locus-tag	class	description
FORC2_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC2_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC2_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC2_RS00020	COG0187	DNA topoisomerase II activity
FORC2_RS00025	COG0561	phosphatase activity
FORC2_RS00030	COG1940	carbohydrate kinase activity
FORC2_RS00035	COG2423	ornithine cyclodeaminase activity
FORC2_RS00040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC2_RS00045	COG0823	Involved in the tonB-independent uptake of proteins
FORC2_RS00050	COG5645	(Lipo)protein
FORC2_RS00065	COG2985	domain, Protein
FORC2_RS00065	COG0569	domain protein
FORC2_RS00070	COG3977	Valine--pyruvate aminotransferase
FORC2_RS00075	COG0366	Alpha amylase catalytic
FORC2_RS00080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC2_RS00095	COG2885	chlorophyll binding
FORC2_RS00115	COG2818	Glycosylase
FORC2_RS00120	COG0752	glycyl-tRNA synthetase alpha subunit
FORC2_RS00125	COG0751	glycine-tRNA ligase activity
FORC2_RS00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS00135	COG2213	PTS system mannitol-specific
FORC2_RS00140	COG0246	Mannitol dehydrogenase
FORC2_RS00145	COG3722	fumarate hydratase activity
FORC2_RS00155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC2_RS00175	COG2258	MOSC domain
FORC2_RS00180	COG0840	transmembrane signaling receptor activity
FORC2_RS00185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC2_RS00190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC2_RS00195	COG0243	molybdopterin cofactor binding
FORC2_RS00195	COG3383	formate dehydrogenase (NAD+) activity
FORC2_RS00200	COG3383	formate dehydrogenase (NAD+) activity
FORC2_RS00200	COG0243	molybdopterin cofactor binding
FORC2_RS00205	COG0437	4 iron, 4 sulfur cluster binding
FORC2_RS00210	COG2864	formate dehydrogenase
FORC2_RS00215	COG3058	Necessary for formate dehydrogenase activity
FORC2_RS00220	COG1921	L-seryl-tRNASec selenium transferase activity
FORC2_RS00225	COG3276	selenocysteine insertion sequence binding
FORC2_RS00235	COG3274	enterobacterial common antigen metabolic process
FORC2_RS00250	COG3121	Chaperone
FORC2_RS00255	COG1070	Carbohydrate kinase
FORC2_RS00260	COG2115	Belongs to the xylose isomerase family
FORC2_RS00265	COG4213	ABC transporter substrate-binding protein
FORC2_RS00275	COG4214	carbohydrate transport
FORC2_RS00280	COG2207	Transcriptional regulator
FORC2_RS00280	COG1609	Transcriptional regulator
FORC2_RS00285	COG0582	viral genome integration into host DNA
FORC2_RS00340	COG1609	Transcriptional regulator
FORC2_RS00345	COG1940	carbohydrate kinase activity
FORC2_RS00350	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC2_RS00355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC2_RS00360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC2_RS00365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC2_RS00380	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS00385	COG1482	cell wall glycoprotein biosynthetic process
FORC2_RS00405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC2_RS00410	COG2986	histidine ammonia-lyase
FORC2_RS00425	COG1764	response to oxidative stress
FORC2_RS00430	COG2194	sulfuric ester hydrolase activity
FORC2_RS00435	COG2197	response regulator
FORC2_RS00440	COG3851	Histidine kinase
FORC2_RS00445	COG2271	Major facilitator Superfamily
FORC2_RS00455	COG3210	domain, Protein
FORC2_RS00460	COG2831	hemolysin activation secretion protein
FORC2_RS00465	COG3210	domain, Protein
FORC2_RS00470	COG0747	negative chemotaxis
FORC2_RS00475	COG0601	transmembrane transport
FORC2_RS00480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC2_RS00485	COG0444	Belongs to the ABC transporter superfamily
FORC2_RS00490	COG4608	Belongs to the ABC transporter superfamily
FORC2_RS00495	COG2194	sulfuric ester hydrolase activity
FORC2_RS00515	COG1192	Involved in chromosome partitioning
FORC2_RS00530	COG1215	transferase activity, transferring glycosyl groups
FORC2_RS00535	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC2_RS00540	COG3118	belongs to the thioredoxin family
FORC2_RS00540	COG0457	Tetratricopeptide repeat
FORC2_RS00545	COG2200	EAL domain
FORC2_RS00545	COG2199	diguanylate cyclase activity
FORC2_RS00550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC2_RS00565	COG1301	dicarboxylic acid transport
FORC2_RS00570	COG0612	Peptidase, M16
FORC2_RS00575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC2_RS00580	COG1942	4-Oxalocrotonate Tautomerase
FORC2_RS00585	COG2200	EAL domain
FORC2_RS00590	COG2982	Protein involved in outer membrane biogenesis
FORC2_RS00595	COG2134	cdp-diacylglycerol pyrophosphatase
FORC2_RS00600	COG1295	ribonuclease BN
FORC2_RS00615	COG1396	sequence-specific DNA binding
FORC2_RS00665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC2_RS00715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC2_RS00720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC2_RS00730	COG0742	ribosomal rna small subunit methyltransferase
FORC2_RS00745	COG0589	response to stress
FORC2_RS00755	COG0306	phosphate transporter
FORC2_RS00760	COG2081	HI0933 family
FORC2_RS00765	COG1301	dicarboxylic acid transport
FORC2_RS00780	COG3799	methylaspartate ammonia-lyase activity
FORC2_RS00785	COG4865	methylaspartate mutase activity
FORC2_RS00795	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC2_RS00805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC2_RS00805	COG1648	precorrin-2 dehydrogenase activity
FORC2_RS00810	COG0583	DNA-binding transcription factor activity
FORC2_RS00815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC2_RS00815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC2_RS00825	COG0561	phosphatase activity
FORC2_RS00835	COG0583	DNA-binding transcription factor activity
FORC2_RS00840	COG2814	Major facilitator Superfamily
FORC2_RS00855	COG3718	enzyme involved in inositol metabolism
FORC2_RS00865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC2_RS00875	COG0673	inositol 2-dehydrogenase activity
FORC2_RS00880	COG1082	Xylose isomerase domain protein TIM barrel
FORC2_RS00885	COG1247	-acetyltransferase
FORC2_RS00890	COG1741	Belongs to the pirin family
FORC2_RS00895	COG1609	Transcriptional regulator
FORC2_RS00900	COG2610	gluconate transmembrane transporter activity
FORC2_RS00905	COG3265	gluconokinase activity
FORC2_RS00910	COG2095	MarC family integral membrane protein
FORC2_RS00915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC2_RS00935	COG3275	phosphorelay sensor kinase activity
FORC2_RS00940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC2_RS00945	COG1523	belongs to the glycosyl hydrolase 13 family
FORC2_RS00955	COG0297	glycogen (starch) synthase activity
FORC2_RS00960	COG0058	SHG alpha-glucan phosphorylase activity
FORC2_RS00965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC2_RS00970	COG1349	DNA-binding transcription factor activity
FORC2_RS00975	COG0705	Rhomboid family
FORC2_RS00990	COG2909	trisaccharide binding
FORC2_RS00995	COG0058	SHG alpha-glucan phosphorylase activity
FORC2_RS01000	COG1640	4-alpha-glucanotransferase
FORC2_RS01005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC2_RS01005	COG0316	Belongs to the HesB IscA family
FORC2_RS01015	COG0596	Alpha beta hydrolase
FORC2_RS01030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC2_RS01035	COG1918	ferrous iron import across plasma membrane
FORC2_RS01040	COG2183	response to ionizing radiation
FORC2_RS01045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC2_RS01060	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC2_RS01070	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC2_RS01075	COG1011	Hydrolase
FORC2_RS01085	COG0494	nUDIX hydrolase
FORC2_RS01090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC2_RS01115	COG4796	Type ii and iii secretion system protein
FORC2_RS01120	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC2_RS01140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC2_RS01150	COG0180	Tryptophanyl-tRNA synthetase
FORC2_RS01155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC2_RS01155	COG1648	precorrin-2 dehydrogenase activity
FORC2_RS01170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC2_RS01175	COG0402	S-adenosylhomocysteine deaminase activity
FORC2_RS01180	COG0738	Major facilitator superfamily
FORC2_RS01190	COG1486	melibiose metabolic process
FORC2_RS01195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC2_RS01200	COG0433	COG0433 Predicted ATPase
FORC2_RS01215	COG1289	transmembrane transporter activity
FORC2_RS01225	COG1765	OsmC-like protein
FORC2_RS01230	COG3954	Phosphoribulokinase
FORC2_RS01235	COG3089	Belongs to the UPF0270 family
FORC2_RS01240	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC2_RS01255	COG4521	taurine ABC transporter
FORC2_RS01265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC2_RS01270	COG2175	clavaminate synthase activity
FORC2_RS01280	COG1216	Glycosyl transferase, family 2
FORC2_RS01285	COG0488	(ABC) transporter
FORC2_RS01290	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC2_RS01300	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FORC2_RS01305	COG1047	Peptidyl-prolyl cis-trans
FORC2_RS01310	COG2900	Belongs to the SlyX family
FORC2_RS01315	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC2_RS01320	COG2964	Protein conserved in bacteria
FORC2_RS01325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC2_RS01330	COG2923	Belongs to the DsrF TusC family
FORC2_RS01335	COG2168	tRNA wobble position uridine thiolation
FORC2_RS01340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC2_RS01345	COG0049	tRNA binding
FORC2_RS01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC2_RS01370	COG0051	transcription antitermination factor activity, RNA binding
FORC2_RS01375	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC2_RS01380	COG0088	Forms part of the polypeptide exit tunnel
FORC2_RS01385	COG0089	rRNA binding
FORC2_RS01390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC2_RS01395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC2_RS01400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC2_RS01405	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC2_RS01410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FORC2_RS01415	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC2_RS01420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC2_RS01425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC2_RS01430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC2_RS01435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC2_RS01440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC2_RS01450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC2_RS01455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FORC2_RS01465	COG1841	ribosomal large subunit assembly
FORC2_RS01470	COG0200	Binds to the 23S rRNA
FORC2_RS01475	COG0201	protein transport
FORC2_RS01480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC2_RS01485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC2_RS01490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC2_RS01495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FORC2_RS01500	COG0202	RNA polymerase activity
FORC2_RS01505	COG0203	ribosomal protein L17
FORC2_RS01515	COG0789	Transcriptional regulator
FORC2_RS01520	COG3036	rescue of stalled ribosome
FORC2_RS01525	COG1970	mechanosensitive ion channel activity
FORC2_RS01535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC2_RS01535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC2_RS01540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC2_RS01545	COG0242	peptide deformylase activity
FORC2_RS01550	COG0758	DNA mediated transformation
FORC2_RS01560	COG0551	DNA topoisomerase type I activity
FORC2_RS01565	COG0009	L-threonylcarbamoyladenylate synthase
FORC2_RS01570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC2_RS01575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC2_RS01600	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC2_RS01605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC2_RS01615	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FORC2_RS01620	COG1414	Transcriptional regulator
FORC2_RS01645	COG0527	aspartate kinase activity
FORC2_RS01650	COG0166	Belongs to the GPI family
FORC2_RS01655	COG3223	Belongs to the PsiE family
FORC2_RS01660	COG3833	ABC-type maltose transport systems, permease component
FORC2_RS01665	COG1175	transmembrane transport
FORC2_RS01670	COG2182	Extracellular solute-binding protein
FORC2_RS01680	COG4580	involved in the transport of maltose and maltodextrins
FORC2_RS01690	COG3161	chorismate lyase activity
FORC2_RS01695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC2_RS01700	COG2937	Belongs to the GPAT DAPAT family
FORC2_RS01705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC2_RS01710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC2_RS01715	COG3237	CsbD-like
FORC2_RS01720	COG0735	belongs to the Fur family
FORC2_RS01725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC2_RS01755	COG1448	Aminotransferase
FORC2_RS01760	COG2315	Protein conserved in bacteria
FORC2_RS01765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC2_RS01780	COG2252	PERMEase
FORC2_RS01785	COG0025	NhaP-type Na H and K H
FORC2_RS01790	COG0583	DNA-binding transcription factor activity
FORC2_RS01795	COG1380	Effector of murein hydrolase LrgA
FORC2_RS01805	COG1126	abc transporter atp-binding protein
FORC2_RS01810	COG0765	amino acid transport
FORC2_RS01815	COG4597	amino acid ABC transporter
FORC2_RS01820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS01830	COG1560	Kdo2-lipid A biosynthetic process
FORC2_RS01835	COG0471	metal ion transport
FORC2_RS01840	COG1278	Cold shock
FORC2_RS01845	COG1278	Cold shock
FORC2_RS01850	COG1278	Cold shock
FORC2_RS01855	COG3133	Outer membrane lipoprotein
FORC2_RS01865	COG0582	viral genome integration into host DNA
FORC2_RS01960	COG1802	Transcriptional regulator
FORC2_RS01960	COG4626	Terminase
FORC2_RS01975	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC2_RS01980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC2_RS01985	COG2264	protein methyltransferase activity
FORC2_RS01990	COG4145	pantothenate transmembrane transporter activity
FORC2_RS01995	COG3924	membrane
FORC2_RS02000	COG0439	Biotin carboxylase
FORC2_RS02005	COG0511	ligase activity, forming carbon-carbon bonds
FORC2_RS02010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC2_RS02015	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FORC2_RS02025	COG0604	alcohol dehydrogenase
FORC2_RS02030	COG2200	EAL domain
FORC2_RS02030	COG2199	diguanylate cyclase activity
FORC2_RS02035	COG1077	Cell shape determining protein MreB Mrl
FORC2_RS02040	COG1792	Involved in formation and maintenance of cell shape
FORC2_RS02045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC2_RS02050	COG0424	maF-like protein
FORC2_RS02055	COG1530	ribonuclease E activity
FORC2_RS02060	COG3164	Protein of unknown function
FORC2_RS02065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC2_RS02070	COG0312	modulator of DNA gyrase
FORC2_RS02110	COG0583	DNA-binding transcription factor activity
FORC2_RS02120	COG1566	PFAM secretion protein HlyD family protein
FORC2_RS02125	COG1289	transmembrane transporter activity
FORC2_RS02140	COG2732	(Barnase) inhibitor
FORC2_RS02145	COG3028	Belongs to the UPF0307 family
FORC2_RS02150	COG0312	modulator of DNA gyrase
FORC2_RS02155	COG3783	Cytochrome b(562)
FORC2_RS02160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC2_RS02190	COG3964	amidohydrolase
FORC2_RS02205	COG2706	6-phosphogluconolactonase activity
FORC2_RS02210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS02210	COG3711	transcriptional antiterminator
FORC2_RS02215	COG3093	addiction module antidote protein HigA
FORC2_RS02225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC2_RS02235	COG1263	PTS System
FORC2_RS02235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS02240	COG0366	Alpha amylase catalytic
FORC2_RS02260	COG2308	Evidence 4 Homologs of previously reported genes of
FORC2_RS02270	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC2_RS02275	COG0540	Belongs to the ATCase OTCase family
FORC2_RS02285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS02290	COG1660	Displays ATPase and GTPase activities
FORC2_RS02305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC2_RS02310	COG1137	ATPase activity
FORC2_RS02315	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC2_RS02320	COG3117	lipopolysaccharide transmembrane transporter activity
FORC2_RS02325	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FORC2_RS02330	COG0517	IMP dehydrogenase activity
FORC2_RS02330	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC2_RS02335	COG0530	calcium, potassium:sodium antiporter activity
FORC2_RS02340	COG1127	ABC transporter
FORC2_RS02345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC2_RS02350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC2_RS02355	COG2854	intermembrane phospholipid transfer
FORC2_RS02360	COG3113	response to antibiotic
FORC2_RS02365	COG5007	Belongs to the BolA IbaG family
FORC2_RS02370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC2_RS02375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC2_RS02380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC2_RS02385	COG3105	Protein conserved in bacteria
FORC2_RS02390	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC2_RS02395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC2_RS02400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC2_RS02405	COG0625	glutathione transferase activity
FORC2_RS02410	COG2969	positive regulation of protein catabolic process
FORC2_RS02420	COG0493	'glutamate synthase
FORC2_RS02425	COG0069	glutamate synthase activity
FORC2_RS02425	COG0070	glutamate synthase
FORC2_RS02425	COG0067	glutamate synthase
FORC2_RS02430	COG1242	4 iron, 4 sulfur cluster binding
FORC2_RS02435	COG5002	protein histidine kinase activity
FORC2_RS02435	COG2198	Histidine kinase
FORC2_RS02435	COG0784	Response regulator, receiver
FORC2_RS02440	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC2_RS02445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC2_RS02450	COG2823	Periplasmic or secreted lipoprotein
