locus-tag	class	description
FOC37_RS00005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC37_RS00010	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOC37_RS00015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOC37_RS00020	COG2105	PFAM AIG2 family protein
FOC37_RS00025	COG2911	Protein conserved in bacteria
FOC37_RS00030	COG0729	surface antigen
FOC37_RS00035	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC37_RS00040	COG1253	flavin adenine dinucleotide binding
FOC37_RS00050	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FOC37_RS00055	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOC37_RS00060	COG0737	Belongs to the 5'-nucleotidase family
FOC37_RS00070	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC37_RS00075	COG3061	Opacity-associated protein A
FOC37_RS00085	COG0359	binds to the 23S rRNA
FOC37_RS00090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC37_RS00095	COG2965	DNA replication, synthesis of RNA primer
FOC37_RS00100	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC37_RS00115	COG1073	alpha beta
FOC37_RS00120	COG3650	response to hydrogen peroxide
FOC37_RS00125	COG1960	acyl-CoA dehydrogenase activity
FOC37_RS00130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC37_RS00135	COG0557	exoribonuclease II activity
FOC37_RS00140	COG1959	2 iron, 2 sulfur cluster binding
FOC37_RS00145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC37_RS00150	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FOC37_RS00155	COG0330	HflC and HflK could
FOC37_RS00160	COG0330	HflC and HflK could
FOC37_RS00165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC37_RS00175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC37_RS00180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC37_RS00185	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC37_RS00190	COG0802	atpase or kinase
FOC37_RS00195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC37_RS00195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC37_RS00200	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC37_RS00220	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOC37_RS00225	COG1162	GTPase activity
FOC37_RS00230	COG0688	phosphatidylethanolamine metabolic process
FOC37_RS00235	COG1511	domain protein
FOC37_RS00235	COG3264	Mechanosensitive ion channel
FOC37_RS00240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOC37_RS00245	COG1053	succinate dehydrogenase
FOC37_RS00250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC37_RS00255	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOC37_RS00260	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FOC37_RS00295	COG0459	protein refolding
FOC37_RS00300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC37_RS00315	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC37_RS00325	COG4232	protein-disulfide reductase activity
FOC37_RS00330	COG3383	formate dehydrogenase (NAD+) activity
FOC37_RS00335	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS00335	COG0493	'glutamate synthase
FOC37_RS00340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS00340	COG0493	'glutamate synthase
FOC37_RS00345	COG2271	Major facilitator Superfamily
FOC37_RS00350	COG2721	sulfolactate sulfo-lyase activity
FOC37_RS00355	COG3835	regulator
FOC37_RS00360	COG1929	Belongs to the glycerate kinase type-1 family
FOC37_RS00365	COG2084	Dehydrogenase
FOC37_RS00375	COG1309	transcriptional regulator
FOC37_RS00385	COG3876	Protein conserved in bacteria
FOC37_RS00395	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC37_RS00405	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOC37_RS00410	COG1263	PTS System
FOC37_RS00410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS00425	COG0840	transmembrane signaling receptor activity
FOC37_RS00430	COG1882	Formate acetyltransferase
FOC37_RS00435	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC37_RS00440	COG0814	amino acid
FOC37_RS00450	COG0488	(ABC) transporter
FOC37_RS00465	COG3720	iron ion transport
FOC37_RS00470	COG4558	Periplasmic binding protein
FOC37_RS00475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_RS00480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOC37_RS00490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_RS00500	COG4774	siderophore transport
FOC37_RS00505	COG1511	domain protein
FOC37_RS00505	COG3264	Mechanosensitive ion channel
FOC37_RS00660	COG2205	protein histidine kinase activity
FOC37_RS00660	COG5002	protein histidine kinase activity
FOC37_RS00660	COG0784	Response regulator, receiver
FOC37_RS00670	COG1301	dicarboxylic acid transport
FOC37_RS00675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC37_RS00680	COG3162	membrane
FOC37_RS00685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC37_RS00725	COG0138	bifunctional purine biosynthesis protein purh
FOC37_RS00730	COG0151	Belongs to the GarS family
FOC37_RS00750	COG1515	deoxyribonuclease V activity
FOC37_RS00755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC37_RS00760	COG2816	NAD+ diphosphatase activity
FOC37_RS00765	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FOC37_RS00780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC37_RS00785	COG2104	thiamine diphosphate biosynthetic process
FOC37_RS00790	COG2022	thiamine diphosphate biosynthetic process
FOC37_RS00800	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC37_RS00805	COG0085	RNA polymerase activity
FOC37_RS00810	COG0222	ribosome binding
FOC37_RS00815	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC37_RS00820	COG0081	regulation of translation
FOC37_RS00825	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC37_RS00830	COG0250	Participates in transcription elongation, termination and antitermination
FOC37_RS00875	COG1072	(Pantothenic acid kinase))
FOC37_RS00880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOC37_RS00880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOC37_RS00920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC37_RS00925	COG1739	Uncharacterized protein family UPF0029
FOC37_RS00935	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC37_RS00935	COG1024	Enoyl-CoA hydratase
FOC37_RS00940	COG0183	Belongs to the thiolase family
FOC37_RS00950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOC37_RS00970	COG0805	protein transport
FOC37_RS00975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC37_RS00980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC37_RS00985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC37_RS00990	COG3165	ubiquinone biosynthetic process from chorismate
FOC37_RS00995	COG2226	methyltransferase
FOC37_RS01000	COG1322	Protein conserved in bacteria
FOC37_RS01005	COG0586	Pfam SNARE associated Golgi protein
FOC37_RS01010	COG1966	Carbon starvation protein
FOC37_RS01025	COG0412	Dienelactone hydrolase
FOC37_RS01030	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOC37_RS01035	COG0583	DNA-binding transcription factor activity
FOC37_RS01040	COG0697	spore germination
FOC37_RS01045	COG0679	Auxin Efflux Carrier
FOC37_RS01050	COG0584	glycerophosphoryl diester phosphodiesterase
FOC37_RS01055	COG3842	ATPase activity
FOC37_RS01060	COG0395	ABC-type sugar transport system, permease component
FOC37_RS01065	COG1175	transmembrane transport
FOC37_RS01070	COG1653	transport
FOC37_RS01105	COG0410	ABC transporter
FOC37_RS01115	COG4177	L-phenylalanine transmembrane transporter activity
FOC37_RS01125	COG0683	leucine binding
FOC37_RS01130	COG0456	acetyltransferase
FOC37_RS01140	COG2177	Part of the ABC transporter FtsEX involved in
FOC37_RS01145	COG2884	Cell division ATP-binding protein ftsE
FOC37_RS01150	COG0552	protein localization to endoplasmic reticulum
FOC37_RS01155	COG0742	ribosomal rna small subunit methyltransferase
FOC37_RS01160	COG3776	membrane
FOC37_RS01175	COG3714	YhhN family
FOC37_RS01180	COG2217	Heavy metal translocating P-type atpase
FOC37_RS01185	COG0425	Belongs to the sulfur carrier protein TusA family
FOC37_RS01190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOC37_RS01200	COG0247	lactate metabolic process
FOC37_RS01205	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC37_RS01210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC37_RS01220	COG2271	Major facilitator Superfamily
FOC37_RS01225	COG0584	glycerophosphoryl diester phosphodiesterase
FOC37_RS01230	COG0561	phosphatase activity
FOC37_RS01235	COG2267	carboxylic ester hydrolase activity
FOC37_RS01240	COG1280	lysine exporter protein (LysE YggA)
FOC37_RS01245	COG1280	lysine exporter protein (LysE YggA)
FOC37_RS01250	COG0514	ATP-dependent DNA helicase (RecQ)
FOC37_RS01255	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FOC37_RS01260	COG2050	protein possibly involved in aromatic compounds catabolism
FOC37_RS01280	COG5564	TIM-barrel signal transduction protein
FOC37_RS01285	COG5441	Belongs to the UPF0261 family
FOC37_RS01295	COG0210	DNA helicase
FOC37_RS01300	COG1011	Hydrolase
FOC37_RS01305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC37_RS01310	COG3159	Protein conserved in bacteria
FOC37_RS01315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOC37_RS01320	COG5567	small periplasmic lipoprotein
FOC37_RS01330	COG3072	Adenylate cyclase
FOC37_RS01335	COG0181	hydroxymethylbilane synthase activity
FOC37_RS01340	COG1587	Uroporphyrinogen-III synthase
FOC37_RS01345	COG2959	enzyme of heme biosynthesis
FOC37_RS01350	COG3071	HemY protein
FOC37_RS01390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC37_RS01395	COG2244	polysaccharide biosynthetic process
FOC37_RS01400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC37_RS01405	COG0456	acetyltransferase
FOC37_RS01410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC37_RS01415	COG1088	dTDP-glucose 4,6-dehydratase activity
FOC37_RS01420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC37_RS01425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC37_RS01430	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC37_RS01435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC37_RS01440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC37_RS01445	COG3118	belongs to the thioredoxin family
FOC37_RS01455	COG0248	Ppx GppA phosphatase
FOC37_RS01470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC37_RS01480	COG3121	Chaperone
FOC37_RS01495	COG3121	Chaperone
FOC37_RS01550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC37_RS01555	COG0583	DNA-binding transcription factor activity
FOC37_RS01565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC37_RS01575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC37_RS01580	COG3978	acetolactate synthase activity
FOC37_RS01600	COG3085	chromosome segregation
FOC37_RS01605	COG0583	DNA-binding transcription factor activity
FOC37_RS01610	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS01615	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS01620	COG1129	ABC transporter
FOC37_RS01625	COG1879	ABC-type sugar transport system periplasmic component
FOC37_RS01670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC37_RS01680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC37_RS01695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_RS01705	COG0678	peroxiredoxin activity
FOC37_RS01705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_RS01710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_RS01755	COG1629	transport
FOC37_RS01760	COG0165	Argininosuccinate lyase
FOC37_RS01780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOC37_RS01790	COG0460	homoserine dehydrogenase
FOC37_RS01790	COG0527	aspartate kinase activity
FOC37_RS01795	COG0626	cystathionine gamma-synthase activity
FOC37_RS01800	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FOC37_RS01805	COG0254	rRNA binding
FOC37_RS01810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC37_RS01815	COG1609	Transcriptional regulator
FOC37_RS01820	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC37_RS01825	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOC37_RS01830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOC37_RS01835	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC37_RS01845	COG3074	FtsZ-dependent cytokinesis
FOC37_RS01850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC37_RS01855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC37_RS01860	COG1494	fructose-1,6-bisphosphatase
FOC37_RS01865	COG2814	Major facilitator Superfamily
FOC37_RS01885	COG3152	Membrane
FOC37_RS01900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOC37_RS01910	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC37_RS01925	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FOC37_RS01940	COG3678	ATP-independent chaperone mediated protein folding
FOC37_RS01945	COG0745	RESPONSE REGULATOR receiver
FOC37_RS01950	COG2205	protein histidine kinase activity
FOC37_RS01955	COG2169	Transcriptional regulator
FOC37_RS01955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC37_RS01960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC37_RS01965	COG1045	serine acetyltransferase
FOC37_RS01970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC37_RS01975	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOC37_RS01980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_RS01985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC37_RS01990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC37_RS01995	COG4942	peptidase
FOC37_RS02000	COG2861	carbohydrate metabolic process
FOC37_RS02010	COG0156	8-amino-7-oxononanoate synthase activity
FOC37_RS02015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_RS02025	COG0859	PFAM glycosyl transferase family 9
FOC37_RS02030	COG1519	Transferase
FOC37_RS02040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC37_RS02050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC37_RS02055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC37_RS02060	COG2003	Belongs to the UPF0758 family
FOC37_RS02065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC37_RS02070	COG0756	dUTP diphosphatase activity
FOC37_RS02075	COG1309	transcriptional regulator
FOC37_RS02080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC37_RS02085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOC37_RS02090	COG1561	YicC-like family, N-terminal region
FOC37_RS02095	COG3645	SOS response
FOC37_RS02115	COG5001	Diguanylate cyclase
FOC37_RS02120	COG1024	Enoyl-CoA hydratase
FOC37_RS02125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_RS02135	COG2860	membrane
FOC37_RS02140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC37_RS02150	COG1758	RNA polymerase activity
FOC37_RS02155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC37_RS02160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC37_RS02165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC37_RS02170	COG0786	glutamate:sodium symporter activity
FOC37_RS02175	COG2233	PERMEase
FOC37_RS02180	COG2982	Protein involved in outer membrane biogenesis
FOC37_RS02200	COG3423	Transcriptional regulator
FOC37_RS02215	COG2204	response regulator
FOC37_RS02220	COG0456	acetyltransferase
FOC37_RS02225	COG1490	D-aminoacyl-tRNA deacylase activity
FOC37_RS02230	COG1295	ribonuclease BN
FOC37_RS02235	COG1011	Hydrolase
FOC37_RS02245	COG0174	glutamine synthetase
FOC37_RS02250	COG3852	Histidine kinase
FOC37_RS02260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC37_RS02270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC37_RS02275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC37_RS02275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC37_RS02280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC37_RS02285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC37_RS02290	COG3084	Protein conserved in bacteria
FOC37_RS02300	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC37_RS02330	COG2186	Transcriptional regulator
FOC37_RS02335	COG0477	Major facilitator Superfamily
FOC37_RS02340	COG1609	Transcriptional regulator
FOC37_RS02345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_RS02350	COG1879	ABC-type sugar transport system periplasmic component
FOC37_RS02355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS02365	COG1869	D-ribose catabolic process
FOC37_RS02370	COG3158	transport of potassium into the cell
FOC37_RS02375	COG0714	Associated with various cellular activities
FOC37_RS02380	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOC37_RS02390	COG2502	aspartate--ammonia ligase
FOC37_RS02395	COG1522	sequence-specific DNA binding
FOC37_RS02400	COG0716	FMN binding
FOC37_RS02405	COG0445	tRNA wobble uridine modification
FOC37_RS02410	COG0357	Ribosomal RNA small subunit methyltransferase G
FOC37_RS02415	COG3312	ion transport
FOC37_RS02420	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC37_RS02430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC37_RS02435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC37_RS02440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOC37_RS02450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOC37_RS02455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC37_RS02460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC37_RS02510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC37_RS02515	COG0573	inorganic phosphate transmembrane transporter activity
FOC37_RS02520	COG0581	inorganic phosphate transmembrane transporter activity
FOC37_RS02530	COG0704	Plays a role in the regulation of phosphate uptake
FOC37_RS02540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS02545	COG0765	amino acid transport
FOC37_RS02550	COG0765	amino acid transport
FOC37_RS02555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_RS02560	COG2252	PERMEase
FOC37_RS02575	COG4191	Histidine kinase
FOC37_RS02580	COG0431	NADPH-dependent FMN reductase
FOC37_RS02585	COG0840	transmembrane signaling receptor activity
