locus-tag	class	description
CH47_RS00150	COG1283	sodium-dependent phosphate transmembrane transporter activity
CH47_RS00410	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CH47_RS00415	COG5557	Pfam Polysulphide reductase, NrfD
CH47_RS00420	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CH47_RS00425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CH47_RS00430	COG1773	rubredoxin
CH47_RS00440	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH47_RS00445	COG0298	carbon dioxide binding
CH47_RS00450	COG0409	Hydrogenase expression formation protein
CH47_RS00455	COG0309	Hydrogenase expression formation protein (HypE)
CH47_RS00460	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CH47_RS00465	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CH47_RS00480	COG5001	Diguanylate cyclase
CH47_RS00495	COG0477	Major facilitator Superfamily
CH47_RS00510	COG1283	sodium-dependent phosphate transmembrane transporter activity
CH47_RS00520	COG1609	Transcriptional regulator
CH47_RS00525	COG0477	Major facilitator Superfamily
CH47_RS00540	COG4607	ABC-type enterochelin transport system periplasmic component
CH47_RS00550	COG4605	iron ion homeostasis
CH47_RS00555	COG4604	ABC transporter, ATP-binding protein
CH47_RS00560	COG0024	Methionine aminopeptidase
CH47_RS00570	COG0745	RESPONSE REGULATOR receiver
CH47_RS00585	COG3397	chitin binding
CH47_RS00595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CH47_RS00630	COG2165	general secretion pathway protein
CH47_RS00640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH47_RS00675	COG0745	RESPONSE REGULATOR receiver
CH47_RS00680	COG2197	response regulator
CH47_RS00850	COG1289	transmembrane transporter activity
CH47_RS00860	COG1982	Orn Lys Arg decarboxylase major
CH47_RS00865	COG0531	amino acid
CH47_RS00915	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH47_RS00930	COG1982	Orn Lys Arg decarboxylase major
CH47_RS00940	COG0741	lytic transglycosylase activity
CH47_RS00945	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CH47_RS00950	COG1194	a g-specific adenine glycosylase
CH47_RS00955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CH47_RS00960	COG3171	Protein conserved in bacteria
CH47_RS00975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH47_RS00980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH47_RS00985	COG1872	DUF167
CH47_RS00990	COG0762	integral membrane protein
CH47_RS00995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH47_RS01000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH47_RS01005	COG2805	Type II/IV secretion system protein
CH47_RS01015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH47_RS01020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CH47_RS01025	COG1678	Uncharacterized ACR, COG1678
CH47_RS01030	COG0189	ligase activity
CH47_RS01035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH47_RS01040	COG2356	endonuclease I
CH47_RS01045	COG3091	SprT-like family
CH47_RS01050	COG0640	Transcriptional regulator
CH47_RS01065	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CH47_RS01070	COG1166	arginine decarboxylase activity
CH47_RS01080	COG0501	Belongs to the peptidase M48B family
CH47_RS01085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH47_RS01115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CH47_RS01120	COG0126	phosphoglycerate kinase activity
CH47_RS01125	COG0191	fructose-bisphosphate aldolase activity
CH47_RS01140	COG1279	arginine transmembrane transporter activity
CH47_RS01150	COG0583	DNA-binding transcription factor activity
CH47_RS01155	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CH47_RS01160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH47_RS01165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH47_RS01170	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CH47_RS01175	COG3079	Belongs to the UPF0149 family
CH47_RS01180	COG0006	proline dipeptidase activity
CH47_RS01185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH47_RS01190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH47_RS01195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CH47_RS01200	COG0509	glycine decarboxylation via glycine cleavage system
CH47_RS01205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH47_RS01205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CH47_RS01220	COG1272	protein, Hemolysin III
CH47_RS01225	COG0354	folic acid binding
CH47_RS01240	COG0745	RESPONSE REGULATOR receiver
CH47_RS01245	COG2205	protein histidine kinase activity
CH47_RS01250	COG4452	Inner membrane protein CreD
CH47_RS01255	COG0716	FMN binding
CH47_RS01260	COG4974	Belongs to the 'phage' integrase family
CH47_RS01265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH47_RS01270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH47_RS01275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CH47_RS01280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CH47_RS01310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH47_RS01315	COG1393	Belongs to the ArsC family
CH47_RS01320	COG4319	ketosteroid isomerase
CH47_RS01325	COG3706	GGDEF domain
CH47_RS01330	COG1522	sequence-specific DNA binding
CH47_RS01345	COG2271	Major facilitator Superfamily
CH47_RS01350	COG1609	Transcriptional regulator
CH47_RS01355	COG0484	heat shock protein binding
CH47_RS01365	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS01370	COG1733	regulation of RNA biosynthetic process
CH47_RS01375	COG0288	reversible hydration of carbon dioxide
CH47_RS01395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH47_RS01405	COG2165	general secretion pathway protein
CH47_RS01435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CH47_RS01450	COG0840	transmembrane signaling receptor activity
CH47_RS01470	COG2814	Major facilitator Superfamily
CH47_RS01475	COG0583	DNA-binding transcription factor activity
CH47_RS01485	COG1609	Transcriptional regulator
CH47_RS01495	COG0318	PFAM AMP-dependent synthetase and ligase
CH47_RS01495	COG0204	Acyl-transferase
CH47_RS01500	COG0477	Major facilitator Superfamily
CH47_RS01505	COG0667	Aldo Keto reductase
CH47_RS01510	COG0861	Integral membrane protein TerC family
CH47_RS01515	COG3066	DNA modification
CH47_RS01525	COG1051	belongs to the nudix hydrolase family
CH47_RS01535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CH47_RS01540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CH47_RS01545	COG2165	general secretion pathway protein
CH47_RS01565	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH47_RS01570	COG1025	Belongs to the peptidase M16 family
CH47_RS01575	COG1074	ATP-dependent DNA helicase activity
CH47_RS01580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH47_RS01585	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CH47_RS01585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CH47_RS01590	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH47_RS01615	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH47_RS01620	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH47_RS01625	COG2166	iron-sulfur cluster assembly
CH47_RS01630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH47_RS01640	COG0583	DNA-binding transcription factor activity
CH47_RS01645	COG2363	Small membrane protein
CH47_RS01650	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CH47_RS01655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH47_RS01660	COG1611	Belongs to the LOG family
CH47_RS01665	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CH47_RS01665	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CH47_RS01675	COG3098	single-species biofilm formation
CH47_RS01680	COG0564	pseudouridine synthase activity
CH47_RS01695	COG2171	N-acyltransferase activity
CH47_RS01700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CH47_RS01710	COG0052	Belongs to the universal ribosomal protein uS2 family
CH47_RS01715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CH47_RS01720	COG0528	UMP kinase activity
CH47_RS01725	COG0233	cytoplasmic translational termination
CH47_RS01730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CH47_RS01740	COG0575	Belongs to the CDS family
CH47_RS01745	COG0750	zinc metalloprotease
CH47_RS01755	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CH47_RS01760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH47_RS01765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH47_RS01770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH47_RS01780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CH47_RS01785	COG0587	DNA-directed DNA polymerase activity
CH47_RS01790	COG0825	malonyl-CoA metabolic process
CH47_RS01795	COG1982	Orn Lys Arg decarboxylase major
CH47_RS01800	COG0346	lactoylglutathione lyase activity
CH47_RS01815	COG4568	rho-dependent transcription termination
CH47_RS01825	COG4681	YaeQ
CH47_RS01835	COG3015	lipoprotein NlpE involved in copper resistance
CH47_RS01840	COG0442	prolyl-tRNA aminoacylation
CH47_RS01845	COG1720	tRNA m6t6A37 methyltransferase activity
CH47_RS01855	COG1464	Belongs to the NlpA lipoprotein family
CH47_RS01860	COG2011	ABC-type metal ion transport system permease component
CH47_RS01870	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH47_RS01930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH47_RS01945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH47_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS01995	COG0656	L-ascorbic acid biosynthetic process
CH47_RS02000	COG0583	DNA-binding transcription factor activity
CH47_RS02005	COG2814	Major facilitator Superfamily
CH47_RS02010	COG3021	interspecies interaction between organisms
CH47_RS02015	COG0741	lytic transglycosylase activity
CH47_RS02015	COG1388	LysM domain
CH47_RS02020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH47_RS02025	COG2226	methyltransferase
CH47_RS02030	COG0328	RNA-DNA hybrid ribonuclease activity
CH47_RS02035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH47_RS02045	COG2113	Glycine betaine
CH47_RS02050	COG4176	ABC-type proline glycine betaine transport system permease component
CH47_RS02055	COG4175	Glycine betaine
CH47_RS02060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH47_RS02070	COG1780	Probably involved in ribonucleotide reductase function
CH47_RS02075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH47_RS02080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH47_RS02090	COG4575	ribosome binding
CH47_RS02105	COG2207	Transcriptional regulator
CH47_RS02110	COG0477	Major facilitator Superfamily
CH47_RS02135	COG1278	Cold shock
CH47_RS02165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH47_RS02170	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH47_RS02185	COG0831	urea catabolic process
CH47_RS02190	COG0832	Belongs to the urease beta subunit family
CH47_RS02195	COG0804	urea catabolic process
CH47_RS02200	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CH47_RS02205	COG0830	nickel cation binding
CH47_RS02210	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH47_RS02215	COG0829	nickel cation binding
CH47_RS02220	COG4413	Urea transporter
CH47_RS02225	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH47_RS02235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH47_RS02255	COG0667	Aldo Keto reductase
CH47_RS02260	COG2133	pyrroloquinoline quinone binding
CH47_RS02265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH47_RS02270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH47_RS02275	COG2723	6-phospho-beta-galactosidase activity
CH47_RS02280	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH47_RS02285	COG2169	Transcriptional regulator
CH47_RS02285	COG1917	Cupin 2, conserved barrel domain protein
CH47_RS02290	COG3394	polysaccharide catabolic process
CH47_RS02295	COG0659	secondary active sulfate transmembrane transporter activity
CH47_RS02300	COG0582	viral genome integration into host DNA
CH47_RS02375	COG0582	viral genome integration into host DNA
CH47_RS02450	COG0582	viral genome integration into host DNA
CH47_RS02455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CH47_RS02460	COG2867	negative regulation of translational initiation
CH47_RS02470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH47_RS02475	COG0497	DNA recombination
CH47_RS02480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH47_RS02485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CH47_RS02495	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CH47_RS02500	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
CH47_RS02515	COG0513	Belongs to the DEAD box helicase family
CH47_RS02520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CH47_RS02525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH47_RS02535	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CH47_RS02545	COG3086	response to oxidative stress
CH47_RS02555	COG0481	GTPase activity
CH47_RS02565	COG0571	ribonuclease III activity
CH47_RS02570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CH47_RS02575	COG1381	Involved in DNA repair and RecF pathway recombination
CH47_RS02580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH47_RS02585	COG0736	holo-[acyl-carrier-protein] synthase activity
CH47_RS02590	COG2610	gluconate transmembrane transporter activity
CH47_RS02595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH47_RS02600	COG1737	Transcriptional regulator
CH47_RS02610	COG3423	Transcriptional regulator
CH47_RS02620	COG0560	Phosphoserine phosphatase
CH47_RS02635	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CH47_RS02655	COG2205	protein histidine kinase activity
CH47_RS02660	COG3170	Tfp pilus assembly protein FimV
CH47_RS02665	COG2204	response regulator
CH47_RS02670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH47_RS02670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH47_RS02675	COG0347	Belongs to the P(II) protein family
CH47_RS02690	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CH47_RS02695	COG3457	Alanine racemase
CH47_RS02705	COG2188	Transcriptional regulator
CH47_RS02710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH47_RS02710	COG1017	nitric oxide dioxygenase activity
CH47_RS02715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CH47_RS02720	COG2814	Major facilitator Superfamily
CH47_RS02725	COG3711	transcriptional antiterminator
CH47_RS02730	COG3683	transport system, periplasmic component
CH47_RS02735	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH47_RS02755	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CH47_RS02760	COG1959	2 iron, 2 sulfur cluster binding
CH47_RS02770	COG0822	iron-sulfur transferase activity
CH47_RS02775	COG0316	Belongs to the HesB IscA family
CH47_RS02780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH47_RS02785	COG0443	Heat shock 70 kDa protein
CH47_RS02790	COG0633	Ferredoxin
CH47_RS02795	COG2975	iron-sulfur cluster assembly
CH47_RS02810	COG2373	Large extracellular alpha-helical protein
CH47_RS02815	COG4953	penicillin-binding protein 1C
CH47_RS02825	COG0105	UTP biosynthetic process
CH47_RS02830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CH47_RS02840	COG1426	Protein conserved in bacteria
CH47_RS02845	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CH47_RS02850	COG0124	histidyl-tRNA synthetase
CH47_RS02855	COG2976	Protein conserved in bacteria
CH47_RS02860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH47_RS02865	COG1160	GTP binding
CH47_RS02875	COG1645	bacterial-type flagellum-dependent swarming motility
CH47_RS02880	COG1570	exodeoxyribonuclease VII activity
CH47_RS02885	COG0517	IMP dehydrogenase activity
CH47_RS02885	COG0516	GMP reductase activity
CH47_RS02890	COG0519	Catalyzes the synthesis of GMP from XMP
CH47_RS02890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CH47_RS02920	COG0351	phosphomethylpyrimidine kinase
CH47_RS02940	COG1349	DNA-binding transcription factor activity
CH47_RS02945	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS02950	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS02965	COG3730	PTS system glucitol sorbitol-specific
CH47_RS02970	COG1597	lipid kinase activity
CH47_RS02975	COG0826	peptidase U32
CH47_RS02990	COG3422	double-strand break repair
CH47_RS02995	COG0745	RESPONSE REGULATOR receiver
CH47_RS03000	COG2205	protein histidine kinase activity
CH47_RS03005	COG0477	Major facilitator Superfamily
CH47_RS03010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH47_RS03020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS03030	COG3539	Fimbrial protein
CH47_RS03040	COG3121	Chaperone
CH47_RS03050	COG0443	Heat shock 70 kDa protein
CH47_RS03055	COG3447	MASE1 domain protein
CH47_RS03055	COG5002	protein histidine kinase activity
CH47_RS03055	COG5001	Diguanylate cyclase
CH47_RS03060	COG2239	Acts as a magnesium transporter
CH47_RS03075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH47_RS03080	COG2801	Transposase and inactivated derivatives
CH47_RS03085	COG2963	transposase activity
CH47_RS03095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH47_RS03100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH47_RS03105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CH47_RS03110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CH47_RS03115	COG2233	PERMEase
CH47_RS03120	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CH47_RS03125	COG1393	Belongs to the ArsC family
CH47_RS03130	COG4783	chaperone-mediated protein folding
CH47_RS03135	COG0628	permease
CH47_RS03140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH47_RS03145	COG2716	regulation of RNA biosynthetic process
CH47_RS03150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH47_RS03155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH47_RS03160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CH47_RS03165	COG2321	neutral zinc metallopeptidase
CH47_RS03170	COG2707	UPF0756 membrane protein
