locus-tag	class	description
YEY1_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YEY1_RS00010	COG0592	DNA-directed DNA polymerase activity
YEY1_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YEY1_RS00020	COG0187	DNA topoisomerase II activity
YEY1_RS00025	COG0561	phosphatase activity
YEY1_RS00030	COG2423	ornithine cyclodeaminase activity
YEY1_RS00040	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_RS00045	COG5645	(Lipo)protein
YEY1_RS00065	COG2985	domain, Protein
YEY1_RS00065	COG0569	domain protein
YEY1_RS00070	COG3977	Valine--pyruvate aminotransferase
YEY1_RS00075	COG0366	Alpha amylase catalytic
YEY1_RS00080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YEY1_RS00110	COG0456	acetyltransferase
YEY1_RS00115	COG2818	Glycosylase
YEY1_RS00120	COG0752	glycyl-tRNA synthetase alpha subunit
YEY1_RS00125	COG0751	glycine-tRNA ligase activity
YEY1_RS00140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS00140	COG2213	PTS system mannitol-specific
YEY1_RS00145	COG0246	Mannitol dehydrogenase
YEY1_RS00150	COG3722	fumarate hydratase activity
YEY1_RS00160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_RS00180	COG2258	MOSC domain
YEY1_RS00185	COG0840	transmembrane signaling receptor activity
YEY1_RS00190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YEY1_RS00195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YEY1_RS00200	COG3383	formate dehydrogenase (NAD+) activity
YEY1_RS00200	COG0243	molybdopterin cofactor binding
YEY1_RS00205	COG3383	formate dehydrogenase (NAD+) activity
YEY1_RS00205	COG0243	molybdopterin cofactor binding
YEY1_RS00210	COG0437	4 iron, 4 sulfur cluster binding
YEY1_RS00215	COG2864	formate dehydrogenase
YEY1_RS00220	COG3058	Necessary for formate dehydrogenase activity
YEY1_RS00225	COG1921	L-seryl-tRNASec selenium transferase activity
YEY1_RS00230	COG3276	selenocysteine insertion sequence binding
YEY1_RS00240	COG3274	enterobacterial common antigen metabolic process
YEY1_RS00255	COG3121	Chaperone
YEY1_RS00260	COG1070	Carbohydrate kinase
YEY1_RS00265	COG2115	Belongs to the xylose isomerase family
YEY1_RS00270	COG4213	ABC transporter substrate-binding protein
YEY1_RS00280	COG4214	carbohydrate transport
YEY1_RS00290	COG0582	viral genome integration into host DNA
YEY1_RS00340	COG2986	histidine ammonia-lyase
YEY1_RS00345	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YEY1_RS00370	COG1482	cell wall glycoprotein biosynthetic process
YEY1_RS00375	COG2723	6-phospho-beta-galactosidase activity
YEY1_RS00390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_RS00395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_RS00400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_RS00405	COG1447	Phosphotransferase system cellobiose-specific component IIA
YEY1_RS00410	COG1940	carbohydrate kinase activity
YEY1_RS00415	COG1609	Transcriptional regulator
YEY1_RS00440	COG3328	transposase activity
YEY1_RS00450	COG3210	domain, Protein
YEY1_RS00455	COG2831	hemolysin activation secretion protein
YEY1_RS00475	COG2271	Major facilitator Superfamily
YEY1_RS00480	COG3851	Histidine kinase
YEY1_RS00485	COG2197	response regulator
YEY1_RS00490	COG2194	sulfuric ester hydrolase activity
YEY1_RS00495	COG1764	response to oxidative stress
YEY1_RS00510	COG0747	negative chemotaxis
YEY1_RS00515	COG0601	transmembrane transport
YEY1_RS00520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_RS00525	COG0444	Belongs to the ABC transporter superfamily
YEY1_RS00530	COG4608	Belongs to the ABC transporter superfamily
YEY1_RS00535	COG2194	sulfuric ester hydrolase activity
YEY1_RS00555	COG1192	Involved in chromosome partitioning
YEY1_RS00560	COG1215	transferase activity, transferring glycosyl groups
YEY1_RS00565	COG1215	transferase activity, transferring glycosyl groups
YEY1_RS00570	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YEY1_RS00585	COG2200	EAL domain
YEY1_RS00585	COG2199	diguanylate cyclase activity
YEY1_RS00590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YEY1_RS00605	COG1301	dicarboxylic acid transport
YEY1_RS00610	COG0612	Peptidase, M16
YEY1_RS00620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_RS00625	COG1942	4-Oxalocrotonate Tautomerase
YEY1_RS00630	COG2200	EAL domain
YEY1_RS00635	COG2982	Protein involved in outer membrane biogenesis
YEY1_RS00640	COG2134	cdp-diacylglycerol pyrophosphatase
YEY1_RS00645	COG1295	ribonuclease BN
YEY1_RS00665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_RS00670	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YEY1_RS00680	COG0742	ribosomal rna small subunit methyltransferase
YEY1_RS00695	COG0589	response to stress
YEY1_RS00705	COG0306	phosphate transporter
YEY1_RS00710	COG2081	HI0933 family
YEY1_RS00730	COG3799	methylaspartate ammonia-lyase activity
YEY1_RS00735	COG4865	methylaspartate mutase activity
YEY1_RS00745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YEY1_RS00755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YEY1_RS00755	COG1648	precorrin-2 dehydrogenase activity
YEY1_RS00760	COG0583	DNA-binding transcription factor activity
YEY1_RS00765	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_RS00765	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_RS00775	COG0561	phosphatase activity
YEY1_RS00785	COG0583	DNA-binding transcription factor activity
YEY1_RS00790	COG2814	Major facilitator Superfamily
YEY1_RS00800	COG3718	enzyme involved in inositol metabolism
YEY1_RS00810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_RS00820	COG0673	inositol 2-dehydrogenase activity
YEY1_RS00825	COG1082	Xylose isomerase domain protein TIM barrel
YEY1_RS00830	COG1247	-acetyltransferase
YEY1_RS00835	COG1741	Belongs to the pirin family
YEY1_RS00840	COG1609	Transcriptional regulator
YEY1_RS00845	COG2610	gluconate transmembrane transporter activity
YEY1_RS00850	COG3265	gluconokinase activity
YEY1_RS00855	COG2095	MarC family integral membrane protein
YEY1_RS00860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YEY1_RS00880	COG3275	phosphorelay sensor kinase activity
YEY1_RS00885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
YEY1_RS00890	COG1523	belongs to the glycosyl hydrolase 13 family
YEY1_RS00900	COG0297	glycogen (starch) synthase activity
YEY1_RS00905	COG0058	SHG alpha-glucan phosphorylase activity
YEY1_RS00910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YEY1_RS00925	COG1349	DNA-binding transcription factor activity
YEY1_RS00930	COG0705	Rhomboid family
YEY1_RS00945	COG2909	trisaccharide binding
YEY1_RS00950	COG0058	SHG alpha-glucan phosphorylase activity
YEY1_RS00955	COG1640	4-alpha-glucanotransferase
YEY1_RS00970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
YEY1_RS00970	COG0316	Belongs to the HesB IscA family
YEY1_RS00980	COG0596	Alpha beta hydrolase
YEY1_RS00995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
YEY1_RS01000	COG1918	ferrous iron import across plasma membrane
YEY1_RS01005	COG2183	response to ionizing radiation
YEY1_RS01030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YEY1_RS01050	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
YEY1_RS01060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YEY1_RS01065	COG1011	Hydrolase
YEY1_RS01075	COG0494	nUDIX hydrolase
YEY1_RS01080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YEY1_RS01105	COG4796	Type ii and iii secretion system protein
YEY1_RS01110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YEY1_RS01130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YEY1_RS01140	COG0180	Tryptophanyl-tRNA synthetase
YEY1_RS01145	COG1648	precorrin-2 dehydrogenase activity
YEY1_RS01145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YEY1_RS01160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YEY1_RS01165	COG0402	S-adenosylhomocysteine deaminase activity
YEY1_RS01170	COG0738	Major facilitator superfamily
YEY1_RS01180	COG1486	melibiose metabolic process
YEY1_RS01185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YEY1_RS01190	COG0433	COG0433 Predicted ATPase
YEY1_RS01205	COG1289	transmembrane transporter activity
YEY1_RS01215	COG1765	OsmC-like protein
YEY1_RS01220	COG3954	Phosphoribulokinase
YEY1_RS01225	COG3089	Belongs to the UPF0270 family
YEY1_RS01230	COG0429	hydrolase of the alpha beta-hydrolase fold
YEY1_RS01245	COG4521	taurine ABC transporter
YEY1_RS01255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YEY1_RS01260	COG2175	clavaminate synthase activity
YEY1_RS01270	COG1216	Glycosyl transferase, family 2
YEY1_RS01275	COG0488	(ABC) transporter
YEY1_RS01285	COG2249	NAD(P)H dehydrogenase (quinone) activity
YEY1_RS01295	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YEY1_RS01300	COG1047	Peptidyl-prolyl cis-trans
YEY1_RS01305	COG2900	Belongs to the SlyX family
YEY1_RS01310	COG0545	Peptidyl-prolyl cis-trans isomerase
YEY1_RS01315	COG2964	Protein conserved in bacteria
YEY1_RS01320	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YEY1_RS01325	COG2923	Belongs to the DsrF TusC family
YEY1_RS01330	COG2168	tRNA wobble position uridine thiolation
YEY1_RS01335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YEY1_RS01340	COG0049	tRNA binding
YEY1_RS01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YEY1_RS01370	COG0051	transcription antitermination factor activity, RNA binding
YEY1_RS01375	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YEY1_RS01380	COG0088	Forms part of the polypeptide exit tunnel
YEY1_RS01385	COG0089	rRNA binding
YEY1_RS01390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YEY1_RS01395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YEY1_RS01400	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YEY1_RS01405	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YEY1_RS01410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YEY1_RS01415	COG0255	Belongs to the universal ribosomal protein uL29 family
YEY1_RS01420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YEY1_RS01425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YEY1_RS01430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YEY1_RS01435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YEY1_RS01440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YEY1_RS01450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YEY1_RS01455	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YEY1_RS01460	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YEY1_RS01465	COG1841	ribosomal large subunit assembly
YEY1_RS01470	COG0200	Binds to the 23S rRNA
YEY1_RS01475	COG0201	protein transport
YEY1_RS01480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YEY1_RS01485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YEY1_RS01490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YEY1_RS01495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YEY1_RS01500	COG0202	RNA polymerase activity
YEY1_RS01505	COG0203	ribosomal protein L17
YEY1_RS01515	COG0789	Transcriptional regulator
YEY1_RS01520	COG3036	rescue of stalled ribosome
YEY1_RS01530	COG1970	mechanosensitive ion channel activity
YEY1_RS01540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YEY1_RS01540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YEY1_RS01550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YEY1_RS01555	COG0242	peptide deformylase activity
YEY1_RS01560	COG0758	DNA mediated transformation
YEY1_RS01570	COG0551	DNA topoisomerase type I activity
YEY1_RS01575	COG0009	L-threonylcarbamoyladenylate synthase
YEY1_RS01580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YEY1_RS01585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YEY1_RS01630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YEY1_RS01635	COG3162	membrane
YEY1_RS01640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YEY1_RS01645	COG1301	dicarboxylic acid transport
YEY1_RS01650	COG2197	response regulator
YEY1_RS01805	COG2391	methyltransferase activity
YEY1_RS01815	COG0425	Belongs to the sulfur carrier protein TusA family
YEY1_RS01830	COG3712	iron ion homeostasis
YEY1_RS01835	COG4771	TonB-dependent receptor
YEY1_RS01840	COG4178	(ABC) transporter
YEY1_RS01845	COG0612	Peptidase, M16
YEY1_RS01850	COG2161	toxin-antitoxin pair type II binding
YEY1_RS01855	COG4115	mRNA cleavage
YEY1_RS01860	COG3264	Mechanosensitive ion channel
YEY1_RS01860	COG1511	domain protein
YEY1_RS01865	COG4774	siderophore transport
YEY1_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_RS01880	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YEY1_RS01885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YEY1_RS01890	COG4558	Periplasmic binding protein
YEY1_RS01895	COG3720	iron ion transport
YEY1_RS01915	COG3721	Heme iron utilization protein
YEY1_RS01925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YEY1_RS01930	COG0814	amino acid
YEY1_RS01935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YEY1_RS01940	COG1882	Formate acetyltransferase
YEY1_RS01950	COG1309	transcriptional regulator
YEY1_RS01955	COG1929	Belongs to the glycerate kinase type-1 family
YEY1_RS01960	COG4232	protein-disulfide reductase activity
YEY1_RS01970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YEY1_RS01985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YEY1_RS01990	COG0459	protein refolding
YEY1_RS02010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YEY1_RS02030	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YEY1_RS02035	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YEY1_RS02040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YEY1_RS02045	COG1053	succinate dehydrogenase
YEY1_RS02050	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
YEY1_RS02055	COG3264	Mechanosensitive ion channel
YEY1_RS02055	COG1511	domain protein
YEY1_RS02060	COG0688	phosphatidylethanolamine metabolic process
YEY1_RS02065	COG1162	GTPase activity
YEY1_RS02070	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YEY1_RS02090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YEY1_RS02095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YEY1_RS02095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YEY1_RS02100	COG0802	atpase or kinase
YEY1_RS02105	COG0860	N-Acetylmuramoyl-L-alanine amidase
YEY1_RS02110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YEY1_RS02115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YEY1_RS02120	COG1923	regulation of RNA biosynthetic process
YEY1_RS02125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YEY1_RS02130	COG0330	HflC and HflK could
YEY1_RS02135	COG0330	HflC and HflK could
YEY1_RS02140	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YEY1_RS02145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YEY1_RS02150	COG1959	2 iron, 2 sulfur cluster binding
YEY1_RS02155	COG0557	exoribonuclease II activity
YEY1_RS02160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YEY1_RS02165	COG1960	acyl-CoA dehydrogenase activity
YEY1_RS02175	COG3650	response to hydrogen peroxide
YEY1_RS02180	COG1073	alpha beta
YEY1_RS02195	COG0360	Binds together with S18 to 16S ribosomal RNA
YEY1_RS02200	COG2965	DNA replication, synthesis of RNA primer
YEY1_RS02205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YEY1_RS02210	COG0359	binds to the 23S rRNA
YEY1_RS02220	COG3061	Opacity-associated protein A
YEY1_RS02225	COG0545	Peptidyl-prolyl cis-trans isomerase
YEY1_RS02235	COG0737	Belongs to the 5'-nucleotidase family
YEY1_RS02240	COG1218	3'(2'),5'-bisphosphate nucleotidase
YEY1_RS02245	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YEY1_RS02255	COG1253	flavin adenine dinucleotide binding
YEY1_RS02260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YEY1_RS02275	COG2911	Protein conserved in bacteria
YEY1_RS02280	COG2105	PFAM AIG2 family protein
YEY1_RS02285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YEY1_RS02295	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YEY1_RS02300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YEY1_RS02310	COG1438	arginine binding
YEY1_RS02315	COG0039	L-malate dehydrogenase activity
YEY1_RS02320	COG3423	Transcriptional regulator
YEY1_RS02330	COG0142	geranyltranstransferase activity
YEY1_RS02335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YEY1_RS02340	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YEY1_RS02345	COG0697	spore germination
YEY1_RS02350	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YEY1_RS02355	COG0642	Histidine kinase
YEY1_RS02360	COG0745	RESPONSE REGULATOR receiver
YEY1_RS02365	COG2027	D-alanyl-D-alanine carboxypeptidase
YEY1_RS02375	COG1534	Rna-binding protein
YEY1_RS02380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YEY1_RS02390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YEY1_RS02395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YEY1_RS02400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YEY1_RS02415	COG0779	Required for maturation of 30S ribosomal subunits
YEY1_RS02420	COG0195	Participates in both transcription termination and antitermination
YEY1_RS02425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YEY1_RS02430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YEY1_RS02435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YEY1_RS02440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YEY1_RS02445	COG1185	polyribonucleotide nucleotidyltransferase activity
YEY1_RS02460	COG0513	Belongs to the DEAD box helicase family