FOC37_RS02590	COG2011	ABC-type metal ion transport system permease component
FOC37_RS02595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC37_RS02605	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC37_RS02610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC37_RS02615	COG0706	membrane insertase activity
FOC37_RS02625	COG0594	ribonuclease P activity
FOC37_RS02630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC37_RS02640	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC37_RS02645	COG0592	DNA-directed DNA polymerase activity
FOC37_RS02655	COG0187	DNA topoisomerase II activity
FOC37_RS02660	COG0561	phosphatase activity
FOC37_RS02665	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC37_RS02675	COG1940	carbohydrate kinase activity
FOC37_RS02680	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_RS02690	COG2723	6-phospho-beta-galactosidase activity
FOC37_RS02695	COG2188	Transcriptional regulator
FOC37_RS02700	COG2423	ornithine cyclodeaminase activity
FOC37_RS02715	COG2186	Transcriptional regulator
FOC37_RS02720	COG3734	2-keto-3-deoxy-galactonokinase
FOC37_RS02725	COG0800	Aldolase
FOC37_RS02730	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_RS02735	COG2271	Major facilitator Superfamily
FOC37_RS02740	COG0823	Involved in the tonB-independent uptake of proteins
FOC37_RS02745	COG5645	(Lipo)protein
FOC37_RS02765	COG3977	Valine--pyruvate aminotransferase
FOC37_RS02770	COG0366	Alpha amylase catalytic
FOC37_RS02790	COG2885	chlorophyll binding
FOC37_RS02805	COG0456	acetyltransferase
FOC37_RS02810	COG2818	Glycosylase
FOC37_RS02820	COG0751	glycine-tRNA ligase activity
FOC37_RS02830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS02830	COG2213	PTS system mannitol-specific
FOC37_RS02835	COG0246	Mannitol dehydrogenase
FOC37_RS02840	COG3722	fumarate hydratase activity
FOC37_RS02850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_RS02865	COG3077	Addiction module antitoxin, RelB DinJ family
FOC37_RS02870	COG2258	MOSC domain
FOC37_RS02875	COG0840	transmembrane signaling receptor activity
FOC37_RS02880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC37_RS02885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC37_RS02895	COG0437	4 iron, 4 sulfur cluster binding
FOC37_RS02900	COG2864	formate dehydrogenase
FOC37_RS02905	COG3058	Necessary for formate dehydrogenase activity
FOC37_RS02910	COG1921	L-seryl-tRNASec selenium transferase activity
FOC37_RS02915	COG3276	selenocysteine insertion sequence binding
FOC37_RS02925	COG3274	enterobacterial common antigen metabolic process
FOC37_RS02935	COG1335	isochorismatase
FOC37_RS02945	COG3188	usher protein
FOC37_RS02950	COG3121	Chaperone
FOC37_RS02960	COG1070	Carbohydrate kinase
FOC37_RS02965	COG2115	Belongs to the xylose isomerase family
FOC37_RS02970	COG4213	ABC transporter substrate-binding protein
FOC37_RS02980	COG4214	carbohydrate transport
FOC37_RS02985	COG2207	Transcriptional regulator
FOC37_RS02985	COG1609	Transcriptional regulator
FOC37_RS03000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC37_RS03025	COG3623	hexulose-6-phosphate isomerase
FOC37_RS03050	COG3121	Chaperone
FOC37_RS03055	COG3539	Fimbrial protein
FOC37_RS03065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOC37_RS03070	COG2986	histidine ammonia-lyase
FOC37_RS03090	COG1764	response to oxidative stress
FOC37_RS03095	COG2194	sulfuric ester hydrolase activity
FOC37_RS03100	COG2197	response regulator
FOC37_RS03105	COG3851	Histidine kinase
FOC37_RS03110	COG2271	Major facilitator Superfamily
FOC37_RS03120	COG0747	negative chemotaxis
FOC37_RS03125	COG0601	transmembrane transport
FOC37_RS03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_RS03135	COG0444	Belongs to the ABC transporter superfamily
FOC37_RS03140	COG4608	Belongs to the ABC transporter superfamily
FOC37_RS03145	COG2194	sulfuric ester hydrolase activity
FOC37_RS03165	COG1192	Involved in chromosome partitioning
FOC37_RS03175	COG1215	transferase activity, transferring glycosyl groups
FOC37_RS03180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC37_RS03185	COG0457	Tetratricopeptide repeat
FOC37_RS03185	COG3118	belongs to the thioredoxin family
FOC37_RS03190	COG2199	diguanylate cyclase activity
FOC37_RS03190	COG2200	EAL domain
FOC37_RS03200	COG3121	Chaperone
FOC37_RS03205	COG3188	usher protein
FOC37_RS03215	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_RS03230	COG1301	dicarboxylic acid transport
FOC37_RS03235	COG0612	Peptidase, M16
FOC37_RS03240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_RS03245	COG1942	4-Oxalocrotonate Tautomerase
FOC37_RS03250	COG2200	EAL domain
FOC37_RS03255	COG2982	Protein involved in outer membrane biogenesis
FOC37_RS03260	COG2134	cdp-diacylglycerol pyrophosphatase
FOC37_RS03265	COG1295	ribonuclease BN
FOC37_RS03270	COG1396	sequence-specific DNA binding
FOC37_RS03280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_RS03285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOC37_RS03295	COG0742	ribosomal rna small subunit methyltransferase
FOC37_RS03300	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FOC37_RS03310	COG0589	response to stress
FOC37_RS03320	COG0306	phosphate transporter
FOC37_RS03325	COG2081	HI0933 family
FOC37_RS03340	COG0583	DNA-binding transcription factor activity
FOC37_RS03345	COG2814	Major facilitator Superfamily
FOC37_RS03360	COG3718	enzyme involved in inositol metabolism
FOC37_RS03375	COG3962	Belongs to the TPP enzyme family
FOC37_RS03380	COG0673	inositol 2-dehydrogenase activity
FOC37_RS03385	COG1082	Xylose isomerase domain protein TIM barrel
FOC37_RS03390	COG1247	-acetyltransferase
FOC37_RS03395	COG1741	Belongs to the pirin family
FOC37_RS03400	COG1609	Transcriptional regulator
FOC37_RS03405	COG2610	gluconate transmembrane transporter activity
FOC37_RS03410	COG3265	gluconokinase activity
FOC37_RS03415	COG2095	MarC family integral membrane protein
FOC37_RS03420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC37_RS03440	COG3275	phosphorelay sensor kinase activity
FOC37_RS03445	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC37_RS03450	COG1523	belongs to the glycosyl hydrolase 13 family
FOC37_RS03455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC37_RS03460	COG0297	glycogen (starch) synthase activity
FOC37_RS03465	COG0058	SHG alpha-glucan phosphorylase activity
FOC37_RS03470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC37_RS03475	COG1349	DNA-binding transcription factor activity
FOC37_RS03480	COG0705	Rhomboid family
FOC37_RS03490	COG2909	trisaccharide binding
FOC37_RS03495	COG0058	SHG alpha-glucan phosphorylase activity
FOC37_RS03500	COG1640	4-alpha-glucanotransferase
FOC37_RS03505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC37_RS03505	COG0316	Belongs to the HesB IscA family
FOC37_RS03515	COG0596	Alpha beta hydrolase
FOC37_RS03535	COG1918	ferrous iron import across plasma membrane
FOC37_RS03540	COG2183	response to ionizing radiation
FOC37_RS03545	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC37_RS03570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC37_RS03575	COG1011	Hydrolase
FOC37_RS03585	COG0494	nUDIX hydrolase
FOC37_RS03590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC37_RS03615	COG4796	Type ii and iii secretion system protein
FOC37_RS03620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC37_RS03640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC37_RS03650	COG0180	Tryptophanyl-tRNA synthetase
FOC37_RS03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC37_RS03655	COG1648	precorrin-2 dehydrogenase activity
FOC37_RS03670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC37_RS03675	COG0402	S-adenosylhomocysteine deaminase activity
FOC37_RS03680	COG0738	Major facilitator superfamily
FOC37_RS03700	COG1486	melibiose metabolic process
FOC37_RS03705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC37_RS03710	COG0433	COG0433 Predicted ATPase
FOC37_RS03725	COG1289	transmembrane transporter activity
FOC37_RS03735	COG1765	OsmC-like protein
FOC37_RS03740	COG3954	Phosphoribulokinase
FOC37_RS03745	COG3089	Belongs to the UPF0270 family
FOC37_RS03750	COG0429	hydrolase of the alpha beta-hydrolase fold
FOC37_RS03765	COG4521	taurine ABC transporter
FOC37_RS03775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC37_RS03780	COG2175	clavaminate synthase activity
FOC37_RS03790	COG1216	Glycosyl transferase, family 2
FOC37_RS03795	COG0488	(ABC) transporter
FOC37_RS03800	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_RS03810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOC37_RS03815	COG1047	Peptidyl-prolyl cis-trans
FOC37_RS03825	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC37_RS03830	COG2964	Protein conserved in bacteria
FOC37_RS03835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOC37_RS03840	COG2923	Belongs to the DsrF TusC family
FOC37_RS03845	COG2168	tRNA wobble position uridine thiolation
FOC37_RS03850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC37_RS03855	COG0049	tRNA binding
FOC37_RS03865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC37_RS03880	COG0051	transcription antitermination factor activity, RNA binding
FOC37_RS03895	COG0089	rRNA binding
FOC37_RS03905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC37_RS03915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOC37_RS03920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC37_RS03925	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC37_RS03930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC37_RS03935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOC37_RS03940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC37_RS03950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC37_RS03955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOC37_RS03960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC37_RS03965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC37_RS03970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC37_RS03975	COG1841	ribosomal large subunit assembly
FOC37_RS03980	COG0200	Binds to the 23S rRNA
FOC37_RS03985	COG0201	protein transport
FOC37_RS03990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC37_RS03995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC37_RS04000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC37_RS04005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC37_RS04015	COG0203	ribosomal protein L17
FOC37_RS04025	COG0789	Transcriptional regulator
FOC37_RS04030	COG3036	rescue of stalled ribosome
FOC37_RS04035	COG1970	mechanosensitive ion channel activity
FOC37_RS04040	COG0569	domain protein
FOC37_RS04045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC37_RS04045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC37_RS04050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC37_RS04055	COG0242	peptide deformylase activity
FOC37_RS04060	COG0758	DNA mediated transformation
FOC37_RS04070	COG0551	DNA topoisomerase type I activity
FOC37_RS04075	COG0009	L-threonylcarbamoyladenylate synthase
FOC37_RS04080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC37_RS04085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC37_RS04125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOC37_RS04130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC37_RS04135	COG2224	Isocitrate lyase
FOC37_RS04140	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FOC37_RS04145	COG0183	Belongs to the thiolase family
FOC37_RS04150	COG2031	fatty acid transporter
FOC37_RS04155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC37_RS04160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC37_RS04165	COG2204	response regulator
FOC37_RS04170	COG3852	Histidine kinase
FOC37_RS04175	COG1414	Transcriptional regulator
FOC37_RS04200	COG0527	aspartate kinase activity
FOC37_RS04210	COG3223	Belongs to the PsiE family
FOC37_RS04215	COG3833	ABC-type maltose transport systems, permease component
FOC37_RS04220	COG1175	transmembrane transport
FOC37_RS04240	COG4580	involved in the transport of maltose and maltodextrins
FOC37_RS04255	COG3161	chorismate lyase activity
FOC37_RS04265	COG2937	Belongs to the GPAT DAPAT family
FOC37_RS04270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC37_RS04275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC37_RS04280	COG3237	CsbD-like
FOC37_RS04285	COG0735	belongs to the Fur family
FOC37_RS04295	COG2131	deaminase
FOC37_RS04340	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOC37_RS04345	COG5532	Uncharacterized conserved protein (DUF2303)
FOC37_RS04380	COG3645	SOS response
FOC37_RS04380	COG3646	Phage regulatory protein
FOC37_RS04385	COG1403	HNH endonuclease
FOC37_RS04565	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC37_RS04575	COG0604	alcohol dehydrogenase
FOC37_RS04590	COG1448	Aminotransferase
FOC37_RS04595	COG2315	Protein conserved in bacteria
FOC37_RS04600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC37_RS04605	COG0629	single-stranded DNA binding
FOC37_RS04610	COG3550	peptidyl-serine autophosphorylation
FOC37_RS04625	COG2252	PERMEase
FOC37_RS04630	COG0025	NhaP-type Na H and K H
FOC37_RS04635	COG0583	DNA-binding transcription factor activity
FOC37_RS04640	COG1380	Effector of murein hydrolase LrgA
FOC37_RS04650	COG1126	abc transporter atp-binding protein
FOC37_RS04655	COG0765	amino acid transport
FOC37_RS04660	COG4597	amino acid ABC transporter
FOC37_RS04665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS04675	COG1560	Kdo2-lipid A biosynthetic process
FOC37_RS04685	COG1129	ABC transporter
FOC37_RS04690	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS04700	COG1069	ribulokinase activity
FOC37_RS04710	COG0471	metal ion transport
FOC37_RS04715	COG1278	Cold shock
FOC37_RS04720	COG1278	Cold shock
FOC37_RS04725	COG3133	Outer membrane lipoprotein
FOC37_RS04730	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOC37_RS04735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC37_RS04740	COG2264	protein methyltransferase activity
FOC37_RS04745	COG4145	pantothenate transmembrane transporter activity
FOC37_RS04750	COG3924	membrane
FOC37_RS04755	COG0439	Biotin carboxylase
FOC37_RS04760	COG0511	ligase activity, forming carbon-carbon bonds
FOC37_RS04770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOC37_RS04780	COG0604	alcohol dehydrogenase
FOC37_RS04785	COG2199	diguanylate cyclase activity
FOC37_RS04785	COG2200	EAL domain
FOC37_RS04790	COG1077	Cell shape determining protein MreB Mrl
FOC37_RS04795	COG1792	Involved in formation and maintenance of cell shape
FOC37_RS04800	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOC37_RS04805	COG0424	maF-like protein
FOC37_RS04810	COG1530	ribonuclease E activity
FOC37_RS04815	COG3164	Protein of unknown function
FOC37_RS04820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC37_RS04825	COG0312	modulator of DNA gyrase
FOC37_RS04830	COG0583	DNA-binding transcription factor activity
FOC37_RS04840	COG1566	PFAM secretion protein HlyD family protein
FOC37_RS04845	COG1289	transmembrane transporter activity
FOC37_RS04850	COG1012	belongs to the aldehyde dehydrogenase family
FOC37_RS04860	COG2732	(Barnase) inhibitor
FOC37_RS04865	COG3028	Belongs to the UPF0307 family
FOC37_RS04870	COG0312	modulator of DNA gyrase
FOC37_RS04875	COG3783	Cytochrome b(562)
FOC37_RS04880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC37_RS04910	COG3964	amidohydrolase
FOC37_RS04925	COG3711	transcriptional antiterminator
FOC37_RS04925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS04930	COG3093	addiction module antidote protein HigA
FOC37_RS04940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC37_RS04950	COG1263	PTS System
FOC37_RS04950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS04955	COG0366	Alpha amylase catalytic
FOC37_RS04970	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOC37_RS04975	COG0540	Belongs to the ATCase OTCase family
FOC37_RS04980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_RS04985	COG2271	Major facilitator Superfamily
FOC37_RS04990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS04995	COG1660	Displays ATPase and GTPase activities
FOC37_RS05010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC37_RS05015	COG1137	ATPase activity
FOC37_RS05020	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOC37_RS05025	COG3117	lipopolysaccharide transmembrane transporter activity
FOC37_RS05030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOC37_RS05035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOC37_RS05035	COG0517	IMP dehydrogenase activity
FOC37_RS05040	COG0530	calcium, potassium:sodium antiporter activity
FOC37_RS05045	COG1127	ABC transporter
FOC37_RS05050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC37_RS05055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC37_RS05060	COG2854	intermembrane phospholipid transfer
FOC37_RS05065	COG3113	response to antibiotic
FOC37_RS05070	COG5007	Belongs to the BolA IbaG family
FOC37_RS05075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC37_RS05080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC37_RS05085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC37_RS05090	COG3105	Protein conserved in bacteria
FOC37_RS05095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOC37_RS05100	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC37_RS05105	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC37_RS05110	COG0625	glutathione transferase activity
FOC37_RS05115	COG2969	positive regulation of protein catabolic process
FOC37_RS05125	COG0493	'glutamate synthase
FOC37_RS05130	COG0070	glutamate synthase
FOC37_RS05130	COG0067	glutamate synthase
FOC37_RS05130	COG0069	glutamate synthase activity
FOC37_RS05135	COG1242	4 iron, 4 sulfur cluster binding
FOC37_RS05140	COG0784	Response regulator, receiver
