locus-tag	class	description
YE105_RS00005	COG0716	FMN binding
YE105_RS00010	COG1522	sequence-specific DNA binding
YE105_RS00015	COG2502	aspartate--ammonia ligase
YE105_RS00025	COG2425	protein containing a von Willebrand factor type A (vWA) domain
YE105_RS00030	COG0714	Associated with various cellular activities
YE105_RS00035	COG3158	transport of potassium into the cell
YE105_RS00040	COG1869	D-ribose catabolic process
YE105_RS00050	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS00055	COG1879	ABC-type sugar transport system periplasmic component
YE105_RS00060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_RS00065	COG1609	Transcriptional regulator
YE105_RS00070	COG0477	Major facilitator Superfamily
YE105_RS00075	COG2186	Transcriptional regulator
YE105_RS00110	COG1763	Mo-molybdopterin cofactor biosynthetic process
YE105_RS00120	COG3084	Protein conserved in bacteria
YE105_RS00125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YE105_RS00130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YE105_RS00135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS00135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS00140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YE105_RS00145	COG3078	GTPase activator activity
YE105_RS00150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YE105_RS00160	COG3852	Histidine kinase
YE105_RS00180	COG1011	Hydrolase
YE105_RS00185	COG1295	ribonuclease BN
YE105_RS00190	COG1490	D-aminoacyl-tRNA deacylase activity
YE105_RS00195	COG0456	acetyltransferase
YE105_RS00200	COG3423	Transcriptional regulator
YE105_RS00220	COG2982	Protein involved in outer membrane biogenesis
YE105_RS00225	COG2233	PERMEase
YE105_RS00230	COG0786	glutamate:sodium symporter activity
YE105_RS00240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YE105_RS00245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YE105_RS00250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YE105_RS00255	COG1758	RNA polymerase activity
YE105_RS00265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YE105_RS00270	COG2860	membrane
YE105_RS00280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YE105_RS00285	COG1024	Enoyl-CoA hydratase
YE105_RS00290	COG5001	Diguanylate cyclase
YE105_RS00305	COG1561	YicC-like family, N-terminal region
YE105_RS00310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YE105_RS00315	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YE105_RS00320	COG1309	transcriptional regulator
YE105_RS00325	COG0756	dUTP diphosphatase activity
YE105_RS00330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YE105_RS00335	COG2003	Belongs to the UPF0758 family
YE105_RS00340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YE105_RS00345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YE105_RS00350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YE105_RS00355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YE105_RS00365	COG1519	Transferase
YE105_RS00370	COG0859	PFAM glycosyl transferase family 9
YE105_RS00375	COG0859	PFAM glycosyl transferase family 9
YE105_RS00380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_RS00385	COG0156	8-amino-7-oxononanoate synthase activity
YE105_RS00390	COG1063	alcohol dehydrogenase
YE105_RS00410	COG2861	carbohydrate metabolic process
YE105_RS00415	COG4942	peptidase
YE105_RS00420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YE105_RS00425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YE105_RS00430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YE105_RS00435	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YE105_RS00440	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YE105_RS00445	COG1045	serine acetyltransferase
YE105_RS00450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YE105_RS00455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YE105_RS00455	COG2169	Transcriptional regulator
YE105_RS00460	COG2205	protein histidine kinase activity
YE105_RS00465	COG0745	RESPONSE REGULATOR receiver
YE105_RS00470	COG3678	ATP-independent chaperone mediated protein folding
YE105_RS00475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
YE105_RS00485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YE105_RS00495	COG0149	triose-phosphate isomerase activity
YE105_RS00505	COG3152	Membrane
YE105_RS00525	COG2814	Major facilitator Superfamily
YE105_RS00530	COG1494	fructose-1,6-bisphosphatase
YE105_RS00540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YE105_RS00545	COG3074	FtsZ-dependent cytokinesis
YE105_RS00550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YE105_RS00555	COG1575	Belongs to the MenA family. Type 1 subfamily
YE105_RS00560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YE105_RS00565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YE105_RS00570	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YE105_RS00575	COG1609	Transcriptional regulator
YE105_RS00580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YE105_RS00585	COG0254	rRNA binding
YE105_RS00590	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YE105_RS00595	COG0626	cystathionine gamma-synthase activity
YE105_RS00600	COG0527	aspartate kinase activity
YE105_RS00600	COG0460	homoserine dehydrogenase
YE105_RS00610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YE105_RS00625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YE105_RS00630	COG0165	Argininosuccinate lyase
YE105_RS00635	COG1629	transport
YE105_RS00670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_RS00675	COG0678	peroxiredoxin activity
YE105_RS00675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YE105_RS00685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_RS00690	COG1309	transcriptional regulator
YE105_RS00700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YE105_RS00710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YE105_RS00750	COG1879	ABC-type sugar transport system periplasmic component
YE105_RS00755	COG1129	ABC transporter
YE105_RS00760	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS00765	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS00770	COG0583	DNA-binding transcription factor activity
YE105_RS00775	COG3085	chromosome segregation
YE105_RS00790	COG3978	acetolactate synthase activity
YE105_RS00795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YE105_RS00800	COG0129	dihydroxy-acid dehydratase activity
YE105_RS00820	COG0583	DNA-binding transcription factor activity
YE105_RS00825	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YE105_RS00850	COG3121	Chaperone
YE105_RS00865	COG3121	Chaperone
YE105_RS00875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YE105_RS00890	COG0248	Ppx GppA phosphatase
YE105_RS00900	COG3118	belongs to the thioredoxin family
YE105_RS00905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YE105_RS00910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YE105_RS00915	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YE105_RS00920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YE105_RS00925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YE105_RS00930	COG1088	dTDP-glucose 4,6-dehydratase activity
YE105_RS00935	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YE105_RS00940	COG0456	acetyltransferase
YE105_RS00945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YE105_RS00950	COG2244	polysaccharide biosynthetic process
YE105_RS00955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YE105_RS01000	COG3071	HemY protein
YE105_RS01005	COG2959	enzyme of heme biosynthesis
YE105_RS01010	COG1587	Uroporphyrinogen-III synthase
YE105_RS01015	COG0181	hydroxymethylbilane synthase activity
YE105_RS01020	COG3072	Adenylate cyclase
YE105_RS01025	COG1965	Belongs to the frataxin family
YE105_RS01035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YE105_RS01040	COG3159	Protein conserved in bacteria
YE105_RS01045	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YE105_RS01050	COG1011	Hydrolase
YE105_RS01055	COG0210	DNA helicase
YE105_RS01065	COG5441	Belongs to the UPF0261 family
YE105_RS01070	COG5564	TIM-barrel signal transduction protein
YE105_RS01085	COG2050	protein possibly involved in aromatic compounds catabolism
YE105_RS01090	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YE105_RS01095	COG0514	ATP-dependent DNA helicase (RecQ)
YE105_RS01100	COG1280	lysine exporter protein (LysE YggA)
YE105_RS01105	COG1280	lysine exporter protein (LysE YggA)
YE105_RS01110	COG2267	carboxylic ester hydrolase activity
YE105_RS01115	COG0561	phosphatase activity
YE105_RS01120	COG0584	glycerophosphoryl diester phosphodiesterase
YE105_RS01125	COG2271	Major facilitator Superfamily
YE105_RS01130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YE105_RS01135	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
YE105_RS01140	COG0247	lactate metabolic process
YE105_RS01150	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YE105_RS01155	COG0425	Belongs to the sulfur carrier protein TusA family
YE105_RS01160	COG2217	Heavy metal translocating P-type atpase
YE105_RS01165	COG3714	YhhN family
YE105_RS01180	COG3776	membrane
YE105_RS01185	COG0742	ribosomal rna small subunit methyltransferase
YE105_RS01190	COG0552	protein localization to endoplasmic reticulum
YE105_RS01195	COG2884	Cell division ATP-binding protein ftsE
YE105_RS01200	COG2177	Part of the ABC transporter FtsEX involved in
YE105_RS01225	COG0683	leucine binding
YE105_RS01235	COG4177	L-phenylalanine transmembrane transporter activity
YE105_RS01245	COG0410	ABC transporter
YE105_RS01280	COG1653	transport
YE105_RS01285	COG1175	transmembrane transport
YE105_RS01290	COG0395	ABC-type sugar transport system, permease component
YE105_RS01295	COG3842	ATPase activity
YE105_RS01300	COG0584	glycerophosphoryl diester phosphodiesterase
YE105_RS01305	COG0679	Auxin Efflux Carrier
YE105_RS01310	COG0697	spore germination
YE105_RS01315	COG0583	DNA-binding transcription factor activity
YE105_RS01320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YE105_RS01325	COG0412	Dienelactone hydrolase
YE105_RS01350	COG1966	Carbon starvation protein
YE105_RS01355	COG0586	Pfam SNARE associated Golgi protein
YE105_RS01360	COG1322	Protein conserved in bacteria
YE105_RS01365	COG2226	methyltransferase
YE105_RS01375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YE105_RS01380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YE105_RS01385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YE105_RS01390	COG0805	protein transport
YE105_RS01410	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YE105_RS01420	COG0183	Belongs to the thiolase family
YE105_RS01425	COG1250	3-hydroxyacyl-CoA dehydrogenase
YE105_RS01425	COG1024	Enoyl-CoA hydratase
YE105_RS01430	COG0006	proline dipeptidase activity
YE105_RS01435	COG1739	Uncharacterized protein family UPF0029
YE105_RS01440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YE105_RS01485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YE105_RS01485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YE105_RS01490	COG1072	(Pantothenic acid kinase))
YE105_RS01520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YE105_RS01530	COG0250	Participates in transcription elongation, termination and antitermination
YE105_RS01535	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YE105_RS01540	COG0081	regulation of translation
YE105_RS01545	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YE105_RS01555	COG0085	RNA polymerase activity
YE105_RS01560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YE105_RS01580	COG2022	thiamine diphosphate biosynthetic process
YE105_RS01585	COG2104	thiamine diphosphate biosynthetic process
YE105_RS01590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YE105_RS01605	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
YE105_RS01610	COG2816	NAD+ diphosphatase activity
YE105_RS01615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YE105_RS01620	COG1515	deoxyribonuclease V activity
YE105_RS01640	COG0151	Belongs to the GarS family
YE105_RS01645	COG0138	bifunctional purine biosynthesis protein purh
YE105_RS01685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YE105_RS01690	COG3162	membrane
YE105_RS01695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YE105_RS01700	COG1301	dicarboxylic acid transport
YE105_RS01705	COG2197	response regulator
YE105_RS01710	COG0784	Response regulator, receiver
YE105_RS01710	COG2205	protein histidine kinase activity
YE105_RS01710	COG5002	protein histidine kinase activity
YE105_RS01865	COG2391	methyltransferase activity
YE105_RS01870	COG0425	Belongs to the sulfur carrier protein TusA family
YE105_RS01885	COG3712	iron ion homeostasis
YE105_RS01890	COG4771	TonB-dependent receptor
YE105_RS01895	COG4178	(ABC) transporter
YE105_RS01900	COG0612	Peptidase, M16
YE105_RS01905	COG2161	toxin-antitoxin pair type II binding
YE105_RS01910	COG4115	mRNA cleavage
YE105_RS01915	COG1511	domain protein
YE105_RS01915	COG3264	Mechanosensitive ion channel
YE105_RS01920	COG4774	siderophore transport
YE105_RS01930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_RS01935	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YE105_RS01940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_RS01945	COG4558	Periplasmic binding protein
YE105_RS01950	COG3720	iron ion transport
YE105_RS01970	COG3721	Heme iron utilization protein
YE105_RS01980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YE105_RS01985	COG0814	amino acid
YE105_RS01990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YE105_RS01995	COG1882	Formate acetyltransferase
YE105_RS02005	COG1309	transcriptional regulator
YE105_RS02010	COG1929	Belongs to the glycerate kinase type-1 family
YE105_RS02015	COG4232	protein-disulfide reductase activity
YE105_RS02025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YE105_RS02040	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YE105_RS02045	COG0459	protein refolding
YE105_RS02065	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YE105_RS02085	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YE105_RS02090	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YE105_RS02095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YE105_RS02100	COG1053	succinate dehydrogenase
YE105_RS02105	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
YE105_RS02110	COG1511	domain protein
YE105_RS02110	COG3264	Mechanosensitive ion channel
YE105_RS02115	COG0688	phosphatidylethanolamine metabolic process
YE105_RS02120	COG1162	GTPase activity
YE105_RS02125	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YE105_RS02135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YE105_RS02140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YE105_RS02140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YE105_RS02145	COG0802	atpase or kinase
YE105_RS02150	COG0860	N-Acetylmuramoyl-L-alanine amidase
YE105_RS02155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YE105_RS02160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YE105_RS02165	COG1923	regulation of RNA biosynthetic process
YE105_RS02170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YE105_RS02175	COG0330	HflC and HflK could
YE105_RS02180	COG0330	HflC and HflK could
YE105_RS02185	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YE105_RS02190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YE105_RS02195	COG1959	2 iron, 2 sulfur cluster binding
YE105_RS02200	COG0557	exoribonuclease II activity
YE105_RS02205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YE105_RS02210	COG1960	acyl-CoA dehydrogenase activity
YE105_RS02215	COG3650	response to hydrogen peroxide
YE105_RS02220	COG1073	alpha beta
YE105_RS02230	COG0360	Binds together with S18 to 16S ribosomal RNA
YE105_RS02235	COG2965	DNA replication, synthesis of RNA primer
YE105_RS02240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YE105_RS02245	COG0359	binds to the 23S rRNA
YE105_RS02255	COG3061	Opacity-associated protein A
YE105_RS02260	COG0545	Peptidyl-prolyl cis-trans isomerase
YE105_RS02270	COG0737	Belongs to the 5'-nucleotidase family
YE105_RS02275	COG1218	3'(2'),5'-bisphosphate nucleotidase
YE105_RS02280	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YE105_RS02290	COG1253	flavin adenine dinucleotide binding
YE105_RS02295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YE105_RS02310	COG2105	PFAM AIG2 family protein
YE105_RS02315	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YE105_RS02325	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YE105_RS02330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YE105_RS02340	COG1438	arginine binding
YE105_RS02345	COG0039	L-malate dehydrogenase activity
YE105_RS02350	COG3423	Transcriptional regulator
YE105_RS02360	COG0142	geranyltranstransferase activity
YE105_RS02365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YE105_RS02370	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YE105_RS02375	COG0697	spore germination
YE105_RS02380	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YE105_RS02385	COG0642	Histidine kinase
YE105_RS02390	COG0745	RESPONSE REGULATOR receiver
YE105_RS02395	COG2027	D-alanyl-D-alanine carboxypeptidase
YE105_RS02405	COG1534	Rna-binding protein
YE105_RS02410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YE105_RS02420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YE105_RS02425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YE105_RS02430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YE105_RS02445	COG0779	Required for maturation of 30S ribosomal subunits
YE105_RS02450	COG0195	Participates in both transcription termination and antitermination
YE105_RS02455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YE105_RS02460	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YE105_RS02465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YE105_RS02470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YE105_RS02475	COG1185	polyribonucleotide nucleotidyltransferase activity
