locus-tag	class	description
AW19_RS00020	COG1858	cytochrome C peroxidase
AW19_RS00040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AW19_RS00160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AW19_RS00160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AW19_RS00300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW19_RS00340	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS00350	COG1858	cytochrome C peroxidase
AW19_RS00360	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AW19_RS00365	COG0640	Transcriptional regulator
AW19_RS00425	COG0410	ABC transporter
AW19_RS00430	COG1137	ATPase activity
AW19_RS00435	COG4177	L-phenylalanine transmembrane transporter activity
AW19_RS00450	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AW19_RS00450	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AW19_RS00455	COG0243	molybdopterin cofactor binding
AW19_RS00460	COG0437	4 iron, 4 sulfur cluster binding
AW19_RS00465	COG3302	dmso reductase anchor subunit
AW19_RS00470	COG3381	protein complex oligomerization
AW19_RS00485	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AW19_RS00490	COG2137	regulation of response to DNA damage stimulus
AW19_RS00495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW19_RS00500	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AW19_RS00525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW19_RS00530	COG1238	metal cluster binding
AW19_RS00535	COG2918	glutathione biosynthetic process
AW19_RS00540	COG1854	S-ribosylhomocysteine lyase activity
AW19_RS00545	COG4536	flavin adenine dinucleotide binding
AW19_RS00550	COG4137	Cytochrome C assembly protein
AW19_RS00555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW19_RS00565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AW19_RS00570	COG0336	Belongs to the RNA methyltransferase TrmD family
AW19_RS00575	COG0335	large ribosomal subunit rRNA binding
AW19_RS00580	COG3137	Salt-induced outer membrane protein
AW19_RS00585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW19_RS00590	COG3279	Response regulator of the LytR AlgR family
AW19_RS00595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AW19_RS00600	COG1605	Chorismate mutase
AW19_RS00600	COG0287	Prephenate dehydrogenase
AW19_RS00605	COG0077	Prephenate dehydratase
AW19_RS00605	COG1605	Chorismate mutase
AW19_RS00610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW19_RS00615	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW19_RS00620	COG0564	pseudouridine synthase activity
AW19_RS00625	COG1496	oxidoreductase activity
AW19_RS00630	COG0542	response to heat
AW19_RS00665	COG0656	L-ascorbic acid biosynthetic process
AW19_RS00670	COG0583	DNA-binding transcription factor activity
AW19_RS00675	COG2814	Major facilitator Superfamily
AW19_RS00685	COG3021	interspecies interaction between organisms
AW19_RS00690	COG0741	lytic transglycosylase activity
AW19_RS00690	COG1388	LysM domain
AW19_RS00695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW19_RS00700	COG2226	methyltransferase
AW19_RS00705	COG0328	RNA-DNA hybrid ribonuclease activity
AW19_RS00710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW19_RS00720	COG2113	Glycine betaine
AW19_RS00725	COG4176	ABC-type proline glycine betaine transport system permease component
AW19_RS00735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW19_RS00745	COG1780	Probably involved in ribonucleotide reductase function
AW19_RS00750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW19_RS00755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW19_RS00765	COG4575	ribosome binding
AW19_RS00800	COG1278	Cold shock
AW19_RS00820	COG0747	negative chemotaxis
AW19_RS00830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW19_RS00840	COG1124	(ABC) transporter
AW19_RS00850	COG0831	urea catabolic process
AW19_RS00855	COG0832	Belongs to the urease beta subunit family
AW19_RS00860	COG0804	urea catabolic process
AW19_RS00865	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AW19_RS00875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AW19_RS00880	COG0829	nickel cation binding
AW19_RS00885	COG4413	Urea transporter
AW19_RS00890	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AW19_RS00900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW19_RS00915	COG0667	Aldo Keto reductase
AW19_RS00920	COG2133	pyrroloquinoline quinone binding
AW19_RS00925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW19_RS00930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW19_RS00935	COG2723	6-phospho-beta-galactosidase activity
AW19_RS00940	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW19_RS00945	COG1917	Cupin 2, conserved barrel domain protein
AW19_RS00945	COG2169	Transcriptional regulator
AW19_RS00950	COG3394	polysaccharide catabolic process
AW19_RS00960	COG2003	Belongs to the UPF0758 family
AW19_RS00995	COG3311	Transcriptional regulator
AW19_RS01020	COG1061	Type III restriction enzyme res subunit
AW19_RS01035	COG0582	viral genome integration into host DNA
AW19_RS01040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AW19_RS01045	COG2867	negative regulation of translational initiation
AW19_RS01055	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW19_RS01060	COG0497	DNA recombination
AW19_RS01065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AW19_RS01070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AW19_RS01075	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AW19_RS01080	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AW19_RS01085	COG0513	Belongs to the DEAD box helicase family
AW19_RS01090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW19_RS01095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW19_RS01105	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AW19_RS01115	COG3086	response to oxidative stress
AW19_RS01125	COG0481	GTPase activity
AW19_RS01140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW19_RS01145	COG1381	Involved in DNA repair and RecF pathway recombination
AW19_RS01150	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AW19_RS01155	COG0736	holo-[acyl-carrier-protein] synthase activity
AW19_RS01160	COG2610	gluconate transmembrane transporter activity
AW19_RS01165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW19_RS01170	COG1737	Transcriptional regulator
AW19_RS01180	COG3423	Transcriptional regulator
AW19_RS01190	COG0560	Phosphoserine phosphatase
AW19_RS01205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AW19_RS01220	COG2205	protein histidine kinase activity
AW19_RS01225	COG3170	Tfp pilus assembly protein FimV
AW19_RS01230	COG2204	response regulator
AW19_RS01235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AW19_RS01235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW19_RS01240	COG0347	Belongs to the P(II) protein family
AW19_RS01250	COG2188	Transcriptional regulator
AW19_RS01255	COG1017	nitric oxide dioxygenase activity
AW19_RS01255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW19_RS01260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AW19_RS01265	COG2814	Major facilitator Superfamily
AW19_RS01270	COG3711	transcriptional antiterminator
AW19_RS01275	COG3683	transport system, periplasmic component
AW19_RS01280	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AW19_RS01285	COG0483	inositol monophosphate 1-phosphatase activity
AW19_RS01290	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AW19_RS01295	COG1959	2 iron, 2 sulfur cluster binding
AW19_RS01305	COG0822	iron-sulfur transferase activity
AW19_RS01315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AW19_RS01320	COG0443	Heat shock 70 kDa protein
AW19_RS01325	COG0633	Ferredoxin
AW19_RS01330	COG2975	iron-sulfur cluster assembly
AW19_RS01350	COG2373	Large extracellular alpha-helical protein
AW19_RS01355	COG4953	penicillin-binding protein 1C
AW19_RS01370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AW19_RS01395	COG0124	histidyl-tRNA synthetase
AW19_RS01400	COG2976	Protein conserved in bacteria
AW19_RS01405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AW19_RS01410	COG1160	GTP binding
AW19_RS01420	COG1645	bacterial-type flagellum-dependent swarming motility
AW19_RS01425	COG1570	exodeoxyribonuclease VII activity
AW19_RS01430	COG0517	IMP dehydrogenase activity
AW19_RS01430	COG0516	GMP reductase activity
AW19_RS01435	COG0519	Catalyzes the synthesis of GMP from XMP
AW19_RS01435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AW19_RS01440	COG0582	viral genome integration into host DNA
AW19_RS01675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AW19_RS01725	COG0351	phosphomethylpyrimidine kinase
AW19_RS01745	COG1349	DNA-binding transcription factor activity
AW19_RS01750	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS01755	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS01770	COG3730	PTS system glucitol sorbitol-specific
AW19_RS01775	COG1597	lipid kinase activity
AW19_RS01780	COG0826	peptidase U32
AW19_RS01785	COG3422	double-strand break repair
AW19_RS01790	COG0745	RESPONSE REGULATOR receiver
AW19_RS01795	COG2205	protein histidine kinase activity
AW19_RS01800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW19_RS01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS01820	COG0443	Heat shock 70 kDa protein
AW19_RS01825	COG3447	MASE1 domain protein
AW19_RS01825	COG5002	protein histidine kinase activity
AW19_RS01825	COG5001	Diguanylate cyclase
AW19_RS01830	COG2239	Acts as a magnesium transporter
AW19_RS01845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AW19_RS01850	COG0573	inorganic phosphate transmembrane transporter activity
AW19_RS01855	COG0581	inorganic phosphate transmembrane transporter activity
AW19_RS01870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW19_RS01875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW19_RS01880	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AW19_RS01885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AW19_RS01890	COG2233	PERMEase
AW19_RS01895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AW19_RS01900	COG1393	Belongs to the ArsC family
AW19_RS01905	COG4783	chaperone-mediated protein folding
AW19_RS01910	COG0628	permease
AW19_RS01915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW19_RS01920	COG2716	regulation of RNA biosynthetic process
AW19_RS01925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW19_RS01930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AW19_RS01935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AW19_RS01940	COG2321	neutral zinc metallopeptidase
AW19_RS01945	COG2707	UPF0756 membrane protein
AW19_RS01950	COG1444	tRNA N-acetyltransferase activity
AW19_RS01955	COG0400	carboxylic ester hydrolase activity
AW19_RS01965	COG1876	peptidase activity
AW19_RS01970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW19_RS01975	COG1393	Belongs to the ArsC family
AW19_RS02005	COG3842	ATPase activity
AW19_RS02010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW19_RS02020	COG2197	response regulator
AW19_RS02030	COG3062	negative regulation of establishment of protein localization
AW19_RS02035	COG0243	molybdopterin cofactor binding
AW19_RS02040	COG3043	anaerobic respiration
AW19_RS02045	COG3005	denitrification pathway
AW19_RS02060	COG0494	nUDIX hydrolase
AW19_RS02070	COG1671	Belongs to the UPF0178 family
AW19_RS02075	COG0408	coproporphyrinogen oxidase activity
AW19_RS02080	COG0456	acetyltransferase
AW19_RS02085	COG3111	PFAM Bacterial OB fold (BOF) protein
AW19_RS02095	COG2837	iron assimilation
AW19_RS02100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW19_RS02115	COG2731	YhcH YjgK YiaL family protein
AW19_RS02120	COG1737	Transcriptional regulator
AW19_RS02130	COG4150	thiosulfate binding
AW19_RS02135	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AW19_RS02140	COG4208	sulfate ABC transporter
AW19_RS02155	COG0745	RESPONSE REGULATOR receiver
AW19_RS02160	COG2205	protein histidine kinase activity
AW19_RS02170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW19_RS02175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS02195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AW19_RS02200	COG3530	Putative quorum-sensing-regulated virulence factor
AW19_RS02230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AW19_RS02250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW19_RS02270	COG0667	Aldo Keto reductase
AW19_RS02275	COG0583	DNA-binding transcription factor activity
AW19_RS02285	COG0837	glucose binding
AW19_RS02290	COG2223	nitrite transmembrane transporter activity
AW19_RS02295	COG3279	Response regulator of the LytR AlgR family
AW19_RS02300	COG3275	phosphorelay sensor kinase activity
AW19_RS02315	COG0436	Aminotransferase
AW19_RS02320	COG3038	cytochrome b561
AW19_RS02355	COG3381	protein complex oligomerization
AW19_RS02360	COG3302	dmso reductase anchor subunit
AW19_RS02365	COG0437	4 iron, 4 sulfur cluster binding
AW19_RS02370	COG0243	molybdopterin cofactor binding
AW19_RS02380	COG1280	lysine exporter protein (LysE YggA)
AW19_RS02400	COG2951	lytic endotransglycosylase activity
AW19_RS02405	COG0531	amino acid
AW19_RS02425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AW19_RS02430	COG1127	ABC transporter
AW19_RS02445	COG3038	cytochrome b561
AW19_RS02450	COG2353	YceI-like domain
AW19_RS02455	COG1609	Transcriptional regulator
AW19_RS02460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS02460	COG1263	PTS System
AW19_RS02465	COG2723	6-phospho-beta-galactosidase activity
AW19_RS02485	COG2824	Alkylphosphonate utilization operon protein PhnA
AW19_RS02490	COG2850	peptidyl-arginine hydroxylation
AW19_RS02495	COG5265	(ABC) transporter
AW19_RS02520	COG2197	response regulator
AW19_RS02525	COG1278	Cold shock
AW19_RS02540	COG3706	GGDEF domain
AW19_RS02545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW19_RS02550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AW19_RS02555	COG0321	lipoyl(octanoyl) transferase activity
AW19_RS02560	COG2921	Belongs to the UPF0250 family
AW19_RS02565	COG1686	Belongs to the peptidase S11 family
AW19_RS02570	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AW19_RS02575	COG0772	Belongs to the SEDS family
AW19_RS02580	COG0768	penicillin binding
AW19_RS02590	COG0799	negative regulation of ribosome biogenesis
AW19_RS02595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AW19_RS02600	COG1466	dna polymerase III delta subunit
AW19_RS02605	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AW19_RS02615	COG2888	peptidyl-tyrosine sulfation
AW19_RS02625	COG1126	abc transporter atp-binding protein
AW19_RS02630	COG0765	amino acid transport
AW19_RS02635	COG0765	amino acid transport
AW19_RS02650	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AW19_RS02655	COG4535	Mg2 and Co2 transporter CorC
AW19_RS02660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AW19_RS02665	COG1702	phosphate starvation-inducible protein PhoH
AW19_RS02670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW19_RS02675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW19_RS02705	COG0367	asparagine synthase
AW19_RS02710	COG0647	UMP catabolic process
AW19_RS02715	COG1940	carbohydrate kinase activity
AW19_RS02715	COG1846	Transcriptional regulator
AW19_RS02720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW19_RS02725	COG0363	glucosamine-6-phosphate deaminase activity
AW19_RS02730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS02730	COG1263	PTS System
AW19_RS02730	COG2190	(PTS) system
AW19_RS02735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AW19_RS02755	COG0735	belongs to the Fur family
AW19_RS02765	COG0840	transmembrane signaling receptor activity
AW19_RS02775	COG0596	Alpha beta hydrolase
AW19_RS02780	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AW19_RS02785	COG0033	Phosphoglucomutase
AW19_RS02800	COG0745	RESPONSE REGULATOR receiver
AW19_RS02805	COG2205	protein histidine kinase activity
AW19_RS02810	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AW19_RS02815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AW19_RS02820	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AW19_RS02835	COG3272	Protein of unknown function (DUF1722)
AW19_RS02845	COG5212	phosphodiesterase
AW19_RS02850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW19_RS02855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW19_RS02860	COG1984	allophanate hydrolase subunit 2
AW19_RS02865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AW19_RS02880	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AW19_RS02890	COG2009	succinate dehydrogenase
AW19_RS02895	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AW19_RS02900	COG1053	succinate dehydrogenase
AW19_RS02910	COG0567	Dehydrogenase, E1 component
AW19_RS02915	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW19_RS02925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW19_RS02930	COG0737	Belongs to the 5'-nucleotidase family
AW19_RS02935	COG1271	oxidase subunit
AW19_RS02940	COG1294	oxidase, subunit
AW19_RS02945	COG4890	Cyd operon protein YbgT