YEY1_RS02470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YEY1_RS02480	COG0814	amino acid
YEY1_RS02485	COG3681	Belongs to the UPF0597 family
YEY1_RS02490	COG0826	peptidase U32
YEY1_RS02495	COG0826	peptidase U32
YEY1_RS02500	COG3154	lipid carrier protein
YEY1_RS02505	COG3153	acetyltransferase
YEY1_RS02510	COG2827	Endonuclease containing a URI domain
YEY1_RS02515	COG0531	amino acid
YEY1_RS02520	COG1982	Orn Lys Arg decarboxylase major
YEY1_RS02540	COG1653	transport
YEY1_RS02545	COG1175	transmembrane transport
YEY1_RS02550	COG0395	ABC-type sugar transport system, permease component
YEY1_RS02555	COG3842	ATPase activity
YEY1_RS02565	COG3787	Belongs to the UPF0306 family
YEY1_RS02580	COG0702	epimerase
YEY1_RS02585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YEY1_RS02595	COG3454	Phosphonate metabolism
YEY1_RS02600	COG4778	phosphonate C-P lyase system protein PhnL
YEY1_RS02605	COG4107	phosphonate C-P lyase system protein PhnK
YEY1_RS02610	COG3627	carbon phosphorus lyase activity
YEY1_RS02620	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YEY1_RS02625	COG3624	Phosphonate C-P lyase system protein PhnG
YEY1_RS02630	COG2188	Transcriptional regulator
YEY1_RS02665	COG4608	Belongs to the ABC transporter superfamily
YEY1_RS02670	COG0444	Belongs to the ABC transporter superfamily
YEY1_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_RS02680	COG0601	transmembrane transport
YEY1_RS02690	COG2731	YhcH YjgK YiaL family protein
YEY1_RS02700	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YEY1_RS02720	COG2927	DNA polymerase III (CHI subunit)
YEY1_RS02725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YEY1_RS02730	COG0795	lipopolysaccharide-transporting ATPase activity
YEY1_RS02735	COG0795	lipopolysaccharide-transporting ATPase activity
YEY1_RS02790	COG0454	-acetyltransferase
YEY1_RS02840	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YEY1_RS02845	COG1830	Aldolase
YEY1_RS02850	COG1879	ABC-type sugar transport system periplasmic component
YEY1_RS02855	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS02860	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS02865	COG1129	ABC transporter
YEY1_RS02875	COG2390	Transcriptional regulator
YEY1_RS02880	COG1070	Carbohydrate kinase
YEY1_RS02885	COG0859	PFAM glycosyl transferase family 9
YEY1_RS02900	COG2235	arginine
YEY1_RS02910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS02915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_RS02925	COG2376	Dihydroxyacetone kinase
YEY1_RS02930	COG1461	Dihydroxyacetone kinase
YEY1_RS02935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS02935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YEY1_RS02935	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
YEY1_RS02945	COG2192	nodulation
YEY1_RS02975	COG3284	Transcriptional regulator
YEY1_RS03010	COG4772	TonB-dependent receptor
YEY1_RS03035	COG0583	DNA-binding transcription factor activity
YEY1_RS03040	COG0667	Aldo Keto reductase
YEY1_RS03045	COG2813	Specifically methylates the guanine in position
YEY1_RS03050	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YEY1_RS03055	COG0456	acetyltransferase
YEY1_RS03060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YEY1_RS03065	COG2823	Periplasmic or secreted lipoprotein
YEY1_RS03075	COG4667	esterase of the alpha-beta hydrolase superfamily
YEY1_RS03080	COG0084	hydrolase, TatD family'
YEY1_RS03085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YEY1_RS03095	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YEY1_RS03100	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YEY1_RS03105	COG0813	purine-nucleoside phosphorylase activity
YEY1_RS03110	COG3726	membrane protein affecting hemolysin expression
YEY1_RS03115	COG0560	Phosphoserine phosphatase
YEY1_RS03140	COG0604	alcohol dehydrogenase
YEY1_RS03155	COG0488	(ABC) transporter
YEY1_RS03160	COG2885	chlorophyll binding
YEY1_RS03165	COG2199	diguanylate cyclase activity
YEY1_RS03175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YEY1_RS03180	COG0741	lytic transglycosylase activity
YEY1_RS03185	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YEY1_RS03190	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
YEY1_RS03195	COG0406	alpha-ribazole phosphatase activity
YEY1_RS03200	COG2207	Transcriptional regulator
YEY1_RS03200	COG3708	Transcriptional regulator
YEY1_RS03205	COG3045	CreA protein
YEY1_RS03210	COG0745	RESPONSE REGULATOR receiver
YEY1_RS03225	COG0083	homoserine kinase activity
YEY1_RS03240	COG3022	response to hydroperoxide
YEY1_RS03245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YEY1_RS03250	COG0521	Mo-molybdopterin cofactor biosynthetic process
YEY1_RS03265	COG1584	GPR1 FUN34 yaaH family protein
YEY1_RS03270	COG0443	Heat shock 70 kDa protein
YEY1_RS03275	COG0484	heat shock protein binding
YEY1_RS03285	COG0583	DNA-binding transcription factor activity
YEY1_RS03290	COG0268	Binds directly to 16S ribosomal RNA
YEY1_RS03305	COG0196	riboflavin kinase activity
YEY1_RS03310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YEY1_RS03315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YEY1_RS03320	COG1047	Peptidyl-prolyl cis-trans
YEY1_RS03325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YEY1_RS03330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YEY1_RS03340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YEY1_RS03345	COG1280	lysine exporter protein (LysE YggA)
YEY1_RS03350	COG2966	Psort location CytoplasmicMembrane, score
YEY1_RS03355	COG3610	response to peptide
YEY1_RS03360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YEY1_RS03365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YEY1_RS03370	COG2967	ApaG domain
YEY1_RS03375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YEY1_RS03390	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YEY1_RS03395	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YEY1_RS03400	COG0564	pseudouridine synthase activity
YEY1_RS03405	COG1388	LysM domain
YEY1_RS03405	COG1470	cell adhesion involved in biofilm formation
YEY1_RS03410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YEY1_RS03415	COG0417	DNA replication proofreading
YEY1_RS03420	COG0586	Pfam SNARE associated Golgi protein
YEY1_RS03430	COG1178	ABC-type Fe3 transport system permease component
YEY1_RS03435	COG4143	(ABC) transporter
YEY1_RS03450	COG4533	DNA binding
YEY1_RS03455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YEY1_RS03460	COG1882	Formate acetyltransferase
YEY1_RS03465	COG2814	Major facilitator Superfamily
YEY1_RS03470	COG0814	amino acid
YEY1_RS03490	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YEY1_RS03495	COG0473	3-isopropylmalate dehydrogenase activity
YEY1_RS03500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YEY1_RS03515	COG1022	Amp-dependent synthetase and ligase
YEY1_RS03520	COG0028	Belongs to the TPP enzyme family
YEY1_RS03540	COG2001	Belongs to the MraZ family
YEY1_RS03545	COG0275	rRNA processing
YEY1_RS03550	COG3116	cell division
YEY1_RS03555	COG0768	penicillin binding
YEY1_RS03560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YEY1_RS03565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YEY1_RS03570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YEY1_RS03580	COG0772	Belongs to the SEDS family
YEY1_RS03585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YEY1_RS03590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YEY1_RS03600	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YEY1_RS03605	COG0849	cell division
YEY1_RS03610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YEY1_RS03630	COG0653	protein targeting
YEY1_RS03635	COG0494	nUDIX hydrolase
YEY1_RS03640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YEY1_RS03660	COG0516	GMP reductase activity
YEY1_RS03665	COG1459	type II secretion system
YEY1_RS03670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YEY1_RS03675	COG4969	Belongs to the N-Me-Phe pilin family
YEY1_RS03690	COG3725	Membrane protein required for beta-lactamase induction
YEY1_RS03695	COG1113	amino acid transport
YEY1_RS03700	COG2186	Transcriptional regulator
YEY1_RS03705	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YEY1_RS03710	COG0508	dehydrogenase complex catalyzes the overall conversion of
YEY1_RS03715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_RS03725	COG4977	sequence-specific DNA binding
YEY1_RS03740	COG3112	Uncharacterised protein family (UPF0231)
YEY1_RS03755	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YEY1_RS03760	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YEY1_RS03770	COG2132	Multicopper oxidase
YEY1_RS03780	COG0288	reversible hydration of carbon dioxide
YEY1_RS03785	COG1131	(ABC) transporter
YEY1_RS03790	COG0842	Transport permease protein
YEY1_RS03795	COG0726	polysaccharide deacetylase
YEY1_RS03800	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YEY1_RS03805	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YEY1_RS03810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YEY1_RS03815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YEY1_RS03840	COG1489	DNA binding
YEY1_RS03845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YEY1_RS03850	COG1643	Atp-dependent helicase
YEY1_RS03855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YEY1_RS03860	COG1120	ATPase activity
YEY1_RS03865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YEY1_RS03870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YEY1_RS03875	COG2223	nitrite transmembrane transporter activity
YEY1_RS03880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YEY1_RS03890	COG0316	Belongs to the HesB IscA family
YEY1_RS03895	COG2860	membrane
YEY1_RS03905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YEY1_RS03910	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YEY1_RS03915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YEY1_RS03920	COG3437	response regulator, receiver
YEY1_RS03920	COG2205	protein histidine kinase activity
YEY1_RS03920	COG3850	Histidine kinase
YEY1_RS03920	COG4999	Histidine kinase
YEY1_RS03925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YEY1_RS03930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YEY1_RS03935	COG3956	TIGRFAM MazG family protein
YEY1_RS03940	COG0504	CTP synthase activity
YEY1_RS03945	COG0148	phosphopyruvate hydratase activity
YEY1_RS03950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YEY1_RS03960	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
YEY1_RS03970	COG3079	Belongs to the UPF0149 family
YEY1_RS03975	COG0006	proline dipeptidase activity
YEY1_RS03980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YEY1_RS03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YEY1_RS03990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YEY1_RS03995	COG0509	glycine decarboxylation via glycine cleavage system
YEY1_RS04000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YEY1_RS04000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YEY1_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS04020	COG1272	protein, Hemolysin III
YEY1_RS04030	COG0354	folic acid binding
YEY1_RS04045	COG0745	RESPONSE REGULATOR receiver
YEY1_RS04055	COG4452	Inner membrane protein CreD
YEY1_RS04060	COG0716	FMN binding
YEY1_RS04065	COG4974	Belongs to the 'phage' integrase family
YEY1_RS04070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YEY1_RS04075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YEY1_RS04085	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YEY1_RS04120	COG2944	sequence-specific DNA binding
YEY1_RS04125	COG3328	transposase activity
YEY1_RS04140	COG4319	ketosteroid isomerase
YEY1_RS04145	COG3706	GGDEF domain
YEY1_RS04160	COG0484	heat shock protein binding
YEY1_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS04175	COG1733	regulation of RNA biosynthetic process
YEY1_RS04180	COG0288	reversible hydration of carbon dioxide
YEY1_RS04205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YEY1_RS04215	COG2165	general secretion pathway protein
YEY1_RS04255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
YEY1_RS04295	COG2814	Major facilitator Superfamily
YEY1_RS04300	COG0583	DNA-binding transcription factor activity
YEY1_RS04310	COG1609	Transcriptional regulator
YEY1_RS04330	COG0204	Acyl-transferase
YEY1_RS04330	COG0318	PFAM AMP-dependent synthetase and ligase
YEY1_RS04335	COG0477	Major facilitator Superfamily
YEY1_RS04340	COG0667	Aldo Keto reductase
YEY1_RS04345	COG0861	Integral membrane protein TerC family
YEY1_RS04350	COG3066	DNA modification
YEY1_RS04355	COG1051	belongs to the nudix hydrolase family
YEY1_RS04365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YEY1_RS04370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YEY1_RS04375	COG2165	general secretion pathway protein
YEY1_RS04390	COG4967	type IV pilus modification protein PilV
YEY1_RS04395	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YEY1_RS04400	COG1025	Belongs to the peptidase M16 family
YEY1_RS04405	COG1074	ATP-dependent DNA helicase activity
YEY1_RS04410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YEY1_RS04420	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
YEY1_RS04425	COG2363	Small membrane protein
YEY1_RS04430	COG0583	DNA-binding transcription factor activity
YEY1_RS04445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YEY1_RS04450	COG2166	iron-sulfur cluster assembly
YEY1_RS04455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YEY1_RS04460	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YEY1_RS04480	COG0860	N-Acetylmuramoyl-L-alanine amidase
YEY1_RS04485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YEY1_RS04485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YEY1_RS04500	COG3328	transposase activity
YEY1_RS04505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YEY1_RS04510	COG1611	Belongs to the LOG family
YEY1_RS04515	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YEY1_RS04515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YEY1_RS04525	COG3098	single-species biofilm formation
YEY1_RS04530	COG0564	pseudouridine synthase activity
YEY1_RS04545	COG2171	N-acyltransferase activity
YEY1_RS04550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YEY1_RS04565	COG0052	Belongs to the universal ribosomal protein uS2 family
YEY1_RS04570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YEY1_RS04575	COG0528	UMP kinase activity
YEY1_RS04580	COG0233	cytoplasmic translational termination
YEY1_RS04585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YEY1_RS04595	COG0575	Belongs to the CDS family
YEY1_RS04600	COG0750	zinc metalloprotease
YEY1_RS04610	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YEY1_RS04615	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_RS04620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YEY1_RS04625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_RS04635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YEY1_RS04645	COG0825	malonyl-CoA metabolic process
YEY1_RS04650	COG1982	Orn Lys Arg decarboxylase major
YEY1_RS04655	COG0346	lactoylglutathione lyase activity
YEY1_RS04670	COG4568	rho-dependent transcription termination
YEY1_RS04680	COG4681	YaeQ
YEY1_RS04690	COG3015	lipoprotein NlpE involved in copper resistance
YEY1_RS04695	COG0442	prolyl-tRNA aminoacylation
YEY1_RS04700	COG1720	tRNA m6t6A37 methyltransferase activity
YEY1_RS04710	COG1464	Belongs to the NlpA lipoprotein family
YEY1_RS04715	COG2011	ABC-type metal ion transport system permease component
YEY1_RS04725	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YEY1_RS04760	COG3328	transposase activity
YEY1_RS04770	COG0656	L-ascorbic acid biosynthetic process
YEY1_RS04775	COG0583	DNA-binding transcription factor activity
YEY1_RS04780	COG2814	Major facilitator Superfamily
YEY1_RS04785	COG3021	interspecies interaction between organisms
YEY1_RS04795	COG1388	LysM domain
YEY1_RS04795	COG0741	lytic transglycosylase activity
YEY1_RS04800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YEY1_RS04805	COG2226	methyltransferase
YEY1_RS04810	COG0328	RNA-DNA hybrid ribonuclease activity
YEY1_RS04825	COG2113	Glycine betaine
YEY1_RS04830	COG4176	ABC-type proline glycine betaine transport system permease component
YEY1_RS04840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YEY1_RS04850	COG1780	Probably involved in ribonucleotide reductase function
YEY1_RS04860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YEY1_RS04870	COG4575	ribosome binding
YEY1_RS04885	COG2207	Transcriptional regulator
YEY1_RS04910	COG1278	Cold shock
YEY1_RS04945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_RS04955	COG1124	(ABC) transporter
YEY1_RS04965	COG0831	urea catabolic process
YEY1_RS04970	COG0832	Belongs to the urease beta subunit family
YEY1_RS04975	COG0804	urea catabolic process
YEY1_RS04980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
YEY1_RS04985	COG0830	nickel cation binding
YEY1_RS04990	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YEY1_RS04995	COG0829	nickel cation binding
YEY1_RS05000	COG4413	Urea transporter
YEY1_RS05005	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YEY1_RS05015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YEY1_RS05030	COG0667	Aldo Keto reductase
YEY1_RS05040	COG2133	pyrroloquinoline quinone binding