YE105_RS02485	COG0513	Belongs to the DEAD box helicase family
YE105_RS02495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YE105_RS02505	COG0814	amino acid
YE105_RS02510	COG3681	Belongs to the UPF0597 family
YE105_RS02515	COG0826	peptidase U32
YE105_RS02520	COG0826	peptidase U32
YE105_RS02525	COG3154	lipid carrier protein
YE105_RS02530	COG3153	acetyltransferase
YE105_RS02535	COG2827	Endonuclease containing a URI domain
YE105_RS02540	COG0531	amino acid
YE105_RS02545	COG1982	Orn Lys Arg decarboxylase major
YE105_RS02560	COG1653	transport
YE105_RS02565	COG1175	transmembrane transport
YE105_RS02570	COG0395	ABC-type sugar transport system, permease component
YE105_RS02575	COG3842	ATPase activity
YE105_RS02585	COG3787	Belongs to the UPF0306 family
YE105_RS02600	COG0702	epimerase
YE105_RS02605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YE105_RS02610	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YE105_RS02615	COG3454	Phosphonate metabolism
YE105_RS02620	COG4778	phosphonate C-P lyase system protein PhnL
YE105_RS02625	COG4107	phosphonate C-P lyase system protein PhnK
YE105_RS02630	COG3627	carbon phosphorus lyase activity
YE105_RS02635	COG3626	phosphonate metabolism
YE105_RS02640	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YE105_RS02645	COG3624	Phosphonate C-P lyase system protein PhnG
YE105_RS02650	COG2188	Transcriptional regulator
YE105_RS02680	COG4608	Belongs to the ABC transporter superfamily
YE105_RS02685	COG0444	Belongs to the ABC transporter superfamily
YE105_RS02690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_RS02695	COG0601	transmembrane transport
YE105_RS02705	COG2731	YhcH YjgK YiaL family protein
YE105_RS02715	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YE105_RS02730	COG2927	DNA polymerase III (CHI subunit)
YE105_RS02735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YE105_RS02740	COG0795	lipopolysaccharide-transporting ATPase activity
YE105_RS02745	COG0795	lipopolysaccharide-transporting ATPase activity
YE105_RS02800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YE105_RS02800	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
YE105_RS02805	COG0454	-acetyltransferase
YE105_RS02840	COG3328	transposase activity
YE105_RS02855	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YE105_RS02860	COG1830	Aldolase
YE105_RS02865	COG1879	ABC-type sugar transport system periplasmic component
YE105_RS02870	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS02880	COG1129	ABC transporter
YE105_RS02885	COG2390	Transcriptional regulator
YE105_RS02890	COG1070	Carbohydrate kinase
YE105_RS02895	COG0859	PFAM glycosyl transferase family 9
YE105_RS02910	COG2235	arginine
YE105_RS02915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS02920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_RS02930	COG2376	Dihydroxyacetone kinase
YE105_RS02935	COG1461	Dihydroxyacetone kinase
YE105_RS02940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS02940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YE105_RS02940	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
YE105_RS02950	COG2192	nodulation
YE105_RS02980	COG3284	Transcriptional regulator
YE105_RS03015	COG4772	TonB-dependent receptor
YE105_RS03040	COG0583	DNA-binding transcription factor activity
YE105_RS03045	COG0667	Aldo Keto reductase
YE105_RS03050	COG2813	Specifically methylates the guanine in position
YE105_RS03055	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YE105_RS03060	COG0456	acetyltransferase
YE105_RS03065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YE105_RS03070	COG2823	Periplasmic or secreted lipoprotein
YE105_RS03075	COG4667	esterase of the alpha-beta hydrolase superfamily
YE105_RS03080	COG0084	hydrolase, TatD family'
YE105_RS03085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YE105_RS03095	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YE105_RS03100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YE105_RS03105	COG0813	purine-nucleoside phosphorylase activity
YE105_RS03110	COG3726	membrane protein affecting hemolysin expression
YE105_RS03115	COG0560	Phosphoserine phosphatase
YE105_RS03130	COG0604	alcohol dehydrogenase
YE105_RS03145	COG0488	(ABC) transporter
YE105_RS03150	COG2885	chlorophyll binding
YE105_RS03155	COG2199	diguanylate cyclase activity
YE105_RS03165	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YE105_RS03170	COG0741	lytic transglycosylase activity
YE105_RS03175	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YE105_RS03180	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
YE105_RS03185	COG0406	alpha-ribazole phosphatase activity
YE105_RS03190	COG3708	Transcriptional regulator
YE105_RS03190	COG2207	Transcriptional regulator
YE105_RS03195	COG3045	CreA protein
YE105_RS03200	COG0745	RESPONSE REGULATOR receiver
YE105_RS03215	COG0083	homoserine kinase activity
YE105_RS03235	COG3022	response to hydroperoxide
YE105_RS03240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YE105_RS03245	COG0521	Mo-molybdopterin cofactor biosynthetic process
YE105_RS03260	COG1584	GPR1 FUN34 yaaH family protein
YE105_RS03265	COG0443	Heat shock 70 kDa protein
YE105_RS03270	COG0484	heat shock protein binding
YE105_RS03275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YE105_RS03280	COG0583	DNA-binding transcription factor activity
YE105_RS03285	COG0268	Binds directly to 16S ribosomal RNA
YE105_RS03295	COG0196	riboflavin kinase activity
YE105_RS03300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YE105_RS03305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YE105_RS03310	COG1047	Peptidyl-prolyl cis-trans
YE105_RS03315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YE105_RS03320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YE105_RS03330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YE105_RS03335	COG1280	lysine exporter protein (LysE YggA)
YE105_RS03340	COG2966	Psort location CytoplasmicMembrane, score
YE105_RS03345	COG3610	response to peptide
YE105_RS03350	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YE105_RS03355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YE105_RS03360	COG2967	ApaG domain
YE105_RS03365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YE105_RS03380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YE105_RS03385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YE105_RS03390	COG0564	pseudouridine synthase activity
YE105_RS03395	COG1470	cell adhesion involved in biofilm formation
YE105_RS03395	COG1388	LysM domain
YE105_RS03400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YE105_RS03405	COG0417	DNA replication proofreading
YE105_RS03410	COG0586	Pfam SNARE associated Golgi protein
YE105_RS03420	COG1178	ABC-type Fe3 transport system permease component
YE105_RS03425	COG4143	(ABC) transporter
YE105_RS03435	COG4533	DNA binding
YE105_RS03440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YE105_RS03445	COG1882	Formate acetyltransferase
YE105_RS03450	COG2814	Major facilitator Superfamily
YE105_RS03460	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YE105_RS03465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YE105_RS03470	COG0564	pseudouridine synthase activity
YE105_RS03480	COG0542	response to heat
YE105_RS03495	COG1605	Chorismate mutase
YE105_RS03495	COG0077	Prephenate dehydratase
YE105_RS03500	COG1605	Chorismate mutase
YE105_RS03500	COG0287	Prephenate dehydrogenase
YE105_RS03505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YE105_RS03510	COG3279	Response regulator of the LytR AlgR family
YE105_RS03515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YE105_RS03520	COG3137	Salt-induced outer membrane protein
YE105_RS03525	COG0335	large ribosomal subunit rRNA binding
YE105_RS03530	COG0336	Belongs to the RNA methyltransferase TrmD family
YE105_RS03535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YE105_RS03540	COG0228	four-way junction DNA binding
YE105_RS03545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YE105_RS03550	COG4137	Cytochrome C assembly protein
YE105_RS03555	COG4536	flavin adenine dinucleotide binding
YE105_RS03560	COG1854	S-ribosylhomocysteine lyase activity
YE105_RS03565	COG2918	glutathione biosynthetic process
YE105_RS03570	COG1238	metal cluster binding
YE105_RS03575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_RS03595	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YE105_RS03600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YE105_RS03605	COG2137	regulation of response to DNA damage stimulus
YE105_RS03610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YE105_RS03630	COG3381	protein complex oligomerization
YE105_RS03635	COG3302	dmso reductase anchor subunit
YE105_RS03640	COG0437	4 iron, 4 sulfur cluster binding
YE105_RS03645	COG0243	molybdopterin cofactor binding
YE105_RS03650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_RS03650	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_RS03665	COG4177	L-phenylalanine transmembrane transporter activity
YE105_RS03670	COG1137	ATPase activity
YE105_RS03730	COG0640	Transcriptional regulator
YE105_RS03735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YE105_RS03745	COG1858	cytochrome C peroxidase
YE105_RS03750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YE105_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS03780	COG1538	Outer membrane efflux protein
YE105_RS03790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS03820	COG3539	Fimbrial protein
YE105_RS03825	COG3539	Fimbrial protein
YE105_RS03835	COG3121	Chaperone
YE105_RS03840	COG3188	usher protein
YE105_RS03865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YE105_RS03870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YE105_RS03875	COG1388	LysM domain
YE105_RS03875	COG4942	peptidase
YE105_RS03880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YE105_RS03885	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YE105_RS03890	COG0585	pseudouridine synthase activity
YE105_RS03895	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YE105_RS03905	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YE105_RS03915	COG0529	Catalyzes the synthesis of activated sulfate
YE105_RS03920	COG2895	sulfate adenylyltransferase (ATP) activity
YE105_RS03925	COG0175	sulfate reduction
YE105_RS03930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YE105_RS03930	COG1648	precorrin-2 dehydrogenase activity
YE105_RS03935	COG2234	aminopeptidase activity
YE105_RS03950	COG0175	sulfate reduction
YE105_RS03955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YE105_RS03960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YE105_RS03965	COG0720	synthase
YE105_RS03990	COG0602	queuosine metabolic process
YE105_RS04025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YE105_RS04030	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YE105_RS04035	COG0583	DNA-binding transcription factor activity
YE105_RS04045	COG1279	arginine transmembrane transporter activity
YE105_RS04055	COG0814	amino acid
YE105_RS04060	COG3033	Beta-eliminating lyase
YE105_RS04075	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YE105_RS04080	COG0473	3-isopropylmalate dehydrogenase activity
YE105_RS04085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YE105_RS04095	COG1022	Amp-dependent synthetase and ligase
YE105_RS04100	COG0028	Belongs to the TPP enzyme family
YE105_RS04125	COG2001	Belongs to the MraZ family
YE105_RS04130	COG0275	rRNA processing
YE105_RS04135	COG3116	cell division
YE105_RS04140	COG0768	penicillin binding
YE105_RS04145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YE105_RS04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YE105_RS04155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YE105_RS04165	COG0772	Belongs to the SEDS family
YE105_RS04170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YE105_RS04175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YE105_RS04185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YE105_RS04190	COG0849	cell division
YE105_RS04195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YE105_RS04215	COG0653	protein targeting
YE105_RS04220	COG0494	nUDIX hydrolase
YE105_RS04225	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YE105_RS04240	COG0516	GMP reductase activity
YE105_RS04245	COG1459	type II secretion system
YE105_RS04250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YE105_RS04255	COG4969	Belongs to the N-Me-Phe pilin family
YE105_RS04270	COG3725	Membrane protein required for beta-lactamase induction
YE105_RS04275	COG1113	amino acid transport
YE105_RS04280	COG2186	Transcriptional regulator
YE105_RS04285	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YE105_RS04290	COG0508	dehydrogenase complex catalyzes the overall conversion of
YE105_RS04295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_RS04305	COG4977	sequence-specific DNA binding
YE105_RS04320	COG3112	Uncharacterised protein family (UPF0231)
YE105_RS04335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YE105_RS04340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YE105_RS04350	COG2132	Multicopper oxidase
YE105_RS04355	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YE105_RS04360	COG0288	reversible hydration of carbon dioxide
YE105_RS04365	COG1131	(ABC) transporter
YE105_RS04370	COG0842	Transport permease protein
YE105_RS04375	COG0726	polysaccharide deacetylase
YE105_RS04380	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YE105_RS04385	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YE105_RS04390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YE105_RS04395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YE105_RS04415	COG1489	DNA binding
YE105_RS04420	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YE105_RS04425	COG1643	Atp-dependent helicase
YE105_RS04430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YE105_RS04435	COG1120	ATPase activity
YE105_RS04440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YE105_RS04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_RS04455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YE105_RS04465	COG0316	Belongs to the HesB IscA family
YE105_RS04470	COG2860	membrane
YE105_RS04480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YE105_RS04485	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YE105_RS04490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YE105_RS04495	COG3850	Histidine kinase
YE105_RS04495	COG3437	response regulator, receiver
YE105_RS04495	COG2205	protein histidine kinase activity
YE105_RS04495	COG4999	Histidine kinase
YE105_RS04500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YE105_RS04505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YE105_RS04510	COG3956	TIGRFAM MazG family protein
YE105_RS04515	COG0504	CTP synthase activity
YE105_RS04520	COG0148	phosphopyruvate hydratase activity
YE105_RS04525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YE105_RS04530	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
YE105_RS04535	COG3079	Belongs to the UPF0149 family
YE105_RS04540	COG0006	proline dipeptidase activity
YE105_RS04545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YE105_RS04550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YE105_RS04555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YE105_RS04560	COG0509	glycine decarboxylation via glycine cleavage system
YE105_RS04565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YE105_RS04565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YE105_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS04585	COG1272	protein, Hemolysin III
YE105_RS04595	COG0354	folic acid binding
YE105_RS04610	COG0745	RESPONSE REGULATOR receiver
YE105_RS04615	COG2205	protein histidine kinase activity
YE105_RS04620	COG4452	Inner membrane protein CreD
YE105_RS04625	COG0716	FMN binding
YE105_RS04630	COG4974	Belongs to the 'phage' integrase family
YE105_RS04635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YE105_RS04640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YE105_RS04645	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
YE105_RS04650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YE105_RS04685	COG2944	sequence-specific DNA binding
YE105_RS04690	COG3328	transposase activity
YE105_RS04705	COG4319	ketosteroid isomerase
YE105_RS04710	COG3706	GGDEF domain
YE105_RS04725	COG1522	sequence-specific DNA binding
YE105_RS04740	COG2271	Major facilitator Superfamily
YE105_RS04755	COG0484	heat shock protein binding
YE105_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS04770	COG1733	regulation of RNA biosynthetic process
YE105_RS04775	COG0288	reversible hydration of carbon dioxide
YE105_RS04795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YE105_RS04805	COG2165	general secretion pathway protein
YE105_RS04835	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
YE105_RS04875	COG2814	Major facilitator Superfamily
YE105_RS04880	COG0583	DNA-binding transcription factor activity
YE105_RS04890	COG1609	Transcriptional regulator
YE105_RS04900	COG0204	Acyl-transferase
YE105_RS04900	COG0318	PFAM AMP-dependent synthetase and ligase
YE105_RS04905	COG0477	Major facilitator Superfamily
YE105_RS04910	COG0667	Aldo Keto reductase
YE105_RS04915	COG0861	Integral membrane protein TerC family
YE105_RS04920	COG3066	DNA modification
YE105_RS04930	COG1051	belongs to the nudix hydrolase family
YE105_RS04940	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YE105_RS04945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YE105_RS04950	COG2165	general secretion pathway protein
YE105_RS04975	COG1025	Belongs to the peptidase M16 family
YE105_RS04980	COG1074	ATP-dependent DNA helicase activity