AW19_RS02950	COG3790	cyd operon protein YbgE
AW19_RS02955	COG0824	Thioesterase
AW19_RS02960	COG0811	peptide transport
AW19_RS02965	COG0848	biopolymer transport protein
AW19_RS02970	COG3064	Membrane
AW19_RS02970	COG3064	Membrane
AW19_RS02975	COG0823	Involved in the tonB-independent uptake of proteins
AW19_RS02980	COG2885	chlorophyll binding
AW19_RS02985	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AW19_RS03010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AW19_RS03020	COG1230	cation diffusion facilitator family transporter
AW19_RS03025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AW19_RS03030	COG0588	phosphoglycerate mutase activity
AW19_RS03040	COG2017	converts alpha-aldose to the beta-anomer
AW19_RS03045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AW19_RS03055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW19_RS03065	COG1119	ATPase activity
AW19_RS03070	COG3585	molybdate ion transport
AW19_RS03070	COG2005	Transcriptional regulator
AW19_RS03080	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW19_RS03085	COG4149	molybdate abc transporter
AW19_RS03095	COG0561	phosphatase activity
AW19_RS03100	COG2706	6-phosphogluconolactonase activity
AW19_RS03110	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AW19_RS03115	COG0156	8-amino-7-oxononanoate synthase activity
AW19_RS03120	COG2226	methyltransferase
AW19_RS03135	COG0556	nucleotide-excision repair
AW19_RS03140	COG4628	conserved protein (DUF2132)
AW19_RS03145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW19_RS03150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW19_RS03155	COG0315	cyclic pyranopterin monophosphate synthase activity
AW19_RS03160	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AW19_RS03165	COG0314	molybdopterin synthase activity
AW19_RS03170	COG0670	Belongs to the BI1 family
AW19_RS03175	COG0842	Transport permease protein
AW19_RS03180	COG0842	Transport permease protein
AW19_RS03185	COG1131	(ABC) transporter
AW19_RS03190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS03195	COG1309	transcriptional regulator
AW19_RS03205	COG0513	Belongs to the DEAD box helicase family
AW19_RS03210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW19_RS03220	COG2239	Acts as a magnesium transporter
AW19_RS03230	COG1686	Belongs to the peptidase S11 family
AW19_RS03235	COG0277	FAD linked oxidase domain protein
AW19_RS03255	COG2261	transglycosylase associated protein
AW19_RS03265	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AW19_RS03280	COG4807	Protein conserved in bacteria
AW19_RS03285	COG2897	thiosulfate sulfurtransferase activity
AW19_RS03300	COG1732	Glycine betaine
AW19_RS03305	COG1174	glycine betaine transport
AW19_RS03310	COG1125	glycine betaine transport
AW19_RS03315	COG1174	glycine betaine transport
AW19_RS03330	COG0697	spore germination
AW19_RS03345	COG1199	ATP-dependent helicase activity
AW19_RS03350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW19_RS03355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW19_RS03370	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AW19_RS03380	COG1126	abc transporter atp-binding protein
AW19_RS03385	COG0765	amino acid transport
AW19_RS03390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS03395	COG0783	Belongs to the Dps family
AW19_RS03400	COG4106	trans-aconitate 2-methyltransferase activity
AW19_RS03415	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AW19_RS03430	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AW19_RS03440	COG0488	(ABC) transporter
AW19_RS03445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW19_RS03450	COG0303	'Molybdopterin
AW19_RS03460	COG0477	Major facilitator Superfamily
AW19_RS03470	COG0577	efflux transmembrane transporter activity
AW19_RS03470	COG1136	(ABC) transporter
AW19_RS03500	COG0583	DNA-binding transcription factor activity
AW19_RS03505	COG0477	Major facilitator Superfamily
AW19_RS03510	COG0302	gtp cyclohydrolase
AW19_RS03515	COG2311	Membrane
AW19_RS03540	COG2116	formate transmembrane transporter activity
AW19_RS03545	COG3604	Transcriptional regulator
AW19_RS03550	COG3383	formate dehydrogenase (NAD+) activity
AW19_RS03555	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW19_RS03560	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW19_RS03570	COG3260	NADH ubiquinone oxidoreductase 20
AW19_RS03575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW19_RS03580	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AW19_RS03580	COG3261	NADH dehydrogenase
AW19_RS03585	COG0651	ATP synthesis coupled electron transport
AW19_RS03590	COG4237	Hydrogenase 4 membrane
AW19_RS03595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW19_RS03600	COG0650	Formate hydrogenlyase subunit 4
AW19_RS03605	COG0651	ATP synthesis coupled electron transport
AW19_RS03610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW19_RS03615	COG0375	protein maturation
AW19_RS03620	COG0298	carbon dioxide binding
AW19_RS03625	COG2949	membrane
AW19_RS03630	COG0281	malic enzyme
AW19_RS03640	COG1346	cytolysis
AW19_RS03645	COG1380	Effector of murein hydrolase LrgA
AW19_RS03650	COG2814	Major facilitator Superfamily
AW19_RS03670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW19_RS03670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW19_RS03675	COG0489	protein tyrosine kinase activity
AW19_RS03680	COG0572	uridine kinase
AW19_RS03685	COG0717	Belongs to the dCTP deaminase family
AW19_RS03690	COG2982	Protein involved in outer membrane biogenesis
AW19_RS03695	COG3069	C4-dicarboxylate transmembrane transporter activity
AW19_RS03700	COG1253	flavin adenine dinucleotide binding
AW19_RS03705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW19_RS03710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW19_RS03720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AW19_RS03720	COG0140	phosphoribosyl-ATP diphosphatase activity
AW19_RS03725	COG0107	imidazoleglycerol-phosphate synthase activity
AW19_RS03730	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AW19_RS03740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AW19_RS03740	COG0131	Imidazoleglycerol-phosphate dehydratase
AW19_RS03745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW19_RS03755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AW19_RS03760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW19_RS03765	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW19_RS03770	COG1129	ABC transporter
AW19_RS03775	COG0371	Dehydrogenase
AW19_RS03785	COG0531	amino acid
AW19_RS03790	COG2925	Exonuclease
AW19_RS03795	COG1022	Amp-dependent synthetase and ligase
AW19_RS03795	COG3320	Male sterility
AW19_RS03800	COG1289	transmembrane transporter activity
AW19_RS03815	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW19_RS03820	COG1129	ABC transporter
AW19_RS03835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW19_RS03840	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW19_RS03840	COG1648	precorrin-2 dehydrogenase activity
AW19_RS03845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW19_RS03865	COG4656	Part of a membrane complex involved in electron transport
AW19_RS03875	COG1012	belongs to the aldehyde dehydrogenase family
AW19_RS03885	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
AW19_RS03960	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AW19_RS03970	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AW19_RS04035	COG1492	cobalamin metabolic process
AW19_RS04050	COG0406	alpha-ribazole phosphatase activity
AW19_RS04055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AW19_RS04060	COG0583	DNA-binding transcription factor activity
AW19_RS04070	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AW19_RS04075	COG2211	Major facilitator Superfamily
AW19_RS04080	COG0137	argininosuccinate synthase activity
AW19_RS04085	COG0534	Mate efflux family protein
AW19_RS04095	COG0352	thiamine-phosphate diphosphorylase activity
AW19_RS04100	COG0561	phosphatase activity
AW19_RS04105	COG1349	DNA-binding transcription factor activity
AW19_RS04120	COG0583	DNA-binding transcription factor activity
AW19_RS04125	COG0835	chemotaxis
AW19_RS04125	COG0784	Response regulator, receiver
AW19_RS04135	COG3121	Chaperone
AW19_RS04150	COG3121	Chaperone
AW19_RS04160	COG2205	protein histidine kinase activity
AW19_RS04160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS04175	COG0251	oxidation-reduction process
AW19_RS04185	COG2977	Belongs to the P-Pant transferase superfamily
AW19_RS04200	COG2226	methyltransferase
AW19_RS04200	COG3433	isochorismatase activity
AW19_RS04200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW19_RS04225	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW19_RS04230	COG1169	isochorismate synthase
AW19_RS04240	COG4771	TonB-dependent receptor
AW19_RS04250	COG0601	transmembrane transport
AW19_RS04255	COG4171	peptide transport system, permease
AW19_RS04265	COG2375	cellular response to nickel ion
AW19_RS04265	COG1132	(ABC) transporter
AW19_RS04270	COG1132	(ABC) transporter
AW19_RS04285	COG3842	ATPase activity
AW19_RS04295	COG1840	ABC-type Fe3 transport system, periplasmic component
AW19_RS04300	COG2271	Major facilitator Superfamily
AW19_RS04315	COG4565	transcriptional regulatory protein
AW19_RS04320	COG3290	protein histidine kinase activity
AW19_RS04325	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AW19_RS04330	COG3052	prosthetic group binding
AW19_RS04335	COG2301	Belongs to the HpcH HpaI aldolase family
AW19_RS04340	COG3051	citrate lyase alpha subunit
AW19_RS04345	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AW19_RS04345	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AW19_RS04355	COG0471	metal ion transport
AW19_RS04370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AW19_RS04405	COG3228	Belongs to the MtfA family
AW19_RS04410	COG3547	Transposase (IS116 IS110 IS902 family)
AW19_RS04430	COG3121	Chaperone
AW19_RS04435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW19_RS04440	COG4589	Belongs to the CDS family
AW19_RS04450	COG2267	carboxylic ester hydrolase activity
AW19_RS04455	COG2453	phosphatase
AW19_RS04455	COG0671	phosphoesterase, PA-phosphatase related
AW19_RS04465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW19_RS04500	COG3321	synthase
AW19_RS04500	COG0604	alcohol dehydrogenase
AW19_RS04500	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS04505	COG3250	beta-galactosidase activity
AW19_RS04510	COG1609	Transcriptional regulator
AW19_RS04525	COG0840	transmembrane signaling receptor activity
AW19_RS04530	COG1285	pathogenesis
AW19_RS04540	COG0589	response to stress
AW19_RS04560	COG1360	Flagellar Motor Protein
AW19_RS04565	COG0643	Histidine kinase
AW19_RS04565	COG2198	Histidine kinase
AW19_RS04570	COG0835	chemotaxis
AW19_RS04575	COG0840	transmembrane signaling receptor activity
AW19_RS04580	COG0840	transmembrane signaling receptor activity
AW19_RS04585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW19_RS04595	COG0745	RESPONSE REGULATOR receiver
AW19_RS04600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AW19_RS04605	COG1404	Belongs to the peptidase S8 family
AW19_RS04605	COG4935	Belongs to the peptidase S8 family
AW19_RS04610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW19_RS04615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW19_RS04625	COG3418	PFAM FlgN family protein
AW19_RS04630	COG2747	anti-sigma28 factor FlgM
AW19_RS04640	COG1815	bacterial-type flagellum-dependent cell motility
AW19_RS04645	COG1558	bacterial-type flagellum-dependent cell motility
AW19_RS04650	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AW19_RS04685	COG1256	bacterial-type flagellum assembly
AW19_RS04690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW19_RS04705	COG1338	Plays a role in the flagellum-specific transport system
AW19_RS04725	COG1580	Controls the rotational direction of flagella during chemotaxis
AW19_RS04745	COG1317	bacterial-type flagellum organization
AW19_RS04760	COG1677	Flagellar hook-basal body complex protein FliE
AW19_RS04770	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW19_RS04775	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AW19_RS04805	COG1191	sigma factor activity
AW19_RS04815	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AW19_RS04820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS04825	COG0765	amino acid transport
AW19_RS04830	COG1126	abc transporter atp-binding protein
AW19_RS04845	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AW19_RS04845	COG0506	proline dehydrogenase activity
AW19_RS04845	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AW19_RS04860	COG0672	)-iron permease
AW19_RS04875	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW19_RS04880	COG0477	Major facilitator Superfamily
AW19_RS04890	COG3423	Transcriptional regulator
AW19_RS04900	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
AW19_RS04905	COG1113	amino acid transport
AW19_RS04935	COG2246	polysaccharide biosynthetic process
AW19_RS04955	COG0366	Alpha amylase catalytic
AW19_RS04975	COG2197	response regulator
AW19_RS04980	COG0322	excinuclease ABC activity
AW19_RS04985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW19_RS05025	COG3493	citrate carrier protein
AW19_RS05030	COG4565	transcriptional regulatory protein
AW19_RS05035	COG3290	protein histidine kinase activity
AW19_RS05040	COG1349	DNA-binding transcription factor activity
AW19_RS05045	COG3395	kinase activity
AW19_RS05050	COG0235	Class ii aldolase
AW19_RS05055	COG3622	Belongs to the hyi family
AW19_RS05060	COG2066	Belongs to the glutaminase family
AW19_RS05080	COG0672	)-iron permease
AW19_RS05095	COG0577	efflux transmembrane transporter activity
AW19_RS05095	COG1136	(ABC) transporter
AW19_RS05105	COG0577	efflux transmembrane transporter activity
AW19_RS05105	COG1136	(ABC) transporter
AW19_RS05130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW19_RS05135	COG4114	ferric iron reductase
AW19_RS05140	COG0006	proline dipeptidase activity
AW19_RS05145	COG0457	Tetratricopeptide repeat
AW19_RS05150	COG1649	PFAM Uncharacterised BCR, COG1649
AW19_RS05150	COG0726	polysaccharide deacetylase
AW19_RS05155	COG1215	transferase activity, transferring glycosyl groups
AW19_RS05160	COG3658	cytochrome
AW19_RS05175	COG1702	phosphate starvation-inducible protein PhoH
AW19_RS05180	COG0387	Pfam Sodium calcium exchanger
AW19_RS05190	COG0583	DNA-binding transcription factor activity
AW19_RS05195	COG3850	Histidine kinase
AW19_RS05200	COG1294	oxidase, subunit
AW19_RS05205	COG1271	oxidase subunit
AW19_RS05210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW19_RS05215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW19_RS05220	COG3138	arginine N-succinyltransferase
AW19_RS05230	COG3724	N-succinylarginine dihydrolase activity
AW19_RS05235	COG2988	succinylglutamate desuccinylase activity
AW19_RS05250	COG1228	amidohydrolase
AW19_RS05260	COG0402	S-adenosylhomocysteine deaminase activity
AW19_RS05275	COG1129	ABC transporter
AW19_RS05280	COG4211	Belongs to the binding-protein-dependent transport system permease family
AW19_RS05285	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW19_RS05295	COG4942	peptidase
AW19_RS05305	COG0012	GTP binding
AW19_RS05315	COG0193	aminoacyl-tRNA hydrolase activity
AW19_RS05325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AW19_RS05335	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AW19_RS05340	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AW19_RS05345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AW19_RS05350	COG2890	protein-(glutamine-N5) methyltransferase activity
AW19_RS05365	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AW19_RS05370	COG0659	secondary active sulfate transmembrane transporter activity
AW19_RS05395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW19_RS05400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW19_RS05405	COG3381	protein complex oligomerization
AW19_RS05415	COG0477	Major facilitator Superfamily
AW19_RS05420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW19_RS05430	COG0673	inositol 2-dehydrogenase activity
AW19_RS05435	COG0728	peptidoglycan biosynthetic process
AW19_RS05440	COG0018	arginyl-trna synthetase
AW19_RS05445	COG3102	Protein conserved in bacteria
AW19_RS05450	COG3142	Participates in the control of copper homeostasis
AW19_RS05455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW19_RS05460	COG2226	methyltransferase
AW19_RS05465	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AW19_RS05470	COG1801	Protein of unknown function DUF72
AW19_RS05475	COG1335	isochorismatase
AW19_RS05480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AW19_RS05485	COG0494	nUDIX hydrolase
AW19_RS05490	COG0217	transcriptional regulatory protein
AW19_RS05495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AW19_RS05500	COG0632	four-way junction helicase activity
AW19_RS05505	COG2255	four-way junction helicase activity
AW19_RS05510	COG3104	oligopeptide transport
AW19_RS05515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW19_RS05520	COG1121	(ABC) transporter