YEY1_RS05045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_RS05050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_RS05055	COG2723	6-phospho-beta-galactosidase activity
YEY1_RS05060	COG1447	Phosphotransferase system cellobiose-specific component IIA
YEY1_RS05065	COG1917	Cupin 2, conserved barrel domain protein
YEY1_RS05065	COG2169	Transcriptional regulator
YEY1_RS05070	COG3394	polysaccharide catabolic process
YEY1_RS05075	COG0659	secondary active sulfate transmembrane transporter activity
YEY1_RS05085	COG3328	transposase activity
YEY1_RS05090	COG0582	viral genome integration into host DNA
YEY1_RS05100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YEY1_RS05105	COG2867	negative regulation of translational initiation
YEY1_RS05115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YEY1_RS05120	COG0497	DNA recombination
YEY1_RS05125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YEY1_RS05130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YEY1_RS05135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YEY1_RS05140	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
YEY1_RS05170	COG0513	Belongs to the DEAD box helicase family
YEY1_RS05175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
YEY1_RS05180	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YEY1_RS05190	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YEY1_RS05200	COG3086	response to oxidative stress
YEY1_RS05210	COG0481	GTPase activity
YEY1_RS05220	COG0571	ribonuclease III activity
YEY1_RS05225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YEY1_RS05230	COG1381	Involved in DNA repair and RecF pathway recombination
YEY1_RS05235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YEY1_RS05240	COG0736	holo-[acyl-carrier-protein] synthase activity
YEY1_RS05250	COG2610	gluconate transmembrane transporter activity
YEY1_RS05255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YEY1_RS05260	COG1737	Transcriptional regulator
YEY1_RS05270	COG0560	Phosphoserine phosphatase
YEY1_RS05285	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YEY1_RS05300	COG2205	protein histidine kinase activity
YEY1_RS05305	COG3170	Tfp pilus assembly protein FimV
YEY1_RS05310	COG2204	response regulator
YEY1_RS05315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YEY1_RS05315	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YEY1_RS05320	COG0347	Belongs to the P(II) protein family
YEY1_RS05335	COG1735	metal-dependent hydrolase with the TIM-barrel fold
YEY1_RS05340	COG3457	Alanine racemase
YEY1_RS05350	COG2188	Transcriptional regulator
YEY1_RS05355	COG1017	nitric oxide dioxygenase activity
YEY1_RS05355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YEY1_RS05360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YEY1_RS05365	COG2814	Major facilitator Superfamily
YEY1_RS05370	COG3711	transcriptional antiterminator
YEY1_RS05375	COG3683	transport system, periplasmic component
YEY1_RS05380	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YEY1_RS05390	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
YEY1_RS05395	COG1959	2 iron, 2 sulfur cluster binding
YEY1_RS05405	COG0822	iron-sulfur transferase activity
YEY1_RS05410	COG0316	Belongs to the HesB IscA family
YEY1_RS05415	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YEY1_RS05420	COG0443	Heat shock 70 kDa protein
YEY1_RS05425	COG0633	Ferredoxin
YEY1_RS05430	COG2975	iron-sulfur cluster assembly
YEY1_RS05455	COG2373	Large extracellular alpha-helical protein
YEY1_RS05460	COG4953	penicillin-binding protein 1C
YEY1_RS05475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YEY1_RS05485	COG1426	Protein conserved in bacteria
YEY1_RS05490	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YEY1_RS05495	COG0124	histidyl-tRNA synthetase
YEY1_RS05500	COG2976	Protein conserved in bacteria
YEY1_RS05505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YEY1_RS05515	COG1160	GTP binding
YEY1_RS05530	COG1645	bacterial-type flagellum-dependent swarming motility
YEY1_RS05535	COG1570	exodeoxyribonuclease VII activity
YEY1_RS05545	COG0517	IMP dehydrogenase activity
YEY1_RS05545	COG0516	GMP reductase activity
YEY1_RS05550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YEY1_RS05550	COG0519	Catalyzes the synthesis of GMP from XMP
YEY1_RS05590	COG0351	phosphomethylpyrimidine kinase
YEY1_RS05610	COG1349	DNA-binding transcription factor activity
YEY1_RS05615	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS05635	COG3730	PTS system glucitol sorbitol-specific
YEY1_RS05640	COG1597	lipid kinase activity
YEY1_RS05645	COG0826	peptidase U32
YEY1_RS05650	COG3422	double-strand break repair
YEY1_RS05655	COG0745	RESPONSE REGULATOR receiver
YEY1_RS05660	COG2205	protein histidine kinase activity
YEY1_RS05665	COG0477	Major facilitator Superfamily
YEY1_RS05670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_RS05680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS05695	COG0443	Heat shock 70 kDa protein
YEY1_RS05700	COG5002	protein histidine kinase activity
YEY1_RS05700	COG5001	Diguanylate cyclase
YEY1_RS05700	COG3447	MASE1 domain protein
YEY1_RS05710	COG0581	inorganic phosphate transmembrane transporter activity
YEY1_RS05715	COG0573	inorganic phosphate transmembrane transporter activity
YEY1_RS05720	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YEY1_RS05735	COG2239	Acts as a magnesium transporter
YEY1_RS05740	COG3447	MASE1 domain protein
YEY1_RS05740	COG5001	Diguanylate cyclase
YEY1_RS05740	COG5002	protein histidine kinase activity
YEY1_RS05750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YEY1_RS05755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YEY1_RS05760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YEY1_RS05765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YEY1_RS05770	COG2233	PERMEase
YEY1_RS05775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YEY1_RS05780	COG1393	Belongs to the ArsC family
YEY1_RS05785	COG4783	chaperone-mediated protein folding
YEY1_RS05790	COG0628	permease
YEY1_RS05800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YEY1_RS05805	COG2716	regulation of RNA biosynthetic process
YEY1_RS05810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YEY1_RS05815	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YEY1_RS05820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YEY1_RS05825	COG2321	neutral zinc metallopeptidase
YEY1_RS05830	COG2707	UPF0756 membrane protein
YEY1_RS05835	COG1444	tRNA N-acetyltransferase activity
YEY1_RS05850	COG0400	carboxylic ester hydrolase activity
YEY1_RS05900	COG1876	peptidase activity
YEY1_RS05905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YEY1_RS05910	COG1393	Belongs to the ArsC family
YEY1_RS05925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_RS05935	COG2197	response regulator
YEY1_RS05945	COG3062	negative regulation of establishment of protein localization
YEY1_RS05950	COG0243	molybdopterin cofactor binding
YEY1_RS05955	COG3043	anaerobic respiration
YEY1_RS05960	COG3005	denitrification pathway
YEY1_RS05965	COG0494	nUDIX hydrolase
YEY1_RS05975	COG0280	phosphate acetyltransferase
YEY1_RS05975	COG0281	malic enzyme
YEY1_RS06000	COG2259	Doxx family
YEY1_RS06010	COG1560	Kdo2-lipid A biosynthetic process
YEY1_RS06040	COG1054	Belongs to the UPF0176 family
YEY1_RS06045	COG0628	permease
YEY1_RS06075	COG0418	dihydroorotase activity
YEY1_RS06080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YEY1_RS06085	COG1530	ribonuclease E activity
YEY1_RS06085	COG1530	ribonuclease E activity
YEY1_RS06095	COG0564	pseudouridine synthase activity
YEY1_RS06100	COG0424	maF-like protein
YEY1_RS06105	COG1399	metal-binding, possibly nucleic acid-binding protein
YEY1_RS06110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YEY1_RS06115	COG0416	fatty acid biosynthetic process
YEY1_RS06120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YEY1_RS06125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YEY1_RS06130	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS06140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YEY1_RS06150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YEY1_RS06155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YEY1_RS06160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YEY1_RS06165	COG0470	DNA polymerase III
YEY1_RS06170	COG0084	hydrolase, TatD family'
YEY1_RS06175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS06175	COG1263	PTS System
YEY1_RS06195	COG0641	radical SAM
YEY1_RS06210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YEY1_RS06215	COG0537	adenosine 5'-monophosphoramidase activity
YEY1_RS06220	COG5633	Lipoprotein
YEY1_RS06225	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
YEY1_RS06235	COG1472	Belongs to the glycosyl hydrolase 3 family
YEY1_RS06240	COG3150	esterase
YEY1_RS06245	COG1252	NADH dehydrogenase
YEY1_RS06250	COG3134	Outer membrane lipoprotein
YEY1_RS06255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YEY1_RS06260	COG4591	ABC-type transport system involved in lipoprotein release permease component
YEY1_RS06270	COG4591	ABC-type transport system involved in lipoprotein release permease component
YEY1_RS06275	COG1940	carbohydrate kinase activity
YEY1_RS06290	COG2850	peptidyl-arginine hydroxylation
YEY1_RS06300	COG0745	RESPONSE REGULATOR receiver
YEY1_RS06310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YEY1_RS06315	COG2915	High frequency lysogenization protein hflD homolog
YEY1_RS06320	COG0482	sulfurtransferase activity
YEY1_RS06330	COG1187	pseudouridine synthase activity
YEY1_RS06335	COG0538	isocitrate dehydrogenase activity
YEY1_RS06395	COG0840	transmembrane signaling receptor activity
YEY1_RS06415	COG2873	o-acetylhomoserine
YEY1_RS06420	COG0702	epimerase
YEY1_RS06425	COG1733	regulation of RNA biosynthetic process
YEY1_RS06475	COG3706	GGDEF domain
YEY1_RS06475	COG4251	negative regulation of phosphorylation
YEY1_RS06475	COG5001	Diguanylate cyclase
YEY1_RS06475	COG2203	Gaf domain
YEY1_RS06495	COG1132	(ABC) transporter
YEY1_RS06515	COG2207	Transcriptional regulator
YEY1_RS06520	COG3328	transposase activity
YEY1_RS06555	COG1113	amino acid transport
YEY1_RS06575	COG1496	oxidoreductase activity
YEY1_RS06585	COG2226	methyltransferase
YEY1_RS06595	COG3447	MASE1 domain protein
YEY1_RS06595	COG5001	Diguanylate cyclase
YEY1_RS06595	COG5002	protein histidine kinase activity
YEY1_RS06605	COG1971	Probably functions as a manganese efflux pump
YEY1_RS06610	COG4811	Protein of unknown function (DUF986)
YEY1_RS06615	COG3716	PTS system mannose fructose sorbose family IID component
YEY1_RS06620	COG3715	PTS system
YEY1_RS06625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS06625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS06630	COG1253	flavin adenine dinucleotide binding
YEY1_RS06640	COG1760	l-serine dehydratase
YEY1_RS06645	COG0494	nUDIX hydrolase
YEY1_RS06655	COG3140	Belongs to the UPF0181 family
YEY1_RS06660	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
YEY1_RS06665	COG0513	Belongs to the DEAD box helicase family
YEY1_RS06670	COG3141	response to X-ray
YEY1_RS06675	COG3097	Belongs to the UPF0267 family
YEY1_RS06685	COG1770	oligopeptidase
YEY1_RS06690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YEY1_RS06705	COG1528	Iron-storage protein
YEY1_RS06710	COG2372	response to copper ion
YEY1_RS06715	COG1276	copper resistance
YEY1_RS06725	COG4974	Belongs to the 'phage' integrase family
YEY1_RS06775	COG3328	transposase activity
YEY1_RS06780	COG0500	methyltransferase
YEY1_RS06790	COG3328	transposase activity
YEY1_RS06805	COG0561	phosphatase activity
YEY1_RS06810	COG2223	nitrite transmembrane transporter activity
YEY1_RS06830	COG3493	citrate carrier protein
YEY1_RS06835	COG4565	transcriptional regulatory protein
YEY1_RS06840	COG3290	protein histidine kinase activity
YEY1_RS06845	COG1349	DNA-binding transcription factor activity
YEY1_RS06850	COG3395	kinase activity
YEY1_RS06860	COG3622	Belongs to the hyi family
YEY1_RS06865	COG2066	Belongs to the glutaminase family
YEY1_RS06880	COG0672	)-iron permease
YEY1_RS06895	COG1136	(ABC) transporter
YEY1_RS06895	COG0577	efflux transmembrane transporter activity
YEY1_RS06905	COG1136	(ABC) transporter
YEY1_RS06905	COG0577	efflux transmembrane transporter activity
YEY1_RS06930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YEY1_RS06935	COG4114	ferric iron reductase
YEY1_RS06940	COG0006	proline dipeptidase activity
YEY1_RS06950	COG0726	polysaccharide deacetylase
YEY1_RS06950	COG1649	PFAM Uncharacterised BCR, COG1649
YEY1_RS06955	COG1215	transferase activity, transferring glycosyl groups
YEY1_RS06960	COG3658	cytochrome
YEY1_RS06975	COG1702	phosphate starvation-inducible protein PhoH
YEY1_RS06985	COG0018	arginyl-trna synthetase
YEY1_RS06990	COG3102	Protein conserved in bacteria
YEY1_RS06995	COG3142	Participates in the control of copper homeostasis
YEY1_RS07015	COG0668	transmembrane transport
YEY1_RS07020	COG0625	glutathione transferase activity
YEY1_RS07045	COG5001	Diguanylate cyclase
YEY1_RS07090	COG3008	intermembrane lipid transfer
YEY1_RS07095	COG2995	paraquat-inducible protein a
YEY1_RS07100	COG1956	GAF domain-containing protein
YEY1_RS07110	COG0793	Belongs to the peptidase S41A family
YEY1_RS07115	COG0501	Belongs to the peptidase M48B family
YEY1_RS07125	COG2814	Major facilitator Superfamily
YEY1_RS07130	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_RS07140	COG3023	N-Acetylmuramoyl-L-alanine amidase
YEY1_RS07155	COG1988	membrane-bound metal-dependent
YEY1_RS07165	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YEY1_RS07170	COG1653	transport
YEY1_RS07175	COG3842	ATPase activity
YEY1_RS07180	COG0395	ABC-type sugar transport system, permease component
YEY1_RS07185	COG1175	transmembrane transport
YEY1_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS07200	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
YEY1_RS07205	COG1917	Cupin 2, conserved barrel domain protein
YEY1_RS07210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_RS07220	COG0583	DNA-binding transcription factor activity
YEY1_RS07225	COG0427	acetyl-CoA hydrolase
YEY1_RS07230	COG1024	Enoyl-CoA hydratase
YEY1_RS07235	COG1703	isobutyryl-CoA mutase activity
YEY1_RS07240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YEY1_RS07240	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YEY1_RS07245	COG3001	Fructosamine kinase
YEY1_RS07255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_RS07260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_RS07265	COG1121	(ABC) transporter
YEY1_RS07270	COG0803	Belongs to the bacterial solute-binding protein 9 family
YEY1_RS07310	COG1811	Na channel or pump
YEY1_RS07315	COG4249	Peptidase C14 caspase catalytic subunit p20
YEY1_RS07320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YEY1_RS07325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YEY1_RS07330	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YEY1_RS07335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YEY1_RS07345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YEY1_RS07355	COG0776	regulation of translation
YEY1_RS07360	COG2314	TM2 domain
YEY1_RS07370	COG4139	cobalamin transport
YEY1_RS07375	COG0386	Belongs to the glutathione peroxidase family
YEY1_RS07380	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YEY1_RS07385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YEY1_RS07390	COG0463	Glycosyl transferase, family 2
YEY1_RS07395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YEY1_RS07395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_RS07400	COG0726	polysaccharide deacetylase
YEY1_RS07405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YEY1_RS07410	COG2076	Multidrug Resistance protein
YEY1_RS07415	COG2076	Multidrug Resistance protein
YEY1_RS07420	COG0791	NLP P60 protein
YEY1_RS07425	COG0095	Lipoate-protein ligase
YEY1_RS07435	COG4558	Periplasmic binding protein
YEY1_RS07440	COG3720	iron ion transport
YEY1_RS07460	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YEY1_RS07465	COG0574	Belongs to the PEP-utilizing enzyme family
YEY1_RS07465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YEY1_RS07475	COG0628	permease
YEY1_RS07480	COG0277	FAD linked oxidase domain protein
YEY1_RS07480	COG0247	lactate metabolic process
YEY1_RS07490	COG2050	protein possibly involved in aromatic compounds catabolism
YEY1_RS07495	COG0316	Belongs to the HesB IscA family
YEY1_RS07500	COG0719	Fe-S assembly protein
YEY1_RS07505	COG0396	ATPase activity
YEY1_RS07510	COG0719	Fe-S assembly protein
YEY1_RS07520	COG2166	iron-sulfur cluster assembly
YEY1_RS07525	COG1388	LysM domain
YEY1_RS07525	COG1376	ErfK ybiS ycfS ynhG family protein
YEY1_RS07550	COG0534	Mate efflux family protein
YEY1_RS07555	COG0307	riboflavin synthase, alpha
YEY1_RS07560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YEY1_RS07565	COG2814	Major facilitator Superfamily
YEY1_RS07570	COG0583	DNA-binding transcription factor activity
YEY1_RS07575	COG1609	Transcriptional regulator
YEY1_RS07590	COG0791	NLP P60 protein
YEY1_RS07595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YEY1_RS07605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YEY1_RS07620	COG0346	lactoylglutathione lyase activity
YEY1_RS07625	COG1902	pentaerythritol trinitrate reductase activity
YEY1_RS07630	COG1309	transcriptional regulator
YEY1_RS07635	COG2194	sulfuric ester hydrolase activity
YEY1_RS07640	COG3313	Fe-S protein
