locus-tag	class	description
HRD69_RS00015	ENOG4105CQM	Urea amidohydrolase subunit alpha
HRD69_RS00025	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HRD69_RS00030	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS00040	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS00045	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS00050	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HRD69_RS00055	ENOG4105VEQ	Cold shock protein
HRD69_RS00065	ENOG4108SAJ	Protein of unknown function (DUF1198)
HRD69_RS00070	ENOG4108WMJ	Protein of unknown function (DUF2002)
HRD69_RS00080	ENOG4105TNS	Conserved Protein
HRD69_RS00090	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HRD69_RS00095	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
HRD69_RS00100	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HRD69_RS00105	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD69_RS00110	ENOG4107R25	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD69_RS00115	ENOG4108IJ7	Glycine betaine
HRD69_RS00125	ENOG4105GIJ	Glycine betaine
HRD69_RS00160	ENOG4105CKT	filamentous hemagglutinin
HRD69_RS00165	ENOG4105D5K	Hemolysin activator protein
HRD69_RS00175	ENOG4107RZZ	dna polymerase iii epsilon subunit
HRD69_RS00180	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRD69_RS00185	ENOG4105D1A	Methyltransferase
HRD69_RS00190	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HRD69_RS00195	ENOG4105E9H	Lytic Murein transglycosylase
HRD69_RS00200	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HRD69_RS00205	ENOG4105CV8	reductase
HRD69_RS00210	ENOG4105HEI	LysR family (Transcriptional regulator
HRD69_RS00215	ENOG4105F27	Major Facilitator
HRD69_RS00240	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HRD69_RS00250	ENOG4108UMI	ABC transporter, permease
HRD69_RS00255	ENOG4105D01	(LipO)protein
HRD69_RS00260	ENOG4108R8X	outer membrane lipoprotein
HRD69_RS00265	ENOG4108R96	Methyltransferase, YaeB family
HRD69_RS00275	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HRD69_RS00280	ENOG4108YZN	class I peptide chain release factor
HRD69_RS00285	ENOG4108VWS	Yaeq family
HRD69_RS00295	ENOG4105M1T	rho-binding antiterminator
HRD69_RS00310	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HRD69_RS00325	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HRD69_RS00330	ENOG4105C0B	DNA polymerase III (alpha subunit)
HRD69_RS00335	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRD69_RS00345	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD69_RS00355	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD69_RS00360	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HRD69_RS00370	ENOG4105DZP	Membrane-associated zinc metalloprotease
HRD69_RS00375	ENOG4105KNE	Phosphatidate cytidylyltransferase
HRD69_RS00385	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HRD69_RS00390	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HRD69_RS00395	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HRD69_RS00400	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HRD69_RS00405	ENOG4105CE9	30S ribosomal protein S2
HRD69_RS00410	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HRD69_RS00415	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HRD69_RS00420	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HRD69_RS00425	ENOG4108T8E	UPF0325 protein
HRD69_RS00435	ENOG4105QDK	Flavodoxin
HRD69_RS00440	ENOG4105DR9	pseudouridine synthase
HRD69_RS00445	ENOG4105WP7	tRNA pseudouridine synthase C
HRD69_RS00450	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HRD69_RS00455	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HRD69_RS00460	ENOG4105EWT	decarboxylase family
HRD69_RS00470	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HRD69_RS00475	ENOG4105M08	Membrane
HRD69_RS00480	ENOG4105ETT	transcriptional Regulator, LysR family
HRD69_RS00485	ENOG4105M5B	(LipO)protein
HRD69_RS00490	ENOG4105C9B	Cysteine desulfurase
HRD69_RS00495	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRD69_RS00500	ENOG4105CUZ	uba thif-type nad fad binding protein
HRD69_RS00505	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HRD69_RS00525	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRD69_RS00530	ENOG4107QZM	n-acetylglutamate synthase
HRD69_RS00535	ENOG4107QYX	exodeoxyribonuclease v alpha
HRD69_RS00540	ENOG4107QKA	exodeoxyribonuclease V beta
HRD69_RS00545	ENOG4107QXK	peptidase
HRD69_RS00550	ENOG4105DSY	exodeoxyribonuclease V, gamma
HRD69_RS00565	ENOG4105JCS	prepilin peptidase dependent protein
HRD69_RS00580	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HRD69_RS00585	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HRD69_RS00590	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HRD69_RS00600	ENOG4105EE5	Membrane protein terC
HRD69_RS00605	ENOG4105CPC	Aldo Keto reductase
HRD69_RS00610	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HRD69_RS00615	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD69_RS00625	ENOG41060NJ	transcriptional regulator
HRD69_RS00635	ENOG4105RQF	LysR family Transcriptional regulator
HRD69_RS00640	ENOG4105F27	Major Facilitator
HRD69_RS00645	ENOG4105EJC	lysr family transcriptional regulator
HRD69_RS00660	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS00685	ENOG4107B2H	carbonic anhydrase
HRD69_RS00690	ENOG4105KVH	Transcriptional regulator
HRD69_RS00695	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HRD69_RS00705	ENOG4105DVC	DnaJ domain protein
HRD69_RS00715	ENOG4105DPW	Major facilitator superfamily MFS_1
HRD69_RS00730	ENOG4105BZU	Histidine kinase
HRD69_RS00740	ENOG4105CRK	lysyL-tRNA synthetase
HRD69_RS00750	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HRD69_RS00755	ENOG4105T95	Thiol disulfide interChange protein
HRD69_RS00760	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD69_RS00765	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HRD69_RS00770	ENOG4105CT7	inner membrane cred family protein
HRD69_RS00775	ENOG4105EB3	Histidine kinase
HRD69_RS00780	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD69_RS00795	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HRD69_RS00800	ENOG4108UT2	hemolysin iii
HRD69_RS00805	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HRD69_RS00810	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HRD69_RS00815	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HRD69_RS00820	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HRD69_RS00825	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRD69_RS00830	ENOG4105D0A	hydroxylase
HRD69_RS00835	ENOG4107RAQ	aminopeptidase
HRD69_RS00840	ENOG4105E07	UPF0149 protein
HRD69_RS00845	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HRD69_RS00855	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HRD69_RS00860	ENOG4108JQ1	Dehydrogenase
HRD69_RS00865	ENOG4105E66	phosphoriboisomerase A
HRD69_RS00870	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HRD69_RS00875	ENOG4105MPN	Membrane
HRD69_RS00880	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HRD69_RS00885	ENOG4105D64	Mechanosensitive ion channel
HRD69_RS00890	ENOG4105D2N	Aldolase
HRD69_RS00895	ENOG4105BZA	Phosphoglycerate kinase
HRD69_RS00900	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HRD69_RS00905	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HRD69_RS00910	ENOG4108K0D	peptidase, M48
HRD69_RS00920	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HRD69_RS00925	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HRD69_RS00940	ENOG41080HT	Transcriptional regulator, arsr family
HRD69_RS00945	ENOG4105GPY	SprT protein
HRD69_RS00950	ENOG4105RWS	endonuclease I
HRD69_RS00955	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HRD69_RS00960	ENOG4105D7Z	glutathione synthase
HRD69_RS00965	ENOG4108UJU	UPF0301 protein
HRD69_RS00970	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HRD69_RS00975	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HRD69_RS00985	ENOG4105CZX	twitching motility protein
HRD69_RS00990	ENOG4105DFA	alanine racemase domain protein
HRD69_RS00995	ENOG4105II7	pyrroline-5-carboxylate reductase
HRD69_RS01000	ENOG4108VIA	integral membrane protein
HRD69_RS01005	ENOG4105VZ9	UPF0235 protein
HRD69_RS01010	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRD69_RS01015	ENOG4105CSA	Coproporphyrinogen iii oxidase
HRD69_RS01025	ENOG4105EUK	rtx toxin RtxA
HRD69_RS01030	ENOG4105K33	Periplasmic Protein
HRD69_RS01040	ENOG41090ED	Protein with unknown function (DUF469)
HRD69_RS01045	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HRD69_RS01050	ENOG4105CEN	a g-specific adenine glycosylase
HRD69_RS01060	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HRD69_RS01065	ENOG4105CXN	decarboxylase
HRD69_RS01135	ENOG4105EQR	Transposase IS116 IS110 IS902
HRD69_RS01230	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD69_RS01270	ENOG4108Q2J	Inner membrane protein YebE
HRD69_RS01335	ENOG4108MXD	gtp-binding protein
HRD69_RS01340	ENOG4106H6R	UPF0380 protein
HRD69_RS01350	ENOG4105MFG	Antirestriction protein
HRD69_RS01355	ENOG4105W5Q	DNA repair protein (RadC
HRD69_RS01370	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
HRD69_RS01380	ENOG4105CHM	Aminotransferase
HRD69_RS01390	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HRD69_RS01435	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS01450	ENOG4105CJZ	response regulator
HRD69_RS01460	ENOG4108Z33	Thiol disulfide Interchange Protein
HRD69_RS01470	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HRD69_RS01475	ENOG4108IPW	abc transporter atp-binding protein
HRD69_RS01480	ENOG4105CM4	permease protein
HRD69_RS01500	ENOG4105ETE	Transcriptional regulator (LacI family
HRD69_RS01510	ENOG4105EAM	Na Pi-cotransporter
HRD69_RS01525	ENOG4105CSH	Transporter
HRD69_RS01530	ENOG4107FQ9	ethanolamine ammonia-lyase
HRD69_RS01535	ENOG4105CPD	ethanolamine ammonia-lyase
HRD69_RS01540	ENOG4105C85	amino acid
HRD69_RS01565	ENOG4105C8H	hydrogenase maturation protein Hypf
HRD69_RS01570	ENOG4105C45	hydrogenase expression formation protein (HypE)
HRD69_RS01575	ENOG4105CQS	hydrogenase expression formation protein HypD
HRD69_RS01580	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
HRD69_RS01585	ENOG4107RSS	Hydrogenase accessory protein HypB
HRD69_RS01590	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HRD69_RS01595	ENOG4108WGS	hydrogenase 2-specific chaperone
HRD69_RS01600	ENOG4108USZ	hydrogenase
HRD69_RS01605	ENOG4105DPX	Hydrogenase, large subunit
HRD69_RS01610	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
HRD69_RS01615	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD69_RS01620	ENOG4105E3S	small subunit
HRD69_RS01635	ENOG4108XTF	Outer Membrane Lipoprotein
HRD69_RS01655	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS01660	ENOG4105CQ0	ABC transporter
HRD69_RS01665	ENOG4107RAN	Peptidase, M16
HRD69_RS01670	ENOG4105PE1	Receptor
HRD69_RS01680	ENOG4108SF5	RNA Polymerase
HRD69_RS01685	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
HRD69_RS01690	ENOG4105DQ5	transport system permease protein
HRD69_RS01695	ENOG4105TVJ	transport system, permease
HRD69_RS01700	ENOG4105E0A	ABC, transporter
HRD69_RS01725	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HRD69_RS01730	ENOG4108IJF	Heavy metal efflux pump, CzcA
HRD69_RS01800	ENOG4108ZZF	transport protein (ExbD)
HRD69_RS01805	ENOG4105CWK	Biopolymer transport protein, ExbB
HRD69_RS01810	ENOG4105C28	cystathionine
HRD69_RS01815	ENOG4108K81	inner membrane protein YghB
HRD69_RS01820	ENOG4105CF7	AraC family transcriptional regulator
HRD69_RS01825	ENOG4108I6A	alcohol dehydrogenase
HRD69_RS01830	ENOG4105CV8	reductase
HRD69_RS01840	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
HRD69_RS01845	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HRD69_RS01850	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD69_RS01855	ENOG4105NF4	modulator of drug activity
HRD69_RS01860	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HRD69_RS01865	ENOG4105JQN	Transcriptional regulator
HRD69_RS01870	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD69_RS01875	ENOG4105IPS	esterase
HRD69_RS01880	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HRD69_RS01885	ENOG4108SX3	cytoplasmic protein
HRD69_RS01890	ENOG41087AY	ADP-Ribose pyrophosphatase
HRD69_RS01895	ENOG4105DFG	type I secretion outer membrane protein
HRD69_RS01905	ENOG4106032	Glutathionylspermidine synthase
HRD69_RS01910	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HRD69_RS01915	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HRD69_RS01920	ENOG4105W0Z	cytoplasmic protein
HRD69_RS01925	ENOG4105DVH	amino acid
HRD69_RS01930	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HRD69_RS01935	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HRD69_RS01940	ENOG4105I7R	Adenylate cyclase
HRD69_RS01945	ENOG4106MWK	domain protein
HRD69_RS01950	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HRD69_RS01955	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HRD69_RS01960	ENOG4107ZVW	dihydroneopterin aldolase
HRD69_RS01965	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HRD69_RS01970	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRD69_RS01980	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HRD69_RS01985	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD69_RS01995	ENOG4108Z33	Thiol disulfide Interchange Protein
HRD69_RS02000	ENOG4107U2T	alpha beta
HRD69_RS02005	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HRD69_RS02010	ENOG4105VS8	Flagellar biosynthetic protein fliq
HRD69_RS02015	ENOG4105CN7	Flagellar biosynthetic protein FliP
HRD69_RS02020	ENOG4105K0P	flagellar biosynthesis protein
HRD69_RS02025	ENOG4105DD5	Flagellar motor switch protein
HRD69_RS02030	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD69_RS02035	ENOG4107ZI8	flagellar basal body-associated protein flil
HRD69_RS02040	ENOG4105WF4	Flagellar hook-length control protein
HRD69_RS02050	ENOG4108JIR	Flagellum-specific ATP synthase
HRD69_RS02060	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD69_RS02065	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HRD69_RS02070	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HRD69_RS02075	ENOG4105BZU	Histidine kinase
HRD69_RS02080	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HRD69_RS02085	ENOG4108VYJ	response regulator receiver protein
HRD69_RS02090	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HRD69_RS02095	ENOG4105D00	flagellar biosynthetic protein flhB
HRD69_RS02100	ENOG4105D7B	Flagellar biosynthesis protein flha
HRD69_RS02105	ENOG4105W13	flagellar protein
HRD69_RS02115	ENOG4105MQ3	flagellar protein FliS
HRD69_RS02120	ENOG4105DTS	flagellar hook-associated