CH47_RS03175	COG1444	tRNA N-acetyltransferase activity
CH47_RS03180	COG0400	carboxylic ester hydrolase activity
CH47_RS03190	COG1876	peptidase activity
CH47_RS03195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CH47_RS03200	COG1393	Belongs to the ArsC family
CH47_RS03215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH47_RS03225	COG2197	response regulator
CH47_RS03235	COG3062	negative regulation of establishment of protein localization
CH47_RS03240	COG0243	molybdopterin cofactor binding
CH47_RS03245	COG3043	anaerobic respiration
CH47_RS03250	COG3005	denitrification pathway
CH47_RS03265	COG0494	nUDIX hydrolase
CH47_RS03275	COG2197	response regulator
CH47_RS03285	COG1671	Belongs to the UPF0178 family
CH47_RS03290	COG0408	coproporphyrinogen oxidase activity
CH47_RS03295	COG0456	acetyltransferase
CH47_RS03300	COG3111	PFAM Bacterial OB fold (BOF) protein
CH47_RS03310	COG2837	iron assimilation
CH47_RS03315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH47_RS03330	COG2731	YhcH YjgK YiaL family protein
CH47_RS03335	COG1737	Transcriptional regulator
CH47_RS03345	COG4150	thiosulfate binding
CH47_RS03350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH47_RS03355	COG4208	sulfate ABC transporter
CH47_RS03375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS03380	COG0745	RESPONSE REGULATOR receiver
CH47_RS03385	COG2205	protein histidine kinase activity
CH47_RS03395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH47_RS03400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS03420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH47_RS03425	COG3530	Putative quorum-sensing-regulated virulence factor
CH47_RS03455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH47_RS03480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH47_RS03485	COG1914	H( )-stimulated, divalent metal cation uptake system
CH47_RS03495	COG0667	Aldo Keto reductase
CH47_RS03500	COG3961	Belongs to the TPP enzyme family
CH47_RS03515	COG0837	glucose binding
CH47_RS03520	COG2223	nitrite transmembrane transporter activity
CH47_RS03525	COG3279	Response regulator of the LytR AlgR family
CH47_RS03530	COG3275	phosphorelay sensor kinase activity
CH47_RS03545	COG0436	Aminotransferase
CH47_RS03550	COG3038	cytochrome b561
CH47_RS03555	COG1598	PFAM Uncharacterised protein family UPF0150
CH47_RS03585	COG1280	lysine exporter protein (LysE YggA)
CH47_RS03605	COG2951	lytic endotransglycosylase activity
CH47_RS03610	COG0531	amino acid
CH47_RS03635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH47_RS03640	COG1127	ABC transporter
CH47_RS03660	COG0657	acetylesterase activity
CH47_RS03660	COG2755	lipolytic protein G-D-S-L family
CH47_RS03665	COG3038	cytochrome b561
CH47_RS03670	COG2353	YceI-like domain
CH47_RS03675	COG1609	Transcriptional regulator
CH47_RS03680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS03680	COG1263	PTS System
CH47_RS03685	COG2723	6-phospho-beta-galactosidase activity
CH47_RS03695	COG1695	Transcriptional regulator
CH47_RS03700	COG2824	Alkylphosphonate utilization operon protein PhnA
CH47_RS03705	COG0582	viral genome integration into host DNA
CH47_RS03765	COG0582	viral genome integration into host DNA
CH47_RS03775	COG2116	formate transmembrane transporter activity
CH47_RS03785	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH47_RS03790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH47_RS03795	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH47_RS03800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CH47_RS03805	COG1138	Cytochrome C-type biogenesis protein
CH47_RS03810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH47_RS03820	COG4235	cytochrome complex assembly
CH47_RS03820	COG3088	subunit of a heme lyase
CH47_RS03845	COG3691	Protein conserved in bacteria
CH47_RS03850	COG0183	Belongs to the thiolase family
CH47_RS03855	COG1024	Enoyl-CoA hydratase
CH47_RS03855	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH47_RS03860	COG2062	phosphohistidine phosphatase, SixA
CH47_RS03865	COG2840	Smr protein MutS2
CH47_RS03870	COG2890	protein-(glutamine-N5) methyltransferase activity
CH47_RS03875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CH47_RS03880	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CH47_RS03885	COG0730	response to heat
CH47_RS03890	COG3101	peptidyl-lysine hydroxylation
CH47_RS03900	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CH47_RS03900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH47_RS03905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH47_RS03915	COG1794	racemase activity, acting on amino acids and derivatives
CH47_RS03925	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH47_RS03930	COG2723	6-phospho-beta-galactosidase activity
CH47_RS03935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH47_RS03945	COG1609	Transcriptional regulator
CH47_RS03955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH47_RS03980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH47_RS03985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH47_RS03990	COG0697	spore germination
CH47_RS03995	COG0697	spore germination
CH47_RS04005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH47_RS04010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH47_RS04020	COG0586	Pfam SNARE associated Golgi protein
CH47_RS04025	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CH47_RS04030	COG0285	dihydrofolate synthase activity
CH47_RS04035	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH47_RS04040	COG1286	toxin biosynthetic process
CH47_RS04045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH47_RS04050	COG0163	prenyltransferase activity
CH47_RS04055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS04060	COG4215	(ABC) transporter
CH47_RS04065	COG4160	amino acid transport
CH47_RS04070	COG4598	ABC transporter
CH47_RS04080	COG1090	epimerase
CH47_RS04095	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH47_RS04110	COG3037	sugar-specific permease SgaT UlaA
CH47_RS04120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS04125	COG1609	Transcriptional regulator
CH47_RS04135	COG0857	belongs to the CobB CobQ family
CH47_RS04135	COG0280	phosphate acetyltransferase
CH47_RS04145	COG3092	negative regulation of chromosome organization
CH47_RS04150	COG3013	Belongs to the UPF0304 family
CH47_RS04155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH47_RS04165	COG0490	domain, Protein
CH47_RS04165	COG0471	metal ion transport
CH47_RS04170	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CH47_RS04175	COG0436	Aminotransferase
CH47_RS04180	COG0583	DNA-binding transcription factor activity
CH47_RS04190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS04195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS04200	COG0649	NAD binding
CH47_RS04200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS04215	COG1034	ATP synthesis coupled electron transport
CH47_RS04220	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CH47_RS04225	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS04230	COG0839	Belongs to the complex I subunit 6 family
CH47_RS04235	COG0713	ATP synthesis coupled electron transport
CH47_RS04240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH47_RS04245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS04250	COG1007	ATP synthesis coupled electron transport
CH47_RS04285	COG3265	gluconokinase activity
CH47_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS04295	COG1609	Transcriptional regulator
CH47_RS04300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH47_RS04310	COG4702	Belongs to the UPF0303 family
CH47_RS04315	COG0129	dihydroxy-acid dehydratase activity
CH47_RS04335	COG4575	ribosome binding
CH47_RS04345	COG1169	isochorismate synthase
CH47_RS04350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CH47_RS04355	COG0596	Alpha beta hydrolase
CH47_RS04360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH47_RS04365	COG1441	menaquinone biosynthetic process
CH47_RS04385	COG0814	amino acid
CH47_RS04410	COG4574	serine-type endopeptidase inhibitor activity
CH47_RS04415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH47_RS04425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH47_RS04430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH47_RS04440	COG2205	protein histidine kinase activity
CH47_RS04440	COG0784	Response regulator, receiver
CH47_RS04445	COG2197	response regulator
CH47_RS04450	COG2198	Histidine kinase
CH47_RS04450	COG0642	Histidine kinase
CH47_RS04455	COG2223	nitrite transmembrane transporter activity
CH47_RS04470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CH47_RS04485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH47_RS04535	COG1737	Transcriptional regulator
CH47_RS04540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS04540	COG2190	(PTS) system
CH47_RS04540	COG1263	PTS System
CH47_RS04545	COG2723	6-phospho-beta-galactosidase activity
CH47_RS04565	COG3082	Protein of unknown function (DUF1414)
CH47_RS04570	COG3081	Nucleoid-associated protein
CH47_RS04575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CH47_RS04580	COG1061	Type III restriction enzyme res subunit
CH47_RS04585	COG1187	pseudouridine synthase activity
CH47_RS04590	COG2814	Major facilitator Superfamily
CH47_RS04600	COG4172	Belongs to the ABC transporter superfamily
CH47_RS04605	COG4239	(ABC) transporter, permease
CH47_RS04610	COG4174	ABC transporter (Permease)
CH47_RS04615	COG4166	transmembrane transport
CH47_RS04630	COG0791	NLP P60 protein
CH47_RS04635	COG0671	phosphoesterase, PA-phosphatase related
CH47_RS04640	COG0523	cobalamin synthesis protein
CH47_RS04650	COG2186	Transcriptional regulator
CH47_RS04655	COG0246	Mannitol dehydrogenase
CH47_RS04660	COG1312	Catalyzes the dehydration of D-mannonate
CH47_RS04665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CH47_RS04680	COG0243	molybdopterin cofactor binding
CH47_RS04685	COG3005	denitrification pathway
CH47_RS04700	COG1105	Belongs to the carbohydrate kinase PfkB family
CH47_RS04705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH47_RS04705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH47_RS04705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH47_RS04710	COG3710	Transcriptional regulator
CH47_RS04735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CH47_RS04740	COG2855	membrane
CH47_RS04745	COG0583	DNA-binding transcription factor activity
CH47_RS04750	COG0833	amino acid
CH47_RS04755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH47_RS04765	COG4771	TonB-dependent receptor
CH47_RS04770	COG0625	glutathione transferase activity
CH47_RS04795	COG2011	ABC-type metal ion transport system permease component
CH47_RS04800	COG0626	cystathionine gamma-synthase activity
CH47_RS04810	COG1686	Belongs to the peptidase S11 family
CH47_RS04815	COG1760	l-serine dehydratase
CH47_RS04820	COG0814	amino acid
CH47_RS04825	COG1349	DNA-binding transcription factor activity
CH47_RS04830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH47_RS04835	COG0671	phosphoesterase, PA-phosphatase related
CH47_RS04910	COG4695	Portal protein
CH47_RS05035	COG0569	domain protein
CH47_RS05035	COG2985	domain, Protein
CH47_RS05065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH47_RS05070	COG3842	ATPase activity
CH47_RS05075	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH47_RS05080	COG1177	transmembrane transport
CH47_RS05090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH47_RS05095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS05100	COG4160	amino acid transport
CH47_RS05105	COG4215	(ABC) transporter
CH47_RS05110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS05115	COG1126	abc transporter atp-binding protein
CH47_RS05125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS05130	COG0702	epimerase
CH47_RS05135	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH47_RS05145	COG0028	Belongs to the TPP enzyme family
CH47_RS05150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH47_RS05155	COG1151	hydroxylamine reductase activity
CH47_RS05160	COG2431	L-lysine efflux transmembrane transporter activity
CH47_RS05165	COG3593	DNA synthesis involved in DNA repair
CH47_RS05170	COG2990	Protein conserved in bacteria
CH47_RS05175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS05185	COG1278	Cold shock
CH47_RS05190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CH47_RS05195	COG0542	response to heat
CH47_RS05200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH47_RS05205	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CH47_RS05215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH47_RS05225	COG0492	ferredoxin-NADP+ reductase activity
CH47_RS05230	COG1522	sequence-specific DNA binding
CH47_RS05235	COG1674	ftsk spoiiie
CH47_RS05235	COG3107	peptidoglycan biosynthetic process
CH47_RS05240	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CH47_RS05245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH47_RS05250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CH47_RS05255	COG2814	Major facilitator Superfamily
CH47_RS05260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH47_RS05265	COG1882	Formate acetyltransferase
CH47_RS05270	COG2116	formate transmembrane transporter activity
CH47_RS05275	COG1944	ATP diphosphatase activity
CH47_RS05280	COG0252	asparaginase activity
CH47_RS05285	COG2323	membrane
CH47_RS05290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CH47_RS05295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CH47_RS05300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CH47_RS05305	COG0539	negative regulation of cytoplasmic translation
CH47_RS05310	COG0776	regulation of translation
CH47_RS05315	COG2333	competence protein COMEC
CH47_RS05315	COG0658	competence protein
CH47_RS05325	COG1663	tetraacyldisaccharide 4'-kinase activity
CH47_RS05330	COG5383	Protein conserved in bacteria
CH47_RS05340	COG1278	Cold shock
CH47_RS05345	COG2835	tetraacyldisaccharide 4'-kinase activity
CH47_RS05350	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CH47_RS05355	COG3173	Aminoglycoside phosphotransferase
CH47_RS05360	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CH47_RS05365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH47_RS05370	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
CH47_RS05380	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CH47_RS05385	COG2989	Protein conserved in bacteria
CH47_RS05390	COG3108	Peptidase M15
CH47_RS05395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH47_RS05400	COG2200	EAL domain
CH47_RS05405	COG1448	Aminotransferase
CH47_RS05415	COG0017	Asparaginyl-tRNA synthetase
CH47_RS05420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CH47_RS05425	COG0308	aminopeptidase N
CH47_RS05430	COG0167	dihydroorotate dehydrogenase activity
CH47_RS05440	COG3217	Mosc domain protein beta barrel domain protein
CH47_RS05440	COG0633	Ferredoxin
CH47_RS05445	COG0116	Belongs to the methyltransferase superfamily
CH47_RS05445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CH47_RS05450	COG0488	(ABC) transporter
CH47_RS05455	COG2995	paraquat-inducible protein a
CH47_RS05460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH47_RS05460	COG3008	intermembrane lipid transfer
CH47_RS05465	COG3009	Protein conserved in bacteria
CH47_RS05470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH47_RS05480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH47_RS05485	COG1067	ATP-dependent peptidase activity
CH47_RS05490	COG3120	sequence-specific DNA binding
CH47_RS05500	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
CH47_RS05505	COG3070	regulator of competence-specific genes
CH47_RS05510	COG1289	transmembrane transporter activity
CH47_RS05515	COG3304	Inner membrane component domain
CH47_RS05520	COG0210	DNA helicase
CH47_RS05525	COG1803	Methylglyoxal synthase
CH47_RS05535	COG1832	CoA-binding protein
CH47_RS05540	COG3785	DNA binding
CH47_RS05545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CH47_RS05560	COG1254	Belongs to the acylphosphatase family
CH47_RS05565	COG2920	part of a sulfur-relay system
CH47_RS05575	COG4235	cytochrome complex assembly
CH47_RS05580	COG2771	luxR family
CH47_RS05585	COG3916	Acyl-homoserine-lactone synthase
CH47_RS05595	COG3263	regulation of cellular component size
CH47_RS05610	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CH47_RS05615	COG2943	transferase activity, transferring hexosyl groups
CH47_RS05620	COG5645	(Lipo)protein
CH47_RS05635	COG2814	Major facilitator Superfamily
CH47_RS05640	COG2259	Doxx family
CH47_RS05645	COG1560	Kdo2-lipid A biosynthetic process
CH47_RS05680	COG1054	Belongs to the UPF0176 family
CH47_RS05685	COG0628	permease
CH47_RS05710	COG0418	dihydroorotase activity
CH47_RS05715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH47_RS05720	COG2801	Transposase and inactivated derivatives
CH47_RS05725	COG2963	transposase activity
CH47_RS05730	COG1530	ribonuclease E activity
CH47_RS05735	COG0564	pseudouridine synthase activity
CH47_RS05740	COG0424	maF-like protein
CH47_RS05745	COG1399	metal-binding, possibly nucleic acid-binding protein
CH47_RS05750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH47_RS05755	COG0416	fatty acid biosynthetic process
CH47_RS05760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH47_RS05765	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH47_RS05780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH47_RS05785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH47_RS05790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH47_RS05795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CH47_RS05800	COG0470	DNA polymerase III
CH47_RS05805	COG0084	hydrolase, TatD family'
CH47_RS05810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS05810	COG1263	PTS System