FOC37_RS05140	COG5002	protein histidine kinase activity
FOC37_RS05140	COG2198	Histidine kinase
FOC37_RS05145	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FOC37_RS05150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC37_RS05155	COG2823	Periplasmic or secreted lipoprotein
FOC37_RS05160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC37_RS05165	COG0792	nuclease activity
FOC37_RS05175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC37_RS05190	COG1064	alcohol dehydrogenase
FOC37_RS05195	COG1741	Belongs to the pirin family
FOC37_RS05200	COG0583	DNA-binding transcription factor activity
FOC37_RS05205	COG0435	Glutathione S-transferase
FOC37_RS05210	COG2259	Doxx family
FOC37_RS05220	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FOC37_RS05225	COG4575	ribosome binding
FOC37_RS05240	COG0586	Pfam SNARE associated Golgi protein
FOC37_RS05255	COG2271	Major facilitator Superfamily
FOC37_RS05265	COG0246	Mannitol dehydrogenase
FOC37_RS05270	COG2721	sulfolactate sulfo-lyase activity
FOC37_RS05280	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOC37_RS05285	COG0861	Integral membrane protein TerC family
FOC37_RS05290	COG0673	inositol 2-dehydrogenase activity
FOC37_RS05295	COG1451	nucleotide metabolic process
FOC37_RS05300	COG3468	outer membrane autotransporter barrel domain protein
FOC37_RS05305	COG2813	Specifically methylates the guanine in position
FOC37_RS05310	COG1902	pentaerythritol trinitrate reductase activity
FOC37_RS05310	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC37_RS05320	COG2378	regulation of single-species biofilm formation
FOC37_RS05330	COG3247	response to pH
FOC37_RS05335	COG2814	Major facilitator Superfamily
FOC37_RS05370	COG0358	DNA primase activity
FOC37_RS05375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC37_RS05380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC37_RS05385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC37_RS05390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC37_RS05400	COG0617	tRNA 3'-terminal CCA addition
FOC37_RS05405	COG4991	sh3 domain protein
FOC37_RS05410	COG3025	triphosphatase activity
FOC37_RS05415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOC37_RS05420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC37_RS05420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC37_RS05425	COG0531	amino acid
FOC37_RS05435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC37_RS05440	COG3384	dioxygenase
FOC37_RS05445	COG0754	glutathionylspermidine amidase activity
FOC37_RS05450	COG5463	Belongs to the UPF0441 family
FOC37_RS05455	COG1538	Outer membrane efflux protein
FOC37_RS05460	COG0494	nUDIX hydrolase
FOC37_RS05465	COG3151	Protein conserved in bacteria
FOC37_RS05470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC37_RS05475	COG3150	esterase
FOC37_RS05490	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOC37_RS05495	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_RS05510	COG1653	transport
FOC37_RS05515	COG0667	Aldo Keto reductase
FOC37_RS05520	COG0583	DNA-binding transcription factor activity
FOC37_RS05530	COG3716	PTS system mannose fructose sorbose family IID component
FOC37_RS05535	COG3715	PTS system
FOC37_RS05540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS05545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC37_RS05550	COG0204	Acyl-transferase
FOC37_RS05555	COG2132	Multicopper oxidase
FOC37_RS05575	COG0656	L-ascorbic acid biosynthetic process
FOC37_RS05580	COG1979	alcohol dehydrogenase
FOC37_RS05585	COG2207	Transcriptional regulator
FOC37_RS05590	COG0586	Pfam SNARE associated Golgi protein
FOC37_RS05595	COG0626	cystathionine gamma-synthase activity
FOC37_RS05605	COG0848	biopolymer transport protein
FOC37_RS05650	COG4964	Belongs to the GSP D family
FOC37_RS05680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_RS05685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS05705	COG4774	siderophore transport
FOC37_RS05715	COG1120	ATPase activity
FOC37_RS05720	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_RS05725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_RS05730	COG4592	Periplasmic binding protein
FOC37_RS05735	COG0840	transmembrane signaling receptor activity
FOC37_RS05755	COG3133	Outer membrane lipoprotein
FOC37_RS05760	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FOC37_RS05765	COG0437	4 iron, 4 sulfur cluster binding
FOC37_RS05770	COG5557	Pfam Polysulphide reductase, NrfD
FOC37_RS05775	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOC37_RS05780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC37_RS05785	COG1773	rubredoxin
FOC37_RS05795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC37_RS05795	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC37_RS05800	COG0298	carbon dioxide binding
FOC37_RS05805	COG0409	Hydrogenase expression formation protein
FOC37_RS05810	COG0309	Hydrogenase expression formation protein (HypE)
FOC37_RS05815	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC37_RS05820	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FOC37_RS05825	COG5001	Diguanylate cyclase
FOC37_RS05835	COG4303	Ethanolamine ammonia lyase large subunit
FOC37_RS05840	COG4302	ethanolamine ammonia-lyase activity
FOC37_RS05845	COG0477	Major facilitator Superfamily
FOC37_RS05870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FOC37_RS05875	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC37_RS05880	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC37_RS05885	COG4607	ABC-type enterochelin transport system periplasmic component
FOC37_RS05895	COG4605	iron ion homeostasis
FOC37_RS05900	COG4604	ABC transporter, ATP-binding protein
FOC37_RS05960	COG1289	transmembrane transporter activity
FOC37_RS05995	COG3121	Chaperone
FOC37_RS06000	COG3121	Chaperone
FOC37_RS06005	COG3188	usher protein
FOC37_RS06035	COG2040	homocysteine
FOC37_RS06040	COG0833	amino acid
FOC37_RS06080	COG3038	cytochrome b561
FOC37_RS06085	COG0789	Transcriptional regulator
FOC37_RS06095	COG0300	oxidoreductase activity
FOC37_RS06110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC37_RS06125	COG3447	MASE1 domain protein
FOC37_RS06125	COG5002	protein histidine kinase activity
FOC37_RS06125	COG5001	Diguanylate cyclase
FOC37_RS06130	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC37_RS06145	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOC37_RS06150	COG2190	(PTS) system
FOC37_RS06150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS06150	COG1263	PTS System
FOC37_RS06170	COG2188	Transcriptional regulator
FOC37_RS06175	COG2771	luxR family
FOC37_RS06180	COG3916	Acyl-homoserine-lactone synthase
FOC37_RS06185	COG4810	utilization protein
FOC37_RS06195	COG4766	ethanolamine catabolic process
FOC37_RS06210	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC37_RS06215	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOC37_RS06245	COG4303	Ethanolamine ammonia lyase large subunit
FOC37_RS06270	COG2207	Transcriptional regulator
FOC37_RS06320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC37_RS06465	COG0789	Transcriptional regulator
FOC37_RS06480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC37_RS06550	COG2132	Multicopper oxidase
FOC37_RS06565	COG2205	protein histidine kinase activity
FOC37_RS06570	COG0745	RESPONSE REGULATOR receiver
FOC37_RS06575	COG1276	copper resistance
FOC37_RS06580	COG2372	response to copper ion
FOC37_RS06585	COG3667	copper resistance
FOC37_RS06590	COG2132	Multicopper oxidase
FOC37_RS06605	COG0739	heme binding
FOC37_RS06645	COG0745	RESPONSE REGULATOR receiver
FOC37_RS06660	COG4251	negative regulation of phosphorylation
FOC37_RS06660	COG3706	GGDEF domain
FOC37_RS06660	COG5001	Diguanylate cyclase
FOC37_RS06660	COG2203	Gaf domain
FOC37_RS06685	COG0431	NADPH-dependent FMN reductase
FOC37_RS06700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC37_RS06710	COG1982	Orn Lys Arg decarboxylase major
FOC37_RS06720	COG0741	lytic transglycosylase activity
FOC37_RS06730	COG1194	a g-specific adenine glycosylase
FOC37_RS06735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC37_RS06740	COG3171	Protein conserved in bacteria
FOC37_RS06755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC37_RS06760	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC37_RS06765	COG1872	DUF167
FOC37_RS06770	COG0762	integral membrane protein
FOC37_RS06775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC37_RS06780	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC37_RS06785	COG2805	Type II/IV secretion system protein
FOC37_RS06795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC37_RS06800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOC37_RS06805	COG1678	Uncharacterized ACR, COG1678
FOC37_RS06810	COG0189	ligase activity
FOC37_RS06815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC37_RS06820	COG2356	endonuclease I
FOC37_RS06825	COG3091	SprT-like family
FOC37_RS06830	COG0640	Transcriptional regulator
FOC37_RS06840	COG2391	methyltransferase activity
FOC37_RS06845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC37_RS06850	COG1166	arginine decarboxylase activity
FOC37_RS06860	COG0501	Belongs to the peptidase M48B family
FOC37_RS06865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC37_RS06870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC37_RS06875	COG0126	phosphoglycerate kinase activity
FOC37_RS06880	COG0191	fructose-bisphosphate aldolase activity
FOC37_RS06890	COG1279	arginine transmembrane transporter activity
FOC37_RS06900	COG0583	DNA-binding transcription factor activity
FOC37_RS06905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC37_RS06910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC37_RS06915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC37_RS06925	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOC37_RS06930	COG3079	Belongs to the UPF0149 family
FOC37_RS06935	COG0006	proline dipeptidase activity
FOC37_RS06940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC37_RS06945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC37_RS06950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC37_RS06955	COG0509	glycine decarboxylation via glycine cleavage system
FOC37_RS06960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC37_RS06960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC37_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS06975	COG1272	protein, Hemolysin III
FOC37_RS06980	COG0354	folic acid binding
FOC37_RS06995	COG0745	RESPONSE REGULATOR receiver
FOC37_RS07000	COG2205	protein histidine kinase activity
FOC37_RS07005	COG4452	Inner membrane protein CreD
FOC37_RS07010	COG0716	FMN binding
FOC37_RS07015	COG4974	Belongs to the 'phage' integrase family
FOC37_RS07020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC37_RS07025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC37_RS07055	COG3706	GGDEF domain
FOC37_RS07060	COG1522	sequence-specific DNA binding
FOC37_RS07075	COG2271	Major facilitator Superfamily
FOC37_RS07085	COG0484	heat shock protein binding
FOC37_RS07095	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS07100	COG1733	regulation of RNA biosynthetic process
FOC37_RS07105	COG0288	reversible hydration of carbon dioxide
FOC37_RS07125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC37_RS07140	COG2165	general secretion pathway protein
FOC37_RS07200	COG0583	DNA-binding transcription factor activity
FOC37_RS07205	COG0583	DNA-binding transcription factor activity
FOC37_RS07220	COG1609	Transcriptional regulator
FOC37_RS07230	COG0318	PFAM AMP-dependent synthetase and ligase
FOC37_RS07230	COG0204	Acyl-transferase
FOC37_RS07235	COG0477	Major facilitator Superfamily
FOC37_RS07240	COG0667	Aldo Keto reductase
FOC37_RS07245	COG0861	Integral membrane protein TerC family
FOC37_RS07250	COG3066	DNA modification
FOC37_RS07265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOC37_RS07275	COG2165	general secretion pathway protein
FOC37_RS07280	COG4795	General secretion pathway protein
FOC37_RS07295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOC37_RS07300	COG1025	Belongs to the peptidase M16 family
FOC37_RS07305	COG1074	ATP-dependent DNA helicase activity
FOC37_RS07310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC37_RS07315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC37_RS07315	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOC37_RS07320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC37_RS07340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOC37_RS07345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC37_RS07350	COG2166	iron-sulfur cluster assembly
FOC37_RS07355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC37_RS07365	COG0583	DNA-binding transcription factor activity
FOC37_RS07370	COG2363	Small membrane protein
FOC37_RS07375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FOC37_RS07380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC37_RS07385	COG1611	Belongs to the LOG family
FOC37_RS07390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC37_RS07390	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC37_RS07400	COG3098	single-species biofilm formation
FOC37_RS07405	COG0564	pseudouridine synthase activity
FOC37_RS07420	COG2171	N-acyltransferase activity
FOC37_RS07425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOC37_RS07435	COG0052	Belongs to the universal ribosomal protein uS2 family
FOC37_RS07440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC37_RS07445	COG0528	UMP kinase activity
FOC37_RS07450	COG0233	cytoplasmic translational termination
FOC37_RS07455	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC37_RS07465	COG0575	Belongs to the CDS family
FOC37_RS07470	COG0750	zinc metalloprotease
FOC37_RS07480	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FOC37_RS07485	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_RS07490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC37_RS07495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_RS07505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC37_RS07515	COG0825	malonyl-CoA metabolic process
FOC37_RS07520	COG1982	Orn Lys Arg decarboxylase major
FOC37_RS07525	COG0346	lactoylglutathione lyase activity
FOC37_RS07540	COG4568	rho-dependent transcription termination
FOC37_RS07550	COG4681	YaeQ
FOC37_RS07560	COG3015	lipoprotein NlpE involved in copper resistance
FOC37_RS07565	COG0442	prolyl-tRNA aminoacylation
FOC37_RS07570	COG1720	tRNA m6t6A37 methyltransferase activity
FOC37_RS07580	COG1464	Belongs to the NlpA lipoprotein family
FOC37_RS07585	COG2011	ABC-type metal ion transport system permease component
FOC37_RS07595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC37_RS07630	COG5544	Lipoprotein
FOC37_RS07635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC37_RS07640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_RS07640	COG1042	CoA-binding domain protein
FOC37_RS07640	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC37_RS07645	COG3148	PFAM DTW domain containing protein
FOC37_RS07650	COG3118	belongs to the thioredoxin family
FOC37_RS07655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC37_RS07660	COG2814	Major facilitator Superfamily
FOC37_RS07665	COG1566	PFAM secretion protein HlyD family protein
FOC37_RS07675	COG1846	Transcriptional regulator
FOC37_RS07685	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOC37_RS07690	COG2814	Major facilitator Superfamily
FOC37_RS07700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC37_RS07715	COG0436	Aminotransferase
FOC37_RS07720	COG0582	viral genome integration into host DNA
FOC37_RS07735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC37_RS07835	COG1192	Involved in chromosome partitioning
FOC37_RS07865	COG0305	Participates in initiation and elongation during chromosome replication
FOC37_RS07930	COG3772	lysozyme
FOC37_RS08065	COG0235	Class ii aldolase
FOC37_RS08075	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC37_RS08085	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC37_RS08100	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FOC37_RS08105	COG1960	acyl-CoA dehydrogenase activity
FOC37_RS08110	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC37_RS08115	COG0121	glutamine amidotransferase
FOC37_RS08120	COG3034	peptidoglycan biosynthetic process
FOC37_RS08130	COG1805	sodium ion transport
FOC37_RS08135	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_RS08140	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_RS08145	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC37_RS08150	COG2871	sodium ion transport
FOC37_RS08155	COG1477	protein flavinylation
FOC37_RS08160	COG2991	Protein conserved in bacteria
FOC37_RS08170	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC37_RS08175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC37_RS08180	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC37_RS08190	COG1073	alpha beta
FOC37_RS08200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC37_RS08205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC37_RS08210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_RS08215	COG2313	pseudouridylate synthase activity
FOC37_RS08220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_RS08230	COG3459	Glycosyltransferase 36 associated
FOC37_RS08245	COG2226	methyltransferase
FOC37_RS08260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC37_RS08265	COG3123	guanosine phosphorylase activity
FOC37_RS08270	COG2974	May be involved in recombination
FOC37_RS08275	COG1940	carbohydrate kinase activity
FOC37_RS08280	COG0419	ATPase involved in DNA repair
FOC37_RS08285	COG0420	3'-5' exonuclease activity
FOC37_RS08290	COG0745	RESPONSE REGULATOR receiver
FOC37_RS08295	COG5002	protein histidine kinase activity
FOC37_RS08315	COG0366	Alpha amylase catalytic