FORC2_RS02455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC2_RS02460	COG0792	nuclease activity
FORC2_RS02470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC2_RS02530	COG0667	Aldo Keto reductase
FORC2_RS02535	COG1064	alcohol dehydrogenase
FORC2_RS02540	COG1741	Belongs to the pirin family
FORC2_RS02545	COG0583	DNA-binding transcription factor activity
FORC2_RS02550	COG0435	Glutathione S-transferase
FORC2_RS02555	COG2259	Doxx family
FORC2_RS02565	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FORC2_RS02570	COG4575	ribosome binding
FORC2_RS02585	COG0586	Pfam SNARE associated Golgi protein
FORC2_RS02600	COG2271	Major facilitator Superfamily
FORC2_RS02605	COG1904	glucuronate isomerase
FORC2_RS02610	COG0246	Mannitol dehydrogenase
FORC2_RS02615	COG2721	sulfolactate sulfo-lyase activity
FORC2_RS02625	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC2_RS02630	COG0861	Integral membrane protein TerC family
FORC2_RS02635	COG0673	inositol 2-dehydrogenase activity
FORC2_RS02640	COG1451	nucleotide metabolic process
FORC2_RS02650	COG2813	Specifically methylates the guanine in position
FORC2_RS02655	COG1902	pentaerythritol trinitrate reductase activity
FORC2_RS02655	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC2_RS02665	COG3247	response to pH
FORC2_RS02670	COG2814	Major facilitator Superfamily
FORC2_RS02680	COG0076	glutamate decarboxylase activity
FORC2_RS02685	COG0531	amino acid
FORC2_RS02695	COG1263	PTS System
FORC2_RS02695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS02700	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC2_RS02710	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC2_RS02720	COG3876	Protein conserved in bacteria
FORC2_RS02745	COG4983	Phage plasmid primase, P4 family domain protein
FORC2_RS02790	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC2_RS02795	COG0542	response to heat
FORC2_RS02805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC2_RS02850	COG0501	Belongs to the peptidase M48B family
FORC2_RS02855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC2_RS02860	COG3039	Transposase
FORC2_RS02870	COG3596	GTP binding
FORC2_RS02880	COG2378	regulation of single-species biofilm formation
FORC2_RS02905	COG2003	Belongs to the UPF0758 family
FORC2_RS02935	COG0358	DNA primase activity
FORC2_RS02940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC2_RS02945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC2_RS02950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC2_RS02955	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC2_RS02960	COG1968	undecaprenyl-diphosphatase activity
FORC2_RS02965	COG0617	tRNA 3'-terminal CCA addition
FORC2_RS02970	COG4991	sh3 domain protein
FORC2_RS02975	COG3025	triphosphatase activity
FORC2_RS02980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC2_RS02985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC2_RS02985	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC2_RS02990	COG0531	amino acid
FORC2_RS03000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC2_RS03005	COG3384	dioxygenase
FORC2_RS03010	COG0754	glutathionylspermidine amidase activity
FORC2_RS03015	COG5463	Belongs to the UPF0441 family
FORC2_RS03020	COG1538	Outer membrane efflux protein
FORC2_RS03025	COG0494	nUDIX hydrolase
FORC2_RS03030	COG3151	Protein conserved in bacteria
FORC2_RS03035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FORC2_RS03040	COG3150	esterase
FORC2_RS03055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC2_RS03060	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC2_RS03065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC2_RS03075	COG2132	Multicopper oxidase
FORC2_RS03090	COG0656	L-ascorbic acid biosynthetic process
FORC2_RS03095	COG1979	alcohol dehydrogenase
FORC2_RS03100	COG2207	Transcriptional regulator
FORC2_RS03105	COG0586	Pfam SNARE associated Golgi protein
FORC2_RS03120	COG0848	biopolymer transport protein
FORC2_RS03170	COG4964	Belongs to the GSP D family
FORC2_RS03200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC2_RS03205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS03225	COG4774	siderophore transport
FORC2_RS03235	COG1120	ATPase activity
FORC2_RS03240	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC2_RS03245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC2_RS03250	COG4592	Periplasmic binding protein
FORC2_RS03255	COG2271	Major facilitator Superfamily
FORC2_RS03260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC2_RS03265	COG0840	transmembrane signaling receptor activity
FORC2_RS03285	COG3133	Outer membrane lipoprotein
FORC2_RS03290	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FORC2_RS03295	COG0437	4 iron, 4 sulfur cluster binding
FORC2_RS03300	COG5557	Pfam Polysulphide reductase, NrfD
FORC2_RS03305	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FORC2_RS03310	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FORC2_RS03315	COG1773	rubredoxin
FORC2_RS03325	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FORC2_RS03330	COG0298	carbon dioxide binding
FORC2_RS03335	COG0409	Hydrogenase expression formation protein
FORC2_RS03340	COG0309	Hydrogenase expression formation protein (HypE)
FORC2_RS03345	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FORC2_RS03350	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FORC2_RS03365	COG5001	Diguanylate cyclase
FORC2_RS03380	COG2197	response regulator
FORC2_RS03390	COG0477	Major facilitator Superfamily
FORC2_RS03405	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC2_RS03415	COG1609	Transcriptional regulator
FORC2_RS03420	COG0477	Major facilitator Superfamily
FORC2_RS03430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC2_RS03435	COG0697	spore germination
FORC2_RS03450	COG4607	ABC-type enterochelin transport system periplasmic component
FORC2_RS03460	COG4605	iron ion homeostasis
FORC2_RS03465	COG4604	ABC transporter, ATP-binding protein
FORC2_RS03470	COG0024	Methionine aminopeptidase
FORC2_RS03495	COG1289	transmembrane transporter activity
FORC2_RS03505	COG1982	Orn Lys Arg decarboxylase major
FORC2_RS03510	COG0531	amino acid
FORC2_RS03530	COG2197	response regulator
FORC2_RS03535	COG2205	protein histidine kinase activity
FORC2_RS03545	COG0745	RESPONSE REGULATOR receiver
FORC2_RS03560	COG1982	Orn Lys Arg decarboxylase major
FORC2_RS03570	COG0741	lytic transglycosylase activity
FORC2_RS03575	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC2_RS03580	COG1194	a g-specific adenine glycosylase
FORC2_RS03585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC2_RS03590	COG3171	Protein conserved in bacteria
FORC2_RS03605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC2_RS03610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC2_RS03615	COG1872	DUF167
FORC2_RS03620	COG0762	integral membrane protein
FORC2_RS03625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC2_RS03630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC2_RS03635	COG2805	Type II/IV secretion system protein
FORC2_RS03645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC2_RS03650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC2_RS03655	COG1678	Uncharacterized ACR, COG1678
FORC2_RS03660	COG0189	ligase activity
FORC2_RS03665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC2_RS03670	COG2356	endonuclease I
FORC2_RS03675	COG3091	SprT-like family
FORC2_RS03695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC2_RS03700	COG1166	arginine decarboxylase activity
FORC2_RS03710	COG0501	Belongs to the peptidase M48B family
FORC2_RS03715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC2_RS03720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC2_RS03725	COG0126	phosphoglycerate kinase activity
FORC2_RS03730	COG0191	fructose-bisphosphate aldolase activity
FORC2_RS03740	COG1279	arginine transmembrane transporter activity
FORC2_RS03750	COG0583	DNA-binding transcription factor activity
FORC2_RS03755	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC2_RS03760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC2_RS03765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC2_RS03770	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC2_RS03775	COG3079	Belongs to the UPF0149 family
FORC2_RS03780	COG0006	proline dipeptidase activity
FORC2_RS03785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC2_RS03790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC2_RS03795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FORC2_RS03800	COG0509	glycine decarboxylation via glycine cleavage system
FORC2_RS03810	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC2_RS03810	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC2_RS03820	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS03830	COG1272	protein, Hemolysin III
FORC2_RS03835	COG0354	folic acid binding
FORC2_RS03850	COG0745	RESPONSE REGULATOR receiver
FORC2_RS03855	COG2205	protein histidine kinase activity
FORC2_RS03860	COG4452	Inner membrane protein CreD
FORC2_RS03865	COG0716	FMN binding
FORC2_RS03870	COG4974	Belongs to the 'phage' integrase family
FORC2_RS03875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC2_RS03880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC2_RS03885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC2_RS03890	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC2_RS03900	COG0582	viral genome integration into host DNA
FORC2_RS04035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC2_RS04040	COG1393	Belongs to the ArsC family
FORC2_RS04045	COG4319	ketosteroid isomerase
FORC2_RS04050	COG3706	GGDEF domain
FORC2_RS04055	COG1522	sequence-specific DNA binding
FORC2_RS04070	COG2271	Major facilitator Superfamily
FORC2_RS04080	COG0484	heat shock protein binding
FORC2_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS04095	COG1733	regulation of RNA biosynthetic process
FORC2_RS04100	COG0288	reversible hydration of carbon dioxide
FORC2_RS04120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC2_RS04130	COG2165	general secretion pathway protein
FORC2_RS04160	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC2_RS04180	COG0840	transmembrane signaling receptor activity
FORC2_RS04200	COG2814	Major facilitator Superfamily
FORC2_RS04205	COG0583	DNA-binding transcription factor activity
FORC2_RS04215	COG1609	Transcriptional regulator
FORC2_RS04225	COG0204	Acyl-transferase
FORC2_RS04225	COG0318	PFAM AMP-dependent synthetase and ligase
FORC2_RS04230	COG0477	Major facilitator Superfamily
FORC2_RS04235	COG0667	Aldo Keto reductase
FORC2_RS04240	COG0861	Integral membrane protein TerC family
FORC2_RS04245	COG3066	DNA modification
FORC2_RS04255	COG1051	belongs to the nudix hydrolase family
FORC2_RS04265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORC2_RS04270	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC2_RS04275	COG2165	general secretion pathway protein
FORC2_RS04295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC2_RS04300	COG1025	Belongs to the peptidase M16 family
FORC2_RS04305	COG1074	ATP-dependent DNA helicase activity
FORC2_RS04310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC2_RS04315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC2_RS04315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC2_RS04320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC2_RS04340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC2_RS04345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC2_RS04350	COG2166	iron-sulfur cluster assembly
FORC2_RS04355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC2_RS04365	COG0583	DNA-binding transcription factor activity
FORC2_RS04370	COG2363	Small membrane protein
FORC2_RS04375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FORC2_RS04380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC2_RS04385	COG1611	Belongs to the LOG family
FORC2_RS04390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC2_RS04390	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC2_RS04400	COG3098	single-species biofilm formation
FORC2_RS04405	COG0564	pseudouridine synthase activity
FORC2_RS04420	COG2171	N-acyltransferase activity
FORC2_RS04425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC2_RS04440	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC2_RS04445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC2_RS04450	COG0528	UMP kinase activity
FORC2_RS04455	COG0233	cytoplasmic translational termination
FORC2_RS04460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC2_RS04470	COG0575	Belongs to the CDS family
FORC2_RS04475	COG0750	zinc metalloprotease
FORC2_RS04485	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC2_RS04490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC2_RS04495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC2_RS04500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC2_RS04510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC2_RS04515	COG0587	DNA-directed DNA polymerase activity
FORC2_RS04520	COG0825	malonyl-CoA metabolic process
FORC2_RS04525	COG1982	Orn Lys Arg decarboxylase major
FORC2_RS04530	COG0346	lactoylglutathione lyase activity
FORC2_RS04545	COG4568	rho-dependent transcription termination
FORC2_RS04555	COG4681	YaeQ
FORC2_RS04565	COG3015	lipoprotein NlpE involved in copper resistance
FORC2_RS04570	COG0442	prolyl-tRNA aminoacylation
FORC2_RS04575	COG1720	tRNA m6t6A37 methyltransferase activity
FORC2_RS04585	COG1464	Belongs to the NlpA lipoprotein family
FORC2_RS04590	COG2011	ABC-type metal ion transport system permease component
FORC2_RS04600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC2_RS04655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC2_RS04670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC2_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS04720	COG0656	L-ascorbic acid biosynthetic process
FORC2_RS04725	COG0583	DNA-binding transcription factor activity
FORC2_RS04730	COG2814	Major facilitator Superfamily
FORC2_RS04735	COG3021	interspecies interaction between organisms
FORC2_RS04740	COG1388	LysM domain
FORC2_RS04740	COG0741	lytic transglycosylase activity
FORC2_RS04745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC2_RS04750	COG2226	methyltransferase
FORC2_RS04755	COG0328	RNA-DNA hybrid ribonuclease activity
FORC2_RS04770	COG2113	Glycine betaine
FORC2_RS04775	COG4176	ABC-type proline glycine betaine transport system permease component
FORC2_RS04780	COG4175	Glycine betaine
FORC2_RS04785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC2_RS04795	COG1780	Probably involved in ribonucleotide reductase function
FORC2_RS04800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC2_RS04805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC2_RS04815	COG4575	ribosome binding
FORC2_RS04830	COG2207	Transcriptional regulator
FORC2_RS04855	COG1278	Cold shock
FORC2_RS04890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC2_RS04895	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC2_RS04905	COG0831	urea catabolic process
FORC2_RS04915	COG0804	urea catabolic process
FORC2_RS04920	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FORC2_RS04925	COG0830	nickel cation binding
FORC2_RS04930	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FORC2_RS04935	COG0829	nickel cation binding
FORC2_RS04940	COG4413	Urea transporter
FORC2_RS04945	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FORC2_RS04955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC2_RS04970	COG2133	pyrroloquinoline quinone binding
FORC2_RS04975	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC2_RS04980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC2_RS04985	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS04990	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC2_RS04995	COG1917	Cupin 2, conserved barrel domain protein
FORC2_RS04995	COG2169	Transcriptional regulator
FORC2_RS05000	COG3394	polysaccharide catabolic process
FORC2_RS05005	COG0659	secondary active sulfate transmembrane transporter activity
FORC2_RS05050	COG2826	transposase and inactivated derivatives, IS30 family
FORC2_RS05070	COG3547	Transposase (IS116 IS110 IS902 family)
FORC2_RS05075	COG1063	alcohol dehydrogenase
FORC2_RS05095	COG1902	pentaerythritol trinitrate reductase activity
FORC2_RS05110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FORC2_RS05120	COG2826	transposase and inactivated derivatives, IS30 family
FORC2_RS05185	COG0582	viral genome integration into host DNA
FORC2_RS05190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC2_RS05195	COG2867	negative regulation of translational initiation
FORC2_RS05205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC2_RS05210	COG0497	DNA recombination
FORC2_RS05215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC2_RS05220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC2_RS05225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC2_RS05230	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC2_RS05245	COG0513	Belongs to the DEAD box helicase family
FORC2_RS05250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC2_RS05255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC2_RS05265	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FORC2_RS05275	COG3086	response to oxidative stress
FORC2_RS05285	COG0481	GTPase activity
FORC2_RS05295	COG0571	ribonuclease III activity
FORC2_RS05300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC2_RS05305	COG1381	Involved in DNA repair and RecF pathway recombination
FORC2_RS05310	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC2_RS05315	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC2_RS05325	COG2610	gluconate transmembrane transporter activity
FORC2_RS05330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC2_RS05335	COG1737	Transcriptional regulator
FORC2_RS05345	COG0560	Phosphoserine phosphatase
FORC2_RS05360	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC2_RS05375	COG2205	protein histidine kinase activity
FORC2_RS05380	COG3170	Tfp pilus assembly protein FimV
FORC2_RS05385	COG2204	response regulator