YEY1_RS07645	COG4989	oxidoreductase activity
YEY1_RS07650	COG1289	transmembrane transporter activity
YEY1_RS07655	COG1566	PFAM secretion protein HlyD family protein
YEY1_RS07665	COG1846	Transcriptional regulator
YEY1_RS07670	COG3133	Outer membrane lipoprotein
YEY1_RS07675	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YEY1_RS07680	COG3895	Periplasmic Protein
YEY1_RS07685	COG0259	pyridoxamine-phosphate oxidase activity
YEY1_RS07690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YEY1_RS07700	COG0625	glutathione transferase activity
YEY1_RS07720	COG3104	oligopeptide transport
YEY1_RS07730	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YEY1_RS07730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YEY1_RS07740	COG4172	Belongs to the ABC transporter superfamily
YEY1_RS07750	COG4171	peptide transport system, permease
YEY1_RS07755	COG4168	peptide transport system, permease
YEY1_RS07760	COG4166	transmembrane transport
YEY1_RS07790	COG1349	DNA-binding transcription factor activity
YEY1_RS07795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YEY1_RS07800	COG2879	small protein
YEY1_RS07805	COG1966	Carbon starvation protein
YEY1_RS07810	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YEY1_RS07820	COG0243	molybdopterin cofactor binding
YEY1_RS07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YEY1_RS07850	COG4659	FMN binding
YEY1_RS07855	COG4658	electron transport chain
YEY1_RS07860	COG3708	Transcriptional regulator
YEY1_RS07860	COG2207	Transcriptional regulator
YEY1_RS07870	COG4656	Part of a membrane complex involved in electron transport
YEY1_RS07880	COG4657	Part of a membrane complex involved in electron transport
YEY1_RS07890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
YEY1_RS07900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS07910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YEY1_RS07915	COG2160	L-arabinose isomerase activity
YEY1_RS07925	COG1879	ABC-type sugar transport system periplasmic component
YEY1_RS07930	COG1129	ABC transporter
YEY1_RS07935	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS07945	COG0673	inositol 2-dehydrogenase activity
YEY1_RS07950	COG0385	Bile acid
YEY1_RS07955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YEY1_RS07960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YEY1_RS07980	COG5339	Protein conserved in bacteria
YEY1_RS07990	COG0114	fumarate hydratase activity
YEY1_RS08025	COG2814	Major facilitator Superfamily
YEY1_RS08030	COG0583	DNA-binding transcription factor activity
YEY1_RS08035	COG1940	carbohydrate kinase activity
YEY1_RS08040	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YEY1_RS08070	COG1742	UPF0060 membrane protein
YEY1_RS08075	COG4221	oxidoreductase activity
YEY1_RS08180	COG0625	glutathione transferase activity
YEY1_RS08210	COG1522	sequence-specific DNA binding
YEY1_RS08250	COG3177	Filamentation induced by cAMP protein fic
YEY1_RS08260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YEY1_RS08270	COG0483	inositol monophosphate 1-phosphatase activity
YEY1_RS08305	COG3023	N-Acetylmuramoyl-L-alanine amidase
YEY1_RS08320	COG0028	Belongs to the TPP enzyme family
YEY1_RS08325	COG0440	acetolactate synthase activity
YEY1_RS08330	COG1011	Hydrolase
YEY1_RS08350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_RS08360	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS08365	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
YEY1_RS08380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YEY1_RS08385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YEY1_RS08390	COG0589	response to stress
YEY1_RS08395	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YEY1_RS08400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YEY1_RS08415	COG0531	amino acid
YEY1_RS08425	COG0745	RESPONSE REGULATOR receiver
YEY1_RS08430	COG2205	protein histidine kinase activity
YEY1_RS08445	COG3591	Belongs to the peptidase S1B family
YEY1_RS08460	COG1643	Atp-dependent helicase
YEY1_RS08465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YEY1_RS08470	COG3784	Protein of unknown function (DUF1318)
YEY1_RS08480	COG2911	Protein conserved in bacteria
YEY1_RS08485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YEY1_RS08490	COG3042	response to heat
YEY1_RS08495	COG1285	pathogenesis
YEY1_RS08505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS08505	COG0674	pyruvate-flavodoxin oxidoreductase activity
YEY1_RS08505	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YEY1_RS08505	COG1013	pyruvate-flavodoxin oxidoreductase activity
YEY1_RS08510	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_RS08515	COG0037	tRNA processing
YEY1_RS08520	COG0598	Magnesium transport protein CorA
YEY1_RS08525	COG4166	transmembrane transport
YEY1_RS08530	COG2866	Carboxypeptidase
YEY1_RS08535	COG4948	Mandelate Racemase Muconate Lactonizing
YEY1_RS08540	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YEY1_RS08560	COG3768	UPF0283 membrane protein
YEY1_RS08565	COG3106	COG3106 Predicted ATPase
YEY1_RS08575	COG1983	PspC domain protein
YEY1_RS08585	COG1842	Phage shock protein A
YEY1_RS08590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YEY1_RS08615	COG0023	Translation Initiation Factor
YEY1_RS08620	COG0284	orotidine-5'-phosphate decarboxylase activity
YEY1_RS08635	COG1396	sequence-specific DNA binding
YEY1_RS08645	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YEY1_RS08650	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YEY1_RS08655	COG0671	phosphoesterase, PA-phosphatase related
YEY1_RS08675	COG0583	DNA-binding transcription factor activity
YEY1_RS08690	COG0616	signal peptide processing
YEY1_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS08700	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YEY1_RS08710	COG1187	pseudouridine synthase activity
YEY1_RS08715	COG0009	L-threonylcarbamoyladenylate synthase
YEY1_RS08720	COG0613	PHP domain protein
YEY1_RS08735	COG0512	Glutamine amidotransferase of anthranilate synthase
YEY1_RS08745	COG0134	indole-3-glycerol-phosphate synthase activity
YEY1_RS08745	COG0135	phosphoribosylanthranilate isomerase activity
YEY1_RS08750	COG0133	tryptophan synthase activity
YEY1_RS08755	COG0159	tryptophan synthase activity
YEY1_RS08765	COG3047	cAMP biosynthetic process
YEY1_RS08770	COG0727	PFAM Uncharacterised protein family (UPF0153)
YEY1_RS08785	COG2917	probably involved in intracellular septation
YEY1_RS08790	COG1607	acyl-coa hydrolase
YEY1_RS08795	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YEY1_RS08800	COG2350	Protein conserved in bacteria
YEY1_RS08825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YEY1_RS08830	COG3099	Belongs to the UPF0263 family
YEY1_RS08840	COG0444	Belongs to the ABC transporter superfamily
YEY1_RS08845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YEY1_RS08865	COG2095	MarC family integral membrane protein
YEY1_RS08875	COG1012	belongs to the aldehyde dehydrogenase family
YEY1_RS08875	COG1454	alcohol dehydrogenase
YEY1_RS08890	COG2916	Histone family protein nucleoid-structuring protein H-NS
YEY1_RS08905	COG1752	Esterase of the alpha-beta hydrolase superfamily
YEY1_RS08915	COG3012	SEC-C Motif Domain Protein
YEY1_RS08920	COG0788	formyltetrahydrofolate deformylase activity
YEY1_RS08935	COG0583	DNA-binding transcription factor activity
YEY1_RS08940	COG0708	Exodeoxyribonuclease III
YEY1_RS08945	COG0494	nUDIX hydrolase
YEY1_RS08955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YEY1_RS08965	COG0778	Nitroreductase
YEY1_RS08970	COG0616	signal peptide processing
YEY1_RS08975	COG0252	asparaginase activity
YEY1_RS08980	COG1335	isochorismatase
YEY1_RS08990	COG3139	Protein of unknown function (DUF1315)
YEY1_RS08995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YEY1_RS09010	COG3713	MltA-interacting MipA family protein
YEY1_RS09020	COG2766	serine protein kinase
YEY1_RS09025	COG2718	Belongs to the UPF0229 family
YEY1_RS09040	COG0583	DNA-binding transcription factor activity
YEY1_RS09050	COG2200	EAL domain
YEY1_RS09050	COG2199	diguanylate cyclase activity
YEY1_RS09050	COG2202	Pas domain
YEY1_RS09055	COG2814	Major facilitator Superfamily
YEY1_RS09060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YEY1_RS09065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YEY1_RS09070	COG2719	SpoVR family
YEY1_RS09075	COG2186	Transcriptional regulator
YEY1_RS09080	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YEY1_RS09085	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YEY1_RS09105	COG2983	Belongs to the UPF0260 family
YEY1_RS09110	COG0179	Fumarylacetoacetate (FAA) hydrolase
YEY1_RS09115	COG2951	lytic endotransglycosylase activity
YEY1_RS09120	COG3100	YcgL domain-containing protein
YEY1_RS09130	COG0850	regulation of cytokinetic process
YEY1_RS09135	COG2894	cell division
YEY1_RS09140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YEY1_RS09145	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YEY1_RS09150	COG0318	PFAM AMP-dependent synthetase and ligase
YEY1_RS09155	COG3065	identical protein binding
YEY1_RS09165	COG1199	ATP-dependent helicase activity
YEY1_RS09170	COG0251	oxidation-reduction process
YEY1_RS09175	COG2076	Multidrug Resistance protein
YEY1_RS09180	COG2076	Multidrug Resistance protein
YEY1_RS09190	COG0800	Aldolase
YEY1_RS09195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YEY1_RS09200	COG1737	Transcriptional regulator
YEY1_RS09205	COG0469	pyruvate kinase activity
YEY1_RS09215	COG1560	Kdo2-lipid A biosynthetic process
YEY1_RS09220	COG0739	heme binding
YEY1_RS09225	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YEY1_RS09230	COG1121	(ABC) transporter
YEY1_RS09235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_RS09240	COG3104	oligopeptide transport
YEY1_RS09245	COG2255	four-way junction helicase activity
YEY1_RS09250	COG0632	four-way junction helicase activity
YEY1_RS09255	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YEY1_RS09265	COG0217	transcriptional regulatory protein
YEY1_RS09270	COG0494	nUDIX hydrolase
YEY1_RS09275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YEY1_RS09285	COG1335	isochorismatase
YEY1_RS09290	COG1801	Protein of unknown function DUF72
YEY1_RS09295	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YEY1_RS09300	COG2226	methyltransferase
YEY1_RS09305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YEY1_RS09320	COG1349	DNA-binding transcription factor activity
YEY1_RS09330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS09340	COG3716	PTS system mannose fructose sorbose family IID component
YEY1_RS09345	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS09350	COG2222	sugar isomerase
YEY1_RS09360	COG4942	peptidase
YEY1_RS09385	COG3443	Belongs to the bacterial solute-binding protein 9 family
YEY1_RS09395	COG0402	S-adenosylhomocysteine deaminase activity
YEY1_RS09405	COG1228	amidohydrolase
YEY1_RS09435	COG2988	succinylglutamate desuccinylase activity
YEY1_RS09440	COG3724	N-succinylarginine dihydrolase activity
YEY1_RS09450	COG3138	arginine N-succinyltransferase
YEY1_RS09455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YEY1_RS09460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_RS09465	COG1271	oxidase subunit
YEY1_RS09470	COG1294	oxidase, subunit
YEY1_RS09480	COG3850	Histidine kinase
YEY1_RS09485	COG0583	DNA-binding transcription factor activity
YEY1_RS09500	COG2814	Major facilitator Superfamily
YEY1_RS09510	COG0387	Pfam Sodium calcium exchanger
YEY1_RS09515	COG0728	peptidoglycan biosynthetic process
YEY1_RS09520	COG0673	inositol 2-dehydrogenase activity
YEY1_RS09530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YEY1_RS09545	COG0477	Major facilitator Superfamily
YEY1_RS09555	COG3381	protein complex oligomerization
YEY1_RS09560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YEY1_RS09565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YEY1_RS09585	COG3706	GGDEF domain
YEY1_RS09590	COG0659	secondary active sulfate transmembrane transporter activity
YEY1_RS09595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YEY1_RS09610	COG2890	protein-(glutamine-N5) methyltransferase activity
YEY1_RS09615	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YEY1_RS09620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YEY1_RS09625	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
YEY1_RS09635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YEY1_RS09650	COG0193	aminoacyl-tRNA hydrolase activity
YEY1_RS09660	COG0012	GTP binding
YEY1_RS09675	COG2979	Protein of unknown function (DUF533)
YEY1_RS09680	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YEY1_RS09685	COG3772	lysozyme
YEY1_RS09825	COG3041	Addiction module toxin RelE StbE family
YEY1_RS09830	COG3077	Addiction module antitoxin, RelB DinJ family
YEY1_RS09870	COG3328	transposase activity
YEY1_RS09900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YEY1_RS09905	COG0322	excinuclease ABC activity
YEY1_RS09910	COG2197	response regulator
YEY1_RS09920	COG3136	membrane protein required for alginate biosynthesis
YEY1_RS09930	COG0366	Alpha amylase catalytic
YEY1_RS09945	COG2226	methyltransferase
YEY1_RS09955	COG0582	viral genome integration into host DNA
YEY1_RS09965	COG1113	amino acid transport
YEY1_RS09970	COG1309	transcriptional regulator
YEY1_RS09980	COG1335	isochorismatase
YEY1_RS09985	COG0251	oxidation-reduction process
YEY1_RS09990	COG2267	carboxylic ester hydrolase activity
YEY1_RS09995	COG0778	Nitroreductase
YEY1_RS10000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YEY1_RS10015	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
YEY1_RS10025	COG0655	NAD(P)H dehydrogenase (quinone) activity
YEY1_RS10035	COG2822	iron ion transport
YEY1_RS10040	COG0672	)-iron permease
YEY1_RS10050	COG3157	Type VI secretion system effector, Hcp
YEY1_RS10070	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YEY1_RS10070	COG0506	proline dehydrogenase activity
YEY1_RS10070	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YEY1_RS10085	COG1126	abc transporter atp-binding protein
YEY1_RS10090	COG0765	amino acid transport
YEY1_RS10095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS10100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YEY1_RS10110	COG1191	sigma factor activity
YEY1_RS10145	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YEY1_RS10150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YEY1_RS10180	COG0582	viral genome integration into host DNA
YEY1_RS10185	COG1677	Flagellar hook-basal body complex protein FliE
YEY1_RS10200	COG1317	bacterial-type flagellum organization
YEY1_RS10220	COG1580	Controls the rotational direction of flagella during chemotaxis
YEY1_RS10240	COG1338	Plays a role in the flagellum-specific transport system
YEY1_RS10260	COG1256	bacterial-type flagellum assembly
YEY1_RS10295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YEY1_RS10300	COG1558	bacterial-type flagellum-dependent cell motility
YEY1_RS10305	COG1815	bacterial-type flagellum-dependent cell motility
YEY1_RS10315	COG2747	anti-sigma28 factor FlgM
YEY1_RS10320	COG3418	PFAM FlgN family protein
YEY1_RS10340	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YEY1_RS10345	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YEY1_RS10350	COG1404	Belongs to the peptidase S8 family
YEY1_RS10350	COG4935	Belongs to the peptidase S8 family
YEY1_RS10355	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YEY1_RS10360	COG0745	RESPONSE REGULATOR receiver
YEY1_RS10370	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YEY1_RS10375	COG0840	transmembrane signaling receptor activity
YEY1_RS10380	COG0840	transmembrane signaling receptor activity
YEY1_RS10390	COG0835	chemotaxis
YEY1_RS10395	COG2198	Histidine kinase
YEY1_RS10395	COG0643	Histidine kinase
YEY1_RS10400	COG1360	Flagellar Motor Protein
YEY1_RS10420	COG0589	response to stress
YEY1_RS10425	COG2130	NADP-dependent
YEY1_RS10435	COG1285	pathogenesis
YEY1_RS10450	COG0840	transmembrane signaling receptor activity
YEY1_RS10465	COG1609	Transcriptional regulator
YEY1_RS10470	COG3250	beta-galactosidase activity
YEY1_RS10475	COG0604	alcohol dehydrogenase
YEY1_RS10475	COG3321	synthase
YEY1_RS10475	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS10505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
YEY1_RS10515	COG3263	regulation of cellular component size
YEY1_RS10525	COG3916	Acyl-homoserine-lactone synthase
YEY1_RS10530	COG2771	luxR family
YEY1_RS10535	COG4235	cytochrome complex assembly
YEY1_RS10540	COG3088	subunit of a heme lyase
YEY1_RS10545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YEY1_RS10550	COG1138	Cytochrome C-type biogenesis protein
YEY1_RS10555	COG3301	Polysulphide reductase, NrfD
YEY1_RS10560	COG0437	4 iron, 4 sulfur cluster binding
YEY1_RS10565	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
YEY1_RS10585	COG2920	part of a sulfur-relay system
YEY1_RS10590	COG1254	Belongs to the acylphosphatase family
YEY1_RS10605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YEY1_RS10610	COG3785	DNA binding
YEY1_RS10615	COG1832	CoA-binding protein
YEY1_RS10625	COG1803	Methylglyoxal synthase
YEY1_RS10630	COG0210	DNA helicase
YEY1_RS10635	COG3304	Inner membrane component domain
YEY1_RS10640	COG1289	transmembrane transporter activity
YEY1_RS10645	COG3070	regulator of competence-specific genes