FOC37_RS08330	COG0450	alkyl hydroperoxide reductase
FOC37_RS08335	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FOC37_RS08350	COG1862	Preprotein translocase
FOC37_RS08355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC37_RS08360	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC37_RS08370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC37_RS08375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC37_RS08375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC37_RS08380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOC37_RS08390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOC37_RS08395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC37_RS08400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC37_RS08405	COG0142	geranyltranstransferase activity
FOC37_RS08415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC37_RS08415	COG0301	tRNA thio-modification
FOC37_RS08420	COG0693	protein deglycase activity
FOC37_RS08425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC37_RS08430	COG1666	GTP binding
FOC37_RS08435	COG2814	Major facilitator Superfamily
FOC37_RS08440	COG0109	protoheme IX farnesyltransferase activity
FOC37_RS08445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOC37_RS08450	COG1845	cytochrome c oxidase, subunit III
FOC37_RS08455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC37_RS08460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC37_RS08470	COG2223	nitrite transmembrane transporter activity
FOC37_RS08475	COG3056	Lipoprotein
FOC37_RS08480	COG0271	Belongs to the BolA IbaG family
FOC37_RS08495	COG0740	serine-type endopeptidase activity
FOC37_RS08500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC37_RS08505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC37_RS08510	COG0776	regulation of translation
FOC37_RS08515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC37_RS08520	COG1555	photosystem II stabilization
FOC37_RS08525	COG0824	Thioesterase
FOC37_RS08530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC37_RS08535	COG4533	DNA binding
FOC37_RS08540	COG0561	phosphatase activity
FOC37_RS08550	COG1522	sequence-specific DNA binding
FOC37_RS08555	COG1132	(ABC) transporter
FOC37_RS08560	COG1132	(ABC) transporter
FOC37_RS08565	COG0347	Belongs to the P(II) protein family
FOC37_RS08570	COG0004	ammonium transporteR
FOC37_RS08575	COG1946	Acyl-CoA thioesterase
FOC37_RS08580	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FOC37_RS08585	COG3695	enzyme binding
FOC37_RS08595	COG0582	viral genome integration into host DNA
FOC37_RS08655	COG1121	(ABC) transporter
FOC37_RS08660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_RS08665	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC37_RS08670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC37_RS08675	COG0254	rRNA binding
FOC37_RS08680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_RS08685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS08690	COG1309	transcriptional regulator
FOC37_RS08695	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOC37_RS08700	COG1196	nuclear chromosome segregation
FOC37_RS08700	COG3264	Mechanosensitive ion channel
FOC37_RS08715	COG2832	Protein of unknown function (DUF454)
FOC37_RS08720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC37_RS08730	COG0346	lactoylglutathione lyase activity
FOC37_RS08735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC37_RS08740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOC37_RS08745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC37_RS08750	COG0326	Molecular chaperone. Has ATPase activity
FOC37_RS08755	COG0563	adenylate kinase activity
FOC37_RS08760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOC37_RS08785	COG1216	Glycosyl transferase, family 2
FOC37_RS08785	COG1442	glycosyl transferase family 8
FOC37_RS08790	COG0463	Glycosyl transferase, family 2
FOC37_RS08800	COG0438	transferase activity, transferring glycosyl groups
FOC37_RS08825	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC37_RS08830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_RS08835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC37_RS08835	COG4651	solute:proton antiporter activity
FOC37_RS08840	COG2223	nitrite transmembrane transporter activity
FOC37_RS08845	COG0737	Belongs to the 5'-nucleotidase family
FOC37_RS08850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC37_RS08855	COG3735	TraB family
FOC37_RS08860	COG2217	Heavy metal translocating P-type atpase
FOC37_RS08865	COG0789	Transcriptional regulator
FOC37_RS08870	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC37_RS08875	COG0330	HflC and HflK could
FOC37_RS08880	COG3118	belongs to the thioredoxin family
FOC37_RS08885	COG0300	oxidoreductase activity
FOC37_RS08890	COG2755	lipolytic protein G-D-S-L family
FOC37_RS08895	COG4181	ATPase activity
FOC37_RS08900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOC37_RS08905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC37_RS08910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC37_RS08915	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_RS08920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC37_RS08925	COG0215	cysteine-tRNA ligase activity
FOC37_RS08930	COG2501	S4 domain
FOC37_RS08935	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC37_RS08945	COG0582	viral genome integration into host DNA
FOC37_RS09015	COG2169	Transcriptional regulator
FOC37_RS09015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC37_RS09020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC37_RS09030	COG2315	Protein conserved in bacteria
FOC37_RS09225	COG2246	polysaccharide biosynthetic process
FOC37_RS09260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC37_RS09265	COG1328	CTP reductase activity
FOC37_RS09275	COG2211	Major facilitator Superfamily
FOC37_RS09285	COG3423	Transcriptional regulator
FOC37_RS09360	COG4382	Mu-like prophage protein Gp16
FOC37_RS09415	COG4383	Mu-like prophage protein gp29
FOC37_RS09440	COG4397	Mu-like prophage major head subunit gpT
FOC37_RS09465	COG4386	tail sheath protein
FOC37_RS09530	COG1486	melibiose metabolic process
FOC37_RS09535	COG2169	Transcriptional regulator
FOC37_RS09545	COG3240	lipase activity
FOC37_RS09620	COG3122	Protein conserved in bacteria
FOC37_RS09660	COG0583	DNA-binding transcription factor activity
FOC37_RS09675	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOC37_RS09680	COG0583	DNA-binding transcription factor activity
FOC37_RS09685	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS09695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_RS09725	COG1902	pentaerythritol trinitrate reductase activity
FOC37_RS09735	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS09745	COG2610	gluconate transmembrane transporter activity
FOC37_RS09760	COG1940	carbohydrate kinase activity
FOC37_RS09765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC37_RS09770	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS09775	COG1129	ABC transporter
FOC37_RS09780	COG1879	ABC-type sugar transport system periplasmic component
FOC37_RS09785	COG1737	Transcriptional regulator
FOC37_RS09790	COG0698	ribose 5-phosphate isomerase
FOC37_RS09795	COG2850	peptidyl-arginine hydroxylation
FOC37_RS09800	COG5265	(ABC) transporter
FOC37_RS09815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC37_RS09825	COG2197	response regulator
FOC37_RS09830	COG1278	Cold shock
FOC37_RS09845	COG3706	GGDEF domain
FOC37_RS09850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC37_RS09855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC37_RS09860	COG0321	lipoyl(octanoyl) transferase activity
FOC37_RS09865	COG2921	Belongs to the UPF0250 family
FOC37_RS09870	COG1686	Belongs to the peptidase S11 family
FOC37_RS09875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FOC37_RS09880	COG0772	Belongs to the SEDS family
FOC37_RS09885	COG0768	penicillin binding
FOC37_RS09895	COG0799	negative regulation of ribosome biogenesis
FOC37_RS09900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC37_RS09905	COG1466	dna polymerase III delta subunit
FOC37_RS09910	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FOC37_RS09915	COG0495	leucyl-tRNA aminoacylation
FOC37_RS09920	COG2888	peptidyl-tyrosine sulfation
FOC37_RS09930	COG1126	abc transporter atp-binding protein
FOC37_RS09935	COG0765	amino acid transport
FOC37_RS09940	COG0765	amino acid transport
FOC37_RS09955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOC37_RS09965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC37_RS09970	COG1702	phosphate starvation-inducible protein PhoH
FOC37_RS09975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC37_RS09980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC37_RS10015	COG0367	asparagine synthase
FOC37_RS10020	COG0647	UMP catabolic process
FOC37_RS10025	COG1940	carbohydrate kinase activity
FOC37_RS10025	COG1846	Transcriptional regulator
FOC37_RS10030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC37_RS10035	COG0363	glucosamine-6-phosphate deaminase activity
FOC37_RS10040	COG2190	(PTS) system
FOC37_RS10040	COG1263	PTS System
FOC37_RS10040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS10045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC37_RS10065	COG0735	belongs to the Fur family
FOC37_RS10075	COG0840	transmembrane signaling receptor activity
FOC37_RS10085	COG0596	Alpha beta hydrolase
FOC37_RS10090	COG2831	hemolysin activation secretion protein
FOC37_RS10095	COG3210	domain, Protein
FOC37_RS10210	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FOC37_RS10215	COG0033	Phosphoglucomutase
FOC37_RS10225	COG0745	RESPONSE REGULATOR receiver
FOC37_RS10230	COG2205	protein histidine kinase activity
FOC37_RS10235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOC37_RS10240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOC37_RS10260	COG3272	Protein of unknown function (DUF1722)
FOC37_RS10270	COG5212	phosphodiesterase
FOC37_RS10275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC37_RS10280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC37_RS10285	COG1984	allophanate hydrolase subunit 2
FOC37_RS10290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOC37_RS10315	COG2009	succinate dehydrogenase
FOC37_RS10320	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOC37_RS10325	COG1053	succinate dehydrogenase
FOC37_RS10335	COG0567	Dehydrogenase, E1 component
FOC37_RS10340	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC37_RS10345	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC37_RS10350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC37_RS10355	COG0737	Belongs to the 5'-nucleotidase family
FOC37_RS10360	COG1271	oxidase subunit
FOC37_RS10365	COG1294	oxidase, subunit
FOC37_RS10370	COG4890	Cyd operon protein YbgT
FOC37_RS10375	COG3790	cyd operon protein YbgE
FOC37_RS10380	COG0824	Thioesterase
FOC37_RS10385	COG0811	peptide transport
FOC37_RS10390	COG0848	biopolymer transport protein
FOC37_RS10395	COG3064	Membrane
FOC37_RS10395	COG3064	Membrane
FOC37_RS10400	COG0823	Involved in the tonB-independent uptake of proteins
FOC37_RS10405	COG2885	chlorophyll binding
FOC37_RS10410	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOC37_RS10440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC37_RS10450	COG1230	cation diffusion facilitator family transporter
FOC37_RS10455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS10455	COG2205	protein histidine kinase activity
FOC37_RS10460	COG2197	response regulator
FOC37_RS10465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC37_RS10470	COG0588	phosphoglycerate mutase activity
FOC37_RS10480	COG2017	converts alpha-aldose to the beta-anomer
FOC37_RS10485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC37_RS10495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC37_RS10505	COG1119	ATPase activity
FOC37_RS10510	COG3585	molybdate ion transport
FOC37_RS10510	COG2005	Transcriptional regulator
FOC37_RS10520	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC37_RS10525	COG4149	molybdate abc transporter
FOC37_RS10535	COG0561	phosphatase activity
FOC37_RS10540	COG2706	6-phosphogluconolactonase activity
FOC37_RS10550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC37_RS10560	COG2226	methyltransferase
FOC37_RS10575	COG0556	nucleotide-excision repair
FOC37_RS10580	COG4628	conserved protein (DUF2132)
FOC37_RS10585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC37_RS10590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC37_RS10595	COG0315	cyclic pyranopterin monophosphate synthase activity
FOC37_RS10600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOC37_RS10605	COG0314	molybdopterin synthase activity
FOC37_RS10610	COG0670	Belongs to the BI1 family
FOC37_RS10615	COG0842	Transport permease protein
FOC37_RS10620	COG0842	Transport permease protein
FOC37_RS10625	COG1131	(ABC) transporter
FOC37_RS10630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS10635	COG1309	transcriptional regulator
FOC37_RS10640	COG0513	Belongs to the DEAD box helicase family
FOC37_RS10645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC37_RS10650	COG2239	Acts as a magnesium transporter
FOC37_RS10660	COG1686	Belongs to the peptidase S11 family
FOC37_RS10665	COG0277	FAD linked oxidase domain protein
FOC37_RS10685	COG2261	transglycosylase associated protein
FOC37_RS10695	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOC37_RS10710	COG4807	Protein conserved in bacteria
FOC37_RS10740	COG2897	thiosulfate sulfurtransferase activity
FOC37_RS10745	COG0673	inositol 2-dehydrogenase activity
FOC37_RS10755	COG1732	Glycine betaine
FOC37_RS10760	COG1174	glycine betaine transport
FOC37_RS10765	COG1125	glycine betaine transport
FOC37_RS10770	COG1174	glycine betaine transport
FOC37_RS10785	COG0583	DNA-binding transcription factor activity
FOC37_RS10795	COG0697	spore germination
FOC37_RS10815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC37_RS10820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC37_RS10825	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOC37_RS10830	COG1126	abc transporter atp-binding protein
FOC37_RS10835	COG0765	amino acid transport
FOC37_RS10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS10845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC37_RS10855	COG4106	trans-aconitate 2-methyltransferase activity
FOC37_RS10870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC37_RS10890	COG0488	(ABC) transporter
FOC37_RS10895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC37_RS10900	COG0303	'Molybdopterin
FOC37_RS10910	COG0477	Major facilitator Superfamily
FOC37_RS10920	COG1136	(ABC) transporter
FOC37_RS10950	COG0583	DNA-binding transcription factor activity
FOC37_RS10955	COG0477	Major facilitator Superfamily
FOC37_RS10960	COG0302	gtp cyclohydrolase
FOC37_RS10965	COG2311	Membrane
FOC37_RS10970	COG1609	Transcriptional regulator
FOC37_RS10990	COG2116	formate transmembrane transporter activity
FOC37_RS10995	COG3604	Transcriptional regulator
FOC37_RS11000	COG3383	formate dehydrogenase (NAD+) activity
FOC37_RS11005	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS11010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC37_RS11020	COG3260	NADH ubiquinone oxidoreductase 20
FOC37_RS11025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_RS11030	COG3261	NADH dehydrogenase
FOC37_RS11030	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FOC37_RS11035	COG0651	ATP synthesis coupled electron transport
FOC37_RS11040	COG4237	Hydrogenase 4 membrane
FOC37_RS11045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC37_RS11050	COG0650	Formate hydrogenlyase subunit 4
FOC37_RS11055	COG0651	ATP synthesis coupled electron transport
FOC37_RS11060	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS11065	COG0375	protein maturation
FOC37_RS11070	COG0298	carbon dioxide binding
FOC37_RS11075	COG2949	membrane
FOC37_RS11080	COG0281	malic enzyme
FOC37_RS11090	COG1346	cytolysis
FOC37_RS11095	COG1380	Effector of murein hydrolase LrgA
FOC37_RS11100	COG2814	Major facilitator Superfamily
FOC37_RS11120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC37_RS11120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC37_RS11125	COG0489	protein tyrosine kinase activity
FOC37_RS11130	COG0572	uridine kinase
FOC37_RS11140	COG2982	Protein involved in outer membrane biogenesis
FOC37_RS11145	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC37_RS11150	COG1253	flavin adenine dinucleotide binding
FOC37_RS11155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC37_RS11160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC37_RS11165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC37_RS11170	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC37_RS11170	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC37_RS11175	COG0107	imidazoleglycerol-phosphate synthase activity
FOC37_RS11190	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC37_RS11190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC37_RS11195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC37_RS11205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC37_RS11215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_RS11220	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS11225	COG1129	ABC transporter
FOC37_RS11230	COG0371	Dehydrogenase
FOC37_RS11240	COG0531	amino acid
FOC37_RS11245	COG2925	Exonuclease
FOC37_RS11270	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS11275	COG1129	ABC transporter
FOC37_RS11290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC37_RS11300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC37_RS11320	COG4656	Part of a membrane complex involved in electron transport
FOC37_RS11335	COG2096	Adenosyltransferase