FORC2_RS05390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC2_RS05390	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC2_RS05395	COG0347	Belongs to the P(II) protein family
FORC2_RS05410	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FORC2_RS05415	COG3457	Alanine racemase
FORC2_RS05425	COG2188	Transcriptional regulator
FORC2_RS05430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC2_RS05430	COG1017	nitric oxide dioxygenase activity
FORC2_RS05435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC2_RS05440	COG2814	Major facilitator Superfamily
FORC2_RS05445	COG3711	transcriptional antiterminator
FORC2_RS05450	COG3683	transport system, periplasmic component
FORC2_RS05455	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FORC2_RS05465	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FORC2_RS05470	COG1959	2 iron, 2 sulfur cluster binding
FORC2_RS05480	COG0822	iron-sulfur transferase activity
FORC2_RS05485	COG0316	Belongs to the HesB IscA family
FORC2_RS05490	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC2_RS05495	COG0443	Heat shock 70 kDa protein
FORC2_RS05500	COG0633	Ferredoxin
FORC2_RS05505	COG2975	iron-sulfur cluster assembly
FORC2_RS05520	COG3468	outer membrane autotransporter barrel domain protein
FORC2_RS05525	COG3468	outer membrane autotransporter barrel domain protein
FORC2_RS05530	COG2373	Large extracellular alpha-helical protein
FORC2_RS05535	COG4953	penicillin-binding protein 1C
FORC2_RS05545	COG0105	UTP biosynthetic process
FORC2_RS05550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC2_RS05560	COG1426	Protein conserved in bacteria
FORC2_RS05565	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC2_RS05570	COG0124	histidyl-tRNA synthetase
FORC2_RS05575	COG2976	Protein conserved in bacteria
FORC2_RS05580	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC2_RS05590	COG1160	GTP binding
FORC2_RS05600	COG1645	bacterial-type flagellum-dependent swarming motility
FORC2_RS05605	COG1570	exodeoxyribonuclease VII activity
FORC2_RS05610	COG0516	GMP reductase activity
FORC2_RS05610	COG0517	IMP dehydrogenase activity
FORC2_RS05615	COG0519	Catalyzes the synthesis of GMP from XMP
FORC2_RS05615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC2_RS05650	COG0351	phosphomethylpyrimidine kinase
FORC2_RS05670	COG1349	DNA-binding transcription factor activity
FORC2_RS05675	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS05680	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS05695	COG3730	PTS system glucitol sorbitol-specific
FORC2_RS05700	COG1597	lipid kinase activity
FORC2_RS05705	COG0826	peptidase U32
FORC2_RS05720	COG3422	double-strand break repair
FORC2_RS05725	COG0745	RESPONSE REGULATOR receiver
FORC2_RS05730	COG2205	protein histidine kinase activity
FORC2_RS05735	COG0477	Major facilitator Superfamily
FORC2_RS05745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC2_RS05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS05760	COG0443	Heat shock 70 kDa protein
FORC2_RS05765	COG5001	Diguanylate cyclase
FORC2_RS05765	COG3447	MASE1 domain protein
FORC2_RS05765	COG5002	protein histidine kinase activity
FORC2_RS05770	COG2239	Acts as a magnesium transporter
FORC2_RS05785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC2_RS05790	COG0573	inorganic phosphate transmembrane transporter activity
FORC2_RS05795	COG0581	inorganic phosphate transmembrane transporter activity
FORC2_RS05815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC2_RS05820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC2_RS05825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC2_RS05830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC2_RS05835	COG2233	PERMEase
FORC2_RS05840	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC2_RS05845	COG1393	Belongs to the ArsC family
FORC2_RS05850	COG4783	chaperone-mediated protein folding
FORC2_RS05855	COG0628	permease
FORC2_RS05860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC2_RS05865	COG2716	regulation of RNA biosynthetic process
FORC2_RS05870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC2_RS05875	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FORC2_RS05880	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC2_RS05885	COG2321	neutral zinc metallopeptidase
FORC2_RS05890	COG2707	UPF0756 membrane protein
FORC2_RS05895	COG1444	tRNA N-acetyltransferase activity
FORC2_RS05900	COG0400	carboxylic ester hydrolase activity
FORC2_RS05910	COG1876	peptidase activity
FORC2_RS05915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC2_RS05920	COG1393	Belongs to the ArsC family
FORC2_RS06100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC2_RS06110	COG2197	response regulator
FORC2_RS06120	COG3062	negative regulation of establishment of protein localization
FORC2_RS06125	COG0243	molybdopterin cofactor binding
FORC2_RS06130	COG3043	anaerobic respiration
FORC2_RS06135	COG3005	denitrification pathway
FORC2_RS06140	COG0494	nUDIX hydrolase
FORC2_RS06160	COG1671	Belongs to the UPF0178 family
FORC2_RS06165	COG0408	coproporphyrinogen oxidase activity
FORC2_RS06170	COG0456	acetyltransferase
FORC2_RS06180	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC2_RS06190	COG2837	iron assimilation
FORC2_RS06195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC2_RS06210	COG2731	YhcH YjgK YiaL family protein
FORC2_RS06215	COG1737	Transcriptional regulator
FORC2_RS06225	COG4150	thiosulfate binding
FORC2_RS06230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FORC2_RS06235	COG4208	sulfate ABC transporter
FORC2_RS06255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS06260	COG0745	RESPONSE REGULATOR receiver
FORC2_RS06265	COG2205	protein histidine kinase activity
FORC2_RS06275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC2_RS06280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS06300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC2_RS06305	COG3530	Putative quorum-sensing-regulated virulence factor
FORC2_RS06335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC2_RS06360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC2_RS06365	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC2_RS06375	COG0667	Aldo Keto reductase
FORC2_RS06380	COG3961	Belongs to the TPP enzyme family
FORC2_RS06395	COG0837	glucose binding
FORC2_RS06400	COG2223	nitrite transmembrane transporter activity
FORC2_RS06405	COG3279	Response regulator of the LytR AlgR family
FORC2_RS06410	COG3275	phosphorelay sensor kinase activity
FORC2_RS06425	COG0436	Aminotransferase
FORC2_RS06430	COG3038	cytochrome b561
FORC2_RS06435	COG1598	PFAM Uncharacterised protein family UPF0150
FORC2_RS06450	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS06460	COG1280	lysine exporter protein (LysE YggA)
FORC2_RS06480	COG2951	lytic endotransglycosylase activity
FORC2_RS06485	COG0531	amino acid
FORC2_RS06505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC2_RS06510	COG1127	ABC transporter
FORC2_RS06530	COG2755	lipolytic protein G-D-S-L family
FORC2_RS06530	COG0657	acetylesterase activity
FORC2_RS06535	COG3038	cytochrome b561
FORC2_RS06540	COG2353	YceI-like domain
FORC2_RS06545	COG1609	Transcriptional regulator
FORC2_RS06550	COG1263	PTS System
FORC2_RS06550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS06555	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS06565	COG1695	Transcriptional regulator
FORC2_RS06570	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC2_RS06660	COG3210	domain, Protein
FORC2_RS06665	COG2831	hemolysin activation secretion protein
FORC2_RS06675	COG3121	Chaperone
FORC2_RS06685	COG3121	Chaperone
FORC2_RS06695	COG3188	usher protein
FORC2_RS06715	COG4977	sequence-specific DNA binding
FORC2_RS06755	COG2116	formate transmembrane transporter activity
FORC2_RS06765	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC2_RS06770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC2_RS06775	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC2_RS06780	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC2_RS06785	COG1138	Cytochrome C-type biogenesis protein
FORC2_RS06790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC2_RS06800	COG3088	subunit of a heme lyase
FORC2_RS06800	COG4235	cytochrome complex assembly
FORC2_RS06825	COG3691	Protein conserved in bacteria
FORC2_RS06830	COG0183	Belongs to the thiolase family
FORC2_RS06835	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC2_RS06835	COG1024	Enoyl-CoA hydratase
FORC2_RS06840	COG2062	phosphohistidine phosphatase, SixA
FORC2_RS06845	COG2840	Smr protein MutS2
FORC2_RS06850	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC2_RS06855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC2_RS06860	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FORC2_RS06865	COG0730	response to heat
FORC2_RS06870	COG3101	peptidyl-lysine hydroxylation
FORC2_RS06880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC2_RS06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC2_RS06885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC2_RS06895	COG1794	racemase activity, acting on amino acids and derivatives
FORC2_RS06905	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC2_RS06910	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS06915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC2_RS06925	COG1609	Transcriptional regulator
FORC2_RS06935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC2_RS06960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC2_RS06965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC2_RS06970	COG0697	spore germination
FORC2_RS06975	COG0697	spore germination
FORC2_RS06985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC2_RS06990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC2_RS07000	COG0586	Pfam SNARE associated Golgi protein
FORC2_RS07005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC2_RS07010	COG0285	dihydrofolate synthase activity
FORC2_RS07015	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC2_RS07020	COG1286	toxin biosynthetic process
FORC2_RS07025	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC2_RS07030	COG0163	prenyltransferase activity
FORC2_RS07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS07040	COG4215	(ABC) transporter
FORC2_RS07045	COG4160	amino acid transport
FORC2_RS07050	COG4598	ABC transporter
FORC2_RS07055	COG1090	epimerase
FORC2_RS07065	COG0622	Phosphoesterase
FORC2_RS07070	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FORC2_RS07075	COG3037	sugar-specific permease SgaT UlaA
FORC2_RS07085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS07090	COG1609	Transcriptional regulator
FORC2_RS07095	COG0857	belongs to the CobB CobQ family
FORC2_RS07095	COG0280	phosphate acetyltransferase
FORC2_RS07105	COG3092	negative regulation of chromosome organization
FORC2_RS07110	COG3013	Belongs to the UPF0304 family
FORC2_RS07115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC2_RS07125	COG0471	metal ion transport
FORC2_RS07125	COG0490	domain, Protein
FORC2_RS07130	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC2_RS07140	COG0436	Aminotransferase
FORC2_RS07145	COG0583	DNA-binding transcription factor activity
FORC2_RS07150	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS07155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS07160	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS07160	COG0649	NAD binding
FORC2_RS07175	COG1034	ATP synthesis coupled electron transport
FORC2_RS07180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FORC2_RS07185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS07190	COG0839	Belongs to the complex I subunit 6 family
FORC2_RS07195	COG0713	ATP synthesis coupled electron transport
FORC2_RS07200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC2_RS07205	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS07210	COG1007	ATP synthesis coupled electron transport
FORC2_RS07240	COG3265	gluconokinase activity
FORC2_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS07250	COG1609	Transcriptional regulator
FORC2_RS07255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC2_RS07265	COG4702	Belongs to the UPF0303 family
FORC2_RS07270	COG0129	dihydroxy-acid dehydratase activity
FORC2_RS07275	COG4575	ribosome binding
FORC2_RS07280	COG1169	isochorismate synthase
FORC2_RS07285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC2_RS07290	COG0596	Alpha beta hydrolase
FORC2_RS07295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC2_RS07300	COG1441	menaquinone biosynthetic process
FORC2_RS07320	COG0814	amino acid
FORC2_RS07340	COG4574	serine-type endopeptidase inhibitor activity
FORC2_RS07345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC2_RS07355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC2_RS07360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC2_RS07370	COG2205	protein histidine kinase activity
FORC2_RS07370	COG0784	Response regulator, receiver
FORC2_RS07380	COG0642	Histidine kinase
FORC2_RS07380	COG2198	Histidine kinase
FORC2_RS07385	COG2223	nitrite transmembrane transporter activity
FORC2_RS07400	COG1132	(ABC) transporter
FORC2_RS07410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC2_RS07425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC2_RS07470	COG1737	Transcriptional regulator
FORC2_RS07475	COG1263	PTS System
FORC2_RS07475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS07475	COG2190	(PTS) system
FORC2_RS07480	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS07505	COG3082	Protein of unknown function (DUF1414)
FORC2_RS07510	COG3081	Nucleoid-associated protein
FORC2_RS07520	COG1061	Type III restriction enzyme res subunit
FORC2_RS07525	COG1187	pseudouridine synthase activity
FORC2_RS07530	COG2814	Major facilitator Superfamily
FORC2_RS07540	COG4172	Belongs to the ABC transporter superfamily
FORC2_RS07545	COG4239	(ABC) transporter, permease
FORC2_RS07550	COG4174	ABC transporter (Permease)
FORC2_RS07555	COG4166	transmembrane transport
FORC2_RS07560	COG2200	EAL domain
FORC2_RS07570	COG0791	NLP P60 protein
FORC2_RS07575	COG0671	phosphoesterase, PA-phosphatase related
FORC2_RS07580	COG0523	cobalamin synthesis protein
FORC2_RS07590	COG2186	Transcriptional regulator
FORC2_RS07595	COG0246	Mannitol dehydrogenase
FORC2_RS07605	COG1312	Catalyzes the dehydration of D-mannonate
FORC2_RS07610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC2_RS07625	COG0243	molybdopterin cofactor binding
FORC2_RS07630	COG3005	denitrification pathway
FORC2_RS07645	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC2_RS07650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC2_RS07650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC2_RS07650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC2_RS07655	COG3710	Transcriptional regulator
FORC2_RS07680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC2_RS07685	COG2855	membrane
FORC2_RS07695	COG0583	DNA-binding transcription factor activity
FORC2_RS07700	COG0833	amino acid
FORC2_RS07705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC2_RS07715	COG4771	TonB-dependent receptor
FORC2_RS07720	COG0625	glutathione transferase activity
FORC2_RS07745	COG2011	ABC-type metal ion transport system permease component
FORC2_RS07760	COG0626	cystathionine gamma-synthase activity
FORC2_RS07770	COG1686	Belongs to the peptidase S11 family
FORC2_RS07775	COG1760	l-serine dehydratase
FORC2_RS07780	COG0814	amino acid
FORC2_RS07785	COG1349	DNA-binding transcription factor activity
FORC2_RS07790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC2_RS07795	COG0671	phosphoesterase, PA-phosphatase related
FORC2_RS07805	COG0569	domain protein
FORC2_RS07805	COG2985	domain, Protein
FORC2_RS07825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC2_RS07830	COG3842	ATPase activity
FORC2_RS07835	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC2_RS07840	COG1177	transmembrane transport
FORC2_RS07850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC2_RS07855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS07865	COG4160	amino acid transport
FORC2_RS07870	COG4215	(ABC) transporter
FORC2_RS07875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS07880	COG1126	abc transporter atp-binding protein
FORC2_RS07890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC2_RS07895	COG0702	epimerase
FORC2_RS07900	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC2_RS07910	COG0028	Belongs to the TPP enzyme family
FORC2_RS07915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC2_RS07920	COG1151	hydroxylamine reductase activity
FORC2_RS07925	COG2431	L-lysine efflux transmembrane transporter activity
FORC2_RS07930	COG3593	DNA synthesis involved in DNA repair
FORC2_RS07935	COG2990	Protein conserved in bacteria
FORC2_RS07940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS07950	COG1278	Cold shock
FORC2_RS07955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC2_RS07960	COG0542	response to heat
FORC2_RS07965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC2_RS07970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC2_RS07975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC2_RS07985	COG0492	ferredoxin-NADP+ reductase activity
FORC2_RS07990	COG1522	sequence-specific DNA binding
FORC2_RS07995	COG3107	peptidoglycan biosynthetic process
FORC2_RS07995	COG1674	ftsk spoiiie
FORC2_RS08000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC2_RS08005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC2_RS08010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC2_RS08015	COG2814	Major facilitator Superfamily
FORC2_RS08020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC2_RS08025	COG1882	Formate acetyltransferase
FORC2_RS08030	COG2116	formate transmembrane transporter activity
FORC2_RS08035	COG1944	ATP diphosphatase activity
FORC2_RS08040	COG0252	asparaginase activity
FORC2_RS08045	COG2323	membrane
FORC2_RS08050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC2_RS08055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC2_RS08060	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC2_RS08065	COG0539	negative regulation of cytoplasmic translation
FORC2_RS08070	COG0776	regulation of translation
FORC2_RS08075	COG0658	competence protein
FORC2_RS08075	COG2333	competence protein COMEC