HRD69_RS02125	ENOG4105I03	Flagellin
HRD69_RS02135	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS02140	ENOG4108V3W	Chemotaxis protein, CheW
HRD69_RS02145	ENOG4105CBS	Chea signal transduction histidine kinase
HRD69_RS02150	ENOG4105ER2	Ompa motb domain protein
HRD69_RS02155	ENOG4107RD7	Flagellar Motor Protein, MotA
HRD69_RS02160	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HRD69_RS02165	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HRD69_RS02170	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD69_RS02175	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS02180	ENOG4105DTJ	flagellar hook-associated protein
HRD69_RS02185	ENOG4105E1Q	flagellar hook-associated protein
HRD69_RS02190	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HRD69_RS02195	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HRD69_RS02205	ENOG4105CGA	flagellar basal-body rod protein FlgG
HRD69_RS02210	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HRD69_RS02215	ENOG4105BZE	flagellar hook protein, FlgE
HRD69_RS02220	ENOG4105W00	Flagellar hook capping protein
HRD69_RS02225	ENOG4108ZC9	flagellar basal-body rod protein flgc
HRD69_RS02230	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HRD69_RS02235	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HRD69_RS02250	ENOG4108YK4	Acid-resistance membrane protein
HRD69_RS02255	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRD69_RS02290	ENOG4105DUM	transcriptional regulator, lysR family
HRD69_RS02300	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HRD69_RS02310	ENOG4108VKG	metal-dependent hydrolase
HRD69_RS02315	ENOG4105EE0	oxidoreductase
HRD69_RS02320	ENOG4105DU1	integral membrane protein, terc
HRD69_RS02325	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HRD69_RS02330	ENOG4105P66	Membrane
HRD69_RS02335	ENOG4105CTX	dehydratase
HRD69_RS02345	ENOG4105D2H	Uronic isomerase
HRD69_RS02350	ENOG4105DPW	Major facilitator superfamily MFS_1
HRD69_RS02365	ENOG4106W5V	Membrane
HRD69_RS02380	ENOG4105NE1	Conserved Protein
HRD69_RS02385	ENOG41090KG	Inner membrane protein YqjE
HRD69_RS02390	ENOG4105YJD	
HRD69_RS02395	ENOG4108VBZ	doxx family
HRD69_RS02400	ENOG4105CWB	LysR family transcriptional Regulator
HRD69_RS02405	ENOG4108CNN	domain protein
HRD69_RS02410	ENOG4105DQ4	alcohol dehydrogenase
HRD69_RS02440	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HRD69_RS02450	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS02455	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
HRD69_RS02465	ENOG41065KQ	synthase
HRD69_RS02500	ENOG4108RQP	Major type 1 subunit fimbrin
HRD69_RS02505	ENOG4105CW0	outer membrane usher protein
HRD69_RS02510	ENOG4108AF8	Chaperone
HRD69_RS02515	ENOG4108S54	Fimbrial protein
HRD69_RS02520	ENOG4108WDE	Fimbrial protein
HRD69_RS02525	ENOG4105CMB	EAL domain-containing protein
HRD69_RS02540	ENOG4108S1B	Periplasmic chaperone protein
HRD69_RS02545	ENOG4105E6S	usher protein(
HRD69_RS02565	ENOG4108WQH	regulatoR
HRD69_RS02570	ENOG4105BZU	Histidine kinase
HRD69_RS02580	ENOG4106PYX	Receptor
HRD69_RS02585	ENOG4108N3D	putative enzyme
HRD69_RS02595	ENOG4108GWT	fimbrillin MatB
HRD69_RS02605	ENOG4108MBX	Secretion Protein
HRD69_RS02610	ENOG4108JJA	ABC, transporter
HRD69_RS02710	ENOG4107YC3	synthase
HRD69_RS02745	ENOG4107QHF	type ii secretion system protein e
HRD69_RS02790	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HRD69_RS02800	ENOG41082RQ	UPF0102 protein
HRD69_RS02805	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HRD69_RS02810	ENOG4105W4M	Transport-associated protein
HRD69_RS02815	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HRD69_RS02820	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HRD69_RS02825	ENOG4105BZU	Histidine kinase
HRD69_RS02830	ENOG4105N5T	Radical SAM Protein
HRD69_RS02835	ENOG4105CBC	glutamate synthase
HRD69_RS02840	ENOG4105BZ8	glutamate synthase
HRD69_RS02850	ENOG4105KB2	stringent starvation protein b
HRD69_RS02855	ENOG4107MKT	Stringent starvation protein a
HRD69_RS02860	ENOG4108UJD	30S ribosomal protein S9
HRD69_RS02865	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HRD69_RS02870	ENOG4105D6Z	AFG1 family ATPase
HRD69_RS02875	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HRD69_RS02880	ENOG4105C0H	protease
HRD69_RS02885	ENOG4105C0H	protease
HRD69_RS02895	ENOG4105VFK	BolA family
HRD69_RS02900	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
HRD69_RS02905	ENOG4105E3I	toluene tolerance
HRD69_RS02910	ENOG4107PE3	Mammalian cell entry related domain protein
HRD69_RS02915	ENOG4105CY3	ABC transporter, permease
HRD69_RS02920	ENOG4105DHJ	ABC, transporter
HRD69_RS02925	ENOG4105FEU	K -dependent Na -Ca exchanger
HRD69_RS02930	ENOG4105C2X	Arabinose 5-phosphate isomerase
HRD69_RS02935	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HRD69_RS02940	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HRD69_RS02945	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HRD69_RS02950	ENOG4108IUZ	ABC transporter
HRD69_RS02955	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD69_RS02960	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HRD69_RS02965	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HRD69_RS02970	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HRD69_RS02975	ENOG41080Z8	PHOSPHOCARRIER protein
HRD69_RS02980	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HRD69_RS02985	ENOG4108N2Y	auxin Efflux
HRD69_RS02990	ENOG4105CXT	aspartate transcarbamylase
HRD69_RS02995	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HRD69_RS03000	ENOG4105KME	endoribonuclease L-psp
HRD69_RS03040	ENOG4105D4X	repressor
HRD69_RS03045	ENOG4105C5Y	PTS System
HRD69_RS03050	ENOG4105CG3	alpha amylase, catalytic region
HRD69_RS03055	ENOG4105EMD	TRANSCRIPTIONal
HRD69_RS03070	ENOG41069H0	dihydroorotase EC 3.5.2.3
HRD69_RS03100	ENOG4105NXH	GreA GreB family elongation factor
HRD69_RS03105	ENOG4108XVM	Cytochrome b(562)
HRD69_RS03115	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HRD69_RS03120	ENOG4105N42	UPF0307 protein
HRD69_RS03125	ENOG4105UNR	(Barnase) inhibitor
HRD69_RS03135	ENOG4105C26	Dehydrogenase
HRD69_RS03140	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
HRD69_RS03145	ENOG4105Y49	secretion protein, HlyD family
HRD69_RS03155	ENOG4105CR8	Transcriptional regulator
HRD69_RS03200	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HRD69_RS03210	ENOG4105QD6	exported protein
HRD69_RS03215	ENOG4105C03	ribonuclease
HRD69_RS03220	ENOG4108Z03	MAF-like protein
HRD69_RS03225	ENOG4105VQ7	Rod shape-determining protein MreD
HRD69_RS03230	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HRD69_RS03240	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HRD69_RS03245	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HRD69_RS03255	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HRD69_RS03260	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HRD69_RS03265	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HRD69_RS03270	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HRD69_RS03275	ENOG4105RG0	Membrane
HRD69_RS03280	ENOG4108IA2	Sodium pantothenate symporter
HRD69_RS03285	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HRD69_RS03290	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRD69_RS03295	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HRD69_RS03305	ENOG4108XTF	Outer Membrane Lipoprotein
HRD69_RS03310	ENOG4105VEQ	Cold shock protein
HRD69_RS03315	ENOG4105VEQ	Cold shock protein
HRD69_RS03320	ENOG4107QPK	)-transporter
HRD69_RS03325	ENOG4105C2X	Arabinose 5-phosphate isomerase
HRD69_RS03330	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HRD69_RS03340	ENOG4105CNN	ABC, transporter
HRD69_RS03345	ENOG4105C2J	ABC transporter
HRD69_RS03355	ENOG4105D1S	lipid A biosynthesis
HRD69_RS03365	ENOG4105EZ7	amino acid ABC transporter
HRD69_RS03370	ENOG4105DRP	amino acid AbC transporter
HRD69_RS03375	ENOG4105CDA	abc transporter atp-binding protein
HRD69_RS03400	ENOG4105CMU	LysR family (Transcriptional regulator
HRD69_RS03405	ENOG4105EEQ	Na H antiporter
HRD69_RS03410	ENOG4105C7N	Xanthine uracil vitamin C permease
HRD69_RS03420	ENOG4108UUM	single-stranded DNA-binding protein
HRD69_RS03425	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HRD69_RS03430	ENOG4105MSB	protein, conserved in bacteria
HRD69_RS03435	ENOG4105CGF	Aromatic amino acid aminotransferase
HRD69_RS03445	ENOG4105CDU	Replicative dna helicase
HRD69_RS03450	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HRD69_RS03460	ENOG4105P4Z	Phage shock protein G
HRD69_RS03465	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRD69_RS03470	ENOG4105MYN	Zinc uptake regulation protein
HRD69_RS03475	ENOG4105VDW	Csbd family
HRD69_RS03480	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HRD69_RS03485	ENOG41080IJ	Diacylglycerol kinase
HRD69_RS03490	ENOG4105E55	glycerol-3-phosphate acyltransferase
HRD69_RS03500	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HRD69_RS03505	ENOG4107W52	maltose operon periplasmic protein
HRD69_RS03520	ENOG4107FKK	extracellular solute-binding protein family 1
HRD69_RS03525	ENOG4105D56	permease protein
HRD69_RS03530	ENOG4105EG2	ABC transporter, permease
HRD69_RS03535	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HRD69_RS03545	ENOG4105CFH	Aspartokinase
HRD69_RS03550	ENOG4105C3R	Methionine synthase
HRD69_RS03555	ENOG41069M3	Transcriptional regulator
HRD69_RS03560	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HRD69_RS03565	ENOG4108I9X	Isocitrate lyase
HRD69_RS03570	ENOG4107QP3	malate synthase g
HRD69_RS03575	ENOG4105CVG	Homoserine O-transsuccinylase
HRD69_RS03620	ENOG4105C12	Phosphoribosylglycinamide synthetase
HRD69_RS03625	ENOG4108T8B	Protein of unknown function (DUF1481)
HRD69_RS03635	ENOG4105R2J	Conserved Protein
HRD69_RS03640	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HRD69_RS03645	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HRD69_RS03650	ENOG4105E09	nadh pyrophosphatase
HRD69_RS03655	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
HRD69_RS03670	ENOG4105D06	uba thif-type nad fad binding protein
HRD69_RS03675	ENOG4105WHD	thiamine biosynthesis protein ThiS
HRD69_RS03680	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HRD69_RS03685	ENOG4105D41	biosynthesis protein thiH
HRD69_RS03690	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
HRD69_RS03700	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD69_RS03705	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD69_RS03710	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HRD69_RS03715	ENOG4108VZM	50s ribosomal protein L10
HRD69_RS03720	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HRD69_RS03725	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HRD69_RS03730	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HRD69_RS03735	ENOG4105PM1	preprotein translocase subunit SecE
HRD69_RS03740	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRD69_RS03775	ENOG4105CS9	pantothenic acid kinase
HRD69_RS03780	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HRD69_RS03810	ENOG4108RR8	protoporphyrinogen oxidase
HRD69_RS03815	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HRD69_RS03820	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HRD69_RS03830	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HRD69_RS03835	ENOG4105CHU	acetyl-coa acetyltransferase
HRD69_RS03840	ENOG4107QK7	reductase
HRD69_RS03845	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HRD69_RS03850	ENOG4105MDZ	Transcriptional activator rfaH
HRD69_RS03855	ENOG4105D52	delta-aminolevulinic acid dehydratase
HRD69_RS03865	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HRD69_RS03870	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HRD69_RS03875	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HRD69_RS03880	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HRD69_RS03885	ENOG4105JC1	sterol-binding domain protein
HRD69_RS03890	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HRD69_RS03895	ENOG4105CGY	Dna recombination protein
HRD69_RS03900	ENOG4108KF1	Membrane
HRD69_RS03915	ENOG4107SXA	Phosphorylase
HRD69_RS03920	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HRD69_RS03925	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HRD69_RS03930	ENOG4105DZ2	Transcriptional regulator
HRD69_RS03935	ENOG4105EMK	carboxylate amino acid amine transporter
HRD69_RS03940	ENOG4105RK9	auxin efflux carrier
HRD69_RS03945	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HRD69_RS03950	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS03955	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS03960	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HRD69_RS03965	ENOG4105BZ7	extracellular solute-binding protein family 1
HRD69_RS04015	ENOG4108IV0	ABC, transporter
HRD69_RS04020	ENOG4105C0Z	ABC transporter
HRD69_RS04025	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HRD69_RS04030	ENOG4105C32	Amino acid ABC transporter (Permease)
HRD69_RS04035	ENOG4105CP9	extracellular ligand-binding receptor
HRD69_RS04040	ENOG4105U59	-acetyltransferase
HRD69_RS04050	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HRD69_RS04055	ENOG4105CAK	Cell division ATP-binding protein ftsE
HRD69_RS04060	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HRD69_RS04060	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HRD69_RS04065	ENOG4106H78	methyltransferase
HRD69_RS04070	ENOG4105MG3	Membrane
HRD69_RS04085	ENOG4107FS9	Membrane
HRD69_RS04100	ENOG4105EX9	Membrane
HRD69_RS04105	ENOG4108W1V	Lipoprotein
HRD69_RS04110	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HRD69_RS04120	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HRD69_RS04125	ENOG4105CXY	transporter
HRD69_RS04130	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HRD69_RS04135	ENOG4105DQF	Hydrolase
HRD69_RS04140	ENOG4108EUD	Lysophospholipase
HRD69_RS04145	ENOG410829K	Lysine exporter protein (Lyse ygga)
HRD69_RS04150	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HRD69_RS04155	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HRD69_RS04160	ENOG4105HDD	phospholipase
HRD69_RS04165	ENOG4108VUY	thioesterase Superfamily protein
HRD69_RS04170	ENOG4105FR1	rard protein
HRD69_RS04190	ENOG4105EQN	UPF0261 protein
HRD69_RS04200	ENOG4105C4R	Atp-dependent dna helicase
HRD69_RS04205	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HRD69_RS04210	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRD69_RS04215	ENOG4105CT0	Protein of unknown function, DUF484
HRD69_RS04220	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HRD69_RS04225	ENOG4105S7Z	(LipO)protein
HRD69_RS04230	ENOG4105XQ6	frataxin-like protein