YE105_RS04985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YE105_RS05000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YE105_RS05000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YE105_RS05005	COG0860	N-Acetylmuramoyl-L-alanine amidase
YE105_RS05025	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YE105_RS05030	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YE105_RS05035	COG2166	iron-sulfur cluster assembly
YE105_RS05040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YE105_RS05050	COG0583	DNA-binding transcription factor activity
YE105_RS05055	COG2363	Small membrane protein
YE105_RS05060	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
YE105_RS05075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS05080	COG1611	Belongs to the LOG family
YE105_RS05085	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YE105_RS05085	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YE105_RS05095	COG3098	single-species biofilm formation
YE105_RS05100	COG0564	pseudouridine synthase activity
YE105_RS05115	COG2171	N-acyltransferase activity
YE105_RS05120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YE105_RS05130	COG0052	Belongs to the universal ribosomal protein uS2 family
YE105_RS05135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YE105_RS05140	COG0528	UMP kinase activity
YE105_RS05145	COG0233	cytoplasmic translational termination
YE105_RS05150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YE105_RS05160	COG0575	Belongs to the CDS family
YE105_RS05165	COG0750	zinc metalloprotease
YE105_RS05175	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YE105_RS05180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_RS05185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YE105_RS05190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_RS05200	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YE105_RS05210	COG0825	malonyl-CoA metabolic process
YE105_RS05215	COG1982	Orn Lys Arg decarboxylase major
YE105_RS05220	COG0346	lactoylglutathione lyase activity
YE105_RS05235	COG4568	rho-dependent transcription termination
YE105_RS05245	COG4681	YaeQ
YE105_RS05255	COG3015	lipoprotein NlpE involved in copper resistance
YE105_RS05260	COG0442	prolyl-tRNA aminoacylation
YE105_RS05265	COG1720	tRNA m6t6A37 methyltransferase activity
YE105_RS05275	COG1464	Belongs to the NlpA lipoprotein family
YE105_RS05280	COG2011	ABC-type metal ion transport system permease component
YE105_RS05290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YE105_RS05315	COG5544	Lipoprotein
YE105_RS05320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YE105_RS05325	COG0045	succinate-CoA ligase (ADP-forming) activity
YE105_RS05325	COG1042	CoA-binding domain protein
YE105_RS05325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YE105_RS05330	COG3148	PFAM DTW domain containing protein
YE105_RS05335	COG3118	belongs to the thioredoxin family
YE105_RS05340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YE105_RS05355	COG2814	Major facilitator Superfamily
YE105_RS05360	COG1566	PFAM secretion protein HlyD family protein
YE105_RS05365	COG1538	Outer membrane efflux protein
YE105_RS05370	COG1846	Transcriptional regulator
YE105_RS05380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YE105_RS05385	COG2814	Major facilitator Superfamily
YE105_RS05425	COG0765	amino acid transport
YE105_RS05430	COG0765	amino acid transport
YE105_RS05440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YE105_RS05455	COG0436	Aminotransferase
YE105_RS05460	COG0235	Class ii aldolase
YE105_RS05465	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
YE105_RS05470	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YE105_RS05475	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YE105_RS05480	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
YE105_RS05495	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YE105_RS05500	COG1960	acyl-CoA dehydrogenase activity
YE105_RS05510	COG0121	glutamine amidotransferase
YE105_RS05515	COG3034	peptidoglycan biosynthetic process
YE105_RS05520	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_RS05525	COG1805	sodium ion transport
YE105_RS05530	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_RS05535	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_RS05540	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YE105_RS05545	COG2871	sodium ion transport
YE105_RS05550	COG1477	protein flavinylation
YE105_RS05555	COG2991	Protein conserved in bacteria
YE105_RS05565	COG1181	Belongs to the D-alanine--D-alanine ligase family
YE105_RS05570	COG2964	Protein conserved in bacteria
YE105_RS05585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YE105_RS05590	COG2195	Cleaves the N-terminal amino acid of tripeptides
YE105_RS05595	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YE105_RS05600	COG1073	alpha beta
YE105_RS05610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YE105_RS05615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YE105_RS05620	COG2188	Transcriptional regulator
YE105_RS05640	COG3459	Glycosyltransferase 36 associated
YE105_RS05655	COG2226	methyltransferase
YE105_RS05680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YE105_RS05685	COG3123	guanosine phosphorylase activity
YE105_RS05690	COG2974	May be involved in recombination
YE105_RS05695	COG1940	carbohydrate kinase activity
YE105_RS05710	COG0419	ATPase involved in DNA repair
YE105_RS05715	COG0420	3'-5' exonuclease activity
YE105_RS05720	COG0745	RESPONSE REGULATOR receiver
YE105_RS05725	COG5002	protein histidine kinase activity
YE105_RS05745	COG0366	Alpha amylase catalytic
YE105_RS05765	COG0450	alkyl hydroperoxide reductase
YE105_RS05770	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YE105_RS05775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YE105_RS05795	COG0343	queuine tRNA-ribosyltransferase activity
YE105_RS05800	COG1862	Preprotein translocase
YE105_RS05805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YE105_RS05810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YE105_RS05825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YE105_RS05830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YE105_RS05830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YE105_RS05835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YE105_RS05840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YE105_RS05845	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YE105_RS05850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YE105_RS05860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YE105_RS05865	COG0142	geranyltranstransferase activity
YE105_RS05875	COG0301	tRNA thio-modification
YE105_RS05875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YE105_RS05885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YE105_RS05890	COG1666	GTP binding
YE105_RS05895	COG2814	Major facilitator Superfamily
YE105_RS05900	COG0109	protoheme IX farnesyltransferase activity
YE105_RS05905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YE105_RS05910	COG1845	cytochrome c oxidase, subunit III
YE105_RS05915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YE105_RS05920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YE105_RS05930	COG2223	nitrite transmembrane transporter activity
YE105_RS05935	COG3056	Lipoprotein
YE105_RS05940	COG0271	Belongs to the BolA IbaG family
YE105_RS05950	COG0544	peptidyl-prolyl cis-trans isomerase activity
YE105_RS05955	COG0740	serine-type endopeptidase activity
YE105_RS05960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YE105_RS05965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YE105_RS05970	COG0776	regulation of translation
YE105_RS05975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YE105_RS05980	COG1555	photosystem II stabilization
YE105_RS05985	COG0824	Thioesterase
YE105_RS05990	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YE105_RS05995	COG4533	DNA binding
YE105_RS06000	COG0561	phosphatase activity
YE105_RS06010	COG1522	sequence-specific DNA binding
YE105_RS06015	COG1132	(ABC) transporter
YE105_RS06020	COG1132	(ABC) transporter
YE105_RS06025	COG0347	Belongs to the P(II) protein family
YE105_RS06030	COG0004	ammonium transporteR
YE105_RS06035	COG1946	Acyl-CoA thioesterase
YE105_RS06040	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YE105_RS06045	COG3695	enzyme binding
YE105_RS06070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_RS06075	COG0803	Belongs to the bacterial solute-binding protein 9 family
YE105_RS06080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YE105_RS06085	COG0254	rRNA binding
YE105_RS06100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YE105_RS06105	COG3457	Alanine racemase
YE105_RS06115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_RS06120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS06125	COG1309	transcriptional regulator
YE105_RS06130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YE105_RS06135	COG3264	Mechanosensitive ion channel
YE105_RS06135	COG1196	nuclear chromosome segregation
YE105_RS06150	COG2832	Protein of unknown function (DUF454)
YE105_RS06155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YE105_RS06165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YE105_RS06170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YE105_RS06175	COG0326	Molecular chaperone. Has ATPase activity
YE105_RS06180	COG0563	adenylate kinase activity
YE105_RS06185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YE105_RS06190	COG2244	polysaccharide biosynthetic process
YE105_RS06195	COG1216	Glycosyl transferase, family 2
YE105_RS06195	COG1442	glycosyl transferase family 8
YE105_RS06200	COG1215	transferase activity, transferring glycosyl groups
YE105_RS06205	COG0438	transferase activity, transferring glycosyl groups
YE105_RS06210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YE105_RS06215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YE105_RS06235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_RS06240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YE105_RS06240	COG4651	solute:proton antiporter activity
YE105_RS06245	COG2223	nitrite transmembrane transporter activity
YE105_RS06250	COG0737	Belongs to the 5'-nucleotidase family
YE105_RS06260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YE105_RS06265	COG3735	TraB family
YE105_RS06270	COG2217	Heavy metal translocating P-type atpase
YE105_RS06275	COG0789	Transcriptional regulator
YE105_RS06280	COG1585	Membrane protein implicated in regulation of membrane protease activity
YE105_RS06285	COG0330	HflC and HflK could
YE105_RS06290	COG3118	belongs to the thioredoxin family
YE105_RS06295	COG0300	oxidoreductase activity
YE105_RS06300	COG2755	lipolytic protein G-D-S-L family
YE105_RS06305	COG4181	ATPase activity
YE105_RS06310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YE105_RS06315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YE105_RS06320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YE105_RS06325	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YE105_RS06330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YE105_RS06335	COG0215	cysteine-tRNA ligase activity
YE105_RS06340	COG2501	S4 domain
YE105_RS06345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YE105_RS06355	COG0582	viral genome integration into host DNA
YE105_RS06395	COG2850	peptidyl-arginine hydroxylation
YE105_RS06400	COG2986	histidine ammonia-lyase
YE105_RS06415	COG5265	(ABC) transporter
YE105_RS06430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YE105_RS06440	COG2197	response regulator
YE105_RS06445	COG1278	Cold shock
YE105_RS06460	COG3706	GGDEF domain
YE105_RS06465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YE105_RS06470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YE105_RS06475	COG0321	lipoyl(octanoyl) transferase activity
YE105_RS06480	COG2921	Belongs to the UPF0250 family
YE105_RS06485	COG1686	Belongs to the peptidase S11 family
YE105_RS06490	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YE105_RS06495	COG0772	Belongs to the SEDS family
YE105_RS06500	COG0768	penicillin binding
YE105_RS06510	COG0799	negative regulation of ribosome biogenesis
YE105_RS06515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YE105_RS06520	COG1466	dna polymerase III delta subunit
YE105_RS06525	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
YE105_RS06530	COG0495	leucyl-tRNA aminoacylation
YE105_RS06535	COG2888	peptidyl-tyrosine sulfation
YE105_RS06540	COG1126	abc transporter atp-binding protein
YE105_RS06545	COG0765	amino acid transport
YE105_RS06550	COG0765	amino acid transport
YE105_RS06565	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YE105_RS06570	COG4535	Mg2 and Co2 transporter CorC
YE105_RS06575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YE105_RS06580	COG1702	phosphate starvation-inducible protein PhoH
YE105_RS06585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YE105_RS06590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YE105_RS06625	COG0367	asparagine synthase
YE105_RS06630	COG0647	UMP catabolic process
YE105_RS06635	COG1846	Transcriptional regulator
YE105_RS06635	COG1940	carbohydrate kinase activity
YE105_RS06640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YE105_RS06645	COG0363	glucosamine-6-phosphate deaminase activity
YE105_RS06650	COG1263	PTS System
YE105_RS06650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS06650	COG2190	(PTS) system
YE105_RS06655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YE105_RS06675	COG0735	belongs to the Fur family
YE105_RS06685	COG0840	transmembrane signaling receptor activity
YE105_RS06695	COG0596	Alpha beta hydrolase
YE105_RS06700	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YE105_RS06705	COG0033	Phosphoglucomutase
YE105_RS06720	COG0745	RESPONSE REGULATOR receiver
YE105_RS06725	COG2205	protein histidine kinase activity
YE105_RS06730	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YE105_RS06735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YE105_RS06740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YE105_RS06760	COG2994	toxin metabolic process
YE105_RS06775	COG3272	Protein of unknown function (DUF1722)
YE105_RS06785	COG5212	phosphodiesterase
YE105_RS06790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YE105_RS06795	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YE105_RS06800	COG1984	allophanate hydrolase subunit 2
YE105_RS06805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YE105_RS06820	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YE105_RS06830	COG2009	succinate dehydrogenase
YE105_RS06835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YE105_RS06840	COG1053	succinate dehydrogenase
YE105_RS06850	COG0567	Dehydrogenase, E1 component
YE105_RS06855	COG0508	dehydrogenase complex catalyzes the overall conversion of
YE105_RS06860	COG0045	succinate-CoA ligase (ADP-forming) activity
YE105_RS06865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YE105_RS06875	COG1271	oxidase subunit
YE105_RS06880	COG1294	oxidase, subunit
YE105_RS06885	COG4890	Cyd operon protein YbgT
YE105_RS06890	COG3790	cyd operon protein YbgE
YE105_RS06895	COG0824	Thioesterase
YE105_RS06900	COG0811	peptide transport
YE105_RS06905	COG0848	biopolymer transport protein
YE105_RS06910	COG3064	Membrane
YE105_RS06910	COG3064	Membrane
YE105_RS06915	COG0823	Involved in the tonB-independent uptake of proteins
YE105_RS06920	COG2885	chlorophyll binding
YE105_RS06925	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YE105_RS06940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YE105_RS06950	COG1230	cation diffusion facilitator family transporter
YE105_RS06955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YE105_RS06960	COG0588	phosphoglycerate mutase activity
YE105_RS06985	COG2017	converts alpha-aldose to the beta-anomer
YE105_RS06990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
YE105_RS06995	COG1085	galactose-1-phosphate uridylyltransferase
YE105_RS07000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YE105_RS07010	COG1119	ATPase activity
YE105_RS07015	COG2005	Transcriptional regulator
YE105_RS07015	COG3585	molybdate ion transport
YE105_RS07025	COG0725	ABC transporter, periplasmic molybdate-binding protein
YE105_RS07030	COG0582	viral genome integration into host DNA
YE105_RS07210	COG3772	lysozyme
YE105_RS07220	COG4149	molybdate abc transporter
YE105_RS07230	COG0561	phosphatase activity
YE105_RS07235	COG2706	6-phosphogluconolactonase activity
YE105_RS07245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YE105_RS07250	COG0156	8-amino-7-oxononanoate synthase activity
YE105_RS07255	COG2226	methyltransferase
YE105_RS07270	COG0556	nucleotide-excision repair
YE105_RS07275	COG4628	conserved protein (DUF2132)
YE105_RS07280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YE105_RS07285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YE105_RS07290	COG0315	cyclic pyranopterin monophosphate synthase activity
YE105_RS07295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YE105_RS07300	COG0314	molybdopterin synthase activity
YE105_RS07305	COG0670	Belongs to the BI1 family
YE105_RS07310	COG0842	Transport permease protein
YE105_RS07315	COG0842	Transport permease protein
YE105_RS07320	COG1131	(ABC) transporter
YE105_RS07325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS07330	COG1309	transcriptional regulator
YE105_RS07335	COG0513	Belongs to the DEAD box helicase family
YE105_RS07340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YE105_RS07350	COG2239	Acts as a magnesium transporter
YE105_RS07360	COG1686	Belongs to the peptidase S11 family
YE105_RS07365	COG0277	FAD linked oxidase domain protein
YE105_RS07385	COG2261	transglycosylase associated protein