AW19_RS05525	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AW19_RS05530	COG0739	heme binding
AW19_RS05535	COG1560	Kdo2-lipid A biosynthetic process
AW19_RS05540	COG0469	pyruvate kinase activity
AW19_RS05545	COG1737	Transcriptional regulator
AW19_RS05550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW19_RS05555	COG0800	Aldolase
AW19_RS05560	COG2076	Multidrug Resistance protein
AW19_RS05565	COG2076	Multidrug Resistance protein
AW19_RS05570	COG0251	oxidation-reduction process
AW19_RS05575	COG1199	ATP-dependent helicase activity
AW19_RS05585	COG3065	identical protein binding
AW19_RS05590	COG0318	PFAM AMP-dependent synthetase and ligase
AW19_RS05595	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AW19_RS05600	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AW19_RS05605	COG2894	cell division
AW19_RS05610	COG0850	regulation of cytokinetic process
AW19_RS05620	COG3100	YcgL domain-containing protein
AW19_RS05625	COG2951	lytic endotransglycosylase activity
AW19_RS05630	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW19_RS05635	COG2983	Belongs to the UPF0260 family
AW19_RS05650	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW19_RS05655	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AW19_RS05660	COG2186	Transcriptional regulator
AW19_RS05665	COG2719	SpoVR family
AW19_RS05670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW19_RS05675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW19_RS05680	COG2814	Major facilitator Superfamily
AW19_RS05685	COG2202	Pas domain
AW19_RS05685	COG2199	diguanylate cyclase activity
AW19_RS05685	COG2200	EAL domain
AW19_RS05695	COG0583	DNA-binding transcription factor activity
AW19_RS05705	COG2718	Belongs to the UPF0229 family
AW19_RS05710	COG2766	serine protein kinase
AW19_RS05715	COG3713	MltA-interacting MipA family protein
AW19_RS05730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW19_RS05735	COG3139	Protein of unknown function (DUF1315)
AW19_RS05740	COG1335	isochorismatase
AW19_RS05745	COG0252	asparaginase activity
AW19_RS05750	COG0616	signal peptide processing
AW19_RS05755	COG0778	Nitroreductase
AW19_RS05765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW19_RS05775	COG0494	nUDIX hydrolase
AW19_RS05780	COG0708	Exodeoxyribonuclease III
AW19_RS05785	COG0583	DNA-binding transcription factor activity
AW19_RS05800	COG0788	formyltetrahydrofolate deformylase activity
AW19_RS05805	COG3012	SEC-C Motif Domain Protein
AW19_RS05815	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW19_RS05820	COG0745	RESPONSE REGULATOR receiver
AW19_RS05830	COG2916	Histone family protein nucleoid-structuring protein H-NS
AW19_RS05855	COG1454	alcohol dehydrogenase
AW19_RS05855	COG1012	belongs to the aldehyde dehydrogenase family
AW19_RS05860	COG2095	MarC family integral membrane protein
AW19_RS05880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW19_RS05885	COG0444	Belongs to the ABC transporter superfamily
AW19_RS05890	COG4608	Belongs to the ABC transporter superfamily
AW19_RS05895	COG3099	Belongs to the UPF0263 family
AW19_RS05900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW19_RS05905	COG2200	EAL domain
AW19_RS05920	COG2350	Protein conserved in bacteria
AW19_RS05925	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AW19_RS05935	COG2917	probably involved in intracellular septation
AW19_RS05950	COG3047	cAMP biosynthetic process
AW19_RS05960	COG0159	tryptophan synthase activity
AW19_RS05965	COG0133	tryptophan synthase activity
AW19_RS05970	COG0134	indole-3-glycerol-phosphate synthase activity
AW19_RS05970	COG0135	phosphoribosylanthranilate isomerase activity
AW19_RS05980	COG0512	Glutamine amidotransferase of anthranilate synthase
AW19_RS05985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW19_RS05990	COG0613	PHP domain protein
AW19_RS05995	COG0009	L-threonylcarbamoyladenylate synthase
AW19_RS06085	COG1187	pseudouridine synthase activity
AW19_RS06095	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AW19_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS06105	COG0616	signal peptide processing
AW19_RS06120	COG0583	DNA-binding transcription factor activity
AW19_RS06145	COG0671	phosphoesterase, PA-phosphatase related
AW19_RS06150	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AW19_RS06155	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AW19_RS06170	COG0284	orotidine-5'-phosphate decarboxylase activity
AW19_RS06175	COG0023	Translation Initiation Factor
AW19_RS06185	COG0235	Class ii aldolase
AW19_RS06195	COG1349	DNA-binding transcription factor activity
AW19_RS06200	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW19_RS06205	COG2879	small protein
AW19_RS06210	COG1966	Carbon starvation protein
AW19_RS06215	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AW19_RS06220	COG0243	molybdopterin cofactor binding
AW19_RS06240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW19_RS06250	COG4659	FMN binding
AW19_RS06255	COG4658	electron transport chain
AW19_RS06260	COG2207	Transcriptional regulator
AW19_RS06260	COG3708	Transcriptional regulator
AW19_RS06265	COG4656	Part of a membrane complex involved in electron transport
AW19_RS06285	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AW19_RS06305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AW19_RS06310	COG2160	L-arabinose isomerase activity
AW19_RS06340	COG0673	inositol 2-dehydrogenase activity
AW19_RS06345	COG0385	Bile acid
AW19_RS06350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AW19_RS06355	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW19_RS06360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS06360	COG1263	PTS System
AW19_RS06370	COG1609	Transcriptional regulator
AW19_RS06385	COG5339	Protein conserved in bacteria
AW19_RS06395	COG0114	fumarate hydratase activity
AW19_RS06415	COG2814	Major facilitator Superfamily
AW19_RS06420	COG0583	DNA-binding transcription factor activity
AW19_RS06425	COG1940	carbohydrate kinase activity
AW19_RS06430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AW19_RS06450	COG1742	UPF0060 membrane protein
AW19_RS06455	COG4221	oxidoreductase activity
AW19_RS06475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AW19_RS06480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW19_RS06490	COG1393	Belongs to the ArsC family
AW19_RS06495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW19_RS06500	COG0640	Transcriptional regulator
AW19_RS06535	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AW19_RS06550	COG0625	glutathione transferase activity
AW19_RS06555	COG3604	Transcriptional regulator
AW19_RS06560	COG1773	rubredoxin
AW19_RS06560	COG0426	domain, Protein
AW19_RS06565	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW19_RS06575	COG1522	sequence-specific DNA binding
AW19_RS06600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW19_RS06620	COG3023	N-Acetylmuramoyl-L-alanine amidase
AW19_RS06630	COG0028	Belongs to the TPP enzyme family
AW19_RS06635	COG0440	acetolactate synthase activity
AW19_RS06640	COG1011	Hydrolase
AW19_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS06665	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AW19_RS06680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW19_RS06685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW19_RS06690	COG0589	response to stress
AW19_RS06695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AW19_RS06700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AW19_RS06715	COG0531	amino acid
AW19_RS06725	COG0745	RESPONSE REGULATOR receiver
AW19_RS06730	COG2205	protein histidine kinase activity
AW19_RS06735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW19_RS06750	COG3591	Belongs to the peptidase S1B family
AW19_RS06765	COG1643	Atp-dependent helicase
AW19_RS06770	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW19_RS06775	COG3784	Protein of unknown function (DUF1318)
AW19_RS06785	COG2911	Protein conserved in bacteria
AW19_RS06790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW19_RS06795	COG3042	response to heat
AW19_RS06800	COG1285	pathogenesis
AW19_RS06810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW19_RS06810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AW19_RS06810	COG1013	pyruvate-flavodoxin oxidoreductase activity
AW19_RS06810	COG0674	pyruvate-flavodoxin oxidoreductase activity
AW19_RS06820	COG0037	tRNA processing
AW19_RS06825	COG0598	Magnesium transport protein CorA
AW19_RS06840	COG4166	transmembrane transport
AW19_RS06845	COG2866	Carboxypeptidase
AW19_RS06850	COG4948	Mandelate Racemase Muconate Lactonizing
AW19_RS06855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW19_RS06865	COG5642	Protein of unknown function (DUF2384)
AW19_RS06870	COG5654	RES domain protein
AW19_RS06875	COG3768	UPF0283 membrane protein
AW19_RS06880	COG3106	COG3106 Predicted ATPase
AW19_RS06890	COG1983	PspC domain protein
AW19_RS06900	COG1842	Phage shock protein A
AW19_RS06905	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW19_RS06920	COG4166	transmembrane transport
AW19_RS06925	COG4168	peptide transport system, permease
AW19_RS06930	COG4171	peptide transport system, permease
AW19_RS06940	COG4172	Belongs to the ABC transporter superfamily
AW19_RS06950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW19_RS06950	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW19_RS06960	COG3104	oligopeptide transport
AW19_RS06980	COG0625	glutathione transferase activity
AW19_RS06990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW19_RS07000	COG3895	Periplasmic Protein
AW19_RS07005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AW19_RS07010	COG3133	Outer membrane lipoprotein
AW19_RS07015	COG1846	Transcriptional regulator
AW19_RS07025	COG1566	PFAM secretion protein HlyD family protein
AW19_RS07030	COG1289	transmembrane transporter activity
AW19_RS07035	COG4989	oxidoreductase activity
AW19_RS07040	COG3313	Fe-S protein
AW19_RS07045	COG2194	sulfuric ester hydrolase activity
AW19_RS07050	COG1309	transcriptional regulator
AW19_RS07055	COG1902	pentaerythritol trinitrate reductase activity
AW19_RS07060	COG0346	lactoylglutathione lyase activity
AW19_RS07065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW19_RS07070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AW19_RS07075	COG0791	NLP P60 protein
AW19_RS07085	COG1609	Transcriptional regulator
AW19_RS07090	COG0583	DNA-binding transcription factor activity
AW19_RS07095	COG2814	Major facilitator Superfamily
AW19_RS07100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AW19_RS07105	COG0307	riboflavin synthase, alpha
AW19_RS07110	COG0534	Mate efflux family protein
AW19_RS07140	COG1376	ErfK ybiS ycfS ynhG family protein
AW19_RS07140	COG1388	LysM domain
AW19_RS07145	COG2166	iron-sulfur cluster assembly
AW19_RS07155	COG0719	Fe-S assembly protein
AW19_RS07160	COG0396	ATPase activity
AW19_RS07165	COG0719	Fe-S assembly protein
AW19_RS07170	COG0316	Belongs to the HesB IscA family
AW19_RS07175	COG2050	protein possibly involved in aromatic compounds catabolism
AW19_RS07180	COG0277	FAD linked oxidase domain protein
AW19_RS07180	COG0247	lactate metabolic process
AW19_RS07185	COG0628	permease
AW19_RS07190	COG0574	Belongs to the PEP-utilizing enzyme family
AW19_RS07190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW19_RS07195	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AW19_RS07215	COG3720	iron ion transport
AW19_RS07220	COG4558	Periplasmic binding protein
AW19_RS07230	COG0095	Lipoate-protein ligase
AW19_RS07235	COG0791	NLP P60 protein
AW19_RS07240	COG2076	Multidrug Resistance protein
AW19_RS07245	COG2076	Multidrug Resistance protein
AW19_RS07250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AW19_RS07255	COG0726	polysaccharide deacetylase
AW19_RS07260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW19_RS07260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW19_RS07265	COG0463	Glycosyl transferase, family 2
AW19_RS07270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW19_RS07275	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AW19_RS07280	COG0386	Belongs to the glutathione peroxidase family
AW19_RS07285	COG4139	cobalamin transport
AW19_RS07295	COG3122	Protein conserved in bacteria
AW19_RS07300	COG0776	regulation of translation
AW19_RS07320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AW19_RS07325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AW19_RS07330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW19_RS07345	COG3328	transposase activity
AW19_RS07350	COG4249	Peptidase C14 caspase catalytic subunit p20
AW19_RS07355	COG1811	Na channel or pump
AW19_RS07390	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW19_RS07395	COG1121	(ABC) transporter
AW19_RS07400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW19_RS07405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW19_RS07410	COG3001	Fructosamine kinase
AW19_RS07420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW19_RS07425	COG1917	Cupin 2, conserved barrel domain protein
AW19_RS07430	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AW19_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS07445	COG1175	transmembrane transport
AW19_RS07450	COG0395	ABC-type sugar transport system, permease component
AW19_RS07455	COG3842	ATPase activity
AW19_RS07460	COG1653	transport
AW19_RS07465	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AW19_RS07470	COG1988	membrane-bound metal-dependent
AW19_RS07475	COG1823	symporter activity
AW19_RS07480	COG3023	N-Acetylmuramoyl-L-alanine amidase
AW19_RS07490	COG0823	Involved in the tonB-independent uptake of proteins
AW19_RS07495	COG2814	Major facilitator Superfamily
AW19_RS07505	COG0501	Belongs to the peptidase M48B family
AW19_RS07510	COG0793	Belongs to the peptidase S41A family
AW19_RS07520	COG1956	GAF domain-containing protein
AW19_RS07525	COG2995	paraquat-inducible protein a
AW19_RS07530	COG3008	intermembrane lipid transfer
AW19_RS07540	COG2814	Major facilitator Superfamily
AW19_RS07575	COG2203	Gaf domain
AW19_RS07575	COG5001	Diguanylate cyclase
AW19_RS07575	COG4251	negative regulation of phosphorylation
AW19_RS07575	COG3706	GGDEF domain
AW19_RS07600	COG0668	transmembrane transport
AW19_RS07630	COG0786	glutamate:sodium symporter activity
AW19_RS07635	COG1187	pseudouridine synthase activity
AW19_RS07645	COG3077	Addiction module antitoxin, RelB DinJ family
AW19_RS07650	COG2026	Addiction module toxin, RelE StbE family
AW19_RS07665	COG1276	copper resistance
AW19_RS07670	COG2372	response to copper ion
AW19_RS07675	COG1528	Iron-storage protein
AW19_RS07690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW19_RS07695	COG1770	oligopeptidase
AW19_RS07705	COG3097	Belongs to the UPF0267 family
AW19_RS07710	COG3141	response to X-ray
AW19_RS07715	COG0513	Belongs to the DEAD box helicase family
AW19_RS07720	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AW19_RS07725	COG3140	Belongs to the UPF0181 family
AW19_RS07735	COG0494	nUDIX hydrolase
AW19_RS07740	COG1760	l-serine dehydratase
AW19_RS07745	COG1253	flavin adenine dinucleotide binding
AW19_RS07750	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS07750	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS07755	COG3715	PTS system
AW19_RS07760	COG3716	PTS system mannose fructose sorbose family IID component
AW19_RS07765	COG4811	Protein of unknown function (DUF986)
AW19_RS07770	COG1971	Probably functions as a manganese efflux pump
AW19_RS07780	COG3447	MASE1 domain protein
AW19_RS07780	COG5001	Diguanylate cyclase
AW19_RS07780	COG5002	protein histidine kinase activity
AW19_RS07790	COG2226	methyltransferase
AW19_RS07795	COG0768	penicillin binding
AW19_RS07800	COG1496	oxidoreductase activity
AW19_RS07820	COG1113	amino acid transport
AW19_RS07855	COG2207	Transcriptional regulator
AW19_RS07880	COG1132	(ABC) transporter
AW19_RS07890	COG4251	negative regulation of phosphorylation
AW19_RS07890	COG5001	Diguanylate cyclase
AW19_RS07890	COG2203	Gaf domain
AW19_RS07890	COG3706	GGDEF domain
AW19_RS07900	COG3755	Protein conserved in bacteria
AW19_RS07915	COG1733	regulation of RNA biosynthetic process
AW19_RS07920	COG0702	epimerase
AW19_RS07925	COG2873	o-acetylhomoserine
AW19_RS07935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW19_RS07940	COG0840	transmembrane signaling receptor activity
AW19_RS07965	COG0538	isocitrate dehydrogenase activity
AW19_RS07970	COG1187	pseudouridine synthase activity
AW19_RS07980	COG0482	sulfurtransferase activity
AW19_RS07985	COG2915	High frequency lysogenization protein hflD homolog
AW19_RS07990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW19_RS08000	COG0745	RESPONSE REGULATOR receiver
AW19_RS08010	COG2850	peptidyl-arginine hydroxylation
AW19_RS08025	COG1940	carbohydrate kinase activity
AW19_RS08030	COG4591	ABC-type transport system involved in lipoprotein release permease component
AW19_RS08040	COG4591	ABC-type transport system involved in lipoprotein release permease component