CH47_RS05845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH47_RS05850	COG0537	adenosine 5'-monophosphoramidase activity
CH47_RS05855	COG5633	Lipoprotein
CH47_RS05860	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
CH47_RS05870	COG1472	Belongs to the glycosyl hydrolase 3 family
CH47_RS05875	COG3150	esterase
CH47_RS05880	COG1252	NADH dehydrogenase
CH47_RS05885	COG3134	Outer membrane lipoprotein
CH47_RS05890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH47_RS05895	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH47_RS05905	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH47_RS05910	COG1940	carbohydrate kinase activity
CH47_RS05925	COG2850	peptidyl-arginine hydroxylation
CH47_RS05935	COG0745	RESPONSE REGULATOR receiver
CH47_RS05945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH47_RS05950	COG2915	High frequency lysogenization protein hflD homolog
CH47_RS05955	COG0482	sulfurtransferase activity
CH47_RS05965	COG1187	pseudouridine synthase activity
CH47_RS05970	COG0538	isocitrate dehydrogenase activity
CH47_RS06005	COG0840	transmembrane signaling receptor activity
CH47_RS06020	COG2873	o-acetylhomoserine
CH47_RS06025	COG0702	epimerase
CH47_RS06030	COG1733	regulation of RNA biosynthetic process
CH47_RS06050	COG3755	Protein conserved in bacteria
CH47_RS06070	COG4191	Histidine kinase
CH47_RS06080	COG5001	Diguanylate cyclase
CH47_RS06080	COG2203	Gaf domain
CH47_RS06080	COG3706	GGDEF domain
CH47_RS06080	COG4251	negative regulation of phosphorylation
CH47_RS06090	COG1132	(ABC) transporter
CH47_RS06115	COG2207	Transcriptional regulator
CH47_RS06150	COG1113	amino acid transport
CH47_RS06170	COG1496	oxidoreductase activity
CH47_RS06175	COG0768	penicillin binding
CH47_RS06180	COG2226	methyltransferase
CH47_RS06190	COG5002	protein histidine kinase activity
CH47_RS06190	COG5001	Diguanylate cyclase
CH47_RS06190	COG3447	MASE1 domain protein
CH47_RS06200	COG1971	Probably functions as a manganese efflux pump
CH47_RS06205	COG4811	Protein of unknown function (DUF986)
CH47_RS06210	COG3716	PTS system mannose fructose sorbose family IID component
CH47_RS06215	COG3715	PTS system
CH47_RS06220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS06220	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS06225	COG1253	flavin adenine dinucleotide binding
CH47_RS06235	COG1760	l-serine dehydratase
CH47_RS06240	COG0494	nUDIX hydrolase
CH47_RS06250	COG3140	Belongs to the UPF0181 family
CH47_RS06255	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CH47_RS06260	COG0513	Belongs to the DEAD box helicase family
CH47_RS06265	COG3141	response to X-ray
CH47_RS06270	COG3097	Belongs to the UPF0267 family
CH47_RS06280	COG1770	oligopeptidase
CH47_RS06285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH47_RS06305	COG1528	Iron-storage protein
CH47_RS06310	COG2372	response to copper ion
CH47_RS06315	COG1276	copper resistance
CH47_RS06325	COG4974	Belongs to the 'phage' integrase family
CH47_RS06380	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH47_RS06425	COG3077	Addiction module antitoxin, RelB DinJ family
CH47_RS06430	COG3041	Addiction module toxin RelE StbE family
CH47_RS06525	COG4695	Portal protein
CH47_RS06550	COG2963	transposase activity
CH47_RS06555	COG2801	Transposase and inactivated derivatives
CH47_RS06600	COG2801	Transposase and inactivated derivatives
CH47_RS06605	COG2963	transposase activity
CH47_RS06635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH47_RS06640	COG0322	excinuclease ABC activity
CH47_RS06645	COG2197	response regulator
CH47_RS06655	COG3136	membrane protein required for alginate biosynthesis
CH47_RS06695	COG3772	lysozyme
CH47_RS06700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CH47_RS06705	COG1187	pseudouridine synthase activity
CH47_RS06710	COG0786	glutamate:sodium symporter activity
CH47_RS06710	COG0786	glutamate:sodium symporter activity
CH47_RS06730	COG0668	transmembrane transport
CH47_RS06735	COG0625	glutathione transferase activity
CH47_RS06760	COG4251	negative regulation of phosphorylation
CH47_RS06760	COG3706	GGDEF domain
CH47_RS06760	COG2203	Gaf domain
CH47_RS06760	COG5001	Diguanylate cyclase
CH47_RS06795	COG2814	Major facilitator Superfamily
CH47_RS06805	COG3008	intermembrane lipid transfer
CH47_RS06810	COG2995	paraquat-inducible protein a
CH47_RS06815	COG1956	GAF domain-containing protein
CH47_RS06825	COG0793	Belongs to the peptidase S41A family
CH47_RS06830	COG0501	Belongs to the peptidase M48B family
CH47_RS06860	COG2814	Major facilitator Superfamily
CH47_RS06865	COG0823	Involved in the tonB-independent uptake of proteins
CH47_RS06875	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH47_RS06880	COG1823	symporter activity
CH47_RS06885	COG1988	membrane-bound metal-dependent
CH47_RS06890	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH47_RS06895	COG1653	transport
CH47_RS06900	COG3842	ATPase activity
CH47_RS06905	COG0395	ABC-type sugar transport system, permease component
CH47_RS06910	COG1175	transmembrane transport
CH47_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS06925	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CH47_RS06930	COG1917	Cupin 2, conserved barrel domain protein
CH47_RS06935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH47_RS06950	COG0583	DNA-binding transcription factor activity
CH47_RS06955	COG0427	acetyl-CoA hydrolase
CH47_RS06960	COG1024	Enoyl-CoA hydratase
CH47_RS06965	COG1703	isobutyryl-CoA mutase activity
CH47_RS06970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CH47_RS06970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CH47_RS06975	COG3001	Fructosamine kinase
CH47_RS06980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH47_RS06985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH47_RS06990	COG1121	(ABC) transporter
CH47_RS06995	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH47_RS07035	COG4249	Peptidase C14 caspase catalytic subunit p20
CH47_RS07040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CH47_RS07045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CH47_RS07050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CH47_RS07055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CH47_RS07060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CH47_RS07070	COG0776	regulation of translation
CH47_RS07075	COG2963	transposase activity
CH47_RS07090	COG1487	ribonuclease activity
CH47_RS07115	COG2314	TM2 domain
CH47_RS07120	COG0506	proline dehydrogenase activity
CH47_RS07120	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH47_RS07120	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH47_RS07140	COG3157	Type VI secretion system effector, Hcp
CH47_RS07150	COG0672	)-iron permease
CH47_RS07155	COG2822	iron ion transport
CH47_RS07165	COG0655	NAD(P)H dehydrogenase (quinone) activity
CH47_RS07175	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CH47_RS07180	COG2233	PERMEase
CH47_RS07185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH47_RS07190	COG0778	Nitroreductase
CH47_RS07195	COG2267	carboxylic ester hydrolase activity
CH47_RS07200	COG0251	oxidation-reduction process
CH47_RS07205	COG1335	isochorismatase
CH47_RS07210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH47_RS07215	COG1309	transcriptional regulator
CH47_RS07220	COG1113	amino acid transport
CH47_RS07265	COG2226	methyltransferase
CH47_RS07280	COG0366	Alpha amylase catalytic
CH47_RS07300	COG0671	phosphoesterase, PA-phosphatase related
CH47_RS07305	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH47_RS07310	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH47_RS07320	COG1396	sequence-specific DNA binding
CH47_RS07325	COG3135	benzoate transporter
CH47_RS07335	COG0284	orotidine-5'-phosphate decarboxylase activity
CH47_RS07340	COG0023	Translation Initiation Factor
CH47_RS07350	COG0235	Class ii aldolase
CH47_RS07360	COG1349	DNA-binding transcription factor activity
CH47_RS07365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH47_RS07370	COG2879	small protein
CH47_RS07375	COG1966	Carbon starvation protein
CH47_RS07380	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CH47_RS07385	COG0243	molybdopterin cofactor binding
CH47_RS07405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH47_RS07415	COG4659	FMN binding
CH47_RS07420	COG4658	electron transport chain
CH47_RS07425	COG2207	Transcriptional regulator
CH47_RS07425	COG3708	Transcriptional regulator
CH47_RS07430	COG4656	Part of a membrane complex involved in electron transport
CH47_RS07440	COG4657	Part of a membrane complex involved in electron transport
CH47_RS07450	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CH47_RS07470	COG2160	L-arabinose isomerase activity
CH47_RS07480	COG1879	ABC-type sugar transport system periplasmic component
CH47_RS07485	COG1129	ABC transporter
CH47_RS07490	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS07500	COG0673	inositol 2-dehydrogenase activity
CH47_RS07505	COG0385	Bile acid
CH47_RS07510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CH47_RS07515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH47_RS07520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS07520	COG1263	PTS System
CH47_RS07525	COG1609	Transcriptional regulator
CH47_RS07535	COG5339	Protein conserved in bacteria
CH47_RS07545	COG0114	fumarate hydratase activity
CH47_RS07570	COG2814	Major facilitator Superfamily
CH47_RS07575	COG0583	DNA-binding transcription factor activity
CH47_RS07580	COG1940	carbohydrate kinase activity
CH47_RS07585	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH47_RS07610	COG1742	UPF0060 membrane protein
CH47_RS07615	COG4221	oxidoreductase activity
CH47_RS07620	COG0477	Major facilitator Superfamily
CH47_RS07660	COG0625	glutathione transferase activity
CH47_RS07670	COG1522	sequence-specific DNA binding
CH47_RS07695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH47_RS07715	COG0583	DNA-binding transcription factor activity
CH47_RS07720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH47_RS07730	COG0483	inositol monophosphate 1-phosphatase activity
CH47_RS07735	COG2271	Major facilitator Superfamily
CH47_RS07755	COG0028	Belongs to the TPP enzyme family
CH47_RS07760	COG0440	acetolactate synthase activity
CH47_RS07765	COG1011	Hydrolase
CH47_RS07785	COG0738	Major facilitator superfamily
CH47_RS07790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH47_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS07805	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CH47_RS07820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH47_RS07825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH47_RS07830	COG0589	response to stress
CH47_RS07835	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH47_RS07840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH47_RS07855	COG0531	amino acid
CH47_RS07865	COG0745	RESPONSE REGULATOR receiver
CH47_RS07870	COG2205	protein histidine kinase activity
CH47_RS07875	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH47_RS07885	COG3591	Belongs to the peptidase S1B family
CH47_RS07900	COG1643	Atp-dependent helicase
CH47_RS07910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CH47_RS07920	COG3784	Protein of unknown function (DUF1318)
CH47_RS07930	COG2911	Protein conserved in bacteria
CH47_RS07935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH47_RS07940	COG3042	response to heat
CH47_RS07945	COG1285	pathogenesis
CH47_RS07955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS07955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH47_RS07955	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH47_RS07955	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH47_RS07960	COG2723	6-phospho-beta-galactosidase activity
CH47_RS07965	COG2190	(PTS) system
CH47_RS07965	COG1263	PTS System
CH47_RS07965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS07970	COG3711	transcriptional antiterminator
CH47_RS07975	COG0037	tRNA processing
CH47_RS07980	COG0598	Magnesium transport protein CorA
CH47_RS07995	COG4166	transmembrane transport
CH47_RS08000	COG2866	Carboxypeptidase
CH47_RS08005	COG4948	Mandelate Racemase Muconate Lactonizing
CH47_RS08010	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH47_RS08020	COG5642	Protein of unknown function (DUF2384)
CH47_RS08025	COG5654	RES domain protein
CH47_RS08030	COG3768	UPF0283 membrane protein
CH47_RS08035	COG3106	COG3106 Predicted ATPase
CH47_RS08045	COG1983	PspC domain protein
CH47_RS08055	COG1842	Phage shock protein A
CH47_RS08060	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH47_RS08075	COG4166	transmembrane transport
CH47_RS08080	COG4168	peptide transport system, permease
CH47_RS08085	COG4171	peptide transport system, permease
CH47_RS08095	COG4172	Belongs to the ABC transporter superfamily
CH47_RS08105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH47_RS08105	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH47_RS08115	COG3104	oligopeptide transport
CH47_RS08135	COG0625	glutathione transferase activity
CH47_RS08145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CH47_RS08150	COG0259	pyridoxamine-phosphate oxidase activity
CH47_RS08155	COG3895	Periplasmic Protein
CH47_RS08160	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CH47_RS08165	COG3133	Outer membrane lipoprotein
CH47_RS08170	COG1846	Transcriptional regulator
CH47_RS08180	COG1566	PFAM secretion protein HlyD family protein
CH47_RS08185	COG1289	transmembrane transporter activity
CH47_RS08190	COG4989	oxidoreductase activity
CH47_RS08195	COG3313	Fe-S protein
CH47_RS08200	COG2194	sulfuric ester hydrolase activity
CH47_RS08205	COG1309	transcriptional regulator
CH47_RS08210	COG1902	pentaerythritol trinitrate reductase activity
CH47_RS08215	COG0346	lactoylglutathione lyase activity
CH47_RS08220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH47_RS08225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH47_RS08230	COG0791	NLP P60 protein
CH47_RS08240	COG1609	Transcriptional regulator
CH47_RS08245	COG0583	DNA-binding transcription factor activity
CH47_RS08250	COG2814	Major facilitator Superfamily
CH47_RS08255	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH47_RS08260	COG0307	riboflavin synthase, alpha
CH47_RS08265	COG0534	Mate efflux family protein
CH47_RS08295	COG1376	ErfK ybiS ycfS ynhG family protein
CH47_RS08295	COG1388	LysM domain
CH47_RS08300	COG2166	iron-sulfur cluster assembly
CH47_RS08310	COG0719	Fe-S assembly protein
CH47_RS08315	COG0396	ATPase activity
CH47_RS08320	COG0719	Fe-S assembly protein
CH47_RS08325	COG0316	Belongs to the HesB IscA family
CH47_RS08330	COG2050	protein possibly involved in aromatic compounds catabolism
CH47_RS08335	COG0277	FAD linked oxidase domain protein
CH47_RS08335	COG0247	lactate metabolic process
CH47_RS08340	COG0628	permease
CH47_RS08345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH47_RS08345	COG0574	Belongs to the PEP-utilizing enzyme family
CH47_RS08350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CH47_RS08365	COG4771	TonB-dependent receptor
CH47_RS08370	COG3720	iron ion transport
CH47_RS08375	COG4558	Periplasmic binding protein
CH47_RS08385	COG0095	Lipoate-protein ligase
CH47_RS08390	COG0791	NLP P60 protein
CH47_RS08395	COG2076	Multidrug Resistance protein
CH47_RS08400	COG2076	Multidrug Resistance protein
CH47_RS08405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CH47_RS08410	COG0726	polysaccharide deacetylase
CH47_RS08415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS08415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CH47_RS08420	COG0463	Glycosyl transferase, family 2
CH47_RS08425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH47_RS08430	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CH47_RS08435	COG0386	Belongs to the glutathione peroxidase family
CH47_RS08440	COG4139	cobalamin transport
CH47_RS08450	COG0583	DNA-binding transcription factor activity
CH47_RS08465	COG0616	signal peptide processing
CH47_RS08470	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS08475	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CH47_RS08480	COG1187	pseudouridine synthase activity
CH47_RS08485	COG0009	L-threonylcarbamoyladenylate synthase
CH47_RS08490	COG0613	PHP domain protein
CH47_RS08500	COG0512	Glutamine amidotransferase of anthranilate synthase
CH47_RS08510	COG0134	indole-3-glycerol-phosphate synthase activity
CH47_RS08510	COG0135	phosphoribosylanthranilate isomerase activity
CH47_RS08515	COG0133	tryptophan synthase activity
CH47_RS08520	COG0159	tryptophan synthase activity
CH47_RS08530	COG3047	cAMP biosynthetic process
CH47_RS08535	COG0727	PFAM Uncharacterised protein family (UPF0153)
CH47_RS08550	COG2917	probably involved in intracellular septation
CH47_RS08555	COG1607	acyl-coa hydrolase
CH47_RS08560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH47_RS08565	COG2350	Protein conserved in bacteria
CH47_RS08580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH47_RS08585	COG3099	Belongs to the UPF0263 family
CH47_RS08595	COG0444	Belongs to the ABC transporter superfamily
CH47_RS08600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH47_RS08620	COG2095	MarC family integral membrane protein
CH47_RS08625	COG1454	alcohol dehydrogenase
CH47_RS08625	COG1012	belongs to the aldehyde dehydrogenase family
CH47_RS08640	COG2916	Histone family protein nucleoid-structuring protein H-NS
CH47_RS08650	COG0745	RESPONSE REGULATOR receiver
CH47_RS08655	COG1752	Esterase of the alpha-beta hydrolase superfamily
CH47_RS08665	COG3012	SEC-C Motif Domain Protein
CH47_RS08670	COG0788	formyltetrahydrofolate deformylase activity
CH47_RS08685	COG0583	DNA-binding transcription factor activity
CH47_RS08690	COG0708	Exodeoxyribonuclease III
CH47_RS08695	COG0494	nUDIX hydrolase
