane component domain
ACZ76_RS16735	COG0210	DNA helicase
ACZ76_RS16740	COG1803	Methylglyoxal synthase
ACZ76_RS16750	COG1832	CoA-binding protein
ACZ76_RS16755	COG3785	DNA binding
ACZ76_RS16760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ACZ76_RS16780	COG1254	Belongs to the acylphosphatase family
ACZ76_RS16785	COG2920	part of a sulfur-relay system
ACZ76_RS16825	COG2375	cellular response to nickel ion
ACZ76_RS16835	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ACZ76_RS16840	COG0437	4 iron, 4 sulfur cluster binding
ACZ76_RS16845	COG3301	Polysulphide reductase, NrfD
ACZ76_RS16850	COG1138	Cytochrome C-type biogenesis protein
ACZ76_RS16855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACZ76_RS16860	COG3088	subunit of a heme lyase
ACZ76_RS16865	COG4235	cytochrome complex assembly
ACZ76_RS16865	COG3088	subunit of a heme lyase
ACZ76_RS16870	COG2771	luxR family
ACZ76_RS16875	COG3916	Acyl-homoserine-lactone synthase
ACZ76_RS16885	COG3263	regulation of cellular component size
ACZ76_RS16900	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ACZ76_RS16905	COG2943	transferase activity, transferring hexosyl groups
ACZ76_RS16910	COG5645	(Lipo)protein
ACZ76_RS16925	COG2814	Major facilitator Superfamily
ACZ76_RS16930	COG2259	Doxx family
ACZ76_RS16935	COG1560	Kdo2-lipid A biosynthetic process
ACZ76_RS16975	COG0628	permease
ACZ76_RS17000	COG0418	dihydroorotase activity
ACZ76_RS17005	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACZ76_RS17010	COG1530	ribonuclease E activity
ACZ76_RS17010	COG1530	ribonuclease E activity
ACZ76_RS17015	COG0564	pseudouridine synthase activity
ACZ76_RS17025	COG1399	metal-binding, possibly nucleic acid-binding protein
ACZ76_RS17030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACZ76_RS17035	COG0416	fatty acid biosynthetic process
ACZ76_RS17060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACZ76_RS17065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACZ76_RS17070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACZ76_RS17075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACZ76_RS17080	COG0470	DNA polymerase III
ACZ76_RS17085	COG0084	hydrolase, TatD family'
ACZ76_RS17090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACZ76_RS17090	COG1263	PTS System
ACZ76_RS17225	COG4695	Portal protein
ACZ76_RS17290	COG4974	Belongs to the 'phage' integrase family
ACZ76_RS17320	COG0641	radical SAM
ACZ76_RS17325	COG4533	DNA binding
ACZ76_RS17330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACZ76_RS17335	COG0537	adenosine 5'-monophosphoramidase activity
ACZ76_RS17340	COG5633	Lipoprotein
ACZ76_RS17345	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ACZ76_RS17360	COG3150	esterase
ACZ76_RS17365	COG1252	NADH dehydrogenase
ACZ76_RS17370	COG3134	Outer membrane lipoprotein
ACZ76_RS17375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACZ76_RS17380	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACZ76_RS17390	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACZ76_RS17395	COG1940	carbohydrate kinase activity
ACZ76_RS17410	COG2850	peptidyl-arginine hydroxylation
ACZ76_RS17420	COG0745	RESPONSE REGULATOR receiver
ACZ76_RS17430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACZ76_RS17435	COG2915	High frequency lysogenization protein hflD homolog
ACZ76_RS17440	COG0482	sulfurtransferase activity
ACZ76_RS17450	COG1187	pseudouridine synthase activity
ACZ76_RS17455	COG0538	isocitrate dehydrogenase activity
ACZ76_RS17465	COG0561	phosphatase activity
ACZ76_RS17470	COG2223	nitrite transmembrane transporter activity
ACZ76_RS17485	COG3711	transcriptional antiterminator
ACZ76_RS17490	COG3493	citrate carrier protein
ACZ76_RS17495	COG4565	transcriptional regulatory protein
ACZ76_RS17500	COG3290	protein histidine kinase activity
ACZ76_RS17505	COG2066	Belongs to the glutaminase family
ACZ76_RS17520	COG1609	Transcriptional regulator
ACZ76_RS17525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ACZ76_RS17530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ACZ76_RS17535	COG2723	6-phospho-beta-galactosidase activity
ACZ76_RS17540	COG1447	Phosphotransferase system cellobiose-specific component IIA
ACZ76_RS17550	COG0672	)-iron permease
ACZ76_RS17565	COG1136	(ABC) transporter
ACZ76_RS17565	COG0577	efflux transmembrane transporter activity
ACZ76_RS17575	COG0577	efflux transmembrane transporter activity
ACZ76_RS17575	COG1136	(ABC) transporter
ACZ76_RS17605	COG0006	proline dipeptidase activity
ACZ76_RS17610	COG0457	Tetratricopeptide repeat
ACZ76_RS17615	COG1649	PFAM Uncharacterised BCR, COG1649
ACZ76_RS17615	COG0726	polysaccharide deacetylase
ACZ76_RS17620	COG1215	transferase activity, transferring glycosyl groups
ACZ76_RS17625	COG3658	cytochrome
ACZ76_RS17635	COG1702	phosphate starvation-inducible protein PhoH
ACZ76_RS17640	COG0387	Pfam Sodium calcium exchanger
ACZ76_RS17650	COG0583	DNA-binding transcription factor activity
ACZ76_RS17655	COG3850	Histidine kinase
ACZ76_RS17660	COG1294	oxidase, subunit
ACZ76_RS17665	COG1271	oxidase subunit
ACZ76_RS17670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACZ76_RS17675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACZ76_RS17680	COG3138	arginine N-succinyltransferase
ACZ76_RS17690	COG3724	N-succinylarginine dihydrolase activity
ACZ76_RS17695	COG2988	succinylglutamate desuccinylase activity
ACZ76_RS17710	COG1228	amidohydrolase
ACZ76_RS17735	COG1129	ABC transporter
ACZ76_RS17740	COG4211	Belongs to the binding-protein-dependent transport system permease family
ACZ76_RS17745	COG3443	Belongs to the bacterial solute-binding protein 9 family
ACZ76_RS17755	COG4942	peptidase
ACZ76_RS17765	COG0738	Major facilitator superfamily
ACZ76_RS17770	COG0583	DNA-binding transcription factor activity
ACZ76_RS17775	COG2271	Major facilitator Superfamily
ACZ76_RS17790	COG4670	ketone body catabolic process
ACZ76_RS17795	COG1960	acyl-CoA dehydrogenase activity
ACZ76_RS17800	COG1917	Cupin 2, conserved barrel domain protein
ACZ76_RS17800	COG2207	Transcriptional regulator
ACZ76_RS17805	COG2086	electron transfer activity
ACZ76_RS17810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACZ76_RS17815	COG0644	oxidoreductase
ACZ76_RS17820	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACZ76_RS17825	COG0318	PFAM AMP-dependent synthetase and ligase
ACZ76_RS17835	COG1472	Belongs to the glycosyl hydrolase 3 family
ACZ76_RS17860	COG2197	response regulator
ACZ76_RS17865	COG0012	GTP binding
ACZ76_RS17875	COG0193	aminoacyl-tRNA hydrolase activity
ACZ76_RS17940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACZ76_RS17950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACZ76_RS17965	COG1401	restriction endodeoxyribonuclease activity
ACZ76_RS17980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACZ76_RS17990	COG3210	domain, Protein