YEY1_RS10650	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
YEY1_RS10660	COG3120	sequence-specific DNA binding
YEY1_RS10665	COG1067	ATP-dependent peptidase activity
YEY1_RS10670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YEY1_RS10680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YEY1_RS10685	COG3130	regulation of translation
YEY1_RS10690	COG3009	Protein conserved in bacteria
YEY1_RS10695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YEY1_RS10695	COG3008	intermembrane lipid transfer
YEY1_RS10700	COG2995	paraquat-inducible protein a
YEY1_RS10705	COG0488	(ABC) transporter
YEY1_RS10710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
YEY1_RS10710	COG0116	Belongs to the methyltransferase superfamily
YEY1_RS10715	COG0633	Ferredoxin
YEY1_RS10715	COG3217	Mosc domain protein beta barrel domain protein
YEY1_RS10725	COG0167	dihydroorotate dehydrogenase activity
YEY1_RS10730	COG0308	aminopeptidase N
YEY1_RS10740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YEY1_RS10745	COG0017	Asparaginyl-tRNA synthetase
YEY1_RS10755	COG1448	Aminotransferase
YEY1_RS10760	COG2200	EAL domain
YEY1_RS10765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YEY1_RS10770	COG3108	Peptidase M15
YEY1_RS10775	COG2989	Protein conserved in bacteria
YEY1_RS10780	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
YEY1_RS10790	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YEY1_RS10795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YEY1_RS10800	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YEY1_RS10805	COG3173	Aminoglycoside phosphotransferase
YEY1_RS10810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YEY1_RS10815	COG2835	tetraacyldisaccharide 4'-kinase activity
YEY1_RS10820	COG1278	Cold shock
YEY1_RS10835	COG5383	Protein conserved in bacteria
YEY1_RS10840	COG1663	tetraacyldisaccharide 4'-kinase activity
YEY1_RS10850	COG2333	competence protein COMEC
YEY1_RS10850	COG0658	competence protein
YEY1_RS10855	COG0776	regulation of translation
YEY1_RS10860	COG0539	negative regulation of cytoplasmic translation
YEY1_RS10865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YEY1_RS10870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YEY1_RS10875	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YEY1_RS10880	COG2323	membrane
YEY1_RS10885	COG0252	asparaginase activity
YEY1_RS10890	COG1944	ATP diphosphatase activity
YEY1_RS10905	COG2116	formate transmembrane transporter activity
YEY1_RS10910	COG1882	Formate acetyltransferase
YEY1_RS10915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YEY1_RS10920	COG2814	Major facilitator Superfamily
YEY1_RS10925	COG3328	transposase activity
YEY1_RS10935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YEY1_RS10940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YEY1_RS10945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YEY1_RS10950	COG3107	peptidoglycan biosynthetic process
YEY1_RS10950	COG1674	ftsk spoiiie
YEY1_RS10955	COG1522	sequence-specific DNA binding
YEY1_RS10960	COG0492	ferredoxin-NADP+ reductase activity
YEY1_RS10970	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YEY1_RS10975	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YEY1_RS10980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YEY1_RS10985	COG0542	response to heat
YEY1_RS10990	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YEY1_RS10995	COG1278	Cold shock
YEY1_RS11005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS11010	COG2990	Protein conserved in bacteria
YEY1_RS11015	COG3593	DNA synthesis involved in DNA repair
YEY1_RS11020	COG2431	L-lysine efflux transmembrane transporter activity
YEY1_RS11025	COG1151	hydroxylamine reductase activity
YEY1_RS11030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YEY1_RS11035	COG0028	Belongs to the TPP enzyme family
YEY1_RS11045	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YEY1_RS11050	COG0702	epimerase
YEY1_RS11055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_RS11065	COG1126	abc transporter atp-binding protein
YEY1_RS11070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS11075	COG4215	(ABC) transporter
YEY1_RS11080	COG4160	amino acid transport
YEY1_RS11085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS11090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YEY1_RS11100	COG1177	transmembrane transport
YEY1_RS11105	COG1176	ABC-type spermidine putrescine transport system, permease component I
YEY1_RS11110	COG3842	ATPase activity
YEY1_RS11115	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YEY1_RS11135	COG2985	domain, Protein
YEY1_RS11135	COG0569	domain protein
YEY1_RS11145	COG0671	phosphoesterase, PA-phosphatase related
YEY1_RS11150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YEY1_RS11155	COG1349	DNA-binding transcription factor activity
YEY1_RS11160	COG0814	amino acid
YEY1_RS11165	COG1760	l-serine dehydratase
YEY1_RS11180	COG1686	Belongs to the peptidase S11 family
YEY1_RS11190	COG0626	cystathionine gamma-synthase activity
YEY1_RS11195	COG2011	ABC-type metal ion transport system permease component
YEY1_RS11220	COG0625	glutathione transferase activity
YEY1_RS11225	COG4771	TonB-dependent receptor
YEY1_RS11235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YEY1_RS11240	COG0833	amino acid
YEY1_RS11245	COG0583	DNA-binding transcription factor activity
YEY1_RS11260	COG2855	membrane
YEY1_RS11270	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
YEY1_RS11295	COG3710	Transcriptional regulator
YEY1_RS11300	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YEY1_RS11300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YEY1_RS11300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YEY1_RS11305	COG1105	Belongs to the carbohydrate kinase PfkB family
YEY1_RS11320	COG3005	denitrification pathway
YEY1_RS11325	COG0243	molybdopterin cofactor binding
YEY1_RS11340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YEY1_RS11345	COG1312	Catalyzes the dehydration of D-mannonate
YEY1_RS11355	COG0246	Mannitol dehydrogenase
YEY1_RS11360	COG2186	Transcriptional regulator
YEY1_RS11370	COG0523	cobalamin synthesis protein
YEY1_RS11375	COG0671	phosphoesterase, PA-phosphatase related
YEY1_RS11380	COG0791	NLP P60 protein
YEY1_RS11390	COG2200	EAL domain
YEY1_RS11395	COG4166	transmembrane transport
YEY1_RS11400	COG4174	ABC transporter (Permease)
YEY1_RS11405	COG4239	(ABC) transporter, permease
YEY1_RS11410	COG4172	Belongs to the ABC transporter superfamily
YEY1_RS11420	COG2814	Major facilitator Superfamily
YEY1_RS11425	COG1187	pseudouridine synthase activity
YEY1_RS11430	COG1061	Type III restriction enzyme res subunit
YEY1_RS11435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YEY1_RS11440	COG3081	Nucleoid-associated protein
YEY1_RS11445	COG3082	Protein of unknown function (DUF1414)
YEY1_RS11470	COG3328	transposase activity
YEY1_RS11480	COG2723	6-phospho-beta-galactosidase activity
YEY1_RS11485	COG1263	PTS System
YEY1_RS11485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS11485	COG2190	(PTS) system
YEY1_RS11490	COG1737	Transcriptional regulator
YEY1_RS11535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YEY1_RS11550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YEY1_RS11560	COG2223	nitrite transmembrane transporter activity
YEY1_RS11565	COG0642	Histidine kinase
YEY1_RS11565	COG2198	Histidine kinase
YEY1_RS11570	COG2197	response regulator
YEY1_RS11575	COG0784	Response regulator, receiver
YEY1_RS11575	COG2205	protein histidine kinase activity
YEY1_RS11585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YEY1_RS11590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YEY1_RS11600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YEY1_RS11605	COG4574	serine-type endopeptidase inhibitor activity
YEY1_RS11635	COG0814	amino acid
YEY1_RS11655	COG1441	menaquinone biosynthetic process
YEY1_RS11660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YEY1_RS11665	COG0596	Alpha beta hydrolase
YEY1_RS11670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YEY1_RS11675	COG1169	isochorismate synthase
YEY1_RS11680	COG4575	ribosome binding
YEY1_RS11685	COG0129	dihydroxy-acid dehydratase activity
YEY1_RS11690	COG4702	Belongs to the UPF0303 family
YEY1_RS11700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YEY1_RS11705	COG1609	Transcriptional regulator
YEY1_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS11715	COG3265	gluconokinase activity
YEY1_RS11735	COG1007	ATP synthesis coupled electron transport
YEY1_RS11740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS11745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YEY1_RS11750	COG0713	ATP synthesis coupled electron transport
YEY1_RS11755	COG0839	Belongs to the complex I subunit 6 family
YEY1_RS11760	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS11765	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YEY1_RS11770	COG1034	ATP synthesis coupled electron transport
YEY1_RS11785	COG0649	NAD binding
YEY1_RS11785	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS11790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS11795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS11800	COG0583	DNA-binding transcription factor activity
YEY1_RS11805	COG0436	Aminotransferase
YEY1_RS11815	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
YEY1_RS11820	COG0471	metal ion transport
YEY1_RS11820	COG0490	domain, Protein
YEY1_RS11830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_RS11835	COG3013	Belongs to the UPF0304 family
YEY1_RS11840	COG3092	negative regulation of chromosome organization
YEY1_RS11850	COG0857	belongs to the CobB CobQ family
YEY1_RS11850	COG0280	phosphate acetyltransferase
YEY1_RS11855	COG1609	Transcriptional regulator
YEY1_RS11860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS11870	COG3037	sugar-specific permease SgaT UlaA
YEY1_RS11885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YEY1_RS11890	COG0622	Phosphoesterase
YEY1_RS11900	COG1090	epimerase
YEY1_RS11915	COG4598	ABC transporter
YEY1_RS11920	COG4160	amino acid transport
YEY1_RS11925	COG4215	(ABC) transporter
YEY1_RS11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS11935	COG0163	prenyltransferase activity
YEY1_RS11940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YEY1_RS11945	COG1286	toxin biosynthetic process
YEY1_RS11950	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YEY1_RS11955	COG0285	dihydrofolate synthase activity
YEY1_RS11960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YEY1_RS11965	COG0586	Pfam SNARE associated Golgi protein
YEY1_RS11975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YEY1_RS11980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YEY1_RS11990	COG0697	spore germination
YEY1_RS11995	COG0697	spore germination
YEY1_RS12000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_RS12005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YEY1_RS12030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YEY1_RS12040	COG1609	Transcriptional regulator
YEY1_RS12050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YEY1_RS12055	COG2723	6-phospho-beta-galactosidase activity
YEY1_RS12060	COG1447	Phosphotransferase system cellobiose-specific component IIA
YEY1_RS12070	COG1794	racemase activity, acting on amino acids and derivatives
YEY1_RS12080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YEY1_RS12085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YEY1_RS12085	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YEY1_RS12095	COG3101	peptidyl-lysine hydroxylation
YEY1_RS12105	COG0730	response to heat
YEY1_RS12110	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
YEY1_RS12115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YEY1_RS12120	COG2890	protein-(glutamine-N5) methyltransferase activity
YEY1_RS12125	COG2840	Smr protein MutS2
YEY1_RS12130	COG2062	phosphohistidine phosphatase, SixA
YEY1_RS12140	COG1250	3-hydroxyacyl-CoA dehydrogenase
YEY1_RS12140	COG1024	Enoyl-CoA hydratase
YEY1_RS12145	COG0183	Belongs to the thiolase family
YEY1_RS12150	COG3691	Protein conserved in bacteria
YEY1_RS12165	COG3088	subunit of a heme lyase
YEY1_RS12165	COG4235	cytochrome complex assembly
YEY1_RS12175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YEY1_RS12180	COG1138	Cytochrome C-type biogenesis protein
YEY1_RS12185	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
YEY1_RS12190	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YEY1_RS12195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YEY1_RS12200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YEY1_RS12210	COG2116	formate transmembrane transporter activity
YEY1_RS12230	COG2824	Alkylphosphonate utilization operon protein PhnA
YEY1_RS12235	COG1695	Transcriptional regulator
YEY1_RS12245	COG2723	6-phospho-beta-galactosidase activity
YEY1_RS12250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS12250	COG1263	PTS System
YEY1_RS12255	COG1609	Transcriptional regulator
YEY1_RS12260	COG2353	YceI-like domain
YEY1_RS12270	COG0657	acetylesterase activity
YEY1_RS12270	COG2755	lipolytic protein G-D-S-L family
YEY1_RS12290	COG1127	ABC transporter
YEY1_RS12295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YEY1_RS12315	COG0531	amino acid
YEY1_RS12320	COG2951	lytic endotransglycosylase activity
YEY1_RS12340	COG1280	lysine exporter protein (LysE YggA)
YEY1_RS12350	COG1598	PFAM Uncharacterised protein family UPF0150
YEY1_RS12360	COG3038	cytochrome b561
YEY1_RS12365	COG0436	Aminotransferase
YEY1_RS12380	COG3275	phosphorelay sensor kinase activity
YEY1_RS12385	COG3279	Response regulator of the LytR AlgR family
YEY1_RS12390	COG2223	nitrite transmembrane transporter activity
YEY1_RS12400	COG0837	glucose binding
YEY1_RS12415	COG3961	Belongs to the TPP enzyme family
YEY1_RS12420	COG0667	Aldo Keto reductase
YEY1_RS12430	COG1914	H( )-stimulated, divalent metal cation uptake system
YEY1_RS12435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YEY1_RS12460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YEY1_RS12490	COG3530	Putative quorum-sensing-regulated virulence factor
YEY1_RS12495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YEY1_RS12515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS12520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YEY1_RS12530	COG2205	protein histidine kinase activity
YEY1_RS12535	COG0745	RESPONSE REGULATOR receiver
YEY1_RS12540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS12560	COG4208	sulfate ABC transporter
YEY1_RS12565	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YEY1_RS12570	COG4150	thiosulfate binding
YEY1_RS12585	COG1737	Transcriptional regulator
YEY1_RS12590	COG2731	YhcH YjgK YiaL family protein
YEY1_RS12605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YEY1_RS12620	COG2837	iron assimilation
YEY1_RS12630	COG3111	PFAM Bacterial OB fold (BOF) protein
YEY1_RS12635	COG0456	acetyltransferase
YEY1_RS12640	COG0408	coproporphyrinogen oxidase activity
YEY1_RS12645	COG1671	Belongs to the UPF0178 family
YEY1_RS12665	COG2943	transferase activity, transferring hexosyl groups
YEY1_RS12670	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YEY1_RS12690	COG3121	Chaperone
YEY1_RS12715	COG1070	Carbohydrate kinase
YEY1_RS12720	COG1070	Carbohydrate kinase
YEY1_RS12730	COG3228	Belongs to the MtfA family
YEY1_RS12740	COG0582	viral genome integration into host DNA
YEY1_RS12745	COG0583	DNA-binding transcription factor activity
YEY1_RS12750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YEY1_RS12775	COG2003	Belongs to the UPF0758 family
YEY1_RS12825	COG2205	protein histidine kinase activity
YEY1_RS12825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS12850	COG3121	Chaperone
YEY1_RS12870	COG3122	Protein conserved in bacteria
YEY1_RS12875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS12875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS12880	COG2814	Major facilitator Superfamily
YEY1_RS12895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YEY1_RS12910	COG0471	metal ion transport
YEY1_RS12920	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
YEY1_RS12920	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
YEY1_RS12925	COG3051	citrate lyase alpha subunit
YEY1_RS12930	COG2301	Belongs to the HpcH HpaI aldolase family
YEY1_RS12935	COG3052	prosthetic group binding
YEY1_RS12940	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
YEY1_RS12945	COG3290	protein histidine kinase activity
YEY1_RS12950	COG4565	transcriptional regulatory protein
YEY1_RS12965	COG2271	Major facilitator Superfamily
YEY1_RS12970	COG1840	ABC-type Fe3 transport system, periplasmic component
YEY1_RS12980	COG3842	ATPase activity
YEY1_RS13015	COG0835	chemotaxis
YEY1_RS13015	COG0784	Response regulator, receiver
YEY1_RS13025	COG1349	DNA-binding transcription factor activity
YEY1_RS13030	COG0561	phosphatase activity
YEY1_RS13035	COG0352	thiamine-phosphate diphosphorylase activity
YEY1_RS13045	COG0534	Mate efflux family protein
YEY1_RS13050	COG0137	argininosuccinate synthase activity
YEY1_RS13120	COG3188	usher protein
YEY1_RS13125	COG3121	Chaperone
YEY1_RS13190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YEY1_RS13210	COG1492	cobalamin metabolic process
YEY1_RS13275	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
YEY1_RS13285	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YEY1_RS13360	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