AW19_RS08045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW19_RS08050	COG3134	Outer membrane lipoprotein
AW19_RS08055	COG1252	NADH dehydrogenase
AW19_RS08060	COG3150	esterase
AW19_RS08065	COG1472	Belongs to the glycosyl hydrolase 3 family
AW19_RS08070	COG0510	thiamine kinase activity
AW19_RS08075	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
AW19_RS08080	COG5633	Lipoprotein
AW19_RS08085	COG0537	adenosine 5'-monophosphoramidase activity
AW19_RS08090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AW19_RS08100	COG0641	radical SAM
AW19_RS08120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS08120	COG1263	PTS System
AW19_RS08125	COG0084	hydrolase, TatD family'
AW19_RS08130	COG0470	DNA polymerase III
AW19_RS08135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AW19_RS08140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW19_RS08145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW19_RS08150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW19_RS08160	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS08165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW19_RS08175	COG0416	fatty acid biosynthetic process
AW19_RS08180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AW19_RS08185	COG1399	metal-binding, possibly nucleic acid-binding protein
AW19_RS08195	COG0564	pseudouridine synthase activity
AW19_RS08200	COG1530	ribonuclease E activity
AW19_RS08200	COG1530	ribonuclease E activity
AW19_RS08205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW19_RS08215	COG0418	dihydroorotase activity
AW19_RS08240	COG0628	permease
AW19_RS08255	COG1560	Kdo2-lipid A biosynthetic process
AW19_RS08260	COG2259	Doxx family
AW19_RS08265	COG2814	Major facilitator Superfamily
AW19_RS08285	COG5645	(Lipo)protein
AW19_RS08290	COG2943	transferase activity, transferring hexosyl groups
AW19_RS08295	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AW19_RS08310	COG3263	regulation of cellular component size
AW19_RS08325	COG4235	cytochrome complex assembly
AW19_RS08330	COG3088	subunit of a heme lyase
AW19_RS08330	COG4235	cytochrome complex assembly
AW19_RS08335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW19_RS08340	COG1138	Cytochrome C-type biogenesis protein
AW19_RS08345	COG3301	Polysulphide reductase, NrfD
AW19_RS08350	COG0437	4 iron, 4 sulfur cluster binding
AW19_RS08355	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AW19_RS08385	COG1203	CRISPR-associated helicase, Cas3
AW19_RS08390	COG1518	maintenance of DNA repeat elements
AW19_RS08400	COG2920	part of a sulfur-relay system
AW19_RS08405	COG1254	Belongs to the acylphosphatase family
AW19_RS08415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW19_RS08420	COG3785	DNA binding
AW19_RS08425	COG1832	CoA-binding protein
AW19_RS08440	COG0210	DNA helicase
AW19_RS08445	COG3304	Inner membrane component domain
AW19_RS08450	COG1289	transmembrane transporter activity
AW19_RS08455	COG3070	regulator of competence-specific genes
AW19_RS08460	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
AW19_RS08470	COG3120	sequence-specific DNA binding
AW19_RS08475	COG1067	ATP-dependent peptidase activity
AW19_RS08480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW19_RS08490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW19_RS08495	COG3009	Protein conserved in bacteria
AW19_RS08500	COG3008	intermembrane lipid transfer
AW19_RS08500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AW19_RS08505	COG2995	paraquat-inducible protein a
AW19_RS08510	COG0488	(ABC) transporter
AW19_RS08515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW19_RS08515	COG0116	Belongs to the methyltransferase superfamily
AW19_RS08520	COG3217	Mosc domain protein beta barrel domain protein
AW19_RS08520	COG0633	Ferredoxin
AW19_RS08530	COG0167	dihydroorotate dehydrogenase activity
AW19_RS08535	COG0308	aminopeptidase N
AW19_RS08540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW19_RS08545	COG0017	Asparaginyl-tRNA synthetase
AW19_RS08555	COG1448	Aminotransferase
AW19_RS08560	COG2200	EAL domain
AW19_RS08565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW19_RS08570	COG3108	Peptidase M15
AW19_RS08575	COG2989	Protein conserved in bacteria
AW19_RS08580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AW19_RS08590	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AW19_RS08595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW19_RS08600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW19_RS08605	COG3173	Aminoglycoside phosphotransferase
AW19_RS08610	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AW19_RS08615	COG2835	tetraacyldisaccharide 4'-kinase activity
AW19_RS08620	COG1278	Cold shock
AW19_RS08625	COG5383	Protein conserved in bacteria
AW19_RS08630	COG1663	tetraacyldisaccharide 4'-kinase activity
AW19_RS08640	COG0658	competence protein
AW19_RS08640	COG2333	competence protein COMEC
AW19_RS08650	COG0539	negative regulation of cytoplasmic translation
AW19_RS08655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AW19_RS08660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AW19_RS08670	COG2323	membrane
AW19_RS08675	COG0252	asparaginase activity
AW19_RS08680	COG1944	ATP diphosphatase activity
AW19_RS08685	COG2116	formate transmembrane transporter activity
AW19_RS08690	COG1882	Formate acetyltransferase
AW19_RS08695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW19_RS08700	COG2814	Major facilitator Superfamily
AW19_RS08705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AW19_RS08710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW19_RS08715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW19_RS08720	COG1674	ftsk spoiiie
AW19_RS08720	COG3107	peptidoglycan biosynthetic process
AW19_RS08725	COG1522	sequence-specific DNA binding
AW19_RS08730	COG0492	ferredoxin-NADP+ reductase activity
AW19_RS08740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW19_RS08745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AW19_RS08750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AW19_RS08755	COG0542	response to heat
AW19_RS08760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AW19_RS08765	COG1278	Cold shock
AW19_RS08775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS08780	COG2990	Protein conserved in bacteria
AW19_RS08785	COG3593	DNA synthesis involved in DNA repair
AW19_RS08790	COG2431	L-lysine efflux transmembrane transporter activity
AW19_RS08795	COG1151	hydroxylamine reductase activity
AW19_RS08800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW19_RS08805	COG0028	Belongs to the TPP enzyme family
AW19_RS08815	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AW19_RS08820	COG0702	epimerase
AW19_RS08825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW19_RS08835	COG1126	abc transporter atp-binding protein
AW19_RS08840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS08845	COG4215	(ABC) transporter
AW19_RS08850	COG4160	amino acid transport
AW19_RS08860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS08865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW19_RS08875	COG1177	transmembrane transport
AW19_RS08880	COG1176	ABC-type spermidine putrescine transport system, permease component I
AW19_RS08885	COG3842	ATPase activity
AW19_RS08890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AW19_RS08910	COG2985	domain, Protein
AW19_RS08910	COG0569	domain protein
AW19_RS08920	COG0671	phosphoesterase, PA-phosphatase related
AW19_RS08925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AW19_RS08930	COG1349	DNA-binding transcription factor activity
AW19_RS08935	COG0814	amino acid
AW19_RS08940	COG1760	l-serine dehydratase
AW19_RS08945	COG1686	Belongs to the peptidase S11 family
AW19_RS08955	COG0626	cystathionine gamma-synthase activity
AW19_RS08970	COG2011	ABC-type metal ion transport system permease component
AW19_RS08995	COG0625	glutathione transferase activity
AW19_RS09000	COG4771	TonB-dependent receptor
AW19_RS09005	COG4139	cobalamin transport
AW19_RS09010	COG0833	amino acid
AW19_RS09015	COG0583	DNA-binding transcription factor activity
AW19_RS09035	COG2855	membrane
AW19_RS09040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AW19_RS09045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW19_RS09045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW19_RS09045	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AW19_RS09050	COG1105	Belongs to the carbohydrate kinase PfkB family
AW19_RS09080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AW19_RS09090	COG0246	Mannitol dehydrogenase
AW19_RS09095	COG2186	Transcriptional regulator
AW19_RS09105	COG0523	cobalamin synthesis protein
AW19_RS09120	COG0791	NLP P60 protein
AW19_RS09130	COG2200	EAL domain
AW19_RS09135	COG4166	transmembrane transport
AW19_RS09140	COG4174	ABC transporter (Permease)
AW19_RS09145	COG4239	(ABC) transporter, permease
AW19_RS09150	COG4172	Belongs to the ABC transporter superfamily
AW19_RS09165	COG2814	Major facilitator Superfamily
AW19_RS09170	COG1187	pseudouridine synthase activity
AW19_RS09175	COG1061	Type III restriction enzyme res subunit
AW19_RS09185	COG3081	Nucleoid-associated protein
AW19_RS09190	COG3082	Protein of unknown function (DUF1414)
AW19_RS09205	COG2723	6-phospho-beta-galactosidase activity
AW19_RS09210	COG1263	PTS System
AW19_RS09210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS09210	COG2190	(PTS) system
AW19_RS09250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW19_RS09265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AW19_RS09275	COG1132	(ABC) transporter
AW19_RS09290	COG2223	nitrite transmembrane transporter activity
AW19_RS09295	COG2198	Histidine kinase
AW19_RS09295	COG0642	Histidine kinase
AW19_RS09305	COG2205	protein histidine kinase activity
AW19_RS09305	COG0784	Response regulator, receiver
AW19_RS09315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW19_RS09320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW19_RS09330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW19_RS09335	COG4574	serine-type endopeptidase inhibitor activity
AW19_RS09345	COG0814	amino acid
AW19_RS09365	COG1441	menaquinone biosynthetic process
AW19_RS09370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW19_RS09375	COG0596	Alpha beta hydrolase
AW19_RS09380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW19_RS09385	COG1169	isochorismate synthase
AW19_RS09395	COG4575	ribosome binding
AW19_RS09400	COG0129	dihydroxy-acid dehydratase activity
AW19_RS09405	COG4702	Belongs to the UPF0303 family
AW19_RS09415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW19_RS09420	COG1609	Transcriptional regulator
AW19_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS09430	COG3265	gluconokinase activity
AW19_RS09435	COG2731	YhcH YjgK YiaL family protein
AW19_RS09450	COG1007	ATP synthesis coupled electron transport
AW19_RS09455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW19_RS09460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW19_RS09465	COG0713	ATP synthesis coupled electron transport
AW19_RS09470	COG0839	Belongs to the complex I subunit 6 family
AW19_RS09475	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW19_RS09480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AW19_RS09485	COG1034	ATP synthesis coupled electron transport
AW19_RS09500	COG0649	NAD binding
AW19_RS09500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW19_RS09505	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW19_RS09515	COG0583	DNA-binding transcription factor activity
AW19_RS09520	COG0436	Aminotransferase
AW19_RS09525	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AW19_RS09530	COG0490	domain, Protein
AW19_RS09530	COG0471	metal ion transport
AW19_RS09540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW19_RS09545	COG3013	Belongs to the UPF0304 family
AW19_RS09550	COG3092	negative regulation of chromosome organization
AW19_RS09560	COG0280	phosphate acetyltransferase
AW19_RS09560	COG0857	belongs to the CobB CobQ family
AW19_RS09565	COG1609	Transcriptional regulator
AW19_RS09580	COG3037	sugar-specific permease SgaT UlaA
AW19_RS09585	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AW19_RS09590	COG0622	Phosphoesterase
AW19_RS09600	COG1090	epimerase
AW19_RS09605	COG4598	ABC transporter
AW19_RS09610	COG4160	amino acid transport
AW19_RS09615	COG4215	(ABC) transporter
AW19_RS09620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS09630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW19_RS09635	COG1286	toxin biosynthetic process
AW19_RS09640	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AW19_RS09645	COG0285	dihydrofolate synthase activity
AW19_RS09655	COG0586	Pfam SNARE associated Golgi protein
AW19_RS09665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW19_RS09670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW19_RS09675	COG2207	Transcriptional regulator
AW19_RS09680	COG0697	spore germination
AW19_RS09690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW19_RS09695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW19_RS09705	COG4232	protein-disulfide reductase activity
AW19_RS09720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW19_RS09730	COG1609	Transcriptional regulator
AW19_RS09740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW19_RS09745	COG2723	6-phospho-beta-galactosidase activity
AW19_RS09750	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW19_RS09760	COG1794	racemase activity, acting on amino acids and derivatives
AW19_RS09770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW19_RS09775	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AW19_RS09775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW19_RS09785	COG3101	peptidyl-lysine hydroxylation
AW19_RS09790	COG0730	response to heat
AW19_RS09795	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AW19_RS09800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW19_RS09805	COG2890	protein-(glutamine-N5) methyltransferase activity
AW19_RS09810	COG2840	Smr protein MutS2
AW19_RS09815	COG2062	phosphohistidine phosphatase, SixA
AW19_RS09820	COG1024	Enoyl-CoA hydratase
AW19_RS09820	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW19_RS09825	COG0183	Belongs to the thiolase family
AW19_RS09830	COG3691	Protein conserved in bacteria
AW19_RS09845	COG3088	subunit of a heme lyase
AW19_RS09845	COG4235	cytochrome complex assembly
AW19_RS09850	COG4235	cytochrome complex assembly
AW19_RS09850	COG3088	subunit of a heme lyase
AW19_RS09855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW19_RS09860	COG1138	Cytochrome C-type biogenesis protein
AW19_RS09865	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AW19_RS09870	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW19_RS09875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW19_RS09880	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW19_RS09890	COG2116	formate transmembrane transporter activity
AW19_RS09900	COG0582	viral genome integration into host DNA
AW19_RS10050	COG3728	DNA packaging
AW19_RS10070	COG3772	lysozyme
AW19_RS10210	COG3723	Recombinational DNA repair protein, rece pathway
AW19_RS10265	COG0582	viral genome integration into host DNA
AW19_RS10275	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AW19_RS10280	COG2501	S4 domain
AW19_RS10285	COG0215	cysteine-tRNA ligase activity
AW19_RS10290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW19_RS10295	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AW19_RS10300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW19_RS10305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW19_RS10310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AW19_RS10315	COG4181	ATPase activity
AW19_RS10320	COG2755	lipolytic protein G-D-S-L family
AW19_RS10325	COG0300	oxidoreductase activity
AW19_RS10330	COG3118	belongs to the thioredoxin family
AW19_RS10335	COG0330	HflC and HflK could
AW19_RS10340	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW19_RS10345	COG0789	Transcriptional regulator
AW19_RS10350	COG2217	Heavy metal translocating P-type atpase
AW19_RS10355	COG3735	TraB family
AW19_RS10360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW19_RS10365	COG0737	Belongs to the 5'-nucleotidase family
AW19_RS10370	COG2223	nitrite transmembrane transporter activity
AW19_RS10375	COG4651	solute:proton antiporter activity
AW19_RS10375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW19_RS10380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW19_RS10400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW19_RS10405	COG0438	transferase activity, transferring glycosyl groups
AW19_RS10410	COG0438	transferase activity, transferring glycosyl groups
AW19_RS10415	COG1215	transferase activity, transferring glycosyl groups
AW19_RS10420	COG1442	glycosyl transferase family 8
AW19_RS10420	COG1216	Glycosyl transferase, family 2
AW19_RS10425	COG2244	polysaccharide biosynthetic process
AW19_RS10430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AW19_RS10435	COG0563	adenylate kinase activity