CH47_RS08705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH47_RS08715	COG0778	Nitroreductase
CH47_RS08720	COG0616	signal peptide processing
CH47_RS08725	COG0252	asparaginase activity
CH47_RS08730	COG1335	isochorismatase
CH47_RS08735	COG3139	Protein of unknown function (DUF1315)
CH47_RS08740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH47_RS08770	COG3713	MltA-interacting MipA family protein
CH47_RS08775	COG2766	serine protein kinase
CH47_RS08780	COG2718	Belongs to the UPF0229 family
CH47_RS08795	COG0583	DNA-binding transcription factor activity
CH47_RS08805	COG2202	Pas domain
CH47_RS08805	COG2200	EAL domain
CH47_RS08805	COG2199	diguanylate cyclase activity
CH47_RS08810	COG2814	Major facilitator Superfamily
CH47_RS08815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH47_RS08820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CH47_RS08825	COG2719	SpoVR family
CH47_RS08830	COG2186	Transcriptional regulator
CH47_RS08835	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CH47_RS08840	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CH47_RS08845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH47_RS08880	COG0582	viral genome integration into host DNA
CH47_RS08885	COG2983	Belongs to the UPF0260 family
CH47_RS08890	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH47_RS08895	COG2951	lytic endotransglycosylase activity
CH47_RS08900	COG3100	YcgL domain-containing protein
CH47_RS08910	COG0850	regulation of cytokinetic process
CH47_RS08915	COG2894	cell division
CH47_RS08920	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH47_RS08925	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH47_RS08930	COG0318	PFAM AMP-dependent synthetase and ligase
CH47_RS08935	COG3065	identical protein binding
CH47_RS08945	COG1199	ATP-dependent helicase activity
CH47_RS08950	COG0251	oxidation-reduction process
CH47_RS08955	COG2076	Multidrug Resistance protein
CH47_RS08960	COG2076	Multidrug Resistance protein
CH47_RS08965	COG0800	Aldolase
CH47_RS08970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH47_RS08975	COG1737	Transcriptional regulator
CH47_RS08980	COG0469	pyruvate kinase activity
CH47_RS08985	COG1560	Kdo2-lipid A biosynthetic process
CH47_RS08990	COG0739	heme binding
CH47_RS08995	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH47_RS09000	COG1121	(ABC) transporter
CH47_RS09005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH47_RS09010	COG3104	oligopeptide transport
CH47_RS09015	COG2255	four-way junction helicase activity
CH47_RS09020	COG0632	four-way junction helicase activity
CH47_RS09025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CH47_RS09030	COG0217	transcriptional regulatory protein
CH47_RS09035	COG0494	nUDIX hydrolase
CH47_RS09040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CH47_RS09045	COG1335	isochorismatase
CH47_RS09050	COG1801	Protein of unknown function DUF72
CH47_RS09055	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH47_RS09060	COG2226	methyltransferase
CH47_RS09065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH47_RS09070	COG3142	Participates in the control of copper homeostasis
CH47_RS09075	COG3102	Protein conserved in bacteria
CH47_RS09080	COG0018	arginyl-trna synthetase
CH47_RS09095	COG0728	peptidoglycan biosynthetic process
CH47_RS09100	COG0673	inositol 2-dehydrogenase activity
CH47_RS09110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH47_RS09125	COG0477	Major facilitator Superfamily
CH47_RS09135	COG3381	protein complex oligomerization
CH47_RS09140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CH47_RS09145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH47_RS09165	COG3706	GGDEF domain
CH47_RS09170	COG0659	secondary active sulfate transmembrane transporter activity
CH47_RS09175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CH47_RS09190	COG2890	protein-(glutamine-N5) methyltransferase activity
CH47_RS09195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CH47_RS09200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CH47_RS09205	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CH47_RS09215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH47_RS09225	COG0193	aminoacyl-tRNA hydrolase activity
CH47_RS09235	COG0012	GTP binding
CH47_RS09250	COG2979	Protein of unknown function (DUF533)
CH47_RS09285	COG1349	DNA-binding transcription factor activity
CH47_RS09300	COG4942	peptidase
CH47_RS09320	COG3443	Belongs to the bacterial solute-binding protein 9 family
CH47_RS09330	COG0402	S-adenosylhomocysteine deaminase activity
CH47_RS09340	COG1228	amidohydrolase
CH47_RS09355	COG2988	succinylglutamate desuccinylase activity
CH47_RS09360	COG3724	N-succinylarginine dihydrolase activity
CH47_RS09370	COG3138	arginine N-succinyltransferase
CH47_RS09375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CH47_RS09380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH47_RS09385	COG1271	oxidase subunit
CH47_RS09390	COG1294	oxidase, subunit
CH47_RS09395	COG3850	Histidine kinase
CH47_RS09400	COG0583	DNA-binding transcription factor activity
CH47_RS09405	COG2814	Major facilitator Superfamily
CH47_RS09415	COG0387	Pfam Sodium calcium exchanger
CH47_RS09420	COG1702	phosphate starvation-inducible protein PhoH
CH47_RS09435	COG3658	cytochrome
CH47_RS09440	COG1215	transferase activity, transferring glycosyl groups
CH47_RS09445	COG1649	PFAM Uncharacterised BCR, COG1649
CH47_RS09445	COG0726	polysaccharide deacetylase
CH47_RS09450	COG0457	Tetratricopeptide repeat
CH47_RS09455	COG0006	proline dipeptidase activity
CH47_RS09460	COG4114	ferric iron reductase
CH47_RS09465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH47_RS09490	COG0577	efflux transmembrane transporter activity
CH47_RS09490	COG1136	(ABC) transporter
CH47_RS09500	COG0577	efflux transmembrane transporter activity
CH47_RS09500	COG1136	(ABC) transporter
CH47_RS09515	COG0672	)-iron permease
CH47_RS09530	COG2066	Belongs to the glutaminase family
CH47_RS09535	COG3622	Belongs to the hyi family
CH47_RS09540	COG0235	Class ii aldolase
CH47_RS09545	COG3395	kinase activity
CH47_RS09550	COG1349	DNA-binding transcription factor activity
CH47_RS09555	COG3290	protein histidine kinase activity
CH47_RS09560	COG4565	transcriptional regulatory protein
CH47_RS09565	COG3493	citrate carrier protein
CH47_RS09590	COG2223	nitrite transmembrane transporter activity
CH47_RS09595	COG0561	phosphatase activity
CH47_RS09600	COG1126	abc transporter atp-binding protein
CH47_RS09605	COG0765	amino acid transport
CH47_RS09610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS09615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CH47_RS09625	COG1191	sigma factor activity
CH47_RS09670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH47_RS09675	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH47_RS09700	COG2801	Transposase and inactivated derivatives
CH47_RS09705	COG1677	Flagellar hook-basal body complex protein FliE
CH47_RS09720	COG1317	bacterial-type flagellum organization
CH47_RS09740	COG1580	Controls the rotational direction of flagella during chemotaxis
CH47_RS09760	COG1338	Plays a role in the flagellum-specific transport system
CH47_RS09780	COG1256	bacterial-type flagellum assembly
CH47_RS09815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH47_RS09820	COG1558	bacterial-type flagellum-dependent cell motility
CH47_RS09825	COG1815	bacterial-type flagellum-dependent cell motility
CH47_RS09835	COG2747	anti-sigma28 factor FlgM
CH47_RS09840	COG3418	PFAM FlgN family protein
CH47_RS09855	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH47_RS09860	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH47_RS09865	COG1404	Belongs to the peptidase S8 family
CH47_RS09865	COG4935	Belongs to the peptidase S8 family
CH47_RS09870	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH47_RS09875	COG0745	RESPONSE REGULATOR receiver
CH47_RS09885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH47_RS09890	COG0840	transmembrane signaling receptor activity
CH47_RS09895	COG0840	transmembrane signaling receptor activity
CH47_RS09900	COG0835	chemotaxis
CH47_RS09905	COG2198	Histidine kinase
CH47_RS09905	COG0643	Histidine kinase
CH47_RS09910	COG1360	Flagellar Motor Protein
CH47_RS09930	COG0589	response to stress
CH47_RS09935	COG2130	NADP-dependent
CH47_RS09945	COG1285	pathogenesis
CH47_RS09955	COG0840	transmembrane signaling receptor activity
CH47_RS09970	COG1609	Transcriptional regulator
CH47_RS09975	COG3250	beta-galactosidase activity
CH47_RS09985	COG3385	transposase activity
CH47_RS09990	COG3321	synthase
CH47_RS09990	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS09990	COG0604	alcohol dehydrogenase
CH47_RS10020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CH47_RS10025	COG3121	Chaperone
CH47_RS10030	COG1070	Carbohydrate kinase
CH47_RS10035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH47_RS10045	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS10050	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS10055	COG1129	ABC transporter
CH47_RS10065	COG3228	Belongs to the MtfA family
CH47_RS10080	COG1169	isochorismate synthase
CH47_RS10085	COG2814	Major facilitator Superfamily
CH47_RS10090	COG1132	(ABC) transporter
CH47_RS10105	COG2226	methyltransferase
CH47_RS10105	COG3433	isochorismatase activity
CH47_RS10105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH47_RS10125	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH47_RS10150	COG2801	Transposase and inactivated derivatives
CH47_RS10160	COG2801	Transposase and inactivated derivatives
CH47_RS10165	COG2963	transposase activity
CH47_RS10180	COG1204	response to ionizing radiation
CH47_RS10205	COG3122	Protein conserved in bacteria
CH47_RS10215	COG2814	Major facilitator Superfamily
CH47_RS10235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH47_RS10250	COG0471	metal ion transport
CH47_RS10265	COG3051	citrate lyase alpha subunit
CH47_RS10270	COG2301	Belongs to the HpcH HpaI aldolase family
CH47_RS10275	COG3052	prosthetic group binding
CH47_RS10280	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CH47_RS10285	COG3290	protein histidine kinase activity
CH47_RS10290	COG4565	transcriptional regulatory protein
CH47_RS10305	COG2271	Major facilitator Superfamily
CH47_RS10310	COG1840	ABC-type Fe3 transport system, periplasmic component
CH47_RS10320	COG3842	ATPase activity
CH47_RS10335	COG2205	protein histidine kinase activity
CH47_RS10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS10360	COG3121	Chaperone
CH47_RS10395	COG0784	Response regulator, receiver
CH47_RS10395	COG0835	chemotaxis
CH47_RS10405	COG1349	DNA-binding transcription factor activity
CH47_RS10410	COG0561	phosphatase activity
CH47_RS10415	COG0352	thiamine-phosphate diphosphorylase activity
CH47_RS10425	COG0534	Mate efflux family protein
CH47_RS10430	COG0137	argininosuccinate synthase activity
CH47_RS10500	COG3188	usher protein
CH47_RS10505	COG3121	Chaperone
CH47_RS10565	COG2211	Major facilitator Superfamily
CH47_RS10570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CH47_RS10590	COG1492	cobalamin metabolic process
CH47_RS10655	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CH47_RS10665	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CH47_RS10740	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CH47_RS10760	COG4656	Part of a membrane complex involved in electron transport
CH47_RS10780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH47_RS10785	COG1648	precorrin-2 dehydrogenase activity
CH47_RS10785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CH47_RS10790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CH47_RS10815	COG1129	ABC transporter
CH47_RS10820	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS10830	COG2926	Belongs to the UPF0265 family
CH47_RS10835	COG1289	transmembrane transporter activity
CH47_RS10840	COG1022	Amp-dependent synthetase and ligase
CH47_RS10840	COG3320	Male sterility
CH47_RS10845	COG2925	Exonuclease
CH47_RS10850	COG0531	amino acid
CH47_RS10860	COG0371	Dehydrogenase
CH47_RS10865	COG1129	ABC transporter
CH47_RS10870	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS10875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS10880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CH47_RS10890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CH47_RS10895	COG0131	Imidazoleglycerol-phosphate dehydratase
CH47_RS10895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH47_RS10905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CH47_RS10910	COG0107	imidazoleglycerol-phosphate synthase activity
CH47_RS10915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH47_RS10915	COG0140	phosphoribosyl-ATP diphosphatase activity
CH47_RS10920	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CH47_RS10925	COG3385	transposase activity
CH47_RS10930	COG3385	transposase activity
CH47_RS10935	COG3385	transposase activity
CH47_RS10940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH47_RS10945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH47_RS10950	COG1253	flavin adenine dinucleotide binding
CH47_RS10955	COG3069	C4-dicarboxylate transmembrane transporter activity
CH47_RS10960	COG2982	Protein involved in outer membrane biogenesis
CH47_RS10965	COG0717	Belongs to the dCTP deaminase family
CH47_RS10970	COG0572	uridine kinase
CH47_RS10975	COG0489	protein tyrosine kinase activity
CH47_RS10980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH47_RS10980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH47_RS11000	COG2814	Major facilitator Superfamily
CH47_RS11005	COG1380	Effector of murein hydrolase LrgA
CH47_RS11010	COG1346	cytolysis
CH47_RS11025	COG0281	malic enzyme
CH47_RS11030	COG2949	membrane
CH47_RS11035	COG0298	carbon dioxide binding
CH47_RS11040	COG0375	protein maturation
CH47_RS11045	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH47_RS11050	COG0651	ATP synthesis coupled electron transport
CH47_RS11055	COG0650	Formate hydrogenlyase subunit 4
CH47_RS11060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH47_RS11065	COG4237	Hydrogenase 4 membrane
CH47_RS11070	COG0651	ATP synthesis coupled electron transport
CH47_RS11075	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CH47_RS11075	COG3261	NADH dehydrogenase
CH47_RS11080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH47_RS11085	COG3260	NADH ubiquinone oxidoreductase 20
CH47_RS11095	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CH47_RS11100	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH47_RS11105	COG3383	formate dehydrogenase (NAD+) activity
CH47_RS11110	COG3604	Transcriptional regulator
CH47_RS11115	COG2116	formate transmembrane transporter activity
CH47_RS11140	COG2311	Membrane
CH47_RS11145	COG0302	gtp cyclohydrolase
CH47_RS11150	COG0477	Major facilitator Superfamily
CH47_RS11155	COG0583	DNA-binding transcription factor activity
CH47_RS11190	COG0577	efflux transmembrane transporter activity
CH47_RS11190	COG1136	(ABC) transporter
CH47_RS11205	COG0303	'Molybdopterin
CH47_RS11210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH47_RS11215	COG3397	chitin binding
CH47_RS11220	COG0488	(ABC) transporter
CH47_RS11240	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH47_RS11260	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CH47_RS11275	COG4106	trans-aconitate 2-methyltransferase activity
CH47_RS11280	COG0783	Belongs to the Dps family
CH47_RS11285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CH47_RS11290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS11295	COG0765	amino acid transport
CH47_RS11300	COG1126	abc transporter atp-binding protein
CH47_RS11310	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CH47_RS11330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH47_RS11335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH47_RS11355	COG0697	spore germination
CH47_RS11365	COG0583	DNA-binding transcription factor activity
CH47_RS11380	COG1174	glycine betaine transport
CH47_RS11385	COG1125	glycine betaine transport
CH47_RS11390	COG1174	glycine betaine transport
CH47_RS11395	COG1732	Glycine betaine
CH47_RS11410	COG2897	thiosulfate sulfurtransferase activity
CH47_RS11420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CH47_RS11440	COG4807	Protein conserved in bacteria
CH47_RS11455	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH47_RS11465	COG2261	transglycosylase associated protein
CH47_RS11485	COG0277	FAD linked oxidase domain protein
CH47_RS11490	COG1686	Belongs to the peptidase S11 family
CH47_RS11505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH47_RS11510	COG3385	transposase activity
CH47_RS11515	COG3385	transposase activity
CH47_RS11520	COG0513	Belongs to the DEAD box helicase family
CH47_RS11525	COG1309	transcriptional regulator
CH47_RS11530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS11535	COG1131	(ABC) transporter
CH47_RS11540	COG0842	Transport permease protein
CH47_RS11545	COG0842	Transport permease protein
CH47_RS11550	COG0670	Belongs to the BI1 family
CH47_RS11555	COG0314	molybdopterin synthase activity
CH47_RS11560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH47_RS11565	COG0315	cyclic pyranopterin monophosphate synthase activity
CH47_RS11570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH47_RS11575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH47_RS11580	COG4628	conserved protein (DUF2132)
CH47_RS11585	COG0556	nucleotide-excision repair
CH47_RS11600	COG2226	methyltransferase
CH47_RS11605	COG0156	8-amino-7-oxononanoate synthase activity
CH47_RS11610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CH47_RS11620	COG2706	6-phosphogluconolactonase activity
CH47_RS11625	COG0561	phosphatase activity
CH47_RS11635	COG4149	molybdate abc transporter
CH47_RS11640	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH47_RS11650	COG3585	molybdate ion transport