YEY1_RS13370	COG1012	belongs to the aldehyde dehydrogenase family
YEY1_RS13380	COG4656	Part of a membrane complex involved in electron transport
YEY1_RS13400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YEY1_RS13410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YEY1_RS13430	COG1129	ABC transporter
YEY1_RS13435	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS13445	COG2926	Belongs to the UPF0265 family
YEY1_RS13450	COG1289	transmembrane transporter activity
YEY1_RS13455	COG1022	Amp-dependent synthetase and ligase
YEY1_RS13455	COG3320	Male sterility
YEY1_RS13460	COG2925	Exonuclease
YEY1_RS13465	COG0531	amino acid
YEY1_RS13475	COG0371	Dehydrogenase
YEY1_RS13485	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS13490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_RS13500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YEY1_RS13510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YEY1_RS13515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YEY1_RS13515	COG0131	Imidazoleglycerol-phosphate dehydratase
YEY1_RS13525	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YEY1_RS13530	COG0107	imidazoleglycerol-phosphate synthase activity
YEY1_RS13535	COG0140	phosphoribosyl-ATP diphosphatase activity
YEY1_RS13535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YEY1_RS13540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YEY1_RS13550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YEY1_RS13555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YEY1_RS13570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YEY1_RS13570	COG0473	3-isopropylmalate dehydrogenase activity
YEY1_RS13595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_RS13640	COG1253	flavin adenine dinucleotide binding
YEY1_RS13645	COG3069	C4-dicarboxylate transmembrane transporter activity
YEY1_RS13650	COG2982	Protein involved in outer membrane biogenesis
YEY1_RS13660	COG0572	uridine kinase
YEY1_RS13665	COG0489	protein tyrosine kinase activity
YEY1_RS13670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YEY1_RS13670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YEY1_RS13690	COG2814	Major facilitator Superfamily
YEY1_RS13695	COG1380	Effector of murein hydrolase LrgA
YEY1_RS13700	COG1346	cytolysis
YEY1_RS13715	COG0281	malic enzyme
YEY1_RS13720	COG2949	membrane
YEY1_RS13725	COG0298	carbon dioxide binding
YEY1_RS13730	COG0375	protein maturation
YEY1_RS13735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YEY1_RS13740	COG0651	ATP synthesis coupled electron transport
YEY1_RS13745	COG0650	Formate hydrogenlyase subunit 4
YEY1_RS13750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YEY1_RS13755	COG4237	Hydrogenase 4 membrane
YEY1_RS13760	COG0651	ATP synthesis coupled electron transport
YEY1_RS13765	COG3261	NADH dehydrogenase
YEY1_RS13765	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
YEY1_RS13770	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YEY1_RS13775	COG3260	NADH ubiquinone oxidoreductase 20
YEY1_RS13785	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YEY1_RS13790	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YEY1_RS13795	COG3383	formate dehydrogenase (NAD+) activity
YEY1_RS13800	COG3604	Transcriptional regulator
YEY1_RS13825	COG2311	Membrane
YEY1_RS13830	COG0302	gtp cyclohydrolase
YEY1_RS13835	COG0477	Major facilitator Superfamily
YEY1_RS13840	COG0583	DNA-binding transcription factor activity
YEY1_RS13870	COG1136	(ABC) transporter
YEY1_RS13870	COG0577	efflux transmembrane transporter activity
YEY1_RS13885	COG0303	'Molybdopterin
YEY1_RS13890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YEY1_RS13900	COG0488	(ABC) transporter
YEY1_RS13920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YEY1_RS13940	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
YEY1_RS13955	COG4106	trans-aconitate 2-methyltransferase activity
YEY1_RS13960	COG0783	Belongs to the Dps family
YEY1_RS13965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YEY1_RS13970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS13975	COG0765	amino acid transport
YEY1_RS13980	COG1126	abc transporter atp-binding protein
YEY1_RS13990	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
YEY1_RS14015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YEY1_RS14020	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YEY1_RS14040	COG0697	spore germination
YEY1_RS14055	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS14065	COG1174	glycine betaine transport
YEY1_RS14070	COG1125	glycine betaine transport
YEY1_RS14075	COG1174	glycine betaine transport
YEY1_RS14080	COG1732	Glycine betaine
YEY1_RS14095	COG2897	thiosulfate sulfurtransferase activity
YEY1_RS14105	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YEY1_RS14125	COG4807	Protein conserved in bacteria
YEY1_RS14140	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YEY1_RS14150	COG2261	transglycosylase associated protein
YEY1_RS14170	COG0277	FAD linked oxidase domain protein
YEY1_RS14175	COG1686	Belongs to the peptidase S11 family
YEY1_RS14185	COG2239	Acts as a magnesium transporter
YEY1_RS14195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YEY1_RS14200	COG0513	Belongs to the DEAD box helicase family
YEY1_RS14205	COG1309	transcriptional regulator
YEY1_RS14210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS14215	COG1131	(ABC) transporter
YEY1_RS14220	COG0842	Transport permease protein
YEY1_RS14225	COG0842	Transport permease protein
YEY1_RS14230	COG0670	Belongs to the BI1 family
YEY1_RS14235	COG0314	molybdopterin synthase activity
YEY1_RS14240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YEY1_RS14245	COG0315	cyclic pyranopterin monophosphate synthase activity
YEY1_RS14250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YEY1_RS14255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YEY1_RS14260	COG4628	conserved protein (DUF2132)
YEY1_RS14265	COG0556	nucleotide-excision repair
YEY1_RS14280	COG2226	methyltransferase
YEY1_RS14285	COG0156	8-amino-7-oxononanoate synthase activity
YEY1_RS14290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YEY1_RS14300	COG2706	6-phosphogluconolactonase activity
YEY1_RS14305	COG0561	phosphatase activity
YEY1_RS14315	COG4149	molybdate abc transporter
YEY1_RS14320	COG0725	ABC transporter, periplasmic molybdate-binding protein
YEY1_RS14330	COG3585	molybdate ion transport
YEY1_RS14330	COG2005	Transcriptional regulator
YEY1_RS14335	COG1119	ATPase activity
YEY1_RS14345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YEY1_RS14350	COG1085	galactose-1-phosphate uridylyltransferase
YEY1_RS14355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
YEY1_RS14360	COG2017	converts alpha-aldose to the beta-anomer
YEY1_RS14385	COG0588	phosphoglycerate mutase activity
YEY1_RS14390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YEY1_RS14395	COG1230	cation diffusion facilitator family transporter
YEY1_RS14405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YEY1_RS14440	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YEY1_RS14445	COG2885	chlorophyll binding
YEY1_RS14450	COG0823	Involved in the tonB-independent uptake of proteins
YEY1_RS14455	COG3064	Membrane
YEY1_RS14455	COG3064	Membrane
YEY1_RS14460	COG0848	biopolymer transport protein
YEY1_RS14465	COG0811	peptide transport
YEY1_RS14470	COG0824	Thioesterase
YEY1_RS14475	COG3790	cyd operon protein YbgE
YEY1_RS14480	COG4890	Cyd operon protein YbgT
YEY1_RS14485	COG1294	oxidase, subunit
YEY1_RS14490	COG1271	oxidase subunit
YEY1_RS14495	COG0737	Belongs to the 5'-nucleotidase family
YEY1_RS14500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YEY1_RS14505	COG0045	succinate-CoA ligase (ADP-forming) activity
YEY1_RS14510	COG0508	dehydrogenase complex catalyzes the overall conversion of
YEY1_RS14515	COG0567	Dehydrogenase, E1 component
YEY1_RS14525	COG1053	succinate dehydrogenase
YEY1_RS14530	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YEY1_RS14535	COG2009	succinate dehydrogenase
YEY1_RS14550	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YEY1_RS14565	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YEY1_RS14570	COG1984	allophanate hydrolase subunit 2
YEY1_RS14580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YEY1_RS14585	COG5212	phosphodiesterase
YEY1_RS14595	COG3272	Protein of unknown function (DUF1722)
YEY1_RS14600	COG1073	alpha beta
YEY1_RS14600	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YEY1_RS14600	COG3064	Membrane
YEY1_RS14600	COG1073	alpha beta
YEY1_RS14600	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YEY1_RS14600	COG3064	Membrane
YEY1_RS14605	COG2994	toxin metabolic process
YEY1_RS14630	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YEY1_RS14635	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YEY1_RS14640	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YEY1_RS14645	COG2205	protein histidine kinase activity
YEY1_RS14650	COG0745	RESPONSE REGULATOR receiver
YEY1_RS14665	COG0033	Phosphoglucomutase
YEY1_RS14670	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YEY1_RS14675	COG0596	Alpha beta hydrolase
YEY1_RS14685	COG0840	transmembrane signaling receptor activity
YEY1_RS14695	COG0735	belongs to the Fur family
YEY1_RS14715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YEY1_RS14720	COG1263	PTS System
YEY1_RS14720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS14720	COG2190	(PTS) system
YEY1_RS14725	COG0363	glucosamine-6-phosphate deaminase activity
YEY1_RS14730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YEY1_RS14735	COG1846	Transcriptional regulator
YEY1_RS14735	COG1940	carbohydrate kinase activity
YEY1_RS14740	COG0647	UMP catabolic process
YEY1_RS14745	COG0367	asparagine synthase
YEY1_RS14780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YEY1_RS14785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YEY1_RS14790	COG1702	phosphate starvation-inducible protein PhoH
YEY1_RS14795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YEY1_RS14800	COG4535	Mg2 and Co2 transporter CorC
YEY1_RS14805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YEY1_RS14820	COG0765	amino acid transport
YEY1_RS14825	COG0765	amino acid transport
YEY1_RS14830	COG1126	abc transporter atp-binding protein
YEY1_RS14835	COG2888	peptidyl-tyrosine sulfation
YEY1_RS14840	COG0495	leucyl-tRNA aminoacylation
YEY1_RS14845	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
YEY1_RS14850	COG1466	dna polymerase III delta subunit
YEY1_RS14855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YEY1_RS14860	COG0799	negative regulation of ribosome biogenesis
YEY1_RS14870	COG0768	penicillin binding
YEY1_RS14875	COG0772	Belongs to the SEDS family
YEY1_RS14880	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YEY1_RS14885	COG1686	Belongs to the peptidase S11 family
YEY1_RS14890	COG2921	Belongs to the UPF0250 family
YEY1_RS14895	COG0321	lipoyl(octanoyl) transferase activity
YEY1_RS14900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YEY1_RS14905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YEY1_RS14910	COG3706	GGDEF domain
YEY1_RS14925	COG1278	Cold shock
YEY1_RS14930	COG2197	response regulator
YEY1_RS14940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YEY1_RS14955	COG5265	(ABC) transporter
YEY1_RS14965	COG2986	histidine ammonia-lyase
YEY1_RS14970	COG2850	peptidyl-arginine hydroxylation
YEY1_RS14985	COG0582	viral genome integration into host DNA
YEY1_RS15060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YEY1_RS15065	COG2501	S4 domain
YEY1_RS15070	COG0215	cysteine-tRNA ligase activity
YEY1_RS15075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YEY1_RS15080	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YEY1_RS15085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YEY1_RS15090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YEY1_RS15095	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YEY1_RS15100	COG4181	ATPase activity
YEY1_RS15105	COG2755	lipolytic protein G-D-S-L family
YEY1_RS15110	COG0300	oxidoreductase activity
YEY1_RS15115	COG3118	belongs to the thioredoxin family
YEY1_RS15120	COG0330	HflC and HflK could
YEY1_RS15125	COG1585	Membrane protein implicated in regulation of membrane protease activity
YEY1_RS15130	COG0789	Transcriptional regulator
YEY1_RS15135	COG2217	Heavy metal translocating P-type atpase
YEY1_RS15140	COG3735	TraB family
YEY1_RS15145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YEY1_RS15155	COG0737	Belongs to the 5'-nucleotidase family
YEY1_RS15160	COG2223	nitrite transmembrane transporter activity
YEY1_RS15165	COG4651	solute:proton antiporter activity
YEY1_RS15165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YEY1_RS15170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_RS15190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YEY1_RS15195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YEY1_RS15200	COG0438	transferase activity, transferring glycosyl groups
YEY1_RS15205	COG1215	transferase activity, transferring glycosyl groups
YEY1_RS15210	COG1442	glycosyl transferase family 8
YEY1_RS15210	COG1216	Glycosyl transferase, family 2
YEY1_RS15215	COG2244	polysaccharide biosynthetic process
YEY1_RS15220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YEY1_RS15225	COG0563	adenylate kinase activity
YEY1_RS15230	COG0326	Molecular chaperone. Has ATPase activity
YEY1_RS15235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YEY1_RS15240	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YEY1_RS15250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YEY1_RS15255	COG2832	Protein of unknown function (DUF454)
YEY1_RS15270	COG3264	Mechanosensitive ion channel
YEY1_RS15270	COG1196	nuclear chromosome segregation
YEY1_RS15275	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YEY1_RS15280	COG1309	transcriptional regulator
YEY1_RS15285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS15290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YEY1_RS15310	COG3457	Alanine racemase
YEY1_RS15315	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
YEY1_RS15330	COG0254	rRNA binding
YEY1_RS15335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YEY1_RS15340	COG0803	Belongs to the bacterial solute-binding protein 9 family
YEY1_RS15345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YEY1_RS15380	COG3695	enzyme binding
YEY1_RS15385	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YEY1_RS15390	COG1946	Acyl-CoA thioesterase
YEY1_RS15395	COG0004	ammonium transporteR
YEY1_RS15400	COG0347	Belongs to the P(II) protein family
YEY1_RS15405	COG1132	(ABC) transporter
YEY1_RS15410	COG1132	(ABC) transporter
YEY1_RS15415	COG1522	sequence-specific DNA binding
YEY1_RS15425	COG0561	phosphatase activity
YEY1_RS15430	COG4533	DNA binding
YEY1_RS15435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YEY1_RS15440	COG0824	Thioesterase
YEY1_RS15445	COG1555	photosystem II stabilization
YEY1_RS15450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YEY1_RS15455	COG0776	regulation of translation
YEY1_RS15460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YEY1_RS15465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YEY1_RS15470	COG0740	serine-type endopeptidase activity
YEY1_RS15475	COG0544	peptidyl-prolyl cis-trans isomerase activity
YEY1_RS15485	COG0271	Belongs to the BolA IbaG family
YEY1_RS15490	COG3056	Lipoprotein
YEY1_RS15495	COG2223	nitrite transmembrane transporter activity
YEY1_RS15505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YEY1_RS15510	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YEY1_RS15515	COG1845	cytochrome c oxidase, subunit III
YEY1_RS15520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YEY1_RS15525	COG0109	protoheme IX farnesyltransferase activity
YEY1_RS15530	COG2814	Major facilitator Superfamily
YEY1_RS15535	COG1666	GTP binding
YEY1_RS15540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YEY1_RS15550	COG0301	tRNA thio-modification
YEY1_RS15550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YEY1_RS15560	COG0142	geranyltranstransferase activity
YEY1_RS15565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YEY1_RS15575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YEY1_RS15580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YEY1_RS15585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YEY1_RS15590	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YEY1_RS15595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YEY1_RS15595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YEY1_RS15600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YEY1_RS15625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YEY1_RS15630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YEY1_RS15635	COG1862	Preprotein translocase
YEY1_RS15640	COG0343	queuine tRNA-ribosyltransferase activity
YEY1_RS15655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YEY1_RS15660	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YEY1_RS15665	COG0450	alkyl hydroperoxide reductase
YEY1_RS15685	COG0366	Alpha amylase catalytic
YEY1_RS15705	COG5002	protein histidine kinase activity
YEY1_RS15710	COG0745	RESPONSE REGULATOR receiver
YEY1_RS15715	COG0420	3'-5' exonuclease activity
YEY1_RS15720	COG0419	ATPase involved in DNA repair