YE105_RS07395	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YE105_RS07410	COG4807	Protein conserved in bacteria
YE105_RS07430	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YE105_RS07440	COG2897	thiosulfate sulfurtransferase activity
YE105_RS07455	COG1732	Glycine betaine
YE105_RS07460	COG1174	glycine betaine transport
YE105_RS07465	COG1125	glycine betaine transport
YE105_RS07470	COG1174	glycine betaine transport
YE105_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS07485	COG0583	DNA-binding transcription factor activity
YE105_RS07495	COG0697	spore germination
YE105_RS07515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YE105_RS07520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YE105_RS07540	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
YE105_RS07550	COG1126	abc transporter atp-binding protein
YE105_RS07555	COG0765	amino acid transport
YE105_RS07560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS07565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YE105_RS07570	COG0783	Belongs to the Dps family
YE105_RS07575	COG4106	trans-aconitate 2-methyltransferase activity
YE105_RS07590	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
YE105_RS07610	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YE105_RS07630	COG0488	(ABC) transporter
YE105_RS07640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YE105_RS07645	COG0303	'Molybdopterin
YE105_RS07660	COG0577	efflux transmembrane transporter activity
YE105_RS07660	COG1136	(ABC) transporter
YE105_RS07690	COG0583	DNA-binding transcription factor activity
YE105_RS07695	COG0477	Major facilitator Superfamily
YE105_RS07700	COG0302	gtp cyclohydrolase
YE105_RS07705	COG2311	Membrane
YE105_RS07730	COG3604	Transcriptional regulator
YE105_RS07735	COG3383	formate dehydrogenase (NAD+) activity
YE105_RS07740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YE105_RS07745	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YE105_RS07755	COG3260	NADH ubiquinone oxidoreductase 20
YE105_RS07760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS07765	COG3261	NADH dehydrogenase
YE105_RS07765	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
YE105_RS07770	COG0651	ATP synthesis coupled electron transport
YE105_RS07775	COG4237	Hydrogenase 4 membrane
YE105_RS07780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YE105_RS07785	COG0650	Formate hydrogenlyase subunit 4
YE105_RS07790	COG0651	ATP synthesis coupled electron transport
YE105_RS07795	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YE105_RS07800	COG0375	protein maturation
YE105_RS07805	COG0298	carbon dioxide binding
YE105_RS07810	COG2949	membrane
YE105_RS07815	COG0281	malic enzyme
YE105_RS07830	COG1346	cytolysis
YE105_RS07835	COG1380	Effector of murein hydrolase LrgA
YE105_RS07840	COG2814	Major facilitator Superfamily
YE105_RS07865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YE105_RS07865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YE105_RS07870	COG0489	protein tyrosine kinase activity
YE105_RS07875	COG0572	uridine kinase
YE105_RS07885	COG2982	Protein involved in outer membrane biogenesis
YE105_RS07890	COG3069	C4-dicarboxylate transmembrane transporter activity
YE105_RS07895	COG1253	flavin adenine dinucleotide binding
YE105_RS07910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YE105_RS07915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YE105_RS07920	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YE105_RS07925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YE105_RS07950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YE105_RS07960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YE105_RS07965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YE105_RS07965	COG0140	phosphoribosyl-ATP diphosphatase activity
YE105_RS07970	COG0107	imidazoleglycerol-phosphate synthase activity
YE105_RS07975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YE105_RS07985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YE105_RS07985	COG0131	Imidazoleglycerol-phosphate dehydratase
YE105_RS07990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YE105_RS08000	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YE105_RS08005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_RS08015	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS08020	COG1129	ABC transporter
YE105_RS08035	COG0531	amino acid
YE105_RS08040	COG2925	Exonuclease
YE105_RS08045	COG1022	Amp-dependent synthetase and ligase
YE105_RS08045	COG3320	Male sterility
YE105_RS08050	COG1289	transmembrane transporter activity
YE105_RS08055	COG2926	Belongs to the UPF0265 family
YE105_RS08065	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS08070	COG1129	ABC transporter
YE105_RS08085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YE105_RS08095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YE105_RS08115	COG4656	Part of a membrane complex involved in electron transport
YE105_RS08125	COG1012	belongs to the aldehyde dehydrogenase family
YE105_RS08135	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
YE105_RS08210	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YE105_RS08220	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
YE105_RS08285	COG1492	cobalamin metabolic process
YE105_RS08305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YE105_RS08375	COG3121	Chaperone
YE105_RS08380	COG3188	usher protein
YE105_RS08450	COG0137	argininosuccinate synthase activity
YE105_RS08455	COG0534	Mate efflux family protein
YE105_RS08465	COG0352	thiamine-phosphate diphosphorylase activity
YE105_RS08470	COG0561	phosphatase activity
YE105_RS08475	COG1349	DNA-binding transcription factor activity
YE105_RS08485	COG0784	Response regulator, receiver
YE105_RS08485	COG0835	chemotaxis
YE105_RS08495	COG4221	oxidoreductase activity
YE105_RS08515	COG3842	ATPase activity
YE105_RS08525	COG1840	ABC-type Fe3 transport system, periplasmic component
YE105_RS08530	COG2271	Major facilitator Superfamily
YE105_RS08545	COG4565	transcriptional regulatory protein
YE105_RS08550	COG3290	protein histidine kinase activity
YE105_RS08555	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
YE105_RS08560	COG3052	prosthetic group binding
YE105_RS08565	COG2301	Belongs to the HpcH HpaI aldolase family
YE105_RS08570	COG3051	citrate lyase alpha subunit
YE105_RS08575	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
YE105_RS08575	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
YE105_RS08585	COG0471	metal ion transport
YE105_RS08600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YE105_RS08620	COG2814	Major facilitator Superfamily
YE105_RS08625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS08625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS08630	COG3122	Protein conserved in bacteria
YE105_RS08650	COG3121	Chaperone
YE105_RS08675	COG2205	protein histidine kinase activity
YE105_RS08675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS08690	COG3228	Belongs to the MtfA family
YE105_RS08700	COG1070	Carbohydrate kinase
YE105_RS08725	COG3121	Chaperone
YE105_RS08765	COG0604	alcohol dehydrogenase
YE105_RS08765	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS08765	COG3321	synthase
YE105_RS08775	COG3250	beta-galactosidase activity
YE105_RS08780	COG1609	Transcriptional regulator
YE105_RS08795	COG0840	transmembrane signaling receptor activity
YE105_RS08810	COG1285	pathogenesis
YE105_RS08820	COG2130	NADP-dependent
YE105_RS08825	COG0589	response to stress
YE105_RS08845	COG1360	Flagellar Motor Protein
YE105_RS08850	COG0643	Histidine kinase
YE105_RS08850	COG2198	Histidine kinase
YE105_RS08855	COG0835	chemotaxis
YE105_RS08860	COG0840	transmembrane signaling receptor activity
YE105_RS08865	COG0840	transmembrane signaling receptor activity
YE105_RS08870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YE105_RS08880	COG0745	RESPONSE REGULATOR receiver
YE105_RS08885	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YE105_RS08890	COG4935	Belongs to the peptidase S8 family
YE105_RS08890	COG1404	Belongs to the peptidase S8 family
YE105_RS08895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YE105_RS08900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YE105_RS08915	COG3418	PFAM FlgN family protein
YE105_RS08920	COG2747	anti-sigma28 factor FlgM
YE105_RS08930	COG1815	bacterial-type flagellum-dependent cell motility
YE105_RS08935	COG1558	bacterial-type flagellum-dependent cell motility
YE105_RS08940	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YE105_RS08975	COG1256	bacterial-type flagellum assembly
YE105_RS08995	COG1338	Plays a role in the flagellum-specific transport system
YE105_RS09015	COG1580	Controls the rotational direction of flagella during chemotaxis
YE105_RS09035	COG1317	bacterial-type flagellum organization
YE105_RS09050	COG1677	Flagellar hook-basal body complex protein FliE
YE105_RS09085	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YE105_RS09090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YE105_RS09135	COG1191	sigma factor activity
YE105_RS09145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YE105_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS09155	COG0765	amino acid transport
YE105_RS09160	COG1126	abc transporter atp-binding protein
YE105_RS09175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YE105_RS09175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YE105_RS09175	COG0506	proline dehydrogenase activity
YE105_RS09190	COG3157	Type VI secretion system effector, Hcp
YE105_RS09200	COG0672	)-iron permease
YE105_RS09205	COG2822	iron ion transport
YE105_RS09215	COG0655	NAD(P)H dehydrogenase (quinone) activity
YE105_RS09225	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
YE105_RS09240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YE105_RS09245	COG0778	Nitroreductase
YE105_RS09250	COG2267	carboxylic ester hydrolase activity
YE105_RS09255	COG0251	oxidation-reduction process
YE105_RS09260	COG1335	isochorismatase
YE105_RS09265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YE105_RS09270	COG1309	transcriptional regulator
YE105_RS09275	COG1113	amino acid transport
YE105_RS09285	COG0582	viral genome integration into host DNA
YE105_RS09290	COG2963	transposase activity
YE105_RS09300	COG2226	methyltransferase
YE105_RS09315	COG0366	Alpha amylase catalytic
YE105_RS09325	COG3136	membrane protein required for alginate biosynthesis
YE105_RS09335	COG2197	response regulator
YE105_RS09340	COG0322	excinuclease ABC activity
YE105_RS09345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YE105_RS09430	COG3077	Addiction module antitoxin, RelB DinJ family
YE105_RS09435	COG3041	Addiction module toxin RelE StbE family
YE105_RS09525	COG2963	transposase activity
YE105_RS09535	COG3328	transposase activity
YE105_RS09585	COG3772	lysozyme
YE105_RS09590	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YE105_RS09595	COG2979	Protein of unknown function (DUF533)
YE105_RS09610	COG0012	GTP binding
YE105_RS09620	COG0193	aminoacyl-tRNA hydrolase activity
YE105_RS09635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YE105_RS09645	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
YE105_RS09650	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YE105_RS09655	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YE105_RS09660	COG2890	protein-(glutamine-N5) methyltransferase activity
YE105_RS09675	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YE105_RS09680	COG0659	secondary active sulfate transmembrane transporter activity
YE105_RS09685	COG3706	GGDEF domain
YE105_RS09705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YE105_RS09710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YE105_RS09715	COG3381	protein complex oligomerization
YE105_RS09725	COG0477	Major facilitator Superfamily
YE105_RS09740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YE105_RS09750	COG0673	inositol 2-dehydrogenase activity
YE105_RS09755	COG0728	peptidoglycan biosynthetic process
YE105_RS09760	COG0387	Pfam Sodium calcium exchanger
YE105_RS09775	COG0583	DNA-binding transcription factor activity
YE105_RS09780	COG3850	Histidine kinase
YE105_RS09785	COG1294	oxidase, subunit
YE105_RS09790	COG1271	oxidase subunit
YE105_RS09795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_RS09800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YE105_RS09805	COG3138	arginine N-succinyltransferase
YE105_RS09815	COG3724	N-succinylarginine dihydrolase activity
YE105_RS09820	COG2988	succinylglutamate desuccinylase activity
YE105_RS09845	COG1228	amidohydrolase
YE105_RS09855	COG0402	S-adenosylhomocysteine deaminase activity
YE105_RS09865	COG3443	Belongs to the bacterial solute-binding protein 9 family
YE105_RS09890	COG4942	peptidase
YE105_RS09900	COG2222	sugar isomerase
YE105_RS09905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS09910	COG3716	PTS system mannose fructose sorbose family IID component
YE105_RS09920	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS09930	COG1349	DNA-binding transcription factor activity
YE105_RS09950	COG1187	pseudouridine synthase activity
YE105_RS09955	COG0786	glutamate:sodium symporter activity
YE105_RS09975	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YE105_RS09980	COG2226	methyltransferase
YE105_RS09985	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YE105_RS09990	COG1801	Protein of unknown function DUF72
YE105_RS09995	COG1335	isochorismatase
YE105_RS10005	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YE105_RS10010	COG0494	nUDIX hydrolase
YE105_RS10015	COG0217	transcriptional regulatory protein
YE105_RS10020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YE105_RS10025	COG0632	four-way junction helicase activity
YE105_RS10030	COG2255	four-way junction helicase activity
YE105_RS10035	COG3104	oligopeptide transport
YE105_RS10040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_RS10045	COG1121	(ABC) transporter
YE105_RS10050	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YE105_RS10055	COG0739	heme binding
YE105_RS10060	COG1560	Kdo2-lipid A biosynthetic process
YE105_RS10075	COG3328	transposase activity
YE105_RS10080	COG0469	pyruvate kinase activity
YE105_RS10085	COG1737	Transcriptional regulator
YE105_RS10090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YE105_RS10095	COG0800	Aldolase
YE105_RS10100	COG2076	Multidrug Resistance protein
YE105_RS10105	COG2076	Multidrug Resistance protein
YE105_RS10110	COG0251	oxidation-reduction process
YE105_RS10115	COG1199	ATP-dependent helicase activity
YE105_RS10125	COG3065	identical protein binding
YE105_RS10130	COG0318	PFAM AMP-dependent synthetase and ligase
YE105_RS10135	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YE105_RS10140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YE105_RS10145	COG2894	cell division
YE105_RS10150	COG0850	regulation of cytokinetic process
YE105_RS10160	COG3100	YcgL domain-containing protein
YE105_RS10165	COG2951	lytic endotransglycosylase activity
YE105_RS10170	COG0179	Fumarylacetoacetate (FAA) hydrolase
YE105_RS10175	COG2983	Belongs to the UPF0260 family
YE105_RS10205	COG0668	transmembrane transport
YE105_RS10210	COG0625	glutathione transferase activity
YE105_RS10235	COG2203	Gaf domain
YE105_RS10235	COG3706	GGDEF domain
YE105_RS10235	COG4251	negative regulation of phosphorylation
YE105_RS10235	COG5001	Diguanylate cyclase
YE105_RS10270	COG2814	Major facilitator Superfamily
YE105_RS10280	COG3008	intermembrane lipid transfer
YE105_RS10285	COG2995	paraquat-inducible protein a
YE105_RS10290	COG1956	GAF domain-containing protein
YE105_RS10300	COG0793	Belongs to the peptidase S41A family
YE105_RS10305	COG0501	Belongs to the peptidase M48B family
YE105_RS10315	COG2814	Major facilitator Superfamily
YE105_RS10320	COG0823	Involved in the tonB-independent uptake of proteins
YE105_RS10330	COG3023	N-Acetylmuramoyl-L-alanine amidase
YE105_RS10335	COG1823	symporter activity
YE105_RS10340	COG1988	membrane-bound metal-dependent
YE105_RS10350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YE105_RS10355	COG1653	transport
YE105_RS10360	COG3842	ATPase activity
YE105_RS10365	COG0395	ABC-type sugar transport system, permease component
YE105_RS10370	COG1175	transmembrane transport
YE105_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS10385	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
YE105_RS10390	COG1917	Cupin 2, conserved barrel domain protein
YE105_RS10395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_RS10405	COG0583	DNA-binding transcription factor activity
YE105_RS10410	COG0427	acetyl-CoA hydrolase
YE105_RS10415	COG1024	Enoyl-CoA hydratase
YE105_RS10420	COG1703	isobutyryl-CoA mutase activity
YE105_RS10425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YE105_RS10425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YE105_RS10430	COG3001	Fructosamine kinase
YE105_RS10435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_RS10440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YE105_RS10445	COG1121	(ABC) transporter
YE105_RS10450	COG0803	Belongs to the bacterial solute-binding protein 9 family
YE105_RS10485	COG1811	Na channel or pump
YE105_RS10490	COG4249	Peptidase C14 caspase catalytic subunit p20
YE105_RS10495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YE105_RS10500	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YE105_RS10505	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YE105_RS10510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YE105_RS10515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YE105_RS10525	COG0776	regulation of translation
YE105_RS10540	COG4139	cobalamin transport
YE105_RS10545	COG0386	Belongs to the glutathione peroxidase family
YE105_RS10550	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YE105_RS10555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YE105_RS10560	COG0463	Glycosyl transferase, family 2