FORC2_RS08085	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC2_RS08090	COG5383	Protein conserved in bacteria
FORC2_RS08100	COG1278	Cold shock
FORC2_RS08105	COG2835	tetraacyldisaccharide 4'-kinase activity
FORC2_RS08110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC2_RS08115	COG3173	Aminoglycoside phosphotransferase
FORC2_RS08120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC2_RS08125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC2_RS08130	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC2_RS08140	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC2_RS08145	COG2989	Protein conserved in bacteria
FORC2_RS08150	COG3108	Peptidase M15
FORC2_RS08155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC2_RS08160	COG2200	EAL domain
FORC2_RS08165	COG1448	Aminotransferase
FORC2_RS08175	COG0017	Asparaginyl-tRNA synthetase
FORC2_RS08180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC2_RS08185	COG0308	aminopeptidase N
FORC2_RS08190	COG0167	dihydroorotate dehydrogenase activity
FORC2_RS08200	COG3217	Mosc domain protein beta barrel domain protein
FORC2_RS08200	COG0633	Ferredoxin
FORC2_RS08205	COG0116	Belongs to the methyltransferase superfamily
FORC2_RS08205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC2_RS08210	COG0488	(ABC) transporter
FORC2_RS08215	COG2995	paraquat-inducible protein a
FORC2_RS08220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC2_RS08220	COG3008	intermembrane lipid transfer
FORC2_RS08225	COG3009	Protein conserved in bacteria
FORC2_RS08230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC2_RS08240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC2_RS08245	COG1067	ATP-dependent peptidase activity
FORC2_RS08250	COG3120	sequence-specific DNA binding
FORC2_RS08260	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FORC2_RS08265	COG3070	regulator of competence-specific genes
FORC2_RS08270	COG1289	transmembrane transporter activity
FORC2_RS08275	COG3304	Inner membrane component domain
FORC2_RS08280	COG0210	DNA helicase
FORC2_RS08285	COG1803	Methylglyoxal synthase
FORC2_RS08295	COG1832	CoA-binding protein
FORC2_RS08300	COG3785	DNA binding
FORC2_RS08305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC2_RS08320	COG1254	Belongs to the acylphosphatase family
FORC2_RS08325	COG2920	part of a sulfur-relay system
FORC2_RS08345	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC2_RS08350	COG0437	4 iron, 4 sulfur cluster binding
FORC2_RS08355	COG3301	Polysulphide reductase, NrfD
FORC2_RS08360	COG1138	Cytochrome C-type biogenesis protein
FORC2_RS08370	COG3088	subunit of a heme lyase
FORC2_RS08375	COG4235	cytochrome complex assembly
FORC2_RS08380	COG2771	luxR family
FORC2_RS08385	COG3916	Acyl-homoserine-lactone synthase
FORC2_RS08395	COG3263	regulation of cellular component size
FORC2_RS08410	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FORC2_RS08415	COG2943	transferase activity, transferring hexosyl groups
FORC2_RS08420	COG5645	(Lipo)protein
FORC2_RS08435	COG2814	Major facilitator Superfamily
FORC2_RS08440	COG2259	Doxx family
FORC2_RS08445	COG1560	Kdo2-lipid A biosynthetic process
FORC2_RS08480	COG1054	Belongs to the UPF0176 family
FORC2_RS08485	COG0628	permease
FORC2_RS08510	COG0418	dihydroorotase activity
FORC2_RS08515	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC2_RS08520	COG1530	ribonuclease E activity
FORC2_RS08520	COG1530	ribonuclease E activity
FORC2_RS08525	COG0564	pseudouridine synthase activity
FORC2_RS08530	COG0424	maF-like protein
FORC2_RS08535	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC2_RS08540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC2_RS08545	COG0416	fatty acid biosynthetic process
FORC2_RS08550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC2_RS08555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC2_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS08570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC2_RS08575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC2_RS08580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC2_RS08585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC2_RS08590	COG0470	DNA polymerase III
FORC2_RS08595	COG0084	hydrolase, TatD family'
FORC2_RS08600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS08600	COG1263	PTS System
FORC2_RS08610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC2_RS08615	COG0537	adenosine 5'-monophosphoramidase activity
FORC2_RS08620	COG5633	Lipoprotein
FORC2_RS08625	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FORC2_RS08635	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC2_RS08640	COG3150	esterase
FORC2_RS08645	COG1252	NADH dehydrogenase
FORC2_RS08650	COG3134	Outer membrane lipoprotein
FORC2_RS08655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC2_RS08660	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC2_RS08670	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC2_RS08680	COG1940	carbohydrate kinase activity
FORC2_RS08695	COG2850	peptidyl-arginine hydroxylation
FORC2_RS08705	COG0745	RESPONSE REGULATOR receiver
FORC2_RS08715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC2_RS08720	COG2915	High frequency lysogenization protein hflD homolog
FORC2_RS08725	COG0482	sulfurtransferase activity
FORC2_RS08735	COG1187	pseudouridine synthase activity
FORC2_RS08740	COG0538	isocitrate dehydrogenase activity
FORC2_RS08805	COG3772	lysozyme
FORC2_RS08825	COG2873	o-acetylhomoserine
FORC2_RS08830	COG0702	epimerase
FORC2_RS08835	COG1733	regulation of RNA biosynthetic process
FORC2_RS08855	COG0765	amino acid transport
FORC2_RS08860	COG0765	amino acid transport
FORC2_RS08865	COG1126	abc transporter atp-binding protein
FORC2_RS08870	COG2721	sulfolactate sulfo-lyase activity
FORC2_RS08875	COG0246	Mannitol dehydrogenase
FORC2_RS08880	COG1063	alcohol dehydrogenase
FORC2_RS08885	COG1802	Transcriptional regulator
FORC2_RS08890	COG4948	Mandelate Racemase Muconate Lactonizing
FORC2_RS08900	COG2271	Major facilitator Superfamily
FORC2_RS08915	COG3755	Protein conserved in bacteria
FORC2_RS08930	COG5001	Diguanylate cyclase
FORC2_RS08930	COG3706	GGDEF domain
FORC2_RS08930	COG2203	Gaf domain
FORC2_RS08930	COG4251	negative regulation of phosphorylation
FORC2_RS08950	COG1132	(ABC) transporter
FORC2_RS08975	COG2207	Transcriptional regulator
FORC2_RS09010	COG1113	amino acid transport
FORC2_RS09030	COG1496	oxidoreductase activity
FORC2_RS09035	COG0768	penicillin binding
FORC2_RS09040	COG2226	methyltransferase
FORC2_RS09050	COG5002	protein histidine kinase activity
FORC2_RS09050	COG5001	Diguanylate cyclase
FORC2_RS09050	COG3447	MASE1 domain protein
FORC2_RS09060	COG1971	Probably functions as a manganese efflux pump
FORC2_RS09065	COG4811	Protein of unknown function (DUF986)
FORC2_RS09070	COG3716	PTS system mannose fructose sorbose family IID component
FORC2_RS09075	COG3715	PTS system
FORC2_RS09080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS09080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS09085	COG1253	flavin adenine dinucleotide binding
FORC2_RS09090	COG1760	l-serine dehydratase
FORC2_RS09095	COG0494	nUDIX hydrolase
FORC2_RS09105	COG3140	Belongs to the UPF0181 family
FORC2_RS09110	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC2_RS09115	COG0513	Belongs to the DEAD box helicase family
FORC2_RS09120	COG3141	response to X-ray
FORC2_RS09125	COG3097	Belongs to the UPF0267 family
FORC2_RS09135	COG1770	oligopeptidase
FORC2_RS09140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC2_RS09155	COG1528	Iron-storage protein
FORC2_RS09160	COG2372	response to copper ion
FORC2_RS09165	COG1276	copper resistance
FORC2_RS09175	COG0582	viral genome integration into host DNA
FORC2_RS09260	COG2826	transposase and inactivated derivatives, IS30 family
FORC2_RS09315	COG0488	(ABC) transporter
FORC2_RS09350	COG3772	lysozyme
FORC2_RS09355	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC2_RS09360	COG2979	Protein of unknown function (DUF533)
FORC2_RS09375	COG2186	Transcriptional regulator
FORC2_RS09380	COG3734	2-keto-3-deoxy-galactonokinase
FORC2_RS09385	COG0800	Aldolase
FORC2_RS09390	COG4948	Mandelate Racemase Muconate Lactonizing
FORC2_RS09400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC2_RS09405	COG0012	GTP binding
FORC2_RS09415	COG0193	aminoacyl-tRNA hydrolase activity
FORC2_RS09425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC2_RS09435	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC2_RS09440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC2_RS09445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC2_RS09450	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC2_RS09465	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC2_RS09470	COG0659	secondary active sulfate transmembrane transporter activity
FORC2_RS09475	COG3706	GGDEF domain
FORC2_RS09495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC2_RS09500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC2_RS09505	COG3381	protein complex oligomerization
FORC2_RS09515	COG0477	Major facilitator Superfamily
FORC2_RS09540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC2_RS09550	COG0673	inositol 2-dehydrogenase activity
FORC2_RS09555	COG0728	peptidoglycan biosynthetic process
FORC2_RS09560	COG0018	arginyl-trna synthetase
FORC2_RS09565	COG3102	Protein conserved in bacteria
FORC2_RS09570	COG3142	Participates in the control of copper homeostasis
FORC2_RS09575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC2_RS09580	COG2226	methyltransferase
FORC2_RS09585	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FORC2_RS09590	COG1801	Protein of unknown function DUF72
FORC2_RS09595	COG1335	isochorismatase
FORC2_RS09600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC2_RS09605	COG0494	nUDIX hydrolase
FORC2_RS09610	COG0217	transcriptional regulatory protein
FORC2_RS09615	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC2_RS09620	COG0632	four-way junction helicase activity
FORC2_RS09625	COG2255	four-way junction helicase activity
FORC2_RS09630	COG3104	oligopeptide transport
FORC2_RS09635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC2_RS09640	COG1121	(ABC) transporter
FORC2_RS09645	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC2_RS09650	COG0739	heme binding
FORC2_RS09655	COG1560	Kdo2-lipid A biosynthetic process
FORC2_RS09660	COG0469	pyruvate kinase activity
FORC2_RS09665	COG1737	Transcriptional regulator
FORC2_RS09670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC2_RS09675	COG0800	Aldolase
FORC2_RS09680	COG2076	Multidrug Resistance protein
FORC2_RS09685	COG2076	Multidrug Resistance protein
FORC2_RS09690	COG0251	oxidation-reduction process
FORC2_RS09695	COG1199	ATP-dependent helicase activity
FORC2_RS09705	COG3065	identical protein binding
FORC2_RS09710	COG0318	PFAM AMP-dependent synthetase and ligase
FORC2_RS09715	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC2_RS09720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC2_RS09725	COG2894	cell division
FORC2_RS09730	COG0850	regulation of cytokinetic process
FORC2_RS09740	COG3100	YcgL domain-containing protein
FORC2_RS09745	COG2951	lytic endotransglycosylase activity
FORC2_RS09750	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC2_RS09755	COG2983	Belongs to the UPF0260 family
FORC2_RS09765	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC2_RS09770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC2_RS09775	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC2_RS09780	COG2186	Transcriptional regulator
FORC2_RS09785	COG2719	SpoVR family
FORC2_RS09790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC2_RS09795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC2_RS09800	COG2814	Major facilitator Superfamily
FORC2_RS09805	COG2202	Pas domain
FORC2_RS09805	COG2200	EAL domain
FORC2_RS09805	COG2199	diguanylate cyclase activity
FORC2_RS09815	COG0583	DNA-binding transcription factor activity
FORC2_RS09830	COG2718	Belongs to the UPF0229 family
FORC2_RS09835	COG2766	serine protein kinase
FORC2_RS09840	COG3713	MltA-interacting MipA family protein
FORC2_RS09855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC2_RS09860	COG3139	Protein of unknown function (DUF1315)
FORC2_RS09865	COG1335	isochorismatase
FORC2_RS09870	COG0252	asparaginase activity
FORC2_RS09875	COG0616	signal peptide processing
FORC2_RS09880	COG0778	Nitroreductase
FORC2_RS09890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC2_RS09900	COG0494	nUDIX hydrolase
FORC2_RS09905	COG0708	Exodeoxyribonuclease III
FORC2_RS09910	COG0583	DNA-binding transcription factor activity
FORC2_RS09925	COG0788	formyltetrahydrofolate deformylase activity
FORC2_RS09930	COG3012	SEC-C Motif Domain Protein
FORC2_RS09940	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC2_RS09945	COG0745	RESPONSE REGULATOR receiver
FORC2_RS09955	COG2916	Histone family protein nucleoid-structuring protein H-NS
FORC2_RS09970	COG1454	alcohol dehydrogenase
FORC2_RS09970	COG1012	belongs to the aldehyde dehydrogenase family
FORC2_RS09975	COG2095	MarC family integral membrane protein
FORC2_RS09995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC2_RS10000	COG0444	Belongs to the ABC transporter superfamily
FORC2_RS10010	COG3099	Belongs to the UPF0263 family
FORC2_RS10015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC2_RS10030	COG2350	Protein conserved in bacteria
FORC2_RS10035	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC2_RS10045	COG2917	probably involved in intracellular septation
FORC2_RS10060	COG0727	PFAM Uncharacterised protein family (UPF0153)
FORC2_RS10065	COG3047	cAMP biosynthetic process
FORC2_RS10075	COG0159	tryptophan synthase activity
FORC2_RS10080	COG0133	tryptophan synthase activity
FORC2_RS10085	COG0135	phosphoribosylanthranilate isomerase activity
FORC2_RS10085	COG0134	indole-3-glycerol-phosphate synthase activity
FORC2_RS10095	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC2_RS10105	COG0613	PHP domain protein
FORC2_RS10110	COG0009	L-threonylcarbamoyladenylate synthase
FORC2_RS10115	COG1187	pseudouridine synthase activity
FORC2_RS10125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC2_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS10135	COG0616	signal peptide processing
FORC2_RS10150	COG0583	DNA-binding transcription factor activity
FORC2_RS10205	COG4974	Belongs to the 'phage' integrase family
FORC2_RS10220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC2_RS10230	COG0671	phosphoesterase, PA-phosphatase related
FORC2_RS10235	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC2_RS10240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC2_RS10250	COG1396	sequence-specific DNA binding
FORC2_RS10255	COG3135	benzoate transporter
FORC2_RS10265	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC2_RS10270	COG0023	Translation Initiation Factor
FORC2_RS10280	COG0235	Class ii aldolase
FORC2_RS10290	COG1349	DNA-binding transcription factor activity
FORC2_RS10295	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC2_RS10300	COG2879	small protein
FORC2_RS10305	COG1966	Carbon starvation protein
FORC2_RS10310	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC2_RS10315	COG0243	molybdopterin cofactor binding
FORC2_RS10330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC2_RS10340	COG4659	FMN binding
FORC2_RS10345	COG4658	electron transport chain
FORC2_RS10350	COG2207	Transcriptional regulator
FORC2_RS10350	COG3708	Transcriptional regulator
FORC2_RS10355	COG4656	Part of a membrane complex involved in electron transport
FORC2_RS10365	COG4657	Part of a membrane complex involved in electron transport
FORC2_RS10375	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC2_RS10395	COG2160	L-arabinose isomerase activity
FORC2_RS10405	COG1879	ABC-type sugar transport system periplasmic component
FORC2_RS10410	COG1129	ABC transporter
FORC2_RS10415	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS10425	COG0673	inositol 2-dehydrogenase activity
FORC2_RS10430	COG0385	Bile acid
FORC2_RS10435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC2_RS10440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC2_RS10445	COG1263	PTS System
FORC2_RS10445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS10450	COG1609	Transcriptional regulator
FORC2_RS10460	COG5339	Protein conserved in bacteria
FORC2_RS10470	COG0114	fumarate hydratase activity
FORC2_RS10495	COG2814	Major facilitator Superfamily
FORC2_RS10500	COG0583	DNA-binding transcription factor activity
FORC2_RS10505	COG1940	carbohydrate kinase activity
FORC2_RS10510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC2_RS10545	COG1742	UPF0060 membrane protein
FORC2_RS10550	COG4221	oxidoreductase activity
FORC2_RS10555	COG0477	Major facilitator Superfamily
FORC2_RS10590	COG0625	glutathione transferase activity
FORC2_RS10610	COG3604	Transcriptional regulator
FORC2_RS10615	COG1773	rubredoxin
FORC2_RS10615	COG0426	domain, Protein
FORC2_RS10620	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC2_RS10630	COG1522	sequence-specific DNA binding
FORC2_RS10655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC2_RS10665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC2_RS10675	COG0483	inositol monophosphate 1-phosphatase activity
FORC2_RS10680	COG2271	Major facilitator Superfamily
FORC2_RS10700	COG0028	Belongs to the TPP enzyme family
FORC2_RS10705	COG0440	acetolactate synthase activity
FORC2_RS10710	COG1011	Hydrolase
FORC2_RS10730	COG0738	Major facilitator superfamily
FORC2_RS10735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC2_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS10755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FORC2_RS10770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC2_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC2_RS10780	COG0589	response to stress
FORC2_RS10785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC2_RS10790	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC2_RS10805	COG0531	amino acid
FORC2_RS10815	COG0745	RESPONSE REGULATOR receiver
FORC2_RS10820	COG2205	protein histidine kinase activity
FORC2_RS10825	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC2_RS10835	COG3591	Belongs to the peptidase S1B family