CH47_RS11650	COG2005	Transcriptional regulator
CH47_RS11655	COG1119	ATPase activity
CH47_RS11665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH47_RS11670	COG1085	galactose-1-phosphate uridylyltransferase
CH47_RS11675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CH47_RS11680	COG2017	converts alpha-aldose to the beta-anomer
CH47_RS11700	COG0588	phosphoglycerate mutase activity
CH47_RS11705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH47_RS11710	COG1230	cation diffusion facilitator family transporter
CH47_RS11720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CH47_RS11745	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH47_RS11750	COG2885	chlorophyll binding
CH47_RS11755	COG0823	Involved in the tonB-independent uptake of proteins
CH47_RS11760	COG3064	Membrane
CH47_RS11760	COG3064	Membrane
CH47_RS11765	COG0848	biopolymer transport protein
CH47_RS11770	COG0811	peptide transport
CH47_RS11775	COG0824	Thioesterase
CH47_RS11780	COG3790	cyd operon protein YbgE
CH47_RS11785	COG4890	Cyd operon protein YbgT
CH47_RS11790	COG1294	oxidase, subunit
CH47_RS11795	COG1271	oxidase subunit
CH47_RS11800	COG0737	Belongs to the 5'-nucleotidase family
CH47_RS11805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH47_RS11810	COG0045	succinate-CoA ligase (ADP-forming) activity
CH47_RS11815	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH47_RS11820	COG0567	Dehydrogenase, E1 component
CH47_RS11830	COG1053	succinate dehydrogenase
CH47_RS11835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH47_RS11840	COG2009	succinate dehydrogenase
CH47_RS11850	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CH47_RS11865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CH47_RS11870	COG1984	allophanate hydrolase subunit 2
CH47_RS11875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CH47_RS11880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH47_RS11885	COG5212	phosphodiesterase
CH47_RS11895	COG3272	Protein of unknown function (DUF1722)
CH47_RS11910	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CH47_RS11915	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CH47_RS11920	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CH47_RS11925	COG2205	protein histidine kinase activity
CH47_RS11930	COG0745	RESPONSE REGULATOR receiver
CH47_RS11945	COG0033	Phosphoglucomutase
CH47_RS11950	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH47_RS11955	COG0596	Alpha beta hydrolase
CH47_RS11965	COG0840	transmembrane signaling receptor activity
CH47_RS11975	COG0735	belongs to the Fur family
CH47_RS11995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH47_RS12000	COG1263	PTS System
CH47_RS12000	COG2190	(PTS) system
CH47_RS12000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS12005	COG0363	glucosamine-6-phosphate deaminase activity
CH47_RS12010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH47_RS12015	COG1940	carbohydrate kinase activity
CH47_RS12015	COG1846	Transcriptional regulator
CH47_RS12020	COG0647	UMP catabolic process
CH47_RS12025	COG0367	asparagine synthase
CH47_RS12060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH47_RS12065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH47_RS12070	COG1702	phosphate starvation-inducible protein PhoH
CH47_RS12075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CH47_RS12080	COG4535	Mg2 and Co2 transporter CorC
CH47_RS12085	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH47_RS12100	COG0765	amino acid transport
CH47_RS12105	COG0765	amino acid transport
CH47_RS12110	COG1126	abc transporter atp-binding protein
CH47_RS12115	COG2888	peptidyl-tyrosine sulfation
CH47_RS12120	COG0495	leucyl-tRNA aminoacylation
CH47_RS12125	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CH47_RS12130	COG1466	dna polymerase III delta subunit
CH47_RS12135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CH47_RS12140	COG0799	negative regulation of ribosome biogenesis
CH47_RS12150	COG0768	penicillin binding
CH47_RS12155	COG0772	Belongs to the SEDS family
CH47_RS12160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH47_RS12165	COG1686	Belongs to the peptidase S11 family
CH47_RS12170	COG2921	Belongs to the UPF0250 family
CH47_RS12175	COG0321	lipoyl(octanoyl) transferase activity
CH47_RS12180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CH47_RS12185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH47_RS12190	COG3706	GGDEF domain
CH47_RS12205	COG1278	Cold shock
CH47_RS12210	COG2197	response regulator
CH47_RS12220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CH47_RS12235	COG5265	(ABC) transporter
CH47_RS12245	COG2986	histidine ammonia-lyase
CH47_RS12250	COG2850	peptidyl-arginine hydroxylation
CH47_RS12265	COG5002	protein histidine kinase activity
CH47_RS12285	COG0656	L-ascorbic acid biosynthetic process
CH47_RS12300	COG1902	pentaerythritol trinitrate reductase activity
CH47_RS12345	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH47_RS12350	COG1216	Glycosyl transferase, family 2
CH47_RS12360	COG5301	cellulose 1,4-beta-cellobiosidase activity
CH47_RS12395	COG0582	viral genome integration into host DNA
CH47_RS12405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CH47_RS12410	COG2501	S4 domain
CH47_RS12415	COG0215	cysteine-tRNA ligase activity
CH47_RS12420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH47_RS12425	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH47_RS12430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH47_RS12435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH47_RS12440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH47_RS12445	COG4181	ATPase activity
CH47_RS12450	COG2755	lipolytic protein G-D-S-L family
CH47_RS12455	COG0300	oxidoreductase activity
CH47_RS12460	COG3118	belongs to the thioredoxin family
CH47_RS12465	COG0330	HflC and HflK could
CH47_RS12470	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH47_RS12475	COG0789	Transcriptional regulator
CH47_RS12480	COG2217	Heavy metal translocating P-type atpase
CH47_RS12485	COG3735	TraB family
CH47_RS12490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH47_RS12500	COG0737	Belongs to the 5'-nucleotidase family
CH47_RS12505	COG2223	nitrite transmembrane transporter activity
CH47_RS12510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH47_RS12510	COG4651	solute:proton antiporter activity
CH47_RS12515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH47_RS12530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CH47_RS12540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS12545	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CH47_RS12550	COG0438	transferase activity, transferring glycosyl groups
CH47_RS12560	COG1216	Glycosyl transferase, family 2
CH47_RS12590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS12605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CH47_RS12610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CH47_RS12615	COG0563	adenylate kinase activity
CH47_RS12620	COG0326	Molecular chaperone. Has ATPase activity
CH47_RS12625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CH47_RS12630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CH47_RS12640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CH47_RS12645	COG2832	Protein of unknown function (DUF454)
CH47_RS12660	COG3264	Mechanosensitive ion channel
CH47_RS12660	COG1196	nuclear chromosome segregation
CH47_RS12665	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH47_RS12670	COG1309	transcriptional regulator
CH47_RS12675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS12680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH47_RS12690	COG3457	Alanine racemase
CH47_RS12695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CH47_RS12710	COG0254	rRNA binding
CH47_RS12715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH47_RS12720	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH47_RS12725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH47_RS12750	COG3695	enzyme binding
CH47_RS12755	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH47_RS12760	COG1946	Acyl-CoA thioesterase
CH47_RS12765	COG0004	ammonium transporteR
CH47_RS12770	COG0347	Belongs to the P(II) protein family
CH47_RS12775	COG1132	(ABC) transporter
CH47_RS12780	COG1132	(ABC) transporter
CH47_RS12785	COG1522	sequence-specific DNA binding
CH47_RS12795	COG0561	phosphatase activity
CH47_RS12800	COG4533	DNA binding
CH47_RS12805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CH47_RS12810	COG0824	Thioesterase
CH47_RS12815	COG1555	photosystem II stabilization
CH47_RS12820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH47_RS12825	COG0776	regulation of translation
CH47_RS12830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH47_RS12835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CH47_RS12840	COG0740	serine-type endopeptidase activity
CH47_RS12845	COG0544	peptidyl-prolyl cis-trans isomerase activity
CH47_RS12850	COG0271	Belongs to the BolA IbaG family
CH47_RS12855	COG3056	Lipoprotein
CH47_RS12860	COG2223	nitrite transmembrane transporter activity
CH47_RS12870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH47_RS12875	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH47_RS12880	COG1845	cytochrome c oxidase, subunit III
CH47_RS12885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH47_RS12890	COG0109	protoheme IX farnesyltransferase activity
CH47_RS12895	COG2814	Major facilitator Superfamily
CH47_RS12900	COG1666	GTP binding
CH47_RS12905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH47_RS12915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH47_RS12915	COG0301	tRNA thio-modification
CH47_RS12925	COG0142	geranyltranstransferase activity
CH47_RS12930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CH47_RS12935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH47_RS12940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH47_RS12945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH47_RS12950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CH47_RS12955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH47_RS12955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH47_RS12960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CH47_RS12965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH47_RS12970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH47_RS12975	COG1862	Preprotein translocase
CH47_RS12980	COG0343	queuine tRNA-ribosyltransferase activity
CH47_RS12990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CH47_RS12995	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CH47_RS13000	COG0450	alkyl hydroperoxide reductase
CH47_RS13015	COG0366	Alpha amylase catalytic
CH47_RS13035	COG5002	protein histidine kinase activity
CH47_RS13040	COG0745	RESPONSE REGULATOR receiver
CH47_RS13045	COG0420	3'-5' exonuclease activity
CH47_RS13050	COG0419	ATPase involved in DNA repair
CH47_RS13055	COG1940	carbohydrate kinase activity
CH47_RS13060	COG2974	May be involved in recombination
CH47_RS13065	COG3123	guanosine phosphorylase activity
CH47_RS13070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CH47_RS13095	COG2226	methyltransferase
CH47_RS13110	COG3459	Glycosyltransferase 36 associated
CH47_RS13120	COG1486	melibiose metabolic process
CH47_RS13130	COG2188	Transcriptional regulator
CH47_RS13135	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CH47_RS13140	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CH47_RS13150	COG1073	alpha beta
CH47_RS13155	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CH47_RS13160	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH47_RS13165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CH47_RS13180	COG2964	Protein conserved in bacteria
CH47_RS13185	COG1181	Belongs to the D-alanine--D-alanine ligase family
CH47_RS13195	COG2991	Protein conserved in bacteria
CH47_RS13200	COG1477	protein flavinylation
CH47_RS13205	COG2871	sodium ion transport
CH47_RS13210	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH47_RS13215	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH47_RS13220	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH47_RS13225	COG1805	sodium ion transport
CH47_RS13230	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH47_RS13235	COG3034	peptidoglycan biosynthetic process
CH47_RS13240	COG0121	glutamine amidotransferase
CH47_RS13245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CH47_RS13250	COG1960	acyl-CoA dehydrogenase activity
CH47_RS13255	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH47_RS13265	COG2831	hemolysin activation secretion protein
CH47_RS13270	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CH47_RS13275	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CH47_RS13280	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CH47_RS13285	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
CH47_RS13290	COG0235	Class ii aldolase
CH47_RS13295	COG0436	Aminotransferase
CH47_RS13305	COG2814	Major facilitator Superfamily
CH47_RS13310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH47_RS13320	COG1846	Transcriptional regulator
CH47_RS13325	COG1538	Outer membrane efflux protein
CH47_RS13330	COG1566	PFAM secretion protein HlyD family protein
CH47_RS13335	COG2814	Major facilitator Superfamily
CH47_RS13350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH47_RS13355	COG3118	belongs to the thioredoxin family
CH47_RS13360	COG3148	PFAM DTW domain containing protein
CH47_RS13365	COG1042	CoA-binding domain protein
CH47_RS13365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH47_RS13365	COG0045	succinate-CoA ligase (ADP-forming) activity
CH47_RS13370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH47_RS13375	COG2963	transposase activity
CH47_RS13380	COG2801	Transposase and inactivated derivatives
CH47_RS13385	COG5544	Lipoprotein
CH47_RS13390	COG3385	transposase activity
CH47_RS13395	COG3385	transposase activity
CH47_RS13420	COG0542	response to heat
CH47_RS13425	COG1496	oxidoreductase activity
CH47_RS13430	COG0564	pseudouridine synthase activity
CH47_RS13435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH47_RS13440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH47_RS13445	COG0077	Prephenate dehydratase
CH47_RS13445	COG1605	Chorismate mutase
CH47_RS13450	COG1605	Chorismate mutase
CH47_RS13450	COG0287	Prephenate dehydrogenase
CH47_RS13455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH47_RS13460	COG3279	Response regulator of the LytR AlgR family
CH47_RS13465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH47_RS13470	COG3137	Salt-induced outer membrane protein
CH47_RS13475	COG0335	large ribosomal subunit rRNA binding
CH47_RS13480	COG0336	Belongs to the RNA methyltransferase TrmD family
CH47_RS13485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CH47_RS13490	COG0228	four-way junction DNA binding
CH47_RS13495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH47_RS13500	COG4137	Cytochrome C assembly protein
CH47_RS13505	COG4536	flavin adenine dinucleotide binding
CH47_RS13510	COG1854	S-ribosylhomocysteine lyase activity
CH47_RS13515	COG2918	glutathione biosynthetic process
CH47_RS13520	COG1238	metal cluster binding
CH47_RS13525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH47_RS13550	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH47_RS13555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CH47_RS13560	COG2137	regulation of response to DNA damage stimulus
CH47_RS13565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CH47_RS13590	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH47_RS13595	COG3958	Transketolase
CH47_RS13600	COG3959	Transketolase, thiamine diphosphate binding domain
CH47_RS13605	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS13610	COG1129	ABC transporter
CH47_RS13620	COG1879	ABC-type sugar transport system periplasmic component
CH47_RS13630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH47_RS13630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH47_RS13665	COG0640	Transcriptional regulator
CH47_RS13670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CH47_RS13680	COG3665	Urea carboxylase-associated protein
CH47_RS13685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CH47_RS13690	COG1126	abc transporter atp-binding protein
CH47_RS13695	COG0765	amino acid transport
CH47_RS13700	COG0765	amino acid transport
CH47_RS13705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS13710	COG3048	D-serine ammonia-lyase activity
CH47_RS13725	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS13745	COG1538	Outer membrane efflux protein
CH47_RS13755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS13785	COG3539	Fimbrial protein
CH47_RS13790	COG3539	Fimbrial protein
CH47_RS13800	COG3121	Chaperone
CH47_RS13805	COG3188	usher protein
CH47_RS13830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CH47_RS13835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH47_RS13840	COG4942	peptidase
CH47_RS13840	COG1388	LysM domain
CH47_RS13845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CH47_RS13850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CH47_RS13855	COG0585	pseudouridine synthase activity
CH47_RS13860	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CH47_RS13870	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CH47_RS13880	COG0529	Catalyzes the synthesis of activated sulfate
CH47_RS13885	COG2895	sulfate adenylyltransferase (ATP) activity
CH47_RS13890	COG0175	sulfate reduction
CH47_RS13895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CH47_RS13895	COG1648	precorrin-2 dehydrogenase activity
CH47_RS13900	COG2234	aminopeptidase activity
CH47_RS13915	COG0175	sulfate reduction
CH47_RS13920	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH47_RS13925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CH47_RS13930	COG0720	synthase