YE105_RS10565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YE105_RS10565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_RS10570	COG0726	polysaccharide deacetylase
YE105_RS10575	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YE105_RS10580	COG2076	Multidrug Resistance protein
YE105_RS10585	COG2076	Multidrug Resistance protein
YE105_RS10590	COG0791	NLP P60 protein
YE105_RS10595	COG0095	Lipoate-protein ligase
YE105_RS10605	COG4558	Periplasmic binding protein
YE105_RS10610	COG3720	iron ion transport
YE105_RS10630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YE105_RS10635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YE105_RS10635	COG0574	Belongs to the PEP-utilizing enzyme family
YE105_RS10640	COG0628	permease
YE105_RS10645	COG0247	lactate metabolic process
YE105_RS10645	COG0277	FAD linked oxidase domain protein
YE105_RS10650	COG2050	protein possibly involved in aromatic compounds catabolism
YE105_RS10655	COG0316	Belongs to the HesB IscA family
YE105_RS10660	COG0719	Fe-S assembly protein
YE105_RS10665	COG0396	ATPase activity
YE105_RS10670	COG0719	Fe-S assembly protein
YE105_RS10680	COG2166	iron-sulfur cluster assembly
YE105_RS10685	COG1376	ErfK ybiS ycfS ynhG family protein
YE105_RS10685	COG1388	LysM domain
YE105_RS10710	COG0534	Mate efflux family protein
YE105_RS10715	COG0307	riboflavin synthase, alpha
YE105_RS10720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YE105_RS10725	COG2814	Major facilitator Superfamily
YE105_RS10730	COG0583	DNA-binding transcription factor activity
YE105_RS10735	COG1609	Transcriptional regulator
YE105_RS10745	COG0791	NLP P60 protein
YE105_RS10750	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YE105_RS10755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YE105_RS10760	COG0346	lactoylglutathione lyase activity
YE105_RS10765	COG1902	pentaerythritol trinitrate reductase activity
YE105_RS10770	COG1309	transcriptional regulator
YE105_RS10775	COG2194	sulfuric ester hydrolase activity
YE105_RS10780	COG3313	Fe-S protein
YE105_RS10785	COG4989	oxidoreductase activity
YE105_RS10790	COG1289	transmembrane transporter activity
YE105_RS10795	COG1566	PFAM secretion protein HlyD family protein
YE105_RS10805	COG1846	Transcriptional regulator
YE105_RS10810	COG3133	Outer membrane lipoprotein
YE105_RS10815	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YE105_RS10820	COG3895	Periplasmic Protein
YE105_RS10825	COG0259	pyridoxamine-phosphate oxidase activity
YE105_RS10830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YE105_RS10840	COG0625	glutathione transferase activity
YE105_RS10860	COG3104	oligopeptide transport
YE105_RS10880	COG4172	Belongs to the ABC transporter superfamily
YE105_RS10890	COG4171	peptide transport system, permease
YE105_RS10895	COG4168	peptide transport system, permease
YE105_RS10900	COG4166	transmembrane transport
YE105_RS10920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YE105_RS10925	COG1842	Phage shock protein A
YE105_RS10935	COG1983	PspC domain protein
YE105_RS10945	COG3106	COG3106 Predicted ATPase
YE105_RS10950	COG3768	UPF0283 membrane protein
YE105_RS10955	COG5654	RES domain protein
YE105_RS10960	COG5642	Protein of unknown function (DUF2384)
YE105_RS10970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YE105_RS10975	COG4948	Mandelate Racemase Muconate Lactonizing
YE105_RS10980	COG2866	Carboxypeptidase
YE105_RS10985	COG4166	transmembrane transport
YE105_RS10990	COG0598	Magnesium transport protein CorA
YE105_RS10995	COG0037	tRNA processing
YE105_RS11000	COG0823	Involved in the tonB-independent uptake of proteins
YE105_RS11005	COG1013	pyruvate-flavodoxin oxidoreductase activity
YE105_RS11005	COG0674	pyruvate-flavodoxin oxidoreductase activity
YE105_RS11005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YE105_RS11005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS11015	COG1285	pathogenesis
YE105_RS11020	COG3042	response to heat
YE105_RS11025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YE105_RS11030	COG2911	Protein conserved in bacteria
YE105_RS11040	COG3784	Protein of unknown function (DUF1318)
YE105_RS11045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YE105_RS11050	COG1643	Atp-dependent helicase
YE105_RS11065	COG3591	Belongs to the peptidase S1B family
YE105_RS11075	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YE105_RS11080	COG2205	protein histidine kinase activity
YE105_RS11085	COG0745	RESPONSE REGULATOR receiver
YE105_RS11095	COG0531	amino acid
YE105_RS11110	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YE105_RS11115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YE105_RS11120	COG0589	response to stress
YE105_RS11125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YE105_RS11130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YE105_RS11145	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
YE105_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS11160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_RS11165	COG0738	Major facilitator superfamily
YE105_RS11180	COG1011	Hydrolase
YE105_RS11185	COG0440	acetolactate synthase activity
YE105_RS11190	COG0028	Belongs to the TPP enzyme family
YE105_RS11200	COG3023	N-Acetylmuramoyl-L-alanine amidase
YE105_RS11220	COG2271	Major facilitator Superfamily
YE105_RS11225	COG0483	inositol monophosphate 1-phosphatase activity
YE105_RS11235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YE105_RS11250	COG3177	Filamentation induced by cAMP protein fic
YE105_RS11280	COG4215	(ABC) transporter
YE105_RS11290	COG1522	sequence-specific DNA binding
YE105_RS11320	COG0625	glutathione transferase activity
YE105_RS11490	COG4221	oxidoreductase activity
YE105_RS11495	COG1742	UPF0060 membrane protein
YE105_RS11525	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YE105_RS11530	COG1940	carbohydrate kinase activity
YE105_RS11535	COG0583	DNA-binding transcription factor activity
YE105_RS11540	COG2814	Major facilitator Superfamily
YE105_RS11565	COG0114	fumarate hydratase activity
YE105_RS11575	COG5339	Protein conserved in bacteria
YE105_RS11585	COG1609	Transcriptional regulator
YE105_RS11590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS11590	COG1263	PTS System
YE105_RS11595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YE105_RS11600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YE105_RS11605	COG0385	Bile acid
YE105_RS11610	COG0673	inositol 2-dehydrogenase activity
YE105_RS11620	COG1172	Belongs to the binding-protein-dependent transport system permease family
YE105_RS11625	COG1129	ABC transporter
YE105_RS11630	COG1879	ABC-type sugar transport system periplasmic component
YE105_RS11640	COG2160	L-arabinose isomerase activity
YE105_RS11645	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YE105_RS11650	COG2274	protein secretion by the type I secretion system
YE105_RS11665	COG2759	Belongs to the formate--tetrahydrofolate ligase family
YE105_RS11675	COG4657	Part of a membrane complex involved in electron transport
YE105_RS11685	COG4656	Part of a membrane complex involved in electron transport
YE105_RS11695	COG2207	Transcriptional regulator
YE105_RS11695	COG3708	Transcriptional regulator
YE105_RS11700	COG4658	electron transport chain
YE105_RS11705	COG4659	FMN binding
YE105_RS11715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YE105_RS11740	COG0243	molybdopterin cofactor binding
YE105_RS11745	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YE105_RS11750	COG1966	Carbon starvation protein
YE105_RS11755	COG2879	small protein
YE105_RS11760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YE105_RS11765	COG1349	DNA-binding transcription factor activity
YE105_RS11790	COG0023	Translation Initiation Factor
YE105_RS11795	COG0284	orotidine-5'-phosphate decarboxylase activity
YE105_RS11805	COG3135	benzoate transporter
YE105_RS11810	COG1396	sequence-specific DNA binding
YE105_RS11820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YE105_RS11825	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YE105_RS11830	COG0671	phosphoesterase, PA-phosphatase related
YE105_RS11855	COG0583	DNA-binding transcription factor activity
YE105_RS11870	COG0616	signal peptide processing
YE105_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS11880	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YE105_RS11890	COG1187	pseudouridine synthase activity
YE105_RS11895	COG0009	L-threonylcarbamoyladenylate synthase
YE105_RS11900	COG0613	PHP domain protein
YE105_RS11910	COG0512	Glutamine amidotransferase of anthranilate synthase
YE105_RS11920	COG0135	phosphoribosylanthranilate isomerase activity
YE105_RS11920	COG0134	indole-3-glycerol-phosphate synthase activity
YE105_RS11925	COG0133	tryptophan synthase activity
YE105_RS11930	COG0159	tryptophan synthase activity
YE105_RS11940	COG3047	cAMP biosynthetic process
YE105_RS11945	COG0727	PFAM Uncharacterised protein family (UPF0153)
YE105_RS11960	COG2917	probably involved in intracellular septation
YE105_RS11965	COG1607	acyl-coa hydrolase
YE105_RS11970	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YE105_RS11975	COG2350	Protein conserved in bacteria
YE105_RS11990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YE105_RS11995	COG3099	Belongs to the UPF0263 family
YE105_RS12005	COG0444	Belongs to the ABC transporter superfamily
YE105_RS12010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_RS12030	COG2095	MarC family integral membrane protein
YE105_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
YE105_RS12035	COG1454	alcohol dehydrogenase
YE105_RS12050	COG2916	Histone family protein nucleoid-structuring protein H-NS
YE105_RS12060	COG0745	RESPONSE REGULATOR receiver
YE105_RS12065	COG1752	Esterase of the alpha-beta hydrolase superfamily
YE105_RS12075	COG3012	SEC-C Motif Domain Protein
YE105_RS12080	COG0788	formyltetrahydrofolate deformylase activity
YE105_RS12095	COG0583	DNA-binding transcription factor activity
YE105_RS12100	COG0708	Exodeoxyribonuclease III
YE105_RS12105	COG0494	nUDIX hydrolase
YE105_RS12115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YE105_RS12125	COG0778	Nitroreductase
YE105_RS12130	COG0616	signal peptide processing
YE105_RS12135	COG0252	asparaginase activity
YE105_RS12140	COG1335	isochorismatase
YE105_RS12150	COG3139	Protein of unknown function (DUF1315)
YE105_RS12155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YE105_RS12170	COG3713	MltA-interacting MipA family protein
YE105_RS12175	COG2766	serine protein kinase
YE105_RS12180	COG2718	Belongs to the UPF0229 family
YE105_RS12195	COG0583	DNA-binding transcription factor activity
YE105_RS12205	COG2200	EAL domain
YE105_RS12205	COG2202	Pas domain
YE105_RS12205	COG2199	diguanylate cyclase activity
YE105_RS12210	COG2814	Major facilitator Superfamily
YE105_RS12215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YE105_RS12220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YE105_RS12225	COG2719	SpoVR family
YE105_RS12230	COG2186	Transcriptional regulator
YE105_RS12235	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YE105_RS12240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YE105_RS12260	COG3142	Participates in the control of copper homeostasis
YE105_RS12265	COG3102	Protein conserved in bacteria
YE105_RS12270	COG0018	arginyl-trna synthetase
YE105_RS12280	COG1702	phosphate starvation-inducible protein PhoH
YE105_RS12295	COG3658	cytochrome
YE105_RS12300	COG1215	transferase activity, transferring glycosyl groups
YE105_RS12305	COG1649	PFAM Uncharacterised BCR, COG1649
YE105_RS12305	COG0726	polysaccharide deacetylase
YE105_RS12310	COG0457	Tetratricopeptide repeat
YE105_RS12315	COG0006	proline dipeptidase activity
YE105_RS12320	COG4114	ferric iron reductase
YE105_RS12325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YE105_RS12350	COG1136	(ABC) transporter
YE105_RS12350	COG0577	efflux transmembrane transporter activity
YE105_RS12360	COG1136	(ABC) transporter
YE105_RS12360	COG0577	efflux transmembrane transporter activity
YE105_RS12375	COG0672	)-iron permease
YE105_RS12390	COG2066	Belongs to the glutaminase family
YE105_RS12395	COG3622	Belongs to the hyi family
YE105_RS12400	COG0235	Class ii aldolase
YE105_RS12405	COG3395	kinase activity
YE105_RS12410	COG1349	DNA-binding transcription factor activity
YE105_RS12415	COG3290	protein histidine kinase activity
YE105_RS12420	COG4565	transcriptional regulatory protein
YE105_RS12425	COG3493	citrate carrier protein
YE105_RS12445	COG2223	nitrite transmembrane transporter activity
YE105_RS12450	COG0561	phosphatase activity
YE105_RS12460	COG3328	transposase activity
YE105_RS12470	COG0500	methyltransferase
YE105_RS12475	COG3328	transposase activity
YE105_RS12520	COG4974	Belongs to the 'phage' integrase family
YE105_RS12530	COG1276	copper resistance
YE105_RS12535	COG2372	response to copper ion
YE105_RS12540	COG1528	Iron-storage protein
YE105_RS12555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YE105_RS12560	COG1770	oligopeptidase
YE105_RS12570	COG3097	Belongs to the UPF0267 family
YE105_RS12575	COG3141	response to X-ray
YE105_RS12580	COG0513	Belongs to the DEAD box helicase family
YE105_RS12585	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YE105_RS12590	COG3140	Belongs to the UPF0181 family
YE105_RS12600	COG0494	nUDIX hydrolase
YE105_RS12605	COG1760	l-serine dehydratase
YE105_RS12610	COG1253	flavin adenine dinucleotide binding
YE105_RS12615	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS12615	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS12620	COG3715	PTS system
YE105_RS12625	COG3716	PTS system mannose fructose sorbose family IID component
YE105_RS12630	COG4811	Protein of unknown function (DUF986)
YE105_RS12635	COG1971	Probably functions as a manganese efflux pump
YE105_RS12645	COG5001	Diguanylate cyclase
YE105_RS12645	COG5002	protein histidine kinase activity
YE105_RS12645	COG3447	MASE1 domain protein
YE105_RS12655	COG2226	methyltransferase
YE105_RS12660	COG0768	penicillin binding
YE105_RS12665	COG1496	oxidoreductase activity
YE105_RS12685	COG1113	amino acid transport
YE105_RS12720	COG2207	Transcriptional regulator
YE105_RS12740	COG1132	(ABC) transporter
YE105_RS12760	COG5001	Diguanylate cyclase
YE105_RS12760	COG4251	negative regulation of phosphorylation
YE105_RS12760	COG2203	Gaf domain
YE105_RS12760	COG3706	GGDEF domain
YE105_RS12775	COG3755	Protein conserved in bacteria
YE105_RS12800	COG1733	regulation of RNA biosynthetic process
YE105_RS12805	COG0702	epimerase
YE105_RS12810	COG2873	o-acetylhomoserine
YE105_RS12830	COG0840	transmembrane signaling receptor activity
YE105_RS12865	COG0538	isocitrate dehydrogenase activity
YE105_RS12900	COG0538	isocitrate dehydrogenase activity
YE105_RS12905	COG1187	pseudouridine synthase activity
YE105_RS12915	COG0482	sulfurtransferase activity
YE105_RS12920	COG2915	High frequency lysogenization protein hflD homolog
YE105_RS12925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YE105_RS12935	COG0745	RESPONSE REGULATOR receiver
YE105_RS12945	COG2850	peptidyl-arginine hydroxylation
YE105_RS12960	COG1940	carbohydrate kinase activity
YE105_RS12965	COG4591	ABC-type transport system involved in lipoprotein release permease component
YE105_RS12975	COG4591	ABC-type transport system involved in lipoprotein release permease component
YE105_RS12980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YE105_RS12985	COG3134	Outer membrane lipoprotein
YE105_RS12990	COG1252	NADH dehydrogenase
YE105_RS12995	COG3150	esterase
YE105_RS13000	COG1472	Belongs to the glycosyl hydrolase 3 family
YE105_RS13010	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
YE105_RS13015	COG5633	Lipoprotein
YE105_RS13020	COG0537	adenosine 5'-monophosphoramidase activity
YE105_RS13025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YE105_RS13035	COG0641	radical SAM
YE105_RS13055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS13055	COG1263	PTS System
YE105_RS13060	COG0084	hydrolase, TatD family'
YE105_RS13065	COG0470	DNA polymerase III
YE105_RS13070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YE105_RS13075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YE105_RS13080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YE105_RS13085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YE105_RS13095	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS13100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YE105_RS13105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YE105_RS13110	COG0416	fatty acid biosynthetic process
YE105_RS13115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YE105_RS13120	COG1399	metal-binding, possibly nucleic acid-binding protein
YE105_RS13125	COG0424	maF-like protein
YE105_RS13130	COG0564	pseudouridine synthase activity
YE105_RS13135	COG1530	ribonuclease E activity
YE105_RS13140	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YE105_RS13145	COG0418	dihydroorotase activity
YE105_RS13170	COG0628	permease
YE105_RS13175	COG1054	Belongs to the UPF0176 family
YE105_RS13210	COG1560	Kdo2-lipid A biosynthetic process
YE105_RS13220	COG2259	Doxx family
YE105_RS13250	COG5645	(Lipo)protein
YE105_RS13255	COG2943	transferase activity, transferring hexosyl groups
YE105_RS13260	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YE105_RS13285	COG3263	regulation of cellular component size
YE105_RS13295	COG3916	Acyl-homoserine-lactone synthase
YE105_RS13300	COG2771	luxR family
YE105_RS13305	COG4235	cytochrome complex assembly
YE105_RS13310	COG3088	subunit of a heme lyase
YE105_RS13315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YE105_RS13320	COG1138	Cytochrome C-type biogenesis protein
YE105_RS13325	COG3301	Polysulphide reductase, NrfD
YE105_RS13330	COG0437	4 iron, 4 sulfur cluster binding