FORC2_RS10850	COG1643	Atp-dependent helicase
FORC2_RS10855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC2_RS10865	COG0246	Mannitol dehydrogenase
FORC2_RS10870	COG1070	Carbohydrate kinase
FORC2_RS10880	COG3784	Protein of unknown function (DUF1318)
FORC2_RS10890	COG2911	Protein conserved in bacteria
FORC2_RS10895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC2_RS10900	COG3042	response to heat
FORC2_RS10905	COG1285	pathogenesis
FORC2_RS10915	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC2_RS10915	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC2_RS10915	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC2_RS10915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS10920	COG2723	6-phospho-beta-galactosidase activity
FORC2_RS10925	COG2190	(PTS) system
FORC2_RS10925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS10925	COG1263	PTS System
FORC2_RS10930	COG3711	transcriptional antiterminator
FORC2_RS10935	COG0037	tRNA processing
FORC2_RS10940	COG0598	Magnesium transport protein CorA
FORC2_RS10955	COG4166	transmembrane transport
FORC2_RS10960	COG2866	Carboxypeptidase
FORC2_RS10965	COG4948	Mandelate Racemase Muconate Lactonizing
FORC2_RS10970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC2_RS10980	COG5642	Protein of unknown function (DUF2384)
FORC2_RS10985	COG5654	RES domain protein
FORC2_RS10990	COG3768	UPF0283 membrane protein
FORC2_RS10995	COG3106	COG3106 Predicted ATPase
FORC2_RS11005	COG1983	PspC domain protein
FORC2_RS11015	COG1842	Phage shock protein A
FORC2_RS11020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC2_RS11035	COG4166	transmembrane transport
FORC2_RS11045	COG4171	peptide transport system, permease
FORC2_RS11055	COG4172	Belongs to the ABC transporter superfamily
FORC2_RS11065	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC2_RS11065	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC2_RS11075	COG3104	oligopeptide transport
FORC2_RS11105	COG0625	glutathione transferase activity
FORC2_RS11115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC2_RS11120	COG0259	pyridoxamine-phosphate oxidase activity
FORC2_RS11125	COG3895	Periplasmic Protein
FORC2_RS11130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC2_RS11135	COG3133	Outer membrane lipoprotein
FORC2_RS11140	COG1846	Transcriptional regulator
FORC2_RS11150	COG1566	PFAM secretion protein HlyD family protein
FORC2_RS11155	COG1289	transmembrane transporter activity
FORC2_RS11160	COG4989	oxidoreductase activity
FORC2_RS11165	COG3313	Fe-S protein
FORC2_RS11170	COG2194	sulfuric ester hydrolase activity
FORC2_RS11175	COG1309	transcriptional regulator
FORC2_RS11180	COG1902	pentaerythritol trinitrate reductase activity
FORC2_RS11185	COG0346	lactoylglutathione lyase activity
FORC2_RS11190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC2_RS11195	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC2_RS11200	COG0791	NLP P60 protein
FORC2_RS11210	COG1609	Transcriptional regulator
FORC2_RS11215	COG0583	DNA-binding transcription factor activity
FORC2_RS11220	COG2814	Major facilitator Superfamily
FORC2_RS11225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC2_RS11230	COG0307	riboflavin synthase, alpha
FORC2_RS11235	COG0534	Mate efflux family protein
FORC2_RS11265	COG1376	ErfK ybiS ycfS ynhG family protein
FORC2_RS11265	COG1388	LysM domain
FORC2_RS11270	COG2166	iron-sulfur cluster assembly
FORC2_RS11280	COG0719	Fe-S assembly protein
FORC2_RS11285	COG0396	ATPase activity
FORC2_RS11290	COG0719	Fe-S assembly protein
FORC2_RS11295	COG0316	Belongs to the HesB IscA family
FORC2_RS11300	COG2050	protein possibly involved in aromatic compounds catabolism
FORC2_RS11305	COG0277	FAD linked oxidase domain protein
FORC2_RS11305	COG0247	lactate metabolic process
FORC2_RS11310	COG0628	permease
FORC2_RS11315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC2_RS11315	COG0574	Belongs to the PEP-utilizing enzyme family
FORC2_RS11320	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC2_RS11335	COG4771	TonB-dependent receptor
FORC2_RS11340	COG3720	iron ion transport
FORC2_RS11345	COG4558	Periplasmic binding protein
FORC2_RS11355	COG0095	Lipoate-protein ligase
FORC2_RS11360	COG0791	NLP P60 protein
FORC2_RS11365	COG2076	Multidrug Resistance protein
FORC2_RS11370	COG2076	Multidrug Resistance protein
FORC2_RS11375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FORC2_RS11380	COG0726	polysaccharide deacetylase
FORC2_RS11385	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC2_RS11385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC2_RS11390	COG0463	Glycosyl transferase, family 2
FORC2_RS11395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC2_RS11400	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC2_RS11405	COG0386	Belongs to the glutathione peroxidase family
FORC2_RS11410	COG4139	cobalamin transport
FORC2_RS11420	COG0776	regulation of translation
FORC2_RS11430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC2_RS11435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FORC2_RS11440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC2_RS11445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FORC2_RS11450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC2_RS11455	COG4249	Peptidase C14 caspase catalytic subunit p20
FORC2_RS11460	COG1811	Na channel or pump
FORC2_RS11495	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC2_RS11500	COG1121	(ABC) transporter
FORC2_RS11505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC2_RS11510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC2_RS11515	COG3001	Fructosamine kinase
FORC2_RS11520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC2_RS11520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FORC2_RS11525	COG1703	isobutyryl-CoA mutase activity
FORC2_RS11530	COG1024	Enoyl-CoA hydratase
FORC2_RS11535	COG0427	acetyl-CoA hydrolase
FORC2_RS11540	COG0583	DNA-binding transcription factor activity
FORC2_RS11550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC2_RS11555	COG1917	Cupin 2, conserved barrel domain protein
FORC2_RS11560	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FORC2_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS11580	COG1175	transmembrane transport
FORC2_RS11585	COG0395	ABC-type sugar transport system, permease component
FORC2_RS11590	COG3842	ATPase activity
FORC2_RS11595	COG1653	transport
FORC2_RS11600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC2_RS11610	COG1988	membrane-bound metal-dependent
FORC2_RS11615	COG1823	symporter activity
FORC2_RS11620	COG3023	N-Acetylmuramoyl-L-alanine amidase
FORC2_RS11630	COG0823	Involved in the tonB-independent uptake of proteins
FORC2_RS11635	COG2814	Major facilitator Superfamily
FORC2_RS11660	COG0501	Belongs to the peptidase M48B family
FORC2_RS11665	COG0793	Belongs to the peptidase S41A family
FORC2_RS11675	COG1956	GAF domain-containing protein
FORC2_RS11680	COG2995	paraquat-inducible protein a
FORC2_RS11685	COG3008	intermembrane lipid transfer
FORC2_RS11695	COG2814	Major facilitator Superfamily
FORC2_RS11730	COG5001	Diguanylate cyclase
FORC2_RS11730	COG3706	GGDEF domain
FORC2_RS11730	COG4251	negative regulation of phosphorylation
FORC2_RS11730	COG2203	Gaf domain
FORC2_RS11755	COG0625	glutathione transferase activity
FORC2_RS11760	COG0668	transmembrane transport
FORC2_RS11780	COG0786	glutamate:sodium symporter activity
FORC2_RS11785	COG1187	pseudouridine synthase activity
FORC2_RS11800	COG1349	DNA-binding transcription factor activity
FORC2_RS11810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS11820	COG3716	PTS system mannose fructose sorbose family IID component
FORC2_RS11825	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS11830	COG2222	sugar isomerase
FORC2_RS11840	COG4942	peptidase
FORC2_RS11850	COG3443	Belongs to the bacterial solute-binding protein 9 family
FORC2_RS11860	COG0402	S-adenosylhomocysteine deaminase activity
FORC2_RS11870	COG1228	amidohydrolase
FORC2_RS11885	COG2988	succinylglutamate desuccinylase activity
FORC2_RS11890	COG3724	N-succinylarginine dihydrolase activity
FORC2_RS11900	COG3138	arginine N-succinyltransferase
FORC2_RS11905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC2_RS11910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC2_RS11915	COG1271	oxidase subunit
FORC2_RS11920	COG1294	oxidase, subunit
FORC2_RS11925	COG3850	Histidine kinase
FORC2_RS11930	COG0583	DNA-binding transcription factor activity
FORC2_RS11935	COG2814	Major facilitator Superfamily
FORC2_RS11945	COG0387	Pfam Sodium calcium exchanger
FORC2_RS11950	COG1702	phosphate starvation-inducible protein PhoH
FORC2_RS11965	COG3658	cytochrome
FORC2_RS11970	COG1215	transferase activity, transferring glycosyl groups
FORC2_RS11975	COG0726	polysaccharide deacetylase
FORC2_RS11975	COG1649	PFAM Uncharacterised BCR, COG1649
FORC2_RS11980	COG0457	Tetratricopeptide repeat
FORC2_RS11985	COG0006	proline dipeptidase activity
FORC2_RS11990	COG4114	ferric iron reductase
FORC2_RS11995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC2_RS12020	COG1136	(ABC) transporter
FORC2_RS12020	COG0577	efflux transmembrane transporter activity
FORC2_RS12030	COG0577	efflux transmembrane transporter activity
FORC2_RS12030	COG1136	(ABC) transporter
FORC2_RS12045	COG0672	)-iron permease
FORC2_RS12060	COG2066	Belongs to the glutaminase family
FORC2_RS12065	COG3622	Belongs to the hyi family
FORC2_RS12070	COG0235	Class ii aldolase
FORC2_RS12075	COG3395	kinase activity
FORC2_RS12080	COG1349	DNA-binding transcription factor activity
FORC2_RS12085	COG3290	protein histidine kinase activity
FORC2_RS12090	COG4565	transcriptional regulatory protein
FORC2_RS12095	COG3493	citrate carrier protein
FORC2_RS12115	COG0346	lactoylglutathione lyase activity
FORC2_RS12125	COG2223	nitrite transmembrane transporter activity
FORC2_RS12130	COG0561	phosphatase activity
FORC2_RS12145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC2_RS12235	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC2_RS12325	COG3772	lysozyme
FORC2_RS12380	COG0305	Participates in initiation and elongation during chromosome replication
FORC2_RS12460	COG4974	Belongs to the 'phage' integrase family
FORC2_RS12530	COG4695	Portal protein
FORC2_RS12680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC2_RS12685	COG0322	excinuclease ABC activity
FORC2_RS12690	COG2197	response regulator
FORC2_RS12700	COG3136	membrane protein required for alginate biosynthesis
FORC2_RS12710	COG0366	Alpha amylase catalytic
FORC2_RS12725	COG2226	methyltransferase
FORC2_RS12745	COG1113	amino acid transport
FORC2_RS12750	COG1309	transcriptional regulator
FORC2_RS12755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC2_RS12760	COG1335	isochorismatase
FORC2_RS12765	COG0251	oxidation-reduction process
FORC2_RS12770	COG2267	carboxylic ester hydrolase activity
FORC2_RS12775	COG0778	Nitroreductase
FORC2_RS12780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC2_RS12785	COG2233	PERMEase
FORC2_RS12790	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FORC2_RS12800	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC2_RS12810	COG2822	iron ion transport
FORC2_RS12815	COG0672	)-iron permease
FORC2_RS12825	COG0506	proline dehydrogenase activity
FORC2_RS12825	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FORC2_RS12825	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FORC2_RS12840	COG1126	abc transporter atp-binding protein
FORC2_RS12845	COG0765	amino acid transport
FORC2_RS12850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS12855	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC2_RS12865	COG1191	sigma factor activity
FORC2_RS12915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC2_RS12920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC2_RS12925	COG1677	Flagellar hook-basal body complex protein FliE
FORC2_RS12940	COG1317	bacterial-type flagellum organization
FORC2_RS12960	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC2_RS12980	COG1338	Plays a role in the flagellum-specific transport system
FORC2_RS13000	COG1256	bacterial-type flagellum assembly
FORC2_RS13035	COG1749	Flagellar hook protein flgE
FORC2_RS13040	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC2_RS13045	COG1558	bacterial-type flagellum-dependent cell motility
FORC2_RS13050	COG1815	bacterial-type flagellum-dependent cell motility
FORC2_RS13060	COG2747	anti-sigma28 factor FlgM
FORC2_RS13065	COG3418	PFAM FlgN family protein
FORC2_RS13080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC2_RS13085	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC2_RS13090	COG4935	Belongs to the peptidase S8 family
FORC2_RS13090	COG1404	Belongs to the peptidase S8 family
FORC2_RS13095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC2_RS13100	COG0745	RESPONSE REGULATOR receiver
FORC2_RS13110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC2_RS13115	COG0840	transmembrane signaling receptor activity
FORC2_RS13120	COG0840	transmembrane signaling receptor activity
FORC2_RS13125	COG0835	chemotaxis
FORC2_RS13130	COG0643	Histidine kinase
FORC2_RS13130	COG2198	Histidine kinase
FORC2_RS13135	COG1360	Flagellar Motor Protein
FORC2_RS13155	COG0589	response to stress
FORC2_RS13160	COG2130	NADP-dependent
FORC2_RS13170	COG1285	pathogenesis
FORC2_RS13175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FORC2_RS13180	COG0840	transmembrane signaling receptor activity
FORC2_RS13195	COG1609	Transcriptional regulator
FORC2_RS13200	COG3250	beta-galactosidase activity
FORC2_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS13205	COG3321	synthase
FORC2_RS13205	COG0604	alcohol dehydrogenase
FORC2_RS13235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC2_RS13240	COG3121	Chaperone
FORC2_RS13265	COG1070	Carbohydrate kinase
FORC2_RS13270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC2_RS13280	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS13285	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS13290	COG1129	ABC transporter
FORC2_RS13300	COG3228	Belongs to the MtfA family
FORC2_RS13315	COG3122	Protein conserved in bacteria
FORC2_RS13320	COG0577	efflux transmembrane transporter activity
FORC2_RS13320	COG1136	(ABC) transporter
FORC2_RS13325	COG1136	(ABC) transporter
FORC2_RS13325	COG0577	efflux transmembrane transporter activity
FORC2_RS13350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS13350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS13355	COG2814	Major facilitator Superfamily
FORC2_RS13370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC2_RS13385	COG0471	metal ion transport
FORC2_RS13400	COG3051	citrate lyase alpha subunit
FORC2_RS13405	COG2301	Belongs to the HpcH HpaI aldolase family
FORC2_RS13410	COG3052	prosthetic group binding
FORC2_RS13415	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FORC2_RS13420	COG3290	protein histidine kinase activity
FORC2_RS13425	COG4565	transcriptional regulatory protein
FORC2_RS13440	COG2271	Major facilitator Superfamily
FORC2_RS13445	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC2_RS13455	COG3842	ATPase activity
FORC2_RS13465	COG0582	viral genome integration into host DNA
FORC2_RS13520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS13520	COG2205	protein histidine kinase activity
FORC2_RS13545	COG3121	Chaperone
FORC2_RS13570	COG1063	alcohol dehydrogenase
FORC2_RS13580	COG4214	carbohydrate transport
FORC2_RS13600	COG1129	ABC transporter
FORC2_RS13610	COG4221	oxidoreductase activity
FORC2_RS13620	COG0784	Response regulator, receiver
FORC2_RS13620	COG0835	chemotaxis
FORC2_RS13630	COG1349	DNA-binding transcription factor activity
FORC2_RS13635	COG0561	phosphatase activity
FORC2_RS13640	COG0352	thiamine-phosphate diphosphorylase activity
FORC2_RS13650	COG0534	Mate efflux family protein
FORC2_RS13655	COG0137	argininosuccinate synthase activity
FORC2_RS13725	COG3188	usher protein
FORC2_RS13730	COG3121	Chaperone
FORC2_RS13790	COG2211	Major facilitator Superfamily
FORC2_RS13795	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC2_RS13805	COG0583	DNA-binding transcription factor activity
FORC2_RS13810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC2_RS13830	COG1492	cobalamin metabolic process
FORC2_RS13895	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FORC2_RS13905	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FORC2_RS13980	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FORC2_RS13985	COG2096	Adenosyltransferase
FORC2_RS14000	COG4656	Part of a membrane complex involved in electron transport
FORC2_RS14020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC2_RS14025	COG1648	precorrin-2 dehydrogenase activity
FORC2_RS14025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC2_RS14030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC2_RS14060	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS14070	COG2926	Belongs to the UPF0265 family
FORC2_RS14075	COG1289	transmembrane transporter activity
FORC2_RS14080	COG1022	Amp-dependent synthetase and ligase
FORC2_RS14080	COG3320	Male sterility
FORC2_RS14085	COG2925	Exonuclease
FORC2_RS14090	COG0531	amino acid
FORC2_RS14100	COG0371	Dehydrogenase
FORC2_RS14105	COG1129	ABC transporter
FORC2_RS14115	COG1129	ABC transporter
FORC2_RS14120	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS14125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC2_RS14130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC2_RS14140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC2_RS14145	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC2_RS14145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC2_RS14155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC2_RS14160	COG0107	imidazoleglycerol-phosphate synthase activity
FORC2_RS14165	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC2_RS14165	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC2_RS14170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC2_RS14175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC2_RS14180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC2_RS14185	COG1253	flavin adenine dinucleotide binding