CH47_RS13935	COG0602	queuosine metabolic process
CH47_RS13960	COG0148	phosphopyruvate hydratase activity
CH47_RS13965	COG0504	CTP synthase activity
CH47_RS13970	COG3956	TIGRFAM MazG family protein
CH47_RS13975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH47_RS13980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH47_RS13985	COG2205	protein histidine kinase activity
CH47_RS13985	COG3437	response regulator, receiver
CH47_RS13985	COG4999	Histidine kinase
CH47_RS13985	COG3850	Histidine kinase
CH47_RS13990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH47_RS13995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CH47_RS14000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH47_RS14010	COG2860	membrane
CH47_RS14015	COG0316	Belongs to the HesB IscA family
CH47_RS14025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CH47_RS14030	COG2223	nitrite transmembrane transporter activity
CH47_RS14040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH47_RS14045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH47_RS14050	COG1120	ATPase activity
CH47_RS14055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH47_RS14060	COG1643	Atp-dependent helicase
CH47_RS14065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH47_RS14070	COG1489	DNA binding
CH47_RS14090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH47_RS14095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CH47_RS14100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CH47_RS14105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CH47_RS14110	COG0726	polysaccharide deacetylase
CH47_RS14115	COG0842	Transport permease protein
CH47_RS14120	COG1131	(ABC) transporter
CH47_RS14125	COG0288	reversible hydration of carbon dioxide
CH47_RS14130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH47_RS14135	COG2132	Multicopper oxidase
CH47_RS14145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CH47_RS14150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CH47_RS14160	COG0697	spore germination
CH47_RS14165	COG3112	Uncharacterised protein family (UPF0231)
CH47_RS14185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH47_RS14190	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH47_RS14195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH47_RS14200	COG2186	Transcriptional regulator
CH47_RS14205	COG1113	amino acid transport
CH47_RS14215	COG3725	Membrane protein required for beta-lactamase induction
CH47_RS14230	COG4969	Belongs to the N-Me-Phe pilin family
CH47_RS14235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH47_RS14240	COG1459	type II secretion system
CH47_RS14245	COG0516	GMP reductase activity
CH47_RS14255	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CH47_RS14260	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CH47_RS14265	COG0494	nUDIX hydrolase
CH47_RS14270	COG0653	protein targeting
CH47_RS14290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH47_RS14295	COG0849	cell division
CH47_RS14300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH47_RS14310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH47_RS14315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CH47_RS14320	COG0772	Belongs to the SEDS family
CH47_RS14330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH47_RS14335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH47_RS14340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH47_RS14345	COG0768	penicillin binding
CH47_RS14350	COG3116	cell division
CH47_RS14355	COG0275	rRNA processing
CH47_RS14360	COG2001	Belongs to the MraZ family
CH47_RS14385	COG0028	Belongs to the TPP enzyme family
CH47_RS14390	COG1022	Amp-dependent synthetase and ligase
CH47_RS14400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CH47_RS14405	COG0473	3-isopropylmalate dehydrogenase activity
CH47_RS14410	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CH47_RS14425	COG3033	Beta-eliminating lyase
CH47_RS14430	COG0814	amino acid
CH47_RS14435	COG2814	Major facilitator Superfamily
CH47_RS14445	COG3077	Addiction module antitoxin, RelB DinJ family
CH47_RS14450	COG1882	Formate acetyltransferase
CH47_RS14455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH47_RS14460	COG4533	DNA binding
CH47_RS14475	COG4143	(ABC) transporter
CH47_RS14480	COG1178	ABC-type Fe3 transport system permease component
CH47_RS14490	COG0586	Pfam SNARE associated Golgi protein
CH47_RS14495	COG0417	DNA replication proofreading
CH47_RS14500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CH47_RS14505	COG0564	pseudouridine synthase activity
CH47_RS14510	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH47_RS14515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH47_RS14525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CH47_RS14530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CH47_RS14535	COG2967	ApaG domain
CH47_RS14540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CH47_RS14545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH47_RS14550	COG3610	response to peptide
CH47_RS14555	COG2966	Psort location CytoplasmicMembrane, score
CH47_RS14560	COG1280	lysine exporter protein (LysE YggA)
CH47_RS14565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH47_RS14575	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CH47_RS14580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CH47_RS14585	COG1047	Peptidyl-prolyl cis-trans
CH47_RS14590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CH47_RS14595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CH47_RS14600	COG0196	riboflavin kinase activity
CH47_RS14605	COG0268	Binds directly to 16S ribosomal RNA
CH47_RS14610	COG0583	DNA-binding transcription factor activity
CH47_RS14615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CH47_RS14620	COG0484	heat shock protein binding
CH47_RS14630	COG1584	GPR1 FUN34 yaaH family protein
CH47_RS14645	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH47_RS14650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH47_RS14655	COG3022	response to hydroperoxide
CH47_RS14665	COG0083	homoserine kinase activity
CH47_RS14680	COG0745	RESPONSE REGULATOR receiver
CH47_RS14685	COG3045	CreA protein
CH47_RS14690	COG3708	Transcriptional regulator
CH47_RS14690	COG2207	Transcriptional regulator
CH47_RS14695	COG0406	alpha-ribazole phosphatase activity
CH47_RS14700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CH47_RS14705	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH47_RS14710	COG0741	lytic transglycosylase activity
CH47_RS14715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CH47_RS14725	COG2199	diguanylate cyclase activity
CH47_RS14730	COG2885	chlorophyll binding
CH47_RS14735	COG0488	(ABC) transporter
CH47_RS14750	COG0604	alcohol dehydrogenase
CH47_RS14765	COG0560	Phosphoserine phosphatase
CH47_RS14770	COG3726	membrane protein affecting hemolysin expression
CH47_RS14775	COG3550	peptidyl-serine autophosphorylation
CH47_RS14780	COG0813	purine-nucleoside phosphorylase activity
CH47_RS14785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CH47_RS14790	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CH47_RS14800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH47_RS14805	COG0084	hydrolase, TatD family'
CH47_RS14810	COG4667	esterase of the alpha-beta hydrolase superfamily
CH47_RS14815	COG2823	Periplasmic or secreted lipoprotein
CH47_RS14820	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CH47_RS14825	COG0456	acetyltransferase
CH47_RS14830	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH47_RS14835	COG2813	Specifically methylates the guanine in position
CH47_RS14840	COG0667	Aldo Keto reductase
CH47_RS14845	COG0583	DNA-binding transcription factor activity
CH47_RS14870	COG4772	TonB-dependent receptor
CH47_RS14905	COG3284	Transcriptional regulator
CH47_RS14935	COG2192	nodulation
CH47_RS14945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS14945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH47_RS14945	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CH47_RS14950	COG1461	Dihydroxyacetone kinase
CH47_RS14955	COG2376	Dihydroxyacetone kinase
CH47_RS14965	COG3385	transposase activity
CH47_RS14970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH47_RS14975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS14980	COG2235	arginine
CH47_RS14995	COG0859	PFAM glycosyl transferase family 9
CH47_RS15000	COG1070	Carbohydrate kinase
CH47_RS15005	COG2390	Transcriptional regulator
CH47_RS15010	COG1129	ABC transporter
CH47_RS15015	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS15020	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS15025	COG1879	ABC-type sugar transport system periplasmic component
CH47_RS15030	COG1830	Aldolase
CH47_RS15035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH47_RS15110	COG0454	-acetyltransferase
CH47_RS15130	COG3077	Addiction module antitoxin, RelB DinJ family
CH47_RS15160	COG0795	lipopolysaccharide-transporting ATPase activity
CH47_RS15165	COG0795	lipopolysaccharide-transporting ATPase activity
CH47_RS15170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CH47_RS15175	COG2927	DNA polymerase III (CHI subunit)
CH47_RS15190	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH47_RS15200	COG2731	YhcH YjgK YiaL family protein
CH47_RS15210	COG0601	transmembrane transport
CH47_RS15215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH47_RS15220	COG0444	Belongs to the ABC transporter superfamily
CH47_RS15225	COG4608	Belongs to the ABC transporter superfamily
CH47_RS15240	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH47_RS15245	COG0583	DNA-binding transcription factor activity
CH47_RS15270	COG2188	Transcriptional regulator
CH47_RS15275	COG3624	Phosphonate C-P lyase system protein PhnG
CH47_RS15280	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH47_RS15285	COG3626	phosphonate metabolism
CH47_RS15290	COG3627	carbon phosphorus lyase activity
CH47_RS15295	COG4107	phosphonate C-P lyase system protein PhnK
CH47_RS15300	COG4778	phosphonate C-P lyase system protein PhnL
CH47_RS15305	COG3454	Phosphonate metabolism
CH47_RS15310	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH47_RS15315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH47_RS15320	COG0702	epimerase
CH47_RS15330	COG3787	Belongs to the UPF0306 family
CH47_RS15340	COG3842	ATPase activity
CH47_RS15345	COG0395	ABC-type sugar transport system, permease component
CH47_RS15350	COG1175	transmembrane transport
CH47_RS15355	COG1653	transport
CH47_RS15370	COG1982	Orn Lys Arg decarboxylase major
CH47_RS15375	COG0531	amino acid
CH47_RS15380	COG2827	Endonuclease containing a URI domain
CH47_RS15385	COG3153	acetyltransferase
CH47_RS15390	COG3154	lipid carrier protein
CH47_RS15395	COG0826	peptidase U32
CH47_RS15400	COG0826	peptidase U32
CH47_RS15405	COG3681	Belongs to the UPF0597 family
CH47_RS15410	COG0814	amino acid
CH47_RS15420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH47_RS15425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS15430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH47_RS15440	COG0513	Belongs to the DEAD box helicase family
CH47_RS15450	COG1185	polyribonucleotide nucleotidyltransferase activity
CH47_RS15455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CH47_RS15460	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CH47_RS15465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CH47_RS15475	COG0195	Participates in both transcription termination and antitermination
CH47_RS15480	COG0779	Required for maturation of 30S ribosomal subunits
CH47_RS15495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH47_RS15500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CH47_RS15505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH47_RS15515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CH47_RS15520	COG1534	Rna-binding protein
CH47_RS15530	COG2027	D-alanyl-D-alanine carboxypeptidase
CH47_RS15535	COG0745	RESPONSE REGULATOR receiver
CH47_RS15540	COG0642	Histidine kinase
CH47_RS15545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CH47_RS15550	COG0697	spore germination
CH47_RS15555	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CH47_RS15560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CH47_RS15565	COG0142	geranyltranstransferase activity
CH47_RS15575	COG3423	Transcriptional regulator
CH47_RS15580	COG0039	L-malate dehydrogenase activity
CH47_RS15585	COG1438	arginine binding
CH47_RS15595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH47_RS15600	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH47_RS15610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH47_RS15615	COG2105	PFAM AIG2 family protein
CH47_RS15625	COG0729	surface antigen
CH47_RS15630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CH47_RS15635	COG1253	flavin adenine dinucleotide binding
CH47_RS15645	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH47_RS15650	COG1218	3'(2'),5'-bisphosphate nucleotidase
CH47_RS15655	COG0737	Belongs to the 5'-nucleotidase family
CH47_RS15660	COG0545	Peptidyl-prolyl cis-trans isomerase
CH47_RS15665	COG3061	Opacity-associated protein A
CH47_RS15675	COG0359	binds to the 23S rRNA
CH47_RS15680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH47_RS15685	COG2965	DNA replication, synthesis of RNA primer
CH47_RS15690	COG0360	Binds together with S18 to 16S ribosomal RNA
CH47_RS15700	COG1073	alpha beta
CH47_RS15705	COG3650	response to hydrogen peroxide
CH47_RS15710	COG1960	acyl-CoA dehydrogenase activity
CH47_RS15715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH47_RS15720	COG0557	exoribonuclease II activity
CH47_RS15725	COG1959	2 iron, 2 sulfur cluster binding
CH47_RS15730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CH47_RS15735	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH47_RS15740	COG0330	HflC and HflK could
CH47_RS15745	COG0330	HflC and HflK could
CH47_RS15750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH47_RS15755	COG1923	regulation of RNA biosynthetic process
CH47_RS15760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CH47_RS15765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CH47_RS15770	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH47_RS15775	COG0802	atpase or kinase
CH47_RS15780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH47_RS15780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH47_RS15785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH47_RS15805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH47_RS15810	COG1162	GTPase activity
CH47_RS15815	COG0688	phosphatidylethanolamine metabolic process
CH47_RS15820	COG3264	Mechanosensitive ion channel
CH47_RS15820	COG1511	domain protein
CH47_RS15825	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CH47_RS15830	COG1053	succinate dehydrogenase
CH47_RS15835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH47_RS15840	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH47_RS15845	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH47_RS15865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CH47_RS15880	COG0459	protein refolding
CH47_RS15885	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CH47_RS15900	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH47_RS15910	COG4232	protein-disulfide reductase activity
CH47_RS15915	COG1929	Belongs to the glycerate kinase type-1 family
CH47_RS15920	COG1309	transcriptional regulator
CH47_RS15945	COG0667	Aldo Keto reductase
CH47_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
CH47_RS15960	COG1882	Formate acetyltransferase
CH47_RS15965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CH47_RS15970	COG0814	amino acid
CH47_RS15975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH47_RS15985	COG3721	Heme iron utilization protein
CH47_RS16005	COG3720	iron ion transport
CH47_RS16010	COG4558	Periplasmic binding protein
CH47_RS16015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH47_RS16020	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH47_RS16025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH47_RS16035	COG4774	siderophore transport
CH47_RS16040	COG3264	Mechanosensitive ion channel
CH47_RS16040	COG1511	domain protein
CH47_RS16045	COG0612	Peptidase, M16
CH47_RS16050	COG4178	(ABC) transporter
CH47_RS16055	COG4771	TonB-dependent receptor
CH47_RS16060	COG3712	iron ion homeostasis
CH47_RS16075	COG0425	Belongs to the sulfur carrier protein TusA family
CH47_RS16090	COG2197	response regulator
CH47_RS16095	COG1301	dicarboxylic acid transport
CH47_RS16100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CH47_RS16105	COG3162	membrane
CH47_RS16110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH47_RS16145	COG0138	bifunctional purine biosynthesis protein purh
CH47_RS16150	COG0151	Belongs to the GarS family
CH47_RS16170	COG1515	deoxyribonuclease V activity
CH47_RS16175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CH47_RS16180	COG2816	NAD+ diphosphatase activity
CH47_RS16185	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CH47_RS16200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH47_RS16205	COG2104	thiamine diphosphate biosynthetic process
CH47_RS16210	COG2022	thiamine diphosphate biosynthetic process
CH47_RS16220	COG3385	transposase activity
CH47_RS16225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CH47_RS16230	COG0085	RNA polymerase activity
CH47_RS16235	COG0222	ribosome binding
CH47_RS16240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CH47_RS16245	COG0081	regulation of translation
CH47_RS16250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CH47_RS16255	COG0250	Participates in transcription elongation, termination and antitermination