YE105_RS13335	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
YE105_RS13350	COG2920	part of a sulfur-relay system
YE105_RS13355	COG1254	Belongs to the acylphosphatase family
YE105_RS13370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YE105_RS13375	COG3785	DNA binding
YE105_RS13380	COG1832	CoA-binding protein
YE105_RS13390	COG1803	Methylglyoxal synthase
YE105_RS13395	COG0210	DNA helicase
YE105_RS13400	COG3304	Inner membrane component domain
YE105_RS13410	COG3070	regulator of competence-specific genes
YE105_RS13415	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
YE105_RS13425	COG3120	sequence-specific DNA binding
YE105_RS13430	COG1067	ATP-dependent peptidase activity
YE105_RS13435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YE105_RS13450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YE105_RS13455	COG3009	Protein conserved in bacteria
YE105_RS13460	COG3008	intermembrane lipid transfer
YE105_RS13460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YE105_RS13465	COG2995	paraquat-inducible protein a
YE105_RS13470	COG0488	(ABC) transporter
YE105_RS13475	COG0116	Belongs to the methyltransferase superfamily
YE105_RS13475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YE105_RS13480	COG0633	Ferredoxin
YE105_RS13480	COG3217	Mosc domain protein beta barrel domain protein
YE105_RS13490	COG0167	dihydroorotate dehydrogenase activity
YE105_RS13495	COG0308	aminopeptidase N
YE105_RS13500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YE105_RS13505	COG0017	Asparaginyl-tRNA synthetase
YE105_RS13515	COG1448	Aminotransferase
YE105_RS13525	COG2200	EAL domain
YE105_RS13530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YE105_RS13535	COG3108	Peptidase M15
YE105_RS13540	COG2989	Protein conserved in bacteria
YE105_RS13545	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
YE105_RS13555	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YE105_RS13560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YE105_RS13565	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YE105_RS13570	COG3173	Aminoglycoside phosphotransferase
YE105_RS13575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YE105_RS13580	COG2835	tetraacyldisaccharide 4'-kinase activity
YE105_RS13585	COG1278	Cold shock
YE105_RS13595	COG5383	Protein conserved in bacteria
YE105_RS13600	COG1663	tetraacyldisaccharide 4'-kinase activity
YE105_RS13610	COG0658	competence protein
YE105_RS13610	COG2333	competence protein COMEC
YE105_RS13615	COG0776	regulation of translation
YE105_RS13620	COG0539	negative regulation of cytoplasmic translation
YE105_RS13625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YE105_RS13630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YE105_RS13635	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YE105_RS13640	COG2323	membrane
YE105_RS13645	COG0252	asparaginase activity
YE105_RS13650	COG1944	ATP diphosphatase activity
YE105_RS13655	COG2116	formate transmembrane transporter activity
YE105_RS13660	COG1882	Formate acetyltransferase
YE105_RS13665	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YE105_RS13670	COG2814	Major facilitator Superfamily
YE105_RS13680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YE105_RS13685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YE105_RS13690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YE105_RS13695	COG3107	peptidoglycan biosynthetic process
YE105_RS13695	COG1674	ftsk spoiiie
YE105_RS13700	COG1522	sequence-specific DNA binding
YE105_RS13705	COG0492	ferredoxin-NADP+ reductase activity
YE105_RS13715	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YE105_RS13720	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YE105_RS13725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YE105_RS13730	COG0542	response to heat
YE105_RS13735	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YE105_RS13740	COG1278	Cold shock
YE105_RS13750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS13755	COG2990	Protein conserved in bacteria
YE105_RS13760	COG3593	DNA synthesis involved in DNA repair
YE105_RS13765	COG2431	L-lysine efflux transmembrane transporter activity
YE105_RS13770	COG1151	hydroxylamine reductase activity
YE105_RS13775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YE105_RS13780	COG0028	Belongs to the TPP enzyme family
YE105_RS13790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YE105_RS13795	COG0702	epimerase
YE105_RS13800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_RS13810	COG1126	abc transporter atp-binding protein
YE105_RS13815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS13820	COG4215	(ABC) transporter
YE105_RS13825	COG4160	amino acid transport
YE105_RS13830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS13835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YE105_RS13845	COG1177	transmembrane transport
YE105_RS13850	COG1176	ABC-type spermidine putrescine transport system, permease component I
YE105_RS13855	COG3842	ATPase activity
YE105_RS13860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YE105_RS13880	COG2985	domain, Protein
YE105_RS13880	COG0569	domain protein
YE105_RS13890	COG0671	phosphoesterase, PA-phosphatase related
YE105_RS13895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YE105_RS13900	COG1349	DNA-binding transcription factor activity
YE105_RS13905	COG0814	amino acid
YE105_RS13910	COG1760	l-serine dehydratase
YE105_RS13920	COG1686	Belongs to the peptidase S11 family
YE105_RS13930	COG0626	cystathionine gamma-synthase activity
YE105_RS13935	COG2011	ABC-type metal ion transport system permease component
YE105_RS13960	COG0625	glutathione transferase activity
YE105_RS13965	COG4771	TonB-dependent receptor
YE105_RS13975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_RS13980	COG0833	amino acid
YE105_RS13985	COG0583	DNA-binding transcription factor activity
YE105_RS13995	COG2855	membrane
YE105_RS14000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
YE105_RS14025	COG3710	Transcriptional regulator
YE105_RS14030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YE105_RS14030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YE105_RS14030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YE105_RS14035	COG1105	Belongs to the carbohydrate kinase PfkB family
YE105_RS14050	COG3005	denitrification pathway
YE105_RS14055	COG0243	molybdopterin cofactor binding
YE105_RS14070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YE105_RS14075	COG1312	Catalyzes the dehydration of D-mannonate
YE105_RS14085	COG0246	Mannitol dehydrogenase
YE105_RS14090	COG2186	Transcriptional regulator
YE105_RS14100	COG0523	cobalamin synthesis protein
YE105_RS14105	COG0671	phosphoesterase, PA-phosphatase related
YE105_RS14110	COG0791	NLP P60 protein
YE105_RS14120	COG2200	EAL domain
YE105_RS14125	COG4166	transmembrane transport
YE105_RS14130	COG4174	ABC transporter (Permease)
YE105_RS14135	COG4239	(ABC) transporter, permease
YE105_RS14140	COG4172	Belongs to the ABC transporter superfamily
YE105_RS14150	COG2814	Major facilitator Superfamily
YE105_RS14155	COG1187	pseudouridine synthase activity
YE105_RS14160	COG1061	Type III restriction enzyme res subunit
YE105_RS14165	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YE105_RS14170	COG3081	Nucleoid-associated protein
YE105_RS14175	COG3082	Protein of unknown function (DUF1414)
YE105_RS14215	COG2801	Transposase and inactivated derivatives
YE105_RS14235	COG2723	6-phospho-beta-galactosidase activity
YE105_RS14240	COG2190	(PTS) system
YE105_RS14240	COG1263	PTS System
YE105_RS14240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS14245	COG1737	Transcriptional regulator
YE105_RS14300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YE105_RS14315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YE105_RS14335	COG2223	nitrite transmembrane transporter activity
YE105_RS14340	COG0642	Histidine kinase
YE105_RS14340	COG2198	Histidine kinase
YE105_RS14345	COG2197	response regulator
YE105_RS14350	COG0784	Response regulator, receiver
YE105_RS14350	COG2205	protein histidine kinase activity
YE105_RS14360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YE105_RS14365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YE105_RS14375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YE105_RS14380	COG4574	serine-type endopeptidase inhibitor activity
YE105_RS14405	COG0814	amino acid
YE105_RS14425	COG1441	menaquinone biosynthetic process
YE105_RS14430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YE105_RS14435	COG0596	Alpha beta hydrolase
YE105_RS14440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YE105_RS14445	COG1169	isochorismate synthase
YE105_RS14450	COG3328	transposase activity
YE105_RS14455	COG4575	ribosome binding
YE105_RS14460	COG0129	dihydroxy-acid dehydratase activity
YE105_RS14465	COG4702	Belongs to the UPF0303 family
YE105_RS14475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YE105_RS14485	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS14490	COG3265	gluconokinase activity
YE105_RS14510	COG1007	ATP synthesis coupled electron transport
YE105_RS14515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS14520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YE105_RS14525	COG0713	ATP synthesis coupled electron transport
YE105_RS14530	COG0839	Belongs to the complex I subunit 6 family
YE105_RS14535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS14540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YE105_RS14545	COG1034	ATP synthesis coupled electron transport
YE105_RS14560	COG0649	NAD binding
YE105_RS14560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS14565	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS14570	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YE105_RS14575	COG0583	DNA-binding transcription factor activity
YE105_RS14580	COG0436	Aminotransferase
YE105_RS14585	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
YE105_RS14590	COG0471	metal ion transport
YE105_RS14590	COG0490	domain, Protein
YE105_RS14600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_RS14605	COG3013	Belongs to the UPF0304 family
YE105_RS14610	COG3092	negative regulation of chromosome organization
YE105_RS14620	COG0280	phosphate acetyltransferase
YE105_RS14620	COG0857	belongs to the CobB CobQ family
YE105_RS14625	COG1609	Transcriptional regulator
YE105_RS14630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS14640	COG3037	sugar-specific permease SgaT UlaA
YE105_RS14650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YE105_RS14655	COG0622	Phosphoesterase
YE105_RS14665	COG1090	epimerase
YE105_RS14675	COG4598	ABC transporter
YE105_RS14680	COG4160	amino acid transport
YE105_RS14685	COG4215	(ABC) transporter
YE105_RS14690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS14695	COG0163	prenyltransferase activity
YE105_RS14700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YE105_RS14705	COG1286	toxin biosynthetic process
YE105_RS14710	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YE105_RS14715	COG0285	dihydrofolate synthase activity
YE105_RS14720	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YE105_RS14725	COG0586	Pfam SNARE associated Golgi protein
YE105_RS14735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YE105_RS14740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YE105_RS14750	COG0697	spore germination
YE105_RS14755	COG0697	spore germination
YE105_RS14760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_RS14765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YE105_RS14790	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YE105_RS14800	COG1609	Transcriptional regulator
YE105_RS14810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_RS14815	COG2723	6-phospho-beta-galactosidase activity
YE105_RS14820	COG1447	Phosphotransferase system cellobiose-specific component IIA
YE105_RS14830	COG1794	racemase activity, acting on amino acids and derivatives
YE105_RS14835	COG3706	GGDEF domain
YE105_RS14840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YE105_RS14845	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YE105_RS14845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YE105_RS14855	COG3101	peptidyl-lysine hydroxylation
YE105_RS14860	COG0730	response to heat
YE105_RS14865	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
YE105_RS14870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YE105_RS14875	COG2890	protein-(glutamine-N5) methyltransferase activity
YE105_RS14880	COG2840	Smr protein MutS2
YE105_RS14885	COG2062	phosphohistidine phosphatase, SixA
YE105_RS14890	COG1250	3-hydroxyacyl-CoA dehydrogenase
YE105_RS14890	COG1024	Enoyl-CoA hydratase
YE105_RS14895	COG0183	Belongs to the thiolase family
YE105_RS14900	COG3691	Protein conserved in bacteria
YE105_RS14915	COG4235	cytochrome complex assembly
YE105_RS14915	COG3088	subunit of a heme lyase
YE105_RS14925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YE105_RS14930	COG1138	Cytochrome C-type biogenesis protein
YE105_RS14935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
YE105_RS14940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YE105_RS14945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YE105_RS14950	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YE105_RS14970	COG2116	formate transmembrane transporter activity
YE105_RS14980	COG0582	viral genome integration into host DNA
YE105_RS15045	COG2824	Alkylphosphonate utilization operon protein PhnA
YE105_RS15050	COG1695	Transcriptional regulator
YE105_RS15060	COG2723	6-phospho-beta-galactosidase activity
YE105_RS15065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS15065	COG1263	PTS System
YE105_RS15070	COG1609	Transcriptional regulator
YE105_RS15075	COG2353	YceI-like domain
YE105_RS15080	COG3038	cytochrome b561
YE105_RS15085	COG2755	lipolytic protein G-D-S-L family
YE105_RS15085	COG0657	acetylesterase activity
YE105_RS15105	COG1127	ABC transporter
YE105_RS15110	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YE105_RS15140	COG0531	amino acid
YE105_RS15145	COG2951	lytic endotransglycosylase activity
YE105_RS15165	COG1280	lysine exporter protein (LysE YggA)
YE105_RS15175	COG1598	PFAM Uncharacterised protein family UPF0150
YE105_RS15180	COG3038	cytochrome b561
YE105_RS15185	COG0436	Aminotransferase
YE105_RS15200	COG3275	phosphorelay sensor kinase activity
YE105_RS15205	COG3279	Response regulator of the LytR AlgR family
YE105_RS15210	COG2223	nitrite transmembrane transporter activity
YE105_RS15225	COG0837	glucose binding
YE105_RS15240	COG3961	Belongs to the TPP enzyme family
YE105_RS15245	COG0667	Aldo Keto reductase
YE105_RS15255	COG1914	H( )-stimulated, divalent metal cation uptake system
YE105_RS15260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YE105_RS15275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YE105_RS15305	COG3530	Putative quorum-sensing-regulated virulence factor
YE105_RS15310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YE105_RS15330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS15335	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YE105_RS15345	COG2205	protein histidine kinase activity
YE105_RS15350	COG0745	RESPONSE REGULATOR receiver
YE105_RS15355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS15375	COG4208	sulfate ABC transporter
YE105_RS15380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YE105_RS15385	COG4150	thiosulfate binding
YE105_RS15395	COG1737	Transcriptional regulator
YE105_RS15400	COG2731	YhcH YjgK YiaL family protein
YE105_RS15415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YE105_RS15425	COG2837	iron assimilation
YE105_RS15435	COG3111	PFAM Bacterial OB fold (BOF) protein
YE105_RS15440	COG0456	acetyltransferase
YE105_RS15445	COG0408	coproporphyrinogen oxidase activity
YE105_RS15450	COG1671	Belongs to the UPF0178 family
YE105_RS15465	COG0280	phosphate acetyltransferase
YE105_RS15465	COG0281	malic enzyme
YE105_RS15470	COG0494	nUDIX hydrolase
YE105_RS15475	COG3005	denitrification pathway
YE105_RS15480	COG3043	anaerobic respiration
YE105_RS15485	COG0243	molybdopterin cofactor binding
YE105_RS15490	COG3062	negative regulation of establishment of protein localization
YE105_RS15500	COG2197	response regulator
YE105_RS15510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_RS15525	COG1393	Belongs to the ArsC family
YE105_RS15530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YE105_RS15535	COG1876	peptidase activity
YE105_RS15580	COG0400	carboxylic ester hydrolase activity
YE105_RS15590	COG1444	tRNA N-acetyltransferase activity
YE105_RS15595	COG2707	UPF0756 membrane protein
YE105_RS15605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YE105_RS15610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YE105_RS15615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YE105_RS15620	COG2716	regulation of RNA biosynthetic process
YE105_RS15625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YE105_RS15630	COG0628	permease
YE105_RS15635	COG4783	chaperone-mediated protein folding
YE105_RS15640	COG1393	Belongs to the ArsC family
YE105_RS15645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YE105_RS15650	COG2233	PERMEase
YE105_RS15655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YE105_RS15660	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YE105_RS15665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YE105_RS15670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YE105_RS15685	COG0581	inorganic phosphate transmembrane transporter activity
YE105_RS15690	COG0573	inorganic phosphate transmembrane transporter activity
YE105_RS15695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YE105_RS15710	COG2239	Acts as a magnesium transporter
YE105_RS15715	COG5002	protein histidine kinase activity