HRD69_RS04240	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HRD69_RS04245	ENOG41076E6	Uroporphyrinogen-III Synthase
HRD69_RS04250	ENOG4105ECF	c-methyltransferase
HRD69_RS04255	ENOG410601J	HemY protein
HRD69_RS04280	ENOG4105C85	amino acid
HRD69_RS04295	ENOG4105F18	Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis (By similarity)
HRD69_RS04300	ENOG4105EGZ	biosynthesis protein
HRD69_RS04305	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD69_RS04310	ENOG4108WJ1	acetyltransferase
HRD69_RS04315	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HRD69_RS04320	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HRD69_RS04325	ENOG4108IJ1	Dehydrogenase
HRD69_RS04330	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HRD69_RS04335	ENOG4105SFE	lipopolysaccharide biosynthesis protein
HRD69_RS04340	ENOG4105ESV	Glycosyl transferase, family 4
HRD69_RS04345	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HRD69_RS04360	ENOG4105C9X	ppx gppa phosphatase
HRD69_RS04395	ENOG4105C4R	Atp-dependent dna helicase
HRD69_RS04400	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HRD69_RS04410	ENOG4108MQF	Chaperone
HRD69_RS04415	ENOG4105CW0	outer membrane usher protein
HRD69_RS04425	ENOG4108VEV	chaperone
HRD69_RS04430	ENOG4108N67	choline binding protein
HRD69_RS04470	ENOG4108MA7	Inherit from COG: YD repeat protein
HRD69_RS04480	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HRD69_RS04485	ENOG4105EMY	transcriptional regulator
HRD69_RS04495	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
HRD69_RS04500	ENOG41087RY	SpoVT_AbrB
HRD69_RS04530	ENOG4105C7B	Threonine dehydratase
HRD69_RS04535	ENOG4105C01	Dihydroxy-acid dehydratase
HRD69_RS04540	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HRD69_RS04545	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HRD69_RS04560	ENOG4105C0P	Mg chelatase subunit ChlI
HRD69_RS04565	ENOG4108WFC	UPF0438 protein yifE
HRD69_RS04570	ENOG4105CVI	Transcriptional regulator
HRD69_RS04575	ENOG41062B0	ABC transporter, permease
HRD69_RS04580	ENOG4107R9N	ABC transporter
HRD69_RS04585	ENOG4105C2J	ABC transporter
HRD69_RS04590	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
HRD69_RS04630	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HRD69_RS04640	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HRD69_RS04645	ENOG4108Y73	Membrane
HRD69_RS04655	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HRD69_RS04665	ENOG4105EHV	domain protein
HRD69_RS04670	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRD69_RS04690	ENOG4107QZV	Type I secretion membrane fusion protein
HRD69_RS04730	ENOG4105CH7	arginosuccinase
HRD69_RS04755	ENOG4105DP0	ferredoxin-NADP reductase
HRD69_RS04760	ENOG4105E5M	Multidrug resistance protein D
HRD69_RS04765	ENOG4105CBT	Fructose-1,6-bisphosphatase
HRD69_RS04770	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HRD69_RS04775	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD69_RS04780	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HRD69_RS04785	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HRD69_RS04790	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HRD69_RS04795	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HRD69_RS04800	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HRD69_RS04805	ENOG41063M6	Cell Division Protein
HRD69_RS04810	ENOG4105ETE	Transcriptional regulator (LacI family
HRD69_RS04815	ENOG4105C25	Primosomal protein n'
HRD69_RS04820	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HRD69_RS04825	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HRD69_RS04830	ENOG4105C28	cystathionine
HRD69_RS04835	ENOG4105CFH	Aspartokinase
HRD69_RS04845	ENOG4105SYT	Methylenetetrahydrofolate reductase
HRD69_RS04850	ENOG4108VTS	Membrane
HRD69_RS04855	ENOG4105EBK	exported protein
HRD69_RS04865	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HRD69_RS04875	ENOG41076HS	cation diffusion facilitator family transporter
HRD69_RS04880	ENOG4105FMW	periplasmic
HRD69_RS04885	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD69_RS04890	ENOG4105E0F	Histidine kinase
HRD69_RS04895	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HRD69_RS04900	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HRD69_RS04905	ENOG4105D7W	serine acetyltransferase
HRD69_RS04910	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HRD69_RS04915	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HRD69_RS04920	ENOG4105VW4	glutaredoxin 3
HRD69_RS04925	ENOG4107YZP	Rhodanese domain protein
HRD69_RS04930	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRD69_RS04935	ENOG41063SB	peptidase
HRD69_RS04940	ENOG4105PXI	polysaccharide deacetylase
HRD69_RS04950	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRD69_RS04955	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HRD69_RS04960	ENOG4105XA0	heptosyltransferase ii
HRD69_RS04965	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HRD69_RS04970	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HRD69_RS04990	ENOG4105W0E	50S ribosomal protein L33
HRD69_RS04995	ENOG4105KDC	50s ribosomal protein l28
HRD69_RS05005	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HRD69_RS05010	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HRD69_RS05015	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HRD69_RS05025	ENOG4108PU9	oligogalacturonate-specific porin
HRD69_RS05030	ENOG4105BZU	Histidine kinase
HRD69_RS05035	ENOG4108JQ7	(ABC) transporter
HRD69_RS05040	ENOG4105C3U	ABC transporter
HRD69_RS05045	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS05050	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS05055	ENOG4105DEF	Extracellular solute-binding protein, family 5
HRD69_RS05065	ENOG4105D5K	Hemolysin activator protein
HRD69_RS05075	ENOG4105CXY	transporter
HRD69_RS05080	ENOG4105BZU	Histidine kinase
HRD69_RS05085	ENOG4108KX4	response regulator
HRD69_RS05090	ENOG4105DIJ	Phosphoethanolamine transferase
HRD69_RS05095	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HRD69_RS05105	ENOG4105C85	amino acid
HRD69_RS05110	ENOG4105C84	Histidine ammonia-lyase
HRD69_RS05115	ENOG4105CGP	Urocanate hydratase
HRD69_RS05120	ENOG4105BZU	Histidine kinase
HRD69_RS05125	ENOG4105E39	Enoyl-CoA hydratase
HRD69_RS05130	ENOG4105D9N	nucleoside
HRD69_RS05140	ENOG4105EN6	Membrane
HRD69_RS05145	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
HRD69_RS05160	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRD69_RS05165	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HRD69_RS05170	ENOG4105CB5	ATP-dependent DNA helicase recG
HRD69_RS05175	ENOG4105D6U	Sodium Glutamate Symporter
HRD69_RS05180	ENOG4105C2W	permease
HRD69_RS05185	ENOG4105JV1	AsmA family
HRD69_RS05210	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS05225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD69_RS05230	ENOG4105SUU	thioesterase domain
HRD69_RS05235	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HRD69_RS05240	ENOG4107S2Z	UPF0761 membrane protein
HRD69_RS05245	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
HRD69_RS05250	ENOG4105CI3	gtp-binding protein typa
HRD69_RS05255	ENOG4105C5F	glutamine synthetase
HRD69_RS05260	ENOG4105CUX	Signal transduction histidine kinase
HRD69_RS05265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD69_RS05270	ENOG4105D4P	Coproporphyrinogen iii oxidase
HRD69_RS05275	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HRD69_RS05285	ENOG4105C2M	dna polymerase I
HRD69_RS05290	ENOG4108Z33	Thiol disulfide Interchange Protein
HRD69_RS05295	ENOG4105E27	serine threonine protein kinase
HRD69_RS05300	ENOG4105PC1	Conserved Protein
HRD69_RS05310	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HRD69_RS05335	ENOG4107EJG	GntR family transcriptional regulator
HRD69_RS05340	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD69_RS05345	ENOG4105ETE	Transcriptional regulator (LacI family
HRD69_RS05350	ENOG4108RVA	ribokinase
HRD69_RS05355	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HRD69_RS05360	ENOG4105CNN	ABC, transporter
HRD69_RS05365	ENOG4105C2J	ABC transporter
HRD69_RS05370	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HRD69_RS05380	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
HRD69_RS05385	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HRD69_RS05395	ENOG4105CU9	asparagine synthetase A
HRD69_RS05400	ENOG4108VVK	transcriptional Regulator, AsnC
HRD69_RS05405	ENOG4105QTB	Flavodoxin
HRD69_RS05410	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HRD69_RS05415	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HRD69_RS05420	ENOG4105GXX	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation
HRD69_RS05425	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HRD69_RS05430	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD69_RS05435	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD69_RS05440	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRD69_RS05445	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HRD69_RS05455	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HRD69_RS05460	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HRD69_RS05465	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HRD69_RS05485	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HRD69_RS05490	ENOG4105C8U	phosphate abc transporter
HRD69_RS05495	ENOG4105E2Z	phosphate ABC transporter (Permease
HRD69_RS05510	ENOG4106PMH	Extracellular solute-binding protein family 3
HRD69_RS05515	ENOG4105EAD	ABC transporter
HRD69_RS05520	ENOG4105DRP	amino acid AbC transporter
HRD69_RS05525	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HRD69_RS05530	ENOG4105C7N	Xanthine uracil vitamin C permease
HRD69_RS05550	ENOG4108YYH	Nadph-dependent fmn reductase
HRD69_RS05555	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS05560	ENOG4108UMI	ABC transporter, permease
HRD69_RS05565	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS05575	ENOG4105RKW	reductase (By
HRD69_RS05580	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HRD69_RS05585	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HRD69_RS05595	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HRD69_RS05605	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HRD69_RS05610	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HRD69_RS05620	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD69_RS05625	ENOG410667J	hydrolase
HRD69_RS05635	ENOG4105C7B	Threonine dehydratase
HRD69_RS05640	ENOG4108SGR	YheO domain-containing protein
HRD69_RS05645	ENOG4105D99	atp gtp-binding protein
HRD69_RS05650	ENOG4105R2A	(LipO)protein
HRD69_RS05665	ENOG4105D0C	transport protein
HRD69_RS05675	ENOG4105EMU	Dehydrogenase
HRD69_RS05680	ENOG4105F27	Major Facilitator
HRD69_RS05685	ENOG4105DIN	metallophosphoesterase
HRD69_RS05690	ENOG410642W	LysR family Transcriptional regulator
HRD69_RS05700	ENOG4105EQ2	LysR family Transcriptional regulator
HRD69_RS05705	ENOG4107SET	aldo keto reductase
HRD69_RS05710	ENOG4105C2C	drug resistance transporter, Bcr CflA
HRD69_RS05715	ENOG4105JKW	Valine--pyruvate aminotransferase
HRD69_RS05720	ENOG4107T9C	Alpha amylase catalytic region
HRD69_RS05740	ENOG4108ZG0	Ompa motb domain protein
HRD69_RS05755	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HRD69_RS05765	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HRD69_RS05770	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HRD69_RS05775	ENOG4106JH6	(LipO)protein
HRD69_RS05785	ENOG4105CTS	PTS system mannitol-specific
HRD69_RS05790	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HRD69_RS05795	ENOG4105E61	Mannitol repressor protein
HRD69_RS05805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD69_RS05810	ENOG4108YYI	Protein of unknown function (DUF2810)
HRD69_RS05820	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HRD69_RS05825	ENOG4108RPX	mosc domain containing protein
HRD69_RS05830	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS05835	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRD69_RS05840	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HRD69_RS05850	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD69_RS05855	ENOG4108MG3	formate dehydrogenase
HRD69_RS05860	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HRD69_RS05865	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HRD69_RS05870	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HRD69_RS05875	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HRD69_RS05880	ENOG4105FB2	class II Aldolase
HRD69_RS05885	ENOG4105G63	Type III effector Hrp-dependent
HRD69_RS05890	ENOG4105MVE	transcriptional regulator
HRD69_RS05895	ENOG4105CSP	Major Facilitator Superfamily
HRD69_RS05900	ENOG4105EXW	epimerase dehydratase
HRD69_RS05915	ENOG4105MEV	Acyl-transferase
HRD69_RS05925	ENOG4108RWI	nicotinamidase
HRD69_RS05930	ENOG4105CMG	Carbohydrate kinase
HRD69_RS05935	ENOG4105C93	Xylose Isomerase
HRD69_RS05940	ENOG4105DFW	ABC transporter
HRD69_RS05950	ENOG4108HWW	ABC transporter
HRD69_RS05955	ENOG4105T16	Transcriptional regulator (AraC family)
HRD69_RS05965	ENOG4105DFP	Integrase
HRD69_RS05980	ENOG4105ZTC	transcriptional activator, Ogr delta
HRD69_RS06025	ENOG4108JQC	penicillin-binding protein 1A
HRD69_RS06035	ENOG4108WRK	Transcriptional regulator
HRD69_RS06040	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS06050	ENOG4105F5P	DNA-damage-inducible protein d
HRD69_RS06070	ENOG4105ZTC	transcriptional activator, Ogr delta
HRD69_RS06130	ENOG4105DSJ	YicC domain protein
HRD69_RS06135	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HRD69_RS06145	ENOG4105CK2	sodium dicarboxylate symporter
HRD69_RS06150	ENOG4105CS0	peptidase
HRD69_RS06155	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HRD69_RS06160	ENOG4105VSH	4-oxalocrotonate tautomerase
HRD69_RS06165	ENOG4105CMB	EAL domain-containing protein
HRD69_RS06170	ENOG41066T0	asmA family
HRD69_RS06175	ENOG4105EAF	CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26)
HRD69_RS06180	ENOG4107H3J	ribonuclease
HRD69_RS06190	ENOG4105DC8	reductase
HRD69_RS06195	ENOG4105D6S	protein involved in catabolism of external DNA
HRD69_RS06200	ENOG4105DGW	oligopeptidase A
HRD69_RS06205	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HRD69_RS06220	ENOG4108M6U	Universal stress protein A
HRD69_RS06225	ENOG4108V6B	universal stress protein B
HRD69_RS06230	ENOG4105CJ3	phosphate transporter
HRD69_RS06235	ENOG4105CBX	hi0933 family
HRD69_RS06260	ENOG4108AF8	Chaperone
HRD69_RS06265	ENOG4105CW0	outer membrane usher protein
HRD69_RS06280	ENOG4105CR8	Transcriptional regulator
HRD69_RS06300	ENOG4105C26	Dehydrogenase
HRD69_RS06305	ENOG4105DH8	myo-inositol catabolism
HRD69_RS06315	ENOG4105EDK	PfkB domain protein