YEY1_RS15725	COG1940	carbohydrate kinase activity
YEY1_RS15730	COG2974	May be involved in recombination
YEY1_RS15735	COG3123	guanosine phosphorylase activity
YEY1_RS15740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YEY1_RS15765	COG2226	methyltransferase
YEY1_RS15780	COG3459	Glycosyltransferase 36 associated
YEY1_RS15800	COG2188	Transcriptional regulator
YEY1_RS15805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YEY1_RS15810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YEY1_RS15820	COG1073	alpha beta
YEY1_RS15825	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YEY1_RS15830	COG2195	Cleaves the N-terminal amino acid of tripeptides
YEY1_RS15835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YEY1_RS15850	COG2964	Protein conserved in bacteria
YEY1_RS15855	COG1181	Belongs to the D-alanine--D-alanine ligase family
YEY1_RS15870	COG2991	Protein conserved in bacteria
YEY1_RS15875	COG1477	protein flavinylation
YEY1_RS15880	COG2871	sodium ion transport
YEY1_RS15885	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_RS15890	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_RS15895	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_RS15900	COG1805	sodium ion transport
YEY1_RS15905	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YEY1_RS15910	COG3034	peptidoglycan biosynthetic process
YEY1_RS15915	COG0121	glutamine amidotransferase
YEY1_RS15925	COG1960	acyl-CoA dehydrogenase activity
YEY1_RS15930	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YEY1_RS15950	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
YEY1_RS15955	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YEY1_RS15960	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YEY1_RS15965	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
YEY1_RS15970	COG0235	Class ii aldolase
YEY1_RS15975	COG0436	Aminotransferase
YEY1_RS15990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YEY1_RS16000	COG0765	amino acid transport
YEY1_RS16005	COG0765	amino acid transport
YEY1_RS16045	COG2814	Major facilitator Superfamily
YEY1_RS16050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YEY1_RS16060	COG1846	Transcriptional regulator
YEY1_RS16065	COG1538	Outer membrane efflux protein
YEY1_RS16070	COG1566	PFAM secretion protein HlyD family protein
YEY1_RS16075	COG2814	Major facilitator Superfamily
YEY1_RS16090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YEY1_RS16095	COG3118	belongs to the thioredoxin family
YEY1_RS16100	COG3148	PFAM DTW domain containing protein
YEY1_RS16105	COG1042	CoA-binding domain protein
YEY1_RS16105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YEY1_RS16105	COG0045	succinate-CoA ligase (ADP-forming) activity
YEY1_RS16110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YEY1_RS16115	COG5544	Lipoprotein
YEY1_RS16145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YEY1_RS16150	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YEY1_RS16160	COG0564	pseudouridine synthase activity
YEY1_RS16170	COG0542	response to heat
YEY1_RS16180	COG1605	Chorismate mutase
YEY1_RS16180	COG0077	Prephenate dehydratase
YEY1_RS16185	COG0287	Prephenate dehydrogenase
YEY1_RS16185	COG1605	Chorismate mutase
YEY1_RS16190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YEY1_RS16195	COG3279	Response regulator of the LytR AlgR family
YEY1_RS16200	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YEY1_RS16205	COG3137	Salt-induced outer membrane protein
YEY1_RS16210	COG0335	large ribosomal subunit rRNA binding
YEY1_RS16215	COG0336	Belongs to the RNA methyltransferase TrmD family
YEY1_RS16220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YEY1_RS16225	COG0228	four-way junction DNA binding
YEY1_RS16230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YEY1_RS16235	COG4137	Cytochrome C assembly protein
YEY1_RS16240	COG4536	flavin adenine dinucleotide binding
YEY1_RS16245	COG1854	S-ribosylhomocysteine lyase activity
YEY1_RS16250	COG2918	glutathione biosynthetic process
YEY1_RS16255	COG1238	metal cluster binding
YEY1_RS16260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_RS16280	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YEY1_RS16285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YEY1_RS16290	COG2137	regulation of response to DNA damage stimulus
YEY1_RS16295	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YEY1_RS16315	COG3381	protein complex oligomerization
YEY1_RS16320	COG3302	dmso reductase anchor subunit
YEY1_RS16325	COG0437	4 iron, 4 sulfur cluster binding
YEY1_RS16330	COG0243	molybdopterin cofactor binding
YEY1_RS16335	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_RS16335	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YEY1_RS16350	COG4177	L-phenylalanine transmembrane transporter activity
YEY1_RS16355	COG1137	ATPase activity
YEY1_RS16360	COG0410	ABC transporter
YEY1_RS16415	COG0640	Transcriptional regulator
YEY1_RS16420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YEY1_RS16435	COG1858	cytochrome C peroxidase
YEY1_RS16440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YEY1_RS16450	COG1028	Short-chain dehydrogenase reductase Sdr
YEY1_RS16470	COG1538	Outer membrane efflux protein
YEY1_RS16480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YEY1_RS16510	COG3539	Fimbrial protein
YEY1_RS16515	COG3539	Fimbrial protein
YEY1_RS16525	COG3121	Chaperone
YEY1_RS16530	COG3188	usher protein
YEY1_RS16555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YEY1_RS16560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YEY1_RS16565	COG4942	peptidase
YEY1_RS16565	COG1388	LysM domain
YEY1_RS16575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YEY1_RS16580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YEY1_RS16585	COG0585	pseudouridine synthase activity
YEY1_RS16590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YEY1_RS16600	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YEY1_RS16610	COG0529	Catalyzes the synthesis of activated sulfate
YEY1_RS16615	COG2895	sulfate adenylyltransferase (ATP) activity
YEY1_RS16620	COG0175	sulfate reduction
YEY1_RS16625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YEY1_RS16625	COG1648	precorrin-2 dehydrogenase activity
YEY1_RS16630	COG2234	aminopeptidase activity
YEY1_RS16650	COG0175	sulfate reduction
YEY1_RS16655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YEY1_RS16660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YEY1_RS16665	COG0720	synthase
YEY1_RS16685	COG0602	queuosine metabolic process
YEY1_RS16720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YEY1_RS16725	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YEY1_RS16730	COG0583	DNA-binding transcription factor activity
YEY1_RS16740	COG1279	arginine transmembrane transporter activity
YEY1_RS16760	COG0191	fructose-bisphosphate aldolase activity
YEY1_RS16765	COG0126	phosphoglycerate kinase activity
YEY1_RS16770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YEY1_RS16775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YEY1_RS16780	COG0501	Belongs to the peptidase M48B family
YEY1_RS16790	COG1166	arginine decarboxylase activity
YEY1_RS16795	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YEY1_RS16810	COG0640	Transcriptional regulator
YEY1_RS16815	COG3091	SprT-like family
YEY1_RS16820	COG2356	endonuclease I
YEY1_RS16825	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YEY1_RS16830	COG0189	ligase activity
YEY1_RS16835	COG1678	Uncharacterized ACR, COG1678
YEY1_RS16840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YEY1_RS16845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YEY1_RS16855	COG2805	Type II/IV secretion system protein
YEY1_RS16860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YEY1_RS16865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YEY1_RS16870	COG0762	integral membrane protein
YEY1_RS16875	COG1872	DUF167
YEY1_RS16880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YEY1_RS16885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YEY1_RS16900	COG3171	Protein conserved in bacteria
YEY1_RS16905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YEY1_RS16910	COG1194	a g-specific adenine glycosylase
YEY1_RS16915	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YEY1_RS16920	COG0741	lytic transglycosylase activity
YEY1_RS16930	COG1982	Orn Lys Arg decarboxylase major
YEY1_RS16945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YEY1_RS16990	COG0531	amino acid
YEY1_RS16995	COG1982	Orn Lys Arg decarboxylase major
YEY1_RS17010	COG1289	transmembrane transporter activity
YEY1_RS17035	COG0024	Methionine aminopeptidase
YEY1_RS17040	COG4604	ABC transporter, ATP-binding protein
YEY1_RS17045	COG4605	iron ion homeostasis
YEY1_RS17055	COG4607	ABC-type enterochelin transport system periplasmic component
YEY1_RS17070	COG0697	spore germination
YEY1_RS17075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YEY1_RS17090	COG0477	Major facilitator Superfamily
YEY1_RS17095	COG1609	Transcriptional regulator
YEY1_RS17105	COG1283	sodium-dependent phosphate transmembrane transporter activity
YEY1_RS17120	COG0477	Major facilitator Superfamily
YEY1_RS17145	COG5001	Diguanylate cyclase
YEY1_RS17160	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
YEY1_RS17170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
YEY1_RS17175	COG0309	Hydrogenase expression formation protein (HypE)
YEY1_RS17180	COG0409	Hydrogenase expression formation protein
YEY1_RS17185	COG0298	carbon dioxide binding
YEY1_RS17190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YEY1_RS17200	COG1773	rubredoxin
YEY1_RS17205	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
YEY1_RS17210	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
YEY1_RS17215	COG5557	Pfam Polysulphide reductase, NrfD
YEY1_RS17220	COG0437	4 iron, 4 sulfur cluster binding
YEY1_RS17225	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
YEY1_RS17235	COG3133	Outer membrane lipoprotein
YEY1_RS17245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YEY1_RS17250	COG1191	sigma factor activity
YEY1_RS17270	COG1516	flagellar protein fliS
YEY1_RS17275	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YEY1_RS17280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YEY1_RS17290	COG3710	Transcriptional regulator
YEY1_RS17320	COG1706	bacterial-type flagellum-dependent cell motility
YEY1_RS17330	COG4786	Flagellar basal body rod
YEY1_RS17345	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YEY1_RS17350	COG1558	bacterial-type flagellum-dependent cell motility
YEY1_RS17355	COG1815	bacterial-type flagellum-dependent cell motility
YEY1_RS17395	COG1136	(ABC) transporter
YEY1_RS17395	COG0577	efflux transmembrane transporter activity
YEY1_RS17480	COG4964	Belongs to the GSP D family
YEY1_RS17530	COG0848	biopolymer transport protein
YEY1_RS17540	COG0626	cystathionine gamma-synthase activity
YEY1_RS17545	COG0586	Pfam SNARE associated Golgi protein
YEY1_RS17550	COG2207	Transcriptional regulator
YEY1_RS17555	COG1979	alcohol dehydrogenase
YEY1_RS17560	COG0656	L-ascorbic acid biosynthetic process
YEY1_RS17570	COG2132	Multicopper oxidase
YEY1_RS17585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YEY1_RS17595	COG2249	NAD(P)H dehydrogenase (quinone) activity
YEY1_RS17600	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YEY1_RS17615	COG3150	esterase
YEY1_RS17620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YEY1_RS17625	COG3151	Protein conserved in bacteria
YEY1_RS17630	COG0494	nUDIX hydrolase
YEY1_RS17635	COG1538	Outer membrane efflux protein
YEY1_RS17640	COG5463	Belongs to the UPF0441 family
YEY1_RS17645	COG0754	glutathionylspermidine amidase activity
YEY1_RS17650	COG3384	dioxygenase
YEY1_RS17655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YEY1_RS17665	COG0531	amino acid
YEY1_RS17670	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YEY1_RS17670	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YEY1_RS17675	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YEY1_RS17680	COG3025	triphosphatase activity
YEY1_RS17685	COG4991	sh3 domain protein
YEY1_RS17690	COG0617	tRNA 3'-terminal CCA addition
YEY1_RS17695	COG1968	undecaprenyl-diphosphatase activity
YEY1_RS17700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YEY1_RS17705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YEY1_RS17710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YEY1_RS17715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YEY1_RS17720	COG0358	DNA primase activity
YEY1_RS17815	COG2856	Zn peptidase
YEY1_RS17895	COG4695	Portal protein
YEY1_RS17960	COG4974	Belongs to the 'phage' integrase family
YEY1_RS17965	COG3876	Protein conserved in bacteria
YEY1_RS17975	COG1472	Belongs to the glycosyl hydrolase 3 family
YEY1_RS17985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
YEY1_RS17990	COG1263	PTS System
YEY1_RS17990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS18000	COG0531	amino acid
YEY1_RS18005	COG0076	glutamate decarboxylase activity
YEY1_RS18020	COG3247	response to pH
YEY1_RS18030	COG1902	pentaerythritol trinitrate reductase activity
YEY1_RS18030	COG0446	pyridine nucleotide-disulphide oxidoreductase
YEY1_RS18040	COG2813	Specifically methylates the guanine in position
YEY1_RS18060	COG1451	nucleotide metabolic process
YEY1_RS18065	COG0673	inositol 2-dehydrogenase activity
YEY1_RS18070	COG0861	Integral membrane protein TerC family
YEY1_RS18075	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
YEY1_RS18085	COG2721	sulfolactate sulfo-lyase activity
YEY1_RS18090	COG0246	Mannitol dehydrogenase
YEY1_RS18095	COG1904	glucuronate isomerase
YEY1_RS18100	COG2271	Major facilitator Superfamily
YEY1_RS18115	COG0586	Pfam SNARE associated Golgi protein
YEY1_RS18130	COG4575	ribosome binding
YEY1_RS18135	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YEY1_RS18145	COG2259	Doxx family
YEY1_RS18150	COG0435	Glutathione S-transferase
YEY1_RS18155	COG0583	DNA-binding transcription factor activity
YEY1_RS18165	COG1741	Belongs to the pirin family
YEY1_RS18175	COG0667	Aldo Keto reductase
YEY1_RS18195	COG3121	Chaperone
YEY1_RS18250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YEY1_RS18260	COG0792	nuclease activity
YEY1_RS18265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YEY1_RS18270	COG2823	Periplasmic or secreted lipoprotein
YEY1_RS18285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YEY1_RS18290	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YEY1_RS18300	COG0784	Response regulator, receiver
YEY1_RS18300	COG2198	Histidine kinase
YEY1_RS18300	COG5002	protein histidine kinase activity
YEY1_RS18310	COG0069	glutamate synthase activity
YEY1_RS18310	COG0067	glutamate synthase
YEY1_RS18310	COG0070	glutamate synthase
YEY1_RS18315	COG0493	'glutamate synthase
YEY1_RS18330	COG2969	positive regulation of protein catabolic process
YEY1_RS18335	COG0625	glutathione transferase activity
YEY1_RS18340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YEY1_RS18345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YEY1_RS18350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YEY1_RS18355	COG3105	Protein conserved in bacteria
YEY1_RS18360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YEY1_RS18365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YEY1_RS18370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YEY1_RS18375	COG5007	Belongs to the BolA IbaG family
YEY1_RS18380	COG3113	response to antibiotic
YEY1_RS18385	COG2854	intermembrane phospholipid transfer
YEY1_RS18390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YEY1_RS18395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YEY1_RS18400	COG1127	ABC transporter
YEY1_RS18410	COG0530	calcium, potassium:sodium antiporter activity
YEY1_RS18415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YEY1_RS18415	COG0517	IMP dehydrogenase activity
YEY1_RS18420	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YEY1_RS18425	COG3117	lipopolysaccharide transmembrane transporter activity
YEY1_RS18430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YEY1_RS18435	COG1137	ATPase activity
YEY1_RS18440	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YEY1_RS18455	COG1660	Displays ATPase and GTPase activities
YEY1_RS18460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS18475	COG0540	Belongs to the ATCase OTCase family
YEY1_RS18480	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
YEY1_RS18490	COG2308	Evidence 4 Homologs of previously reported genes of
YEY1_RS18510	COG0366	Alpha amylase catalytic
YEY1_RS18515	COG1263	PTS System
YEY1_RS18515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YEY1_RS18535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YEY1_RS18545	COG3093	addiction module antidote protein HigA
YEY1_RS18550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YEY1_RS18550	COG3711	transcriptional antiterminator
YEY1_RS18555	COG2706	6-phosphogluconolactonase activity
YEY1_RS18570	COG3964	amidohydrolase
YEY1_RS18600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YEY1_RS18605	COG3783	Cytochrome b(562)
YEY1_RS18615	COG0312	modulator of DNA gyrase
YEY1_RS18620	COG3028	Belongs to the UPF0307 family
YEY1_RS18625	COG2732	(Barnase) inhibitor
YEY1_RS18640	COG1289	transmembrane transporter activity
YEY1_RS18645	COG1566	PFAM secretion protein HlyD family protein