AW19_RS10440	COG0326	Molecular chaperone. Has ATPase activity
AW19_RS10445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AW19_RS10450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AW19_RS10455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW19_RS10460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW19_RS10465	COG2832	Protein of unknown function (DUF454)
AW19_RS10480	COG3264	Mechanosensitive ion channel
AW19_RS10480	COG1196	nuclear chromosome segregation
AW19_RS10485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AW19_RS10490	COG1309	transcriptional regulator
AW19_RS10495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS10500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW19_RS10510	COG3457	Alanine racemase
AW19_RS10515	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AW19_RS10530	COG0254	rRNA binding
AW19_RS10535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW19_RS10540	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW19_RS10545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW19_RS10550	COG1121	(ABC) transporter
AW19_RS10570	COG3695	enzyme binding
AW19_RS10575	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AW19_RS10580	COG1946	Acyl-CoA thioesterase
AW19_RS10585	COG0004	ammonium transporteR
AW19_RS10590	COG0347	Belongs to the P(II) protein family
AW19_RS10595	COG1132	(ABC) transporter
AW19_RS10600	COG1132	(ABC) transporter
AW19_RS10605	COG1522	sequence-specific DNA binding
AW19_RS10615	COG0561	phosphatase activity
AW19_RS10620	COG4533	DNA binding
AW19_RS10625	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AW19_RS10630	COG0824	Thioesterase
AW19_RS10635	COG1555	photosystem II stabilization
AW19_RS10640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW19_RS10645	COG0776	regulation of translation
AW19_RS10650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AW19_RS10655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AW19_RS10665	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW19_RS10670	COG0271	Belongs to the BolA IbaG family
AW19_RS10675	COG3056	Lipoprotein
AW19_RS10680	COG2223	nitrite transmembrane transporter activity
AW19_RS10690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW19_RS10695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW19_RS10700	COG1845	cytochrome c oxidase, subunit III
AW19_RS10705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AW19_RS10710	COG0109	protoheme IX farnesyltransferase activity
AW19_RS10715	COG2814	Major facilitator Superfamily
AW19_RS10720	COG1666	GTP binding
AW19_RS10725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW19_RS10735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW19_RS10735	COG0301	tRNA thio-modification
AW19_RS10740	COG1722	exodeoxyribonuclease VII activity
AW19_RS10745	COG0142	geranyltranstransferase activity
AW19_RS10750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AW19_RS10755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW19_RS10760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AW19_RS10765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW19_RS10770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AW19_RS10775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW19_RS10775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW19_RS10790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW19_RS10795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW19_RS10800	COG1862	Preprotein translocase
AW19_RS10805	COG0343	queuine tRNA-ribosyltransferase activity
AW19_RS10835	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AW19_RS10840	COG0450	alkyl hydroperoxide reductase
AW19_RS10855	COG0366	Alpha amylase catalytic
AW19_RS10875	COG5002	protein histidine kinase activity
AW19_RS10880	COG0745	RESPONSE REGULATOR receiver
AW19_RS10885	COG0420	3'-5' exonuclease activity
AW19_RS10890	COG0419	ATPase involved in DNA repair
AW19_RS10895	COG1940	carbohydrate kinase activity
AW19_RS10900	COG2974	May be involved in recombination
AW19_RS10905	COG3123	guanosine phosphorylase activity
AW19_RS10910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AW19_RS10930	COG2226	methyltransferase
AW19_RS10945	COG3459	Glycosyltransferase 36 associated
AW19_RS10965	COG2188	Transcriptional regulator
AW19_RS10970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW19_RS10975	COG2313	pseudouridylate synthase activity
AW19_RS10980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW19_RS10985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AW19_RS10990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW19_RS11000	COG1073	alpha beta
AW19_RS11005	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AW19_RS11015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AW19_RS11030	COG0438	transferase activity, transferring glycosyl groups
AW19_RS11055	COG1086	Polysaccharide biosynthesis protein
AW19_RS11075	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AW19_RS11080	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW19_RS11085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW19_RS11100	COG2964	Protein conserved in bacteria
AW19_RS11115	COG2991	Protein conserved in bacteria
AW19_RS11120	COG1477	protein flavinylation
AW19_RS11125	COG2871	sodium ion transport
AW19_RS11130	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AW19_RS11135	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AW19_RS11140	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AW19_RS11145	COG1805	sodium ion transport
AW19_RS11150	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AW19_RS11155	COG3034	peptidoglycan biosynthetic process
AW19_RS11160	COG0121	glutamine amidotransferase
AW19_RS11165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AW19_RS11170	COG1960	acyl-CoA dehydrogenase activity
AW19_RS11175	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AW19_RS11180	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AW19_RS11185	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW19_RS11190	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AW19_RS11195	COG0235	Class ii aldolase
AW19_RS11200	COG0436	Aminotransferase
AW19_RS11210	COG2814	Major facilitator Superfamily
AW19_RS11215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AW19_RS11225	COG1846	Transcriptional regulator
AW19_RS11230	COG1566	PFAM secretion protein HlyD family protein
AW19_RS11235	COG2814	Major facilitator Superfamily
AW19_RS11240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW19_RS11245	COG3118	belongs to the thioredoxin family
AW19_RS11250	COG3148	PFAM DTW domain containing protein
AW19_RS11255	COG0045	succinate-CoA ligase (ADP-forming) activity
AW19_RS11255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW19_RS11255	COG1042	CoA-binding domain protein
AW19_RS11260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW19_RS11265	COG5544	Lipoprotein
AW19_RS11295	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AW19_RS11305	COG2011	ABC-type metal ion transport system permease component
AW19_RS11310	COG1464	Belongs to the NlpA lipoprotein family
AW19_RS11320	COG1720	tRNA m6t6A37 methyltransferase activity
AW19_RS11325	COG0442	prolyl-tRNA aminoacylation
AW19_RS11330	COG3015	lipoprotein NlpE involved in copper resistance
AW19_RS11340	COG4681	YaeQ
AW19_RS11350	COG4568	rho-dependent transcription termination
AW19_RS11365	COG0346	lactoylglutathione lyase activity
AW19_RS11380	COG0825	malonyl-CoA metabolic process
AW19_RS11385	COG0587	DNA-directed DNA polymerase activity
AW19_RS11390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AW19_RS11400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AW19_RS11405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW19_RS11410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AW19_RS11415	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AW19_RS11425	COG0750	zinc metalloprotease
AW19_RS11430	COG0575	Belongs to the CDS family
AW19_RS11440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW19_RS11445	COG0233	cytoplasmic translational termination
AW19_RS11450	COG0528	UMP kinase activity
AW19_RS11455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AW19_RS11460	COG0052	Belongs to the universal ribosomal protein uS2 family
AW19_RS11470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AW19_RS11475	COG2171	N-acyltransferase activity
AW19_RS11490	COG0564	pseudouridine synthase activity
AW19_RS11495	COG3098	single-species biofilm formation
AW19_RS11505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AW19_RS11505	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AW19_RS11510	COG1611	Belongs to the LOG family
AW19_RS11515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW19_RS11520	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AW19_RS11525	COG2363	Small membrane protein
AW19_RS11530	COG0583	DNA-binding transcription factor activity
AW19_RS11540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW19_RS11545	COG2166	iron-sulfur cluster assembly
AW19_RS11550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW19_RS11555	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AW19_RS11575	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW19_RS11580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AW19_RS11580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AW19_RS11585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW19_RS11590	COG1074	ATP-dependent DNA helicase activity
AW19_RS11595	COG1025	Belongs to the peptidase M16 family
AW19_RS11600	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AW19_RS11605	COG4967	type IV pilus modification protein PilV
AW19_RS11625	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AW19_RS11630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AW19_RS11640	COG1051	belongs to the nudix hydrolase family
AW19_RS11650	COG3066	DNA modification
AW19_RS11655	COG0861	Integral membrane protein TerC family
AW19_RS11660	COG0667	Aldo Keto reductase
AW19_RS11665	COG0477	Major facilitator Superfamily
AW19_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
AW19_RS11670	COG0204	Acyl-transferase
AW19_RS11680	COG1609	Transcriptional regulator
AW19_RS11690	COG0583	DNA-binding transcription factor activity
AW19_RS11695	COG2814	Major facilitator Superfamily
AW19_RS11700	COG0583	DNA-binding transcription factor activity
AW19_RS11735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW19_RS11765	COG2165	general secretion pathway protein
AW19_RS11775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW19_RS11795	COG0288	reversible hydration of carbon dioxide
AW19_RS11800	COG1733	regulation of RNA biosynthetic process
AW19_RS11805	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS11815	COG0484	heat shock protein binding
AW19_RS11820	COG1609	Transcriptional regulator
AW19_RS11825	COG2271	Major facilitator Superfamily
AW19_RS11840	COG1522	sequence-specific DNA binding
AW19_RS11935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW19_RS11945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AW19_RS11950	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW19_RS11955	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW19_RS11960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW19_RS11965	COG4974	Belongs to the 'phage' integrase family
AW19_RS11970	COG0716	FMN binding
AW19_RS11975	COG4452	Inner membrane protein CreD
AW19_RS11980	COG2205	protein histidine kinase activity
AW19_RS11985	COG0745	RESPONSE REGULATOR receiver
AW19_RS12000	COG0354	folic acid binding
AW19_RS12005	COG1272	protein, Hemolysin III
AW19_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS12020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AW19_RS12020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AW19_RS12025	COG0509	glycine decarboxylation via glycine cleavage system
AW19_RS12030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AW19_RS12035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW19_RS12040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW19_RS12045	COG0006	proline dipeptidase activity
AW19_RS12050	COG3079	Belongs to the UPF0149 family
AW19_RS12055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AW19_RS12060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW19_RS12065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW19_RS12070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AW19_RS12075	COG0583	DNA-binding transcription factor activity
AW19_RS12085	COG1279	arginine transmembrane transporter activity
AW19_RS12100	COG0191	fructose-bisphosphate aldolase activity
AW19_RS12105	COG0126	phosphoglycerate kinase activity
AW19_RS12110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW19_RS12115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AW19_RS12120	COG0501	Belongs to the peptidase M48B family
AW19_RS12130	COG1166	arginine decarboxylase activity
AW19_RS12140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AW19_RS12160	COG0640	Transcriptional regulator
AW19_RS12165	COG3091	SprT-like family
AW19_RS12170	COG2356	endonuclease I
AW19_RS12175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW19_RS12180	COG0189	ligase activity
AW19_RS12185	COG1678	Uncharacterized ACR, COG1678
AW19_RS12190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AW19_RS12195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW19_RS12205	COG2805	Type II/IV secretion system protein
AW19_RS12210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW19_RS12215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW19_RS12220	COG0762	integral membrane protein
AW19_RS12225	COG1872	DUF167
AW19_RS12230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AW19_RS12235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW19_RS12250	COG3171	Protein conserved in bacteria
AW19_RS12255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AW19_RS12260	COG1194	a g-specific adenine glycosylase
AW19_RS12265	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AW19_RS12270	COG0741	lytic transglycosylase activity
AW19_RS12280	COG1982	Orn Lys Arg decarboxylase major
AW19_RS12290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AW19_RS12320	COG0582	viral genome integration into host DNA
AW19_RS12340	COG0210	DNA helicase
AW19_RS12420	COG3675	Pfam Lipase (class 3)
AW19_RS12435	COG3501	Rhs element vgr protein
AW19_RS12460	COG3047	cAMP biosynthetic process
AW19_RS12460	COG2885	chlorophyll binding
AW19_RS12490	COG2040	homocysteine
AW19_RS12540	COG2211	Major facilitator Superfamily
AW19_RS12570	COG0656	L-ascorbic acid biosynthetic process
AW19_RS12575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW19_RS12585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW19_RS12590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW19_RS12630	COG3501	Rhs element vgr protein
AW19_RS12735	COG3179	chitinase
AW19_RS12755	COG2885	chlorophyll binding
AW19_RS12790	COG1289	transmembrane transporter activity
AW19_RS12820	COG4604	ABC transporter, ATP-binding protein
AW19_RS12825	COG4605	iron ion homeostasis
AW19_RS12835	COG4607	ABC-type enterochelin transport system periplasmic component
AW19_RS12850	COG0477	Major facilitator Superfamily
AW19_RS12865	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW19_RS12870	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW19_RS12875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AW19_RS12900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS12905	COG5001	Diguanylate cyclase
AW19_RS12915	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AW19_RS12920	COG0309	Hydrogenase expression formation protein (HypE)
AW19_RS12925	COG0409	Hydrogenase expression formation protein
AW19_RS12930	COG0298	carbon dioxide binding
AW19_RS12935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AW19_RS12945	COG1773	rubredoxin
AW19_RS12950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AW19_RS12955	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AW19_RS12960	COG5557	Pfam Polysulphide reductase, NrfD
AW19_RS12965	COG0437	4 iron, 4 sulfur cluster binding
AW19_RS12970	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AW19_RS12975	COG3133	Outer membrane lipoprotein
AW19_RS12985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW19_RS12990	COG1191	sigma factor activity
AW19_RS13010	COG1516	flagellar protein fliS
AW19_RS13015	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AW19_RS13020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW19_RS13025	COG3710	Transcriptional regulator
AW19_RS13040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW19_RS13055	COG1706	bacterial-type flagellum-dependent cell motility
AW19_RS13065	COG4786	Flagellar basal body rod
AW19_RS13080	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AW19_RS13085	COG1558	bacterial-type flagellum-dependent cell motility
AW19_RS13090	COG1815	bacterial-type flagellum-dependent cell motility
AW19_RS13135	COG1677	Flagellar hook-basal body complex protein FliE
AW19_RS13160	COG1987	bacterial-type flagellum assembly