CH47_RS16265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CH47_RS16295	COG1072	(Pantothenic acid kinase))
CH47_RS16300	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CH47_RS16300	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CH47_RS16345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH47_RS16350	COG1739	Uncharacterized protein family UPF0029
CH47_RS16355	COG0006	proline dipeptidase activity
CH47_RS16360	COG1250	3-hydroxyacyl-CoA dehydrogenase
CH47_RS16360	COG1024	Enoyl-CoA hydratase
CH47_RS16365	COG0183	Belongs to the thiolase family
CH47_RS16375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH47_RS16395	COG0805	protein transport
CH47_RS16400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH47_RS16405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH47_RS16410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CH47_RS16420	COG2226	methyltransferase
CH47_RS16425	COG1322	Protein conserved in bacteria
CH47_RS16430	COG0586	Pfam SNARE associated Golgi protein
CH47_RS16435	COG1966	Carbon starvation protein
CH47_RS16450	COG0412	Dienelactone hydrolase
CH47_RS16455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CH47_RS16460	COG0583	DNA-binding transcription factor activity
CH47_RS16465	COG0697	spore germination
CH47_RS16470	COG0679	Auxin Efflux Carrier
CH47_RS16475	COG0584	glycerophosphoryl diester phosphodiesterase
CH47_RS16480	COG3842	ATPase activity
CH47_RS16485	COG0395	ABC-type sugar transport system, permease component
CH47_RS16490	COG1175	transmembrane transport
CH47_RS16495	COG1653	transport
CH47_RS16530	COG0410	ABC transporter
CH47_RS16540	COG4177	L-phenylalanine transmembrane transporter activity
CH47_RS16550	COG0683	leucine binding
CH47_RS16565	COG2177	Part of the ABC transporter FtsEX involved in
CH47_RS16570	COG2884	Cell division ATP-binding protein ftsE
CH47_RS16575	COG0552	protein localization to endoplasmic reticulum
CH47_RS16580	COG0742	ribosomal rna small subunit methyltransferase
CH47_RS16585	COG3776	membrane
CH47_RS16600	COG3714	YhhN family
CH47_RS16605	COG2217	Heavy metal translocating P-type atpase
CH47_RS16610	COG0425	Belongs to the sulfur carrier protein TusA family
CH47_RS16615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH47_RS16625	COG0247	lactate metabolic process
CH47_RS16630	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CH47_RS16635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH47_RS16640	COG2271	Major facilitator Superfamily
CH47_RS16645	COG0584	glycerophosphoryl diester phosphodiesterase
CH47_RS16650	COG0561	phosphatase activity
CH47_RS16655	COG2267	carboxylic ester hydrolase activity
CH47_RS16665	COG1280	lysine exporter protein (LysE YggA)
CH47_RS16670	COG0514	ATP-dependent DNA helicase (RecQ)
CH47_RS16675	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH47_RS16680	COG2050	protein possibly involved in aromatic compounds catabolism
CH47_RS16695	COG5564	TIM-barrel signal transduction protein
CH47_RS16700	COG5441	Belongs to the UPF0261 family
CH47_RS16710	COG0210	DNA helicase
CH47_RS16715	COG1011	Hydrolase
CH47_RS16720	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH47_RS16725	COG3159	Protein conserved in bacteria
CH47_RS16730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CH47_RS16740	COG1965	Belongs to the frataxin family
CH47_RS16745	COG3072	Adenylate cyclase
CH47_RS16750	COG0181	hydroxymethylbilane synthase activity
CH47_RS16755	COG1587	Uroporphyrinogen-III synthase
CH47_RS16760	COG2959	enzyme of heme biosynthesis
CH47_RS16765	COG3071	HemY protein
CH47_RS16805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH47_RS16810	COG2244	polysaccharide biosynthetic process
CH47_RS16815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH47_RS16820	COG0456	acetyltransferase
CH47_RS16825	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH47_RS16830	COG1088	dTDP-glucose 4,6-dehydratase activity
CH47_RS16835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH47_RS16840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH47_RS16845	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH47_RS16850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH47_RS16855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH47_RS16860	COG3118	belongs to the thioredoxin family
CH47_RS16870	COG0248	Ppx GppA phosphatase
CH47_RS16885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH47_RS16895	COG3121	Chaperone
CH47_RS16910	COG3121	Chaperone
CH47_RS16945	COG3385	transposase activity
CH47_RS16950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CH47_RS16955	COG0583	DNA-binding transcription factor activity
CH47_RS16965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH47_RS16970	COG0129	dihydroxy-acid dehydratase activity
CH47_RS16975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH47_RS16980	COG3978	acetolactate synthase activity
CH47_RS16995	COG3085	chromosome segregation
CH47_RS17000	COG0583	DNA-binding transcription factor activity
CH47_RS17005	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS17010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS17015	COG1129	ABC transporter
CH47_RS17020	COG1879	ABC-type sugar transport system periplasmic component
CH47_RS17060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CH47_RS17070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH47_RS17080	COG1309	transcriptional regulator
CH47_RS17085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH47_RS17095	COG0678	peroxiredoxin activity
CH47_RS17095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH47_RS17100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH47_RS17145	COG1629	transport
CH47_RS17150	COG0165	Argininosuccinate lyase
CH47_RS17155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CH47_RS17170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CH47_RS17195	COG0460	homoserine dehydrogenase
CH47_RS17195	COG0527	aspartate kinase activity
CH47_RS17200	COG0626	cystathionine gamma-synthase activity
CH47_RS17205	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
CH47_RS17210	COG0254	rRNA binding
CH47_RS17215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH47_RS17220	COG1609	Transcriptional regulator
CH47_RS17225	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH47_RS17230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CH47_RS17235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CH47_RS17240	COG1575	Belongs to the MenA family. Type 1 subfamily
CH47_RS17245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH47_RS17250	COG3074	FtsZ-dependent cytokinesis
CH47_RS17260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH47_RS17265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH47_RS17270	COG1494	fructose-1,6-bisphosphatase
CH47_RS17275	COG2814	Major facilitator Superfamily
CH47_RS17285	COG3152	Membrane
CH47_RS17295	COG0149	triose-phosphate isomerase activity
CH47_RS17300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH47_RS17305	COG0205	6-phosphofructokinase activity
CH47_RS17310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CH47_RS17315	COG3678	ATP-independent chaperone mediated protein folding
CH47_RS17320	COG0745	RESPONSE REGULATOR receiver
CH47_RS17325	COG2205	protein histidine kinase activity
CH47_RS17330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH47_RS17330	COG2169	Transcriptional regulator
CH47_RS17335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH47_RS17340	COG1045	serine acetyltransferase
CH47_RS17345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CH47_RS17350	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CH47_RS17355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH47_RS17360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH47_RS17365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CH47_RS17370	COG4942	peptidase
CH47_RS17375	COG2861	carbohydrate metabolic process
CH47_RS17380	COG1063	alcohol dehydrogenase
CH47_RS17385	COG0156	8-amino-7-oxononanoate synthase activity
CH47_RS17390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS17395	COG0859	PFAM glycosyl transferase family 9
CH47_RS17400	COG0859	PFAM glycosyl transferase family 9
CH47_RS17405	COG1519	Transferase
CH47_RS17415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CH47_RS17420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CH47_RS17425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CH47_RS17430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CH47_RS17435	COG2003	Belongs to the UPF0758 family
CH47_RS17440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH47_RS17445	COG0756	dUTP diphosphatase activity
CH47_RS17450	COG1309	transcriptional regulator
CH47_RS17455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CH47_RS17460	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CH47_RS17465	COG1561	YicC-like family, N-terminal region
CH47_RS17535	COG5001	Diguanylate cyclase
CH47_RS17540	COG1024	Enoyl-CoA hydratase
CH47_RS17545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH47_RS17555	COG2860	membrane
CH47_RS17560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CH47_RS17570	COG1758	RNA polymerase activity
CH47_RS17575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH47_RS17580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH47_RS17585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH47_RS17590	COG0786	glutamate:sodium symporter activity
CH47_RS17595	COG2233	PERMEase
CH47_RS17600	COG2982	Protein involved in outer membrane biogenesis
CH47_RS17630	COG3423	Transcriptional regulator
CH47_RS17635	COG0456	acetyltransferase
CH47_RS17640	COG1490	D-aminoacyl-tRNA deacylase activity
CH47_RS17645	COG1295	ribonuclease BN
CH47_RS17650	COG1011	Hydrolase
CH47_RS17665	COG3852	Histidine kinase
CH47_RS17675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH47_RS17680	COG3078	GTPase activator activity
CH47_RS17685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CH47_RS17690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH47_RS17690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH47_RS17695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH47_RS17700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH47_RS17705	COG3084	Protein conserved in bacteria
CH47_RS17715	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH47_RS17740	COG2186	Transcriptional regulator
CH47_RS17745	COG0477	Major facilitator Superfamily
CH47_RS17750	COG1609	Transcriptional regulator
CH47_RS17755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH47_RS17760	COG1879	ABC-type sugar transport system periplasmic component
CH47_RS17765	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH47_RS17775	COG1869	D-ribose catabolic process
CH47_RS17780	COG3158	transport of potassium into the cell
CH47_RS17785	COG0714	Associated with various cellular activities
CH47_RS17800	COG2502	aspartate--ammonia ligase
CH47_RS17805	COG1522	sequence-specific DNA binding
CH47_RS17810	COG0716	FMN binding
CH47_RS17815	COG0445	tRNA wobble uridine modification
CH47_RS17820	COG0357	Ribosomal RNA small subunit methyltransferase G
CH47_RS17825	COG3312	ion transport
CH47_RS17830	COG0356	it plays a direct role in the translocation of protons across the membrane
CH47_RS17840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CH47_RS17845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CH47_RS17850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CH47_RS17855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CH47_RS17860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CH47_RS17865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CH47_RS17870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CH47_RS17885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH47_RS17890	COG0573	inorganic phosphate transmembrane transporter activity
CH47_RS17895	COG0581	inorganic phosphate transmembrane transporter activity
CH47_RS17905	COG0704	Plays a role in the regulation of phosphate uptake
CH47_RS17915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS17920	COG0765	amino acid transport
CH47_RS17925	COG0765	amino acid transport
CH47_RS17930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH47_RS17935	COG2252	PERMEase
CH47_RS17945	COG4566	intracellular signal transduction
CH47_RS17950	COG4191	Histidine kinase
CH47_RS17955	COG0431	NADPH-dependent FMN reductase
CH47_RS17960	COG0840	transmembrane signaling receptor activity
CH47_RS17965	COG2011	ABC-type metal ion transport system permease component
CH47_RS17980	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CH47_RS17985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CH47_RS17990	COG0706	membrane insertase activity
CH47_RS17995	COG0594	ribonuclease P activity
CH47_RS18000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH47_RS18005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CH47_RS18010	COG0592	DNA-directed DNA polymerase activity
CH47_RS18015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CH47_RS18020	COG0187	DNA topoisomerase II activity
CH47_RS18025	COG0561	phosphatase activity
CH47_RS18030	COG2423	ornithine cyclodeaminase activity
CH47_RS18035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH47_RS18050	COG3727	T/G mismatch-specific endonuclease activity
CH47_RS18060	COG0823	Involved in the tonB-independent uptake of proteins
CH47_RS18065	COG5645	(Lipo)protein
CH47_RS18080	COG0569	domain protein
CH47_RS18080	COG2985	domain, Protein
CH47_RS18085	COG3977	Valine--pyruvate aminotransferase
CH47_RS18090	COG0366	Alpha amylase catalytic
CH47_RS18095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH47_RS18110	COG2885	chlorophyll binding
CH47_RS18125	COG0456	acetyltransferase
CH47_RS18130	COG2818	Glycosylase
CH47_RS18135	COG0752	glycyl-tRNA synthetase alpha subunit
CH47_RS18140	COG0751	glycine-tRNA ligase activity
CH47_RS18155	COG2213	PTS system mannitol-specific
CH47_RS18155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS18160	COG0246	Mannitol dehydrogenase
CH47_RS18165	COG3722	fumarate hydratase activity
CH47_RS18175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH47_RS18195	COG2258	MOSC domain
CH47_RS18200	COG0840	transmembrane signaling receptor activity
CH47_RS18205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH47_RS18210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CH47_RS18215	COG3383	formate dehydrogenase (NAD+) activity
CH47_RS18215	COG0243	molybdopterin cofactor binding
CH47_RS18220	COG0243	molybdopterin cofactor binding
CH47_RS18220	COG3383	formate dehydrogenase (NAD+) activity
CH47_RS18225	COG0437	4 iron, 4 sulfur cluster binding
CH47_RS18230	COG2864	formate dehydrogenase
CH47_RS18235	COG3058	Necessary for formate dehydrogenase activity
CH47_RS18240	COG1921	L-seryl-tRNASec selenium transferase activity
CH47_RS18245	COG3276	selenocysteine insertion sequence binding
CH47_RS18255	COG3550	peptidyl-serine autophosphorylation
CH47_RS18265	COG3274	enterobacterial common antigen metabolic process
CH47_RS18280	COG3121	Chaperone
CH47_RS18285	COG1070	Carbohydrate kinase
CH47_RS18290	COG2115	Belongs to the xylose isomerase family
CH47_RS18295	COG4213	ABC transporter substrate-binding protein
CH47_RS18305	COG4214	carbohydrate transport
CH47_RS18310	COG1609	Transcriptional regulator
CH47_RS18310	COG2207	Transcriptional regulator
CH47_RS18320	COG0582	viral genome integration into host DNA
CH47_RS18345	COG3177	Filamentation induced by cAMP protein fic
CH47_RS18375	COG1609	Transcriptional regulator
CH47_RS18380	COG1940	carbohydrate kinase activity
CH47_RS18385	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH47_RS18390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH47_RS18395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH47_RS18400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH47_RS18415	COG2723	6-phospho-beta-galactosidase activity
CH47_RS18420	COG1482	cell wall glycoprotein biosynthetic process
CH47_RS18425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CH47_RS18430	COG2986	histidine ammonia-lyase
CH47_RS18445	COG1764	response to oxidative stress
CH47_RS18450	COG2194	sulfuric ester hydrolase activity
CH47_RS18455	COG2197	response regulator
CH47_RS18460	COG3851	Histidine kinase
CH47_RS18465	COG2271	Major facilitator Superfamily
CH47_RS18475	COG3210	domain, Protein
CH47_RS18480	COG2831	hemolysin activation secretion protein
CH47_RS18485	COG3210	domain, Protein
CH47_RS18490	COG0747	negative chemotaxis
CH47_RS18495	COG0601	transmembrane transport
CH47_RS18500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH47_RS18505	COG0444	Belongs to the ABC transporter superfamily
CH47_RS18510	COG4608	Belongs to the ABC transporter superfamily
CH47_RS18515	COG2194	sulfuric ester hydrolase activity
CH47_RS18535	COG1192	Involved in chromosome partitioning
CH47_RS18540	COG1215	transferase activity, transferring glycosyl groups
CH47_RS18545	COG1215	transferase activity, transferring glycosyl groups
CH47_RS18550	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH47_RS18555	COG0457	Tetratricopeptide repeat
CH47_RS18555	COG3118	belongs to the thioredoxin family
CH47_RS18560	COG2199	diguanylate cyclase activity
CH47_RS18560	COG2200	EAL domain
CH47_RS18565	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH47_RS18580	COG1301	dicarboxylic acid transport
CH47_RS18585	COG0612	Peptidase, M16
CH47_RS18590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH47_RS18595	COG1942	4-Oxalocrotonate Tautomerase
CH47_RS18600	COG2200	EAL domain
CH47_RS18605	COG2982	Protein involved in outer membrane biogenesis
CH47_RS18610	COG2134	cdp-diacylglycerol pyrophosphatase
CH47_RS18615	COG1295	ribonuclease BN
CH47_RS18625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH47_RS18630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH47_RS18640	COG0742	ribosomal rna small subunit methyltransferase