HRD69_RS06320	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
HRD69_RS06325	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HRD69_RS06330	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
HRD69_RS06335	ENOG4105WCN	acetyltransferase
HRD69_RS06340	ENOG4105C2I	pirin domain protein
HRD69_RS06345	ENOG4105DIQ	Transcriptional regulator
HRD69_RS06350	ENOG4105C6Z	Gluconate
HRD69_RS06355	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HRD69_RS06360	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HRD69_RS06365	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRD69_RS06380	ENOG4107R0E	Glycosyl transferase, family 2
HRD69_RS06390	ENOG4108MBX	Secretion Protein
HRD69_RS06395	ENOG4108JJA	ABC, transporter
HRD69_RS06400	ENOG4108HRK	Histidine kinase
HRD69_RS06405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HRD69_RS06410	ENOG4108IUM	Glycogen debranching enzyme
HRD69_RS06420	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HRD69_RS06425	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HRD69_RS06430	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HRD69_RS06440	ENOG4105E98	transcriptional regulator DeoR family
HRD69_RS06445	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HRD69_RS06460	ENOG41061ZR	Transcriptional regulator
HRD69_RS06465	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HRD69_RS06470	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HRD69_RS06475	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HRD69_RS06480	ENOG4105MJ2	Competence protein
HRD69_RS06485	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HRD69_RS06490	ENOG4105RID	UPF0379 protein yhcN
HRD69_RS06495	ENOG41060N5	May function as a transcriptional regulator that controls feoABC expression (By similarity)
HRD69_RS06500	ENOG4105CE1	Ferrous iron transport protein b
HRD69_RS06505	ENOG4105XFK	Ferrous iron transport protein A
HRD69_RS06510	ENOG4105BZM	domain protein
HRD69_RS06515	ENOG4108RRZ	Transcription elongation factor GreB
HRD69_RS06525	ENOG4105E0F	Histidine kinase
HRD69_RS06535	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HRD69_RS06545	ENOG4105VEJ	Heat shock protein
HRD69_RS06550	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HRD69_RS06555	ENOG4105DQY	intracellular growth attenuator
HRD69_RS06560	ENOG4107RK2	ADP-ribose diphosphatase NudE
HRD69_RS06565	ENOG4108JQC	penicillin-binding protein 1A
HRD69_RS06590	ENOG4105E4G	Type IV pilus
HRD69_RS06595	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRD69_RS06615	ENOG4105DJV	ribulose-phosphate 3-epimerase
HRD69_RS06625	ENOG4105C31	Tryptophanyl-tRNA synthetase
HRD69_RS06630	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD69_RS06635	ENOG4107V9H	nitrite transporter
HRD69_RS06640	ENOG4105WZK	nitrite reductase NADPH small subunit
HRD69_RS06645	ENOG4107QZF	nitrite reductase NADPH large subunit
HRD69_RS06650	ENOG4105DZC	cytosine deaminase
HRD69_RS06655	ENOG4106DTQ	Protein TsgA homolog
HRD69_RS06670	ENOG41060NJ	transcriptional regulator
HRD69_RS06675	ENOG4105F8D	glycoside hydrolase family 4
HRD69_RS06680	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HRD69_RS06685	ENOG4105D7A	ATP-binding protein
HRD69_RS06695	ENOG4105C8Y	Acetylornithine aminotransferase
HRD69_RS06700	ENOG410613R	integral membrane protein, YccS YhfK family
HRD69_RS06705	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HRD69_RS06710	ENOG4108UKZ	OsmC family
HRD69_RS06715	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HRD69_RS06720	ENOG4105YP7	UPF0270 protein
HRD69_RS06725	ENOG4105DNZ	Alpha Beta Hydrolase
HRD69_RS06735	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HRD69_RS06740	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HRD69_RS06750	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS06755	ENOG4105E2B	Taurine dioxygenase
HRD69_RS06765	ENOG4105C5H	ABC transporter
HRD69_RS06770	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HRD69_RS06780	ENOG4105VKU	nucleicacid-binding protein
HRD69_RS06785	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HRD69_RS06795	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRD69_RS06800	ENOG4105WWK	YheO domain protein
HRD69_RS06805	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HRD69_RS06810	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HRD69_RS06815	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HRD69_RS06825	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HRD69_RS06835	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRD69_RS06855	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HRD69_RS06865	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HRD69_RS06870	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HRD69_RS06875	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HRD69_RS06880	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HRD69_RS06885	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HRD69_RS06890	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HRD69_RS06895	ENOG41083MP	50s ribosomal protein l29
HRD69_RS06900	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HRD69_RS06920	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HRD69_RS06930	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HRD69_RS06935	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HRD69_RS06940	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HRD69_RS06945	ENOG4105VPB	50S ribosomal protein L30
HRD69_RS06950	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HRD69_RS06955	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HRD69_RS06965	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HRD69_RS06970	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HRD69_RS06975	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HRD69_RS06980	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRD69_RS06985	ENOG4108ZT0	50S ribosomal protein l17
HRD69_RS06990	ENOG4105W1Y	Transcriptional regulator
HRD69_RS06995	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HRD69_RS07000	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HRD69_RS07005	ENOG4105C1A	potassium transporter peripheral membrane
HRD69_RS07010	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HRD69_RS07015	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HRD69_RS07020	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HRD69_RS07025	ENOG4105C79	DNA protecting protein DprA
HRD69_RS07035	ENOG4108WI1	Dna topoisomerase
HRD69_RS07040	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRD69_RS07045	ENOG4105E2X	shikimate dehydrogenase
HRD69_RS07050	ENOG4108Z0R	Transferase
HRD69_RS07080	ENOG4107QN1	sodium solute
HRD69_RS07085	ENOG41062QD	Membrane
HRD69_RS07090	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HRD69_RS07095	ENOG4105CK2	sodium dicarboxylate symporter
HRD69_RS07105	ENOG4105BZU	Histidine kinase
HRD69_RS07115	ENOG41066VF	YeeE YedE family protein
HRD69_RS07140	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD69_RS07145	ENOG4108S3W	Anti-feci sigma factor, fecr
HRD69_RS07150	ENOG4105PE1	Receptor
HRD69_RS07155	ENOG4105CQ0	ABC transporter
HRD69_RS07160	ENOG4105CS0	peptidase
HRD69_RS07165	ENOG4108M1A	Chitin-binding protein
HRD69_RS07175	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HRD69_RS07200	ENOG4105X5Z	General secretion pathway protein I
HRD69_RS07215	ENOG4105D7Q	type ii secretion system
HRD69_RS07220	ENOG4107QHF	type ii secretion system protein e
HRD69_RS07265	ENOG4108FKE	two-component system sensor kinase
HRD69_RS07270	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD69_RS07285	ENOG4105FTC	Lytic transglycosylase catalytic
HRD69_RS07305	ENOG4108RBT	type iii secretion
HRD69_RS07325	ENOG4108KB1	transcriptional regulator, arac family
HRD69_RS07335	ENOG4105X27	type iii secretion
HRD69_RS07340	ENOG4108HR8	type iii secretion
HRD69_RS07350	ENOG4108JIR	Flagellum-specific ATP synthase
HRD69_RS07385	ENOG4105EGS	Mechanosensitive ion channel
HRD69_RS07400	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD69_RS07405	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS07410	ENOG4105EHG	Permease protein
HRD69_RS07415	ENOG4107R4I	Periplasmic binding protein
HRD69_RS07420	ENOG4106QJH	hemin transport protein
HRD69_RS07425	ENOG4107ENK	receptor
HRD69_RS07430	ENOG4107F3C	Hemin uptake protein
HRD69_RS07435	ENOG41090JE	Utilization Protein
HRD69_RS07440	ENOG4105D4P	Coproporphyrinogen iii oxidase
HRD69_RS07450	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HRD69_RS07460	ENOG4105EJG	cellulose synthase
HRD69_RS07465	ENOG4107EEX	Cellulose synthase regulator protein
HRD69_RS07475	ENOG4105D1F	ATP-binding protein
HRD69_RS07485	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS07550	ENOG4108SIC	Transcriptional regulator
HRD69_RS07555	ENOG4105CNV	Aldolase
HRD69_RS07560	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HRD69_RS07565	ENOG4105BZW	Glycerate kinase
HRD69_RS07570	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HRD69_RS07575	ENOG4105CTX	dehydratase
HRD69_RS07580	ENOG4105DJB	Major Facilitator Superfamily
HRD69_RS07585	ENOG4105BZ8	glutamate synthase
HRD69_RS07590	ENOG4108RC0	Electron transport protein
HRD69_RS07595	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HRD69_RS07600	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HRD69_RS07610	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HRD69_RS07625	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HRD69_RS07630	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HRD69_RS07640	ENOG4108ZVF	(LipO)protein
HRD69_RS07645	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HRD69_RS07655	ENOG4108M1A	Chitin-binding protein
HRD69_RS07665	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HRD69_RS07670	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HRD69_RS07690	ENOG4105EGS	Mechanosensitive ion channel
HRD69_RS07695	ENOG4105DJ4	phosphatidylserine decarboxylase
HRD69_RS07700	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HRD69_RS07705	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HRD69_RS07725	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HRD69_RS07730	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HRD69_RS07735	ENOG4105K8N	protein family UPF0079, ATPase
HRD69_RS07740	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRD69_RS07745	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HRD69_RS07755	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HRD69_RS07760	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HRD69_RS07765	ENOG4107QJR	hflk protein
HRD69_RS07770	ENOG4105EPW	hflc protein
HRD69_RS07785	ENOG4105KPV	Transcriptional regulator
HRD69_RS07790	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HRD69_RS07795	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HRD69_RS07800	ENOG4105CSU	acyl-Coa dehydrogenase
HRD69_RS07805	ENOG4105WSB	biofilm stress and motility protein A
HRD69_RS07810	ENOG4108MXZ	Esterase
HRD69_RS07820	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HRD69_RS07845	ENOG4105FHY	Opacity-associated protein A
HRD69_RS07850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRD69_RS07860	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HRD69_RS07865	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HRD69_RS07870	ENOG4108UUE	Transcriptional regulator
HRD69_RS07875	ENOG41061GZ	Protein of unknown function (DUF1107)
HRD69_RS07880	ENOG4105C37	(CBS) domain
HRD69_RS07885	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HRD69_RS07890	ENOG4105CFU	surface antigen
HRD69_RS07900	ENOG4108ZHD	aig2 family
HRD69_RS07905	ENOG4105F0N	pyrophosphate phospho-hydrolase
HRD69_RS07910	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS07915	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HRD69_RS07920	ENOG4105DFU	Cell wall formation (By similarity)
HRD69_RS07940	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS07950	ENOG4105EAH	synthase
HRD69_RS07965	ENOG4105QYV	Membrane
HRD69_RS07970	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HRD69_RS07985	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HRD69_RS07995	ENOG4105HBR	Rna-binding protein
HRD69_RS08000	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HRD69_RS08005	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HRD69_RS08010	ENOG4105EEI	dihydropteroate synthase
HRD69_RS08020	ENOG4105NTZ	Preprotein translocase subunit SecG
HRD69_RS08040	ENOG4105CHV	Transcription elongation factor NusA
HRD69_RS08050	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HRD69_RS08055	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HRD69_RS08065	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HRD69_RS08080	ENOG4105C1J	atp-dependent rna helicase
HRD69_RS08085	ENOG4105DEN	Luciferase family
HRD69_RS08120	ENOG4108YYD	acetyltransferase
HRD69_RS08125	ENOG41082IR	Excinuclease ABC C subunit domain protein
HRD69_RS08130	ENOG4105D5Q	Arginine ornithine antiporter
HRD69_RS08135	ENOG4105CXN	decarboxylase
HRD69_RS08145	ENOG4108ZPB	UPF0306 protein
HRD69_RS08150	ENOG4105K4T	epimerase
HRD69_RS08155	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
HRD69_RS08160	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
HRD69_RS08165	ENOG4105FD8	phosphonate metabolism protein PhnM
HRD69_RS08170	ENOG4105HRV	phosphonate c-p lyase system protein phnl
HRD69_RS08175	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
HRD69_RS08180	ENOG4105FT8	Phosphonate metabolism
HRD69_RS08185	ENOG4105EKV	Phosphonate metabolism protein
HRD69_RS08190	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
HRD69_RS08195	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
HRD69_RS08200	ENOG4107RJJ	Transcriptional regulator
HRD69_RS08215	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HRD69_RS08220	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HRD69_RS08225	ENOG4108JQ7	(ABC) transporter
HRD69_RS08230	ENOG4105C3U	ABC transporter
HRD69_RS08235	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS08240	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS08250	ENOG4105XEP	YhcH YjgK YiaL family protein
HRD69_RS08260	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HRD69_RS08265	ENOG4108MJ3	acetyltransferase
HRD69_RS08275	ENOG4105MYG	DNA polymerase iii, chi subunit
HRD69_RS08280	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HRD69_RS08285	ENOG4108M8S	permease YjgP YjgQ family protein
HRD69_RS08290	ENOG4108K5H	permease YjgP YjgQ family protein
HRD69_RS08325	ENOG4108UHE	carbonic anhydrase
HRD69_RS08330	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS08350	ENOG4105RI1	glycoprotein receptor
HRD69_RS08370	ENOG41061GT	Aldolase
HRD69_RS08375	ENOG4105D4B	ABC, transporter
HRD69_RS08380	ENOG4105F5R	ABC transporter