YE105_RS15715	COG3447	MASE1 domain protein
YE105_RS15715	COG5001	Diguanylate cyclase
YE105_RS15720	COG0443	Heat shock 70 kDa protein
YE105_RS15725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YE105_RS15735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_RS15740	COG0477	Major facilitator Superfamily
YE105_RS15745	COG2205	protein histidine kinase activity
YE105_RS15750	COG0745	RESPONSE REGULATOR receiver
YE105_RS15755	COG3422	double-strand break repair
YE105_RS15760	COG0826	peptidase U32
YE105_RS15765	COG1597	lipid kinase activity
YE105_RS15770	COG3730	PTS system glucitol sorbitol-specific
YE105_RS15785	COG1028	Short-chain dehydrogenase reductase Sdr
YE105_RS15790	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS15795	COG1349	DNA-binding transcription factor activity
YE105_RS15815	COG0351	phosphomethylpyrimidine kinase
YE105_RS15850	COG0519	Catalyzes the synthesis of GMP from XMP
YE105_RS15850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YE105_RS15855	COG0517	IMP dehydrogenase activity
YE105_RS15855	COG0516	GMP reductase activity
YE105_RS15860	COG1570	exodeoxyribonuclease VII activity
YE105_RS15865	COG1645	bacterial-type flagellum-dependent swarming motility
YE105_RS15880	COG1160	GTP binding
YE105_RS15890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YE105_RS15895	COG2976	Protein conserved in bacteria
YE105_RS15900	COG0124	histidyl-tRNA synthetase
YE105_RS15905	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YE105_RS15910	COG1426	Protein conserved in bacteria
YE105_RS15920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YE105_RS15935	COG4953	penicillin-binding protein 1C
YE105_RS15940	COG2373	Large extracellular alpha-helical protein
YE105_RS15945	COG3468	outer membrane autotransporter barrel domain protein
YE105_RS15960	COG2975	iron-sulfur cluster assembly
YE105_RS15965	COG0633	Ferredoxin
YE105_RS15970	COG0443	Heat shock 70 kDa protein
YE105_RS15975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YE105_RS15980	COG0316	Belongs to the HesB IscA family
YE105_RS15985	COG0822	iron-sulfur transferase activity
YE105_RS15995	COG1959	2 iron, 2 sulfur cluster binding
YE105_RS16000	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
YE105_RS16010	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YE105_RS16015	COG3683	transport system, periplasmic component
YE105_RS16020	COG3711	transcriptional antiterminator
YE105_RS16025	COG2814	Major facilitator Superfamily
YE105_RS16030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YE105_RS16035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YE105_RS16035	COG1017	nitric oxide dioxygenase activity
YE105_RS16040	COG2188	Transcriptional regulator
YE105_RS16050	COG3457	Alanine racemase
YE105_RS16055	COG1735	metal-dependent hydrolase with the TIM-barrel fold
YE105_RS16070	COG0347	Belongs to the P(II) protein family
YE105_RS16075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YE105_RS16075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YE105_RS16080	COG2204	response regulator
YE105_RS16085	COG3170	Tfp pilus assembly protein FimV
YE105_RS16090	COG2205	protein histidine kinase activity
YE105_RS16105	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YE105_RS16120	COG0560	Phosphoserine phosphatase
YE105_RS16130	COG1737	Transcriptional regulator
YE105_RS16135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YE105_RS16140	COG2610	gluconate transmembrane transporter activity
YE105_RS16145	COG0736	holo-[acyl-carrier-protein] synthase activity
YE105_RS16150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YE105_RS16155	COG1381	Involved in DNA repair and RecF pathway recombination
YE105_RS16160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YE105_RS16165	COG0571	ribonuclease III activity
YE105_RS16175	COG0481	GTPase activity
YE105_RS16185	COG3086	response to oxidative stress
YE105_RS16195	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YE105_RS16205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YE105_RS16210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
YE105_RS16215	COG0513	Belongs to the DEAD box helicase family
YE105_RS16245	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
YE105_RS16250	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YE105_RS16255	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YE105_RS16260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YE105_RS16265	COG0497	DNA recombination
YE105_RS16270	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YE105_RS16280	COG2867	negative regulation of translational initiation
YE105_RS16285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YE105_RS16290	COG0582	viral genome integration into host DNA
YE105_RS16330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YE105_RS16355	COG3394	polysaccharide catabolic process
YE105_RS16360	COG2169	Transcriptional regulator
YE105_RS16360	COG1917	Cupin 2, conserved barrel domain protein
YE105_RS16365	COG1447	Phosphotransferase system cellobiose-specific component IIA
YE105_RS16370	COG2723	6-phospho-beta-galactosidase activity
YE105_RS16375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_RS16380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_RS16385	COG2133	pyrroloquinoline quinone binding
YE105_RS16410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YE105_RS16420	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YE105_RS16425	COG4413	Urea transporter
YE105_RS16430	COG0829	nickel cation binding
YE105_RS16435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YE105_RS16440	COG0830	nickel cation binding
YE105_RS16445	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
YE105_RS16450	COG0804	urea catabolic process
YE105_RS16455	COG0832	Belongs to the urease beta subunit family
YE105_RS16460	COG0831	urea catabolic process
YE105_RS16465	COG1124	(ABC) transporter
YE105_RS16475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_RS16515	COG1278	Cold shock
YE105_RS16540	COG2207	Transcriptional regulator
YE105_RS16560	COG4575	ribosome binding
YE105_RS16570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YE105_RS16580	COG1780	Probably involved in ribonucleotide reductase function
YE105_RS16590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YE105_RS16600	COG4176	ABC-type proline glycine betaine transport system permease component
YE105_RS16605	COG2113	Glycine betaine
YE105_RS16620	COG0328	RNA-DNA hybrid ribonuclease activity
YE105_RS16625	COG2226	methyltransferase
YE105_RS16630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YE105_RS16635	COG0741	lytic transglycosylase activity
YE105_RS16635	COG1388	LysM domain
YE105_RS16645	COG3021	interspecies interaction between organisms
YE105_RS16650	COG2814	Major facilitator Superfamily
YE105_RS16655	COG0583	DNA-binding transcription factor activity
YE105_RS16660	COG0656	L-ascorbic acid biosynthetic process
YE105_RS16670	COG3328	transposase activity
YE105_RS16720	COG0191	fructose-bisphosphate aldolase activity
YE105_RS16725	COG0126	phosphoglycerate kinase activity
YE105_RS16730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YE105_RS16735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YE105_RS16740	COG0501	Belongs to the peptidase M48B family
YE105_RS16750	COG1166	arginine decarboxylase activity
YE105_RS16755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YE105_RS16770	COG0640	Transcriptional regulator
YE105_RS16775	COG3091	SprT-like family
YE105_RS16780	COG2356	endonuclease I
YE105_RS16785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YE105_RS16790	COG0189	ligase activity
YE105_RS16795	COG1678	Uncharacterized ACR, COG1678
YE105_RS16800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YE105_RS16805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YE105_RS16815	COG2805	Type II/IV secretion system protein
YE105_RS16820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YE105_RS16825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YE105_RS16830	COG0762	integral membrane protein
YE105_RS16835	COG1872	DUF167
YE105_RS16840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YE105_RS16845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YE105_RS16860	COG3171	Protein conserved in bacteria
YE105_RS16865	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YE105_RS16870	COG1194	a g-specific adenine glycosylase
YE105_RS16875	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YE105_RS16880	COG0741	lytic transglycosylase activity
YE105_RS16890	COG1982	Orn Lys Arg decarboxylase major
YE105_RS16905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YE105_RS16945	COG0531	amino acid
YE105_RS16950	COG1982	Orn Lys Arg decarboxylase major
YE105_RS16960	COG1289	transmembrane transporter activity
YE105_RS16985	COG0024	Methionine aminopeptidase
YE105_RS16990	COG4604	ABC transporter, ATP-binding protein
YE105_RS16995	COG4605	iron ion homeostasis
YE105_RS17005	COG4607	ABC-type enterochelin transport system periplasmic component
YE105_RS17030	COG0477	Major facilitator Superfamily
YE105_RS17035	COG1609	Transcriptional regulator
YE105_RS17045	COG1283	sodium-dependent phosphate transmembrane transporter activity
YE105_RS17060	COG0477	Major facilitator Superfamily
YE105_RS17080	COG5001	Diguanylate cyclase
YE105_RS17090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
YE105_RS17100	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
YE105_RS17105	COG0309	Hydrogenase expression formation protein (HypE)
YE105_RS17110	COG0409	Hydrogenase expression formation protein
YE105_RS17115	COG0298	carbon dioxide binding
YE105_RS17120	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YE105_RS17130	COG1773	rubredoxin
YE105_RS17135	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YE105_RS17140	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
YE105_RS17145	COG5557	Pfam Polysulphide reductase, NrfD
YE105_RS17150	COG0437	4 iron, 4 sulfur cluster binding
YE105_RS17155	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
YE105_RS17160	COG3133	Outer membrane lipoprotein
YE105_RS17170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YE105_RS17175	COG1191	sigma factor activity
YE105_RS17195	COG1516	flagellar protein fliS
YE105_RS17200	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YE105_RS17205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YE105_RS17210	COG3710	Transcriptional regulator
YE105_RS17240	COG1706	bacterial-type flagellum-dependent cell motility
YE105_RS17250	COG4786	Flagellar basal body rod
YE105_RS17265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YE105_RS17270	COG1558	bacterial-type flagellum-dependent cell motility
YE105_RS17275	COG1815	bacterial-type flagellum-dependent cell motility
YE105_RS17325	COG1677	Flagellar hook-basal body complex protein FliE
YE105_RS17350	COG1987	bacterial-type flagellum assembly
YE105_RS17360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YE105_RS17375	COG0840	transmembrane signaling receptor activity
YE105_RS17380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YE105_RS17385	COG2271	Major facilitator Superfamily
YE105_RS17390	COG4592	Periplasmic binding protein
YE105_RS17395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_RS17400	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YE105_RS17405	COG1120	ATPase activity
YE105_RS17420	COG2801	Transposase and inactivated derivatives
YE105_RS17435	COG0577	efflux transmembrane transporter activity
YE105_RS17435	COG1136	(ABC) transporter
YE105_RS17470	COG2135	peptidase activity
YE105_RS17475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YE105_RS17505	COG4964	Belongs to the GSP D family
YE105_RS17555	COG0848	biopolymer transport protein
YE105_RS17565	COG0626	cystathionine gamma-synthase activity
YE105_RS17570	COG0586	Pfam SNARE associated Golgi protein
YE105_RS17575	COG2207	Transcriptional regulator
YE105_RS17580	COG1979	alcohol dehydrogenase
YE105_RS17585	COG0656	L-ascorbic acid biosynthetic process
YE105_RS17595	COG2132	Multicopper oxidase
YE105_RS17605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YE105_RS17610	COG2249	NAD(P)H dehydrogenase (quinone) activity
YE105_RS17615	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YE105_RS17630	COG3150	esterase
YE105_RS17635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YE105_RS17640	COG3151	Protein conserved in bacteria
YE105_RS17645	COG0494	nUDIX hydrolase
YE105_RS17650	COG1538	Outer membrane efflux protein
YE105_RS17655	COG5463	Belongs to the UPF0441 family
YE105_RS17660	COG0754	glutathionylspermidine amidase activity
YE105_RS17665	COG3384	dioxygenase
YE105_RS17670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YE105_RS17680	COG0531	amino acid
YE105_RS17685	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YE105_RS17685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YE105_RS17690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YE105_RS17695	COG3025	triphosphatase activity
YE105_RS17700	COG4991	sh3 domain protein
YE105_RS17705	COG0617	tRNA 3'-terminal CCA addition
YE105_RS17710	COG1968	undecaprenyl-diphosphatase activity
YE105_RS17715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YE105_RS17725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YE105_RS17730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YE105_RS17735	COG0358	DNA primase activity
YE105_RS17755	COG3876	Protein conserved in bacteria
YE105_RS17765	COG1472	Belongs to the glycosyl hydrolase 3 family
YE105_RS17775	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
YE105_RS17780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS17780	COG1263	PTS System
YE105_RS17790	COG0531	amino acid
YE105_RS17795	COG0076	glutamate decarboxylase activity
YE105_RS17805	COG3247	response to pH
YE105_RS17815	COG0446	pyridine nucleotide-disulphide oxidoreductase
YE105_RS17815	COG1902	pentaerythritol trinitrate reductase activity
YE105_RS17825	COG2813	Specifically methylates the guanine in position
YE105_RS17845	COG1451	nucleotide metabolic process
YE105_RS17850	COG0673	inositol 2-dehydrogenase activity
YE105_RS17860	COG0861	Integral membrane protein TerC family
YE105_RS17865	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
YE105_RS17875	COG2721	sulfolactate sulfo-lyase activity
YE105_RS17880	COG0246	Mannitol dehydrogenase
YE105_RS17885	COG1904	glucuronate isomerase
YE105_RS17890	COG2271	Major facilitator Superfamily
YE105_RS17905	COG0586	Pfam SNARE associated Golgi protein
YE105_RS17920	COG4575	ribosome binding
YE105_RS17925	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YE105_RS17935	COG2259	Doxx family
YE105_RS17940	COG0435	Glutathione S-transferase
YE105_RS17945	COG0583	DNA-binding transcription factor activity
YE105_RS17950	COG1741	Belongs to the pirin family
YE105_RS17955	COG1064	alcohol dehydrogenase
YE105_RS17960	COG0667	Aldo Keto reductase
YE105_RS17980	COG3121	Chaperone
YE105_RS17995	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YE105_RS18005	COG0792	nuclease activity
YE105_RS18010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YE105_RS18015	COG2823	Periplasmic or secreted lipoprotein
YE105_RS18020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YE105_RS18025	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YE105_RS18030	COG2198	Histidine kinase
YE105_RS18030	COG0784	Response regulator, receiver
YE105_RS18030	COG5002	protein histidine kinase activity
YE105_RS18035	COG1242	4 iron, 4 sulfur cluster binding
YE105_RS18040	COG0067	glutamate synthase
YE105_RS18040	COG0069	glutamate synthase activity
YE105_RS18040	COG0070	glutamate synthase
YE105_RS18045	COG0493	'glutamate synthase
YE105_RS18060	COG2969	positive regulation of protein catabolic process
YE105_RS18065	COG0625	glutathione transferase activity
YE105_RS18070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YE105_RS18075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YE105_RS18080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YE105_RS18085	COG3105	Protein conserved in bacteria
YE105_RS18090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YE105_RS18095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YE105_RS18100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YE105_RS18105	COG5007	Belongs to the BolA IbaG family
YE105_RS18110	COG3113	response to antibiotic
YE105_RS18115	COG2854	intermembrane phospholipid transfer
YE105_RS18120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YE105_RS18125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YE105_RS18130	COG1127	ABC transporter
YE105_RS18135	COG0530	calcium, potassium:sodium antiporter activity
YE105_RS18140	COG0517	IMP dehydrogenase activity
YE105_RS18140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YE105_RS18145	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YE105_RS18150	COG3117	lipopolysaccharide transmembrane transporter activity
YE105_RS18155	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YE105_RS18160	COG1137	ATPase activity
YE105_RS18165	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YE105_RS18180	COG1660	Displays ATPase and GTPase activities
YE105_RS18185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS18190	COG0540	Belongs to the ATCase OTCase family
YE105_RS18195	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
YE105_RS18205	COG2308	Evidence 4 Homologs of previously reported genes of
YE105_RS18225	COG0366	Alpha amylase catalytic
YE105_RS18230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YE105_RS18230	COG1263	PTS System
YE105_RS18240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YE105_RS18250	COG3093	addiction module antidote protein HigA
YE105_RS18255	COG3711	transcriptional antiterminator
YE105_RS18255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS18260	COG2706	6-phosphogluconolactonase activity
YE105_RS18275	COG3964	amidohydrolase