YEY1_RS18655	COG0583	DNA-binding transcription factor activity
YEY1_RS18715	COG0312	modulator of DNA gyrase
YEY1_RS18720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YEY1_RS18725	COG3164	Protein of unknown function
YEY1_RS18735	COG0424	maF-like protein
YEY1_RS18740	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YEY1_RS18745	COG1792	Involved in formation and maintenance of cell shape
YEY1_RS18750	COG1077	Cell shape determining protein MreB Mrl
YEY1_RS18755	COG2199	diguanylate cyclase activity
YEY1_RS18755	COG2200	EAL domain
YEY1_RS18760	COG0604	alcohol dehydrogenase
YEY1_RS18770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YEY1_RS18775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YEY1_RS18780	COG0511	ligase activity, forming carbon-carbon bonds
YEY1_RS18785	COG0439	Biotin carboxylase
YEY1_RS18790	COG3924	membrane
YEY1_RS18795	COG4145	pantothenate transmembrane transporter activity
YEY1_RS18800	COG2264	protein methyltransferase activity
YEY1_RS18810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YEY1_RS18815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YEY1_RS18825	COG3133	Outer membrane lipoprotein
YEY1_RS18830	COG1278	Cold shock
YEY1_RS18835	COG1278	Cold shock
YEY1_RS18840	COG0471	metal ion transport
YEY1_RS18845	COG1560	Kdo2-lipid A biosynthetic process
YEY1_RS18865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS18870	COG4597	amino acid ABC transporter
YEY1_RS18875	COG0765	amino acid transport
YEY1_RS18880	COG1126	abc transporter atp-binding protein
YEY1_RS18890	COG1380	Effector of murein hydrolase LrgA
YEY1_RS18895	COG0583	DNA-binding transcription factor activity
YEY1_RS18900	COG0025	NhaP-type Na H and K H
YEY1_RS18905	COG2252	PERMEase
YEY1_RS18920	COG3550	peptidyl-serine autophosphorylation
YEY1_RS18930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YEY1_RS18935	COG2315	Protein conserved in bacteria
YEY1_RS18940	COG1448	Aminotransferase
YEY1_RS18970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YEY1_RS18980	COG0735	belongs to the Fur family
YEY1_RS18985	COG3237	CsbD-like
YEY1_RS18990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YEY1_RS18995	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YEY1_RS19000	COG2937	Belongs to the GPAT DAPAT family
YEY1_RS19005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YEY1_RS19010	COG3161	chorismate lyase activity
YEY1_RS19025	COG4580	involved in the transport of maltose and maltodextrins
YEY1_RS19040	COG2182	Extracellular solute-binding protein
YEY1_RS19045	COG1175	transmembrane transport
YEY1_RS19050	COG3833	ABC-type maltose transport systems, permease component
YEY1_RS19060	COG0166	Belongs to the GPI family
YEY1_RS19065	COG0527	aspartate kinase activity
YEY1_RS19090	COG1414	Transcriptional regulator
YEY1_RS19095	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YEY1_RS19100	COG2224	Isocitrate lyase
YEY1_RS19105	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YEY1_RS19110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
YEY1_RS19160	COG0138	bifunctional purine biosynthesis protein purh
YEY1_RS19165	COG0151	Belongs to the GarS family
YEY1_RS19185	COG1515	deoxyribonuclease V activity
YEY1_RS19190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YEY1_RS19195	COG2816	NAD+ diphosphatase activity
YEY1_RS19200	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
YEY1_RS19215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YEY1_RS19220	COG2104	thiamine diphosphate biosynthetic process
YEY1_RS19225	COG2022	thiamine diphosphate biosynthetic process
YEY1_RS19240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YEY1_RS19245	COG0085	RNA polymerase activity
YEY1_RS19250	COG0222	ribosome binding
YEY1_RS19255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YEY1_RS19260	COG0081	regulation of translation
YEY1_RS19265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YEY1_RS19270	COG0250	Participates in transcription elongation, termination and antitermination
YEY1_RS19280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YEY1_RS19315	COG1072	(Pantothenic acid kinase))
YEY1_RS19320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YEY1_RS19320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YEY1_RS19370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YEY1_RS19375	COG1739	Uncharacterized protein family UPF0029
YEY1_RS19380	COG0006	proline dipeptidase activity
YEY1_RS19385	COG1250	3-hydroxyacyl-CoA dehydrogenase
YEY1_RS19385	COG1024	Enoyl-CoA hydratase
YEY1_RS19390	COG0183	Belongs to the thiolase family
YEY1_RS19400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YEY1_RS19420	COG0805	protein transport
YEY1_RS19425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YEY1_RS19430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YEY1_RS19435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YEY1_RS19445	COG2226	methyltransferase
YEY1_RS19450	COG1322	Protein conserved in bacteria
YEY1_RS19455	COG0586	Pfam SNARE associated Golgi protein
YEY1_RS19460	COG1966	Carbon starvation protein
YEY1_RS19480	COG0412	Dienelactone hydrolase
YEY1_RS19485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YEY1_RS19490	COG0583	DNA-binding transcription factor activity
YEY1_RS19495	COG0697	spore germination
YEY1_RS19500	COG0679	Auxin Efflux Carrier
YEY1_RS19505	COG0584	glycerophosphoryl diester phosphodiesterase
YEY1_RS19510	COG3842	ATPase activity
YEY1_RS19515	COG0395	ABC-type sugar transport system, permease component
YEY1_RS19520	COG1175	transmembrane transport
YEY1_RS19560	COG0410	ABC transporter
YEY1_RS19570	COG4177	L-phenylalanine transmembrane transporter activity
YEY1_RS19580	COG0683	leucine binding
YEY1_RS19610	COG2177	Part of the ABC transporter FtsEX involved in
YEY1_RS19615	COG2884	Cell division ATP-binding protein ftsE
YEY1_RS19620	COG0552	protein localization to endoplasmic reticulum
YEY1_RS19625	COG0742	ribosomal rna small subunit methyltransferase
YEY1_RS19630	COG3776	membrane
YEY1_RS19645	COG3714	YhhN family
YEY1_RS19650	COG2217	Heavy metal translocating P-type atpase
YEY1_RS19655	COG0425	Belongs to the sulfur carrier protein TusA family
YEY1_RS19660	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YEY1_RS19670	COG0247	lactate metabolic process
YEY1_RS19675	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
YEY1_RS19680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YEY1_RS19685	COG2271	Major facilitator Superfamily
YEY1_RS19690	COG0584	glycerophosphoryl diester phosphodiesterase
YEY1_RS19700	COG0561	phosphatase activity
YEY1_RS19705	COG2267	carboxylic ester hydrolase activity
YEY1_RS19710	COG1280	lysine exporter protein (LysE YggA)
YEY1_RS19715	COG1280	lysine exporter protein (LysE YggA)
YEY1_RS19720	COG0514	ATP-dependent DNA helicase (RecQ)
YEY1_RS19725	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YEY1_RS19730	COG2050	protein possibly involved in aromatic compounds catabolism
YEY1_RS19745	COG5564	TIM-barrel signal transduction protein
YEY1_RS19750	COG5441	Belongs to the UPF0261 family
YEY1_RS19760	COG0210	DNA helicase
YEY1_RS19765	COG1011	Hydrolase
YEY1_RS19770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YEY1_RS19775	COG3159	Protein conserved in bacteria
YEY1_RS19780	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YEY1_RS19790	COG1965	Belongs to the frataxin family
YEY1_RS19795	COG3072	Adenylate cyclase
YEY1_RS19800	COG0181	hydroxymethylbilane synthase activity
YEY1_RS19805	COG1587	Uroporphyrinogen-III synthase
YEY1_RS19810	COG2959	enzyme of heme biosynthesis
YEY1_RS19815	COG3071	HemY protein
YEY1_RS19865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YEY1_RS19870	COG2244	polysaccharide biosynthetic process
YEY1_RS19875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YEY1_RS19880	COG0456	acetyltransferase
YEY1_RS19885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YEY1_RS19895	COG1088	dTDP-glucose 4,6-dehydratase activity
YEY1_RS19900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YEY1_RS19905	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YEY1_RS19910	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YEY1_RS19915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YEY1_RS19920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YEY1_RS19925	COG3118	belongs to the thioredoxin family
YEY1_RS19935	COG0248	Ppx GppA phosphatase
YEY1_RS19950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YEY1_RS19960	COG3121	Chaperone
YEY1_RS19975	COG3121	Chaperone
YEY1_RS20000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YEY1_RS20005	COG0583	DNA-binding transcription factor activity
YEY1_RS20030	COG0129	dihydroxy-acid dehydratase activity
YEY1_RS20035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YEY1_RS20040	COG3978	acetolactate synthase activity
YEY1_RS20060	COG3085	chromosome segregation
YEY1_RS20065	COG0583	DNA-binding transcription factor activity
YEY1_RS20070	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS20075	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS20080	COG1129	ABC transporter
YEY1_RS20085	COG1879	ABC-type sugar transport system periplasmic component
YEY1_RS20130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YEY1_RS20140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YEY1_RS20150	COG1309	transcriptional regulator
YEY1_RS20155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_RS20165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YEY1_RS20165	COG0678	peroxiredoxin activity
YEY1_RS20170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YEY1_RS20210	COG1629	transport
YEY1_RS20215	COG0165	Argininosuccinate lyase
YEY1_RS20220	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YEY1_RS20235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YEY1_RS20245	COG0527	aspartate kinase activity
YEY1_RS20245	COG0460	homoserine dehydrogenase
YEY1_RS20250	COG0626	cystathionine gamma-synthase activity
YEY1_RS20255	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YEY1_RS20260	COG0254	rRNA binding
YEY1_RS20265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YEY1_RS20270	COG1609	Transcriptional regulator
YEY1_RS20275	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YEY1_RS20280	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YEY1_RS20285	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YEY1_RS20290	COG1575	Belongs to the MenA family. Type 1 subfamily
YEY1_RS20295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YEY1_RS20300	COG3074	FtsZ-dependent cytokinesis
YEY1_RS20310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YEY1_RS20320	COG1494	fructose-1,6-bisphosphatase
YEY1_RS20330	COG2814	Major facilitator Superfamily
YEY1_RS20350	COG3152	Membrane
YEY1_RS20360	COG0149	triose-phosphate isomerase activity
YEY1_RS20370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YEY1_RS20380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
YEY1_RS20465	COG4695	Portal protein
YEY1_RS20480	COG0653	protein targeting
YEY1_RS20505	COG4974	Belongs to the 'phage' integrase family
YEY1_RS20510	COG3678	ATP-independent chaperone mediated protein folding
YEY1_RS20515	COG0745	RESPONSE REGULATOR receiver
YEY1_RS20520	COG2205	protein histidine kinase activity
YEY1_RS20525	COG2169	Transcriptional regulator
YEY1_RS20525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YEY1_RS20530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YEY1_RS20535	COG1045	serine acetyltransferase
YEY1_RS20540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YEY1_RS20545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YEY1_RS20550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YEY1_RS20555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YEY1_RS20560	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
YEY1_RS20565	COG4942	peptidase
YEY1_RS20570	COG2861	carbohydrate metabolic process
YEY1_RS20585	COG1063	alcohol dehydrogenase
YEY1_RS20590	COG0156	8-amino-7-oxononanoate synthase activity
YEY1_RS20595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YEY1_RS20600	COG0859	PFAM glycosyl transferase family 9
YEY1_RS20605	COG0859	PFAM glycosyl transferase family 9
YEY1_RS20610	COG1519	Transferase
YEY1_RS20620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YEY1_RS20625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YEY1_RS20630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YEY1_RS20635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YEY1_RS20645	COG2003	Belongs to the UPF0758 family
YEY1_RS20650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YEY1_RS20655	COG0756	dUTP diphosphatase activity
YEY1_RS20660	COG1309	transcriptional regulator
YEY1_RS20670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YEY1_RS20675	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YEY1_RS20680	COG1561	YicC-like family, N-terminal region
YEY1_RS20695	COG5001	Diguanylate cyclase
YEY1_RS20700	COG1024	Enoyl-CoA hydratase
YEY1_RS20705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YEY1_RS20715	COG2860	membrane
YEY1_RS20720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YEY1_RS20730	COG1758	RNA polymerase activity
YEY1_RS20735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YEY1_RS20740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YEY1_RS20745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YEY1_RS20760	COG0786	glutamate:sodium symporter activity
YEY1_RS20765	COG2233	PERMEase
YEY1_RS20770	COG2982	Protein involved in outer membrane biogenesis
YEY1_RS20790	COG3423	Transcriptional regulator
YEY1_RS20795	COG0456	acetyltransferase
YEY1_RS20800	COG1490	D-aminoacyl-tRNA deacylase activity
YEY1_RS20805	COG1295	ribonuclease BN
YEY1_RS20810	COG1011	Hydrolase
YEY1_RS20825	COG3852	Histidine kinase
YEY1_RS20840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YEY1_RS20850	COG3078	GTPase activator activity
YEY1_RS20855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YEY1_RS20860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YEY1_RS20860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YEY1_RS20865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YEY1_RS20870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YEY1_RS20875	COG3084	Protein conserved in bacteria
YEY1_RS20885	COG1763	Mo-molybdopterin cofactor biosynthetic process
YEY1_RS20920	COG2186	Transcriptional regulator
YEY1_RS20925	COG0477	Major facilitator Superfamily
YEY1_RS20930	COG1609	Transcriptional regulator
YEY1_RS20935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YEY1_RS20940	COG1879	ABC-type sugar transport system periplasmic component
YEY1_RS20945	COG1172	Belongs to the binding-protein-dependent transport system permease family
YEY1_RS20955	COG1869	D-ribose catabolic process
YEY1_RS20960	COG3158	transport of potassium into the cell
YEY1_RS20965	COG0714	Associated with various cellular activities
YEY1_RS20970	COG2425	protein containing a von Willebrand factor type A (vWA) domain
YEY1_RS20980	COG2502	aspartate--ammonia ligase
YEY1_RS20985	COG1522	sequence-specific DNA binding
YEY1_RS20990	COG0716	FMN binding
YEY1_RS20995	COG0445	tRNA wobble uridine modification
YEY1_RS21000	COG0357	Ribosomal RNA small subunit methyltransferase G
YEY1_RS21005	COG3312	ion transport
YEY1_RS21010	COG0356	it plays a direct role in the translocation of protons across the membrane
YEY1_RS21020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YEY1_RS21025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YEY1_RS21030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YEY1_RS21035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YEY1_RS21040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YEY1_RS21045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YEY1_RS21050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YEY1_RS21060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YEY1_RS21065	COG0573	inorganic phosphate transmembrane transporter activity
YEY1_RS21070	COG0581	inorganic phosphate transmembrane transporter activity
YEY1_RS21080	COG0704	Plays a role in the regulation of phosphate uptake
YEY1_RS21090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YEY1_RS21095	COG0765	amino acid transport
YEY1_RS21100	COG0765	amino acid transport
YEY1_RS21105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YEY1_RS21110	COG2252	PERMEase
YEY1_RS21120	COG4566	intracellular signal transduction
YEY1_RS21130	COG0431	NADPH-dependent FMN reductase
YEY1_RS21135	COG0840	transmembrane signaling receptor activity
YEY1_RS21140	COG2011	ABC-type metal ion transport system permease component
YEY1_RS21155	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YEY1_RS21160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YEY1_RS21165	COG0706	membrane insertase activity
YEY1_RS21175	COG0594	ribonuclease P activity
YEY1_RS21180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YEY1_RS21210	COG3609	addiction module antidote protein, CC2985 family
YEY1_RS21325	COG4792	protein secretion
YEY1_RS21330	COG4791	protein targeting
YEY1_RS21335	COG4794	Type iii secretion
YEY1_RS21340	COG4790	Type iii secretion
YEY1_RS21430	COG4886	Leucine-rich repeat (LRR) protein
YEY1_RS21430	COG4886	Leucine-rich repeat (LRR) protein
YEY1_RS21575	COG5599	Phosphatase
YEY1_RS21630	COG0640	Transcriptional regulator
YEY1_RS21635	COG0431	NADPH-dependent FMN reductase