FORC2_RS14190	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC2_RS14195	COG2982	Protein involved in outer membrane biogenesis
FORC2_RS14205	COG0572	uridine kinase
FORC2_RS14210	COG0489	protein tyrosine kinase activity
FORC2_RS14215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC2_RS14215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC2_RS14235	COG2814	Major facilitator Superfamily
FORC2_RS14240	COG1380	Effector of murein hydrolase LrgA
FORC2_RS14245	COG1346	cytolysis
FORC2_RS14260	COG0281	malic enzyme
FORC2_RS14265	COG2949	membrane
FORC2_RS14270	COG0298	carbon dioxide binding
FORC2_RS14275	COG0375	protein maturation
FORC2_RS14280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC2_RS14285	COG0651	ATP synthesis coupled electron transport
FORC2_RS14290	COG0650	Formate hydrogenlyase subunit 4
FORC2_RS14295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC2_RS14300	COG4237	Hydrogenase 4 membrane
FORC2_RS14305	COG0651	ATP synthesis coupled electron transport
FORC2_RS14310	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FORC2_RS14310	COG3261	NADH dehydrogenase
FORC2_RS14315	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC2_RS14320	COG3260	NADH ubiquinone oxidoreductase 20
FORC2_RS14330	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FORC2_RS14335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC2_RS14340	COG3383	formate dehydrogenase (NAD+) activity
FORC2_RS14345	COG3604	Transcriptional regulator
FORC2_RS14350	COG2116	formate transmembrane transporter activity
FORC2_RS14375	COG2311	Membrane
FORC2_RS14380	COG0302	gtp cyclohydrolase
FORC2_RS14385	COG0477	Major facilitator Superfamily
FORC2_RS14390	COG0583	DNA-binding transcription factor activity
FORC2_RS14420	COG0577	efflux transmembrane transporter activity
FORC2_RS14420	COG1136	(ABC) transporter
FORC2_RS14435	COG0303	'Molybdopterin
FORC2_RS14440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC2_RS14445	COG0488	(ABC) transporter
FORC2_RS14465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FORC2_RS14485	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FORC2_RS14500	COG4106	trans-aconitate 2-methyltransferase activity
FORC2_RS14505	COG0783	Belongs to the Dps family
FORC2_RS14510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC2_RS14515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS14520	COG0765	amino acid transport
FORC2_RS14525	COG1126	abc transporter atp-binding protein
FORC2_RS14535	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FORC2_RS14555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC2_RS14560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC2_RS14580	COG0697	spore germination
FORC2_RS14590	COG0583	DNA-binding transcription factor activity
FORC2_RS14605	COG1174	glycine betaine transport
FORC2_RS14610	COG1125	glycine betaine transport
FORC2_RS14615	COG1174	glycine betaine transport
FORC2_RS14620	COG1732	Glycine betaine
FORC2_RS14635	COG2897	thiosulfate sulfurtransferase activity
FORC2_RS14665	COG4807	Protein conserved in bacteria
FORC2_RS14680	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FORC2_RS14690	COG2261	transglycosylase associated protein
FORC2_RS14710	COG0277	FAD linked oxidase domain protein
FORC2_RS14715	COG1686	Belongs to the peptidase S11 family
FORC2_RS14730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC2_RS14735	COG0513	Belongs to the DEAD box helicase family
FORC2_RS14740	COG1309	transcriptional regulator
FORC2_RS14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS14750	COG1131	(ABC) transporter
FORC2_RS14755	COG0842	Transport permease protein
FORC2_RS14760	COG0842	Transport permease protein
FORC2_RS14765	COG0670	Belongs to the BI1 family
FORC2_RS14770	COG0314	molybdopterin synthase activity
FORC2_RS14775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC2_RS14780	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC2_RS14785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC2_RS14790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC2_RS14795	COG4628	conserved protein (DUF2132)
FORC2_RS14800	COG0556	nucleotide-excision repair
FORC2_RS14815	COG2226	methyltransferase
FORC2_RS14820	COG0156	8-amino-7-oxononanoate synthase activity
FORC2_RS14825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC2_RS14835	COG2706	6-phosphogluconolactonase activity
FORC2_RS14840	COG0561	phosphatase activity
FORC2_RS14850	COG4149	molybdate abc transporter
FORC2_RS14855	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC2_RS14865	COG2005	Transcriptional regulator
FORC2_RS14865	COG3585	molybdate ion transport
FORC2_RS14870	COG1119	ATPase activity
FORC2_RS14880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC2_RS14885	COG1085	galactose-1-phosphate uridylyltransferase
FORC2_RS14890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC2_RS14895	COG2017	converts alpha-aldose to the beta-anomer
FORC2_RS14910	COG0588	phosphoglycerate mutase activity
FORC2_RS14915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC2_RS14920	COG1230	cation diffusion facilitator family transporter
FORC2_RS14930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC2_RS14955	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC2_RS14960	COG2885	chlorophyll binding
FORC2_RS14965	COG0823	Involved in the tonB-independent uptake of proteins
FORC2_RS14970	COG3064	Membrane
FORC2_RS14970	COG3064	Membrane
FORC2_RS14975	COG0848	biopolymer transport protein
FORC2_RS14980	COG0811	peptide transport
FORC2_RS14985	COG0824	Thioesterase
FORC2_RS14990	COG3790	cyd operon protein YbgE
FORC2_RS14995	COG4890	Cyd operon protein YbgT
FORC2_RS15000	COG1294	oxidase, subunit
FORC2_RS15005	COG1271	oxidase subunit
FORC2_RS15010	COG0737	Belongs to the 5'-nucleotidase family
FORC2_RS15015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC2_RS15020	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC2_RS15025	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC2_RS15030	COG0567	Dehydrogenase, E1 component
FORC2_RS15040	COG1053	succinate dehydrogenase
FORC2_RS15045	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC2_RS15050	COG2009	succinate dehydrogenase
FORC2_RS15060	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FORC2_RS15075	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC2_RS15080	COG1984	allophanate hydrolase subunit 2
FORC2_RS15085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC2_RS15090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC2_RS15095	COG5212	phosphodiesterase
FORC2_RS15105	COG3272	Protein of unknown function (DUF1722)
FORC2_RS15110	COG1073	alpha beta
FORC2_RS15110	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC2_RS15110	COG1073	alpha beta
FORC2_RS15110	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FORC2_RS15110	COG3064	Membrane
FORC2_RS15110	COG3064	Membrane
FORC2_RS15115	COG2994	toxin metabolic process
FORC2_RS15135	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FORC2_RS15140	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FORC2_RS15145	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FORC2_RS15150	COG2205	protein histidine kinase activity
FORC2_RS15155	COG0745	RESPONSE REGULATOR receiver
FORC2_RS15170	COG0033	Phosphoglucomutase
FORC2_RS15175	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC2_RS15180	COG0596	Alpha beta hydrolase
FORC2_RS15190	COG0840	transmembrane signaling receptor activity
FORC2_RS15200	COG0735	belongs to the Fur family
FORC2_RS15220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC2_RS15225	COG2190	(PTS) system
FORC2_RS15225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC2_RS15225	COG1263	PTS System
FORC2_RS15230	COG0363	glucosamine-6-phosphate deaminase activity
FORC2_RS15235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC2_RS15240	COG1940	carbohydrate kinase activity
FORC2_RS15240	COG1846	Transcriptional regulator
FORC2_RS15245	COG0647	UMP catabolic process
FORC2_RS15250	COG0367	asparagine synthase
FORC2_RS15285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC2_RS15290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC2_RS15295	COG1702	phosphate starvation-inducible protein PhoH
FORC2_RS15300	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC2_RS15305	COG4535	Mg2 and Co2 transporter CorC
FORC2_RS15310	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC2_RS15325	COG0765	amino acid transport
FORC2_RS15330	COG0765	amino acid transport
FORC2_RS15335	COG1126	abc transporter atp-binding protein
FORC2_RS15345	COG2888	peptidyl-tyrosine sulfation
FORC2_RS15350	COG0495	leucyl-tRNA aminoacylation
FORC2_RS15355	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC2_RS15360	COG1466	dna polymerase III delta subunit
FORC2_RS15365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC2_RS15370	COG0799	negative regulation of ribosome biogenesis
FORC2_RS15380	COG0768	penicillin binding
FORC2_RS15385	COG0772	Belongs to the SEDS family
FORC2_RS15390	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC2_RS15395	COG1686	Belongs to the peptidase S11 family
FORC2_RS15400	COG2921	Belongs to the UPF0250 family
FORC2_RS15405	COG0321	lipoyl(octanoyl) transferase activity
FORC2_RS15410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC2_RS15415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC2_RS15420	COG3706	GGDEF domain
FORC2_RS15435	COG1278	Cold shock
FORC2_RS15440	COG2197	response regulator
FORC2_RS15450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC2_RS15465	COG5265	(ABC) transporter
FORC2_RS15475	COG2986	histidine ammonia-lyase
FORC2_RS15480	COG2850	peptidyl-arginine hydroxylation
FORC2_RS15500	COG5002	protein histidine kinase activity
FORC2_RS15520	COG0656	L-ascorbic acid biosynthetic process
FORC2_RS15535	COG1902	pentaerythritol trinitrate reductase activity
FORC2_RS15550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC2_RS15555	COG2501	S4 domain
FORC2_RS15560	COG0215	cysteine-tRNA ligase activity
FORC2_RS15565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC2_RS15570	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC2_RS15575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC2_RS15580	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC2_RS15585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC2_RS15590	COG4181	ATPase activity
FORC2_RS15595	COG2755	lipolytic protein G-D-S-L family
FORC2_RS15600	COG0300	oxidoreductase activity
FORC2_RS15605	COG3118	belongs to the thioredoxin family
FORC2_RS15610	COG0330	HflC and HflK could
FORC2_RS15615	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC2_RS15620	COG0789	Transcriptional regulator
FORC2_RS15625	COG2217	Heavy metal translocating P-type atpase
FORC2_RS15630	COG3735	TraB family
FORC2_RS15635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC2_RS15640	COG0737	Belongs to the 5'-nucleotidase family
FORC2_RS15645	COG2223	nitrite transmembrane transporter activity
FORC2_RS15650	COG4651	solute:proton antiporter activity
FORC2_RS15650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC2_RS15655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC2_RS15680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC2_RS15685	COG0438	transferase activity, transferring glycosyl groups
FORC2_RS15690	COG1216	Glycosyl transferase, family 2
FORC2_RS15690	COG1442	glycosyl transferase family 8
FORC2_RS15695	COG1442	glycosyl transferase family 8
FORC2_RS15695	COG1216	Glycosyl transferase, family 2
FORC2_RS15700	COG2244	polysaccharide biosynthetic process
FORC2_RS15705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC2_RS15710	COG0563	adenylate kinase activity
FORC2_RS15715	COG0326	Molecular chaperone. Has ATPase activity
FORC2_RS15720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC2_RS15725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC2_RS15735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC2_RS15740	COG2832	Protein of unknown function (DUF454)
FORC2_RS15755	COG1196	nuclear chromosome segregation
FORC2_RS15755	COG3264	Mechanosensitive ion channel
FORC2_RS15760	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC2_RS15765	COG1309	transcriptional regulator
FORC2_RS15770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS15775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC2_RS15785	COG3457	Alanine racemase
FORC2_RS15790	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC2_RS15805	COG0254	rRNA binding
FORC2_RS15810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC2_RS15815	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC2_RS15820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC2_RS15850	COG3695	enzyme binding
FORC2_RS15855	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC2_RS15860	COG1946	Acyl-CoA thioesterase
FORC2_RS15865	COG0004	ammonium transporteR
FORC2_RS15870	COG0347	Belongs to the P(II) protein family
FORC2_RS15875	COG1132	(ABC) transporter
FORC2_RS15880	COG1132	(ABC) transporter
FORC2_RS15885	COG1522	sequence-specific DNA binding
FORC2_RS15895	COG0561	phosphatase activity
FORC2_RS15900	COG4533	DNA binding
FORC2_RS15905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC2_RS15910	COG0824	Thioesterase
FORC2_RS15915	COG1555	photosystem II stabilization
FORC2_RS15920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC2_RS15925	COG0776	regulation of translation
FORC2_RS15930	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC2_RS15935	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC2_RS15940	COG0740	serine-type endopeptidase activity
FORC2_RS15945	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC2_RS15950	COG0271	Belongs to the BolA IbaG family
FORC2_RS15955	COG3056	Lipoprotein
FORC2_RS15960	COG2223	nitrite transmembrane transporter activity
FORC2_RS15970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC2_RS15975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC2_RS15980	COG1845	cytochrome c oxidase, subunit III
FORC2_RS15985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FORC2_RS15990	COG0109	protoheme IX farnesyltransferase activity
FORC2_RS15995	COG2814	Major facilitator Superfamily
FORC2_RS16000	COG1666	GTP binding
FORC2_RS16005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC2_RS16015	COG0301	tRNA thio-modification
FORC2_RS16015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC2_RS16020	COG1722	exodeoxyribonuclease VII activity
FORC2_RS16025	COG0142	geranyltranstransferase activity
FORC2_RS16030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC2_RS16035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC2_RS16040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC2_RS16045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC2_RS16050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FORC2_RS16055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC2_RS16055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC2_RS16060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC2_RS16070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC2_RS16075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC2_RS16080	COG1862	Preprotein translocase
FORC2_RS16085	COG0343	queuine tRNA-ribosyltransferase activity
FORC2_RS16095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC2_RS16100	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FORC2_RS16105	COG0450	alkyl hydroperoxide reductase
FORC2_RS16120	COG0366	Alpha amylase catalytic
FORC2_RS16140	COG5002	protein histidine kinase activity
FORC2_RS16145	COG0745	RESPONSE REGULATOR receiver
FORC2_RS16150	COG0420	3'-5' exonuclease activity
FORC2_RS16155	COG0419	ATPase involved in DNA repair
FORC2_RS16160	COG1940	carbohydrate kinase activity
FORC2_RS16165	COG2974	May be involved in recombination
FORC2_RS16170	COG3123	guanosine phosphorylase activity
FORC2_RS16175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC2_RS16200	COG2226	methyltransferase
FORC2_RS16215	COG3459	Glycosyltransferase 36 associated
FORC2_RS16235	COG2188	Transcriptional regulator
FORC2_RS16240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC2_RS16245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC2_RS16255	COG1073	alpha beta
FORC2_RS16260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC2_RS16265	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC2_RS16270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC2_RS16285	COG2964	Protein conserved in bacteria
FORC2_RS16300	COG2991	Protein conserved in bacteria
FORC2_RS16305	COG1477	protein flavinylation
FORC2_RS16310	COG2871	sodium ion transport
FORC2_RS16315	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC2_RS16320	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC2_RS16325	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC2_RS16330	COG1805	sodium ion transport
FORC2_RS16335	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC2_RS16340	COG3034	peptidoglycan biosynthetic process
FORC2_RS16345	COG0121	glutamine amidotransferase
FORC2_RS16350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC2_RS16355	COG1960	acyl-CoA dehydrogenase activity
FORC2_RS16360	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FORC2_RS16375	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FORC2_RS16380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FORC2_RS16385	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FORC2_RS16390	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
FORC2_RS16395	COG0235	Class ii aldolase
FORC2_RS16400	COG0436	Aminotransferase
FORC2_RS16415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC2_RS16425	COG0765	amino acid transport
FORC2_RS16430	COG0765	amino acid transport
FORC2_RS16465	COG2814	Major facilitator Superfamily
FORC2_RS16470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FORC2_RS16480	COG1846	Transcriptional regulator
FORC2_RS16485	COG1538	Outer membrane efflux protein
FORC2_RS16490	COG1566	PFAM secretion protein HlyD family protein
FORC2_RS16495	COG2814	Major facilitator Superfamily
FORC2_RS16500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC2_RS16505	COG3118	belongs to the thioredoxin family
FORC2_RS16510	COG3148	PFAM DTW domain containing protein
FORC2_RS16515	COG1042	CoA-binding domain protein