HRD69_RS08385	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
HRD69_RS08390	ENOG4105C2J	ABC transporter
HRD69_RS08395	ENOG4105DKT	Transcriptional regulator
HRD69_RS08400	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
HRD69_RS08405	ENOG4105DKP	glycosyl transferase, family 9
HRD69_RS08415	ENOG4105D5Q	Arginine ornithine antiporter
HRD69_RS08420	ENOG4105CEU	Arginine dihydrolase
HRD69_RS08435	ENOG410624X	efflux transporter, rnd family, mfp subunit
HRD69_RS08440	ENOG4105BZS	acriflavin resistance protein
HRD69_RS08460	ENOG4105CMT	Dihydroxyacetone kinase
HRD69_RS08465	ENOG4108UTZ	Dihydroxyacetone kinase
HRD69_RS08470	ENOG4105VDH	Dihydroxyacetone kinase
HRD69_RS08505	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HRD69_RS08510	ENOG4105WBN	Transcriptional regulator (LacI family
HRD69_RS08525	ENOG4108M0B	Sucrose porin
HRD69_RS08530	ENOG4105D7K	pfkb domain protein
HRD69_RS08535	ENOG4105BZU	Histidine kinase
HRD69_RS08540	ENOG4105YBH	Protein of unknown function (DUF1435)
HRD69_RS08565	ENOG4105CPC	Aldo Keto reductase
HRD69_RS08585	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HRD69_RS08590	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HRD69_RS08595	ENOG4105K3G	Periplasmic Protein
HRD69_RS08605	ENOG4108NRW	Phospholipase, patatin family
HRD69_RS08610	ENOG4105EYA	deoxyribonuclease
HRD69_RS08615	ENOG4105D9N	nucleoside
HRD69_RS08630	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HRD69_RS08640	ENOG4105EUP	HipA domain protein
HRD69_RS08645	ENOG41062Z9	Membrane
HRD69_RS08650	ENOG4105EAC	phosphoserine phosphatase
HRD69_RS08655	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HRD69_RS08660	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HRD69_RS08665	ENOG4105CIS	alcohol dehydrogenase
HRD69_RS08670	ENOG4105CC0	LysR family Transcriptional regulator
HRD69_RS08680	ENOG4105C5H	ABC transporter
HRD69_RS08685	ENOG41090EK	ompa motb domain protein
HRD69_RS08690	ENOG4108KHX	Diguanylate cyclase
HRD69_RS08705	ENOG4107SC1	transglycosylase
HRD69_RS08710	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HRD69_RS08715	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRD69_RS08725	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD69_RS08730	ENOG4108RH0	Crea protein
HRD69_RS08735	ENOG41065U4	response regulator
HRD69_RS08750	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HRD69_RS08760	ENOG4105D1Q	UPF0246 protein
HRD69_RS08765	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD69_RS08770	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HRD69_RS08775	ENOG4105CSH	Transporter
HRD69_RS08785	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HRD69_RS08795	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HRD69_RS08805	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRD69_RS08810	ENOG41063Z6	transcriptional regulator, lysR family
HRD69_RS08830	ENOG4105DTN	riboflavin biosynthesis protein ribF
HRD69_RS08835	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HRD69_RS08840	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HRD69_RS08845	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HRD69_RS08850	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HRD69_RS08855	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HRD69_RS08865	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HRD69_RS08870	ENOG4108NIW	Leucine export protein LeuE
HRD69_RS08875	ENOG4105DWK	Membrane
HRD69_RS08885	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HRD69_RS08890	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HRD69_RS08895	ENOG4105NWN	ApaG protein
HRD69_RS08900	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HRD69_RS08915	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HRD69_RS08920	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HRD69_RS08930	ENOG4105D3G	Pseudouridine synthase
HRD69_RS08940	ENOG4105CQ2	DNA polymerase
HRD69_RS08945	ENOG4108KF1	Membrane
HRD69_RS08955	ENOG4106SMU	thiamine transporter membrane protein
HRD69_RS08960	ENOG4105DP9	ABC transporter
HRD69_RS08980	ENOG4105F1A	Pyruvate formate-lyase
HRD69_RS08990	ENOG4105S8Q	sugar efflux transporter
HRD69_RS09000	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HRD69_RS09005	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HRD69_RS09020	ENOG41064T2	transcriptional regulator, lysR family
HRD69_RS09025	ENOG4108IQE	Amp-dependent synthetase and ligase
HRD69_RS09030	ENOG4105C7K	acetolactate synthase
HRD69_RS09035	ENOG4108ZP8	Acetolactate synthase small subunit
HRD69_RS09040	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HRD69_RS09055	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HRD69_RS09060	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRD69_RS09065	ENOG4105CJN	penicillin-binding protein
HRD69_RS09070	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HRD69_RS09075	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HRD69_RS09080	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HRD69_RS09090	ENOG4105CNI	cell division protein FtsW
HRD69_RS09095	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HRD69_RS09100	ENOG4105DFU	Cell wall formation (By similarity)
HRD69_RS09110	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HRD69_RS09115	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HRD69_RS09120	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HRD69_RS09135	ENOG4108SR7	Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity)
HRD69_RS09140	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HRD69_RS09145	ENOG4105M6F	mutator MutT protein
HRD69_RS09150	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HRD69_RS09165	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HRD69_RS09170	ENOG4105D7Q	type ii secretion system
HRD69_RS09175	ENOG4107QHF	type ii secretion system protein e
HRD69_RS09180	ENOG4108ZUW	Major pilin subunit
HRD69_RS09185	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HRD69_RS09190	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD69_RS09195	ENOG4106A72	regulatory protein AmpE
HRD69_RS09205	ENOG4105C85	amino acid
HRD69_RS09210	ENOG41073TP	transcriptional regulator
HRD69_RS09215	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HRD69_RS09220	ENOG4107QSN	dihydrolipoamide acetyltransferase
HRD69_RS09225	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRD69_RS09235	ENOG4107RNH	Outer membrane receptor FepA
HRD69_RS09240	ENOG4107QIJ	Aconitate hydratase 2
HRD69_RS09245	ENOG4108ZIG	UPF0231 protein
HRD69_RS09300	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HRD69_RS09305	ENOG4108ZRK	uncharacterized protein yacC
HRD69_RS09310	ENOG4105E3B	Multicopper oxidase
HRD69_RS09320	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HRD69_RS09325	ENOG41077A9	carbonic anhydrase
HRD69_RS09330	ENOG4105DA5	(ABC) transporter
HRD69_RS09335	ENOG4105E3A	(ABC) transporter
HRD69_RS09340	ENOG4107BJW	polysaccharide deacetylase
HRD69_RS09345	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HRD69_RS09355	ENOG4105J12	Multidrug resistance protein mdtN
HRD69_RS09360	ENOG4108MI0	Resistance protein
HRD69_RS09365	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HRD69_RS09370	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HRD69_RS09375	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRD69_RS09385	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HRD69_RS09390	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRD69_RS09395	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HRD69_RS09400	ENOG4107XID	2'-5' rna ligase
HRD69_RS09405	ENOG4105CQ7	ATP-dependent helicase
HRD69_RS09410	ENOG4105BZ4	penicillin-binding protein
HRD69_RS09415	ENOG4105E0A	ABC, transporter
HRD69_RS09420	ENOG4105J76	Periplasmic binding protein
HRD69_RS09425	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HRD69_RS09435	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HRD69_RS09445	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HRD69_RS09455	ENOG4105EN6	Membrane
HRD69_RS09465	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HRD69_RS09470	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HRD69_RS09475	ENOG4105C0H	protease
HRD69_RS09480	ENOG4105BZU	Histidine kinase
HRD69_RS09485	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRD69_RS09490	ENOG4105DXN	mazG family
HRD69_RS09495	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HRD69_RS09500	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HRD69_RS09515	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HRD69_RS09520	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HRD69_RS09525	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HRD69_RS09530	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HRD69_RS09535	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HRD69_RS09550	ENOG4108MXK	alkaline phosphatase isozyme conversion
HRD69_RS09555	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD69_RS09560	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HRD69_RS09565	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HRD69_RS09570	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HRD69_RS09575	ENOG4105N0Z	inner membrane protein ygbE
HRD69_RS09580	ENOG4108YZG	isomerase
HRD69_RS09585	ENOG4105CPQ	Dehydrogenase
HRD69_RS09590	ENOG4105IE8	Alpha-ketoglutarate permease
HRD69_RS09595	ENOG4105CHR	reductase
HRD69_RS09600	ENOG4105CMT	Dihydroxyacetone kinase
HRD69_RS09605	ENOG4108UTZ	Dihydroxyacetone kinase
HRD69_RS09610	ENOG4105DKT	Transcriptional regulator
HRD69_RS09615	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRD69_RS09625	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HRD69_RS09630	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HRD69_RS09635	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HRD69_RS09640	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HRD69_RS09645	ENOG4108K5P	(LipO)protein
HRD69_RS09650	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD69_RS09655	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HRD69_RS09675	ENOG4108RQP	Major type 1 subunit fimbrin
HRD69_RS09680	ENOG4106PG1	outer membrane usher protein
HRD69_RS09685	ENOG4108FZ9	Chaperone
HRD69_RS09695	ENOG4105UGQ	Fimbrial
HRD69_RS09700	ENOG4105H8W	Fimbrial protein
HRD69_RS09725	ENOG4108JJA	ABC, transporter
HRD69_RS09730	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD69_RS09740	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HRD69_RS09760	ENOG4105CHR	reductase
HRD69_RS09775	ENOG4105F87	Dehydratase
HRD69_RS09785	ENOG41066YJ	Beta-lactamase
HRD69_RS09790	ENOG4105CXK	mandelate racemase muconate lactonizing
HRD69_RS09795	ENOG4105DEF	Extracellular solute-binding protein, family 5
HRD69_RS09800	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS09805	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS09815	ENOG4108JQ7	(ABC) transporter
HRD69_RS09820	ENOG4105QFC	Hsc56 co-chaperone of HscC
HRD69_RS09825	ENOG4105F7F	Chaperone
HRD69_RS09830	ENOG4105EAB	amino acid AbC transporter
HRD69_RS09835	ENOG4105E5Q	amino acid AbC transporter
HRD69_RS09840	ENOG4105E5Q	amino acid AbC transporter
HRD69_RS09845	ENOG4105CDA	abc transporter atp-binding protein
HRD69_RS09850	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HRD69_RS09865	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HRD69_RS09870	ENOG4105YVS	arsR family transcriptional regulator
HRD69_RS09875	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
HRD69_RS09880	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD69_RS09885	ENOG4105ETZ	PTS System
HRD69_RS09890	ENOG4105KPI	PTS system sorbose subfamily IIB component
HRD69_RS09895	ENOG4108XCU	pts system
HRD69_RS09900	ENOG4105DKT	Transcriptional regulator
HRD69_RS09905	ENOG4107GFK	fumarate
HRD69_RS09920	ENOG4105C2J	ABC transporter
HRD69_RS09925	ENOG4105CNN	ABC, transporter
HRD69_RS09930	ENOG4108HHA	Transketolase
HRD69_RS09935	ENOG4108IUS	Transketolase
HRD69_RS09940	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HRD69_RS09965	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HRD69_RS09970	ENOG4105Y3E	Modulates RecA activity (By similarity)
HRD69_RS09975	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HRD69_RS10005	ENOG4107VXZ	Hydrolase
HRD69_RS10010	ENOG4105W39	Membrane
HRD69_RS10015	ENOG4105D9M	gamma-glutamylcysteine synthetase
HRD69_RS10020	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HRD69_RS10025	ENOG4108JU6	CBS domain protein
HRD69_RS10030	ENOG4106KVJ	cytochrome C assembly protein
HRD69_RS10035	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRD69_RS10045	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HRD69_RS10055	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HRD69_RS10060	ENOG4108NE3	Salt-induced outer membrane protein
HRD69_RS10065	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HRD69_RS10070	ENOG4108NEV	two component transcriptional regulator, LytTR family
HRD69_RS10075	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD69_RS10080	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
HRD69_RS10085	ENOG4105CQC	Prephenate dehydratase
HRD69_RS10090	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HRD69_RS10095	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRD69_RS10100	ENOG4105C34	Pseudouridine synthase
HRD69_RS10105	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HRD69_RS10110	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD69_RS10155	ENOG4105JIM	Phosphatidylserine synthase
HRD69_RS10160	ENOG4105CD5	CoA-binding domain protein
HRD69_RS10165	ENOG4106IUH	DTW domain containing protein
HRD69_RS10170	ENOG4105K63	Thioredoxin
HRD69_RS10175	ENOG4105EIB	trna rrna methyltransferase
HRD69_RS10180	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD69_RS10185	ENOG4105CW7	secretion protein, HlyD family
HRD69_RS10190	ENOG4105NTK	Transcriptional repressor Mpra
HRD69_RS10195	ENOG4105ZED	uncharacterized protein ygaH
HRD69_RS10200	ENOG4108UMN	azlc family
HRD69_RS10215	ENOG4105CHM	Aminotransferase
HRD69_RS10220	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HRD69_RS10230	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HRD69_RS10240	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
HRD69_RS10255	ENOG4106YJS	accessory processing protein
HRD69_RS10260	ENOG4107QPN	acyl-Coa dehydrogenase
HRD69_RS10270	ENOG4105E7A	Glutamine amidotransferase
HRD69_RS10275	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
HRD69_RS10280	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD69_RS10285	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD69_RS10290	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD69_RS10295	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD69_RS10300	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HRD69_RS10305	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HRD69_RS10310	ENOG4105CJ2	(LipO)protein