FOC37_RS11340	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOC37_RS11355	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FOC37_RS11415	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOC37_RS11425	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FOC37_RS11490	COG1492	cobalamin metabolic process
FOC37_RS11510	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOC37_RS11515	COG0583	DNA-binding transcription factor activity
FOC37_RS11525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOC37_RS11530	COG2211	Major facilitator Superfamily
FOC37_RS11535	COG0137	argininosuccinate synthase activity
FOC37_RS11540	COG0534	Mate efflux family protein
FOC37_RS11545	COG0784	Response regulator, receiver
FOC37_RS11545	COG0835	chemotaxis
FOC37_RS11565	COG0561	phosphatase activity
FOC37_RS11570	COG1349	DNA-binding transcription factor activity
FOC37_RS11580	COG0583	DNA-binding transcription factor activity
FOC37_RS11605	COG3047	cAMP biosynthetic process
FOC37_RS11605	COG2885	chlorophyll binding
FOC37_RS11635	COG0791	NLP P60 protein
FOC37_RS11635	COG1388	LysM domain
FOC37_RS11700	COG3121	Chaperone
FOC37_RS11725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS11725	COG2205	protein histidine kinase activity
FOC37_RS11740	COG3842	ATPase activity
FOC37_RS11750	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC37_RS11755	COG2271	Major facilitator Superfamily
FOC37_RS11770	COG4565	transcriptional regulatory protein
FOC37_RS11775	COG3290	protein histidine kinase activity
FOC37_RS11780	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FOC37_RS11785	COG3052	prosthetic group binding
FOC37_RS11790	COG2301	Belongs to the HpcH HpaI aldolase family
FOC37_RS11795	COG3051	citrate lyase alpha subunit
FOC37_RS11810	COG0471	metal ion transport
FOC37_RS11825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOC37_RS11835	COG2814	Major facilitator Superfamily
FOC37_RS11845	COG2211	Major facilitator Superfamily
FOC37_RS11860	COG2204	response regulator
FOC37_RS11895	COG0251	oxidation-reduction process
FOC37_RS11910	COG3228	Belongs to the MtfA family
FOC37_RS11930	COG3121	Chaperone
FOC37_RS11945	COG3121	Chaperone
FOC37_RS11950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC37_RS11980	COG3321	synthase
FOC37_RS11980	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS11980	COG0604	alcohol dehydrogenase
FOC37_RS11985	COG3250	beta-galactosidase activity
FOC37_RS11990	COG1609	Transcriptional regulator
FOC37_RS12005	COG0840	transmembrane signaling receptor activity
FOC37_RS12010	COG1285	pathogenesis
FOC37_RS12020	COG2130	NADP-dependent
FOC37_RS12025	COG0589	response to stress
FOC37_RS12050	COG0643	Histidine kinase
FOC37_RS12050	COG2198	Histidine kinase
FOC37_RS12055	COG0835	chemotaxis
FOC37_RS12060	COG0840	transmembrane signaling receptor activity
FOC37_RS12065	COG0840	transmembrane signaling receptor activity
FOC37_RS12070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC37_RS12080	COG0745	RESPONSE REGULATOR receiver
FOC37_RS12085	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOC37_RS12090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC37_RS12095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC37_RS12110	COG3418	PFAM FlgN family protein
FOC37_RS12115	COG2747	anti-sigma28 factor FlgM
FOC37_RS12125	COG1815	bacterial-type flagellum-dependent cell motility
FOC37_RS12130	COG1558	bacterial-type flagellum-dependent cell motility
FOC37_RS12135	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOC37_RS12175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC37_RS12230	COG1317	bacterial-type flagellum organization
FOC37_RS12245	COG1677	Flagellar hook-basal body complex protein FliE
FOC37_RS12250	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC37_RS12255	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOC37_RS12285	COG1191	sigma factor activity
FOC37_RS12295	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC37_RS12300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS12305	COG0765	amino acid transport
FOC37_RS12310	COG1126	abc transporter atp-binding protein
FOC37_RS12325	COG0506	proline dehydrogenase activity
FOC37_RS12325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC37_RS12325	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOC37_RS12330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC37_RS12335	COG0672	)-iron permease
FOC37_RS12340	COG2822	iron ion transport
FOC37_RS12370	COG1113	amino acid transport
FOC37_RS12380	COG2203	Gaf domain
FOC37_RS12380	COG2199	diguanylate cyclase activity
FOC37_RS12400	COG0366	Alpha amylase catalytic
FOC37_RS12405	COG0840	transmembrane signaling receptor activity
FOC37_RS12415	COG3136	membrane protein required for alginate biosynthesis
FOC37_RS12425	COG2197	response regulator
FOC37_RS12430	COG0322	excinuclease ABC activity
FOC37_RS12435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC37_RS12535	COG3121	Chaperone
FOC37_RS12540	COG3188	usher protein
FOC37_RS12555	COG2197	response regulator
FOC37_RS12575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_RS12580	COG0561	phosphatase activity
FOC37_RS12585	COG2223	nitrite transmembrane transporter activity
FOC37_RS12595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_RS12605	COG2197	response regulator
FOC37_RS12610	COG2223	nitrite transmembrane transporter activity
FOC37_RS12615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC37_RS12620	COG1140	nitrate reductase beta subunit
FOC37_RS12625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC37_RS12630	COG2181	nitrate reductase activity
FOC37_RS12640	COG3493	citrate carrier protein
FOC37_RS12645	COG4565	transcriptional regulatory protein
FOC37_RS12650	COG3290	protein histidine kinase activity
FOC37_RS12655	COG1349	DNA-binding transcription factor activity
FOC37_RS12660	COG2084	Dehydrogenase
FOC37_RS12665	COG3395	kinase activity
FOC37_RS12670	COG0235	Class ii aldolase
FOC37_RS12675	COG3622	Belongs to the hyi family
FOC37_RS12685	COG1609	Transcriptional regulator
FOC37_RS12690	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_RS12695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_RS12700	COG2723	6-phospho-beta-galactosidase activity
FOC37_RS12705	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC37_RS12715	COG0672	)-iron permease
FOC37_RS12730	COG1136	(ABC) transporter
FOC37_RS12730	COG0577	efflux transmembrane transporter activity
FOC37_RS12740	COG1136	(ABC) transporter
FOC37_RS12740	COG0577	efflux transmembrane transporter activity
FOC37_RS12765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC37_RS12770	COG0006	proline dipeptidase activity
FOC37_RS12775	COG0457	Tetratricopeptide repeat
FOC37_RS12780	COG0726	polysaccharide deacetylase
FOC37_RS12780	COG1649	PFAM Uncharacterised BCR, COG1649
FOC37_RS12785	COG1215	transferase activity, transferring glycosyl groups
FOC37_RS12790	COG3658	cytochrome
FOC37_RS12800	COG1702	phosphate starvation-inducible protein PhoH
FOC37_RS12805	COG0387	Pfam Sodium calcium exchanger
FOC37_RS12815	COG2814	Major facilitator Superfamily
FOC37_RS12820	COG0583	DNA-binding transcription factor activity
FOC37_RS12825	COG3850	Histidine kinase
FOC37_RS12835	COG1294	oxidase, subunit
FOC37_RS12840	COG1271	oxidase subunit
FOC37_RS12845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_RS12855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC37_RS12860	COG3138	arginine N-succinyltransferase
FOC37_RS12870	COG3724	N-succinylarginine dihydrolase activity
FOC37_RS12890	COG1228	amidohydrolase
FOC37_RS12900	COG0402	S-adenosylhomocysteine deaminase activity
FOC37_RS12915	COG1129	ABC transporter
FOC37_RS12920	COG4211	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS12925	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC37_RS12935	COG4942	peptidase
FOC37_RS12945	COG0012	GTP binding
FOC37_RS12955	COG0193	aminoacyl-tRNA hydrolase activity
FOC37_RS12965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC37_RS12975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOC37_RS12980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOC37_RS12985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC37_RS12990	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC37_RS13010	COG0659	secondary active sulfate transmembrane transporter activity
FOC37_RS13015	COG3706	GGDEF domain
FOC37_RS13035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC37_RS13045	COG3381	protein complex oligomerization
FOC37_RS13055	COG0477	Major facilitator Superfamily
FOC37_RS13060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_RS13100	COG3102	Protein conserved in bacteria
FOC37_RS13105	COG3142	Participates in the control of copper homeostasis
FOC37_RS13120	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FOC37_RS13125	COG1801	Protein of unknown function DUF72
FOC37_RS13130	COG1335	isochorismatase
FOC37_RS13135	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC37_RS13140	COG0494	nUDIX hydrolase
FOC37_RS13145	COG0217	transcriptional regulatory protein
FOC37_RS13155	COG0632	four-way junction helicase activity
FOC37_RS13160	COG2255	four-way junction helicase activity
FOC37_RS13165	COG3104	oligopeptide transport
FOC37_RS13170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_RS13175	COG1121	(ABC) transporter
FOC37_RS13180	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FOC37_RS13185	COG0739	heme binding
FOC37_RS13190	COG1560	Kdo2-lipid A biosynthetic process
FOC37_RS13195	COG0469	pyruvate kinase activity
FOC37_RS13205	COG1737	Transcriptional regulator
FOC37_RS13210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC37_RS13215	COG0800	Aldolase
FOC37_RS13220	COG2076	Multidrug Resistance protein
FOC37_RS13225	COG2076	Multidrug Resistance protein
FOC37_RS13230	COG0251	oxidation-reduction process
FOC37_RS13235	COG1199	ATP-dependent helicase activity
FOC37_RS13245	COG3065	identical protein binding
FOC37_RS13250	COG0318	PFAM AMP-dependent synthetase and ligase
FOC37_RS13255	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FOC37_RS13260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOC37_RS13265	COG2894	cell division
FOC37_RS13270	COG0850	regulation of cytokinetic process
FOC37_RS13280	COG3100	YcgL domain-containing protein
FOC37_RS13285	COG2951	lytic endotransglycosylase activity
FOC37_RS13290	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC37_RS13295	COG2983	Belongs to the UPF0260 family
FOC37_RS13325	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC37_RS13330	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC37_RS13335	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC37_RS13340	COG2186	Transcriptional regulator
FOC37_RS13345	COG2719	SpoVR family
FOC37_RS13350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC37_RS13355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC37_RS13360	COG2814	Major facilitator Superfamily
FOC37_RS13365	COG2199	diguanylate cyclase activity
FOC37_RS13365	COG2202	Pas domain
FOC37_RS13365	COG2200	EAL domain
FOC37_RS13375	COG2718	Belongs to the UPF0229 family
FOC37_RS13380	COG2766	serine protein kinase
FOC37_RS13385	COG3713	MltA-interacting MipA family protein
FOC37_RS13405	COG3139	Protein of unknown function (DUF1315)
FOC37_RS13410	COG1335	isochorismatase
FOC37_RS13415	COG0252	asparaginase activity
FOC37_RS13420	COG0616	signal peptide processing
FOC37_RS13425	COG0778	Nitroreductase
FOC37_RS13435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC37_RS13445	COG0494	nUDIX hydrolase
FOC37_RS13450	COG0708	Exodeoxyribonuclease III
FOC37_RS13455	COG0583	DNA-binding transcription factor activity
FOC37_RS13490	COG0788	formyltetrahydrofolate deformylase activity
FOC37_RS13495	COG3012	SEC-C Motif Domain Protein
FOC37_RS13500	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC37_RS13505	COG0745	RESPONSE REGULATOR receiver
FOC37_RS13515	COG2916	Histone family protein nucleoid-structuring protein H-NS
FOC37_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
FOC37_RS13525	COG1454	alcohol dehydrogenase
FOC37_RS13530	COG2095	MarC family integral membrane protein
FOC37_RS13535	COG4166	transmembrane transport
FOC37_RS13550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_RS13555	COG0444	Belongs to the ABC transporter superfamily
FOC37_RS13565	COG3099	Belongs to the UPF0263 family
FOC37_RS13570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC37_RS13595	COG2350	Protein conserved in bacteria
FOC37_RS13600	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOC37_RS13610	COG2917	probably involved in intracellular septation
FOC37_RS13625	COG0727	PFAM Uncharacterised protein family (UPF0153)
FOC37_RS13630	COG3047	cAMP biosynthetic process
FOC37_RS13640	COG0159	tryptophan synthase activity
FOC37_RS13645	COG0133	tryptophan synthase activity
FOC37_RS13650	COG0135	phosphoribosylanthranilate isomerase activity
FOC37_RS13650	COG0134	indole-3-glycerol-phosphate synthase activity
FOC37_RS13660	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC37_RS13675	COG0613	PHP domain protein
FOC37_RS13680	COG0009	L-threonylcarbamoyladenylate synthase
FOC37_RS13685	COG1187	pseudouridine synthase activity
FOC37_RS13695	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS13700	COG0616	signal peptide processing
FOC37_RS13715	COG0583	DNA-binding transcription factor activity
FOC37_RS13725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC37_RS13735	COG0671	phosphoesterase, PA-phosphatase related
FOC37_RS13740	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FOC37_RS13745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOC37_RS13765	COG0023	Translation Initiation Factor
FOC37_RS13775	COG0235	Class ii aldolase
FOC37_RS13785	COG1349	DNA-binding transcription factor activity
FOC37_RS13790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC37_RS13795	COG2879	small protein
FOC37_RS13800	COG1966	Carbon starvation protein
FOC37_RS13805	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FOC37_RS13810	COG0243	molybdopterin cofactor binding
FOC37_RS13815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC37_RS13825	COG4659	FMN binding
FOC37_RS13830	COG4658	electron transport chain
FOC37_RS13835	COG2207	Transcriptional regulator
FOC37_RS13835	COG3708	Transcriptional regulator
FOC37_RS13840	COG4656	Part of a membrane complex involved in electron transport
FOC37_RS13850	COG4657	Part of a membrane complex involved in electron transport
FOC37_RS13860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOC37_RS13865	COG2274	protein secretion by the type I secretion system
FOC37_RS13870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS13885	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC37_RS13900	COG1879	ABC-type sugar transport system periplasmic component
FOC37_RS13905	COG1129	ABC transporter
FOC37_RS13910	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS13920	COG0673	inositol 2-dehydrogenase activity
FOC37_RS13925	COG0385	Bile acid
FOC37_RS13930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOC37_RS13935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS13935	COG1263	PTS System
FOC37_RS13935	COG2190	(PTS) system
FOC37_RS13940	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_RS13945	COG2188	Transcriptional regulator
FOC37_RS13950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC37_RS13955	COG1263	PTS System
FOC37_RS13955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS13960	COG1609	Transcriptional regulator
FOC37_RS13975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC37_RS13990	COG1136	(ABC) transporter
FOC37_RS14005	COG1309	transcriptional regulator
FOC37_RS14015	COG5339	Protein conserved in bacteria
FOC37_RS14025	COG0114	fumarate hydratase activity
FOC37_RS14045	COG2814	Major facilitator Superfamily
FOC37_RS14050	COG0583	DNA-binding transcription factor activity
FOC37_RS14055	COG1940	carbohydrate kinase activity
FOC37_RS14060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOC37_RS14080	COG1742	UPF0060 membrane protein
FOC37_RS14090	COG4221	oxidoreductase activity
FOC37_RS14100	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FOC37_RS14105	COG1649	PFAM Uncharacterised BCR, COG1649
FOC37_RS14125	COG1393	Belongs to the ArsC family
FOC37_RS14130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC37_RS14155	COG0625	glutathione transferase activity
FOC37_RS14160	COG3604	Transcriptional regulator
FOC37_RS14165	COG0426	domain, Protein
FOC37_RS14165	COG1773	rubredoxin
FOC37_RS14170	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC37_RS14180	COG1522	sequence-specific DNA binding
FOC37_RS14190	COG4215	(ABC) transporter
FOC37_RS14205	COG1477	protein flavinylation
FOC37_RS14210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC37_RS14220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC37_RS14250	COG0028	Belongs to the TPP enzyme family
FOC37_RS14255	COG0440	acetolactate synthase activity
FOC37_RS14260	COG0251	oxidation-reduction process
FOC37_RS14265	COG1011	Hydrolase
FOC37_RS14275	COG0583	DNA-binding transcription factor activity
FOC37_RS14290	COG0738	Major facilitator superfamily
FOC37_RS14295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC37_RS14305	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS14315	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOC37_RS14330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC37_RS14335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC37_RS14340	COG0589	response to stress
FOC37_RS14345	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOC37_RS14350	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOC37_RS14365	COG0531	amino acid
FOC37_RS14375	COG0745	RESPONSE REGULATOR receiver
FOC37_RS14380	COG2205	protein histidine kinase activity
FOC37_RS14385	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC37_RS14395	COG3591	Belongs to the peptidase S1B family