FORC2_RS16515	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC2_RS16515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC2_RS16520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC2_RS16525	COG5544	Lipoprotein
FORC2_RS16565	COG0542	response to heat
FORC2_RS16570	COG1496	oxidoreductase activity
FORC2_RS16575	COG0564	pseudouridine synthase activity
FORC2_RS16580	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC2_RS16585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC2_RS16590	COG0077	Prephenate dehydratase
FORC2_RS16590	COG1605	Chorismate mutase
FORC2_RS16595	COG0287	Prephenate dehydrogenase
FORC2_RS16595	COG1605	Chorismate mutase
FORC2_RS16600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC2_RS16605	COG3279	Response regulator of the LytR AlgR family
FORC2_RS16610	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC2_RS16615	COG3137	Salt-induced outer membrane protein
FORC2_RS16620	COG0335	large ribosomal subunit rRNA binding
FORC2_RS16625	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC2_RS16630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC2_RS16635	COG0228	four-way junction DNA binding
FORC2_RS16640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC2_RS16645	COG4137	Cytochrome C assembly protein
FORC2_RS16650	COG4536	flavin adenine dinucleotide binding
FORC2_RS16655	COG1854	S-ribosylhomocysteine lyase activity
FORC2_RS16660	COG2918	glutathione biosynthetic process
FORC2_RS16665	COG1238	metal cluster binding
FORC2_RS16670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC2_RS16695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FORC2_RS16700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC2_RS16705	COG2137	regulation of response to DNA damage stimulus
FORC2_RS16710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC2_RS16735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC2_RS16740	COG3958	Transketolase
FORC2_RS16745	COG3959	Transketolase, thiamine diphosphate binding domain
FORC2_RS16750	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS16755	COG1129	ABC transporter
FORC2_RS16765	COG1879	ABC-type sugar transport system periplasmic component
FORC2_RS16780	COG3381	protein complex oligomerization
FORC2_RS16785	COG3302	dmso reductase anchor subunit
FORC2_RS16790	COG0437	4 iron, 4 sulfur cluster binding
FORC2_RS16795	COG0243	molybdopterin cofactor binding
FORC2_RS16800	COG1454	alcohol dehydrogenase
FORC2_RS16805	COG0235	Class ii aldolase
FORC2_RS16810	COG0738	Major facilitator superfamily
FORC2_RS16820	COG1070	Carbohydrate kinase
FORC2_RS16830	COG1349	DNA-binding transcription factor activity
FORC2_RS16840	COG1349	DNA-binding transcription factor activity
FORC2_RS16855	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS16865	COG3623	hexulose-6-phosphate isomerase
FORC2_RS16870	COG1070	Carbohydrate kinase
FORC2_RS16875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC2_RS16875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FORC2_RS16890	COG4177	L-phenylalanine transmembrane transporter activity
FORC2_RS16895	COG1137	ATPase activity
FORC2_RS16900	COG0410	ABC transporter
FORC2_RS16955	COG0640	Transcriptional regulator
FORC2_RS16960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC2_RS16975	COG3665	Urea carboxylase-associated protein
FORC2_RS16980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC2_RS16985	COG1126	abc transporter atp-binding protein
FORC2_RS16990	COG0765	amino acid transport
FORC2_RS16995	COG0765	amino acid transport
FORC2_RS17000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS17005	COG3048	D-serine ammonia-lyase activity
FORC2_RS17010	COG2610	gluconate transmembrane transporter activity
FORC2_RS17015	COG0583	DNA-binding transcription factor activity
FORC2_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
FORC2_RS17045	COG1538	Outer membrane efflux protein
FORC2_RS17055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS17085	COG3539	Fimbrial protein
FORC2_RS17090	COG3539	Fimbrial protein
FORC2_RS17100	COG3121	Chaperone
FORC2_RS17105	COG3188	usher protein
FORC2_RS17130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC2_RS17135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC2_RS17140	COG4942	peptidase
FORC2_RS17140	COG1388	LysM domain
FORC2_RS17145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC2_RS17150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC2_RS17155	COG0585	pseudouridine synthase activity
FORC2_RS17160	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC2_RS17170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC2_RS17180	COG0765	amino acid transport
FORC2_RS17195	COG0529	Catalyzes the synthesis of activated sulfate
FORC2_RS17200	COG2895	sulfate adenylyltransferase (ATP) activity
FORC2_RS17205	COG0175	sulfate reduction
FORC2_RS17210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC2_RS17210	COG1648	precorrin-2 dehydrogenase activity
FORC2_RS17215	COG2234	aminopeptidase activity
FORC2_RS17230	COG0175	sulfate reduction
FORC2_RS17235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC2_RS17240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC2_RS17245	COG0720	synthase
FORC2_RS17250	COG0602	queuosine metabolic process
FORC2_RS17280	COG0148	phosphopyruvate hydratase activity
FORC2_RS17285	COG0504	CTP synthase activity
FORC2_RS17290	COG3956	TIGRFAM MazG family protein
FORC2_RS17295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC2_RS17300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC2_RS17305	COG3850	Histidine kinase
FORC2_RS17305	COG2205	protein histidine kinase activity
FORC2_RS17305	COG3437	response regulator, receiver
FORC2_RS17305	COG4999	Histidine kinase
FORC2_RS17310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC2_RS17315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC2_RS17320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC2_RS17330	COG2860	membrane
FORC2_RS17335	COG0316	Belongs to the HesB IscA family
FORC2_RS17345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC2_RS17350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC2_RS17355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC2_RS17360	COG1120	ATPase activity
FORC2_RS17365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC2_RS17370	COG1643	Atp-dependent helicase
FORC2_RS17375	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FORC2_RS17380	COG1489	DNA binding
FORC2_RS17400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC2_RS17405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC2_RS17410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC2_RS17415	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FORC2_RS17420	COG0726	polysaccharide deacetylase
FORC2_RS17425	COG0842	Transport permease protein
FORC2_RS17430	COG1131	(ABC) transporter
FORC2_RS17435	COG0288	reversible hydration of carbon dioxide
FORC2_RS17440	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC2_RS17450	COG2132	Multicopper oxidase
FORC2_RS17460	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FORC2_RS17465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC2_RS17490	COG0697	spore germination
FORC2_RS17495	COG3112	Uncharacterised protein family (UPF0231)
FORC2_RS17520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC2_RS17525	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC2_RS17530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC2_RS17535	COG2186	Transcriptional regulator
FORC2_RS17540	COG1113	amino acid transport
FORC2_RS17545	COG3725	Membrane protein required for beta-lactamase induction
FORC2_RS17560	COG4969	Belongs to the N-Me-Phe pilin family
FORC2_RS17565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC2_RS17570	COG1459	type II secretion system
FORC2_RS17575	COG0516	GMP reductase activity
FORC2_RS17585	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC2_RS17590	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC2_RS17595	COG0494	nUDIX hydrolase
FORC2_RS17600	COG0653	protein targeting
FORC2_RS17620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC2_RS17625	COG0849	cell division
FORC2_RS17630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC2_RS17640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC2_RS17645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC2_RS17650	COG0772	Belongs to the SEDS family
FORC2_RS17660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC2_RS17665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC2_RS17670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC2_RS17675	COG0768	penicillin binding
FORC2_RS17680	COG3116	cell division
FORC2_RS17685	COG0275	rRNA processing
FORC2_RS17690	COG2001	Belongs to the MraZ family
FORC2_RS17710	COG0028	Belongs to the TPP enzyme family
FORC2_RS17715	COG1022	Amp-dependent synthetase and ligase
FORC2_RS17725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC2_RS17730	COG0473	3-isopropylmalate dehydrogenase activity
FORC2_RS17735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC2_RS17750	COG3033	Beta-eliminating lyase
FORC2_RS17755	COG0814	amino acid
FORC2_RS17760	COG2814	Major facilitator Superfamily
FORC2_RS17770	COG1882	Formate acetyltransferase
FORC2_RS17775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC2_RS17780	COG4533	DNA binding
FORC2_RS17795	COG4143	(ABC) transporter
FORC2_RS17800	COG1178	ABC-type Fe3 transport system permease component
FORC2_RS17810	COG0586	Pfam SNARE associated Golgi protein
FORC2_RS17815	COG0417	DNA replication proofreading
FORC2_RS17820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC2_RS17830	COG0564	pseudouridine synthase activity
FORC2_RS17835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC2_RS17840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC2_RS17850	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC2_RS17855	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC2_RS17860	COG2967	ApaG domain
FORC2_RS17865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC2_RS17870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC2_RS17875	COG3610	response to peptide
FORC2_RS17880	COG2966	Psort location CytoplasmicMembrane, score
FORC2_RS17885	COG1280	lysine exporter protein (LysE YggA)
FORC2_RS17890	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC2_RS17900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC2_RS17905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC2_RS17910	COG1047	Peptidyl-prolyl cis-trans
FORC2_RS17915	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC2_RS17920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC2_RS17925	COG0196	riboflavin kinase activity
FORC2_RS17930	COG0268	Binds directly to 16S ribosomal RNA
FORC2_RS17935	COG0583	DNA-binding transcription factor activity
FORC2_RS17940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC2_RS17945	COG0484	heat shock protein binding
FORC2_RS17955	COG1584	GPR1 FUN34 yaaH family protein
FORC2_RS17965	COG0477	Major facilitator Superfamily
FORC2_RS17970	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC2_RS17975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC2_RS17980	COG3022	response to hydroperoxide
FORC2_RS17990	COG0083	homoserine kinase activity
FORC2_RS18005	COG0745	RESPONSE REGULATOR receiver
FORC2_RS18010	COG3045	CreA protein
FORC2_RS18015	COG3708	Transcriptional regulator
FORC2_RS18015	COG2207	Transcriptional regulator
FORC2_RS18020	COG0406	alpha-ribazole phosphatase activity
FORC2_RS18025	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC2_RS18030	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC2_RS18035	COG0741	lytic transglycosylase activity
FORC2_RS18040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC2_RS18050	COG2199	diguanylate cyclase activity
FORC2_RS18055	COG2885	chlorophyll binding
FORC2_RS18060	COG0488	(ABC) transporter
FORC2_RS18070	COG0604	alcohol dehydrogenase
FORC2_RS18100	COG0560	Phosphoserine phosphatase
FORC2_RS18105	COG3726	membrane protein affecting hemolysin expression
FORC2_RS18110	COG0813	purine-nucleoside phosphorylase activity
FORC2_RS18115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC2_RS18120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC2_RS18130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC2_RS18135	COG0084	hydrolase, TatD family'
FORC2_RS18140	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC2_RS18145	COG2823	Periplasmic or secreted lipoprotein
FORC2_RS18150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FORC2_RS18155	COG0456	acetyltransferase
FORC2_RS18160	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FORC2_RS18165	COG2813	Specifically methylates the guanine in position
FORC2_RS18170	COG0667	Aldo Keto reductase
FORC2_RS18200	COG4772	TonB-dependent receptor
FORC2_RS18235	COG3284	Transcriptional regulator
FORC2_RS18265	COG2192	nodulation
FORC2_RS18275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC2_RS18275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC2_RS18275	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FORC2_RS18280	COG1461	Dihydroxyacetone kinase
FORC2_RS18285	COG2376	Dihydroxyacetone kinase
FORC2_RS18295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC2_RS18300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS18305	COG2235	arginine
FORC2_RS18320	COG0859	PFAM glycosyl transferase family 9
FORC2_RS18325	COG1070	Carbohydrate kinase
FORC2_RS18330	COG2390	Transcriptional regulator
FORC2_RS18335	COG1129	ABC transporter
FORC2_RS18340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS18345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS18350	COG1879	ABC-type sugar transport system periplasmic component
FORC2_RS18355	COG1830	Aldolase
FORC2_RS18360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC2_RS18455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC2_RS18490	COG0582	viral genome integration into host DNA
FORC2_RS18500	COG0795	lipopolysaccharide-transporting ATPase activity
FORC2_RS18505	COG0795	lipopolysaccharide-transporting ATPase activity
FORC2_RS18510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC2_RS18515	COG2927	DNA polymerase III (CHI subunit)
FORC2_RS18530	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FORC2_RS18540	COG2731	YhcH YjgK YiaL family protein
FORC2_RS18550	COG0601	transmembrane transport
FORC2_RS18555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC2_RS18560	COG0444	Belongs to the ABC transporter superfamily
FORC2_RS18565	COG4608	Belongs to the ABC transporter superfamily
FORC2_RS18580	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC2_RS18585	COG0583	DNA-binding transcription factor activity
FORC2_RS18610	COG2188	Transcriptional regulator
FORC2_RS18615	COG3624	Phosphonate C-P lyase system protein PhnG
FORC2_RS18620	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FORC2_RS18625	COG3626	phosphonate metabolism
FORC2_RS18630	COG3627	carbon phosphorus lyase activity
FORC2_RS18635	COG4107	phosphonate C-P lyase system protein PhnK
FORC2_RS18640	COG4778	phosphonate C-P lyase system protein PhnL
FORC2_RS18645	COG3454	Phosphonate metabolism
FORC2_RS18650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FORC2_RS18655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC2_RS18660	COG0702	epimerase
FORC2_RS18670	COG3787	Belongs to the UPF0306 family
FORC2_RS18680	COG3842	ATPase activity
FORC2_RS18685	COG0395	ABC-type sugar transport system, permease component
FORC2_RS18690	COG1175	transmembrane transport
FORC2_RS18695	COG1653	transport
FORC2_RS18710	COG1982	Orn Lys Arg decarboxylase major
FORC2_RS18715	COG0531	amino acid
FORC2_RS18720	COG2827	Endonuclease containing a URI domain
FORC2_RS18725	COG3153	acetyltransferase
FORC2_RS18730	COG3154	lipid carrier protein
FORC2_RS18735	COG0826	peptidase U32
FORC2_RS18740	COG0826	peptidase U32
FORC2_RS18745	COG3681	Belongs to the UPF0597 family
FORC2_RS18750	COG0814	amino acid
FORC2_RS18760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC2_RS18765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC2_RS18770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC2_RS18780	COG0513	Belongs to the DEAD box helicase family
FORC2_RS18790	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC2_RS18795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FORC2_RS18800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC2_RS18805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC2_RS18810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC2_RS18815	COG0195	Participates in both transcription termination and antitermination
FORC2_RS18820	COG0779	Required for maturation of 30S ribosomal subunits
FORC2_RS18835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC2_RS18840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC2_RS18845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC2_RS18855	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC2_RS18860	COG1534	Rna-binding protein
FORC2_RS18870	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC2_RS18875	COG0745	RESPONSE REGULATOR receiver
FORC2_RS18880	COG0642	Histidine kinase
FORC2_RS18885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC2_RS18890	COG0697	spore germination
FORC2_RS18895	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FORC2_RS18900	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC2_RS18905	COG0142	geranyltranstransferase activity
FORC2_RS18915	COG3423	Transcriptional regulator
FORC2_RS18920	COG0039	L-malate dehydrogenase activity
FORC2_RS18925	COG1438	arginine binding
FORC2_RS18935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC2_RS18940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC2_RS18950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC2_RS18955	COG2105	PFAM AIG2 family protein
FORC2_RS18970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC2_RS18975	COG1253	flavin adenine dinucleotide binding
FORC2_RS18985	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC2_RS18990	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC2_RS18995	COG0737	Belongs to the 5'-nucleotidase family
FORC2_RS19005	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC2_RS19010	COG3061	Opacity-associated protein A
FORC2_RS19020	COG0359	binds to the 23S rRNA