AW19_RS13170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW19_RS13185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW19_RS13190	COG2271	Major facilitator Superfamily
AW19_RS13195	COG1028	Short-chain dehydrogenase reductase Sdr
AW19_RS13200	COG3433	isochorismatase activity
AW19_RS13200	COG1535	isochorismatase
AW19_RS13205	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW19_RS13210	COG1169	isochorismate synthase
AW19_RS13215	COG4592	Periplasmic binding protein
AW19_RS13220	COG1120	ATPase activity
AW19_RS13225	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW19_RS13230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW19_RS13240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW19_RS13255	COG4774	siderophore transport
AW19_RS13275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS13280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW19_RS13310	COG4964	Belongs to the GSP D family
AW19_RS13360	COG0848	biopolymer transport protein
AW19_RS13375	COG0586	Pfam SNARE associated Golgi protein
AW19_RS13380	COG2207	Transcriptional regulator
AW19_RS13385	COG1979	alcohol dehydrogenase
AW19_RS13390	COG0656	L-ascorbic acid biosynthetic process
AW19_RS13400	COG2132	Multicopper oxidase
AW19_RS13415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW19_RS13420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW19_RS13425	COG0583	DNA-binding transcription factor activity
AW19_RS13435	COG3150	esterase
AW19_RS13440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AW19_RS13445	COG3151	Protein conserved in bacteria
AW19_RS13450	COG0494	nUDIX hydrolase
AW19_RS13455	COG1538	Outer membrane efflux protein
AW19_RS13460	COG5463	Belongs to the UPF0441 family
AW19_RS13465	COG0754	glutathionylspermidine amidase activity
AW19_RS13470	COG3384	dioxygenase
AW19_RS13475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AW19_RS13485	COG0531	amino acid
AW19_RS13490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AW19_RS13490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AW19_RS13495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AW19_RS13500	COG3025	triphosphatase activity
AW19_RS13505	COG4991	sh3 domain protein
AW19_RS13510	COG0617	tRNA 3'-terminal CCA addition
AW19_RS13515	COG1968	undecaprenyl-diphosphatase activity
AW19_RS13520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW19_RS13525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW19_RS13530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AW19_RS13535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AW19_RS13540	COG0358	DNA primase activity
AW19_RS13555	COG3876	Protein conserved in bacteria
AW19_RS13565	COG1472	Belongs to the glycosyl hydrolase 3 family
AW19_RS13575	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AW19_RS13580	COG1263	PTS System
AW19_RS13580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS13590	COG0531	amino acid
AW19_RS13595	COG0076	glutamate decarboxylase activity
AW19_RS13605	COG3247	response to pH
AW19_RS13615	COG1902	pentaerythritol trinitrate reductase activity
AW19_RS13615	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW19_RS13620	COG2813	Specifically methylates the guanine in position
AW19_RS13630	COG1451	nucleotide metabolic process
AW19_RS13635	COG0673	inositol 2-dehydrogenase activity
AW19_RS13640	COG0861	Integral membrane protein TerC family
AW19_RS13645	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AW19_RS13655	COG2721	sulfolactate sulfo-lyase activity
AW19_RS13660	COG0246	Mannitol dehydrogenase
AW19_RS13665	COG1904	glucuronate isomerase
AW19_RS13670	COG2271	Major facilitator Superfamily
AW19_RS13685	COG0586	Pfam SNARE associated Golgi protein
AW19_RS13700	COG4575	ribosome binding
AW19_RS13705	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AW19_RS13715	COG2259	Doxx family
AW19_RS13720	COG0435	Glutathione S-transferase
AW19_RS13725	COG0583	DNA-binding transcription factor activity
AW19_RS13730	COG1741	Belongs to the pirin family
AW19_RS13735	COG1064	alcohol dehydrogenase
AW19_RS13740	COG4221	oxidoreductase activity
AW19_RS13750	COG0667	Aldo Keto reductase
AW19_RS13830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW19_RS13840	COG0792	nuclease activity
AW19_RS13845	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AW19_RS13850	COG2823	Periplasmic or secreted lipoprotein
AW19_RS13855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW19_RS13860	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AW19_RS13865	COG2198	Histidine kinase
AW19_RS13865	COG0784	Response regulator, receiver
AW19_RS13865	COG5002	protein histidine kinase activity
AW19_RS13870	COG1242	4 iron, 4 sulfur cluster binding
AW19_RS13875	COG0069	glutamate synthase activity
AW19_RS13875	COG0070	glutamate synthase
AW19_RS13875	COG0067	glutamate synthase
AW19_RS13880	COG0493	'glutamate synthase
AW19_RS13890	COG2969	positive regulation of protein catabolic process
AW19_RS13895	COG0625	glutathione transferase activity
AW19_RS13900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AW19_RS13905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AW19_RS13910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AW19_RS13915	COG3105	Protein conserved in bacteria
AW19_RS13920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW19_RS13925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW19_RS13930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AW19_RS13935	COG5007	Belongs to the BolA IbaG family
AW19_RS13940	COG3113	response to antibiotic
AW19_RS13945	COG2854	intermembrane phospholipid transfer
AW19_RS13950	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AW19_RS13955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AW19_RS13960	COG1127	ABC transporter
AW19_RS13965	COG0530	calcium, potassium:sodium antiporter activity
AW19_RS13970	COG0517	IMP dehydrogenase activity
AW19_RS13970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AW19_RS13975	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AW19_RS13980	COG3117	lipopolysaccharide transmembrane transporter activity
AW19_RS13985	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AW19_RS13990	COG1137	ATPase activity
AW19_RS13995	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW19_RS14010	COG1660	Displays ATPase and GTPase activities
AW19_RS14015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS14020	COG0540	Belongs to the ATCase OTCase family
AW19_RS14025	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AW19_RS14035	COG0366	Alpha amylase catalytic
AW19_RS14040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW19_RS14040	COG1263	PTS System
AW19_RS14050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW19_RS14055	COG3711	transcriptional antiterminator
AW19_RS14055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS14060	COG2706	6-phosphogluconolactonase activity
AW19_RS14075	COG3964	amidohydrolase
AW19_RS14105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AW19_RS14110	COG3783	Cytochrome b(562)
AW19_RS14115	COG0312	modulator of DNA gyrase
AW19_RS14120	COG3028	Belongs to the UPF0307 family
AW19_RS14125	COG2732	(Barnase) inhibitor
AW19_RS14140	COG1289	transmembrane transporter activity
AW19_RS14145	COG1566	PFAM secretion protein HlyD family protein
AW19_RS14155	COG0583	DNA-binding transcription factor activity
AW19_RS14160	COG0312	modulator of DNA gyrase
AW19_RS14165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW19_RS14170	COG3164	Protein of unknown function
AW19_RS14175	COG1530	ribonuclease E activity
AW19_RS14180	COG0424	maF-like protein
AW19_RS14185	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AW19_RS14190	COG1792	Involved in formation and maintenance of cell shape
AW19_RS14195	COG1077	Cell shape determining protein MreB Mrl
AW19_RS14200	COG2200	EAL domain
AW19_RS14200	COG2199	diguanylate cyclase activity
AW19_RS14205	COG0604	alcohol dehydrogenase
AW19_RS14215	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AW19_RS14220	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AW19_RS14225	COG0511	ligase activity, forming carbon-carbon bonds
AW19_RS14230	COG0439	Biotin carboxylase
AW19_RS14235	COG3924	membrane
AW19_RS14240	COG4145	pantothenate transmembrane transporter activity
AW19_RS14245	COG2264	protein methyltransferase activity
AW19_RS14250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW19_RS14255	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AW19_RS14260	COG3706	GGDEF domain
AW19_RS14265	COG3133	Outer membrane lipoprotein
AW19_RS14270	COG1278	Cold shock
AW19_RS14275	COG1278	Cold shock
AW19_RS14285	COG0471	metal ion transport
AW19_RS14290	COG1560	Kdo2-lipid A biosynthetic process
AW19_RS14305	COG1380	Effector of murein hydrolase LrgA
AW19_RS14310	COG0583	DNA-binding transcription factor activity
AW19_RS14315	COG0025	NhaP-type Na H and K H
AW19_RS14320	COG2252	PERMEase
AW19_RS14345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW19_RS14350	COG2315	Protein conserved in bacteria
AW19_RS14355	COG1448	Aminotransferase
AW19_RS14385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW19_RS14390	COG0735	belongs to the Fur family
AW19_RS14395	COG3237	CsbD-like
AW19_RS14400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AW19_RS14405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW19_RS14410	COG2937	Belongs to the GPAT DAPAT family
AW19_RS14415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AW19_RS14420	COG3161	chorismate lyase activity
AW19_RS14445	COG2182	Extracellular solute-binding protein
AW19_RS14450	COG1175	transmembrane transport
AW19_RS14455	COG3833	ABC-type maltose transport systems, permease component
AW19_RS14460	COG3223	Belongs to the PsiE family
AW19_RS14470	COG0527	aspartate kinase activity
AW19_RS14495	COG1414	Transcriptional regulator
AW19_RS14500	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AW19_RS14505	COG2224	Isocitrate lyase
AW19_RS14510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AW19_RS14515	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AW19_RS14555	COG0138	bifunctional purine biosynthesis protein purh
AW19_RS14560	COG0151	Belongs to the GarS family
AW19_RS14580	COG1515	deoxyribonuclease V activity
AW19_RS14585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW19_RS14590	COG2816	NAD+ diphosphatase activity
AW19_RS14595	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AW19_RS14610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW19_RS14615	COG2104	thiamine diphosphate biosynthetic process
AW19_RS14620	COG2022	thiamine diphosphate biosynthetic process
AW19_RS14625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AW19_RS14635	COG0085	RNA polymerase activity
AW19_RS14645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AW19_RS14650	COG0081	regulation of translation
AW19_RS14655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AW19_RS14660	COG0250	Participates in transcription elongation, termination and antitermination
AW19_RS14670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AW19_RS14700	COG1072	(Pantothenic acid kinase))
AW19_RS14740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW19_RS14745	COG1739	Uncharacterized protein family UPF0029
AW19_RS14750	COG0006	proline dipeptidase activity
AW19_RS14755	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW19_RS14755	COG1024	Enoyl-CoA hydratase
AW19_RS14760	COG0183	Belongs to the thiolase family
AW19_RS14770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AW19_RS14790	COG0805	protein transport
AW19_RS14795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW19_RS14800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AW19_RS14805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AW19_RS14815	COG2226	methyltransferase
AW19_RS14820	COG1322	Protein conserved in bacteria
AW19_RS14825	COG0586	Pfam SNARE associated Golgi protein
AW19_RS14830	COG1966	Carbon starvation protein
AW19_RS14845	COG0412	Dienelactone hydrolase
AW19_RS14850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AW19_RS14855	COG0583	DNA-binding transcription factor activity
AW19_RS14860	COG0697	spore germination
AW19_RS14865	COG0679	Auxin Efflux Carrier
AW19_RS14870	COG0584	glycerophosphoryl diester phosphodiesterase
AW19_RS14875	COG3842	ATPase activity
AW19_RS14880	COG0395	ABC-type sugar transport system, permease component
AW19_RS14885	COG1175	transmembrane transport
AW19_RS14890	COG1653	transport
AW19_RS14925	COG0410	ABC transporter
AW19_RS14935	COG4177	L-phenylalanine transmembrane transporter activity
AW19_RS14945	COG0683	leucine binding
AW19_RS14970	COG2177	Part of the ABC transporter FtsEX involved in
AW19_RS14975	COG2884	Cell division ATP-binding protein ftsE
AW19_RS14980	COG0552	protein localization to endoplasmic reticulum
AW19_RS14985	COG0742	ribosomal rna small subunit methyltransferase
AW19_RS14990	COG3776	membrane
AW19_RS15005	COG3714	YhhN family
AW19_RS15015	COG0425	Belongs to the sulfur carrier protein TusA family
AW19_RS15020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AW19_RS15030	COG0247	lactate metabolic process
AW19_RS15040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW19_RS15045	COG2271	Major facilitator Superfamily
AW19_RS15050	COG0584	glycerophosphoryl diester phosphodiesterase
AW19_RS15055	COG0561	phosphatase activity
AW19_RS15060	COG2267	carboxylic ester hydrolase activity
AW19_RS15065	COG1280	lysine exporter protein (LysE YggA)
AW19_RS15070	COG1280	lysine exporter protein (LysE YggA)
AW19_RS15075	COG0514	ATP-dependent DNA helicase (RecQ)
AW19_RS15080	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AW19_RS15085	COG2050	protein possibly involved in aromatic compounds catabolism
AW19_RS15105	COG5564	TIM-barrel signal transduction protein
AW19_RS15110	COG5441	Belongs to the UPF0261 family
AW19_RS15120	COG0210	DNA helicase
AW19_RS15125	COG1011	Hydrolase
AW19_RS15130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AW19_RS15135	COG3159	Protein conserved in bacteria
AW19_RS15140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AW19_RS15145	COG5567	small periplasmic lipoprotein
AW19_RS15150	COG1965	Belongs to the frataxin family
AW19_RS15155	COG3072	Adenylate cyclase
AW19_RS15160	COG0181	hydroxymethylbilane synthase activity
AW19_RS15165	COG1587	Uroporphyrinogen-III synthase
AW19_RS15170	COG2959	enzyme of heme biosynthesis
AW19_RS15175	COG3071	HemY protein
AW19_RS15215	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AW19_RS15220	COG2244	polysaccharide biosynthetic process
AW19_RS15225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AW19_RS15230	COG0456	acetyltransferase
AW19_RS15235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW19_RS15240	COG1088	dTDP-glucose 4,6-dehydratase activity
AW19_RS15245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW19_RS15250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW19_RS15255	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AW19_RS15260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW19_RS15270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW19_RS15275	COG3118	belongs to the thioredoxin family
AW19_RS15285	COG0248	Ppx GppA phosphatase
AW19_RS15295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW19_RS15305	COG3121	Chaperone
AW19_RS15320	COG3121	Chaperone
AW19_RS15350	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW19_RS15355	COG0583	DNA-binding transcription factor activity
AW19_RS15360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW19_RS15365	COG0129	dihydroxy-acid dehydratase activity
AW19_RS15370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW19_RS15375	COG3978	acetolactate synthase activity
AW19_RS15390	COG3085	chromosome segregation
AW19_RS15395	COG0583	DNA-binding transcription factor activity
AW19_RS15435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW19_RS15445	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW19_RS15460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW19_RS15470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW19_RS15470	COG0678	peroxiredoxin activity
AW19_RS15475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW19_RS15520	COG0165	Argininosuccinate lyase
AW19_RS15525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AW19_RS15540	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AW19_RS15550	COG0460	homoserine dehydrogenase
AW19_RS15550	COG0527	aspartate kinase activity
AW19_RS15555	COG0626	cystathionine gamma-synthase activity
AW19_RS15560	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
AW19_RS15565	COG0254	rRNA binding
AW19_RS15570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW19_RS15575	COG1609	Transcriptional regulator
AW19_RS15580	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AW19_RS15585	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AW19_RS15590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AW19_RS15595	COG1575	Belongs to the MenA family. Type 1 subfamily
AW19_RS15600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AW19_RS15605	COG3074	FtsZ-dependent cytokinesis