FOC37_RS14410	COG1643	Atp-dependent helicase
FOC37_RS14415	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC37_RS14420	COG3784	Protein of unknown function (DUF1318)
FOC37_RS14430	COG2911	Protein conserved in bacteria
FOC37_RS14435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC37_RS14440	COG3042	response to heat
FOC37_RS14445	COG1285	pathogenesis
FOC37_RS14455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC37_RS14455	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC37_RS14455	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC37_RS14455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_RS14460	COG0037	tRNA processing
FOC37_RS14465	COG0598	Magnesium transport protein CorA
FOC37_RS14470	COG4166	transmembrane transport
FOC37_RS14475	COG2866	Carboxypeptidase
FOC37_RS14480	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_RS14485	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC37_RS14495	COG5642	Protein of unknown function (DUF2384)
FOC37_RS14500	COG5654	RES domain protein
FOC37_RS14505	COG3768	UPF0283 membrane protein
FOC37_RS14510	COG3106	COG3106 Predicted ATPase
FOC37_RS14520	COG1983	PspC domain protein
FOC37_RS14530	COG1842	Phage shock protein A
FOC37_RS14535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC37_RS14550	COG4166	transmembrane transport
FOC37_RS14555	COG4168	peptide transport system, permease
FOC37_RS14560	COG4171	peptide transport system, permease
FOC37_RS14570	COG4172	Belongs to the ABC transporter superfamily
FOC37_RS14575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC37_RS14575	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC37_RS14580	COG0583	DNA-binding transcription factor activity
FOC37_RS14585	COG3104	oligopeptide transport
FOC37_RS14605	COG0625	glutathione transferase activity
FOC37_RS14615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC37_RS14625	COG3895	Periplasmic Protein
FOC37_RS14630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOC37_RS14635	COG3133	Outer membrane lipoprotein
FOC37_RS14640	COG1846	Transcriptional regulator
FOC37_RS14650	COG1566	PFAM secretion protein HlyD family protein
FOC37_RS14655	COG1289	transmembrane transporter activity
FOC37_RS14660	COG4989	oxidoreductase activity
FOC37_RS14665	COG3313	Fe-S protein
FOC37_RS14670	COG2194	sulfuric ester hydrolase activity
FOC37_RS14675	COG1309	transcriptional regulator
FOC37_RS14680	COG1902	pentaerythritol trinitrate reductase activity
FOC37_RS14685	COG0346	lactoylglutathione lyase activity
FOC37_RS14690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC37_RS14695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOC37_RS14700	COG0791	NLP P60 protein
FOC37_RS14715	COG1609	Transcriptional regulator
FOC37_RS14720	COG0583	DNA-binding transcription factor activity
FOC37_RS14725	COG2814	Major facilitator Superfamily
FOC37_RS14730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC37_RS14735	COG0307	riboflavin synthase, alpha
FOC37_RS14740	COG0534	Mate efflux family protein
FOC37_RS14775	COG1388	LysM domain
FOC37_RS14775	COG1376	ErfK ybiS ycfS ynhG family protein
FOC37_RS14780	COG2166	iron-sulfur cluster assembly
FOC37_RS14790	COG0719	Fe-S assembly protein
FOC37_RS14795	COG0396	ATPase activity
FOC37_RS14800	COG0719	Fe-S assembly protein
FOC37_RS14805	COG0316	Belongs to the HesB IscA family
FOC37_RS14810	COG2050	protein possibly involved in aromatic compounds catabolism
FOC37_RS14815	COG0277	FAD linked oxidase domain protein
FOC37_RS14815	COG0247	lactate metabolic process
FOC37_RS14820	COG0628	permease
FOC37_RS14830	COG0574	Belongs to the PEP-utilizing enzyme family
FOC37_RS14830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC37_RS14835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOC37_RS14840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC37_RS14855	COG3720	iron ion transport
FOC37_RS14860	COG4558	Periplasmic binding protein
FOC37_RS14870	COG0095	Lipoate-protein ligase
FOC37_RS14875	COG0791	NLP P60 protein
FOC37_RS14880	COG2076	Multidrug Resistance protein
FOC37_RS14885	COG2076	Multidrug Resistance protein
FOC37_RS14890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOC37_RS14895	COG0726	polysaccharide deacetylase
FOC37_RS14905	COG0463	Glycosyl transferase, family 2
FOC37_RS14910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC37_RS14915	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FOC37_RS14920	COG0386	Belongs to the glutathione peroxidase family
FOC37_RS14925	COG4139	cobalamin transport
FOC37_RS14935	COG0776	regulation of translation
FOC37_RS14955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC37_RS14960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC37_RS14970	COG4249	Peptidase C14 caspase catalytic subunit p20
FOC37_RS14975	COG1811	Na channel or pump
FOC37_RS14980	COG1414	Transcriptional regulator
FOC37_RS14985	COG1129	ABC transporter
FOC37_RS14990	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS15010	COG1070	Carbohydrate kinase
FOC37_RS15015	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC37_RS15020	COG3623	hexulose-6-phosphate isomerase
FOC37_RS15050	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC37_RS15055	COG1121	(ABC) transporter
FOC37_RS15060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_RS15065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC37_RS15070	COG3001	Fructosamine kinase
FOC37_RS15075	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC37_RS15075	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC37_RS15080	COG1703	isobutyryl-CoA mutase activity
FOC37_RS15085	COG1024	Enoyl-CoA hydratase
FOC37_RS15090	COG0427	acetyl-CoA hydrolase
FOC37_RS15095	COG0583	DNA-binding transcription factor activity
FOC37_RS15105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_RS15110	COG1917	Cupin 2, conserved barrel domain protein
FOC37_RS15120	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS15130	COG1175	transmembrane transport
FOC37_RS15135	COG0395	ABC-type sugar transport system, permease component
FOC37_RS15140	COG3842	ATPase activity
FOC37_RS15150	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_RS15155	COG1988	membrane-bound metal-dependent
FOC37_RS15160	COG1823	symporter activity
FOC37_RS15165	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC37_RS15175	COG0823	Involved in the tonB-independent uptake of proteins
FOC37_RS15180	COG2814	Major facilitator Superfamily
FOC37_RS15185	COG0501	Belongs to the peptidase M48B family
FOC37_RS15190	COG0793	Belongs to the peptidase S41A family
FOC37_RS15200	COG1956	GAF domain-containing protein
FOC37_RS15205	COG2995	paraquat-inducible protein a
FOC37_RS15210	COG3008	intermembrane lipid transfer
FOC37_RS15220	COG2814	Major facilitator Superfamily
FOC37_RS15225	COG5001	Diguanylate cyclase
FOC37_RS15225	COG4251	negative regulation of phosphorylation
FOC37_RS15225	COG3706	GGDEF domain
FOC37_RS15225	COG2203	Gaf domain
FOC37_RS15255	COG0625	glutathione transferase activity
FOC37_RS15275	COG0697	spore germination
FOC37_RS15285	COG1187	pseudouridine synthase activity
FOC37_RS15290	COG0668	transmembrane transport
FOC37_RS15315	COG1276	copper resistance
FOC37_RS15320	COG2372	response to copper ion
FOC37_RS15325	COG1528	Iron-storage protein
FOC37_RS15340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC37_RS15345	COG1770	oligopeptidase
FOC37_RS15355	COG3097	Belongs to the UPF0267 family
FOC37_RS15360	COG3141	response to X-ray
FOC37_RS15365	COG0513	Belongs to the DEAD box helicase family
FOC37_RS15370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOC37_RS15375	COG3140	Belongs to the UPF0181 family
FOC37_RS15385	COG0494	nUDIX hydrolase
FOC37_RS15390	COG1760	l-serine dehydratase
FOC37_RS15395	COG1253	flavin adenine dinucleotide binding
FOC37_RS15400	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS15400	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS15405	COG3715	PTS system
FOC37_RS15410	COG3716	PTS system mannose fructose sorbose family IID component
FOC37_RS15415	COG4811	Protein of unknown function (DUF986)
FOC37_RS15420	COG1971	Probably functions as a manganese efflux pump
FOC37_RS15430	COG5001	Diguanylate cyclase
FOC37_RS15430	COG5002	protein histidine kinase activity
FOC37_RS15430	COG3447	MASE1 domain protein
FOC37_RS15440	COG2226	methyltransferase
FOC37_RS15445	COG0768	penicillin binding
FOC37_RS15450	COG1496	oxidoreductase activity
FOC37_RS15470	COG1113	amino acid transport
FOC37_RS15505	COG2207	Transcriptional regulator
FOC37_RS15525	COG1132	(ABC) transporter
FOC37_RS15535	COG3706	GGDEF domain
FOC37_RS15535	COG2203	Gaf domain
FOC37_RS15535	COG5001	Diguanylate cyclase
FOC37_RS15535	COG4251	negative regulation of phosphorylation
FOC37_RS15550	COG3755	Protein conserved in bacteria
FOC37_RS15560	COG0697	spore germination
FOC37_RS15570	COG1733	regulation of RNA biosynthetic process
FOC37_RS15575	COG0702	epimerase
FOC37_RS15580	COG2873	o-acetylhomoserine
FOC37_RS15590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC37_RS15600	COG0840	transmembrane signaling receptor activity
FOC37_RS15605	COG3397	chitin binding
FOC37_RS15625	COG0538	isocitrate dehydrogenase activity
FOC37_RS15630	COG1187	pseudouridine synthase activity
FOC37_RS15640	COG0482	sulfurtransferase activity
FOC37_RS15645	COG2915	High frequency lysogenization protein hflD homolog
FOC37_RS15650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC37_RS15660	COG0745	RESPONSE REGULATOR receiver
FOC37_RS15670	COG2850	peptidyl-arginine hydroxylation
FOC37_RS15685	COG1940	carbohydrate kinase activity
FOC37_RS15690	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC37_RS15700	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC37_RS15705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC37_RS15710	COG3134	Outer membrane lipoprotein
FOC37_RS15715	COG1252	NADH dehydrogenase
FOC37_RS15720	COG3150	esterase
FOC37_RS15735	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FOC37_RS15740	COG5633	Lipoprotein
FOC37_RS15745	COG0537	adenosine 5'-monophosphoramidase activity
FOC37_RS15755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS15755	COG1263	PTS System
FOC37_RS15760	COG0084	hydrolase, TatD family'
FOC37_RS15765	COG0470	DNA polymerase III
FOC37_RS15770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOC37_RS15775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC37_RS15780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC37_RS15785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC37_RS15800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC37_RS15810	COG0416	fatty acid biosynthetic process
FOC37_RS15815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC37_RS15820	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC37_RS15830	COG0564	pseudouridine synthase activity
FOC37_RS15835	COG1530	ribonuclease E activity
FOC37_RS15840	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOC37_RS15845	COG0418	dihydroorotase activity
FOC37_RS15875	COG0628	permease
FOC37_RS15910	COG1560	Kdo2-lipid A biosynthetic process
FOC37_RS15915	COG2259	Doxx family
FOC37_RS15920	COG2814	Major facilitator Superfamily
FOC37_RS15940	COG5645	(Lipo)protein
FOC37_RS15945	COG2943	transferase activity, transferring hexosyl groups
FOC37_RS15950	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FOC37_RS15980	COG3916	Acyl-homoserine-lactone synthase
FOC37_RS15985	COG2771	luxR family
FOC37_RS15995	COG0531	amino acid
FOC37_RS16000	COG0076	glutamate decarboxylase activity
FOC37_RS16020	COG1470	cell adhesion involved in biofilm formation
FOC37_RS16020	COG1388	LysM domain
FOC37_RS16035	COG0549	Belongs to the carbamate kinase family
FOC37_RS16045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC37_RS16050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC37_RS16055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOC37_RS16060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC37_RS16065	COG3257	ureidoglycine aminohydrolase activity
FOC37_RS16070	COG1929	Belongs to the glycerate kinase type-1 family
FOC37_RS16075	COG2233	PERMEase
FOC37_RS16085	COG1953	Uracil, thiamine, allantoin
FOC37_RS16090	COG2084	Dehydrogenase
FOC37_RS16095	COG3622	Belongs to the hyi family
FOC37_RS16100	COG3960	tartronate-semialdehyde synthase activity
FOC37_RS16115	COG0583	DNA-binding transcription factor activity
FOC37_RS16125	COG2205	protein histidine kinase activity
FOC37_RS16125	COG4999	Histidine kinase
FOC37_RS16125	COG3850	Histidine kinase
FOC37_RS16125	COG3437	response regulator, receiver
FOC37_RS16130	COG3250	beta-galactosidase activity
FOC37_RS16150	COG1215	transferase activity, transferring glycosyl groups
FOC37_RS16160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC37_RS16165	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC37_RS16170	COG0745	RESPONSE REGULATOR receiver
FOC37_RS16180	COG0058	SHG alpha-glucan phosphorylase activity
FOC37_RS16210	COG3121	Chaperone
FOC37_RS16225	COG3121	Chaperone
FOC37_RS16230	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FOC37_RS16255	COG2920	part of a sulfur-relay system
FOC37_RS16260	COG1254	Belongs to the acylphosphatase family
FOC37_RS16270	COG3785	DNA binding
FOC37_RS16275	COG1832	CoA-binding protein
FOC37_RS16290	COG0210	DNA helicase
FOC37_RS16295	COG3304	Inner membrane component domain
FOC37_RS16300	COG1289	transmembrane transporter activity
FOC37_RS16305	COG3070	regulator of competence-specific genes
FOC37_RS16310	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FOC37_RS16320	COG3120	sequence-specific DNA binding
FOC37_RS16325	COG1067	ATP-dependent peptidase activity
FOC37_RS16330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC37_RS16340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC37_RS16345	COG3130	regulation of translation
FOC37_RS16350	COG3009	Protein conserved in bacteria
FOC37_RS16355	COG3008	intermembrane lipid transfer
FOC37_RS16355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOC37_RS16360	COG2995	paraquat-inducible protein a
FOC37_RS16365	COG0488	(ABC) transporter
FOC37_RS16370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC37_RS16370	COG0116	Belongs to the methyltransferase superfamily
FOC37_RS16375	COG3217	Mosc domain protein beta barrel domain protein
FOC37_RS16375	COG0633	Ferredoxin
FOC37_RS16385	COG0167	dihydroorotate dehydrogenase activity
FOC37_RS16390	COG0308	aminopeptidase N
FOC37_RS16395	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC37_RS16400	COG0017	Asparaginyl-tRNA synthetase
FOC37_RS16410	COG1448	Aminotransferase
FOC37_RS16415	COG2200	EAL domain
FOC37_RS16420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC37_RS16425	COG3108	Peptidase M15
FOC37_RS16430	COG2989	Protein conserved in bacteria
FOC37_RS16435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOC37_RS16445	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FOC37_RS16450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC37_RS16455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC37_RS16460	COG3173	Aminoglycoside phosphotransferase
FOC37_RS16475	COG2835	tetraacyldisaccharide 4'-kinase activity
FOC37_RS16480	COG1278	Cold shock
FOC37_RS16490	COG5383	Protein conserved in bacteria
FOC37_RS16495	COG1663	tetraacyldisaccharide 4'-kinase activity
FOC37_RS16505	COG0658	competence protein
FOC37_RS16505	COG2333	competence protein COMEC
FOC37_RS16510	COG0776	regulation of translation
FOC37_RS16515	COG0539	negative regulation of cytoplasmic translation
FOC37_RS16525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC37_RS16535	COG0252	asparaginase activity
FOC37_RS16540	COG1944	ATP diphosphatase activity
FOC37_RS16545	COG2116	formate transmembrane transporter activity
FOC37_RS16550	COG1882	Formate acetyltransferase
FOC37_RS16555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC37_RS16560	COG2814	Major facilitator Superfamily
FOC37_RS16565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC37_RS16570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC37_RS16575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC37_RS16580	COG3107	peptidoglycan biosynthetic process
FOC37_RS16580	COG1674	ftsk spoiiie
FOC37_RS16590	COG0492	ferredoxin-NADP+ reductase activity
FOC37_RS16600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC37_RS16610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC37_RS16615	COG0542	response to heat
FOC37_RS16620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOC37_RS16625	COG1278	Cold shock
FOC37_RS16635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS16640	COG2990	Protein conserved in bacteria
FOC37_RS16645	COG3593	DNA synthesis involved in DNA repair
FOC37_RS16650	COG2431	L-lysine efflux transmembrane transporter activity
FOC37_RS16655	COG1151	hydroxylamine reductase activity
FOC37_RS16660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC37_RS16665	COG0028	Belongs to the TPP enzyme family
FOC37_RS16675	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOC37_RS16680	COG0702	epimerase
FOC37_RS16685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC37_RS16695	COG1126	abc transporter atp-binding protein
FOC37_RS16700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS16705	COG4215	(ABC) transporter
FOC37_RS16710	COG4160	amino acid transport
FOC37_RS16715	COG1414	Transcriptional regulator
FOC37_RS16720	COG1012	belongs to the aldehyde dehydrogenase family
FOC37_RS16725	COG1454	alcohol dehydrogenase
FOC37_RS16730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC37_RS16735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS16750	COG1177	transmembrane transport
FOC37_RS16755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC37_RS16760	COG3842	ATPase activity
FOC37_RS16765	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC37_RS16785	COG0569	domain protein