HRD69_RS10325	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HRD69_RS10330	ENOG4105CIN	aminoacyl-histidine dipeptidase
HRD69_RS10340	ENOG4105V1F	Fermentation respiration switch protein
HRD69_RS10345	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
HRD69_RS10355	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HRD69_RS10365	ENOG4105E2V	Glycosyltransferase 36
HRD69_RS10390	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRD69_RS10395	ENOG4105NBK	UPF0345 protein
HRD69_RS10400	ENOG4105DH7	May be involved in recombination (By similarity)
HRD69_RS10405	ENOG4105DKQ	ROK family
HRD69_RS10410	ENOG4105EYH	Exonuclease
HRD69_RS10415	ENOG4107RH8	nuclease SbcCD subunit D
HRD69_RS10420	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRD69_RS10425	ENOG4105BZU	Histidine kinase
HRD69_RS10430	ENOG4105DJH	phosphate
HRD69_RS10435	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HRD69_RS10440	ENOG4105C85	amino acid
HRD69_RS10445	ENOG4107R28	alpha amylase, catalytic region
HRD69_RS10450	ENOG4105CHR	reductase
HRD69_RS10460	ENOG41074AV	Hok/gef family
HRD69_RS10465	ENOG4105D3R	alkyl hydroperoxide reductase
HRD69_RS10470	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HRD69_RS10475	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HRD69_RS10485	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HRD69_RS10490	ENOG4105VIE	preprotein translocase, subunit YajC
HRD69_RS10495	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRD69_RS10500	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRD69_RS10505	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HRD69_RS10510	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HRD69_RS10515	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HRD69_RS10525	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HRD69_RS10530	ENOG4108ZAI	phosphatidylglycerophosphatase a
HRD69_RS10535	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HRD69_RS10540	ENOG4105CTB	Polyprenyl synthetase
HRD69_RS10550	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HRD69_RS10555	ENOG4107S0N	DJ-1 family
HRD69_RS10560	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HRD69_RS10565	ENOG4108VPT	UPF0234 protein
HRD69_RS10570	ENOG4107RDB	Major Facilitator
HRD69_RS10575	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HRD69_RS10580	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HRD69_RS10585	ENOG4105CCU	oxidase (Subunit III)
HRD69_RS10590	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HRD69_RS10595	ENOG4105E2S	oxidase) subunit II
HRD69_RS10600	ENOG4108NFH	Sugar hydrolase
HRD69_RS10605	ENOG4105EYM	Major Facilitator superfamily
HRD69_RS10610	ENOG4105IEY	(LipO)protein
HRD69_RS10615	ENOG4105M85	Bola protein
HRD69_RS10620	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HRD69_RS10625	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HRD69_RS10630	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HRD69_RS10635	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HRD69_RS10640	ENOG4105K70	DNA-binding protein
HRD69_RS10645	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HRD69_RS10650	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HRD69_RS10655	ENOG4108TGP	Thioesterase superfamily protein
HRD69_RS10660	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HRD69_RS10665	ENOG4108NFA	extracellular solute-binding protein
HRD69_RS10670	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HRD69_RS10680	ENOG4108XM1	transcriptional regulator AsnC family
HRD69_RS10685	ENOG4105BZ1	(ABC) transporter
HRD69_RS10690	ENOG4105BZ1	(ABC) transporter
HRD69_RS10695	ENOG4108YZA	Nitrogen regulatory protein pii
HRD69_RS10700	ENOG4105BZU	Histidine kinase
HRD69_RS10705	ENOG4105C29	acyl-CoA thioesterase
HRD69_RS10710	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HRD69_RS10715	ENOG41080UX	Methyltransferase
HRD69_RS10725	ENOG4105KF5	hemolysin expression-modulating protein
HRD69_RS10730	ENOG4108UKR	Biofilm formation regulator YbaJ
HRD69_RS10740	ENOG4105DIK	(ABC) transporter
HRD69_RS10745	ENOG4105CC5	ABC transporter
HRD69_RS10750	ENOG4105DSE	periplasmic solute binding protein
HRD69_RS10755	ENOG4105YK5	50S ribosomal protein L36
HRD69_RS10760	ENOG4105NRA	50s ribosomal protein l31 type b
HRD69_RS10765	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HRD69_RS10770	ENOG4108626	Racemase
HRD69_RS10775	ENOG4105BZS	acriflavin resistance protein
HRD69_RS10780	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HRD69_RS10785	ENOG4107XI7	Tetr family transcriptional regulator
HRD69_RS10790	ENOG41090EX	DsrE family
HRD69_RS10795	ENOG4105EGS	Mechanosensitive ion channel
HRD69_RS10800	ENOG4106428	Protein of unknown function (DUF2496)
HRD69_RS10810	ENOG4105WD1	Membrane
HRD69_RS10815	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HRD69_RS10820	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HRD69_RS10830	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HRD69_RS10835	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HRD69_RS10840	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HRD69_RS10845	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HRD69_RS10850	ENOG4108EX3	reductase
HRD69_RS10855	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HRD69_RS10860	ENOG4105FAW	cDP-glucose 4,6-dehydratase
HRD69_RS10865	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD69_RS10870	ENOG4108SMP	Nad-dependent epimerase dehydratase
HRD69_RS10875	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HRD69_RS10910	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HRD69_RS10915	ENOG4105C30	Nad-dependent epimerase dehydratase
HRD69_RS10920	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HRD69_RS10930	ENOG4107QKV	phosphomannomutase
HRD69_RS10935	ENOG4108QY5	Ferric enterobactin transport protein
HRD69_RS10940	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HRD69_RS10950	ENOG4105EY8	ABC transporter
HRD69_RS10955	ENOG4108SHN	Glycosyl transferase, family 2
HRD69_RS10965	ENOG4105CKK	Glycosyl transferase, family 2
HRD69_RS10970	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HRD69_RS10980	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HRD69_RS10985	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HRD69_RS10990	ENOG4105CK5	oxidoreductase
HRD69_RS11000	ENOG4108S0S	Nucleotidyl transferase
HRD69_RS11010	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HRD69_RS11015	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD69_RS11030	ENOG4107RE1	Inosine-guanosine kinase
HRD69_RS11035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HRD69_RS11040	ENOG4105EU0	Major facilitator Superfamily
HRD69_RS11045	ENOG4105CGH	5'-nucleotidase
HRD69_RS11055	ENOG4108Z66	YbaK ebsC protein
HRD69_RS11060	ENOG4105MBR	gumn family
HRD69_RS11065	ENOG4105C59	p-type ATPase
HRD69_RS11070	ENOG4108Z6Z	Transcriptional regulator
HRD69_RS11075	ENOG4105G5H	Membrane
HRD69_RS11080	ENOG4107QX8	SPFH domain, Band 7 family protein
HRD69_RS11085	ENOG4107QR8	Thioredoxin
HRD69_RS11090	ENOG4105E1F	short-chain dehydrogenase reductase
HRD69_RS11095	ENOG4108UJV	acyl-CoA thioesterase i
HRD69_RS11100	ENOG4108I0Y	(ABC) transporter
HRD69_RS11105	ENOG4105CV6	ABC transporter, permease
HRD69_RS11110	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HRD69_RS11115	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HRD69_RS11120	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HRD69_RS11125	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HRD69_RS11130	ENOG4105C8N	cysteinyl-tRNA synthetase
HRD69_RS11135	ENOG4105WQ3	Rna-binding protein
HRD69_RS11140	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HRD69_RS11150	ENOG4105DFP	Integrase
HRD69_RS11195	ENOG4108R1E	Serine threonine protein phosphatase 1
HRD69_RS11205	ENOG4108N8T	regulatoR
HRD69_RS11225	ENOG4105BZU	Histidine kinase
HRD69_RS11230	ENOG410607N	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity)
HRD69_RS11235	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HRD69_RS11240	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HRD69_RS11245	ENOG4108Z43	UPF0250 protein
HRD69_RS11250	ENOG4105DZ1	carboxypeptidase
HRD69_RS11255	ENOG4105K6T	rare lipoprotein A
HRD69_RS11260	ENOG4105CNI	cell division protein FtsW
HRD69_RS11265	ENOG4105CJN	penicillin-binding protein
HRD69_RS11275	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HRD69_RS11280	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HRD69_RS11285	ENOG4105DJF	DNA polymerase III, delta' subunit
HRD69_RS11290	ENOG4108U2H	Rare lipoprotein B
HRD69_RS11295	ENOG4105C8T	Leucyl-tRNA synthetase
HRD69_RS11300	ENOG4107PAI	alpha helical protein
HRD69_RS11305	ENOG4105CDA	abc transporter atp-binding protein
HRD69_RS11310	ENOG4105DRP	amino acid AbC transporter
HRD69_RS11315	ENOG4105EAD	ABC transporter
HRD69_RS11320	ENOG4107RP9	extracellular solute-binding protein, family 3
HRD69_RS11330	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HRD69_RS11335	ENOG4108JU5	Magnesium and cobalt efflux protein
HRD69_RS11340	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HRD69_RS11345	ENOG4105C9A	Phoh family
HRD69_RS11350	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HRD69_RS11355	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRD69_RS11390	ENOG4105CAQ	asparagine synthetase
HRD69_RS11395	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HRD69_RS11400	ENOG4105E2R	ROK family
HRD69_RS11405	ENOG4105CE4	GlcNAc 6-P deacetylase
HRD69_RS11415	ENOG4105CI1	PTS System
HRD69_RS11420	ENOG4105CX6	glutaminyL-tRNA synthetase
HRD69_RS11435	ENOG41090R7	Ferric uptake
HRD69_RS11440	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HRD69_RS11445	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS11450	ENOG4105NNH	LexA regulated protein
HRD69_RS11455	ENOG4105EV9	Alpha Beta Hydrolase
HRD69_RS11465	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HRD69_RS11480	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HRD69_RS11485	ENOG4105C08	Histidine kinase
HRD69_RS11495	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HRD69_RS11500	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HRD69_RS11510	ENOG4105XIQ	Protein of unknown function (DUF2517)
HRD69_RS11515	ENOG4107SEY	Conserved Protein
HRD69_RS11520	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HRD69_RS11525	ENOG4107RF4	Phosphodiesterase
HRD69_RS11530	ENOG4107QNR	UPF0135 protein
HRD69_RS11535	ENOG4105P4J	Allophanate hydrolase, subunit 1
HRD69_RS11540	ENOG4107R7A	Allophanate hydrolase subunit 2
HRD69_RS11545	ENOG4105E7W	lamb ycsf family protein
HRD69_RS11565	ENOG4105BZN	citrate synthase
HRD69_RS11570	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HRD69_RS11575	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HRD69_RS11585	ENOG4105E33	succinate dehydrogenase
HRD69_RS11590	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HRD69_RS11595	ENOG4105C7S	Dehydrogenase
HRD69_RS11605	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HRD69_RS11610	ENOG4105CGH	5'-nucleotidase
HRD69_RS11615	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD69_RS11620	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD69_RS11630	ENOG4105KJB	cyd operon protein YbgE
HRD69_RS11635	ENOG4107YD3	Thioesterase
HRD69_RS11640	ENOG4105E02	MotA TolQ exbB proton channel
HRD69_RS11650	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HRD69_RS11650	ENOG4108Z82	Cell envelope integrity inner membrane protein TolA
HRD69_RS11655	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HRD69_RS11660	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HRD69_RS11665	ENOG4105UFD	tol-pal system protein YbgF
HRD69_RS11700	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HRD69_RS11705	ENOG4105PGM	cation diffusion facilitator family transporter
HRD69_RS11710	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD69_RS11715	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRD69_RS11720	ENOG4105VIF	phosphate starvation-inducible protein
HRD69_RS11725	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HRD69_RS11730	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HRD69_RS11735	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HRD69_RS11740	ENOG4105CMR	udp-glucose 4-epimerase
HRD69_RS11750	ENOG4105DKW	ABC transporter
HRD69_RS11755	ENOG4105F4R	Transcriptional regulator mode
HRD69_RS11765	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HRD69_RS11770	ENOG4105E0C	molybdate abc transporter
HRD69_RS11780	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HRD69_RS11790	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HRD69_RS11795	ENOG4107P2S	Transcriptional regulator
HRD69_RS11800	ENOG4105C6K	Malic enzyme
HRD69_RS11810	ENOG4105PQ6	UPF0208 membrane protein
HRD69_RS11815	ENOG4105XWI	UPF0304 protein
HRD69_RS11820	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
HRD69_RS11825	ENOG4107QWE	)-transporter
HRD69_RS11830	ENOG4105DK2	UPF0207 protein
HRD69_RS11835	ENOG4105CHM	Aminotransferase
HRD69_RS11840	ENOG4107NQ8	LysR family Transcriptional regulator
HRD69_RS11845	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRD69_RS11850	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD69_RS11855	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD69_RS11860	ENOG4105GKE	subunit e
HRD69_RS11865	ENOG4107QIZ	NADH dehydrogenase
HRD69_RS11870	ENOG4108IEH	NADH dehydrogenase subunit g
HRD69_RS11875	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HRD69_RS11880	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD69_RS11885	ENOG4107UFS	subunit j
HRD69_RS11890	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD69_RS11895	ENOG4105D65	subunit l
HRD69_RS11900	ENOG4105C8S	subunit m
HRD69_RS11905	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD69_RS11925	ENOG4108R66	Conserved Protein
HRD69_RS11930	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HRD69_RS11935	ENOG4105CHR	reductase
HRD69_RS11940	ENOG4105K2J	Transcriptional regulator
HRD69_RS11945	ENOG4105C5I	Dehydrogenase
HRD69_RS11960	ENOG4105C01	Dihydroxy-acid dehydratase
HRD69_RS11965	ENOG4105TNS	Conserved Protein
HRD69_RS11980	ENOG4105E4F	Isochorismate synthase
HRD69_RS11985	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HRD69_RS11995	ENOG4108IPT	Naphthoate synthase
HRD69_RS12000	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HRD69_RS12005	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD69_RS12015	ENOG4105CH6	catalase
HRD69_RS12020	ENOG4108UII	YfaZ family
HRD69_RS12025	ENOG4105E0U	tyrosine-specific transport protein