CH47_RS18645	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH47_RS18655	COG0589	response to stress
CH47_RS18665	COG0306	phosphate transporter
CH47_RS18670	COG2081	HI0933 family
CH47_RS18675	COG1301	dicarboxylic acid transport
CH47_RS18690	COG3799	methylaspartate ammonia-lyase activity
CH47_RS18695	COG4865	methylaspartate mutase activity
CH47_RS18705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CH47_RS18715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CH47_RS18715	COG1648	precorrin-2 dehydrogenase activity
CH47_RS18720	COG0583	DNA-binding transcription factor activity
CH47_RS18725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH47_RS18725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH47_RS18735	COG0561	phosphatase activity
CH47_RS18740	COG0583	DNA-binding transcription factor activity
CH47_RS18745	COG2814	Major facilitator Superfamily
CH47_RS18755	COG3718	enzyme involved in inositol metabolism
CH47_RS18765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH47_RS18775	COG0673	inositol 2-dehydrogenase activity
CH47_RS18780	COG1082	Xylose isomerase domain protein TIM barrel
CH47_RS18785	COG1247	-acetyltransferase
CH47_RS18790	COG1741	Belongs to the pirin family
CH47_RS18795	COG1609	Transcriptional regulator
CH47_RS18800	COG2610	gluconate transmembrane transporter activity
CH47_RS18805	COG3265	gluconokinase activity
CH47_RS18810	COG2095	MarC family integral membrane protein
CH47_RS18815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH47_RS18835	COG3275	phosphorelay sensor kinase activity
CH47_RS18840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CH47_RS18845	COG1523	belongs to the glycosyl hydrolase 13 family
CH47_RS18855	COG0297	glycogen (starch) synthase activity
CH47_RS18860	COG0058	SHG alpha-glucan phosphorylase activity
CH47_RS18865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH47_RS18880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH47_RS18895	COG2183	response to ionizing radiation
CH47_RS18900	COG1918	ferrous iron import across plasma membrane
CH47_RS18905	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CH47_RS18920	COG0596	Alpha beta hydrolase
CH47_RS18930	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CH47_RS18930	COG0316	Belongs to the HesB IscA family
CH47_RS18935	COG1640	4-alpha-glucanotransferase
CH47_RS18940	COG0058	SHG alpha-glucan phosphorylase activity
CH47_RS18945	COG2909	trisaccharide binding
CH47_RS18955	COG0705	Rhomboid family
CH47_RS18960	COG1349	DNA-binding transcription factor activity
CH47_RS18965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CH47_RS18975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH47_RS18980	COG1011	Hydrolase
CH47_RS18990	COG0494	nUDIX hydrolase
CH47_RS18995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH47_RS19020	COG4796	Type ii and iii secretion system protein
CH47_RS19025	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CH47_RS19045	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH47_RS19055	COG0180	Tryptophanyl-tRNA synthetase
CH47_RS19060	COG1648	precorrin-2 dehydrogenase activity
CH47_RS19060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CH47_RS19075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH47_RS19080	COG0402	S-adenosylhomocysteine deaminase activity
CH47_RS19085	COG0738	Major facilitator superfamily
CH47_RS19095	COG1486	melibiose metabolic process
CH47_RS19100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH47_RS19105	COG0433	COG0433 Predicted ATPase
CH47_RS19120	COG1289	transmembrane transporter activity
CH47_RS19130	COG1765	OsmC-like protein
CH47_RS19135	COG3954	Phosphoribulokinase
CH47_RS19140	COG3089	Belongs to the UPF0270 family
CH47_RS19145	COG0429	hydrolase of the alpha beta-hydrolase fold
CH47_RS19160	COG4521	taurine ABC transporter
CH47_RS19170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH47_RS19175	COG2175	clavaminate synthase activity
CH47_RS19185	COG1216	Glycosyl transferase, family 2
CH47_RS19190	COG0488	(ABC) transporter
CH47_RS19195	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH47_RS19205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH47_RS19210	COG1047	Peptidyl-prolyl cis-trans
CH47_RS19215	COG2900	Belongs to the SlyX family
CH47_RS19220	COG0545	Peptidyl-prolyl cis-trans isomerase
CH47_RS19225	COG2964	Protein conserved in bacteria
CH47_RS19230	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH47_RS19235	COG2923	Belongs to the DsrF TusC family
CH47_RS19240	COG2168	tRNA wobble position uridine thiolation
CH47_RS19245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH47_RS19250	COG0049	tRNA binding
CH47_RS19260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CH47_RS19275	COG0051	transcription antitermination factor activity, RNA binding
CH47_RS19280	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CH47_RS19285	COG0088	Forms part of the polypeptide exit tunnel
CH47_RS19290	COG0089	rRNA binding
CH47_RS19295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CH47_RS19300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH47_RS19305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CH47_RS19310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH47_RS19315	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH47_RS19320	COG0255	Belongs to the universal ribosomal protein uL29 family
CH47_RS19325	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH47_RS19330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH47_RS19335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CH47_RS19340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CH47_RS19345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CH47_RS19350	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CH47_RS19355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CH47_RS19360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CH47_RS19365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CH47_RS19370	COG1841	ribosomal large subunit assembly
CH47_RS19375	COG0200	Binds to the 23S rRNA
CH47_RS19380	COG0201	protein transport
CH47_RS19385	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH47_RS19390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CH47_RS19395	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CH47_RS19400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH47_RS19405	COG0202	RNA polymerase activity
CH47_RS19410	COG0203	ribosomal protein L17
CH47_RS19420	COG0789	Transcriptional regulator
CH47_RS19425	COG3036	rescue of stalled ribosome
CH47_RS19430	COG1970	mechanosensitive ion channel activity
CH47_RS19440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CH47_RS19440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CH47_RS19445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CH47_RS19450	COG0242	peptide deformylase activity
CH47_RS19455	COG0758	DNA mediated transformation
CH47_RS19465	COG0551	DNA topoisomerase type I activity
CH47_RS19470	COG0009	L-threonylcarbamoyladenylate synthase
CH47_RS19475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH47_RS19480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH47_RS19520	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CH47_RS19525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH47_RS19535	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CH47_RS19540	COG1414	Transcriptional regulator
CH47_RS19545	COG0646	methionine synthase
CH47_RS19545	COG1410	methionine synthase
CH47_RS19555	COG0527	aspartate kinase activity
CH47_RS19565	COG0166	Belongs to the GPI family
CH47_RS19570	COG3223	Belongs to the PsiE family
CH47_RS19575	COG3833	ABC-type maltose transport systems, permease component
CH47_RS19580	COG1175	transmembrane transport
CH47_RS19585	COG2182	Extracellular solute-binding protein
CH47_RS19595	COG4580	involved in the transport of maltose and maltodextrins
CH47_RS19610	COG3161	chorismate lyase activity
CH47_RS19615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CH47_RS19620	COG2937	Belongs to the GPAT DAPAT family
CH47_RS19625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH47_RS19630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CH47_RS19635	COG3237	CsbD-like
CH47_RS19640	COG0735	belongs to the Fur family
CH47_RS19670	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CH47_RS19675	COG5532	Uncharacterized conserved protein (DUF2303)
CH47_RS19710	COG1802	Transcriptional regulator
CH47_RS19710	COG4626	Terminase
CH47_RS19730	COG1403	HNH endonuclease
CH47_RS19740	COG1280	lysine exporter protein (LysE YggA)
CH47_RS19770	COG3772	lysozyme
CH47_RS19780	COG3646	Phage regulatory protein
CH47_RS19875	COG4386	tail sheath protein
CH47_RS19935	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CH47_RS19950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH47_RS19980	COG1448	Aminotransferase
CH47_RS19985	COG2315	Protein conserved in bacteria
CH47_RS19990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH47_RS20000	COG3550	peptidyl-serine autophosphorylation
CH47_RS20005	COG3620	sequence-specific DNA binding
CH47_RS20015	COG2252	PERMEase
CH47_RS20020	COG0025	NhaP-type Na H and K H
CH47_RS20025	COG0583	DNA-binding transcription factor activity
CH47_RS20030	COG1380	Effector of murein hydrolase LrgA
CH47_RS20040	COG1126	abc transporter atp-binding protein
CH47_RS20045	COG0765	amino acid transport
CH47_RS20050	COG4597	amino acid ABC transporter
CH47_RS20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH47_RS20065	COG1560	Kdo2-lipid A biosynthetic process
CH47_RS20080	COG1278	Cold shock
CH47_RS20085	COG1278	Cold shock
CH47_RS20090	COG3133	Outer membrane lipoprotein
CH47_RS20100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH47_RS20105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH47_RS20110	COG2264	protein methyltransferase activity
CH47_RS20115	COG4145	pantothenate transmembrane transporter activity
CH47_RS20120	COG3924	membrane
CH47_RS20125	COG0439	Biotin carboxylase
CH47_RS20130	COG0511	ligase activity, forming carbon-carbon bonds
CH47_RS20135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CH47_RS20140	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CH47_RS20150	COG0604	alcohol dehydrogenase
CH47_RS20160	COG1077	Cell shape determining protein MreB Mrl
CH47_RS20165	COG1792	Involved in formation and maintenance of cell shape
CH47_RS20170	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH47_RS20175	COG0424	maF-like protein
CH47_RS20180	COG1530	ribonuclease E activity
CH47_RS20185	COG3164	Protein of unknown function
CH47_RS20190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH47_RS20195	COG0312	modulator of DNA gyrase
CH47_RS20200	COG0583	DNA-binding transcription factor activity
CH47_RS20210	COG1566	PFAM secretion protein HlyD family protein
CH47_RS20215	COG1289	transmembrane transporter activity
CH47_RS20230	COG2732	(Barnase) inhibitor
CH47_RS20235	COG3028	Belongs to the UPF0307 family
CH47_RS20240	COG0312	modulator of DNA gyrase
CH47_RS20245	COG3783	Cytochrome b(562)
CH47_RS20250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH47_RS20280	COG3964	amidohydrolase
CH47_RS20295	COG2706	6-phosphogluconolactonase activity
CH47_RS20300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS20300	COG3711	transcriptional antiterminator
CH47_RS20305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CH47_RS20315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS20315	COG1263	PTS System
CH47_RS20320	COG0366	Alpha amylase catalytic
CH47_RS20350	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CH47_RS20355	COG0540	Belongs to the ATCase OTCase family
CH47_RS20380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH47_RS20385	COG1660	Displays ATPase and GTPase activities
CH47_RS20400	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH47_RS20405	COG1137	ATPase activity
CH47_RS20410	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH47_RS20415	COG3117	lipopolysaccharide transmembrane transporter activity
CH47_RS20420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH47_RS20425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH47_RS20425	COG0517	IMP dehydrogenase activity
CH47_RS20430	COG0530	calcium, potassium:sodium antiporter activity
CH47_RS20435	COG1127	ABC transporter
CH47_RS20440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH47_RS20445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH47_RS20450	COG2854	intermembrane phospholipid transfer
CH47_RS20455	COG3113	response to antibiotic
CH47_RS20460	COG5007	Belongs to the BolA IbaG family
CH47_RS20465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CH47_RS20470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH47_RS20475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH47_RS20480	COG3105	Protein conserved in bacteria
CH47_RS20485	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH47_RS20490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CH47_RS20495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CH47_RS20500	COG0625	glutathione transferase activity
CH47_RS20505	COG2969	positive regulation of protein catabolic process
CH47_RS20515	COG0493	'glutamate synthase
CH47_RS20520	COG0070	glutamate synthase
CH47_RS20520	COG0069	glutamate synthase activity
CH47_RS20520	COG0067	glutamate synthase
CH47_RS20525	COG1242	4 iron, 4 sulfur cluster binding
CH47_RS20530	COG5002	protein histidine kinase activity
CH47_RS20530	COG2198	Histidine kinase
CH47_RS20530	COG0784	Response regulator, receiver
CH47_RS20535	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH47_RS20540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH47_RS20545	COG2823	Periplasmic or secreted lipoprotein
CH47_RS20550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CH47_RS20555	COG0792	nuclease activity
CH47_RS20565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH47_RS20580	COG0667	Aldo Keto reductase
CH47_RS20585	COG1064	alcohol dehydrogenase
CH47_RS20590	COG1741	Belongs to the pirin family
CH47_RS20595	COG0583	DNA-binding transcription factor activity
CH47_RS20600	COG0435	Glutathione S-transferase
CH47_RS20605	COG2259	Doxx family
CH47_RS20615	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH47_RS20620	COG4575	ribosome binding
CH47_RS20635	COG0586	Pfam SNARE associated Golgi protein
CH47_RS20650	COG2271	Major facilitator Superfamily
CH47_RS20655	COG1904	glucuronate isomerase
CH47_RS20660	COG0246	Mannitol dehydrogenase
CH47_RS20665	COG2721	sulfolactate sulfo-lyase activity
CH47_RS20675	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CH47_RS20680	COG0861	Integral membrane protein TerC family
CH47_RS20685	COG0673	inositol 2-dehydrogenase activity
CH47_RS20690	COG1451	nucleotide metabolic process
CH47_RS20700	COG2813	Specifically methylates the guanine in position
CH47_RS20710	COG1902	pentaerythritol trinitrate reductase activity
CH47_RS20710	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH47_RS20720	COG3247	response to pH
CH47_RS20725	COG2814	Major facilitator Superfamily
CH47_RS20735	COG0076	glutamate decarboxylase activity
CH47_RS20740	COG0531	amino acid
CH47_RS20750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH47_RS20750	COG1263	PTS System
CH47_RS20755	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CH47_RS20765	COG1472	Belongs to the glycosyl hydrolase 3 family
CH47_RS20775	COG3876	Protein conserved in bacteria
CH47_RS20790	COG0358	DNA primase activity
CH47_RS20795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH47_RS20800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CH47_RS20805	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CH47_RS20810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH47_RS20815	COG1968	undecaprenyl-diphosphatase activity
CH47_RS20820	COG0617	tRNA 3'-terminal CCA addition
CH47_RS20825	COG4991	sh3 domain protein
CH47_RS20830	COG3025	triphosphatase activity
CH47_RS20835	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CH47_RS20840	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CH47_RS20840	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CH47_RS20845	COG0531	amino acid
CH47_RS20855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CH47_RS20860	COG3384	dioxygenase
CH47_RS20865	COG0754	glutathionylspermidine amidase activity
CH47_RS20870	COG5463	Belongs to the UPF0441 family
CH47_RS20880	COG1538	Outer membrane efflux protein
CH47_RS20885	COG0494	nUDIX hydrolase
CH47_RS20890	COG3151	Protein conserved in bacteria
CH47_RS20900	COG3150	esterase
CH47_RS20915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH47_RS20920	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH47_RS20925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH47_RS20935	COG2132	Multicopper oxidase
CH47_RS20945	COG0656	L-ascorbic acid biosynthetic process
CH47_RS20950	COG1979	alcohol dehydrogenase
CH47_RS20955	COG2207	Transcriptional regulator
CH47_RS20960	COG0586	Pfam SNARE associated Golgi protein
CH47_RS20975	COG0848	biopolymer transport protein
CH47_RS21025	COG4964	Belongs to the GSP D family
CH47_RS21055	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH47_RS21060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH47_RS21090	COG1120	ATPase activity
CH47_RS21095	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH47_RS21100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH47_RS21110	COG4592	Periplasmic binding protein
CH47_RS21115	COG2271	Major facilitator Superfamily
CH47_RS21120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH47_RS21125	COG0840	transmembrane signaling receptor activity
CH47_RS21150	COG3133	Outer membrane lipoprotein
CH47_RS21165	COG0437	4 iron, 4 sulfur cluster binding
CH47_RS21190	COG3328	transposase activity
CH47_RS21195	COG2211	Major facilitator Superfamily
CH47_RS21205	COG2197	response regulator