FOC37_RS16785	COG2985	domain, Protein
FOC37_RS16795	COG0671	phosphoesterase, PA-phosphatase related
FOC37_RS16805	COG1349	DNA-binding transcription factor activity
FOC37_RS16810	COG0814	amino acid
FOC37_RS16815	COG1760	l-serine dehydratase
FOC37_RS16820	COG1686	Belongs to the peptidase S11 family
FOC37_RS16830	COG0626	cystathionine gamma-synthase activity
FOC37_RS16835	COG2011	ABC-type metal ion transport system permease component
FOC37_RS16860	COG0625	glutathione transferase activity
FOC37_RS16865	COG4771	TonB-dependent receptor
FOC37_RS16870	COG0833	amino acid
FOC37_RS16875	COG0583	DNA-binding transcription factor activity
FOC37_RS16880	COG2855	membrane
FOC37_RS16885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOC37_RS16890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC37_RS16890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC37_RS16890	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOC37_RS16895	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC37_RS16910	COG3005	denitrification pathway
FOC37_RS16915	COG0243	molybdopterin cofactor binding
FOC37_RS16920	COG1349	DNA-binding transcription factor activity
FOC37_RS16930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS16940	COG3716	PTS system mannose fructose sorbose family IID component
FOC37_RS16945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS16950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC37_RS16955	COG2222	sugar isomerase
FOC37_RS16980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC37_RS16995	COG0246	Mannitol dehydrogenase
FOC37_RS17000	COG2186	Transcriptional regulator
FOC37_RS17005	COG0523	cobalamin synthesis protein
FOC37_RS17010	COG0671	phosphoesterase, PA-phosphatase related
FOC37_RS17015	COG0791	NLP P60 protein
FOC37_RS17020	COG2200	EAL domain
FOC37_RS17025	COG4166	transmembrane transport
FOC37_RS17030	COG4174	ABC transporter (Permease)
FOC37_RS17035	COG4239	(ABC) transporter, permease
FOC37_RS17040	COG4172	Belongs to the ABC transporter superfamily
FOC37_RS17055	COG2814	Major facilitator Superfamily
FOC37_RS17060	COG1187	pseudouridine synthase activity
FOC37_RS17065	COG1061	Type III restriction enzyme res subunit
FOC37_RS17075	COG3081	Nucleoid-associated protein
FOC37_RS17080	COG3082	Protein of unknown function (DUF1414)
FOC37_RS17115	COG3338	carbonate dehydratase activity
FOC37_RS17120	COG2723	6-phospho-beta-galactosidase activity
FOC37_RS17125	COG2190	(PTS) system
FOC37_RS17125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS17125	COG1263	PTS System
FOC37_RS17175	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC37_RS17190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_RS17190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_RS17195	COG0583	DNA-binding transcription factor activity
FOC37_RS17200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC37_RS17200	COG1648	precorrin-2 dehydrogenase activity
FOC37_RS17210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC37_RS17220	COG4865	methylaspartate mutase activity
FOC37_RS17225	COG3799	methylaspartate ammonia-lyase activity
FOC37_RS17240	COG1301	dicarboxylic acid transport
FOC37_RS17255	COG3188	usher protein
FOC37_RS17315	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC37_RS17335	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOC37_RS17340	COG2223	nitrite transmembrane transporter activity
FOC37_RS17345	COG0642	Histidine kinase
FOC37_RS17345	COG2198	Histidine kinase
FOC37_RS17355	COG0784	Response regulator, receiver
FOC37_RS17355	COG2205	protein histidine kinase activity
FOC37_RS17365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC37_RS17370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC37_RS17380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC37_RS17385	COG4574	serine-type endopeptidase inhibitor activity
FOC37_RS17420	COG0814	amino acid
FOC37_RS17440	COG1441	menaquinone biosynthetic process
FOC37_RS17445	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC37_RS17455	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC37_RS17460	COG1169	isochorismate synthase
FOC37_RS17465	COG4575	ribosome binding
FOC37_RS17470	COG0129	dihydroxy-acid dehydratase activity
FOC37_RS17475	COG4702	Belongs to the UPF0303 family
FOC37_RS17485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC37_RS17490	COG1609	Transcriptional regulator
FOC37_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS17500	COG3265	gluconokinase activity
FOC37_RS17505	COG2731	YhcH YjgK YiaL family protein
FOC37_RS17520	COG1007	ATP synthesis coupled electron transport
FOC37_RS17525	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_RS17530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC37_RS17535	COG0713	ATP synthesis coupled electron transport
FOC37_RS17540	COG0839	Belongs to the complex I subunit 6 family
FOC37_RS17545	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_RS17550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOC37_RS17555	COG1034	ATP synthesis coupled electron transport
FOC37_RS17570	COG0649	NAD binding
FOC37_RS17570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_RS17575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC37_RS17585	COG0583	DNA-binding transcription factor activity
FOC37_RS17595	COG0436	Aminotransferase
FOC37_RS17605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FOC37_RS17610	COG0490	domain, Protein
FOC37_RS17610	COG0471	metal ion transport
FOC37_RS17615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_RS17625	COG3092	negative regulation of chromosome organization
FOC37_RS17635	COG0280	phosphate acetyltransferase
FOC37_RS17635	COG0857	belongs to the CobB CobQ family
FOC37_RS17640	COG1609	Transcriptional regulator
FOC37_RS17645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS17655	COG3037	sugar-specific permease SgaT UlaA
FOC37_RS17660	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC37_RS17665	COG0622	Phosphoesterase
FOC37_RS17675	COG1090	epimerase
FOC37_RS17685	COG4598	ABC transporter
FOC37_RS17695	COG4215	(ABC) transporter
FOC37_RS17700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC37_RS17710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC37_RS17715	COG1286	toxin biosynthetic process
FOC37_RS17720	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FOC37_RS17725	COG0285	dihydrofolate synthase activity
FOC37_RS17735	COG0586	Pfam SNARE associated Golgi protein
FOC37_RS17745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC37_RS17770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC37_RS17775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC37_RS17800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC37_RS17810	COG1794	racemase activity, acting on amino acids and derivatives
FOC37_RS17820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC37_RS17825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC37_RS17825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOC37_RS17835	COG3101	peptidyl-lysine hydroxylation
FOC37_RS17840	COG0730	response to heat
FOC37_RS17850	COG5301	cellulose 1,4-beta-cellobiosidase activity
FOC37_RS17900	COG0741	lytic transglycosylase activity
FOC37_RS17900	COG1196	nuclear chromosome segregation
FOC37_RS17900	COG0739	heme binding
FOC37_RS18010	COG3772	lysozyme
FOC37_RS18030	COG0305	Participates in initiation and elongation during chromosome replication
FOC37_RS18035	COG1484	DNA-dependent DNA replication
FOC37_RS18050	COG4197	protein conserved in bacteria, prophage-related
FOC37_RS18160	COG0582	viral genome integration into host DNA
FOC37_RS18165	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FOC37_RS18170	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC37_RS18175	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC37_RS18180	COG2840	Smr protein MutS2
FOC37_RS18185	COG2062	phosphohistidine phosphatase, SixA
FOC37_RS18190	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC37_RS18190	COG1024	Enoyl-CoA hydratase
FOC37_RS18195	COG0183	Belongs to the thiolase family
FOC37_RS18200	COG3691	Protein conserved in bacteria
FOC37_RS18215	COG3088	subunit of a heme lyase
FOC37_RS18215	COG4235	cytochrome complex assembly
FOC37_RS18220	COG4235	cytochrome complex assembly
FOC37_RS18220	COG3088	subunit of a heme lyase
FOC37_RS18225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC37_RS18230	COG1138	Cytochrome C-type biogenesis protein
FOC37_RS18235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FOC37_RS18240	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC37_RS18245	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC37_RS18250	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC37_RS18265	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC37_RS18275	COG0582	viral genome integration into host DNA
FOC37_RS18375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC37_RS18430	COG1695	Transcriptional regulator
FOC37_RS18440	COG2723	6-phospho-beta-galactosidase activity
FOC37_RS18445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC37_RS18445	COG1263	PTS System
FOC37_RS18450	COG1609	Transcriptional regulator
FOC37_RS18455	COG1757	Na H antiporter
FOC37_RS18460	COG2353	YceI-like domain
FOC37_RS18465	COG3038	cytochrome b561
FOC37_RS18475	COG0626	cystathionine gamma-synthase activity
FOC37_RS18495	COG1127	ABC transporter
FOC37_RS18500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC37_RS18520	COG0531	amino acid
FOC37_RS18525	COG2951	lytic endotransglycosylase activity
FOC37_RS18555	COG2723	6-phospho-beta-galactosidase activity
FOC37_RS18570	COG0243	molybdopterin cofactor binding
FOC37_RS18575	COG0437	4 iron, 4 sulfur cluster binding
FOC37_RS18580	COG3302	dmso reductase anchor subunit
FOC37_RS18585	COG3381	protein complex oligomerization
FOC37_RS18595	COG1598	PFAM Uncharacterised protein family UPF0150
FOC37_RS18605	COG3038	cytochrome b561
FOC37_RS18610	COG0436	Aminotransferase
FOC37_RS18625	COG3275	phosphorelay sensor kinase activity
FOC37_RS18630	COG3279	Response regulator of the LytR AlgR family
FOC37_RS18635	COG2223	nitrite transmembrane transporter activity
FOC37_RS18640	COG0837	glucose binding
FOC37_RS18655	COG0667	Aldo Keto reductase
FOC37_RS18665	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC37_RS18670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_RS18705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC37_RS18730	COG3530	Putative quorum-sensing-regulated virulence factor
FOC37_RS18735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC37_RS18745	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FOC37_RS18755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS18770	COG2205	protein histidine kinase activity
FOC37_RS18775	COG0745	RESPONSE REGULATOR receiver
FOC37_RS18780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS18850	COG4208	sulfate ABC transporter
FOC37_RS18855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOC37_RS18860	COG4150	thiosulfate binding
FOC37_RS18865	COG2837	iron assimilation
FOC37_RS18875	COG3111	PFAM Bacterial OB fold (BOF) protein
FOC37_RS18955	COG2826	transposase and inactivated derivatives, IS30 family
FOC37_RS18985	COG0456	acetyltransferase
FOC37_RS18990	COG0408	coproporphyrinogen oxidase activity
FOC37_RS18995	COG1671	Belongs to the UPF0178 family
FOC37_RS19020	COG3005	denitrification pathway
FOC37_RS19025	COG3043	anaerobic respiration
FOC37_RS19030	COG0243	molybdopterin cofactor binding
FOC37_RS19035	COG3062	negative regulation of establishment of protein localization
FOC37_RS19040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS19040	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS19045	COG2197	response regulator
FOC37_RS19055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_RS19100	COG1393	Belongs to the ArsC family
FOC37_RS19105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC37_RS19110	COG1876	peptidase activity
FOC37_RS19120	COG0400	carboxylic ester hydrolase activity
FOC37_RS19130	COG1444	tRNA N-acetyltransferase activity
FOC37_RS19140	COG2321	neutral zinc metallopeptidase
FOC37_RS19150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOC37_RS19155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC37_RS19160	COG2716	regulation of RNA biosynthetic process
FOC37_RS19165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC37_RS19170	COG0628	permease
FOC37_RS19175	COG4783	chaperone-mediated protein folding
FOC37_RS19180	COG1393	Belongs to the ArsC family
FOC37_RS19185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC37_RS19190	COG2233	PERMEase
FOC37_RS19200	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC37_RS19205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC37_RS19210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC37_RS19225	COG0581	inorganic phosphate transmembrane transporter activity
FOC37_RS19230	COG0573	inorganic phosphate transmembrane transporter activity
FOC37_RS19235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC37_RS19240	COG0248	Ppx GppA phosphatase
FOC37_RS19250	COG2239	Acts as a magnesium transporter
FOC37_RS19255	COG5002	protein histidine kinase activity
FOC37_RS19255	COG5001	Diguanylate cyclase
FOC37_RS19255	COG3447	MASE1 domain protein
FOC37_RS19260	COG0443	Heat shock 70 kDa protein
FOC37_RS19265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS19275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_RS19280	COG2205	protein histidine kinase activity
FOC37_RS19285	COG0745	RESPONSE REGULATOR receiver
FOC37_RS19290	COG3422	double-strand break repair
FOC37_RS19295	COG0826	peptidase U32
FOC37_RS19300	COG1597	lipid kinase activity
FOC37_RS19305	COG3730	PTS system glucitol sorbitol-specific
FOC37_RS19320	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS19325	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS19330	COG1349	DNA-binding transcription factor activity
FOC37_RS19350	COG0351	phosphomethylpyrimidine kinase
FOC37_RS19370	COG0519	Catalyzes the synthesis of GMP from XMP
FOC37_RS19370	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC37_RS19375	COG0517	IMP dehydrogenase activity
FOC37_RS19375	COG0516	GMP reductase activity
FOC37_RS19385	COG1645	bacterial-type flagellum-dependent swarming motility
FOC37_RS19400	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC37_RS19405	COG2976	Protein conserved in bacteria
FOC37_RS19420	COG1426	Protein conserved in bacteria
FOC37_RS19430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC37_RS19445	COG4953	penicillin-binding protein 1C
FOC37_RS19450	COG2373	Large extracellular alpha-helical protein
FOC37_RS19455	COG3468	outer membrane autotransporter barrel domain protein
FOC37_RS19470	COG2975	iron-sulfur cluster assembly
FOC37_RS19475	COG0633	Ferredoxin
FOC37_RS19480	COG0443	Heat shock 70 kDa protein
FOC37_RS19485	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC37_RS19495	COG0822	iron-sulfur transferase activity
FOC37_RS19505	COG1959	2 iron, 2 sulfur cluster binding
FOC37_RS19510	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOC37_RS19520	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC37_RS19525	COG3683	transport system, periplasmic component
FOC37_RS19530	COG3711	transcriptional antiterminator
FOC37_RS19535	COG2814	Major facilitator Superfamily
FOC37_RS19545	COG1017	nitric oxide dioxygenase activity
FOC37_RS19545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC37_RS19550	COG2188	Transcriptional regulator
FOC37_RS19560	COG3457	Alanine racemase
FOC37_RS19565	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FOC37_RS19580	COG0347	Belongs to the P(II) protein family
FOC37_RS19585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC37_RS19585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC37_RS19590	COG2204	response regulator
FOC37_RS19595	COG3170	Tfp pilus assembly protein FimV
FOC37_RS19600	COG2205	protein histidine kinase activity
FOC37_RS19615	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC37_RS19630	COG0560	Phosphoserine phosphatase
FOC37_RS19645	COG1737	Transcriptional regulator
FOC37_RS19650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC37_RS19655	COG0736	holo-[acyl-carrier-protein] synthase activity
FOC37_RS19660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOC37_RS19665	COG1381	Involved in DNA repair and RecF pathway recombination
FOC37_RS19670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC37_RS19685	COG0481	GTPase activity
FOC37_RS19695	COG3086	response to oxidative stress
FOC37_RS19700	COG3026	antisigma factor binding
FOC37_RS19705	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FOC37_RS19715	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC37_RS19720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC37_RS19725	COG0513	Belongs to the DEAD box helicase family
FOC37_RS19740	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FOC37_RS19745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC37_RS19750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC37_RS19755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC37_RS19760	COG0497	DNA recombination
FOC37_RS19765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC37_RS19775	COG2867	negative regulation of translational initiation
FOC37_RS19780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC37_RS19790	COG0582	viral genome integration into host DNA
FOC37_RS19825	COG3394	polysaccharide catabolic process
FOC37_RS19830	COG1917	Cupin 2, conserved barrel domain protein
FOC37_RS19830	COG2169	Transcriptional regulator
FOC37_RS19835	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC37_RS19840	COG2723	6-phospho-beta-galactosidase activity
FOC37_RS19845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_RS19850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC37_RS19855	COG2133	pyrroloquinoline quinone binding