HRD69_RS12045	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
HRD69_RS12050	ENOG4105XPH	Ferredoxin
HRD69_RS12055	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD69_RS12060	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRD69_RS12065	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HRD69_RS12070	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRD69_RS12075	ENOG4105BZU	Histidine kinase
HRD69_RS12080	ENOG41068CG	regulatoR
HRD69_RS12085	ENOG4105E3G	Phosphotransfer intermediate protein in two-component regulatory system with RcsBC
HRD69_RS12090	ENOG4106UW1	Major Facilitator superfamily
HRD69_RS12105	ENOG4105BZ1	(ABC) transporter
HRD69_RS12110	ENOG4107QZV	Type I secretion membrane fusion protein
HRD69_RS12115	ENOG4105FCK	Membrane
HRD69_RS12120	ENOG4108DG9	Smr protein MutS2
HRD69_RS12125	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HRD69_RS12130	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HRD69_RS12135	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
HRD69_RS12140	ENOG4105EJ9	Membrane
HRD69_RS12145	ENOG4108BPE	-transporting atpase
HRD69_RS12150	ENOG4105MH2	YfcL protein
HRD69_RS12155	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HRD69_RS12160	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD69_RS12175	ENOG4105D6F	Phosphatase
HRD69_RS12180	ENOG4105F4P	)-transporter
HRD69_RS12185	ENOG4106WZ1	flagella biosynthesis regulator
HRD69_RS12195	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HRD69_RS12205	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRD69_RS12220	ENOG410631K	Membrane
HRD69_RS12235	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRD69_RS12245	ENOG4105DQR	SNARE associated Golgi
HRD69_RS12255	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HRD69_RS12260	ENOG4108S3P	Sporulation domain protein
HRD69_RS12265	ENOG4105E96	Colicin v production protein
HRD69_RS12270	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HRD69_RS12275	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HRD69_RS12280	ENOG4105E89	ABC transporter
HRD69_RS12285	ENOG4105DSP	amino acid AbC transporter
HRD69_RS12290	ENOG4106YG3	ABC transporter
HRD69_RS12295	ENOG4108JEH	abc transporter atp-binding protein
HRD69_RS12300	ENOG4105ECP	epimerase
HRD69_RS12310	ENOG4108RE9	Phosphodiesterase
HRD69_RS12315	ENOG4105PTV	Nudix Hydrolase
HRD69_RS12320	ENOG4108K4B	hydrolase
HRD69_RS12325	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HRD69_RS12335	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HRD69_RS12340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRD69_RS12345	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD69_RS12360	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HRD69_RS12365	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HRD69_RS12370	ENOG4105CHW	UPF0052 protein
HRD69_RS12375	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRD69_RS12380	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRD69_RS12385	ENOG4105M00	molybdopterin converting factor, subunit 1
HRD69_RS12390	ENOG4108ZAF	Molybdopterin
HRD69_RS12395	ENOG4105HFZ	Membrane
HRD69_RS12400	ENOG4107QWP	ABC-2 type transporter
HRD69_RS12405	ENOG4107QWP	ABC-2 type transporter
HRD69_RS12410	ENOG4105CJ1	ABC, transporter
HRD69_RS12415	ENOG4105D0S	secretion protein (HlyD
HRD69_RS12420	ENOG4107MVR	Transcriptional regulator
HRD69_RS12425	ENOG4105C1J	atp-dependent rna helicase
HRD69_RS12430	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HRD69_RS12445	ENOG41061WM	D-Alanyl-D-Alanine
HRD69_RS12450	ENOG4105CXG	d-lactate dehydrogenase
HRD69_RS12460	ENOG4105N1F	Hnh endonuclease
HRD69_RS12470	ENOG4105Y3U	Transglycosylase-associated protein
HRD69_RS12480	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
HRD69_RS12495	ENOG4108W15	Protein of unknown function (DUF1456)
HRD69_RS12500	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HRD69_RS12505	ENOG4105C32	Amino acid ABC transporter (Permease)
HRD69_RS12510	ENOG4105CNN	ABC, transporter
HRD69_RS12515	ENOG4105C0Z	ABC transporter
HRD69_RS12520	ENOG4108IV0	ABC, transporter
HRD69_RS12525	ENOG4105KHC	sulfurtransferase
HRD69_RS12540	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
HRD69_RS12545	ENOG4107T5X	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS12550	ENOG4108IJ8	ABC transporter
HRD69_RS12555	ENOG4105WJV	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS12570	ENOG4105FDR	Membrane
HRD69_RS12585	ENOG4105DVT	helicase
HRD69_RS12590	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD69_RS12595	ENOG4108MTB	glycosyl transferase family
HRD69_RS12600	ENOG4105RC8	Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction
HRD69_RS12605	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
HRD69_RS12610	ENOG4107SDU	Methyl-accepting chemotaxis
HRD69_RS12615	ENOG4105CDA	abc transporter atp-binding protein
HRD69_RS12620	ENOG4105E5Q	amino acid AbC transporter
HRD69_RS12625	ENOG4107R0W	ABC transporter
HRD69_RS12630	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
HRD69_RS12635	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HRD69_RS12665	ENOG4108T1M	outer membrane protein x
HRD69_RS12685	ENOG4105C5H	ABC transporter
HRD69_RS12690	ENOG4105D06	uba thif-type nad fad binding protein
HRD69_RS12695	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HRD69_RS12705	ENOG4105CSH	Transporter
HRD69_RS12710	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD69_RS12735	ENOG4105EGI	Transcriptional regulator
HRD69_RS12740	ENOG4105CBP	Major Facilitator
HRD69_RS12745	ENOG4105EUJ	GTP cyclohydrolase i
HRD69_RS12750	ENOG4105DHF	Membrane
HRD69_RS12755	ENOG41060NJ	transcriptional regulator
HRD69_RS12770	ENOG4107SDZ	Galactoside transport system permease protein mglC
HRD69_RS12775	ENOG4108JUA	Transcriptional regulator
HRD69_RS12780	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HRD69_RS12785	ENOG4108RC0	Electron transport protein
HRD69_RS12790	ENOG4108MG9	hydrogenase 3 maturation protease
HRD69_RS12795	ENOG4105I6X	formate hydrogenlyase maturation
HRD69_RS12800	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HRD69_RS12810	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRD69_RS12815	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HRD69_RS12820	ENOG4107WQX	hydrogenase 4 membrane subunit
HRD69_RS12825	ENOG4105D65	subunit l
HRD69_RS12830	ENOG4107TDF	Formate hydrogenlyase subunit 4
HRD69_RS12835	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HRD69_RS12840	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HRD69_RS12845	ENOG410816D	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HRD69_RS12855	ENOG4107GZ4	SanA protein
HRD69_RS12860	ENOG4107R1I	NAD-dependent malic enzyme
HRD69_RS12870	ENOG41067MG	lrgb family
HRD69_RS12875	ENOG4105VAW	lrga family
HRD69_RS12880	ENOG4105E5W	Transporter
HRD69_RS12895	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HRD69_RS12900	ENOG4105D1F	ATP-binding protein
HRD69_RS12905	ENOG4105DBI	uridine monophosphokinase
HRD69_RS12915	ENOG4108GAE	asmA family
HRD69_RS12920	ENOG4105CEE	C4-dicarboxylate transporter
HRD69_RS12925	ENOG4105EE5	Membrane protein terC
HRD69_RS12930	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRD69_RS12935	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRD69_RS12940	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HRD69_RS12945	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HRD69_RS12965	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HRD69_RS12970	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HRD69_RS12975	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HRD69_RS12980	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HRD69_RS12990	ENOG4107SRH	Nad-dependent epimerase dehydratase
HRD69_RS12995	ENOG4105CNN	ABC, transporter
HRD69_RS13000	ENOG4105C2J	ABC transporter
HRD69_RS13005	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
HRD69_RS13010	ENOG4105CUB	amino acid
HRD69_RS13015	ENOG4105CJB	Exodeoxyribonuclease I
HRD69_RS13025	ENOG4105DR8	Membrane
HRD69_RS13030	ENOG41090HJ	UPF0265 protein
HRD69_RS13040	ENOG4105CNN	ABC, transporter
HRD69_RS13050	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HRD69_RS13055	ENOG4105JZC	GHMP kinase
HRD69_RS13060	ENOG4107QZB	decarboxylase
HRD69_RS13065	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRD69_RS13070	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HRD69_RS13075	ENOG4105KTW	ethanolamine utilization protein
HRD69_RS13080	ENOG4105M3W	utilization protein
HRD69_RS13090	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
HRD69_RS13100	ENOG4108EKI	Dehydrogenase
HRD69_RS13110	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HRD69_RS13120	ENOG4108VPX	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate (By similarity)
HRD69_RS13125	ENOG4105KNY	Microcompartments protein
HRD69_RS13130	ENOG4105KNY	Microcompartments protein
HRD69_RS13140	ENOG41084PW	diol glycerol dehydratase reactivating factor large subunit
HRD69_RS13145	ENOG4108ZFT	Dehydratase small subunit
HRD69_RS13150	ENOG4105YCI	dehydratase medium subunit
HRD69_RS13155	ENOG4105DMB	glycerol dehydratase
HRD69_RS13160	ENOG4105EHR	propanediol utilization protein pduB
HRD69_RS13165	ENOG4105KNY	Microcompartments protein
HRD69_RS13170	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HRD69_RS13175	ENOG4107XVH	Transcriptional regulator
HRD69_RS13180	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HRD69_RS13185	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HRD69_RS13190	ENOG41081F0	Precorrin-8x methylmutase
HRD69_RS13195	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
HRD69_RS13200	ENOG4108DR9	Cobalt-precorrin-6Y C(5)-methyltransferase
HRD69_RS13205	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
HRD69_RS13210	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HRD69_RS13215	ENOG4108P62	biosynthesis protein (CbiG)
HRD69_RS13220	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HRD69_RS13225	ENOG4105QUC	reductase
HRD69_RS13230	ENOG4107PPM	cobalt chelatase
HRD69_RS13235	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HRD69_RS13240	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
HRD69_RS13250	ENOG4108V4M	Cobalt abc transporter
HRD69_RS13260	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HRD69_RS13265	ENOG4108YZT	Adenosylcobinamide kinase
HRD69_RS13270	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HRD69_RS13275	ENOG4108TGR	phosphatase
HRD69_RS13280	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HRD69_RS13285	ENOG4105CN8	Transcriptional regulator
HRD69_RS13295	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HRD69_RS13300	ENOG4105EAA	nucleoside
HRD69_RS13310	ENOG4105UQX	Mate efflux family protein
HRD69_RS13320	ENOG4105C5H	ABC transporter
HRD69_RS13325	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HRD69_RS13330	ENOG4105D3G	Pseudouridine synthase
HRD69_RS13340	ENOG4105FE9	pseudouridine synthase
HRD69_RS13345	ENOG4108VCD	Chaperone
HRD69_RS13360	ENOG4105GQR	Chaperone
HRD69_RS13370	ENOG4105BZU	Histidine kinase
HRD69_RS13375	ENOG4108Q9V	regulatoR
HRD69_RS13385	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS13390	ENOG4107RCV	ABC transporter, permease
HRD69_RS13395	ENOG4105C4Y	ABC transporter
HRD69_RS13400	ENOG4105CXY	transporter
HRD69_RS13405	ENOG4105BZU	Histidine kinase
HRD69_RS13410	ENOG4108KX4	response regulator
HRD69_RS13415	ENOG4106YYS	transcriptional regulatory protein
HRD69_RS13420	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HRD69_RS13425	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
HRD69_RS13430	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
HRD69_RS13435	ENOG4105CI0	Citrate lyase
HRD69_RS13440	ENOG4105CHY	citrate lyase, alpha
HRD69_RS13455	ENOG4107QPK	)-transporter
HRD69_RS13460	ENOG4108TSE	Transferase
HRD69_RS13475	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HRD69_RS13485	ENOG4105D6F	Phosphatase
HRD69_RS13490	ENOG41061EV	selenium-binding protein YdfZ
HRD69_RS13500	ENOG4105J0Q	Transcriptional regulator
HRD69_RS13505	ENOG4105GSJ	Inner membrane protein ylaC
HRD69_RS13515	ENOG4105CNT	hydrolase family 2
HRD69_RS13520	ENOG4105ETE	Transcriptional regulator (LacI family
HRD69_RS13530	ENOG4105VZF	DsrB protein
HRD69_RS13535	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS13540	ENOG4105KT7	mgtC SapB transporter
HRD69_RS13545	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HRD69_RS13550	ENOG4108VA4	Universal stress protein
HRD69_RS13555	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HRD69_RS13560	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HRD69_RS13565	ENOG4107RD7	Flagellar Motor Protein, MotA
HRD69_RS13570	ENOG4105ER2	Ompa motb domain protein
HRD69_RS13575	ENOG4105CBS	Chea signal transduction histidine kinase
HRD69_RS13580	ENOG4108V3W	Chemotaxis protein, CheW
HRD69_RS13585	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS13590	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS13595	ENOG4105BZU	Histidine kinase
HRD69_RS13605	ENOG4108VYJ	response regulator receiver protein
HRD69_RS13610	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HRD69_RS13615	ENOG4105D00	flagellar biosynthetic protein flhB
HRD69_RS13620	ENOG4105D7B	Flagellar biosynthesis protein flha
HRD69_RS13625	ENOG4105W13	flagellar protein
HRD69_RS13635	ENOG4105QVD	Flagella synthesis protein FlgN
HRD69_RS13640	ENOG4105M9M	anti-sigma28 factor FlgM
HRD69_RS13645	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
HRD69_RS13650	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HRD69_RS13655	ENOG4108ZC9	flagellar basal-body rod protein flgc
HRD69_RS13660	ENOG4105W00	Flagellar hook capping protein
HRD69_RS13665	ENOG4105BZE	flagellar hook protein, FlgE
HRD69_RS13670	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HRD69_RS13675	ENOG4105CGA	flagellar basal-body rod protein FlgG
HRD69_RS13690	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HRD69_RS13700	ENOG4105E1Q	flagellar hook-associated protein
HRD69_RS13705	ENOG4105DTJ	flagellar hook-associated protein
HRD69_RS13710	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HRD69_RS13715	ENOG4105VS8	Flagellar biosynthetic protein fliq
HRD69_RS13720	ENOG4105CN7	Flagellar biosynthetic protein FliP
HRD69_RS13730	ENOG4105DD5	Flagellar motor switch protein
HRD69_RS13735	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD69_RS13740	ENOG4107ZI8	flagellar basal body-associated protein flil
HRD69_RS13745	ENOG4105WF4	Flagellar hook-length control protein
HRD69_RS13750	ENOG4105GSA	Flagellar export protein flij
HRD69_RS13755	ENOG4108JIR	Flagellum-specific ATP synthase
HRD69_RS13760	ENOG41090PJ	Flagellar assembly protein