FORC2_RS19025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FORC2_RS19030	COG2965	DNA replication, synthesis of RNA primer
FORC2_RS19035	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC2_RS19045	COG1073	alpha beta
FORC2_RS19050	COG3650	response to hydrogen peroxide
FORC2_RS19055	COG1960	acyl-CoA dehydrogenase activity
FORC2_RS19060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC2_RS19065	COG0557	exoribonuclease II activity
FORC2_RS19070	COG1959	2 iron, 2 sulfur cluster binding
FORC2_RS19075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC2_RS19080	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC2_RS19085	COG0330	HflC and HflK could
FORC2_RS19090	COG0330	HflC and HflK could
FORC2_RS19095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC2_RS19100	COG1923	regulation of RNA biosynthetic process
FORC2_RS19105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC2_RS19110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC2_RS19115	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC2_RS19120	COG0802	atpase or kinase
FORC2_RS19125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC2_RS19125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC2_RS19130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC2_RS19150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC2_RS19155	COG1162	GTPase activity
FORC2_RS19160	COG0688	phosphatidylethanolamine metabolic process
FORC2_RS19165	COG1511	domain protein
FORC2_RS19165	COG3264	Mechanosensitive ion channel
FORC2_RS19170	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC2_RS19175	COG1053	succinate dehydrogenase
FORC2_RS19180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC2_RS19185	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC2_RS19190	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC2_RS19210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC2_RS19235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC2_RS19250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC2_RS19260	COG4232	protein-disulfide reductase activity
FORC2_RS19265	COG1929	Belongs to the glycerate kinase type-1 family
FORC2_RS19270	COG1309	transcriptional regulator
FORC2_RS19280	COG1882	Formate acetyltransferase
FORC2_RS19285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC2_RS19290	COG0814	amino acid
FORC2_RS19305	COG3721	Heme iron utilization protein
FORC2_RS19310	COG0702	epimerase
FORC2_RS19325	COG3720	iron ion transport
FORC2_RS19330	COG4558	Periplasmic binding protein
FORC2_RS19335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC2_RS19340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC2_RS19345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC2_RS19355	COG4774	siderophore transport
FORC2_RS19360	COG1511	domain protein
FORC2_RS19360	COG3264	Mechanosensitive ion channel
FORC2_RS19365	COG0612	Peptidase, M16
FORC2_RS19370	COG4178	(ABC) transporter
FORC2_RS19375	COG4771	TonB-dependent receptor
FORC2_RS19380	COG3712	iron ion homeostasis
FORC2_RS19395	COG0425	Belongs to the sulfur carrier protein TusA family
FORC2_RS19400	COG2391	methyltransferase activity
FORC2_RS19555	COG0784	Response regulator, receiver
FORC2_RS19555	COG2205	protein histidine kinase activity
FORC2_RS19560	COG2197	response regulator
FORC2_RS19565	COG1301	dicarboxylic acid transport
FORC2_RS19570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC2_RS19575	COG3162	membrane
FORC2_RS19580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC2_RS19630	COG0138	bifunctional purine biosynthesis protein purh
FORC2_RS19635	COG0151	Belongs to the GarS family
FORC2_RS19655	COG1515	deoxyribonuclease V activity
FORC2_RS19660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC2_RS19670	COG2816	NAD+ diphosphatase activity
FORC2_RS19675	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC2_RS19690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC2_RS19695	COG2104	thiamine diphosphate biosynthetic process
FORC2_RS19700	COG2022	thiamine diphosphate biosynthetic process
FORC2_RS19710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC2_RS19715	COG0085	RNA polymerase activity
FORC2_RS19720	COG0222	ribosome binding
FORC2_RS19725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC2_RS19730	COG0081	regulation of translation
FORC2_RS19735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC2_RS19740	COG0250	Participates in transcription elongation, termination and antitermination
FORC2_RS19750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC2_RS19780	COG1072	(Pantothenic acid kinase))
FORC2_RS19785	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FORC2_RS19785	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FORC2_RS19820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC2_RS19825	COG1739	Uncharacterized protein family UPF0029
FORC2_RS19830	COG0006	proline dipeptidase activity
FORC2_RS19835	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC2_RS19835	COG1024	Enoyl-CoA hydratase
FORC2_RS19840	COG0183	Belongs to the thiolase family
FORC2_RS19850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC2_RS19870	COG0805	protein transport
FORC2_RS19875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC2_RS19880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC2_RS19885	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC2_RS19895	COG2226	methyltransferase
FORC2_RS19900	COG1322	Protein conserved in bacteria
FORC2_RS19905	COG0586	Pfam SNARE associated Golgi protein
FORC2_RS19910	COG1966	Carbon starvation protein
FORC2_RS19925	COG0412	Dienelactone hydrolase
FORC2_RS19930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC2_RS19935	COG0583	DNA-binding transcription factor activity
FORC2_RS19940	COG0697	spore germination
FORC2_RS19945	COG0679	Auxin Efflux Carrier
FORC2_RS19950	COG0584	glycerophosphoryl diester phosphodiesterase
FORC2_RS19955	COG3842	ATPase activity
FORC2_RS19960	COG0395	ABC-type sugar transport system, permease component
FORC2_RS19965	COG1175	transmembrane transport
FORC2_RS19970	COG1653	transport
FORC2_RS20005	COG0410	ABC transporter
FORC2_RS20015	COG4177	L-phenylalanine transmembrane transporter activity
FORC2_RS20025	COG0683	leucine binding
FORC2_RS20040	COG2177	Part of the ABC transporter FtsEX involved in
FORC2_RS20045	COG2884	Cell division ATP-binding protein ftsE
FORC2_RS20050	COG0552	protein localization to endoplasmic reticulum
FORC2_RS20055	COG0742	ribosomal rna small subunit methyltransferase
FORC2_RS20060	COG3776	membrane
FORC2_RS20075	COG3714	YhhN family
FORC2_RS20080	COG2217	Heavy metal translocating P-type atpase
FORC2_RS20085	COG0425	Belongs to the sulfur carrier protein TusA family
FORC2_RS20090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC2_RS20100	COG0247	lactate metabolic process
FORC2_RS20105	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FORC2_RS20110	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC2_RS20115	COG2271	Major facilitator Superfamily
FORC2_RS20120	COG0584	glycerophosphoryl diester phosphodiesterase
FORC2_RS20125	COG0561	phosphatase activity
FORC2_RS20130	COG2267	carboxylic ester hydrolase activity
FORC2_RS20135	COG1280	lysine exporter protein (LysE YggA)
FORC2_RS20140	COG1280	lysine exporter protein (LysE YggA)
FORC2_RS20145	COG0514	ATP-dependent DNA helicase (RecQ)
FORC2_RS20150	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FORC2_RS20155	COG2050	protein possibly involved in aromatic compounds catabolism
FORC2_RS20170	COG5564	TIM-barrel signal transduction protein
FORC2_RS20175	COG5441	Belongs to the UPF0261 family
FORC2_RS20185	COG0210	DNA helicase
FORC2_RS20190	COG1011	Hydrolase
FORC2_RS20195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC2_RS20200	COG3159	Protein conserved in bacteria
FORC2_RS20205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC2_RS20215	COG1965	Belongs to the frataxin family
FORC2_RS20220	COG3072	Adenylate cyclase
FORC2_RS20225	COG0181	hydroxymethylbilane synthase activity
FORC2_RS20230	COG1587	Uroporphyrinogen-III synthase
FORC2_RS20235	COG2959	enzyme of heme biosynthesis
FORC2_RS20240	COG3071	HemY protein
FORC2_RS20280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC2_RS20285	COG2244	polysaccharide biosynthetic process
FORC2_RS20290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC2_RS20295	COG0456	acetyltransferase
FORC2_RS20300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC2_RS20305	COG1088	dTDP-glucose 4,6-dehydratase activity
FORC2_RS20310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC2_RS20315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC2_RS20320	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FORC2_RS20325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC2_RS20330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC2_RS20335	COG3118	belongs to the thioredoxin family
FORC2_RS20345	COG0248	Ppx GppA phosphatase
FORC2_RS20360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC2_RS20370	COG3121	Chaperone
FORC2_RS20385	COG3121	Chaperone
FORC2_RS20410	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC2_RS20415	COG0583	DNA-binding transcription factor activity
FORC2_RS20425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC2_RS20430	COG0129	dihydroxy-acid dehydratase activity
FORC2_RS20435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC2_RS20440	COG3978	acetolactate synthase activity
FORC2_RS20455	COG3085	chromosome segregation
FORC2_RS20460	COG0583	DNA-binding transcription factor activity
FORC2_RS20465	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS20470	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS20475	COG1129	ABC transporter
FORC2_RS20480	COG1879	ABC-type sugar transport system periplasmic component
FORC2_RS20520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC2_RS20530	COG3148	PFAM DTW domain containing protein
FORC2_RS20540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC2_RS20545	COG5544	Lipoprotein
FORC2_RS20575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC2_RS20585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC2_RS20595	COG1309	transcriptional regulator
FORC2_RS20600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC2_RS20610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC2_RS20610	COG0678	peroxiredoxin activity
FORC2_RS20615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC2_RS20655	COG1629	transport
FORC2_RS20660	COG0165	Argininosuccinate lyase
FORC2_RS20665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC2_RS20680	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC2_RS20690	COG0527	aspartate kinase activity
FORC2_RS20690	COG0460	homoserine dehydrogenase
FORC2_RS20695	COG0626	cystathionine gamma-synthase activity
FORC2_RS20700	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FORC2_RS20705	COG0254	rRNA binding
FORC2_RS20710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC2_RS20715	COG1609	Transcriptional regulator
FORC2_RS20720	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC2_RS20725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC2_RS20730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC2_RS20735	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC2_RS20740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC2_RS20745	COG3074	FtsZ-dependent cytokinesis
FORC2_RS20755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC2_RS20760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC2_RS20765	COG1494	fructose-1,6-bisphosphatase
FORC2_RS20770	COG2814	Major facilitator Superfamily
FORC2_RS20780	COG3152	Membrane
FORC2_RS20790	COG0149	triose-phosphate isomerase activity
FORC2_RS20800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC2_RS20810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC2_RS20815	COG3678	ATP-independent chaperone mediated protein folding
FORC2_RS20820	COG0745	RESPONSE REGULATOR receiver
FORC2_RS20825	COG2205	protein histidine kinase activity
FORC2_RS20830	COG2169	Transcriptional regulator
FORC2_RS20830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC2_RS20835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC2_RS20840	COG1045	serine acetyltransferase
FORC2_RS20845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC2_RS20850	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC2_RS20855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC2_RS20860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC2_RS20865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC2_RS20870	COG4942	peptidase
FORC2_RS20875	COG2861	carbohydrate metabolic process
FORC2_RS20880	COG1063	alcohol dehydrogenase
FORC2_RS20885	COG0156	8-amino-7-oxononanoate synthase activity
FORC2_RS20890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC2_RS20895	COG0859	PFAM glycosyl transferase family 9
FORC2_RS20900	COG0859	PFAM glycosyl transferase family 9
FORC2_RS20905	COG1519	Transferase
FORC2_RS20915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FORC2_RS20920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC2_RS20925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC2_RS20930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC2_RS20935	COG2003	Belongs to the UPF0758 family
FORC2_RS20940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC2_RS20945	COG0756	dUTP diphosphatase activity
FORC2_RS20950	COG1309	transcriptional regulator
FORC2_RS20955	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC2_RS20960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC2_RS20965	COG1561	YicC-like family, N-terminal region
FORC2_RS20975	COG5001	Diguanylate cyclase
FORC2_RS20980	COG1024	Enoyl-CoA hydratase
FORC2_RS20985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC2_RS20995	COG2860	membrane
FORC2_RS21000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC2_RS21010	COG1758	RNA polymerase activity
FORC2_RS21015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC2_RS21020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC2_RS21025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC2_RS21030	COG0786	glutamate:sodium symporter activity
FORC2_RS21035	COG2233	PERMEase
FORC2_RS21040	COG2982	Protein involved in outer membrane biogenesis
FORC2_RS21060	COG3423	Transcriptional regulator
FORC2_RS21065	COG0456	acetyltransferase
FORC2_RS21070	COG1490	D-aminoacyl-tRNA deacylase activity
FORC2_RS21075	COG1295	ribonuclease BN
FORC2_RS21080	COG1011	Hydrolase
FORC2_RS21095	COG3852	Histidine kinase
FORC2_RS21105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC2_RS21110	COG3078	GTPase activator activity
FORC2_RS21115	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC2_RS21120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC2_RS21120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC2_RS21125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC2_RS21130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC2_RS21135	COG3084	Protein conserved in bacteria
FORC2_RS21145	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC2_RS21170	COG2186	Transcriptional regulator
FORC2_RS21175	COG0477	Major facilitator Superfamily
FORC2_RS21180	COG1609	Transcriptional regulator
FORC2_RS21185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC2_RS21190	COG1879	ABC-type sugar transport system periplasmic component
FORC2_RS21195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC2_RS21205	COG1869	D-ribose catabolic process
FORC2_RS21210	COG3158	transport of potassium into the cell
FORC2_RS21215	COG0714	Associated with various cellular activities
FORC2_RS21220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC2_RS21230	COG2502	aspartate--ammonia ligase
FORC2_RS21235	COG1522	sequence-specific DNA binding
FORC2_RS21240	COG0716	FMN binding
FORC2_RS21245	COG0445	tRNA wobble uridine modification
FORC2_RS21250	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC2_RS21255	COG3312	ion transport
FORC2_RS21260	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC2_RS21270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FORC2_RS21275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC2_RS21280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC2_RS21285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC2_RS21290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC2_RS21295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC2_RS21300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC2_RS21310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC2_RS21315	COG0573	inorganic phosphate transmembrane transporter activity
FORC2_RS21320	COG0581	inorganic phosphate transmembrane transporter activity
FORC2_RS21330	COG0704	Plays a role in the regulation of phosphate uptake
FORC2_RS21340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC2_RS21345	COG0765	amino acid transport
FORC2_RS21350	COG0765	amino acid transport
FORC2_RS21355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC2_RS21360	COG2252	PERMEase
FORC2_RS21370	COG4566	intracellular signal transduction
FORC2_RS21375	COG4191	Histidine kinase
FORC2_RS21380	COG0431	NADPH-dependent FMN reductase
FORC2_RS21385	COG0840	transmembrane signaling receptor activity
FORC2_RS21390	COG2011	ABC-type metal ion transport system permease component
FORC2_RS21405	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC2_RS21410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC2_RS21415	COG0706	membrane insertase activity
FORC2_RS21425	COG0594	ribonuclease P activity
FORC2_RS21430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC2_RS21460	COG0187	DNA topoisomerase II activity
FORC2_RS21530	COG0366	Alpha amylase catalytic
FORC2_RS21545	COG0477	Major facilitator Superfamily
FORC2_RS21695	COG3383	formate dehydrogenase (NAD+) activity
FORC2_RS21695	COG0243	molybdopterin cofactor binding
FORC2_RS21700	COG0437	4 iron, 4 sulfur cluster binding
FORC2_RS21730	COG3274	enterobacterial common antigen metabolic process
FORC2_RS21910	COG3188	usher protein
FORC2_RS21930	COG2986	histidine ammonia-lyase
FORC2_RS21980	COG3210	domain, Protein
FORC2_RS21985	COG2755	lipolytic protein G-D-S-L family
FORC2_RS21985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FORC2_RS21990	COG2197	response regulator
FORC2_RS21995	COG3210	domain, Protein