FOC37_RS19860	COG0667	Aldo Keto reductase
FOC37_RS19875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC37_RS19885	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FOC37_RS19890	COG4413	Urea transporter
FOC37_RS19900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FOC37_RS19905	COG0830	nickel cation binding
FOC37_RS19910	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FOC37_RS19915	COG0804	urea catabolic process
FOC37_RS19925	COG0831	urea catabolic process
FOC37_RS19930	COG1124	(ABC) transporter
FOC37_RS19940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_RS19945	COG0601	transmembrane transport
FOC37_RS19975	COG1278	Cold shock
FOC37_RS19995	COG3708	Transcriptional regulator
FOC37_RS19995	COG2207	Transcriptional regulator
FOC37_RS20010	COG4575	ribosome binding
FOC37_RS20020	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOC37_RS20025	COG1780	Probably involved in ribonucleotide reductase function
FOC37_RS20035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC37_RS20045	COG4176	ABC-type proline glycine betaine transport system permease component
FOC37_RS20050	COG2113	Glycine betaine
FOC37_RS20090	COG2226	methyltransferase
FOC37_RS20095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC37_RS20100	COG1388	LysM domain
FOC37_RS20100	COG0741	lytic transglycosylase activity
FOC37_RS20105	COG3021	interspecies interaction between organisms
FOC37_RS20110	COG2814	Major facilitator Superfamily
FOC37_RS20115	COG0583	DNA-binding transcription factor activity
FOC37_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS20170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC37_RS20185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC37_RS20245	COG0542	response to heat
FOC37_RS20255	COG0564	pseudouridine synthase activity
FOC37_RS20260	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC37_RS20265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC37_RS20270	COG1605	Chorismate mutase
FOC37_RS20270	COG0077	Prephenate dehydratase
FOC37_RS20275	COG1605	Chorismate mutase
FOC37_RS20275	COG0287	Prephenate dehydrogenase
FOC37_RS20280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOC37_RS20285	COG3279	Response regulator of the LytR AlgR family
FOC37_RS20290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC37_RS20295	COG3137	Salt-induced outer membrane protein
FOC37_RS20300	COG0335	large ribosomal subunit rRNA binding
FOC37_RS20305	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC37_RS20315	COG0228	four-way junction DNA binding
FOC37_RS20320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC37_RS20325	COG4137	Cytochrome C assembly protein
FOC37_RS20330	COG4536	flavin adenine dinucleotide binding
FOC37_RS20335	COG1854	S-ribosylhomocysteine lyase activity
FOC37_RS20340	COG2918	glutathione biosynthetic process
FOC37_RS20345	COG1238	metal cluster binding
FOC37_RS20350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC37_RS20385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOC37_RS20390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC37_RS20395	COG2137	regulation of response to DNA damage stimulus
FOC37_RS20400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOC37_RS20425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOC37_RS20430	COG3958	Transketolase
FOC37_RS20435	COG3959	Transketolase, thiamine diphosphate binding domain
FOC37_RS20440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS20445	COG1129	ABC transporter
FOC37_RS20455	COG1879	ABC-type sugar transport system periplasmic component
FOC37_RS20470	COG3381	protein complex oligomerization
FOC37_RS20475	COG3302	dmso reductase anchor subunit
FOC37_RS20480	COG0437	4 iron, 4 sulfur cluster binding
FOC37_RS20485	COG0243	molybdopterin cofactor binding
FOC37_RS20490	COG1454	alcohol dehydrogenase
FOC37_RS20495	COG0235	Class ii aldolase
FOC37_RS20500	COG0738	Major facilitator superfamily
FOC37_RS20510	COG1070	Carbohydrate kinase
FOC37_RS20520	COG1349	DNA-binding transcription factor activity
FOC37_RS20525	COG0235	Class ii aldolase
FOC37_RS20530	COG1349	DNA-binding transcription factor activity
FOC37_RS20545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS20550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS20555	COG3623	hexulose-6-phosphate isomerase
FOC37_RS20560	COG1070	Carbohydrate kinase
FOC37_RS20565	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_RS20565	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC37_RS20580	COG4177	L-phenylalanine transmembrane transporter activity
FOC37_RS20585	COG1137	ATPase activity
FOC37_RS20590	COG0410	ABC transporter
FOC37_RS20645	COG0640	Transcriptional regulator
FOC37_RS20650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC37_RS20655	COG3158	transport of potassium into the cell
FOC37_RS20660	COG3048	D-serine ammonia-lyase activity
FOC37_RS20665	COG2610	gluconate transmembrane transporter activity
FOC37_RS20670	COG0583	DNA-binding transcription factor activity
FOC37_RS20675	COG4608	Belongs to the ABC transporter superfamily
FOC37_RS20685	COG0601	transmembrane transport
FOC37_RS20695	COG4948	Mandelate Racemase Muconate Lactonizing
FOC37_RS20700	COG1028	Short-chain dehydrogenase reductase Sdr
FOC37_RS20720	COG1538	Outer membrane efflux protein
FOC37_RS20725	COG1136	(ABC) transporter
FOC37_RS20725	COG0577	efflux transmembrane transporter activity
FOC37_RS20730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS20745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC37_RS20760	COG3539	Fimbrial protein
FOC37_RS20765	COG3539	Fimbrial protein
FOC37_RS20780	COG3121	Chaperone
FOC37_RS20785	COG3188	usher protein
FOC37_RS20810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC37_RS20815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC37_RS20820	COG4942	peptidase
FOC37_RS20820	COG1388	LysM domain
FOC37_RS20825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOC37_RS20830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOC37_RS20835	COG0585	pseudouridine synthase activity
FOC37_RS20840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC37_RS20850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOC37_RS20860	COG0765	amino acid transport
FOC37_RS20875	COG0529	Catalyzes the synthesis of activated sulfate
FOC37_RS20880	COG2895	sulfate adenylyltransferase (ATP) activity
FOC37_RS20885	COG0175	sulfate reduction
FOC37_RS20890	COG1648	precorrin-2 dehydrogenase activity
FOC37_RS20890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC37_RS20895	COG2234	aminopeptidase activity
FOC37_RS20910	COG0175	sulfate reduction
FOC37_RS20915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC37_RS20920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOC37_RS20925	COG0720	synthase
FOC37_RS20930	COG0602	queuosine metabolic process
FOC37_RS20940	COG0148	phosphopyruvate hydratase activity
FOC37_RS20945	COG0504	CTP synthase activity
FOC37_RS20950	COG3956	TIGRFAM MazG family protein
FOC37_RS20955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC37_RS20960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC37_RS20970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC37_RS20975	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOC37_RS20980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC37_RS20990	COG2860	membrane
FOC37_RS20995	COG0316	Belongs to the HesB IscA family
FOC37_RS21005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOC37_RS21015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC37_RS21020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC37_RS21025	COG1120	ATPase activity
FOC37_RS21030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC37_RS21035	COG1643	Atp-dependent helicase
FOC37_RS21040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC37_RS21045	COG1489	DNA binding
FOC37_RS21060	COG0617	tRNA 3'-terminal CCA addition
FOC37_RS21065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC37_RS21070	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC37_RS21075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC37_RS21085	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC37_RS21090	COG0726	polysaccharide deacetylase
FOC37_RS21095	COG0842	Transport permease protein
FOC37_RS21100	COG1131	(ABC) transporter
FOC37_RS21105	COG0288	reversible hydration of carbon dioxide
FOC37_RS21110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOC37_RS21115	COG2132	Multicopper oxidase
FOC37_RS21125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC37_RS21130	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC37_RS21140	COG3112	Uncharacterised protein family (UPF0231)
FOC37_RS21145	COG1049	propionate catabolic process, 2-methylcitrate cycle
FOC37_RS21160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC37_RS21165	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC37_RS21170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOC37_RS21175	COG2186	Transcriptional regulator
FOC37_RS21180	COG1113	amino acid transport
FOC37_RS21185	COG3725	Membrane protein required for beta-lactamase induction
FOC37_RS21200	COG4969	Belongs to the N-Me-Phe pilin family
FOC37_RS21205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC37_RS21210	COG1459	type II secretion system
FOC37_RS21215	COG0516	GMP reductase activity
FOC37_RS21230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOC37_RS21235	COG0494	nUDIX hydrolase
FOC37_RS21240	COG0653	protein targeting
FOC37_RS21260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC37_RS21265	COG0849	cell division
FOC37_RS21270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC37_RS21280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC37_RS21285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC37_RS21290	COG0772	Belongs to the SEDS family
FOC37_RS21300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC37_RS21305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC37_RS21310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC37_RS21315	COG0768	penicillin binding
FOC37_RS21320	COG3116	cell division
FOC37_RS21325	COG0275	rRNA processing
FOC37_RS21350	COG0028	Belongs to the TPP enzyme family
FOC37_RS21355	COG1022	Amp-dependent synthetase and ligase
FOC37_RS21360	COG0583	DNA-binding transcription factor activity
FOC37_RS21370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC37_RS21375	COG0473	3-isopropylmalate dehydrogenase activity
FOC37_RS21380	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC37_RS21395	COG3033	Beta-eliminating lyase
FOC37_RS21400	COG0814	amino acid
FOC37_RS21405	COG2814	Major facilitator Superfamily
FOC37_RS21410	COG1882	Formate acetyltransferase
FOC37_RS21415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC37_RS21420	COG4533	DNA binding
FOC37_RS21425	COG4143	(ABC) transporter
FOC37_RS21430	COG1178	ABC-type Fe3 transport system permease component
FOC37_RS21435	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FOC37_RS21440	COG0586	Pfam SNARE associated Golgi protein
FOC37_RS21450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC37_RS21455	COG0564	pseudouridine synthase activity
FOC37_RS21460	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOC37_RS21465	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOC37_RS21480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC37_RS21485	COG2967	ApaG domain
FOC37_RS21490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC37_RS21495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC37_RS21505	COG2966	Psort location CytoplasmicMembrane, score
FOC37_RS21510	COG1280	lysine exporter protein (LysE YggA)
FOC37_RS21515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC37_RS21530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC37_RS21535	COG1047	Peptidyl-prolyl cis-trans
FOC37_RS21540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC37_RS21545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC37_RS21550	COG0196	riboflavin kinase activity
FOC37_RS21565	COG0583	DNA-binding transcription factor activity
FOC37_RS21570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC37_RS21575	COG0484	heat shock protein binding
FOC37_RS21585	COG1584	GPR1 FUN34 yaaH family protein
FOC37_RS21600	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC37_RS21605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC37_RS21610	COG3022	response to hydroperoxide
FOC37_RS21620	COG0083	homoserine kinase activity
FOC37_RS21635	COG0745	RESPONSE REGULATOR receiver
FOC37_RS21640	COG3045	CreA protein
FOC37_RS21645	COG3708	Transcriptional regulator
FOC37_RS21645	COG2207	Transcriptional regulator
FOC37_RS21655	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC37_RS21660	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FOC37_RS21665	COG0741	lytic transglycosylase activity
FOC37_RS21670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC37_RS21680	COG2199	diguanylate cyclase activity
FOC37_RS21685	COG2885	chlorophyll binding
FOC37_RS21690	COG0488	(ABC) transporter
FOC37_RS21725	COG1454	alcohol dehydrogenase
FOC37_RS21740	COG0604	alcohol dehydrogenase
FOC37_RS21755	COG0560	Phosphoserine phosphatase
FOC37_RS21760	COG3726	membrane protein affecting hemolysin expression
FOC37_RS21765	COG3550	peptidyl-serine autophosphorylation
FOC37_RS21775	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC37_RS21780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC37_RS21790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC37_RS21795	COG0084	hydrolase, TatD family'
FOC37_RS21800	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC37_RS21810	COG2823	Periplasmic or secreted lipoprotein
FOC37_RS21815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC37_RS21820	COG0456	acetyltransferase
FOC37_RS21825	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FOC37_RS21835	COG0667	Aldo Keto reductase
FOC37_RS21925	COG2192	nodulation
FOC37_RS21935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC37_RS21935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC37_RS21935	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FOC37_RS21940	COG1461	Dihydroxyacetone kinase
FOC37_RS21945	COG2376	Dihydroxyacetone kinase
FOC37_RS21955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC37_RS21960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC37_RS21965	COG2235	arginine
FOC37_RS21980	COG0859	PFAM glycosyl transferase family 9
FOC37_RS21990	COG1070	Carbohydrate kinase
FOC37_RS21995	COG2390	Transcriptional regulator
FOC37_RS22000	COG1129	ABC transporter
FOC37_RS22005	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS22010	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC37_RS22015	COG1879	ABC-type sugar transport system periplasmic component
FOC37_RS22020	COG1830	Aldolase
FOC37_RS22030	COG0642	Histidine kinase
FOC37_RS22055	COG3272	Protein of unknown function (DUF1722)
FOC37_RS22075	COG3423	Transcriptional regulator
FOC37_RS22080	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_RS22195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC37_RS22235	COG0582	viral genome integration into host DNA
FOC37_RS22285	COG0795	lipopolysaccharide-transporting ATPase activity
FOC37_RS22290	COG0795	lipopolysaccharide-transporting ATPase activity
FOC37_RS22295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOC37_RS22300	COG2927	DNA polymerase III (CHI subunit)
FOC37_RS22315	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FOC37_RS22325	COG2731	YhcH YjgK YiaL family protein
FOC37_RS22335	COG0601	transmembrane transport
FOC37_RS22340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC37_RS22345	COG0444	Belongs to the ABC transporter superfamily
FOC37_RS22350	COG4608	Belongs to the ABC transporter superfamily
FOC37_RS22355	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC37_RS22360	COG0583	DNA-binding transcription factor activity
FOC37_RS22375	COG2188	Transcriptional regulator
FOC37_RS22380	COG3624	Phosphonate C-P lyase system protein PhnG
FOC37_RS22385	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FOC37_RS22390	COG3626	phosphonate metabolism
FOC37_RS22395	COG3627	carbon phosphorus lyase activity
FOC37_RS22400	COG4107	phosphonate C-P lyase system protein PhnK
FOC37_RS22405	COG4778	phosphonate C-P lyase system protein PhnL
FOC37_RS22410	COG3454	Phosphonate metabolism
FOC37_RS22415	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOC37_RS22420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC37_RS22425	COG0702	epimerase
FOC37_RS22430	COG3787	Belongs to the UPF0306 family
FOC37_RS22440	COG1982	Orn Lys Arg decarboxylase major
FOC37_RS22445	COG0531	amino acid
FOC37_RS22450	COG2827	Endonuclease containing a URI domain
FOC37_RS22455	COG3153	acetyltransferase
FOC37_RS22460	COG3154	lipid carrier protein
FOC37_RS22465	COG0826	peptidase U32
FOC37_RS22470	COG0826	peptidase U32
FOC37_RS22475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC37_RS22480	COG0513	Belongs to the DEAD box helicase family
FOC37_RS22495	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC37_RS22505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC37_RS22510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC37_RS22520	COG0195	Participates in both transcription termination and antitermination
FOC37_RS22540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC37_RS22550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC37_RS22560	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOC37_RS22565	COG1534	Rna-binding protein
FOC37_RS22575	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC37_RS22580	COG0745	RESPONSE REGULATOR receiver
FOC37_RS22585	COG0642	Histidine kinase
FOC37_RS22590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC37_RS22595	COG0697	spore germination
FOC37_RS22610	COG0142	geranyltranstransferase activity
FOC37_RS22625	COG3423	Transcriptional regulator