YE105_RS18305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YE105_RS18310	COG3783	Cytochrome b(562)
YE105_RS18320	COG0312	modulator of DNA gyrase
YE105_RS18325	COG3028	Belongs to the UPF0307 family
YE105_RS18330	COG2732	(Barnase) inhibitor
YE105_RS18345	COG1289	transmembrane transporter activity
YE105_RS18350	COG1566	PFAM secretion protein HlyD family protein
YE105_RS18360	COG0583	DNA-binding transcription factor activity
YE105_RS18415	COG0312	modulator of DNA gyrase
YE105_RS18420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YE105_RS18425	COG3164	Protein of unknown function
YE105_RS18435	COG0424	maF-like protein
YE105_RS18440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YE105_RS18445	COG1792	Involved in formation and maintenance of cell shape
YE105_RS18450	COG1077	Cell shape determining protein MreB Mrl
YE105_RS18455	COG2199	diguanylate cyclase activity
YE105_RS18455	COG2200	EAL domain
YE105_RS18460	COG0604	alcohol dehydrogenase
YE105_RS18470	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YE105_RS18475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YE105_RS18480	COG0511	ligase activity, forming carbon-carbon bonds
YE105_RS18485	COG0439	Biotin carboxylase
YE105_RS18490	COG3924	membrane
YE105_RS18495	COG4145	pantothenate transmembrane transporter activity
YE105_RS18500	COG2264	protein methyltransferase activity
YE105_RS18505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YE105_RS18510	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YE105_RS18520	COG3133	Outer membrane lipoprotein
YE105_RS18525	COG1278	Cold shock
YE105_RS18530	COG1278	Cold shock
YE105_RS18535	COG0471	metal ion transport
YE105_RS18540	COG1560	Kdo2-lipid A biosynthetic process
YE105_RS18550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS18555	COG4597	amino acid ABC transporter
YE105_RS18560	COG0765	amino acid transport
YE105_RS18565	COG1126	abc transporter atp-binding protein
YE105_RS18575	COG1380	Effector of murein hydrolase LrgA
YE105_RS18580	COG0583	DNA-binding transcription factor activity
YE105_RS18585	COG0025	NhaP-type Na H and K H
YE105_RS18590	COG2252	PERMEase
YE105_RS18605	COG3550	peptidyl-serine autophosphorylation
YE105_RS18615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YE105_RS18620	COG2315	Protein conserved in bacteria
YE105_RS18630	COG1448	Aminotransferase
YE105_RS18660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YE105_RS18670	COG0735	belongs to the Fur family
YE105_RS18675	COG3237	CsbD-like
YE105_RS18680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YE105_RS18685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YE105_RS18690	COG2937	Belongs to the GPAT DAPAT family
YE105_RS18695	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YE105_RS18700	COG3161	chorismate lyase activity
YE105_RS18715	COG4580	involved in the transport of maltose and maltodextrins
YE105_RS18725	COG2182	Extracellular solute-binding protein
YE105_RS18730	COG1175	transmembrane transport
YE105_RS18735	COG3833	ABC-type maltose transport systems, permease component
YE105_RS18750	COG0166	Belongs to the GPI family
YE105_RS18755	COG0527	aspartate kinase activity
YE105_RS18780	COG1414	Transcriptional regulator
YE105_RS18785	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YE105_RS18790	COG2224	Isocitrate lyase
YE105_RS18795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YE105_RS18800	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
YE105_RS18840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YE105_RS18845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YE105_RS18850	COG0009	L-threonylcarbamoyladenylate synthase
YE105_RS18855	COG0551	DNA topoisomerase type I activity
YE105_RS18865	COG0758	DNA mediated transformation
YE105_RS18870	COG0242	peptide deformylase activity
YE105_RS18875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YE105_RS18880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YE105_RS18880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YE105_RS18890	COG1970	mechanosensitive ion channel activity
YE105_RS18900	COG3036	rescue of stalled ribosome
YE105_RS18905	COG0789	Transcriptional regulator
YE105_RS18915	COG0203	ribosomal protein L17
YE105_RS18920	COG0202	RNA polymerase activity
YE105_RS18925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YE105_RS18930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YE105_RS18935	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YE105_RS18940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YE105_RS18945	COG0201	protein transport
YE105_RS18950	COG0200	Binds to the 23S rRNA
YE105_RS18955	COG1841	ribosomal large subunit assembly
YE105_RS18960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YE105_RS18965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YE105_RS18970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YE105_RS18980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YE105_RS18985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YE105_RS18990	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YE105_RS18995	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YE105_RS19000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YE105_RS19005	COG0255	Belongs to the universal ribosomal protein uL29 family
YE105_RS19010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YE105_RS19015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YE105_RS19020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YE105_RS19025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YE105_RS19030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YE105_RS19035	COG0089	rRNA binding
YE105_RS19040	COG0088	Forms part of the polypeptide exit tunnel
YE105_RS19045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YE105_RS19050	COG0051	transcription antitermination factor activity, RNA binding
YE105_RS19065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YE105_RS19075	COG0049	tRNA binding
YE105_RS19080	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YE105_RS19085	COG2168	tRNA wobble position uridine thiolation
YE105_RS19090	COG2923	Belongs to the DsrF TusC family
YE105_RS19095	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YE105_RS19100	COG2964	Protein conserved in bacteria
YE105_RS19105	COG0545	Peptidyl-prolyl cis-trans isomerase
YE105_RS19110	COG2900	Belongs to the SlyX family
YE105_RS19115	COG1047	Peptidyl-prolyl cis-trans
YE105_RS19120	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YE105_RS19130	COG2249	NAD(P)H dehydrogenase (quinone) activity
YE105_RS19135	COG0488	(ABC) transporter
YE105_RS19140	COG1216	Glycosyl transferase, family 2
YE105_RS19150	COG2175	clavaminate synthase activity
YE105_RS19155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YE105_RS19165	COG4521	taurine ABC transporter
YE105_RS19180	COG0429	hydrolase of the alpha beta-hydrolase fold
YE105_RS19185	COG3089	Belongs to the UPF0270 family
YE105_RS19190	COG3954	Phosphoribulokinase
YE105_RS19195	COG1765	OsmC-like protein
YE105_RS19205	COG1289	transmembrane transporter activity
YE105_RS19220	COG0433	COG0433 Predicted ATPase
YE105_RS19225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YE105_RS19230	COG1486	melibiose metabolic process
YE105_RS19240	COG0738	Major facilitator superfamily
YE105_RS19245	COG0402	S-adenosylhomocysteine deaminase activity
YE105_RS19250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YE105_RS19265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YE105_RS19265	COG1648	precorrin-2 dehydrogenase activity
YE105_RS19270	COG0180	Tryptophanyl-tRNA synthetase
YE105_RS19280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YE105_RS19300	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YE105_RS19305	COG4796	Type ii and iii secretion system protein
YE105_RS19330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YE105_RS19335	COG0494	nUDIX hydrolase
YE105_RS19345	COG1011	Hydrolase
YE105_RS19350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YE105_RS19360	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YE105_RS19375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YE105_RS19400	COG2183	response to ionizing radiation
YE105_RS19405	COG1918	ferrous iron import across plasma membrane
YE105_RS19410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
YE105_RS19425	COG0596	Alpha beta hydrolase
YE105_RS19435	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
YE105_RS19435	COG0316	Belongs to the HesB IscA family
YE105_RS19450	COG1640	4-alpha-glucanotransferase
YE105_RS19455	COG0058	SHG alpha-glucan phosphorylase activity
YE105_RS19460	COG2909	trisaccharide binding
YE105_RS19475	COG0705	Rhomboid family
YE105_RS19480	COG1349	DNA-binding transcription factor activity
YE105_RS19490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YE105_RS19495	COG0058	SHG alpha-glucan phosphorylase activity
YE105_RS19500	COG0297	glycogen (starch) synthase activity
YE105_RS19510	COG1523	belongs to the glycosyl hydrolase 13 family
YE105_RS19515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YE105_RS19520	COG3275	phosphorelay sensor kinase activity
YE105_RS19540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YE105_RS19545	COG2095	MarC family integral membrane protein
YE105_RS19550	COG3265	gluconokinase activity
YE105_RS19555	COG2610	gluconate transmembrane transporter activity
YE105_RS19560	COG1609	Transcriptional regulator
YE105_RS19565	COG1741	Belongs to the pirin family
YE105_RS19570	COG1247	-acetyltransferase
YE105_RS19575	COG1082	Xylose isomerase domain protein TIM barrel
YE105_RS19580	COG0673	inositol 2-dehydrogenase activity
YE105_RS19590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_RS19600	COG3718	enzyme involved in inositol metabolism
YE105_RS19610	COG2814	Major facilitator Superfamily
YE105_RS19615	COG0583	DNA-binding transcription factor activity
YE105_RS19625	COG0561	phosphatase activity
YE105_RS19635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_RS19635	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YE105_RS19640	COG0583	DNA-binding transcription factor activity
YE105_RS19645	COG1648	precorrin-2 dehydrogenase activity
YE105_RS19645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YE105_RS19655	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YE105_RS19665	COG4865	methylaspartate mutase activity
YE105_RS19670	COG3799	methylaspartate ammonia-lyase activity
YE105_RS19685	COG1301	dicarboxylic acid transport
YE105_RS19690	COG2081	HI0933 family
YE105_RS19695	COG0306	phosphate transporter
YE105_RS19705	COG0589	response to stress
YE105_RS19720	COG0742	ribosomal rna small subunit methyltransferase
YE105_RS19730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YE105_RS19735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YE105_RS19745	COG1295	ribonuclease BN
YE105_RS19750	COG2134	cdp-diacylglycerol pyrophosphatase
YE105_RS19755	COG2982	Protein involved in outer membrane biogenesis
YE105_RS19760	COG2200	EAL domain
YE105_RS19765	COG1942	4-Oxalocrotonate Tautomerase
YE105_RS19770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YE105_RS19775	COG0612	Peptidase, M16
YE105_RS19780	COG1301	dicarboxylic acid transport
YE105_RS19795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YE105_RS19800	COG2199	diguanylate cyclase activity
YE105_RS19800	COG2200	EAL domain
YE105_RS19810	COG0457	Tetratricopeptide repeat
YE105_RS19810	COG3118	belongs to the thioredoxin family
YE105_RS19815	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YE105_RS19820	COG1215	transferase activity, transferring glycosyl groups
YE105_RS19825	COG1215	transferase activity, transferring glycosyl groups
YE105_RS19830	COG1192	Involved in chromosome partitioning
YE105_RS19850	COG2194	sulfuric ester hydrolase activity
YE105_RS19855	COG4608	Belongs to the ABC transporter superfamily
YE105_RS19860	COG0444	Belongs to the ABC transporter superfamily
YE105_RS19865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YE105_RS19870	COG0601	transmembrane transport
YE105_RS19875	COG0747	negative chemotaxis
YE105_RS19885	COG1764	response to oxidative stress
YE105_RS19890	COG2194	sulfuric ester hydrolase activity
YE105_RS19895	COG2197	response regulator
YE105_RS19900	COG3851	Histidine kinase
YE105_RS19905	COG2271	Major facilitator Superfamily
YE105_RS19920	COG2831	hemolysin activation secretion protein
YE105_RS19925	COG3210	domain, Protein
YE105_RS19935	COG3328	transposase activity
YE105_RS19960	COG1609	Transcriptional regulator
YE105_RS19965	COG1940	carbohydrate kinase activity
YE105_RS19970	COG1447	Phosphotransferase system cellobiose-specific component IIA
YE105_RS19975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_RS19980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_RS19985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YE105_RS20000	COG2723	6-phospho-beta-galactosidase activity
YE105_RS20005	COG1482	cell wall glycoprotein biosynthetic process
YE105_RS20020	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YE105_RS20025	COG2986	histidine ammonia-lyase
YE105_RS20060	COG0582	viral genome integration into host DNA
YE105_RS20065	COG2207	Transcriptional regulator
YE105_RS20065	COG1609	Transcriptional regulator
YE105_RS20070	COG4214	carbohydrate transport
YE105_RS20080	COG4213	ABC transporter substrate-binding protein
YE105_RS20085	COG2115	Belongs to the xylose isomerase family
YE105_RS20090	COG1070	Carbohydrate kinase
YE105_RS20095	COG3121	Chaperone
YE105_RS20110	COG3274	enterobacterial common antigen metabolic process
YE105_RS20120	COG3276	selenocysteine insertion sequence binding
YE105_RS20125	COG1921	L-seryl-tRNASec selenium transferase activity
YE105_RS20130	COG3058	Necessary for formate dehydrogenase activity
YE105_RS20135	COG2864	formate dehydrogenase
YE105_RS20140	COG0437	4 iron, 4 sulfur cluster binding
YE105_RS20145	COG3383	formate dehydrogenase (NAD+) activity
YE105_RS20145	COG0243	molybdopterin cofactor binding
YE105_RS20150	COG0243	molybdopterin cofactor binding
YE105_RS20150	COG3383	formate dehydrogenase (NAD+) activity
YE105_RS20155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YE105_RS20160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YE105_RS20165	COG0840	transmembrane signaling receptor activity
YE105_RS20170	COG2258	MOSC domain
YE105_RS20190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YE105_RS20200	COG3722	fumarate hydratase activity
YE105_RS20205	COG0246	Mannitol dehydrogenase
YE105_RS20210	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YE105_RS20210	COG2213	PTS system mannitol-specific
YE105_RS20220	COG0751	glycine-tRNA ligase activity
YE105_RS20225	COG0752	glycyl-tRNA synthetase alpha subunit
YE105_RS20230	COG2818	Glycosylase
YE105_RS20235	COG0456	acetyltransferase
YE105_RS20265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YE105_RS20270	COG0366	Alpha amylase catalytic
YE105_RS20275	COG3977	Valine--pyruvate aminotransferase
YE105_RS20280	COG0569	domain protein
YE105_RS20280	COG2985	domain, Protein
YE105_RS20305	COG5645	(Lipo)protein
YE105_RS20310	COG0823	Involved in the tonB-independent uptake of proteins
YE105_RS20320	COG2423	ornithine cyclodeaminase activity
YE105_RS20325	COG0561	phosphatase activity
YE105_RS20330	COG0187	DNA topoisomerase II activity
YE105_RS20335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YE105_RS20340	COG0592	DNA-directed DNA polymerase activity
YE105_RS20345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YE105_RS20350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YE105_RS20355	COG0594	ribonuclease P activity
YE105_RS20365	COG0706	membrane insertase activity
YE105_RS20370	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YE105_RS20375	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YE105_RS20385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YE105_RS20390	COG2011	ABC-type metal ion transport system permease component
YE105_RS20395	COG0840	transmembrane signaling receptor activity
YE105_RS20400	COG0431	NADPH-dependent FMN reductase
YE105_RS20420	COG2252	PERMEase
YE105_RS20425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YE105_RS20430	COG0765	amino acid transport
YE105_RS20435	COG0765	amino acid transport
YE105_RS20440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YE105_RS20450	COG0704	Plays a role in the regulation of phosphate uptake
YE105_RS20460	COG0581	inorganic phosphate transmembrane transporter activity
YE105_RS20465	COG0573	inorganic phosphate transmembrane transporter activity
YE105_RS20470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YE105_RS20485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YE105_RS20490	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YE105_RS20495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YE105_RS20500	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YE105_RS20505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YE105_RS20510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YE105_RS20515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YE105_RS20525	COG0356	it plays a direct role in the translocation of protons across the membrane
YE105_RS20530	COG3312	ion transport
YE105_RS20535	COG0357	Ribosomal RNA small subunit methyltransferase G
YE105_RS20540	COG0445	tRNA wobble uridine modification
YE105_RS20590	COG0714	Associated with various cellular activities
YE105_RS20660	COG0477	Major facilitator Superfamily
YE105_RS20740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS20740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS20755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS20755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YE105_RS20910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YE105_RS20955	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA