locus-tag	class	description
XM56_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XM56_RS00010	COG0592	DNA-directed DNA polymerase activity
XM56_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XM56_RS00020	COG0187	DNA topoisomerase II activity
XM56_RS00025	COG0561	phosphatase activity
XM56_RS00030	COG2423	ornithine cyclodeaminase activity
XM56_RS00040	COG0823	Involved in the tonB-independent uptake of proteins
XM56_RS00045	COG5645	(Lipo)protein
XM56_RS00060	COG2985	domain, Protein
XM56_RS00060	COG0569	domain protein
XM56_RS00065	COG3977	Valine--pyruvate aminotransferase
XM56_RS00070	COG0366	Alpha amylase catalytic
XM56_RS00075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XM56_RS00105	COG0456	acetyltransferase
XM56_RS00110	COG2818	Glycosylase
XM56_RS00115	COG0752	glycyl-tRNA synthetase alpha subunit
XM56_RS00120	COG0751	glycine-tRNA ligase activity
XM56_RS00130	COG2213	PTS system mannitol-specific
XM56_RS00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS00135	COG0246	Mannitol dehydrogenase
XM56_RS00140	COG3722	fumarate hydratase activity
XM56_RS00150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XM56_RS00170	COG2258	MOSC domain
XM56_RS00175	COG0840	transmembrane signaling receptor activity
XM56_RS00180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XM56_RS00185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
XM56_RS00190	COG3383	formate dehydrogenase (NAD+) activity
XM56_RS00190	COG0243	molybdopterin cofactor binding
XM56_RS00195	COG0243	molybdopterin cofactor binding
XM56_RS00195	COG3383	formate dehydrogenase (NAD+) activity
XM56_RS00200	COG0437	4 iron, 4 sulfur cluster binding
XM56_RS00205	COG2864	formate dehydrogenase
XM56_RS00210	COG3058	Necessary for formate dehydrogenase activity
XM56_RS00215	COG1921	L-seryl-tRNASec selenium transferase activity
XM56_RS00220	COG3276	selenocysteine insertion sequence binding
XM56_RS00230	COG3274	enterobacterial common antigen metabolic process
XM56_RS00245	COG3121	Chaperone
XM56_RS00250	COG1070	Carbohydrate kinase
XM56_RS00255	COG2115	Belongs to the xylose isomerase family
XM56_RS00260	COG4213	ABC transporter substrate-binding protein
XM56_RS00270	COG4214	carbohydrate transport
XM56_RS00275	COG1609	Transcriptional regulator
XM56_RS00275	COG2207	Transcriptional regulator
XM56_RS00280	COG0582	viral genome integration into host DNA
XM56_RS00315	COG2986	histidine ammonia-lyase
XM56_RS00320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
XM56_RS00335	COG1482	cell wall glycoprotein biosynthetic process
XM56_RS00340	COG2723	6-phospho-beta-galactosidase activity
XM56_RS00355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XM56_RS00360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XM56_RS00365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XM56_RS00370	COG1447	Phosphotransferase system cellobiose-specific component IIA
XM56_RS00375	COG1940	carbohydrate kinase activity
XM56_RS00380	COG1609	Transcriptional regulator
XM56_RS00405	COG3328	transposase activity
XM56_RS00415	COG3210	domain, Protein
XM56_RS00420	COG2831	hemolysin activation secretion protein
XM56_RS00440	COG2271	Major facilitator Superfamily
XM56_RS00445	COG3851	Histidine kinase
XM56_RS00450	COG2197	response regulator
XM56_RS00455	COG2194	sulfuric ester hydrolase activity
XM56_RS00460	COG1764	response to oxidative stress
XM56_RS00470	COG0747	negative chemotaxis
XM56_RS00475	COG0601	transmembrane transport
XM56_RS00480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XM56_RS00485	COG0444	Belongs to the ABC transporter superfamily
XM56_RS00490	COG4608	Belongs to the ABC transporter superfamily
XM56_RS00495	COG2194	sulfuric ester hydrolase activity
XM56_RS00515	COG1192	Involved in chromosome partitioning
XM56_RS00520	COG1215	transferase activity, transferring glycosyl groups
XM56_RS00525	COG1215	transferase activity, transferring glycosyl groups
XM56_RS00530	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
XM56_RS00545	COG2200	EAL domain
XM56_RS00545	COG2199	diguanylate cyclase activity
XM56_RS00550	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XM56_RS00565	COG1301	dicarboxylic acid transport
XM56_RS00570	COG0612	Peptidase, M16
XM56_RS00575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XM56_RS00580	COG1942	4-Oxalocrotonate Tautomerase
XM56_RS00585	COG2200	EAL domain
XM56_RS00590	COG2982	Protein involved in outer membrane biogenesis
XM56_RS00595	COG2134	cdp-diacylglycerol pyrophosphatase
XM56_RS00600	COG1295	ribonuclease BN
XM56_RS00610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XM56_RS00615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
XM56_RS00625	COG0742	ribosomal rna small subunit methyltransferase
XM56_RS00640	COG0589	response to stress
XM56_RS00650	COG0306	phosphate transporter
XM56_RS00655	COG2081	HI0933 family
XM56_RS00660	COG1301	dicarboxylic acid transport
XM56_RS00675	COG3799	methylaspartate ammonia-lyase activity
XM56_RS00680	COG4865	methylaspartate mutase activity
XM56_RS00690	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XM56_RS00700	COG1648	precorrin-2 dehydrogenase activity
XM56_RS00700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XM56_RS00705	COG0583	DNA-binding transcription factor activity
XM56_RS00710	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XM56_RS00710	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XM56_RS00720	COG0561	phosphatase activity
XM56_RS00730	COG0583	DNA-binding transcription factor activity
XM56_RS00735	COG2814	Major facilitator Superfamily
XM56_RS00745	COG3718	enzyme involved in inositol metabolism
XM56_RS00755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XM56_RS00765	COG0673	inositol 2-dehydrogenase activity
XM56_RS00770	COG1082	Xylose isomerase domain protein TIM barrel
XM56_RS00775	COG1247	-acetyltransferase
XM56_RS00780	COG1741	Belongs to the pirin family
XM56_RS00785	COG1609	Transcriptional regulator
XM56_RS00790	COG2610	gluconate transmembrane transporter activity
XM56_RS00795	COG3265	gluconokinase activity
XM56_RS00800	COG2095	MarC family integral membrane protein
XM56_RS00805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XM56_RS00825	COG3275	phosphorelay sensor kinase activity
XM56_RS00830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
XM56_RS00835	COG1523	belongs to the glycosyl hydrolase 13 family
XM56_RS00845	COG0297	glycogen (starch) synthase activity
XM56_RS00850	COG0058	SHG alpha-glucan phosphorylase activity
XM56_RS00855	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XM56_RS00865	COG1349	DNA-binding transcription factor activity
XM56_RS00870	COG0705	Rhomboid family
XM56_RS00885	COG2909	trisaccharide binding
XM56_RS00890	COG0058	SHG alpha-glucan phosphorylase activity
XM56_RS00895	COG1640	4-alpha-glucanotransferase
XM56_RS00905	COG0316	Belongs to the HesB IscA family
XM56_RS00905	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
XM56_RS00915	COG0596	Alpha beta hydrolase
XM56_RS00930	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
XM56_RS00935	COG1918	ferrous iron import across plasma membrane
XM56_RS00940	COG2183	response to ionizing radiation
XM56_RS00965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XM56_RS00985	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
XM56_RS00995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
XM56_RS01000	COG1011	Hydrolase
XM56_RS01010	COG0494	nUDIX hydrolase
XM56_RS01015	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
XM56_RS01040	COG4796	Type ii and iii secretion system protein
XM56_RS01045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XM56_RS01065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
XM56_RS01075	COG0180	Tryptophanyl-tRNA synthetase
XM56_RS01080	COG1648	precorrin-2 dehydrogenase activity
XM56_RS01080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XM56_RS01095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XM56_RS01100	COG0402	S-adenosylhomocysteine deaminase activity
XM56_RS01105	COG0738	Major facilitator superfamily
XM56_RS01115	COG1486	melibiose metabolic process
XM56_RS01120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XM56_RS01125	COG0433	COG0433 Predicted ATPase
XM56_RS01140	COG1289	transmembrane transporter activity
XM56_RS01150	COG1765	OsmC-like protein
XM56_RS01155	COG3954	Phosphoribulokinase
XM56_RS01160	COG3089	Belongs to the UPF0270 family
XM56_RS01165	COG0429	hydrolase of the alpha beta-hydrolase fold
XM56_RS01180	COG4521	taurine ABC transporter
XM56_RS01190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
XM56_RS01195	COG2175	clavaminate synthase activity
XM56_RS01205	COG1216	Glycosyl transferase, family 2
XM56_RS01210	COG0488	(ABC) transporter
XM56_RS01215	COG2249	NAD(P)H dehydrogenase (quinone) activity
XM56_RS01225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
XM56_RS01230	COG1047	Peptidyl-prolyl cis-trans
XM56_RS01235	COG2900	Belongs to the SlyX family
XM56_RS01240	COG0545	Peptidyl-prolyl cis-trans isomerase
XM56_RS01245	COG2964	Protein conserved in bacteria
XM56_RS01250	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
XM56_RS01255	COG2923	Belongs to the DsrF TusC family
XM56_RS01260	COG2168	tRNA wobble position uridine thiolation
XM56_RS01265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
XM56_RS01270	COG0049	tRNA binding
XM56_RS01280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XM56_RS01295	COG0051	transcription antitermination factor activity, RNA binding
XM56_RS01300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
XM56_RS01305	COG0088	Forms part of the polypeptide exit tunnel
XM56_RS01310	COG0089	rRNA binding
XM56_RS01315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
XM56_RS01320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
XM56_RS01325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
XM56_RS01330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
XM56_RS01335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
XM56_RS01340	COG0255	Belongs to the universal ribosomal protein uL29 family
XM56_RS01345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
XM56_RS01350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
XM56_RS01355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
XM56_RS01360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
XM56_RS01365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
XM56_RS01375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
XM56_RS01380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
XM56_RS01385	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
XM56_RS01390	COG1841	ribosomal large subunit assembly
XM56_RS01395	COG0200	Binds to the 23S rRNA
XM56_RS01400	COG0201	protein transport
XM56_RS01405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XM56_RS01410	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
XM56_RS01415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
XM56_RS01420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
XM56_RS01425	COG0202	RNA polymerase activity
XM56_RS01430	COG0203	ribosomal protein L17
XM56_RS01440	COG0789	Transcriptional regulator
XM56_RS01445	COG3036	rescue of stalled ribosome
XM56_RS01455	COG1970	mechanosensitive ion channel activity
XM56_RS01465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
XM56_RS01465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XM56_RS01470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XM56_RS01475	COG0242	peptide deformylase activity
XM56_RS01480	COG0758	DNA mediated transformation
XM56_RS01490	COG0551	DNA topoisomerase type I activity
XM56_RS01495	COG0009	L-threonylcarbamoyladenylate synthase
XM56_RS01500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XM56_RS01505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
XM56_RS01545	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
XM56_RS01550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
XM56_RS01555	COG2224	Isocitrate lyase
XM56_RS01560	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
XM56_RS01565	COG1414	Transcriptional regulator
XM56_RS01590	COG0527	aspartate kinase activity
XM56_RS01595	COG0166	Belongs to the GPI family
XM56_RS01605	COG3833	ABC-type maltose transport systems, permease component
XM56_RS01610	COG1175	transmembrane transport
XM56_RS01615	COG2182	Extracellular solute-binding protein
XM56_RS01625	COG4580	involved in the transport of maltose and maltodextrins
XM56_RS01640	COG3161	chorismate lyase activity
XM56_RS01645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
XM56_RS01650	COG2937	Belongs to the GPAT DAPAT family
XM56_RS01655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
XM56_RS01660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
XM56_RS01665	COG3237	CsbD-like
XM56_RS01670	COG0735	belongs to the Fur family
XM56_RS01680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XM56_RS01710	COG1448	Aminotransferase
XM56_RS01720	COG2315	Protein conserved in bacteria
XM56_RS01725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
XM56_RS01775	COG3550	peptidyl-serine autophosphorylation
XM56_RS01790	COG2252	PERMEase
XM56_RS01795	COG0025	NhaP-type Na H and K H
XM56_RS01800	COG0583	DNA-binding transcription factor activity
XM56_RS01805	COG1380	Effector of murein hydrolase LrgA
XM56_RS01815	COG1126	abc transporter atp-binding protein
XM56_RS01820	COG0765	amino acid transport
XM56_RS01825	COG4597	amino acid ABC transporter
XM56_RS01830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS01840	COG1560	Kdo2-lipid A biosynthetic process
XM56_RS01845	COG0471	metal ion transport
XM56_RS01850	COG1278	Cold shock
XM56_RS01855	COG1278	Cold shock
XM56_RS01860	COG3133	Outer membrane lipoprotein
XM56_RS01870	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
XM56_RS01875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XM56_RS01880	COG2264	protein methyltransferase activity
XM56_RS01885	COG4145	pantothenate transmembrane transporter activity
XM56_RS01890	COG3924	membrane
XM56_RS01895	COG0439	Biotin carboxylase
XM56_RS01900	COG0511	ligase activity, forming carbon-carbon bonds
XM56_RS01905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
XM56_RS01910	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
XM56_RS01920	COG0604	alcohol dehydrogenase
XM56_RS01925	COG2199	diguanylate cyclase activity
XM56_RS01925	COG2200	EAL domain
XM56_RS01930	COG1077	Cell shape determining protein MreB Mrl
XM56_RS01935	COG1792	Involved in formation and maintenance of cell shape
XM56_RS01940	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
XM56_RS01945	COG0424	maF-like protein
XM56_RS01955	COG3164	Protein of unknown function
XM56_RS01960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XM56_RS01965	COG0312	modulator of DNA gyrase
XM56_RS02030	COG0583	DNA-binding transcription factor activity
XM56_RS02040	COG1566	PFAM secretion protein HlyD family protein
XM56_RS02045	COG1289	transmembrane transporter activity
XM56_RS02060	COG2732	(Barnase) inhibitor
XM56_RS02065	COG3028	Belongs to the UPF0307 family
XM56_RS02070	COG0312	modulator of DNA gyrase
XM56_RS02080	COG3783	Cytochrome b(562)
XM56_RS02085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
XM56_RS02115	COG3964	amidohydrolase
XM56_RS02130	COG2706	6-phosphogluconolactonase activity
XM56_RS02135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS02135	COG3711	transcriptional antiterminator
XM56_RS02140	COG3093	addiction module antidote protein HigA
XM56_RS02150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XM56_RS02160	COG1263	PTS System
XM56_RS02160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS02165	COG0366	Alpha amylase catalytic
XM56_RS02185	COG2308	Evidence 4 Homologs of previously reported genes of
XM56_RS02195	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
XM56_RS02200	COG0540	Belongs to the ATCase OTCase family
XM56_RS02205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS02210	COG1660	Displays ATPase and GTPase activities
XM56_RS02225	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
XM56_RS02230	COG1137	ATPase activity
XM56_RS02235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
XM56_RS02240	COG3117	lipopolysaccharide transmembrane transporter activity
XM56_RS02245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
XM56_RS02250	COG0517	IMP dehydrogenase activity
XM56_RS02250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
XM56_RS02255	COG0530	calcium, potassium:sodium antiporter activity
XM56_RS02260	COG1127	ABC transporter
XM56_RS02265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XM56_RS02270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XM56_RS02275	COG2854	intermembrane phospholipid transfer
XM56_RS02280	COG3113	response to antibiotic
XM56_RS02285	COG5007	Belongs to the BolA IbaG family
XM56_RS02290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
XM56_RS02295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XM56_RS02300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XM56_RS02305	COG3105	Protein conserved in bacteria
XM56_RS02310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
XM56_RS02315	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
XM56_RS02320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
XM56_RS02325	COG0625	glutathione transferase activity
XM56_RS02330	COG2969	positive regulation of protein catabolic process
XM56_RS02345	COG0493	'glutamate synthase
XM56_RS02350	COG0067	glutamate synthase
XM56_RS02350	COG0069	glutamate synthase activity
XM56_RS02350	COG0070	glutamate synthase
XM56_RS02355	COG1242	4 iron, 4 sulfur cluster binding
XM56_RS02360	COG0784	Response regulator, receiver
XM56_RS02360	COG2198	Histidine kinase
XM56_RS02360	COG5002	protein histidine kinase activity
XM56_RS02365	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
XM56_RS02370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XM56_RS02375	COG2823	Periplasmic or secreted lipoprotein
XM56_RS02380	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
XM56_RS02385	COG0792	nuclease activity
XM56_RS02395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
XM56_RS02410	COG3121	Chaperone
XM56_RS02430	COG0667	Aldo Keto reductase
XM56_RS02435	COG1064	alcohol dehydrogenase
XM56_RS02440	COG1741	Belongs to the pirin family
XM56_RS02445	COG0583	DNA-binding transcription factor activity
XM56_RS02450	COG0435	Glutathione S-transferase
XM56_RS02455	COG2259	Doxx family
XM56_RS02465	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
XM56_RS02470	COG4575	ribosome binding
XM56_RS02485	COG0586	Pfam SNARE associated Golgi protein
XM56_RS02500	COG2271	Major facilitator Superfamily
XM56_RS02505	COG1904	glucuronate isomerase
XM56_RS02510	COG0246	Mannitol dehydrogenase
XM56_RS02515	COG2721	sulfolactate sulfo-lyase activity
XM56_RS02525	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
XM56_RS02530	COG0861	Integral membrane protein TerC family
XM56_RS02540	COG0673	inositol 2-dehydrogenase activity
XM56_RS02545	COG1451	nucleotide metabolic process
XM56_RS02565	COG2813	Specifically methylates the guanine in position
XM56_RS02575	COG1902	pentaerythritol trinitrate reductase activity
XM56_RS02575	COG0446	pyridine nucleotide-disulphide oxidoreductase
XM56_RS02585	COG3247	response to pH
XM56_RS02595	COG0076	glutamate decarboxylase activity
XM56_RS02600	COG0531	amino acid
XM56_RS02610	COG1263	PTS System
XM56_RS02610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS02615	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
XM56_RS02625	COG1472	Belongs to the glycosyl hydrolase 3 family
XM56_RS02635	COG3876	Protein conserved in bacteria
XM56_RS02655	COG0358	DNA primase activity
XM56_RS02660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
XM56_RS02665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
XM56_RS02670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
XM56_RS02675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
XM56_RS02680	COG1968	undecaprenyl-diphosphatase activity
XM56_RS02685	COG0617	tRNA 3'-terminal CCA addition
XM56_RS02690	COG4991	sh3 domain protein
XM56_RS02695	COG3025	triphosphatase activity
XM56_RS02700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
XM56_RS02705	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
XM56_RS02705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
XM56_RS02710	COG0531	amino acid
XM56_RS02720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
XM56_RS02725	COG3384	dioxygenase
XM56_RS02730	COG0754	glutathionylspermidine amidase activity
XM56_RS02735	COG5463	Belongs to the UPF0441 family
XM56_RS02740	COG1538	Outer membrane efflux protein
XM56_RS02745	COG0494	nUDIX hydrolase
XM56_RS02750	COG3151	Protein conserved in bacteria
XM56_RS02755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
XM56_RS02760	COG3150	esterase
XM56_RS02775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
XM56_RS02780	COG2249	NAD(P)H dehydrogenase (quinone) activity
XM56_RS02785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
XM56_RS02795	COG2132	Multicopper oxidase
XM56_RS02805	COG0656	L-ascorbic acid biosynthetic process
XM56_RS02810	COG1979	alcohol dehydrogenase
XM56_RS02815	COG2207	Transcriptional regulator
XM56_RS02820	COG0586	Pfam SNARE associated Golgi protein
XM56_RS02825	COG0626	cystathionine gamma-synthase activity
XM56_RS02835	COG0848	biopolymer transport protein
XM56_RS02885	COG4964	Belongs to the GSP D family
XM56_RS02915	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XM56_RS02920	COG2135	peptidase activity
XM56_RS02955	COG0577	efflux transmembrane transporter activity
XM56_RS02955	COG1136	(ABC) transporter
XM56_RS02970	COG2801	Transposase and inactivated derivatives
XM56_RS02985	COG1120	ATPase activity
XM56_RS02990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XM56_RS02995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XM56_RS03000	COG4592	Periplasmic binding protein
XM56_RS03005	COG2271	Major facilitator Superfamily
XM56_RS03010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XM56_RS03015	COG0840	transmembrane signaling receptor activity
XM56_RS03030	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XM56_RS03040	COG1987	bacterial-type flagellum assembly
XM56_RS03065	COG1677	Flagellar hook-basal body complex protein FliE
XM56_RS03115	COG1815	bacterial-type flagellum-dependent cell motility
XM56_RS03120	COG1558	bacterial-type flagellum-dependent cell motility
XM56_RS03125	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XM56_RS03140	COG4786	Flagellar basal body rod
XM56_RS03150	COG1706	bacterial-type flagellum-dependent cell motility
XM56_RS03180	COG3710	Transcriptional regulator
XM56_RS03185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
XM56_RS03190	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
XM56_RS03195	COG1516	flagellar protein fliS
XM56_RS03215	COG1191	sigma factor activity
XM56_RS03220	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
XM56_RS03230	COG3133	Outer membrane lipoprotein
XM56_RS03235	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
XM56_RS03240	COG0437	4 iron, 4 sulfur cluster binding
XM56_RS03245	COG5557	Pfam Polysulphide reductase, NrfD
XM56_RS03250	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
XM56_RS03255	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
XM56_RS03260	COG1773	rubredoxin
XM56_RS03270	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XM56_RS03275	COG0298	carbon dioxide binding
XM56_RS03280	COG0409	Hydrogenase expression formation protein
XM56_RS03285	COG0309	Hydrogenase expression formation protein (HypE)
XM56_RS03290	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
XM56_RS03300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
XM56_RS03310	COG5001	Diguanylate cyclase
XM56_RS03330	COG0477	Major facilitator Superfamily
XM56_RS03345	COG1283	sodium-dependent phosphate transmembrane transporter activity
XM56_RS03355	COG1609	Transcriptional regulator
XM56_RS03360	COG0477	Major facilitator Superfamily
XM56_RS03375	COG0697	spore germination
XM56_RS03390	COG4607	ABC-type enterochelin transport system periplasmic component
XM56_RS03400	COG4605	iron ion homeostasis
XM56_RS03405	COG4604	ABC transporter, ATP-binding protein
XM56_RS03410	COG0024	Methionine aminopeptidase
XM56_RS03435	COG1289	transmembrane transporter activity
XM56_RS03445	COG1982	Orn Lys Arg decarboxylase major
XM56_RS03450	COG0531	amino acid
XM56_RS03490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XM56_RS03505	COG1982	Orn Lys Arg decarboxylase major
XM56_RS03515	COG0741	lytic transglycosylase activity
XM56_RS03520	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
XM56_RS03525	COG1194	a g-specific adenine glycosylase
XM56_RS03530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
XM56_RS03535	COG3171	Protein conserved in bacteria
XM56_RS03550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XM56_RS03555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
XM56_RS03560	COG1872	DUF167
XM56_RS03565	COG0762	integral membrane protein
XM56_RS03570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
XM56_RS03575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
XM56_RS03580	COG2805	Type II/IV secretion system protein
XM56_RS03590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XM56_RS03595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
XM56_RS03600	COG1678	Uncharacterized ACR, COG1678
XM56_RS03605	COG0189	ligase activity
XM56_RS03610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
XM56_RS03615	COG2356	endonuclease I
XM56_RS03620	COG3091	SprT-like family
XM56_RS03625	COG0640	Transcriptional regulator
XM56_RS03640	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
XM56_RS03645	COG1166	arginine decarboxylase activity
XM56_RS03655	COG0501	Belongs to the peptidase M48B family
XM56_RS03660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
XM56_RS03665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
XM56_RS03670	COG0126	phosphoglycerate kinase activity
XM56_RS03675	COG0191	fructose-bisphosphate aldolase activity
XM56_RS03695	COG1279	arginine transmembrane transporter activity
XM56_RS03705	COG0583	DNA-binding transcription factor activity
XM56_RS03710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
XM56_RS03715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XM56_RS03750	COG0602	queuosine metabolic process
XM56_RS03770	COG0720	synthase
XM56_RS03775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
XM56_RS03780	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
XM56_RS03785	COG0175	sulfate reduction
XM56_RS03800	COG2234	aminopeptidase activity
XM56_RS03805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
XM56_RS03805	COG1648	precorrin-2 dehydrogenase activity
XM56_RS03810	COG0175	sulfate reduction
XM56_RS03815	COG2895	sulfate adenylyltransferase (ATP) activity
XM56_RS03820	COG0529	Catalyzes the synthesis of activated sulfate
XM56_RS03830	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
XM56_RS03840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
XM56_RS03845	COG0585	pseudouridine synthase activity
XM56_RS03850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
XM56_RS03855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
XM56_RS03860	COG1388	LysM domain
XM56_RS03860	COG4942	peptidase
XM56_RS03865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
XM56_RS03870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
XM56_RS03900	COG3121	Chaperone
XM56_RS03910	COG3539	Fimbrial protein
XM56_RS03915	COG3539	Fimbrial protein
XM56_RS03945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS03955	COG1538	Outer membrane efflux protein
XM56_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS03985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XM56_RS03990	COG1858	cytochrome C peroxidase
XM56_RS04000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
XM56_RS04005	COG0640	Transcriptional regulator
XM56_RS04060	COG0410	ABC transporter
XM56_RS04065	COG1137	ATPase activity
XM56_RS04070	COG4177	L-phenylalanine transmembrane transporter activity
XM56_RS04085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
XM56_RS04085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
XM56_RS04090	COG0243	molybdopterin cofactor binding
XM56_RS04095	COG0437	4 iron, 4 sulfur cluster binding
XM56_RS04100	COG3302	dmso reductase anchor subunit
XM56_RS04105	COG3381	protein complex oligomerization
XM56_RS04125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
XM56_RS04130	COG2137	regulation of response to DNA damage stimulus
XM56_RS04135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XM56_RS04140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
XM56_RS04155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XM56_RS04160	COG1238	metal cluster binding
XM56_RS04165	COG2918	glutathione biosynthetic process
XM56_RS04170	COG1854	S-ribosylhomocysteine lyase activity
XM56_RS04180	COG4536	flavin adenine dinucleotide binding
XM56_RS04185	COG4137	Cytochrome C assembly protein
XM56_RS04190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
XM56_RS04195	COG0228	four-way junction DNA binding
XM56_RS04200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
XM56_RS04205	COG0336	Belongs to the RNA methyltransferase TrmD family
XM56_RS04210	COG0335	large ribosomal subunit rRNA binding
XM56_RS04215	COG3137	Salt-induced outer membrane protein
XM56_RS04220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
XM56_RS04225	COG3279	Response regulator of the LytR AlgR family
XM56_RS04230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XM56_RS04235	COG0287	Prephenate dehydrogenase
XM56_RS04235	COG1605	Chorismate mutase
XM56_RS04240	COG0077	Prephenate dehydratase
XM56_RS04240	COG1605	Chorismate mutase
XM56_RS04255	COG0542	response to heat
XM56_RS04265	COG0564	pseudouridine synthase activity
XM56_RS04270	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XM56_RS04275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
XM56_RS04305	COG5544	Lipoprotein
XM56_RS04310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XM56_RS04315	COG1042	CoA-binding domain protein
XM56_RS04315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XM56_RS04315	COG0045	succinate-CoA ligase (ADP-forming) activity
XM56_RS04320	COG3148	PFAM DTW domain containing protein
XM56_RS04325	COG3118	belongs to the thioredoxin family
XM56_RS04330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XM56_RS04345	COG2814	Major facilitator Superfamily
XM56_RS04350	COG1566	PFAM secretion protein HlyD family protein
XM56_RS04355	COG1538	Outer membrane efflux protein
XM56_RS04360	COG1846	Transcriptional regulator
XM56_RS04370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
XM56_RS04375	COG2814	Major facilitator Superfamily
XM56_RS04415	COG0765	amino acid transport
XM56_RS04420	COG0765	amino acid transport
XM56_RS04430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
XM56_RS04450	COG0436	Aminotransferase
XM56_RS04455	COG0235	Class ii aldolase
XM56_RS04460	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
XM56_RS04465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
XM56_RS04470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
XM56_RS04475	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
XM56_RS04490	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
XM56_RS04495	COG1960	acyl-CoA dehydrogenase activity
XM56_RS04505	COG0121	glutamine amidotransferase
XM56_RS04510	COG3034	peptidoglycan biosynthetic process
XM56_RS04515	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XM56_RS04520	COG1805	sodium ion transport
XM56_RS04525	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XM56_RS04530	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XM56_RS04535	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
XM56_RS04540	COG2871	sodium ion transport
XM56_RS04545	COG1477	protein flavinylation
XM56_RS04550	COG2991	Protein conserved in bacteria
XM56_RS04560	COG1181	Belongs to the D-alanine--D-alanine ligase family
XM56_RS04565	COG2964	Protein conserved in bacteria
XM56_RS04580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
XM56_RS04585	COG2195	Cleaves the N-terminal amino acid of tripeptides
XM56_RS04590	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
XM56_RS04595	COG1073	alpha beta
XM56_RS04605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
XM56_RS04610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
XM56_RS04615	COG2188	Transcriptional regulator
XM56_RS04635	COG3459	Glycosyltransferase 36 associated
XM56_RS04650	COG2226	methyltransferase
XM56_RS04675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
XM56_RS04680	COG3123	guanosine phosphorylase activity
XM56_RS04685	COG2974	May be involved in recombination
XM56_RS04690	COG1940	carbohydrate kinase activity
XM56_RS04695	COG0419	ATPase involved in DNA repair
XM56_RS04700	COG0420	3'-5' exonuclease activity
XM56_RS04705	COG0745	RESPONSE REGULATOR receiver
XM56_RS04710	COG5002	protein histidine kinase activity
XM56_RS04730	COG0366	Alpha amylase catalytic
XM56_RS04750	COG0450	alkyl hydroperoxide reductase
XM56_RS04755	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
XM56_RS04760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
XM56_RS04775	COG0343	queuine tRNA-ribosyltransferase activity
XM56_RS04780	COG1862	Preprotein translocase
XM56_RS04785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XM56_RS04790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
XM56_RS04810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
XM56_RS04815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XM56_RS04815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
XM56_RS04820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
XM56_RS04825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
XM56_RS04830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
XM56_RS04835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
XM56_RS04845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
XM56_RS04850	COG0142	geranyltranstransferase activity
XM56_RS04860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XM56_RS04860	COG0301	tRNA thio-modification
XM56_RS04870	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
XM56_RS04875	COG1666	GTP binding
XM56_RS04880	COG2814	Major facilitator Superfamily
XM56_RS04885	COG0109	protoheme IX farnesyltransferase activity
XM56_RS04890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
XM56_RS04895	COG1845	cytochrome c oxidase, subunit III
XM56_RS04900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
XM56_RS04905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
XM56_RS04915	COG2223	nitrite transmembrane transporter activity
XM56_RS04920	COG3056	Lipoprotein
XM56_RS04925	COG0271	Belongs to the BolA IbaG family
XM56_RS04935	COG0544	peptidyl-prolyl cis-trans isomerase activity
XM56_RS04940	COG0740	serine-type endopeptidase activity
XM56_RS04945	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
XM56_RS04950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
XM56_RS04955	COG0776	regulation of translation
XM56_RS04960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XM56_RS04965	COG1555	photosystem II stabilization
XM56_RS04970	COG0824	Thioesterase
XM56_RS04975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
XM56_RS04980	COG4533	DNA binding
XM56_RS04985	COG0561	phosphatase activity
XM56_RS04995	COG1522	sequence-specific DNA binding
XM56_RS05000	COG1132	(ABC) transporter
XM56_RS05005	COG1132	(ABC) transporter
XM56_RS05010	COG0347	Belongs to the P(II) protein family
XM56_RS05015	COG0004	ammonium transporteR
XM56_RS05020	COG1946	Acyl-CoA thioesterase
XM56_RS05025	COG3126	Type III secretion system lipoprotein chaperone (YscW)
XM56_RS05030	COG3695	enzyme binding
XM56_RS05055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XM56_RS05060	COG0803	Belongs to the bacterial solute-binding protein 9 family
XM56_RS05065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
XM56_RS05070	COG0254	rRNA binding
XM56_RS05085	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
XM56_RS05090	COG3457	Alanine racemase
XM56_RS05105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XM56_RS05110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS05115	COG1309	transcriptional regulator
XM56_RS05120	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
XM56_RS05125	COG1196	nuclear chromosome segregation
XM56_RS05125	COG3264	Mechanosensitive ion channel
XM56_RS05140	COG2832	Protein of unknown function (DUF454)
XM56_RS05145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
XM56_RS05155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
XM56_RS05160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
XM56_RS05165	COG0326	Molecular chaperone. Has ATPase activity
XM56_RS05170	COG0563	adenylate kinase activity
XM56_RS05175	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
XM56_RS05180	COG2244	polysaccharide biosynthetic process
XM56_RS05185	COG1216	Glycosyl transferase, family 2
XM56_RS05185	COG1442	glycosyl transferase family 8
XM56_RS05190	COG1215	transferase activity, transferring glycosyl groups
XM56_RS05195	COG0438	transferase activity, transferring glycosyl groups
XM56_RS05200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XM56_RS05205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XM56_RS05225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XM56_RS05230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XM56_RS05230	COG4651	solute:proton antiporter activity
XM56_RS05235	COG2223	nitrite transmembrane transporter activity
XM56_RS05240	COG0737	Belongs to the 5'-nucleotidase family
XM56_RS05250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
XM56_RS05255	COG3735	TraB family
XM56_RS05260	COG2217	Heavy metal translocating P-type atpase
XM56_RS05265	COG0789	Transcriptional regulator
XM56_RS05270	COG1585	Membrane protein implicated in regulation of membrane protease activity
XM56_RS05275	COG0330	HflC and HflK could
XM56_RS05280	COG3118	belongs to the thioredoxin family
XM56_RS05285	COG0300	oxidoreductase activity
XM56_RS05290	COG2755	lipolytic protein G-D-S-L family
XM56_RS05295	COG4181	ATPase activity
XM56_RS05300	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
XM56_RS05305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
XM56_RS05310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
XM56_RS05315	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XM56_RS05320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
XM56_RS05325	COG0215	cysteine-tRNA ligase activity
XM56_RS05330	COG2501	S4 domain
XM56_RS05335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
XM56_RS05345	COG0582	viral genome integration into host DNA
XM56_RS05385	COG2850	peptidyl-arginine hydroxylation
XM56_RS05390	COG2986	histidine ammonia-lyase
XM56_RS05400	COG5265	(ABC) transporter
XM56_RS05415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XM56_RS05425	COG2197	response regulator
XM56_RS05430	COG1278	Cold shock
XM56_RS05445	COG3706	GGDEF domain
XM56_RS05450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XM56_RS05455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
XM56_RS05460	COG0321	lipoyl(octanoyl) transferase activity
XM56_RS05465	COG2921	Belongs to the UPF0250 family
XM56_RS05470	COG1686	Belongs to the peptidase S11 family
XM56_RS05475	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XM56_RS05480	COG0772	Belongs to the SEDS family
XM56_RS05485	COG0768	penicillin binding
XM56_RS05495	COG0799	negative regulation of ribosome biogenesis
XM56_RS05500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
XM56_RS05505	COG1466	dna polymerase III delta subunit
XM56_RS05510	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
XM56_RS05515	COG0495	leucyl-tRNA aminoacylation
XM56_RS05520	COG2888	peptidyl-tyrosine sulfation
XM56_RS05525	COG1126	abc transporter atp-binding protein
XM56_RS05530	COG0765	amino acid transport
XM56_RS05535	COG0765	amino acid transport
XM56_RS05550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
XM56_RS05555	COG4535	Mg2 and Co2 transporter CorC
XM56_RS05560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
XM56_RS05565	COG1702	phosphate starvation-inducible protein PhoH
XM56_RS05570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
XM56_RS05575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XM56_RS05590	COG0367	asparagine synthase
XM56_RS05595	COG0647	UMP catabolic process
XM56_RS05600	COG1846	Transcriptional regulator
XM56_RS05600	COG1940	carbohydrate kinase activity
XM56_RS05605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
XM56_RS05610	COG0363	glucosamine-6-phosphate deaminase activity
XM56_RS05615	COG1263	PTS System
XM56_RS05615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS05615	COG2190	(PTS) system
XM56_RS05620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XM56_RS05640	COG0735	belongs to the Fur family
XM56_RS05650	COG0840	transmembrane signaling receptor activity
XM56_RS05660	COG0596	Alpha beta hydrolase
XM56_RS05665	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
XM56_RS05670	COG0033	Phosphoglucomutase
XM56_RS05685	COG0745	RESPONSE REGULATOR receiver
XM56_RS05690	COG2205	protein histidine kinase activity
XM56_RS05695	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
XM56_RS05700	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
XM56_RS05705	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
XM56_RS05725	COG2994	toxin metabolic process
XM56_RS05730	COG3064	Membrane
XM56_RS05730	COG3064	Membrane
XM56_RS05730	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XM56_RS05730	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
XM56_RS05730	COG1073	alpha beta
XM56_RS05730	COG1073	alpha beta
XM56_RS05735	COG3272	Protein of unknown function (DUF1722)
XM56_RS05745	COG5212	phosphodiesterase
XM56_RS05750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
XM56_RS05755	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
XM56_RS05760	COG1984	allophanate hydrolase subunit 2
XM56_RS05765	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
XM56_RS05780	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
XM56_RS05790	COG2009	succinate dehydrogenase
XM56_RS05795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
XM56_RS05800	COG1053	succinate dehydrogenase
XM56_RS05810	COG0567	Dehydrogenase, E1 component
XM56_RS05815	COG0508	dehydrogenase complex catalyzes the overall conversion of
XM56_RS05820	COG0045	succinate-CoA ligase (ADP-forming) activity
XM56_RS05825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
XM56_RS05835	COG0737	Belongs to the 5'-nucleotidase family
XM56_RS05840	COG1271	oxidase subunit
XM56_RS05845	COG1294	oxidase, subunit
XM56_RS05850	COG4890	Cyd operon protein YbgT
XM56_RS05855	COG3790	cyd operon protein YbgE
XM56_RS05860	COG0824	Thioesterase
XM56_RS05865	COG0811	peptide transport
XM56_RS05870	COG0848	biopolymer transport protein
XM56_RS05875	COG3064	Membrane
XM56_RS05875	COG3064	Membrane
XM56_RS05880	COG0823	Involved in the tonB-independent uptake of proteins
XM56_RS05885	COG2885	chlorophyll binding
XM56_RS05890	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
XM56_RS05900	COG0582	viral genome integration into host DNA
XM56_RS05905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
XM56_RS05915	COG1230	cation diffusion facilitator family transporter
XM56_RS05920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
XM56_RS05925	COG0588	phosphoglycerate mutase activity
XM56_RS05950	COG2017	converts alpha-aldose to the beta-anomer
XM56_RS05955	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
XM56_RS05960	COG1085	galactose-1-phosphate uridylyltransferase
XM56_RS05965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
XM56_RS05975	COG1119	ATPase activity
XM56_RS05980	COG2005	Transcriptional regulator
XM56_RS05980	COG3585	molybdate ion transport
XM56_RS05990	COG0725	ABC transporter, periplasmic molybdate-binding protein
XM56_RS05995	COG0582	viral genome integration into host DNA
XM56_RS06175	COG3772	lysozyme
XM56_RS06185	COG4149	molybdate abc transporter
XM56_RS06195	COG0561	phosphatase activity
XM56_RS06200	COG2706	6-phosphogluconolactonase activity
XM56_RS06210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
XM56_RS06215	COG0156	8-amino-7-oxononanoate synthase activity
XM56_RS06220	COG2226	methyltransferase
XM56_RS06235	COG0556	nucleotide-excision repair
XM56_RS06240	COG4628	conserved protein (DUF2132)
XM56_RS06245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
XM56_RS06250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
XM56_RS06255	COG0315	cyclic pyranopterin monophosphate synthase activity
XM56_RS06260	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
XM56_RS06265	COG0314	molybdopterin synthase activity
XM56_RS06270	COG0670	Belongs to the BI1 family
XM56_RS06275	COG0842	Transport permease protein
XM56_RS06280	COG0842	Transport permease protein
XM56_RS06285	COG1131	(ABC) transporter
XM56_RS06290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS06295	COG1309	transcriptional regulator
XM56_RS06300	COG0513	Belongs to the DEAD box helicase family
XM56_RS06305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
XM56_RS06315	COG2239	Acts as a magnesium transporter
XM56_RS06320	COG1686	Belongs to the peptidase S11 family
XM56_RS06325	COG0277	FAD linked oxidase domain protein
XM56_RS06345	COG2261	transglycosylase associated protein
XM56_RS06355	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
XM56_RS06370	COG4807	Protein conserved in bacteria
XM56_RS06390	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
XM56_RS06400	COG2897	thiosulfate sulfurtransferase activity
XM56_RS06415	COG1732	Glycine betaine
XM56_RS06420	COG1174	glycine betaine transport
XM56_RS06425	COG1125	glycine betaine transport
XM56_RS06430	COG1174	glycine betaine transport
XM56_RS06440	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS06445	COG0583	DNA-binding transcription factor activity
XM56_RS06455	COG0697	spore germination
XM56_RS06475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XM56_RS06480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
XM56_RS06500	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
XM56_RS06510	COG1126	abc transporter atp-binding protein
XM56_RS06515	COG0765	amino acid transport
XM56_RS06520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS06525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
XM56_RS06530	COG0783	Belongs to the Dps family
XM56_RS06535	COG4106	trans-aconitate 2-methyltransferase activity
XM56_RS06550	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
XM56_RS06570	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
XM56_RS06590	COG0488	(ABC) transporter
XM56_RS06600	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XM56_RS06605	COG0303	'Molybdopterin
XM56_RS06620	COG1136	(ABC) transporter
XM56_RS06620	COG0577	efflux transmembrane transporter activity
XM56_RS06650	COG0583	DNA-binding transcription factor activity
XM56_RS06655	COG0477	Major facilitator Superfamily
XM56_RS06660	COG0302	gtp cyclohydrolase
XM56_RS06665	COG2311	Membrane
XM56_RS06690	COG3604	Transcriptional regulator
XM56_RS06695	COG3383	formate dehydrogenase (NAD+) activity
XM56_RS06700	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
XM56_RS06705	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
XM56_RS06715	COG3260	NADH ubiquinone oxidoreductase 20
XM56_RS06720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS06725	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
XM56_RS06725	COG3261	NADH dehydrogenase
XM56_RS06730	COG0651	ATP synthesis coupled electron transport
XM56_RS06735	COG4237	Hydrogenase 4 membrane
XM56_RS06740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XM56_RS06745	COG0650	Formate hydrogenlyase subunit 4
XM56_RS06750	COG0651	ATP synthesis coupled electron transport
XM56_RS06755	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
XM56_RS06760	COG0375	protein maturation
XM56_RS06765	COG0298	carbon dioxide binding
XM56_RS06770	COG2949	membrane
XM56_RS06775	COG0281	malic enzyme
XM56_RS06790	COG1346	cytolysis
XM56_RS06795	COG1380	Effector of murein hydrolase LrgA
XM56_RS06800	COG2814	Major facilitator Superfamily
XM56_RS06820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XM56_RS06820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
XM56_RS06825	COG0489	protein tyrosine kinase activity
XM56_RS06830	COG0572	uridine kinase
XM56_RS06840	COG2982	Protein involved in outer membrane biogenesis
XM56_RS06845	COG3069	C4-dicarboxylate transmembrane transporter activity
XM56_RS06850	COG1253	flavin adenine dinucleotide binding
XM56_RS06865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XM56_RS06870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
XM56_RS06875	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
XM56_RS06880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XM56_RS06905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XM56_RS06915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
XM56_RS06920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
XM56_RS06920	COG0140	phosphoribosyl-ATP diphosphatase activity
XM56_RS06925	COG0107	imidazoleglycerol-phosphate synthase activity
XM56_RS06930	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
XM56_RS06940	COG0131	Imidazoleglycerol-phosphate dehydratase
XM56_RS06940	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XM56_RS06945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XM56_RS06955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
XM56_RS06960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XM56_RS06970	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS06975	COG1129	ABC transporter
XM56_RS06990	COG0531	amino acid
XM56_RS06995	COG2925	Exonuclease
XM56_RS07000	COG3320	Male sterility
XM56_RS07000	COG1022	Amp-dependent synthetase and ligase
XM56_RS07005	COG1289	transmembrane transporter activity
XM56_RS07010	COG2926	Belongs to the UPF0265 family
XM56_RS07020	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS07025	COG1129	ABC transporter
XM56_RS07040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
XM56_RS07050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XM56_RS07070	COG4656	Part of a membrane complex involved in electron transport
XM56_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
XM56_RS07090	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
XM56_RS07165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
XM56_RS07175	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
XM56_RS07240	COG1492	cobalamin metabolic process
XM56_RS07260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
XM56_RS07330	COG3121	Chaperone
XM56_RS07335	COG3188	usher protein
XM56_RS07405	COG0137	argininosuccinate synthase activity
XM56_RS07410	COG0534	Mate efflux family protein
XM56_RS07420	COG0352	thiamine-phosphate diphosphorylase activity
XM56_RS07425	COG0561	phosphatase activity
XM56_RS07430	COG1349	DNA-binding transcription factor activity
XM56_RS07440	COG0784	Response regulator, receiver
XM56_RS07440	COG0835	chemotaxis
XM56_RS07450	COG4221	oxidoreductase activity
XM56_RS07470	COG3842	ATPase activity
XM56_RS07480	COG1840	ABC-type Fe3 transport system, periplasmic component
XM56_RS07485	COG2271	Major facilitator Superfamily
XM56_RS07500	COG4565	transcriptional regulatory protein
XM56_RS07505	COG3290	protein histidine kinase activity
XM56_RS07515	COG3052	prosthetic group binding
XM56_RS07520	COG2301	Belongs to the HpcH HpaI aldolase family
XM56_RS07525	COG3051	citrate lyase alpha subunit
XM56_RS07530	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
XM56_RS07530	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
XM56_RS07540	COG0471	metal ion transport
XM56_RS07555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
XM56_RS07575	COG2814	Major facilitator Superfamily
XM56_RS07580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS07580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS07585	COG3122	Protein conserved in bacteria
XM56_RS07605	COG3121	Chaperone
XM56_RS07630	COG2205	protein histidine kinase activity
XM56_RS07630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS07645	COG3228	Belongs to the MtfA family
XM56_RS07655	COG1070	Carbohydrate kinase
XM56_RS07680	COG3121	Chaperone
XM56_RS07720	COG3321	synthase
XM56_RS07720	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS07720	COG0604	alcohol dehydrogenase
XM56_RS07725	COG3328	transposase activity
XM56_RS07730	COG3250	beta-galactosidase activity
XM56_RS07735	COG1609	Transcriptional regulator
XM56_RS07750	COG0840	transmembrane signaling receptor activity
XM56_RS07765	COG1285	pathogenesis
XM56_RS07775	COG2130	NADP-dependent
XM56_RS07780	COG0589	response to stress
XM56_RS07800	COG1360	Flagellar Motor Protein
XM56_RS07805	COG2198	Histidine kinase
XM56_RS07805	COG0643	Histidine kinase
XM56_RS07810	COG0835	chemotaxis
XM56_RS07815	COG0840	transmembrane signaling receptor activity
XM56_RS07820	COG0840	transmembrane signaling receptor activity
XM56_RS07825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
XM56_RS07835	COG0745	RESPONSE REGULATOR receiver
XM56_RS07840	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
XM56_RS07845	COG1404	Belongs to the peptidase S8 family
XM56_RS07845	COG4935	Belongs to the peptidase S8 family
XM56_RS07850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XM56_RS07855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
XM56_RS07870	COG3418	PFAM FlgN family protein
XM56_RS07875	COG2747	anti-sigma28 factor FlgM
XM56_RS07885	COG1815	bacterial-type flagellum-dependent cell motility
XM56_RS07890	COG1558	bacterial-type flagellum-dependent cell motility
XM56_RS07895	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
XM56_RS07930	COG1256	bacterial-type flagellum assembly
XM56_RS07950	COG1338	Plays a role in the flagellum-specific transport system
XM56_RS07970	COG1580	Controls the rotational direction of flagella during chemotaxis
XM56_RS07990	COG1317	bacterial-type flagellum organization
XM56_RS08005	COG1677	Flagellar hook-basal body complex protein FliE
XM56_RS08040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
XM56_RS08045	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
XM56_RS08085	COG1191	sigma factor activity
XM56_RS08095	COG2515	1-aminocyclopropane-1-carboxylate deaminase
XM56_RS08100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS08105	COG0765	amino acid transport
XM56_RS08110	COG1126	abc transporter atp-binding protein
XM56_RS08125	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XM56_RS08125	COG0506	proline dehydrogenase activity
XM56_RS08125	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
XM56_RS08140	COG3157	Type VI secretion system effector, Hcp
XM56_RS08150	COG0672	)-iron permease
XM56_RS08155	COG2822	iron ion transport
XM56_RS08165	COG0655	NAD(P)H dehydrogenase (quinone) activity
XM56_RS08175	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
XM56_RS08190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
XM56_RS08195	COG0778	Nitroreductase
XM56_RS08200	COG2267	carboxylic ester hydrolase activity
XM56_RS08205	COG0251	oxidation-reduction process
XM56_RS08210	COG1335	isochorismatase
XM56_RS08215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XM56_RS08220	COG1309	transcriptional regulator
XM56_RS08225	COG1113	amino acid transport
XM56_RS08235	COG0582	viral genome integration into host DNA
XM56_RS08240	COG2963	transposase activity
XM56_RS08250	COG2226	methyltransferase
XM56_RS08265	COG0366	Alpha amylase catalytic
XM56_RS08275	COG3136	membrane protein required for alginate biosynthesis
XM56_RS08285	COG2197	response regulator
XM56_RS08290	COG0322	excinuclease ABC activity
XM56_RS08295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
XM56_RS08380	COG3077	Addiction module antitoxin, RelB DinJ family
XM56_RS08385	COG3041	Addiction module toxin RelE StbE family
XM56_RS08475	COG2963	transposase activity
XM56_RS08485	COG3328	transposase activity
XM56_RS08530	COG3772	lysozyme
XM56_RS08535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
XM56_RS08540	COG2979	Protein of unknown function (DUF533)
XM56_RS08555	COG0012	GTP binding
XM56_RS08565	COG0193	aminoacyl-tRNA hydrolase activity
XM56_RS08580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
XM56_RS08590	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
XM56_RS08595	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
XM56_RS08600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
XM56_RS08605	COG2890	protein-(glutamine-N5) methyltransferase activity
XM56_RS08620	COG2877	3-deoxy-8-phosphooctulonate synthase activity
XM56_RS08630	COG3706	GGDEF domain
XM56_RS08650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XM56_RS08655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
XM56_RS08660	COG3381	protein complex oligomerization
XM56_RS08670	COG0477	Major facilitator Superfamily
XM56_RS08685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XM56_RS08695	COG0673	inositol 2-dehydrogenase activity
XM56_RS08700	COG0728	peptidoglycan biosynthetic process
XM56_RS08705	COG0387	Pfam Sodium calcium exchanger
XM56_RS08720	COG0583	DNA-binding transcription factor activity
XM56_RS08725	COG3850	Histidine kinase
XM56_RS08730	COG1294	oxidase, subunit
XM56_RS08735	COG1271	oxidase subunit
XM56_RS08740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XM56_RS08745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
XM56_RS08750	COG3138	arginine N-succinyltransferase
XM56_RS08760	COG3724	N-succinylarginine dihydrolase activity
XM56_RS08765	COG2988	succinylglutamate desuccinylase activity
XM56_RS08795	COG1228	amidohydrolase
XM56_RS08805	COG0402	S-adenosylhomocysteine deaminase activity
XM56_RS08815	COG3443	Belongs to the bacterial solute-binding protein 9 family
XM56_RS08840	COG4942	peptidase
XM56_RS08850	COG2222	sugar isomerase
XM56_RS08855	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS08860	COG3716	PTS system mannose fructose sorbose family IID component
XM56_RS08870	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS08880	COG1349	DNA-binding transcription factor activity
XM56_RS08900	COG1187	pseudouridine synthase activity
XM56_RS08905	COG0786	glutamate:sodium symporter activity
XM56_RS08925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XM56_RS08930	COG2226	methyltransferase
XM56_RS08935	COG3788	relative of glutathione S-transferase, MAPEG superfamily
XM56_RS08940	COG1801	Protein of unknown function DUF72
XM56_RS08945	COG1335	isochorismatase
XM56_RS08950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
XM56_RS08955	COG0494	nUDIX hydrolase
XM56_RS08960	COG0217	transcriptional regulatory protein
XM56_RS08965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
XM56_RS08970	COG0632	four-way junction helicase activity
XM56_RS08975	COG2255	four-way junction helicase activity
XM56_RS08980	COG3104	oligopeptide transport
XM56_RS08985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XM56_RS08990	COG1121	(ABC) transporter
XM56_RS08995	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
XM56_RS09000	COG0739	heme binding
XM56_RS09005	COG1560	Kdo2-lipid A biosynthetic process
XM56_RS09015	COG3328	transposase activity
XM56_RS09020	COG0469	pyruvate kinase activity
XM56_RS09025	COG1737	Transcriptional regulator
XM56_RS09030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
XM56_RS09035	COG0800	Aldolase
XM56_RS09040	COG2076	Multidrug Resistance protein
XM56_RS09045	COG2076	Multidrug Resistance protein
XM56_RS09050	COG0251	oxidation-reduction process
XM56_RS09055	COG1199	ATP-dependent helicase activity
XM56_RS09065	COG3065	identical protein binding
XM56_RS09070	COG0318	PFAM AMP-dependent synthetase and ligase
XM56_RS09075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
XM56_RS09080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
XM56_RS09085	COG2894	cell division
XM56_RS09090	COG0850	regulation of cytokinetic process
XM56_RS09100	COG3100	YcgL domain-containing protein
XM56_RS09105	COG2951	lytic endotransglycosylase activity
XM56_RS09110	COG0179	Fumarylacetoacetate (FAA) hydrolase
XM56_RS09115	COG2983	Belongs to the UPF0260 family
XM56_RS09140	COG0668	transmembrane transport
XM56_RS09145	COG0625	glutathione transferase activity
XM56_RS09170	COG2203	Gaf domain
XM56_RS09170	COG3706	GGDEF domain
XM56_RS09170	COG4251	negative regulation of phosphorylation
XM56_RS09170	COG5001	Diguanylate cyclase
XM56_RS09205	COG2814	Major facilitator Superfamily
XM56_RS09215	COG3008	intermembrane lipid transfer
XM56_RS09220	COG2995	paraquat-inducible protein a
XM56_RS09225	COG1956	GAF domain-containing protein
XM56_RS09235	COG0793	Belongs to the peptidase S41A family
XM56_RS09240	COG0501	Belongs to the peptidase M48B family
XM56_RS09255	COG0823	Involved in the tonB-independent uptake of proteins
XM56_RS09265	COG3023	N-Acetylmuramoyl-L-alanine amidase
XM56_RS09270	COG1823	symporter activity
XM56_RS09275	COG1988	membrane-bound metal-dependent
XM56_RS09285	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XM56_RS09290	COG1653	transport
XM56_RS09295	COG3842	ATPase activity
XM56_RS09300	COG0395	ABC-type sugar transport system, permease component
XM56_RS09305	COG1175	transmembrane transport
XM56_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS09320	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
XM56_RS09325	COG1917	Cupin 2, conserved barrel domain protein
XM56_RS09330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XM56_RS09340	COG0583	DNA-binding transcription factor activity
XM56_RS09345	COG0427	acetyl-CoA hydrolase
XM56_RS09350	COG1024	Enoyl-CoA hydratase
XM56_RS09355	COG1703	isobutyryl-CoA mutase activity
XM56_RS09360	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XM56_RS09360	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
XM56_RS09365	COG3001	Fructosamine kinase
XM56_RS09370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XM56_RS09375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
XM56_RS09380	COG1121	(ABC) transporter
XM56_RS09385	COG0803	Belongs to the bacterial solute-binding protein 9 family
XM56_RS09420	COG1811	Na channel or pump
XM56_RS09425	COG4249	Peptidase C14 caspase catalytic subunit p20
XM56_RS09430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
XM56_RS09435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
XM56_RS09440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
XM56_RS09445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
XM56_RS09450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
XM56_RS09460	COG0776	regulation of translation
XM56_RS09465	COG2314	TM2 domain
XM56_RS09475	COG4139	cobalamin transport
XM56_RS09480	COG0386	Belongs to the glutathione peroxidase family
XM56_RS09485	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
XM56_RS09490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XM56_RS09495	COG0463	Glycosyl transferase, family 2
XM56_RS09500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
XM56_RS09500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XM56_RS09505	COG0726	polysaccharide deacetylase
XM56_RS09510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
XM56_RS09515	COG2076	Multidrug Resistance protein
XM56_RS09520	COG2076	Multidrug Resistance protein
XM56_RS09525	COG0791	NLP P60 protein
XM56_RS09530	COG0095	Lipoate-protein ligase
XM56_RS09540	COG4558	Periplasmic binding protein
XM56_RS09545	COG3720	iron ion transport
XM56_RS09565	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
XM56_RS09570	COG0574	Belongs to the PEP-utilizing enzyme family
XM56_RS09570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XM56_RS09575	COG0628	permease
XM56_RS09580	COG0247	lactate metabolic process
XM56_RS09580	COG0277	FAD linked oxidase domain protein
XM56_RS09590	COG2050	protein possibly involved in aromatic compounds catabolism
XM56_RS09595	COG0316	Belongs to the HesB IscA family
XM56_RS09600	COG0719	Fe-S assembly protein
XM56_RS09605	COG0396	ATPase activity
XM56_RS09610	COG0719	Fe-S assembly protein
XM56_RS09620	COG2166	iron-sulfur cluster assembly
XM56_RS09625	COG1388	LysM domain
XM56_RS09625	COG1376	ErfK ybiS ycfS ynhG family protein
XM56_RS09645	COG0534	Mate efflux family protein
XM56_RS09650	COG0307	riboflavin synthase, alpha
XM56_RS09655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
XM56_RS09660	COG2814	Major facilitator Superfamily
XM56_RS09665	COG0583	DNA-binding transcription factor activity
XM56_RS09670	COG1609	Transcriptional regulator
XM56_RS09680	COG0791	NLP P60 protein
XM56_RS09685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
XM56_RS09690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XM56_RS09695	COG0346	lactoylglutathione lyase activity
XM56_RS09700	COG1902	pentaerythritol trinitrate reductase activity
XM56_RS09705	COG1309	transcriptional regulator
XM56_RS09710	COG2194	sulfuric ester hydrolase activity
XM56_RS09715	COG3313	Fe-S protein
XM56_RS09720	COG4989	oxidoreductase activity
XM56_RS09725	COG1289	transmembrane transporter activity
XM56_RS09730	COG1566	PFAM secretion protein HlyD family protein
XM56_RS09740	COG1846	Transcriptional regulator
XM56_RS09745	COG3133	Outer membrane lipoprotein
XM56_RS09750	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
XM56_RS09755	COG3895	Periplasmic Protein
XM56_RS09760	COG0259	pyridoxamine-phosphate oxidase activity
XM56_RS09765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
XM56_RS09775	COG0625	glutathione transferase activity
XM56_RS09795	COG3104	oligopeptide transport
XM56_RS09815	COG4172	Belongs to the ABC transporter superfamily
XM56_RS09825	COG4171	peptide transport system, permease
XM56_RS09830	COG4168	peptide transport system, permease
XM56_RS09835	COG4166	transmembrane transport
XM56_RS09850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
XM56_RS09855	COG1842	Phage shock protein A
XM56_RS09865	COG1983	PspC domain protein
XM56_RS09875	COG3106	COG3106 Predicted ATPase
XM56_RS09880	COG3768	UPF0283 membrane protein
XM56_RS09885	COG5654	RES domain protein
XM56_RS09890	COG5642	Protein of unknown function (DUF2384)
XM56_RS09900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
XM56_RS09905	COG4948	Mandelate Racemase Muconate Lactonizing
XM56_RS09910	COG2866	Carboxypeptidase
XM56_RS09915	COG4166	transmembrane transport
XM56_RS09920	COG0598	Magnesium transport protein CorA
XM56_RS09925	COG0037	tRNA processing
XM56_RS09930	COG0823	Involved in the tonB-independent uptake of proteins
XM56_RS09935	COG0674	pyruvate-flavodoxin oxidoreductase activity
XM56_RS09935	COG1013	pyruvate-flavodoxin oxidoreductase activity
XM56_RS09935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS09935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
XM56_RS09945	COG1285	pathogenesis
XM56_RS09950	COG3042	response to heat
XM56_RS09955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XM56_RS09960	COG2911	Protein conserved in bacteria
XM56_RS09970	COG3784	Protein of unknown function (DUF1318)
XM56_RS09975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
XM56_RS09980	COG1643	Atp-dependent helicase
XM56_RS09995	COG3591	Belongs to the peptidase S1B family
XM56_RS10005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
XM56_RS10010	COG2205	protein histidine kinase activity
XM56_RS10015	COG0745	RESPONSE REGULATOR receiver
XM56_RS10025	COG0531	amino acid
XM56_RS10040	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
XM56_RS10045	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
XM56_RS10050	COG0589	response to stress
XM56_RS10055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
XM56_RS10060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XM56_RS10075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
XM56_RS10080	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS10090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XM56_RS10095	COG0738	Major facilitator superfamily
XM56_RS10110	COG1011	Hydrolase
XM56_RS10115	COG0440	acetolactate synthase activity
XM56_RS10120	COG0028	Belongs to the TPP enzyme family
XM56_RS10130	COG3023	N-Acetylmuramoyl-L-alanine amidase
XM56_RS10160	COG2271	Major facilitator Superfamily
XM56_RS10165	COG0483	inositol monophosphate 1-phosphatase activity
XM56_RS10175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XM56_RS10190	COG3177	Filamentation induced by cAMP protein fic
XM56_RS10220	COG4215	(ABC) transporter
XM56_RS10230	COG1522	sequence-specific DNA binding
XM56_RS10260	COG0625	glutathione transferase activity
XM56_RS10360	COG4221	oxidoreductase activity
XM56_RS10365	COG1742	UPF0060 membrane protein
XM56_RS10395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
XM56_RS10400	COG1940	carbohydrate kinase activity
XM56_RS10405	COG0583	DNA-binding transcription factor activity
XM56_RS10410	COG2814	Major facilitator Superfamily
XM56_RS10450	COG0114	fumarate hydratase activity
XM56_RS10460	COG5339	Protein conserved in bacteria
XM56_RS10470	COG1609	Transcriptional regulator
XM56_RS10475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS10475	COG1263	PTS System
XM56_RS10480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
XM56_RS10485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
XM56_RS10490	COG0385	Bile acid
XM56_RS10495	COG0673	inositol 2-dehydrogenase activity
XM56_RS10505	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS10510	COG1129	ABC transporter
XM56_RS10515	COG1879	ABC-type sugar transport system periplasmic component
XM56_RS10525	COG2160	L-arabinose isomerase activity
XM56_RS10530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
XM56_RS10535	COG2274	protein secretion by the type I secretion system
XM56_RS10550	COG2759	Belongs to the formate--tetrahydrofolate ligase family
XM56_RS10560	COG4657	Part of a membrane complex involved in electron transport
XM56_RS10570	COG4656	Part of a membrane complex involved in electron transport
XM56_RS10580	COG2207	Transcriptional regulator
XM56_RS10580	COG3708	Transcriptional regulator
XM56_RS10585	COG4658	electron transport chain
XM56_RS10590	COG4659	FMN binding
XM56_RS10600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
XM56_RS10620	COG0243	molybdopterin cofactor binding
XM56_RS10625	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
XM56_RS10630	COG1966	Carbon starvation protein
XM56_RS10635	COG2879	small protein
XM56_RS10640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XM56_RS10645	COG1349	DNA-binding transcription factor activity
XM56_RS10670	COG0023	Translation Initiation Factor
XM56_RS10675	COG0284	orotidine-5'-phosphate decarboxylase activity
XM56_RS10685	COG3135	benzoate transporter
XM56_RS10690	COG1396	sequence-specific DNA binding
XM56_RS10700	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
XM56_RS10705	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
XM56_RS10710	COG0671	phosphoesterase, PA-phosphatase related
XM56_RS10735	COG0583	DNA-binding transcription factor activity
XM56_RS10750	COG0616	signal peptide processing
XM56_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS10760	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
XM56_RS10770	COG1187	pseudouridine synthase activity
XM56_RS10775	COG0009	L-threonylcarbamoyladenylate synthase
XM56_RS10780	COG0613	PHP domain protein
XM56_RS10790	COG0512	Glutamine amidotransferase of anthranilate synthase
XM56_RS10800	COG0135	phosphoribosylanthranilate isomerase activity
XM56_RS10800	COG0134	indole-3-glycerol-phosphate synthase activity
XM56_RS10805	COG0133	tryptophan synthase activity
XM56_RS10810	COG0159	tryptophan synthase activity
XM56_RS10820	COG3047	cAMP biosynthetic process
XM56_RS10825	COG0727	PFAM Uncharacterised protein family (UPF0153)
XM56_RS10840	COG2917	probably involved in intracellular septation
XM56_RS10845	COG1607	acyl-coa hydrolase
XM56_RS10850	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
XM56_RS10855	COG2350	Protein conserved in bacteria
XM56_RS10870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XM56_RS10875	COG3099	Belongs to the UPF0263 family
XM56_RS10885	COG0444	Belongs to the ABC transporter superfamily
XM56_RS10890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XM56_RS10910	COG2095	MarC family integral membrane protein
XM56_RS10915	COG1012	belongs to the aldehyde dehydrogenase family
XM56_RS10915	COG1454	alcohol dehydrogenase
XM56_RS10930	COG2916	Histone family protein nucleoid-structuring protein H-NS
XM56_RS10940	COG0745	RESPONSE REGULATOR receiver
XM56_RS10945	COG1752	Esterase of the alpha-beta hydrolase superfamily
XM56_RS10955	COG3012	SEC-C Motif Domain Protein
XM56_RS10960	COG0788	formyltetrahydrofolate deformylase activity
XM56_RS10970	COG0583	DNA-binding transcription factor activity
XM56_RS10975	COG0708	Exodeoxyribonuclease III
XM56_RS10980	COG0494	nUDIX hydrolase
XM56_RS10990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
XM56_RS11000	COG0778	Nitroreductase
XM56_RS11005	COG0616	signal peptide processing
XM56_RS11010	COG0252	asparaginase activity
XM56_RS11015	COG1335	isochorismatase
XM56_RS11025	COG3139	Protein of unknown function (DUF1315)
XM56_RS11030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XM56_RS11045	COG3713	MltA-interacting MipA family protein
XM56_RS11050	COG2766	serine protein kinase
XM56_RS11055	COG2718	Belongs to the UPF0229 family
XM56_RS11070	COG0583	DNA-binding transcription factor activity
XM56_RS11080	COG2199	diguanylate cyclase activity
XM56_RS11080	COG2200	EAL domain
XM56_RS11080	COG2202	Pas domain
XM56_RS11085	COG2814	Major facilitator Superfamily
XM56_RS11090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
XM56_RS11095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XM56_RS11100	COG2719	SpoVR family
XM56_RS11105	COG2186	Transcriptional regulator
XM56_RS11110	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XM56_RS11115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
XM56_RS11135	COG3142	Participates in the control of copper homeostasis
XM56_RS11140	COG3102	Protein conserved in bacteria
XM56_RS11145	COG0018	arginyl-trna synthetase
XM56_RS11155	COG1702	phosphate starvation-inducible protein PhoH
XM56_RS11170	COG3658	cytochrome
XM56_RS11175	COG1215	transferase activity, transferring glycosyl groups
XM56_RS11180	COG0726	polysaccharide deacetylase
XM56_RS11180	COG1649	PFAM Uncharacterised BCR, COG1649
XM56_RS11190	COG0006	proline dipeptidase activity
XM56_RS11195	COG4114	ferric iron reductase
XM56_RS11200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
XM56_RS11225	COG0577	efflux transmembrane transporter activity
XM56_RS11225	COG1136	(ABC) transporter
XM56_RS11235	COG0577	efflux transmembrane transporter activity
XM56_RS11235	COG1136	(ABC) transporter
XM56_RS11250	COG0672	)-iron permease
XM56_RS11265	COG2066	Belongs to the glutaminase family
XM56_RS11270	COG3622	Belongs to the hyi family
XM56_RS11275	COG0235	Class ii aldolase
XM56_RS11280	COG3395	kinase activity
XM56_RS11285	COG1349	DNA-binding transcription factor activity
XM56_RS11290	COG3290	protein histidine kinase activity
XM56_RS11295	COG4565	transcriptional regulatory protein
XM56_RS11300	COG3493	citrate carrier protein
XM56_RS11320	COG2223	nitrite transmembrane transporter activity
XM56_RS11325	COG0561	phosphatase activity
XM56_RS11335	COG3328	transposase activity
XM56_RS11340	COG0500	methyltransferase
XM56_RS11350	COG3328	transposase activity
XM56_RS11395	COG4974	Belongs to the 'phage' integrase family
XM56_RS11405	COG1276	copper resistance
XM56_RS11410	COG2372	response to copper ion
XM56_RS11415	COG1528	Iron-storage protein
XM56_RS11430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
XM56_RS11435	COG1770	oligopeptidase
XM56_RS11445	COG3097	Belongs to the UPF0267 family
XM56_RS11450	COG3141	response to X-ray
XM56_RS11455	COG0513	Belongs to the DEAD box helicase family
XM56_RS11460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
XM56_RS11465	COG3140	Belongs to the UPF0181 family
XM56_RS11475	COG0494	nUDIX hydrolase
XM56_RS11480	COG1760	l-serine dehydratase
XM56_RS11490	COG1253	flavin adenine dinucleotide binding
XM56_RS11495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS11495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS11500	COG3715	PTS system
XM56_RS11505	COG3716	PTS system mannose fructose sorbose family IID component
XM56_RS11510	COG4811	Protein of unknown function (DUF986)
XM56_RS11515	COG1971	Probably functions as a manganese efflux pump
XM56_RS11525	COG5001	Diguanylate cyclase
XM56_RS11525	COG5002	protein histidine kinase activity
XM56_RS11525	COG3447	MASE1 domain protein
XM56_RS11535	COG2226	methyltransferase
XM56_RS11540	COG0768	penicillin binding
XM56_RS11545	COG1496	oxidoreductase activity
XM56_RS11565	COG1113	amino acid transport
XM56_RS11595	COG2207	Transcriptional regulator
XM56_RS11615	COG1132	(ABC) transporter
XM56_RS11635	COG2203	Gaf domain
XM56_RS11635	COG3706	GGDEF domain
XM56_RS11635	COG4251	negative regulation of phosphorylation
XM56_RS11635	COG5001	Diguanylate cyclase
XM56_RS11650	COG3755	Protein conserved in bacteria
XM56_RS11675	COG1733	regulation of RNA biosynthetic process
XM56_RS11680	COG0702	epimerase
XM56_RS11705	COG0840	transmembrane signaling receptor activity
XM56_RS11740	COG0538	isocitrate dehydrogenase activity
XM56_RS11770	COG0538	isocitrate dehydrogenase activity
XM56_RS11775	COG1187	pseudouridine synthase activity
XM56_RS11785	COG0482	sulfurtransferase activity
XM56_RS11790	COG2915	High frequency lysogenization protein hflD homolog
XM56_RS11795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
XM56_RS11805	COG0745	RESPONSE REGULATOR receiver
XM56_RS11815	COG2850	peptidyl-arginine hydroxylation
XM56_RS11830	COG1940	carbohydrate kinase activity
XM56_RS11835	COG4591	ABC-type transport system involved in lipoprotein release permease component
XM56_RS11845	COG4591	ABC-type transport system involved in lipoprotein release permease component
XM56_RS11850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
XM56_RS11855	COG3134	Outer membrane lipoprotein
XM56_RS11860	COG1252	NADH dehydrogenase
XM56_RS11865	COG3150	esterase
XM56_RS11870	COG1472	Belongs to the glycosyl hydrolase 3 family
XM56_RS11880	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
XM56_RS11885	COG5633	Lipoprotein
XM56_RS11890	COG0537	adenosine 5'-monophosphoramidase activity
XM56_RS11895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
XM56_RS11905	COG0641	radical SAM
XM56_RS11925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS11925	COG1263	PTS System
XM56_RS11930	COG0084	hydrolase, TatD family'
XM56_RS11935	COG0470	DNA polymerase III
XM56_RS11940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
XM56_RS11945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
XM56_RS11950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XM56_RS11955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XM56_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS11970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
XM56_RS11975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
XM56_RS11980	COG0416	fatty acid biosynthetic process
XM56_RS11985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
XM56_RS11990	COG1399	metal-binding, possibly nucleic acid-binding protein
XM56_RS11995	COG0424	maF-like protein
XM56_RS12000	COG0564	pseudouridine synthase activity
XM56_RS12005	COG1530	ribonuclease E activity
XM56_RS12010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
XM56_RS12015	COG0418	dihydroorotase activity
XM56_RS12040	COG0628	permease
XM56_RS12045	COG1054	Belongs to the UPF0176 family
XM56_RS12075	COG1560	Kdo2-lipid A biosynthetic process
XM56_RS12085	COG2259	Doxx family
XM56_RS12110	COG5645	(Lipo)protein
XM56_RS12115	COG2943	transferase activity, transferring hexosyl groups
XM56_RS12120	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
XM56_RS12140	COG3263	regulation of cellular component size
XM56_RS12150	COG3916	Acyl-homoserine-lactone synthase
XM56_RS12155	COG2771	luxR family
XM56_RS12160	COG4235	cytochrome complex assembly
XM56_RS12165	COG3088	subunit of a heme lyase
XM56_RS12170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XM56_RS12175	COG1138	Cytochrome C-type biogenesis protein
XM56_RS12180	COG3301	Polysulphide reductase, NrfD
XM56_RS12185	COG0437	4 iron, 4 sulfur cluster binding
XM56_RS12190	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
XM56_RS12205	COG2920	part of a sulfur-relay system
XM56_RS12210	COG1254	Belongs to the acylphosphatase family
XM56_RS12225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XM56_RS12230	COG3785	DNA binding
XM56_RS12235	COG1832	CoA-binding protein
XM56_RS12245	COG1803	Methylglyoxal synthase
XM56_RS12250	COG0210	DNA helicase
XM56_RS12255	COG3304	Inner membrane component domain
XM56_RS12260	COG1289	transmembrane transporter activity
XM56_RS12265	COG3070	regulator of competence-specific genes
XM56_RS12270	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
XM56_RS12280	COG3120	sequence-specific DNA binding
XM56_RS12285	COG1067	ATP-dependent peptidase activity
XM56_RS12290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XM56_RS12305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XM56_RS12310	COG3009	Protein conserved in bacteria
XM56_RS12315	COG3008	intermembrane lipid transfer
XM56_RS12315	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
XM56_RS12320	COG2995	paraquat-inducible protein a
XM56_RS12325	COG0488	(ABC) transporter
XM56_RS12330	COG0116	Belongs to the methyltransferase superfamily
XM56_RS12330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
XM56_RS12335	COG3217	Mosc domain protein beta barrel domain protein
XM56_RS12335	COG0633	Ferredoxin
XM56_RS12345	COG0167	dihydroorotate dehydrogenase activity
XM56_RS12350	COG0308	aminopeptidase N
XM56_RS12355	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
XM56_RS12360	COG0017	Asparaginyl-tRNA synthetase
XM56_RS12370	COG1448	Aminotransferase
XM56_RS12385	COG2200	EAL domain
XM56_RS12390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XM56_RS12395	COG3108	Peptidase M15
XM56_RS12400	COG2989	Protein conserved in bacteria
XM56_RS12405	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
XM56_RS12415	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
XM56_RS12420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XM56_RS12425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
XM56_RS12430	COG3173	Aminoglycoside phosphotransferase
XM56_RS12435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
XM56_RS12440	COG2835	tetraacyldisaccharide 4'-kinase activity
XM56_RS12445	COG1278	Cold shock
XM56_RS12455	COG5383	Protein conserved in bacteria
XM56_RS12460	COG1663	tetraacyldisaccharide 4'-kinase activity
XM56_RS12470	COG0658	competence protein
XM56_RS12470	COG2333	competence protein COMEC
XM56_RS12475	COG0776	regulation of translation
XM56_RS12480	COG0539	negative regulation of cytoplasmic translation
XM56_RS12485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
XM56_RS12490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
XM56_RS12495	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
XM56_RS12500	COG2323	membrane
XM56_RS12505	COG0252	asparaginase activity
XM56_RS12510	COG1944	ATP diphosphatase activity
XM56_RS12515	COG2116	formate transmembrane transporter activity
XM56_RS12520	COG1882	Formate acetyltransferase
XM56_RS12525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
XM56_RS12530	COG2814	Major facilitator Superfamily
XM56_RS12540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
XM56_RS12545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
XM56_RS12550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
XM56_RS12555	COG1674	ftsk spoiiie
XM56_RS12555	COG3107	peptidoglycan biosynthetic process
XM56_RS12560	COG1522	sequence-specific DNA binding
XM56_RS12565	COG0492	ferredoxin-NADP+ reductase activity
XM56_RS12575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
XM56_RS12580	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
XM56_RS12585	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
XM56_RS12590	COG0542	response to heat
XM56_RS12595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
XM56_RS12600	COG1278	Cold shock
XM56_RS12610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS12615	COG2990	Protein conserved in bacteria
XM56_RS12620	COG3593	DNA synthesis involved in DNA repair
XM56_RS12625	COG2431	L-lysine efflux transmembrane transporter activity
XM56_RS12630	COG1151	hydroxylamine reductase activity
XM56_RS12635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XM56_RS12640	COG0028	Belongs to the TPP enzyme family
XM56_RS12650	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
XM56_RS12655	COG0702	epimerase
XM56_RS12660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XM56_RS12670	COG1126	abc transporter atp-binding protein
XM56_RS12675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS12680	COG4215	(ABC) transporter
XM56_RS12685	COG4160	amino acid transport
XM56_RS12690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS12695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XM56_RS12705	COG1177	transmembrane transport
XM56_RS12710	COG1176	ABC-type spermidine putrescine transport system, permease component I
XM56_RS12715	COG3842	ATPase activity
XM56_RS12720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
XM56_RS12740	COG0569	domain protein
XM56_RS12740	COG2985	domain, Protein
XM56_RS12750	COG0671	phosphoesterase, PA-phosphatase related
XM56_RS12755	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
XM56_RS12760	COG1349	DNA-binding transcription factor activity
XM56_RS12765	COG0814	amino acid
XM56_RS12770	COG1760	l-serine dehydratase
XM56_RS12780	COG1686	Belongs to the peptidase S11 family
XM56_RS12790	COG0626	cystathionine gamma-synthase activity
XM56_RS12795	COG2011	ABC-type metal ion transport system permease component
XM56_RS12820	COG0625	glutathione transferase activity
XM56_RS12825	COG4771	TonB-dependent receptor
XM56_RS12835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XM56_RS12840	COG0833	amino acid
XM56_RS12845	COG0583	DNA-binding transcription factor activity
XM56_RS12860	COG2855	membrane
XM56_RS12870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
XM56_RS12895	COG3710	Transcriptional regulator
XM56_RS12900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XM56_RS12900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
XM56_RS12900	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
XM56_RS12905	COG1105	Belongs to the carbohydrate kinase PfkB family
XM56_RS12920	COG3005	denitrification pathway
XM56_RS12925	COG0243	molybdopterin cofactor binding
XM56_RS12940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XM56_RS12945	COG1312	Catalyzes the dehydration of D-mannonate
XM56_RS12955	COG0246	Mannitol dehydrogenase
XM56_RS12960	COG2186	Transcriptional regulator
XM56_RS12970	COG0523	cobalamin synthesis protein
XM56_RS12975	COG0671	phosphoesterase, PA-phosphatase related
XM56_RS12980	COG0791	NLP P60 protein
XM56_RS12990	COG2200	EAL domain
XM56_RS12995	COG4166	transmembrane transport
XM56_RS13000	COG4174	ABC transporter (Permease)
XM56_RS13005	COG4239	(ABC) transporter, permease
XM56_RS13010	COG4172	Belongs to the ABC transporter superfamily
XM56_RS13020	COG2814	Major facilitator Superfamily
XM56_RS13025	COG1187	pseudouridine synthase activity
XM56_RS13030	COG1061	Type III restriction enzyme res subunit
XM56_RS13035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
XM56_RS13040	COG3081	Nucleoid-associated protein
XM56_RS13045	COG3082	Protein of unknown function (DUF1414)
XM56_RS13070	COG3328	transposase activity
XM56_RS13085	COG2801	Transposase and inactivated derivatives
XM56_RS13105	COG2723	6-phospho-beta-galactosidase activity
XM56_RS13110	COG1263	PTS System
XM56_RS13110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS13110	COG2190	(PTS) system
XM56_RS13115	COG1737	Transcriptional regulator
XM56_RS13170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
XM56_RS13185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
XM56_RS13200	COG2223	nitrite transmembrane transporter activity