AW19_RS15610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW19_RS15615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AW19_RS15620	COG1494	fructose-1,6-bisphosphatase
AW19_RS15625	COG2814	Major facilitator Superfamily
AW19_RS15635	COG3152	Membrane
AW19_RS15655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AW19_RS15665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW19_RS15670	COG3678	ATP-independent chaperone mediated protein folding
AW19_RS15675	COG0745	RESPONSE REGULATOR receiver
AW19_RS15680	COG2205	protein histidine kinase activity
AW19_RS15685	COG2169	Transcriptional regulator
AW19_RS15685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW19_RS15690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW19_RS15695	COG1045	serine acetyltransferase
AW19_RS15700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AW19_RS15710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AW19_RS15715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW19_RS15720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW19_RS15725	COG4942	peptidase
AW19_RS15730	COG2861	carbohydrate metabolic process
AW19_RS15740	COG1063	alcohol dehydrogenase
AW19_RS15745	COG0156	8-amino-7-oxononanoate synthase activity
AW19_RS15750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW19_RS15755	COG0859	PFAM glycosyl transferase family 9
AW19_RS15760	COG0859	PFAM glycosyl transferase family 9
AW19_RS15765	COG1519	Transferase
AW19_RS15780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AW19_RS15785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AW19_RS15790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AW19_RS15795	COG2003	Belongs to the UPF0758 family
AW19_RS15800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW19_RS15805	COG0756	dUTP diphosphatase activity
AW19_RS15810	COG1309	transcriptional regulator
AW19_RS15820	COG4974	Belongs to the 'phage' integrase family
AW19_RS15860	COG2176	DNA-directed DNA polymerase activity
AW19_RS15860	COG5002	protein histidine kinase activity
AW19_RS15905	COG4695	Portal protein
AW19_RS16055	COG1561	YicC-like family, N-terminal region
AW19_RS16080	COG5001	Diguanylate cyclase
AW19_RS16085	COG1024	Enoyl-CoA hydratase
AW19_RS16095	COG2860	membrane
AW19_RS16100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AW19_RS16110	COG1758	RNA polymerase activity
AW19_RS16115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW19_RS16120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW19_RS16125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW19_RS16130	COG0786	glutamate:sodium symporter activity
AW19_RS16135	COG2233	PERMEase
AW19_RS16140	COG2982	Protein involved in outer membrane biogenesis
AW19_RS16155	COG3423	Transcriptional regulator
AW19_RS16160	COG0456	acetyltransferase
AW19_RS16165	COG1490	D-aminoacyl-tRNA deacylase activity
AW19_RS16170	COG1295	ribonuclease BN
AW19_RS16175	COG1011	Hydrolase
AW19_RS16190	COG3852	Histidine kinase
AW19_RS16200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW19_RS16205	COG3078	GTPase activator activity
AW19_RS16210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AW19_RS16215	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW19_RS16215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW19_RS16220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW19_RS16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW19_RS16230	COG3084	Protein conserved in bacteria
AW19_RS16240	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW19_RS16270	COG2186	Transcriptional regulator
AW19_RS16275	COG0477	Major facilitator Superfamily
AW19_RS16280	COG1609	Transcriptional regulator
AW19_RS16285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW19_RS16290	COG1879	ABC-type sugar transport system periplasmic component
AW19_RS16295	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW19_RS16305	COG1869	D-ribose catabolic process
AW19_RS16310	COG3158	transport of potassium into the cell
AW19_RS16315	COG0714	Associated with various cellular activities
AW19_RS16320	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AW19_RS16330	COG2502	aspartate--ammonia ligase
AW19_RS16335	COG1522	sequence-specific DNA binding
AW19_RS16340	COG0716	FMN binding
AW19_RS16345	COG0445	tRNA wobble uridine modification
AW19_RS16350	COG0357	Ribosomal RNA small subunit methyltransferase G
AW19_RS16355	COG3312	ion transport
AW19_RS16360	COG0356	it plays a direct role in the translocation of protons across the membrane
AW19_RS16370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AW19_RS16375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AW19_RS16380	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AW19_RS16390	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AW19_RS16395	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AW19_RS16400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AW19_RS16410	COG0659	secondary active sulfate transmembrane transporter activity
AW19_RS16415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW19_RS16420	COG0573	inorganic phosphate transmembrane transporter activity
AW19_RS16425	COG0581	inorganic phosphate transmembrane transporter activity
AW19_RS16435	COG0704	Plays a role in the regulation of phosphate uptake
AW19_RS16445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS16450	COG0765	amino acid transport
AW19_RS16455	COG0765	amino acid transport
AW19_RS16460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW19_RS16465	COG2252	PERMEase
AW19_RS16475	COG4566	intracellular signal transduction
AW19_RS16480	COG4191	Histidine kinase
AW19_RS16485	COG0431	NADPH-dependent FMN reductase
AW19_RS16490	COG0840	transmembrane signaling receptor activity
AW19_RS16495	COG2011	ABC-type metal ion transport system permease component
AW19_RS16510	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AW19_RS16515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AW19_RS16520	COG0706	membrane insertase activity
AW19_RS16525	COG0594	ribonuclease P activity
AW19_RS16530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AW19_RS16535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AW19_RS16540	COG0592	DNA-directed DNA polymerase activity
AW19_RS16545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AW19_RS16550	COG0187	DNA topoisomerase II activity
AW19_RS16555	COG0561	phosphatase activity
AW19_RS16560	COG2423	ornithine cyclodeaminase activity
AW19_RS16575	COG0823	Involved in the tonB-independent uptake of proteins
AW19_RS16580	COG5645	(Lipo)protein
AW19_RS16595	COG2985	domain, Protein
AW19_RS16595	COG0569	domain protein
AW19_RS16600	COG3977	Valine--pyruvate aminotransferase
AW19_RS16605	COG0366	Alpha amylase catalytic
AW19_RS16610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW19_RS16635	COG0456	acetyltransferase
AW19_RS16640	COG2818	Glycosylase
AW19_RS16650	COG0752	glycyl-tRNA synthetase alpha subunit
AW19_RS16655	COG0751	glycine-tRNA ligase activity
AW19_RS16665	COG2213	PTS system mannitol-specific
AW19_RS16665	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS16670	COG0246	Mannitol dehydrogenase
AW19_RS16675	COG3722	fumarate hydratase activity
AW19_RS16685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW19_RS16700	COG0840	transmembrane signaling receptor activity
AW19_RS16705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW19_RS16710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW19_RS16715	COG3383	formate dehydrogenase (NAD+) activity
AW19_RS16715	COG0243	molybdopterin cofactor binding
AW19_RS16720	COG3383	formate dehydrogenase (NAD+) activity
AW19_RS16720	COG0243	molybdopterin cofactor binding
AW19_RS16725	COG0437	4 iron, 4 sulfur cluster binding
AW19_RS16730	COG2864	formate dehydrogenase
AW19_RS16735	COG3058	Necessary for formate dehydrogenase activity
AW19_RS16740	COG1921	L-seryl-tRNASec selenium transferase activity
AW19_RS16745	COG3276	selenocysteine insertion sequence binding
AW19_RS16755	COG3550	peptidyl-serine autophosphorylation
AW19_RS16765	COG3274	enterobacterial common antigen metabolic process
AW19_RS16775	COG1335	isochorismatase
AW19_RS16780	COG3121	Chaperone
AW19_RS16785	COG1070	Carbohydrate kinase
AW19_RS16790	COG2115	Belongs to the xylose isomerase family
AW19_RS16795	COG4213	ABC transporter substrate-binding protein
AW19_RS16805	COG4214	carbohydrate transport
AW19_RS16810	COG2207	Transcriptional regulator
AW19_RS16810	COG1609	Transcriptional regulator
AW19_RS16815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW19_RS16815	COG2205	protein histidine kinase activity
AW19_RS16840	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AW19_RS16845	COG2986	histidine ammonia-lyase
AW19_RS16865	COG1764	response to oxidative stress
AW19_RS16870	COG2194	sulfuric ester hydrolase activity
AW19_RS16875	COG2197	response regulator
AW19_RS16880	COG3851	Histidine kinase
AW19_RS16885	COG2271	Major facilitator Superfamily
AW19_RS16900	COG2831	hemolysin activation secretion protein
AW19_RS16905	COG3210	domain, Protein
AW19_RS16910	COG0747	negative chemotaxis
AW19_RS16915	COG0601	transmembrane transport
AW19_RS16920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW19_RS16925	COG0444	Belongs to the ABC transporter superfamily
AW19_RS16930	COG4608	Belongs to the ABC transporter superfamily
AW19_RS16935	COG2194	sulfuric ester hydrolase activity
AW19_RS16955	COG1192	Involved in chromosome partitioning
AW19_RS16960	COG1215	transferase activity, transferring glycosyl groups
AW19_RS16965	COG1215	transferase activity, transferring glycosyl groups
AW19_RS16970	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW19_RS16975	COG3118	belongs to the thioredoxin family
AW19_RS16975	COG0457	Tetratricopeptide repeat
AW19_RS16980	COG2199	diguanylate cyclase activity
AW19_RS16980	COG2200	EAL domain
AW19_RS16985	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AW19_RS16995	COG1301	dicarboxylic acid transport
AW19_RS17000	COG0612	Peptidase, M16
AW19_RS17005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW19_RS17010	COG1942	4-Oxalocrotonate Tautomerase
AW19_RS17015	COG2200	EAL domain
AW19_RS17020	COG2982	Protein involved in outer membrane biogenesis
AW19_RS17025	COG2134	cdp-diacylglycerol pyrophosphatase
AW19_RS17035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW19_RS17040	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AW19_RS17050	COG0742	ribosomal rna small subunit methyltransferase
AW19_RS17065	COG0589	response to stress
AW19_RS17075	COG0306	phosphate transporter
AW19_RS17080	COG2081	HI0933 family
AW19_RS17140	COG3718	enzyme involved in inositol metabolism
AW19_RS17150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW19_RS17155	COG3962	Belongs to the TPP enzyme family
AW19_RS17160	COG0673	inositol 2-dehydrogenase activity
AW19_RS17165	COG1082	Xylose isomerase domain protein TIM barrel
AW19_RS17170	COG1082	Xylose isomerase domain protein TIM barrel
AW19_RS17175	COG1247	-acetyltransferase
AW19_RS17180	COG1741	Belongs to the pirin family
AW19_RS17185	COG1609	Transcriptional regulator
AW19_RS17190	COG2610	gluconate transmembrane transporter activity
AW19_RS17195	COG3265	gluconokinase activity
AW19_RS17200	COG2095	MarC family integral membrane protein
AW19_RS17205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW19_RS17220	COG0463	Glycosyl transferase, family 2
AW19_RS17245	COG3275	phosphorelay sensor kinase activity
AW19_RS17250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AW19_RS17255	COG1523	belongs to the glycosyl hydrolase 13 family
AW19_RS17265	COG0297	glycogen (starch) synthase activity
AW19_RS17270	COG0058	SHG alpha-glucan phosphorylase activity
AW19_RS17275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW19_RS17285	COG1349	DNA-binding transcription factor activity
AW19_RS17290	COG0705	Rhomboid family
AW19_RS17300	COG2909	trisaccharide binding
AW19_RS17305	COG0058	SHG alpha-glucan phosphorylase activity
AW19_RS17310	COG1640	4-alpha-glucanotransferase
AW19_RS17315	COG0316	Belongs to the HesB IscA family
AW19_RS17315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW19_RS17325	COG0596	Alpha beta hydrolase
AW19_RS17340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW19_RS17345	COG1918	ferrous iron import across plasma membrane
AW19_RS17350	COG2183	response to ionizing radiation
AW19_RS17375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AW19_RS17390	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AW19_RS17400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW19_RS17405	COG1011	Hydrolase
AW19_RS17415	COG0494	nUDIX hydrolase
AW19_RS17420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AW19_RS17445	COG4796	Type ii and iii secretion system protein
AW19_RS17450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AW19_RS17470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW19_RS17480	COG0180	Tryptophanyl-tRNA synthetase
AW19_RS17485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW19_RS17485	COG1648	precorrin-2 dehydrogenase activity
AW19_RS17500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW19_RS17505	COG0402	S-adenosylhomocysteine deaminase activity
AW19_RS17510	COG0738	Major facilitator superfamily
AW19_RS17515	COG1609	Transcriptional regulator
AW19_RS17520	COG1486	melibiose metabolic process
AW19_RS17525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW19_RS17530	COG0433	COG0433 Predicted ATPase
AW19_RS17550	COG1289	transmembrane transporter activity
AW19_RS17560	COG1765	OsmC-like protein
AW19_RS17565	COG3954	Phosphoribulokinase
AW19_RS17570	COG3089	Belongs to the UPF0270 family
AW19_RS17575	COG0429	hydrolase of the alpha beta-hydrolase fold
AW19_RS17590	COG4521	taurine ABC transporter
AW19_RS17600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW19_RS17605	COG2175	clavaminate synthase activity
AW19_RS17620	COG0488	(ABC) transporter
AW19_RS17625	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW19_RS17635	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AW19_RS17640	COG1047	Peptidyl-prolyl cis-trans
AW19_RS17645	COG2900	Belongs to the SlyX family
AW19_RS17650	COG0545	Peptidyl-prolyl cis-trans isomerase
AW19_RS17655	COG2964	Protein conserved in bacteria
AW19_RS17660	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AW19_RS17665	COG2923	Belongs to the DsrF TusC family
AW19_RS17670	COG2168	tRNA wobble position uridine thiolation
AW19_RS17675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AW19_RS17680	COG0049	tRNA binding
AW19_RS17690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AW19_RS17705	COG0051	transcription antitermination factor activity, RNA binding
AW19_RS17710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AW19_RS17720	COG0089	rRNA binding
AW19_RS17725	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AW19_RS17730	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AW19_RS17735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AW19_RS17740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AW19_RS17745	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AW19_RS17750	COG0255	Belongs to the universal ribosomal protein uL29 family
AW19_RS17755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AW19_RS17760	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AW19_RS17765	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AW19_RS17775	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AW19_RS17785	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AW19_RS17790	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AW19_RS17800	COG1841	ribosomal large subunit assembly
AW19_RS17805	COG0200	Binds to the 23S rRNA
AW19_RS17810	COG0201	protein transport
AW19_RS17815	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW19_RS17820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AW19_RS17825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AW19_RS17830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AW19_RS17835	COG0202	RNA polymerase activity
AW19_RS17840	COG0203	ribosomal protein L17
AW19_RS17850	COG0789	Transcriptional regulator
AW19_RS17855	COG3036	rescue of stalled ribosome
AW19_RS17860	COG1970	mechanosensitive ion channel activity
AW19_RS17870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW19_RS17870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW19_RS17875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW19_RS17880	COG0242	peptide deformylase activity
AW19_RS17885	COG0758	DNA mediated transformation
AW19_RS17895	COG0551	DNA topoisomerase type I activity
AW19_RS17900	COG0009	L-threonylcarbamoyladenylate synthase
AW19_RS17905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AW19_RS17910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW19_RS17940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW19_RS17945	COG3162	membrane
AW19_RS17950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW19_RS17955	COG1301	dicarboxylic acid transport
AW19_RS18120	COG2391	methyltransferase activity
AW19_RS18125	COG0425	Belongs to the sulfur carrier protein TusA family
AW19_RS18130	COG3264	Mechanosensitive ion channel
AW19_RS18130	COG1511	domain protein
AW19_RS18135	COG4774	siderophore transport
AW19_RS18145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW19_RS18150	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AW19_RS18155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW19_RS18160	COG4558	Periplasmic binding protein
AW19_RS18165	COG3720	iron ion transport
AW19_RS18435	COG3657	addiction module killer protein
AW19_RS18510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AW19_RS18515	COG0210	DNA helicase
AW19_RS18525	COG2826	transposase and inactivated derivatives, IS30 family
AW19_RS18545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AW19_RS18555	COG1309	transcriptional regulator
AW19_RS18565	COG2084	Dehydrogenase
AW19_RS18570	COG1929	Belongs to the glycerate kinase type-1 family
AW19_RS18575	COG3835	regulator
AW19_RS18580	COG2721	sulfolactate sulfo-lyase activity
AW19_RS18585	COG2271	Major facilitator Superfamily
AW19_RS18590	COG0493	'glutamate synthase
AW19_RS18590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW19_RS18595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AW19_RS18600	COG3383	formate dehydrogenase (NAD+) activity
AW19_RS18605	COG4232	protein-disulfide reductase activity
AW19_RS18615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW19_RS18630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AW19_RS18635	COG0459	protein refolding
AW19_RS18650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AW19_RS18670	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AW19_RS18675	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AW19_RS18680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW19_RS18685	COG1053	succinate dehydrogenase
AW19_RS18690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AW19_RS18695	COG1511	domain protein
AW19_RS18695	COG3264	Mechanosensitive ion channel
AW19_RS18700	COG0688	phosphatidylethanolamine metabolic process
AW19_RS18705	COG1162	GTPase activity
AW19_RS18710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AW19_RS18735	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW19_RS18740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AW19_RS18740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AW19_RS18745	COG0802	atpase or kinase
AW19_RS18750	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW19_RS18755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AW19_RS18760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AW19_RS18770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW19_RS18775	COG0330	HflC and HflK could
AW19_RS18780	COG0330	HflC and HflK could
AW19_RS18785	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AW19_RS18790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AW19_RS18795	COG1959	2 iron, 2 sulfur cluster binding
AW19_RS18800	COG0557	exoribonuclease II activity
AW19_RS18805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW19_RS18810	COG1960	acyl-CoA dehydrogenase activity
AW19_RS18815	COG3650	response to hydrogen peroxide
AW19_RS18820	COG1073	alpha beta
AW19_RS18830	COG0360	Binds together with S18 to 16S ribosomal RNA
AW19_RS18835	COG2965	DNA replication, synthesis of RNA primer
AW19_RS18840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AW19_RS18845	COG0359	binds to the 23S rRNA
AW19_RS18855	COG3061	Opacity-associated protein A
AW19_RS18860	COG0545	Peptidyl-prolyl cis-trans isomerase
AW19_RS18870	COG0737	Belongs to the 5'-nucleotidase family
AW19_RS18875	COG1218	3'(2'),5'-bisphosphate nucleotidase
AW19_RS18880	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AW19_RS18890	COG1253	flavin adenine dinucleotide binding
AW19_RS18895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW19_RS18900	COG0729	surface antigen
AW19_RS18905	COG2911	Protein conserved in bacteria
AW19_RS18910	COG2105	PFAM AIG2 family protein
AW19_RS18915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AW19_RS18920	COG0840	transmembrane signaling receptor activity
AW19_RS18925	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AW19_RS18930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AW19_RS18945	COG1438	arginine binding
AW19_RS18950	COG0039	L-malate dehydrogenase activity
AW19_RS18955	COG3423	Transcriptional regulator
AW19_RS18965	COG0142	geranyltranstransferase activity
AW19_RS18980	COG0697	spore germination
AW19_RS18985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW19_RS18990	COG0642	Histidine kinase
AW19_RS18995	COG0745	RESPONSE REGULATOR receiver
AW19_RS19000	COG2027	D-alanyl-D-alanine carboxypeptidase
AW19_RS19010	COG1534	Rna-binding protein
AW19_RS19015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AW19_RS19025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW19_RS19035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW19_RS19050	COG0779	Required for maturation of 30S ribosomal subunits
AW19_RS19055	COG0195	Participates in both transcription termination and antitermination
AW19_RS19060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AW19_RS19065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AW19_RS19070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW19_RS19080	COG1185	polyribonucleotide nucleotidyltransferase activity
AW19_RS19090	COG0513	Belongs to the DEAD box helicase family
AW19_RS19095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW19_RS19100	COG0826	peptidase U32
AW19_RS19105	COG0826	peptidase U32
AW19_RS19110	COG3154	lipid carrier protein
AW19_RS19115	COG3153	acetyltransferase
AW19_RS19120	COG2827	Endonuclease containing a URI domain
AW19_RS19125	COG0531	amino acid
AW19_RS19130	COG1982	Orn Lys Arg decarboxylase major
AW19_RS19145	COG1653	transport
AW19_RS19150	COG1175	transmembrane transport
AW19_RS19155	COG0395	ABC-type sugar transport system, permease component
AW19_RS19160	COG3842	ATPase activity
AW19_RS19170	COG3787	Belongs to the UPF0306 family
AW19_RS19175	COG0702	epimerase
AW19_RS19180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW19_RS19185	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AW19_RS19190	COG3454	Phosphonate metabolism
AW19_RS19195	COG4778	phosphonate C-P lyase system protein PhnL
AW19_RS19200	COG4107	phosphonate C-P lyase system protein PhnK
AW19_RS19205	COG3627	carbon phosphorus lyase activity
AW19_RS19210	COG3626	phosphonate metabolism
AW19_RS19215	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AW19_RS19220	COG3624	Phosphonate C-P lyase system protein PhnG
AW19_RS19225	COG2188	Transcriptional regulator
AW19_RS19240	COG4608	Belongs to the ABC transporter superfamily
AW19_RS19245	COG0444	Belongs to the ABC transporter superfamily
AW19_RS19250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW19_RS19255	COG0601	transmembrane transport
AW19_RS19265	COG2731	YhcH YjgK YiaL family protein
AW19_RS19275	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AW19_RS19295	COG2927	DNA polymerase III (CHI subunit)
AW19_RS19300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AW19_RS19305	COG0795	lipopolysaccharide-transporting ATPase activity
AW19_RS19310	COG0795	lipopolysaccharide-transporting ATPase activity
AW19_RS19325	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AW19_RS19345	COG3210	domain, Protein
AW19_RS19355	COG3210	domain, Protein
AW19_RS19360	COG2831	hemolysin activation secretion protein
AW19_RS19400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AW19_RS19405	COG1830	Aldolase
AW19_RS19410	COG1879	ABC-type sugar transport system periplasmic component
AW19_RS19415	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW19_RS19420	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW19_RS19425	COG1129	ABC transporter
AW19_RS19430	COG2390	Transcriptional regulator
AW19_RS19435	COG1070	Carbohydrate kinase
AW19_RS19440	COG0859	PFAM glycosyl transferase family 9
AW19_RS19455	COG2235	arginine
AW19_RS19460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS19465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW19_RS19475	COG2376	Dihydroxyacetone kinase
AW19_RS19480	COG1461	Dihydroxyacetone kinase
AW19_RS19485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW19_RS19485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AW19_RS19485	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AW19_RS19495	COG2192	nodulation
AW19_RS19520	COG3284	Transcriptional regulator
AW19_RS19545	COG0583	DNA-binding transcription factor activity
AW19_RS19550	COG0667	Aldo Keto reductase
AW19_RS19555	COG2813	Specifically methylates the guanine in position
AW19_RS19560	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AW19_RS19565	COG0456	acetyltransferase
AW19_RS19570	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AW19_RS19575	COG2823	Periplasmic or secreted lipoprotein
AW19_RS19580	COG4667	esterase of the alpha-beta hydrolase superfamily
AW19_RS19585	COG0084	hydrolase, TatD family'
AW19_RS19590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW19_RS19600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW19_RS19605	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AW19_RS19615	COG3726	membrane protein affecting hemolysin expression
AW19_RS19620	COG0560	Phosphoserine phosphatase
AW19_RS19640	COG0604	alcohol dehydrogenase
AW19_RS19650	COG0488	(ABC) transporter
AW19_RS19655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW19_RS19660	COG0741	lytic transglycosylase activity
AW19_RS19665	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AW19_RS19670	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AW19_RS19680	COG3708	Transcriptional regulator
AW19_RS19680	COG2207	Transcriptional regulator
AW19_RS19685	COG3045	CreA protein
AW19_RS19690	COG0745	RESPONSE REGULATOR receiver
AW19_RS19705	COG0083	homoserine kinase activity
AW19_RS19715	COG3022	response to hydroperoxide
AW19_RS19720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW19_RS19725	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW19_RS19730	COG0477	Major facilitator Superfamily
AW19_RS19740	COG1584	GPR1 FUN34 yaaH family protein
AW19_RS19750	COG0484	heat shock protein binding
AW19_RS19755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AW19_RS19760	COG0583	DNA-binding transcription factor activity
AW19_RS19770	COG0196	riboflavin kinase activity
AW19_RS19775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW19_RS19780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AW19_RS19785	COG1047	Peptidyl-prolyl cis-trans
AW19_RS19790	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AW19_RS19795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AW19_RS19805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AW19_RS19810	COG1280	lysine exporter protein (LysE YggA)
AW19_RS19815	COG2966	Psort location CytoplasmicMembrane, score
AW19_RS19825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW19_RS19840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW19_RS19845	COG2967	ApaG domain
AW19_RS19855	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AW19_RS19865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AW19_RS19875	COG0564	pseudouridine synthase activity
AW19_RS19880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW19_RS19885	COG0417	DNA replication proofreading
AW19_RS19890	COG0586	Pfam SNARE associated Golgi protein
AW19_RS19900	COG1178	ABC-type Fe3 transport system permease component
AW19_RS19905	COG4143	(ABC) transporter
AW19_RS19910	COG4533	DNA binding
AW19_RS19915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW19_RS19920	COG1882	Formate acetyltransferase
AW19_RS19925	COG2814	Major facilitator Superfamily
AW19_RS19930	COG3033	Beta-eliminating lyase
AW19_RS19940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AW19_RS19945	COG0473	3-isopropylmalate dehydrogenase activity
AW19_RS19950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW19_RS19960	COG1022	Amp-dependent synthetase and ligase
AW19_RS19965	COG0028	Belongs to the TPP enzyme family
AW19_RS19985	COG2001	Belongs to the MraZ family
AW19_RS19990	COG0275	rRNA processing
AW19_RS19995	COG3116	cell division
AW19_RS20000	COG0768	penicillin binding
AW19_RS20005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW19_RS20010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW19_RS20025	COG0772	Belongs to the SEDS family
AW19_RS20030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW19_RS20035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AW19_RS20045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW19_RS20050	COG0849	cell division
AW19_RS20055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW19_RS20075	COG0653	protein targeting
AW19_RS20080	COG0494	nUDIX hydrolase
AW19_RS20085	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AW19_RS20100	COG0516	GMP reductase activity
AW19_RS20105	COG1459	type II secretion system
AW19_RS20110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW19_RS20115	COG4969	Belongs to the N-Me-Phe pilin family
AW19_RS20130	COG3725	Membrane protein required for beta-lactamase induction
AW19_RS20135	COG1113	amino acid transport
AW19_RS20140	COG2186	Transcriptional regulator
AW19_RS20145	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AW19_RS20150	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW19_RS20155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW19_RS20165	COG4977	sequence-specific DNA binding
AW19_RS20175	COG1049	propionate catabolic process, 2-methylcitrate cycle
AW19_RS20180	COG3112	Uncharacterised protein family (UPF0231)
AW19_RS20185	COG0697	spore germination
AW19_RS20200	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW19_RS20205	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW19_RS20215	COG2132	Multicopper oxidase
AW19_RS20225	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AW19_RS20230	COG0288	reversible hydration of carbon dioxide
AW19_RS20235	COG1131	(ABC) transporter
AW19_RS20240	COG0842	Transport permease protein
AW19_RS20245	COG0726	polysaccharide deacetylase
AW19_RS20250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AW19_RS20255	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AW19_RS20260	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AW19_RS20265	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW19_RS20270	COG0617	tRNA 3'-terminal CCA addition
AW19_RS20285	COG1489	DNA binding
AW19_RS20290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AW19_RS20295	COG1643	Atp-dependent helicase
AW19_RS20300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW19_RS20305	COG1120	ATPase activity
AW19_RS20310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW19_RS20315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW19_RS20320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AW19_RS20330	COG0316	Belongs to the HesB IscA family
AW19_RS20335	COG2860	membrane
AW19_RS20345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW19_RS20350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AW19_RS20355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW19_RS20360	COG2205	protein histidine kinase activity
AW19_RS20360	COG3437	response regulator, receiver
AW19_RS20360	COG3850	Histidine kinase
AW19_RS20360	COG4999	Histidine kinase
AW19_RS20370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW19_RS20375	COG3956	TIGRFAM MazG family protein
AW19_RS20380	COG0504	CTP synthase activity
AW19_RS20385	COG0148	phosphopyruvate hydratase activity
AW19_RS20410	COG0602	queuosine metabolic process
AW19_RS20415	COG0720	synthase
AW19_RS20420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AW19_RS20425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW19_RS20430	COG0175	sulfate reduction
AW19_RS20435	COG2234	aminopeptidase activity
AW19_RS20440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW19_RS20440	COG1648	precorrin-2 dehydrogenase activity
AW19_RS20445	COG0175	sulfate reduction
AW19_RS20450	COG2895	sulfate adenylyltransferase (ATP) activity
AW19_RS20455	COG0529	Catalyzes the synthesis of activated sulfate
AW19_RS20470	COG0765	amino acid transport
AW19_RS20480	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AW19_RS20490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AW19_RS20495	COG0585	pseudouridine synthase activity
AW19_RS20500	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AW19_RS20505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AW19_RS20510	COG1388	LysM domain
AW19_RS20510	COG4942	peptidase
AW19_RS20515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW19_RS20520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AW19_RS20545	COG3188	usher protein
AW19_RS20550	COG3121	Chaperone
AW19_RS20560	COG3539	Fimbrial protein
AW19_RS20565	COG3539	Fimbrial protein
AW19_RS20595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AW19_RS20600	COG0577	efflux transmembrane transporter activity
AW19_RS20600	COG1136	(ABC) transporter
AW19_RS20605	COG1538	Outer membrane efflux protein
AW19_RS20645	COG3468	outer membrane autotransporter barrel domain protein
AW19_RS20710	COG3179	chitinase