XM56_RS13205	COG2198	Histidine kinase
XM56_RS13205	COG0642	Histidine kinase
XM56_RS13210	COG2197	response regulator
XM56_RS13215	COG0784	Response regulator, receiver
XM56_RS13215	COG2205	protein histidine kinase activity
XM56_RS13230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
XM56_RS13235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XM56_RS13245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XM56_RS13250	COG4574	serine-type endopeptidase inhibitor activity
XM56_RS13270	COG0814	amino acid
XM56_RS13290	COG1441	menaquinone biosynthetic process
XM56_RS13295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
XM56_RS13300	COG0596	Alpha beta hydrolase
XM56_RS13305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
XM56_RS13310	COG1169	isochorismate synthase
XM56_RS13315	COG3328	transposase activity
XM56_RS13320	COG4575	ribosome binding
XM56_RS13330	COG4702	Belongs to the UPF0303 family
XM56_RS13340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
XM56_RS13350	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS13355	COG3265	gluconokinase activity
XM56_RS13375	COG1007	ATP synthesis coupled electron transport
XM56_RS13380	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS13385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
XM56_RS13390	COG0713	ATP synthesis coupled electron transport
XM56_RS13395	COG0839	Belongs to the complex I subunit 6 family
XM56_RS13400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS13405	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
XM56_RS13410	COG1034	ATP synthesis coupled electron transport
XM56_RS13425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS13425	COG0649	NAD binding
XM56_RS13430	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS13435	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
XM56_RS13440	COG0583	DNA-binding transcription factor activity
XM56_RS13445	COG0436	Aminotransferase
XM56_RS13450	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
XM56_RS13455	COG0471	metal ion transport
XM56_RS13455	COG0490	domain, Protein
XM56_RS13465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XM56_RS13470	COG3013	Belongs to the UPF0304 family
XM56_RS13475	COG3092	negative regulation of chromosome organization
XM56_RS13485	COG0280	phosphate acetyltransferase
XM56_RS13485	COG0857	belongs to the CobB CobQ family
XM56_RS13490	COG1609	Transcriptional regulator
XM56_RS13495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS13505	COG3037	sugar-specific permease SgaT UlaA
XM56_RS13515	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
XM56_RS13520	COG0622	Phosphoesterase
XM56_RS13530	COG1090	epimerase
XM56_RS13540	COG4598	ABC transporter
XM56_RS13545	COG4160	amino acid transport
XM56_RS13550	COG4215	(ABC) transporter
XM56_RS13555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS13560	COG0163	prenyltransferase activity
XM56_RS13565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
XM56_RS13570	COG1286	toxin biosynthetic process
XM56_RS13575	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
XM56_RS13580	COG0285	dihydrofolate synthase activity
XM56_RS13585	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
XM56_RS13590	COG0586	Pfam SNARE associated Golgi protein
XM56_RS13600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
XM56_RS13605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
XM56_RS13615	COG0697	spore germination
XM56_RS13620	COG0697	spore germination
XM56_RS13625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XM56_RS13630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XM56_RS13655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
XM56_RS13665	COG1609	Transcriptional regulator
XM56_RS13675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XM56_RS13680	COG2723	6-phospho-beta-galactosidase activity
XM56_RS13685	COG1447	Phosphotransferase system cellobiose-specific component IIA
XM56_RS13695	COG1794	racemase activity, acting on amino acids and derivatives
XM56_RS13700	COG3706	GGDEF domain
XM56_RS13705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
XM56_RS13710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
XM56_RS13710	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
XM56_RS13720	COG3101	peptidyl-lysine hydroxylation
XM56_RS13725	COG0730	response to heat
XM56_RS13730	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
XM56_RS13735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
XM56_RS13740	COG2890	protein-(glutamine-N5) methyltransferase activity
XM56_RS13745	COG2840	Smr protein MutS2
XM56_RS13750	COG2062	phosphohistidine phosphatase, SixA
XM56_RS13755	COG1024	Enoyl-CoA hydratase
XM56_RS13755	COG1250	3-hydroxyacyl-CoA dehydrogenase
XM56_RS13760	COG0183	Belongs to the thiolase family
XM56_RS13765	COG3691	Protein conserved in bacteria
XM56_RS13780	COG3088	subunit of a heme lyase
XM56_RS13780	COG4235	cytochrome complex assembly
XM56_RS13790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
XM56_RS13795	COG1138	Cytochrome C-type biogenesis protein
XM56_RS13800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
XM56_RS13805	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XM56_RS13810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XM56_RS13815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
XM56_RS13830	COG2116	formate transmembrane transporter activity
XM56_RS13840	COG0582	viral genome integration into host DNA
XM56_RS13905	COG2824	Alkylphosphonate utilization operon protein PhnA
XM56_RS13910	COG1695	Transcriptional regulator
XM56_RS13920	COG2723	6-phospho-beta-galactosidase activity
XM56_RS13925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
XM56_RS13925	COG1263	PTS System
XM56_RS13930	COG1609	Transcriptional regulator
XM56_RS13935	COG2353	YceI-like domain
XM56_RS13940	COG3038	cytochrome b561
XM56_RS13945	COG0657	acetylesterase activity
XM56_RS13945	COG2755	lipolytic protein G-D-S-L family
XM56_RS13965	COG1127	ABC transporter
XM56_RS13970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
XM56_RS14000	COG0531	amino acid
XM56_RS14005	COG2951	lytic endotransglycosylase activity
XM56_RS14025	COG1280	lysine exporter protein (LysE YggA)
XM56_RS14035	COG1598	PFAM Uncharacterised protein family UPF0150
XM56_RS14040	COG3038	cytochrome b561
XM56_RS14045	COG0436	Aminotransferase
XM56_RS14060	COG3275	phosphorelay sensor kinase activity
XM56_RS14065	COG3279	Response regulator of the LytR AlgR family
XM56_RS14070	COG2223	nitrite transmembrane transporter activity
XM56_RS14080	COG0837	glucose binding
XM56_RS14095	COG3961	Belongs to the TPP enzyme family
XM56_RS14100	COG0667	Aldo Keto reductase
XM56_RS14110	COG1914	H( )-stimulated, divalent metal cation uptake system
XM56_RS14115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XM56_RS14130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
XM56_RS14160	COG3530	Putative quorum-sensing-regulated virulence factor
XM56_RS14165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XM56_RS14185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS14190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XM56_RS14200	COG2205	protein histidine kinase activity
XM56_RS14205	COG0745	RESPONSE REGULATOR receiver
XM56_RS14210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS14230	COG4208	sulfate ABC transporter
XM56_RS14235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
XM56_RS14240	COG4150	thiosulfate binding
XM56_RS14250	COG1737	Transcriptional regulator
XM56_RS14255	COG2731	YhcH YjgK YiaL family protein
XM56_RS14270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XM56_RS14280	COG2837	iron assimilation
XM56_RS14290	COG3111	PFAM Bacterial OB fold (BOF) protein
XM56_RS14295	COG0456	acetyltransferase
XM56_RS14300	COG0408	coproporphyrinogen oxidase activity
XM56_RS14305	COG1671	Belongs to the UPF0178 family
XM56_RS14320	COG0280	phosphate acetyltransferase
XM56_RS14320	COG0281	malic enzyme
XM56_RS14325	COG0494	nUDIX hydrolase
XM56_RS14330	COG3005	denitrification pathway
XM56_RS14335	COG3043	anaerobic respiration
XM56_RS14340	COG0243	molybdopterin cofactor binding
XM56_RS14345	COG3062	negative regulation of establishment of protein localization
XM56_RS14355	COG2197	response regulator
XM56_RS14365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XM56_RS14380	COG1393	Belongs to the ArsC family
XM56_RS14385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
XM56_RS14390	COG1876	peptidase activity
XM56_RS14430	COG0400	carboxylic ester hydrolase activity
XM56_RS14445	COG1444	tRNA N-acetyltransferase activity
XM56_RS14450	COG2707	UPF0756 membrane protein
XM56_RS14455	COG2321	neutral zinc metallopeptidase
XM56_RS14460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
XM56_RS14465	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
XM56_RS14470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
XM56_RS14475	COG2716	regulation of RNA biosynthetic process
XM56_RS14480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
XM56_RS14485	COG0628	permease
XM56_RS14490	COG4783	chaperone-mediated protein folding
XM56_RS14495	COG1393	Belongs to the ArsC family
XM56_RS14500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
XM56_RS14505	COG2233	PERMEase
XM56_RS14510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
XM56_RS14515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
XM56_RS14520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
XM56_RS14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
XM56_RS14540	COG0581	inorganic phosphate transmembrane transporter activity
XM56_RS14545	COG0573	inorganic phosphate transmembrane transporter activity
XM56_RS14550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
XM56_RS14565	COG2239	Acts as a magnesium transporter
XM56_RS14570	COG3447	MASE1 domain protein
XM56_RS14570	COG5002	protein histidine kinase activity
XM56_RS14570	COG5001	Diguanylate cyclase
XM56_RS14575	COG0443	Heat shock 70 kDa protein
XM56_RS14580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS14590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XM56_RS14595	COG0477	Major facilitator Superfamily
XM56_RS14600	COG2205	protein histidine kinase activity
XM56_RS14605	COG0745	RESPONSE REGULATOR receiver
XM56_RS14610	COG3422	double-strand break repair
XM56_RS14615	COG0826	peptidase U32
XM56_RS14620	COG1597	lipid kinase activity
XM56_RS14625	COG3730	PTS system glucitol sorbitol-specific
XM56_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS14645	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS14650	COG1349	DNA-binding transcription factor activity
XM56_RS14670	COG0351	phosphomethylpyrimidine kinase
XM56_RS14705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
XM56_RS14705	COG0519	Catalyzes the synthesis of GMP from XMP
XM56_RS14710	COG0517	IMP dehydrogenase activity
XM56_RS14710	COG0516	GMP reductase activity
XM56_RS14715	COG1570	exodeoxyribonuclease VII activity
XM56_RS14720	COG1645	bacterial-type flagellum-dependent swarming motility
XM56_RS14735	COG1160	GTP binding
XM56_RS14745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XM56_RS14750	COG2976	Protein conserved in bacteria
XM56_RS14755	COG0124	histidyl-tRNA synthetase
XM56_RS14760	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
XM56_RS14765	COG1426	Protein conserved in bacteria
XM56_RS14775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
XM56_RS14790	COG4953	penicillin-binding protein 1C
XM56_RS14795	COG2373	Large extracellular alpha-helical protein
XM56_RS14800	COG3468	outer membrane autotransporter barrel domain protein
XM56_RS14815	COG2975	iron-sulfur cluster assembly
XM56_RS14820	COG0633	Ferredoxin
XM56_RS14825	COG0443	Heat shock 70 kDa protein
XM56_RS14830	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XM56_RS14835	COG0316	Belongs to the HesB IscA family
XM56_RS14840	COG0822	iron-sulfur transferase activity
XM56_RS14850	COG1959	2 iron, 2 sulfur cluster binding
XM56_RS14855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
XM56_RS14865	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
XM56_RS14870	COG3683	transport system, periplasmic component
XM56_RS14875	COG3711	transcriptional antiterminator
XM56_RS14880	COG2814	Major facilitator Superfamily
XM56_RS14885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
XM56_RS14890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
XM56_RS14890	COG1017	nitric oxide dioxygenase activity
XM56_RS14895	COG2188	Transcriptional regulator
XM56_RS14905	COG3457	Alanine racemase
XM56_RS14910	COG1735	metal-dependent hydrolase with the TIM-barrel fold
XM56_RS14925	COG0347	Belongs to the P(II) protein family
XM56_RS14930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
XM56_RS14930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
XM56_RS14935	COG2204	response regulator
XM56_RS14940	COG3170	Tfp pilus assembly protein FimV
XM56_RS14945	COG2205	protein histidine kinase activity
XM56_RS14960	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
XM56_RS14975	COG0560	Phosphoserine phosphatase
XM56_RS14985	COG1737	Transcriptional regulator
XM56_RS14990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
XM56_RS14995	COG2610	gluconate transmembrane transporter activity
XM56_RS15000	COG0736	holo-[acyl-carrier-protein] synthase activity
XM56_RS15005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
XM56_RS15010	COG1381	Involved in DNA repair and RecF pathway recombination
XM56_RS15015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
XM56_RS15020	COG0571	ribonuclease III activity
XM56_RS15030	COG0481	GTPase activity
XM56_RS15040	COG3086	response to oxidative stress
XM56_RS15050	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
XM56_RS15060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
XM56_RS15065	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
XM56_RS15070	COG0513	Belongs to the DEAD box helicase family
XM56_RS15100	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
XM56_RS15105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
XM56_RS15110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
XM56_RS15115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
XM56_RS15120	COG0497	DNA recombination
XM56_RS15125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
XM56_RS15135	COG2867	negative regulation of translational initiation
XM56_RS15140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
XM56_RS15145	COG0582	viral genome integration into host DNA
XM56_RS15185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XM56_RS15205	COG3394	polysaccharide catabolic process
XM56_RS15210	COG2169	Transcriptional regulator
XM56_RS15210	COG1917	Cupin 2, conserved barrel domain protein
XM56_RS15215	COG1447	Phosphotransferase system cellobiose-specific component IIA
XM56_RS15220	COG2723	6-phospho-beta-galactosidase activity
XM56_RS15225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XM56_RS15230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
XM56_RS15235	COG2133	pyrroloquinoline quinone binding
XM56_RS15260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
XM56_RS15270	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
XM56_RS15275	COG4413	Urea transporter
XM56_RS15280	COG0829	nickel cation binding
XM56_RS15285	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
XM56_RS15290	COG0830	nickel cation binding
XM56_RS15295	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
XM56_RS15300	COG0804	urea catabolic process
XM56_RS15305	COG0832	Belongs to the urease beta subunit family
XM56_RS15310	COG0831	urea catabolic process
XM56_RS15315	COG1124	(ABC) transporter
XM56_RS15325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XM56_RS15365	COG1278	Cold shock
XM56_RS15390	COG2207	Transcriptional regulator
XM56_RS15410	COG4575	ribosome binding
XM56_RS15420	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
XM56_RS15430	COG1780	Probably involved in ribonucleotide reductase function
XM56_RS15440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
XM56_RS15450	COG4176	ABC-type proline glycine betaine transport system permease component
XM56_RS15455	COG2113	Glycine betaine
XM56_RS15470	COG0328	RNA-DNA hybrid ribonuclease activity
XM56_RS15475	COG2226	methyltransferase
XM56_RS15480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
XM56_RS15485	COG1388	LysM domain
XM56_RS15485	COG0741	lytic transglycosylase activity
XM56_RS15495	COG3021	interspecies interaction between organisms
XM56_RS15500	COG2814	Major facilitator Superfamily
XM56_RS15505	COG0583	DNA-binding transcription factor activity
XM56_RS15510	COG0656	L-ascorbic acid biosynthetic process
XM56_RS15520	COG3328	transposase activity
XM56_RS15550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
XM56_RS15560	COG2011	ABC-type metal ion transport system permease component
XM56_RS15565	COG1464	Belongs to the NlpA lipoprotein family
XM56_RS15575	COG1720	tRNA m6t6A37 methyltransferase activity
XM56_RS15580	COG0442	prolyl-tRNA aminoacylation
XM56_RS15585	COG3015	lipoprotein NlpE involved in copper resistance
XM56_RS15595	COG4681	YaeQ
XM56_RS15605	COG4568	rho-dependent transcription termination
XM56_RS15620	COG0346	lactoylglutathione lyase activity
XM56_RS15625	COG1982	Orn Lys Arg decarboxylase major
XM56_RS15630	COG0825	malonyl-CoA metabolic process
XM56_RS15640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
XM56_RS15650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XM56_RS15655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
XM56_RS15660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
XM56_RS15665	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
XM56_RS15675	COG0750	zinc metalloprotease
XM56_RS15680	COG0575	Belongs to the CDS family
XM56_RS15690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
XM56_RS15695	COG0233	cytoplasmic translational termination
XM56_RS15700	COG0528	UMP kinase activity
XM56_RS15705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
XM56_RS15710	COG0052	Belongs to the universal ribosomal protein uS2 family
XM56_RS15720	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
XM56_RS15725	COG2171	N-acyltransferase activity
XM56_RS15740	COG0564	pseudouridine synthase activity
XM56_RS15745	COG3098	single-species biofilm formation
XM56_RS15755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XM56_RS15755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
XM56_RS15760	COG1611	Belongs to the LOG family
XM56_RS15765	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XM56_RS15775	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
XM56_RS15780	COG2363	Small membrane protein
XM56_RS15785	COG0583	DNA-binding transcription factor activity
XM56_RS15795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
XM56_RS15800	COG2166	iron-sulfur cluster assembly
XM56_RS15805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
XM56_RS15810	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
XM56_RS15820	COG0860	N-Acetylmuramoyl-L-alanine amidase
XM56_RS15825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XM56_RS15825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
XM56_RS15835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
XM56_RS15840	COG1074	ATP-dependent DNA helicase activity
XM56_RS15845	COG1025	Belongs to the peptidase M16 family
XM56_RS15850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
XM56_RS15870	COG2165	general secretion pathway protein
XM56_RS15875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
XM56_RS15880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
XM56_RS15890	COG1051	belongs to the nudix hydrolase family
XM56_RS15900	COG3066	DNA modification
XM56_RS15905	COG0861	Integral membrane protein TerC family
XM56_RS15910	COG0667	Aldo Keto reductase
XM56_RS15915	COG0477	Major facilitator Superfamily
XM56_RS15920	COG0318	PFAM AMP-dependent synthetase and ligase
XM56_RS15920	COG0204	Acyl-transferase
XM56_RS15935	COG1609	Transcriptional regulator
XM56_RS15945	COG0583	DNA-binding transcription factor activity
XM56_RS15950	COG2814	Major facilitator Superfamily
XM56_RS15990	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
XM56_RS16020	COG2165	general secretion pathway protein
XM56_RS16030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XM56_RS16050	COG0288	reversible hydration of carbon dioxide
XM56_RS16055	COG1733	regulation of RNA biosynthetic process
XM56_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS16070	COG0484	heat shock protein binding
XM56_RS16085	COG2271	Major facilitator Superfamily
XM56_RS16100	COG1522	sequence-specific DNA binding
XM56_RS16110	COG3706	GGDEF domain
XM56_RS16115	COG4319	ketosteroid isomerase
XM56_RS16130	COG3328	transposase activity
XM56_RS16135	COG2944	sequence-specific DNA binding
XM56_RS16205	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
XM56_RS16210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
XM56_RS16215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
XM56_RS16220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XM56_RS16225	COG4974	Belongs to the 'phage' integrase family
XM56_RS16230	COG0716	FMN binding
XM56_RS16235	COG4452	Inner membrane protein CreD
XM56_RS16240	COG2205	protein histidine kinase activity
XM56_RS16245	COG0745	RESPONSE REGULATOR receiver
XM56_RS16260	COG0354	folic acid binding
XM56_RS16270	COG1272	protein, Hemolysin III
XM56_RS16280	COG1028	Short-chain dehydrogenase reductase Sdr
XM56_RS16290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XM56_RS16290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
XM56_RS16295	COG0509	glycine decarboxylation via glycine cleavage system
XM56_RS16300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
XM56_RS16305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XM56_RS16310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
XM56_RS16315	COG0006	proline dipeptidase activity
XM56_RS16320	COG3079	Belongs to the UPF0149 family
XM56_RS16325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
XM56_RS16330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
XM56_RS16335	COG0148	phosphopyruvate hydratase activity
XM56_RS16340	COG0504	CTP synthase activity
XM56_RS16345	COG3956	TIGRFAM MazG family protein
XM56_RS16350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XM56_RS16355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XM56_RS16360	COG2205	protein histidine kinase activity
XM56_RS16360	COG3437	response regulator, receiver
XM56_RS16360	COG3850	Histidine kinase
XM56_RS16360	COG4999	Histidine kinase
XM56_RS16365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
XM56_RS16370	COG0232	Belongs to the dGTPase family. Type 2 subfamily
XM56_RS16375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
XM56_RS16385	COG2860	membrane
XM56_RS16390	COG0316	Belongs to the HesB IscA family
XM56_RS16400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
XM56_RS16405	COG2223	nitrite transmembrane transporter activity
XM56_RS16410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XM56_RS16415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
XM56_RS16420	COG1120	ATPase activity
XM56_RS16425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
XM56_RS16430	COG1643	Atp-dependent helicase
XM56_RS16435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
XM56_RS16440	COG1489	DNA binding
XM56_RS16460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
XM56_RS16465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
XM56_RS16470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
XM56_RS16475	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
XM56_RS16480	COG0726	polysaccharide deacetylase
XM56_RS16485	COG0842	Transport permease protein
XM56_RS16490	COG1131	(ABC) transporter
XM56_RS16495	COG0288	reversible hydration of carbon dioxide
XM56_RS16500	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
XM56_RS16505	COG2132	Multicopper oxidase
XM56_RS16515	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
XM56_RS16520	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
XM56_RS16535	COG3112	Uncharacterised protein family (UPF0231)
XM56_RS16550	COG4977	sequence-specific DNA binding
XM56_RS16560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XM56_RS16565	COG0508	dehydrogenase complex catalyzes the overall conversion of
XM56_RS16570	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
XM56_RS16575	COG2186	Transcriptional regulator
XM56_RS16580	COG1113	amino acid transport
XM56_RS16585	COG3725	Membrane protein required for beta-lactamase induction
XM56_RS16600	COG4969	Belongs to the N-Me-Phe pilin family
XM56_RS16605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
XM56_RS16610	COG1459	type II secretion system
XM56_RS16615	COG0516	GMP reductase activity
XM56_RS16630	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
XM56_RS16635	COG0494	nUDIX hydrolase
XM56_RS16640	COG0653	protein targeting
XM56_RS16660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
XM56_RS16665	COG0849	cell division
XM56_RS16670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
XM56_RS16680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XM56_RS16685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
XM56_RS16690	COG0772	Belongs to the SEDS family
XM56_RS16700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XM56_RS16705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
XM56_RS16710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
XM56_RS16715	COG0768	penicillin binding
XM56_RS16720	COG3116	cell division
XM56_RS16725	COG0275	rRNA processing
XM56_RS16730	COG2001	Belongs to the MraZ family
XM56_RS16755	COG0028	Belongs to the TPP enzyme family
XM56_RS16760	COG1022	Amp-dependent synthetase and ligase
XM56_RS16770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
XM56_RS16775	COG0473	3-isopropylmalate dehydrogenase activity
XM56_RS16780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
XM56_RS16795	COG3033	Beta-eliminating lyase
XM56_RS16800	COG0814	amino acid
XM56_RS16810	COG2814	Major facilitator Superfamily
XM56_RS16815	COG1882	Formate acetyltransferase
XM56_RS16820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
XM56_RS16825	COG4533	DNA binding
XM56_RS16840	COG4143	(ABC) transporter
XM56_RS16845	COG1178	ABC-type Fe3 transport system permease component
XM56_RS16855	COG0586	Pfam SNARE associated Golgi protein
XM56_RS16860	COG0417	DNA replication proofreading
XM56_RS16865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
XM56_RS16870	COG1470	cell adhesion involved in biofilm formation
XM56_RS16870	COG1388	LysM domain
XM56_RS16875	COG0564	pseudouridine synthase activity
XM56_RS16880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
XM56_RS16885	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
XM56_RS16900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
XM56_RS16905	COG2967	ApaG domain
XM56_RS16910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
XM56_RS16915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
XM56_RS16920	COG3610	response to peptide
XM56_RS16925	COG2966	Psort location CytoplasmicMembrane, score
XM56_RS16930	COG1280	lysine exporter protein (LysE YggA)
XM56_RS16935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
XM56_RS16945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
XM56_RS16950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
XM56_RS16955	COG1047	Peptidyl-prolyl cis-trans
XM56_RS16960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
XM56_RS16965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
XM56_RS16970	COG0196	riboflavin kinase activity
XM56_RS16980	COG0268	Binds directly to 16S ribosomal RNA
XM56_RS16985	COG0583	DNA-binding transcription factor activity
XM56_RS16990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
XM56_RS16995	COG0484	heat shock protein binding
XM56_RS17000	COG0443	Heat shock 70 kDa protein
XM56_RS17005	COG1584	GPR1 FUN34 yaaH family protein
XM56_RS17020	COG0521	Mo-molybdopterin cofactor biosynthetic process
XM56_RS17025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
XM56_RS17030	COG3022	response to hydroperoxide
XM56_RS17045	COG0083	homoserine kinase activity
XM56_RS17060	COG0745	RESPONSE REGULATOR receiver
XM56_RS17065	COG3045	CreA protein
XM56_RS17070	COG2207	Transcriptional regulator
XM56_RS17070	COG3708	Transcriptional regulator
XM56_RS17075	COG0406	alpha-ribazole phosphatase activity
XM56_RS17080	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
XM56_RS17085	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
XM56_RS17090	COG0741	lytic transglycosylase activity
XM56_RS17095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
XM56_RS17105	COG2199	diguanylate cyclase activity
XM56_RS17110	COG2885	chlorophyll binding
XM56_RS17115	COG0488	(ABC) transporter
XM56_RS17130	COG0604	alcohol dehydrogenase
XM56_RS17145	COG0560	Phosphoserine phosphatase
XM56_RS17150	COG3726	membrane protein affecting hemolysin expression
XM56_RS17155	COG0813	purine-nucleoside phosphorylase activity
XM56_RS17160	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
XM56_RS17165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
XM56_RS17175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XM56_RS17180	COG0084	hydrolase, TatD family'
XM56_RS17185	COG4667	esterase of the alpha-beta hydrolase superfamily
XM56_RS17190	COG2823	Periplasmic or secreted lipoprotein
XM56_RS17195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
XM56_RS17200	COG0456	acetyltransferase
XM56_RS17205	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
XM56_RS17210	COG2813	Specifically methylates the guanine in position
XM56_RS17215	COG0667	Aldo Keto reductase
XM56_RS17220	COG0583	DNA-binding transcription factor activity
XM56_RS17240	COG4772	TonB-dependent receptor
XM56_RS17275	COG3284	Transcriptional regulator
XM56_RS17305	COG2192	nodulation
XM56_RS17315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
XM56_RS17315	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
XM56_RS17315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
XM56_RS17320	COG1461	Dihydroxyacetone kinase
XM56_RS17325	COG2376	Dihydroxyacetone kinase
XM56_RS17335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
XM56_RS17340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
XM56_RS17345	COG2235	arginine
XM56_RS17360	COG0859	PFAM glycosyl transferase family 9
XM56_RS17365	COG1070	Carbohydrate kinase
XM56_RS17370	COG2390	Transcriptional regulator
XM56_RS17375	COG1129	ABC transporter
XM56_RS17380	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS17385	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS17390	COG1879	ABC-type sugar transport system periplasmic component
XM56_RS17395	COG1830	Aldolase
XM56_RS17400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
XM56_RS17415	COG3328	transposase activity
XM56_RS17450	COG0454	-acetyltransferase
XM56_RS17455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
XM56_RS17455	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
XM56_RS17510	COG0795	lipopolysaccharide-transporting ATPase activity
XM56_RS17515	COG0795	lipopolysaccharide-transporting ATPase activity
XM56_RS17520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
XM56_RS17525	COG2927	DNA polymerase III (CHI subunit)
XM56_RS17545	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
XM56_RS17555	COG2731	YhcH YjgK YiaL family protein
XM56_RS17565	COG0601	transmembrane transport
XM56_RS17570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
XM56_RS17575	COG0444	Belongs to the ABC transporter superfamily
XM56_RS17580	COG4608	Belongs to the ABC transporter superfamily
XM56_RS17610	COG2188	Transcriptional regulator
XM56_RS17615	COG3624	Phosphonate C-P lyase system protein PhnG
XM56_RS17620	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
XM56_RS17625	COG3626	phosphonate metabolism
XM56_RS17630	COG3627	carbon phosphorus lyase activity
XM56_RS17635	COG4107	phosphonate C-P lyase system protein PhnK
XM56_RS17640	COG4778	phosphonate C-P lyase system protein PhnL
XM56_RS17645	COG3454	Phosphonate metabolism
XM56_RS17650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
XM56_RS17655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
XM56_RS17660	COG0702	epimerase
XM56_RS17675	COG3787	Belongs to the UPF0306 family
XM56_RS17685	COG3842	ATPase activity
XM56_RS17690	COG0395	ABC-type sugar transport system, permease component
XM56_RS17695	COG1175	transmembrane transport
XM56_RS17700	COG1653	transport
XM56_RS17715	COG1982	Orn Lys Arg decarboxylase major
XM56_RS17720	COG0531	amino acid
XM56_RS17725	COG2827	Endonuclease containing a URI domain
XM56_RS17730	COG3153	acetyltransferase
XM56_RS17735	COG3154	lipid carrier protein
XM56_RS17740	COG0826	peptidase U32
XM56_RS17745	COG0826	peptidase U32
XM56_RS17750	COG3681	Belongs to the UPF0597 family
XM56_RS17755	COG0814	amino acid
XM56_RS17765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
XM56_RS17775	COG0513	Belongs to the DEAD box helicase family
XM56_RS17785	COG1185	polyribonucleotide nucleotidyltransferase activity
XM56_RS17790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
XM56_RS17795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
XM56_RS17800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
XM56_RS17805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
XM56_RS17810	COG0195	Participates in both transcription termination and antitermination
XM56_RS17815	COG0779	Required for maturation of 30S ribosomal subunits
XM56_RS17830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
XM56_RS17835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
XM56_RS17840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
XM56_RS17850	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
XM56_RS17855	COG1534	Rna-binding protein
XM56_RS17865	COG2027	D-alanyl-D-alanine carboxypeptidase
XM56_RS17870	COG0745	RESPONSE REGULATOR receiver
XM56_RS17875	COG0642	Histidine kinase
XM56_RS17880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
XM56_RS17885	COG0697	spore germination
XM56_RS17890	COG0211	Belongs to the bacterial ribosomal protein bL27 family
XM56_RS17895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
XM56_RS17900	COG0142	geranyltranstransferase activity
XM56_RS17910	COG3423	Transcriptional regulator
XM56_RS17915	COG0039	L-malate dehydrogenase activity
XM56_RS17920	COG1438	arginine binding
XM56_RS17930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
XM56_RS17935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
XM56_RS17945	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
XM56_RS17950	COG2105	PFAM AIG2 family protein
XM56_RS17965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
XM56_RS17970	COG1253	flavin adenine dinucleotide binding
XM56_RS17980	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
XM56_RS17985	COG1218	3'(2'),5'-bisphosphate nucleotidase
XM56_RS17990	COG0737	Belongs to the 5'-nucleotidase family
XM56_RS18000	COG0545	Peptidyl-prolyl cis-trans isomerase
XM56_RS18005	COG3061	Opacity-associated protein A
XM56_RS18015	COG0359	binds to the 23S rRNA
XM56_RS18020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
XM56_RS18025	COG2965	DNA replication, synthesis of RNA primer
XM56_RS18030	COG0360	Binds together with S18 to 16S ribosomal RNA
XM56_RS18040	COG1073	alpha beta
XM56_RS18045	COG3650	response to hydrogen peroxide
XM56_RS18050	COG1960	acyl-CoA dehydrogenase activity
XM56_RS18055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XM56_RS18060	COG0557	exoribonuclease II activity
XM56_RS18065	COG1959	2 iron, 2 sulfur cluster binding
XM56_RS18070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
XM56_RS18075	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
XM56_RS18080	COG0330	HflC and HflK could
XM56_RS18085	COG0330	HflC and HflK could
XM56_RS18090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
XM56_RS18095	COG1923	regulation of RNA biosynthetic process
XM56_RS18100	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
XM56_RS18105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
XM56_RS18110	COG0860	N-Acetylmuramoyl-L-alanine amidase
XM56_RS18115	COG0802	atpase or kinase
XM56_RS18120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
XM56_RS18120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
XM56_RS18125	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
XM56_RS18135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
XM56_RS18140	COG1162	GTPase activity
XM56_RS18145	COG0688	phosphatidylethanolamine metabolic process
XM56_RS18150	COG3264	Mechanosensitive ion channel
XM56_RS18150	COG1511	domain protein
XM56_RS18155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
XM56_RS18160	COG1053	succinate dehydrogenase
XM56_RS18165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
XM56_RS18170	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
XM56_RS18175	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
XM56_RS18195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
XM56_RS18215	COG0459	protein refolding
XM56_RS18220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
XM56_RS18235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
XM56_RS18245	COG4232	protein-disulfide reductase activity
XM56_RS18250	COG1929	Belongs to the glycerate kinase type-1 family
XM56_RS18255	COG1309	transcriptional regulator
XM56_RS18265	COG1882	Formate acetyltransferase
XM56_RS18270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
XM56_RS18275	COG0814	amino acid
XM56_RS18280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
XM56_RS18290	COG3721	Heme iron utilization protein
XM56_RS18310	COG3720	iron ion transport
XM56_RS18315	COG4558	Periplasmic binding protein
XM56_RS18320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
XM56_RS18325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
XM56_RS18330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
XM56_RS18335	COG4774	siderophore transport
XM56_RS18340	COG1511	domain protein
XM56_RS18340	COG3264	Mechanosensitive ion channel
XM56_RS18345	COG4115	mRNA cleavage
XM56_RS18350	COG2161	toxin-antitoxin pair type II binding
XM56_RS18355	COG0612	Peptidase, M16
XM56_RS18360	COG4178	(ABC) transporter
XM56_RS18365	COG4771	TonB-dependent receptor
XM56_RS18370	COG3712	iron ion homeostasis
XM56_RS18385	COG0425	Belongs to the sulfur carrier protein TusA family
XM56_RS18390	COG2391	methyltransferase activity
XM56_RS18545	COG0784	Response regulator, receiver
XM56_RS18545	COG5002	protein histidine kinase activity
XM56_RS18545	COG2205	protein histidine kinase activity
XM56_RS18550	COG2197	response regulator
XM56_RS18555	COG1301	dicarboxylic acid transport
XM56_RS18560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
XM56_RS18565	COG3162	membrane
XM56_RS18570	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
XM56_RS18615	COG0138	bifunctional purine biosynthesis protein purh
XM56_RS18620	COG0151	Belongs to the GarS family
XM56_RS18640	COG1515	deoxyribonuclease V activity
XM56_RS18645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
XM56_RS18650	COG2816	NAD+ diphosphatase activity
XM56_RS18655	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
XM56_RS18670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
XM56_RS18675	COG2104	thiamine diphosphate biosynthetic process
XM56_RS18680	COG2022	thiamine diphosphate biosynthetic process
XM56_RS18695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
XM56_RS18700	COG0085	RNA polymerase activity
XM56_RS18705	COG0222	ribosome binding
XM56_RS18710	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
XM56_RS18715	COG0081	regulation of translation
XM56_RS18720	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
XM56_RS18725	COG0250	Participates in transcription elongation, termination and antitermination
XM56_RS18735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
XM56_RS18765	COG1072	(Pantothenic acid kinase))
XM56_RS18770	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
XM56_RS18770	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
XM56_RS18815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
XM56_RS18820	COG1739	Uncharacterized protein family UPF0029
XM56_RS18825	COG0006	proline dipeptidase activity
XM56_RS18830	COG1024	Enoyl-CoA hydratase
XM56_RS18830	COG1250	3-hydroxyacyl-CoA dehydrogenase
XM56_RS18835	COG0183	Belongs to the thiolase family
XM56_RS18845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
XM56_RS18865	COG0805	protein transport
XM56_RS18870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XM56_RS18875	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
XM56_RS18880	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
XM56_RS18890	COG2226	methyltransferase
XM56_RS18895	COG1322	Protein conserved in bacteria
XM56_RS18900	COG0586	Pfam SNARE associated Golgi protein
XM56_RS18905	COG1966	Carbon starvation protein
XM56_RS18925	COG0412	Dienelactone hydrolase
XM56_RS18930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
XM56_RS18935	COG0583	DNA-binding transcription factor activity
XM56_RS18940	COG0697	spore germination
XM56_RS18945	COG0679	Auxin Efflux Carrier
XM56_RS18950	COG0584	glycerophosphoryl diester phosphodiesterase
XM56_RS18955	COG3842	ATPase activity
XM56_RS18960	COG0395	ABC-type sugar transport system, permease component
XM56_RS18965	COG1175	transmembrane transport
XM56_RS18970	COG1653	transport
XM56_RS19005	COG0410	ABC transporter
XM56_RS19015	COG4177	L-phenylalanine transmembrane transporter activity
XM56_RS19025	COG0683	leucine binding
XM56_RS19050	COG2177	Part of the ABC transporter FtsEX involved in
XM56_RS19055	COG2884	Cell division ATP-binding protein ftsE
XM56_RS19060	COG0552	protein localization to endoplasmic reticulum
XM56_RS19065	COG0742	ribosomal rna small subunit methyltransferase
XM56_RS19070	COG3776	membrane
XM56_RS19085	COG3714	YhhN family
XM56_RS19090	COG2217	Heavy metal translocating P-type atpase
XM56_RS19095	COG0425	Belongs to the sulfur carrier protein TusA family
XM56_RS19100	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
XM56_RS19110	COG0247	lactate metabolic process
XM56_RS19115	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
XM56_RS19120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
XM56_RS19125	COG2271	Major facilitator Superfamily
XM56_RS19130	COG0584	glycerophosphoryl diester phosphodiesterase
XM56_RS19135	COG0561	phosphatase activity
XM56_RS19140	COG2267	carboxylic ester hydrolase activity
XM56_RS19145	COG1280	lysine exporter protein (LysE YggA)
XM56_RS19150	COG1280	lysine exporter protein (LysE YggA)
XM56_RS19155	COG0514	ATP-dependent DNA helicase (RecQ)
XM56_RS19160	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
XM56_RS19165	COG2050	protein possibly involved in aromatic compounds catabolism
XM56_RS19180	COG5564	TIM-barrel signal transduction protein
XM56_RS19185	COG5441	Belongs to the UPF0261 family
XM56_RS19195	COG0210	DNA helicase
XM56_RS19200	COG1011	Hydrolase
XM56_RS19205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
XM56_RS19210	COG3159	Protein conserved in bacteria
XM56_RS19215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
XM56_RS19225	COG1965	Belongs to the frataxin family
XM56_RS19230	COG3072	Adenylate cyclase
XM56_RS19235	COG0181	hydroxymethylbilane synthase activity
XM56_RS19240	COG1587	Uroporphyrinogen-III synthase
XM56_RS19245	COG2959	enzyme of heme biosynthesis
XM56_RS19250	COG3071	HemY protein
XM56_RS19300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
XM56_RS19305	COG2244	polysaccharide biosynthetic process
XM56_RS19310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
XM56_RS19315	COG0456	acetyltransferase
XM56_RS19320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
XM56_RS19325	COG1088	dTDP-glucose 4,6-dehydratase activity
XM56_RS19330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
XM56_RS19335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
XM56_RS19340	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
XM56_RS19345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
XM56_RS19355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
XM56_RS19360	COG3118	belongs to the thioredoxin family
XM56_RS19370	COG0248	Ppx GppA phosphatase
XM56_RS19385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
XM56_RS19395	COG3121	Chaperone
XM56_RS19410	COG3121	Chaperone
XM56_RS19435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
XM56_RS19440	COG0583	DNA-binding transcription factor activity
XM56_RS19465	COG0129	dihydroxy-acid dehydratase activity
XM56_RS19470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
XM56_RS19475	COG3978	acetolactate synthase activity
XM56_RS19490	COG3085	chromosome segregation
XM56_RS19495	COG0583	DNA-binding transcription factor activity
XM56_RS19500	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS19505	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS19510	COG1129	ABC transporter
XM56_RS19515	COG1879	ABC-type sugar transport system periplasmic component
XM56_RS19555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
XM56_RS19565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
XM56_RS19575	COG1309	transcriptional regulator
XM56_RS19580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XM56_RS19590	COG0678	peroxiredoxin activity
XM56_RS19590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XM56_RS19595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
XM56_RS19630	COG1629	transport
XM56_RS19635	COG0165	Argininosuccinate lyase
XM56_RS19640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
XM56_RS19655	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
XM56_RS19665	COG0460	homoserine dehydrogenase
XM56_RS19665	COG0527	aspartate kinase activity
XM56_RS19670	COG0626	cystathionine gamma-synthase activity
XM56_RS19675	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
XM56_RS19680	COG0254	rRNA binding
XM56_RS19685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
XM56_RS19690	COG1609	Transcriptional regulator
XM56_RS19695	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
XM56_RS19700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
XM56_RS19705	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
XM56_RS19710	COG1575	Belongs to the MenA family. Type 1 subfamily
XM56_RS19715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
XM56_RS19720	COG3074	FtsZ-dependent cytokinesis
XM56_RS19725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
XM56_RS19735	COG1494	fructose-1,6-bisphosphatase
XM56_RS19740	COG2814	Major facilitator Superfamily
XM56_RS19760	COG3152	Membrane
XM56_RS19770	COG0149	triose-phosphate isomerase activity
XM56_RS19780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
XM56_RS19790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
XM56_RS19795	COG3678	ATP-independent chaperone mediated protein folding
XM56_RS19800	COG0745	RESPONSE REGULATOR receiver
XM56_RS19805	COG2205	protein histidine kinase activity
XM56_RS19810	COG2169	Transcriptional regulator
XM56_RS19810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
XM56_RS19815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
XM56_RS19820	COG1045	serine acetyltransferase
XM56_RS19825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
XM56_RS19830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
XM56_RS19835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
XM56_RS19840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
XM56_RS19845	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
XM56_RS19850	COG4942	peptidase
XM56_RS19855	COG2861	carbohydrate metabolic process
XM56_RS19875	COG1063	alcohol dehydrogenase
XM56_RS19880	COG0156	8-amino-7-oxononanoate synthase activity
XM56_RS19885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
XM56_RS19890	COG0859	PFAM glycosyl transferase family 9
XM56_RS19895	COG0859	PFAM glycosyl transferase family 9
XM56_RS19900	COG1519	Transferase
XM56_RS19910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
XM56_RS19915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
XM56_RS19920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
XM56_RS19925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
XM56_RS19930	COG2003	Belongs to the UPF0758 family
XM56_RS19935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
XM56_RS19940	COG0756	dUTP diphosphatase activity
XM56_RS19945	COG1309	transcriptional regulator
XM56_RS19950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
XM56_RS19955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
XM56_RS19960	COG1561	YicC-like family, N-terminal region
XM56_RS19975	COG5001	Diguanylate cyclase
XM56_RS19980	COG1024	Enoyl-CoA hydratase
XM56_RS19985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
XM56_RS19995	COG2860	membrane
XM56_RS20000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
XM56_RS20010	COG1758	RNA polymerase activity
XM56_RS20015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
XM56_RS20020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
XM56_RS20025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
XM56_RS20035	COG0786	glutamate:sodium symporter activity
XM56_RS20040	COG2233	PERMEase
XM56_RS20045	COG2982	Protein involved in outer membrane biogenesis
XM56_RS20060	COG3423	Transcriptional regulator
XM56_RS20065	COG0456	acetyltransferase
XM56_RS20070	COG1490	D-aminoacyl-tRNA deacylase activity
XM56_RS20075	COG1295	ribonuclease BN
XM56_RS20080	COG1011	Hydrolase
XM56_RS20100	COG3852	Histidine kinase
XM56_RS20110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
XM56_RS20115	COG3078	GTPase activator activity
XM56_RS20120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
XM56_RS20125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XM56_RS20125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
XM56_RS20130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
XM56_RS20135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
XM56_RS20140	COG3084	Protein conserved in bacteria
XM56_RS20150	COG1763	Mo-molybdopterin cofactor biosynthetic process
XM56_RS20190	COG2186	Transcriptional regulator
XM56_RS20200	COG1609	Transcriptional regulator
XM56_RS20205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
XM56_RS20210	COG1879	ABC-type sugar transport system periplasmic component
XM56_RS20215	COG1172	Belongs to the binding-protein-dependent transport system permease family
XM56_RS20225	COG1869	D-ribose catabolic process
XM56_RS20230	COG3158	transport of potassium into the cell
XM56_RS20235	COG0714	Associated with various cellular activities
XM56_RS20240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
XM56_RS20250	COG2502	aspartate--ammonia ligase
XM56_RS20255	COG1522	sequence-specific DNA binding
XM56_RS20260	COG0716	FMN binding
XM56_RS20265	COG0445	tRNA wobble uridine modification
XM56_RS20270	COG0357	Ribosomal RNA small subunit methyltransferase G
XM56_RS20275	COG3312	ion transport
XM56_RS20280	COG0356	it plays a direct role in the translocation of protons across the membrane
XM56_RS20290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
XM56_RS20295	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
XM56_RS20300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
XM56_RS20305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
XM56_RS20310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
XM56_RS20315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
XM56_RS20320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
XM56_RS20335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
XM56_RS20340	COG0573	inorganic phosphate transmembrane transporter activity
XM56_RS20345	COG0581	inorganic phosphate transmembrane transporter activity
XM56_RS20355	COG0704	Plays a role in the regulation of phosphate uptake
XM56_RS20365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
XM56_RS20370	COG0765	amino acid transport
XM56_RS20375	COG0765	amino acid transport
XM56_RS20380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
XM56_RS20385	COG2252	PERMEase
XM56_RS20395	COG4566	intracellular signal transduction
XM56_RS20405	COG0431	NADPH-dependent FMN reductase
XM56_RS20410	COG0840	transmembrane signaling receptor activity
XM56_RS20415	COG2011	ABC-type metal ion transport system permease component
XM56_RS20420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
XM56_RS20430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
XM56_RS20435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
XM56_RS20440	COG0706	membrane insertase activity
XM56_RS20450	COG0594	ribonuclease P activity
XM56_RS20455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
XM56_RS20645	COG0752	glycyl-tRNA synthetase alpha subunit
XM56_RS20700	COG3722	fumarate hydratase activity
XM56_RS20755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
XM56_RS20820	COG3276	selenocysteine insertion sequence binding
XM56_RS20910	COG4214	carbohydrate transport