HRD69_RS13765	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRD69_RS13770	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HRD69_RS13775	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HRD69_RS13785	ENOG4105DHT	Metal Dependent Phosphohydrolase
HRD69_RS13790	ENOG4108NKV	transcriptional regulator
HRD69_RS13795	ENOG4105YXP	it directly binds FlhC, thus inhibiting the binding of the FlhC FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus (By similarity)
HRD69_RS13800	ENOG4105MQ3	flagellar protein FliS
HRD69_RS13805	ENOG4105DTS	flagellar hook-associated
HRD69_RS13815	ENOG4108C80	FliB family
HRD69_RS13820	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRD69_RS13825	ENOG4108M9K	flagella biosynthesis protein FliZ
HRD69_RS13830	ENOG4105K6H	D-cysteine desulfhydrase
HRD69_RS13835	ENOG4105EAB	amino acid AbC transporter
HRD69_RS13840	ENOG4105E5Q	amino acid AbC transporter
HRD69_RS13845	ENOG4105CDA	abc transporter atp-binding protein
HRD69_RS13860	ENOG4105C26	Dehydrogenase
HRD69_RS13865	ENOG4105CK7	Sodium proline symporter
HRD69_RS13870	ENOG4105EKT	)-iron permease
HRD69_RS13875	ENOG410650H	(LipO)protein
HRD69_RS13890	ENOG4105CSH	Transporter
HRD69_RS13900	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HRD69_RS13915	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRD69_RS13930	ENOG4105E5K	Alpha-amylase
HRD69_RS13935	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS13945	ENOG4105RA2	Membrane
HRD69_RS13950	ENOG4105XVG	cytoplasmic protein
HRD69_RS13955	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD69_RS13960	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HRD69_RS13965	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HRD69_RS13985	ENOG4105ZTC	transcriptional activator, Ogr delta
HRD69_RS14025	ENOG4108C33	Resolvase
HRD69_RS14040	ENOG4105PTU	response to oxidative stress
HRD69_RS14165	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HRD69_RS14215	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRD69_RS14220	ENOG4108IQK	o-acetylhomoserine
HRD69_RS14225	ENOG4105ECR	NmrA family
HRD69_RS14230	ENOG4105KVH	Transcriptional regulator
HRD69_RS14240	ENOG4105VTN	Protein of unknown function (DUF1311)
HRD69_RS14245	ENOG4105XXV	Acid-resistance protein
HRD69_RS14260	ENOG4105BZ1	(ABC) transporter
HRD69_RS14265	ENOG4105D5Q	Arginine ornithine antiporter
HRD69_RS14280	ENOG4105N4N	Protein of unknown function (DUF2766)
HRD69_RS14285	ENOG4105TIK	
HRD69_RS14295	ENOG41064PC	
HRD69_RS14310	ENOG4105C85	amino acid
HRD69_RS14315	ENOG41079UR	PagP is required both for biosynthesis of hepta-acylated lipid A species containing palmitate and for resistance to cationic antimicrobial peptides (CAMPs). It catalyzes the transfer of a palmitate chain (16 0) from the sn-1 position of a glycerophospholipid to the free hydroxyl group of the (R)-3- hydroxymyristate chain at position 2 of lipid A (endotoxin) (By similarity)
HRD69_RS14330	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HRD69_RS14335	ENOG4105CJN	penicillin-binding protein
HRD69_RS14340	ENOG4105DHI	Methyltransferase
HRD69_RS14350	ENOG4105BZU	Histidine kinase
HRD69_RS14360	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
HRD69_RS14365	ENOG4108NK4	UPF0266 membrane protein
HRD69_RS14370	ENOG4105F3R	pts system mannose fructose sorbose family iid
HRD69_RS14375	ENOG4105ETZ	PTS System
HRD69_RS14380	ENOG4105DAS	pts system
HRD69_RS14385	ENOG4105EE5	Membrane protein terC
HRD69_RS14390	ENOG4105EJQ	L-serine dehydratase
HRD69_RS14395	ENOG4105P8F	nudix hydrolase
HRD69_RS14400	ENOG4105CRQ	synthase (Component I)
HRD69_RS14405	ENOG4105X5C	UPF0181 protein
HRD69_RS14410	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HRD69_RS14415	ENOG4105C1J	atp-dependent rna helicase
HRD69_RS14425	ENOG4105CUG	Oligopeptidase b
HRD69_RS14435	ENOG4105MPK	DNA polymerase III subunit theta
HRD69_RS14440	ENOG41090A1	ferritin
HRD69_RS14445	ENOG4105FXM	Copper resistance protein
HRD69_RS14450	ENOG4108PNC	copper resistance
HRD69_RS14455	ENOG4105NKT	exported protein
HRD69_RS14525	ENOG4105HRS	Antitermination protein
HRD69_RS14545	ENOG4108SHQ	Glutathione S-transferase
HRD69_RS14560	ENOG4105WT8	Protein of unknown function (DUF1480)
HRD69_RS14600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD69_RS14610	ENOG4105DY2	Paraquat-inducible protein b
HRD69_RS14615	ENOG4105H2K	paraquat-inducible protein a
HRD69_RS14620	ENOG4108ZGC	gaf domain protein
HRD69_RS14630	ENOG4105CN1	protease
HRD69_RS14635	ENOG4105D0M	Protease HtpX homolog
HRD69_RS14640	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HRD69_RS14645	ENOG4105CAZ	oligogalacturonide lyase
HRD69_RS14655	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD69_RS14660	ENOG4108ETY	sodium dicarboxylate symporter
HRD69_RS14665	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HRD69_RS14670	ENOG4108PU9	oligogalacturonate-specific porin
HRD69_RS14680	ENOG4108IJ9	(ABC) transporter
HRD69_RS14685	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HRD69_RS14690	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HRD69_RS14695	ENOG41061NF	Pectate lyase
HRD69_RS14700	ENOG4105CHR	reductase
HRD69_RS14705	ENOG4105M5J	Cupin 2, conserved barrel domain protein
HRD69_RS14710	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HRD69_RS14715	ENOG4107PN8	YfeABCD locus regulator
HRD69_RS14720	ENOG4105DEQ	transcriptional regulator
HRD69_RS14725	ENOG4105CYC	Transferase
HRD69_RS14730	ENOG4108M7F	enoyl-CoA hydratase isomerase
HRD69_RS14735	ENOG4105DJT	lAO AO transport system ATPase
HRD69_RS14740	ENOG4105D5P	Methylmalonyl-coA mutase
HRD69_RS14750	ENOG4105CC5	ABC transporter
HRD69_RS14755	ENOG4105CC5	ABC transporter
HRD69_RS14760	ENOG4105DIK	(ABC) transporter
HRD69_RS14765	ENOG4105DSE	periplasmic solute binding protein
HRD69_RS14770	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HRD69_RS14775	ENOG41082NP	Multiple antibiotic resistance
HRD69_RS14795	ENOG4108UQV	Membrane
HRD69_RS14800	ENOG41087WU	
HRD69_RS14810	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HRD69_RS14815	ENOG41082NX	50s ribosomal protein l35
HRD69_RS14840	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRD69_RS14845	ENOG4105ED1	spovr family
HRD69_RS14855	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HRD69_RS14860	ENOG4105DHQ	Histidine kinase
HRD69_RS14865	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HRD69_RS14870	ENOG4105H4F	exported protein
HRD69_RS14875	ENOG4105CNH	Multidrug resistance protein MdtL
HRD69_RS14880	ENOG4105BZU	Histidine kinase
HRD69_RS14885	ENOG4105EUB	pirin domain protein
HRD69_RS14890	ENOG4105HEI	LysR family (Transcriptional regulator
HRD69_RS14900	ENOG4106AKX	UPF0229 protein
HRD69_RS14905	ENOG4105CYN	Serine protein kinase
HRD69_RS14910	ENOG4105GNX	MltA-interacting MipA family protein
HRD69_RS14915	ENOG4105DSB	aldose 1-epimerase
HRD69_RS14940	ENOG4105VUT	cytoplasmic protein
HRD69_RS14945	ENOG4108RWI	nicotinamidase
HRD69_RS14950	ENOG4105HDK	L-asparaginase
HRD69_RS14955	ENOG4105D07	Signal peptide peptidase, SppA
HRD69_RS14960	ENOG41069NU	Nitroreductase
HRD69_RS14970	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD69_RS14975	ENOG4105MTM	Protein of unknown function (DUF1496)
HRD69_RS14980	ENOG4105M6F	mutator MutT protein
HRD69_RS14985	ENOG4105CGK	Exodeoxyribonuclease III
HRD69_RS14990	ENOG4105SKE	transcriptional Regulator LysR family
HRD69_RS15015	ENOG4105CIY	formyltetrahydrofolate deformylase
HRD69_RS15020	ENOG4105K5B	UPF0225 protein
HRD69_RS15025	ENOG4105I93	response regulator
HRD69_RS15030	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HRD69_RS15045	ENOG4105C0A	alcohol dehydrogenase
HRD69_RS15050	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HRD69_RS15055	ENOG4108J59	Extracellular solute-binding protein, family 5
HRD69_RS15060	ENOG4107QSI	ABC, transporter
HRD69_RS15065	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS15070	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRD69_RS15075	ENOG4105C3U	ABC transporter
HRD69_RS15080	ENOG4108JQ7	(ABC) transporter
HRD69_RS15090	ENOG4108W5H	UPF0263 protein
HRD69_RS15095	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HRD69_RS15105	ENOG4105CMB	EAL domain-containing protein
HRD69_RS15120	ENOG4105K9H	YciI-like protein
HRD69_RS15125	ENOG410822N	TonB family
HRD69_RS15130	ENOG4105NAU	thioesterase Superfamily protein
HRD69_RS15135	ENOG4107835	probably involved in intracellular septation (By similarity)
HRD69_RS15145	ENOG4108S3I	UPF0259 membrane protein
HRD69_RS15150	ENOG4105EIF	outer membrane protein W
HRD69_RS15160	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HRD69_RS15165	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HRD69_RS15170	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HRD69_RS15185	ENOG4105DB7	PHP domain protein
HRD69_RS15190	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HRD69_RS15200	ENOG4108Q9V	regulatoR
HRD69_RS15210	ENOG4108C33	Resolvase
HRD69_RS15245	ENOG4105FE9	pseudouridine synthase
HRD69_RS15250	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HRD69_RS15255	ENOG4105UBK	short-chain dehydrogenase reductase
HRD69_RS15260	ENOG4105ERU	peptidase
HRD69_RS15265	ENOG4105RKX	Protein of unknown function (DUF2498)
HRD69_RS15270	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRD69_RS15275	ENOG4107R11	Transcriptional regulator
HRD69_RS15285	ENOG4107QM5	aconitate hydratase
HRD69_RS15295	ENOG4105EYK	Phosphatidylglycerophosphatase B
HRD69_RS15300	ENOG4105Q4A	inner membrane protein yciS
HRD69_RS15305	ENOG4105CFV	Tetratricopeptide repeat protein
HRD69_RS15325	ENOG4108ZJT	translation initiation factor, Sui1
HRD69_RS15335	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
HRD69_RS15345	ENOG4105N2W	Transcriptional regulator
HRD69_RS15350	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HRD69_RS15355	ENOG4105VCD	cytoplasmic protein
HRD69_RS15360	ENOG4105D22	carbon starvation protein
HRD69_RS15365	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HRD69_RS15370	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HRD69_RS15375	ENOG4107TT5	NLP P60 protein
HRD69_RS15385	ENOG4105GQR	Chaperone
HRD69_RS15390	ENOG4105CW0	outer membrane usher protein
HRD69_RS15400	ENOG4105EQR	Transposase IS116 IS110 IS902
HRD69_RS15405	ENOG4105KVH	Transcriptional regulator
HRD69_RS15410	ENOG4105CB2	alcohol dehydrogenase
HRD69_RS15445	ENOG4105CSM	endonuclease III
HRD69_RS15455	ENOG4108UQQ	Electron transport complex
HRD69_RS15465	ENOG4105UEI	Transcriptional Regulator AraC Family
HRD69_RS15480	ENOG4105DGN	Electron transport complex
HRD69_RS15485	ENOG4105M9B	inner membrane protein ydgK
HRD69_RS15490	ENOG4105CKU	formyltetrahydrofolate synthetase
HRD69_RS15495	ENOG4108JJA	ABC, transporter
HRD69_RS15505	ENOG4108JJA	ABC, transporter
HRD69_RS15520	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
HRD69_RS15525	ENOG4105C2J	ABC transporter
HRD69_RS15530	ENOG4105CNN	ABC, transporter
HRD69_RS15540	ENOG4105D9R	oxidoreductase
HRD69_RS15545	ENOG4105DHU	Bile acid
HRD69_RS15550	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HRD69_RS15560	ENOG4105C87	Aminotransferase class I and II
HRD69_RS15565	ENOG4105CI1	PTS System
HRD69_RS15570	ENOG4107P2S	Transcriptional regulator
HRD69_RS15580	ENOG4106J39	exported protein
HRD69_RS15585	ENOG4105EIP	mannose-6-phosphate isomerase
HRD69_RS15590	ENOG4105C9Q	fumarate hydratase class II
HRD69_RS15605	ENOG4105D94	Major Facilitator Superfamily
HRD69_RS15610	ENOG4106NZI	LysR family Transcriptional regulator
HRD69_RS15615	ENOG4105DAG	ROK family
HRD69_RS15620	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HRD69_RS15630	ENOG4105KBG	Protein of unknown function (DUF1161)
HRD69_RS15635	ENOG4105M5Q	UPF0482 protein
HRD69_RS15640	ENOG4105KK4	UPF0060 membrane protein
HRD69_RS15650	ENOG4105EMU	Dehydrogenase
HRD69_RS15660	ENOG4105TDT	uncharacterized protein yahO
HRD69_RS15675	ENOG4105CYM	Glutathione S-transferase
HRD69_RS15685	ENOG4108JUA	Transcriptional regulator
HRD69_RS15690	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
HRD69_RS15695	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HRD69_RS15705	ENOG4108RYR	transcriptional regulator AsnC family
HRD69_RS15715	ENOG4105DSP	amino acid AbC transporter
HRD69_RS15720	ENOG4105E89	ABC transporter
HRD69_RS15725	ENOG4106V2I	dimethylaminohydrolase
HRD69_RS15755	ENOG4105FYV	Amp nucleosidase
HRD69_RS15780	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HRD69_RS15790	ENOG4105CVK	Glutamate decarboxylase
HRD69_RS15795	ENOG4105E5D	amino acid
HRD69_RS15805	ENOG4105PAD	Hydrolase
HRD69_RS15830	ENOG4108S5C	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity)
HRD69_RS15840	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HRD69_RS15845	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HRD69_RS15850	ENOG4105Q9Y	Universal stress protein
HRD69_RS15855	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HRD69_RS15860	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HRD69_RS15865	ENOG4105C5D	exported protein
HRD69_RS15870	ENOG4105D5Q	Arginine ornithine antiporter
HRD69_RS15880	ENOG4107EXC	regulatoR
HRD69_RS15885	ENOG4105JJR	Histidine kinase
HRD69_RS15890	ENOG4105CTD	carboxy-peptidase
HRD69_RS15900	ENOG4105CVW	peptidase s1 and s6 chymotrypsin hap
HRD69_RS15915	ENOG4105CQ7	ATP-dependent helicase
HRD69_RS15920	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HRD69_RS15945	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS15950	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
HRD69_RS15955	ENOG4105WXT	Conserved Protein
HRD69_RS15960	ENOG410689M	(LipO)protein
HRD69_RS15965	ENOG4107H52	Dicarboxylate transport
HRD69_RS15970	ENOG4105C5I	Dehydrogenase
HRD69_RS15975	ENOG4105IKK	cytoplasmic protein
HRD69_RS15980	ENOG4105KT7	mgtC SapB transporter
HRD69_RS15990	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HRD69_RS16000	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HRD69_RS16015	ENOG4107QSI	ABC, transporter
HRD69_RS16020	ENOG4105KXI	murein peptide amidase A
HRD69_RS16025	ENOG4107S8C	mandelate racemase muconate lactonizing
HRD69_RS16030	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HRD69_RS16050	ENOG4106K28	UPF0283 membrane protein
HRD69_RS16055	ENOG4105CM6	amino acid regulated cytosolic protein
HRD69_RS16065	ENOG4105FM1	phage shock protein C
HRD69_RS16070	ENOG4105YYT	phage shock protein B
HRD69_RS16075	ENOG41087YS	Phage shock protein A
HRD69_RS16080	ENOG4105E51	psp operon transcriptional activator
HRD69_RS16085	ENOG4108J59	Extracellular solute-binding protein, family 5
HRD69_RS16090	ENOG4108I5W	peptide transport system, permease protein
HRD69_RS16095	ENOG4108EU3	peptide transport system, permease
HRD69_RS16100	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HRD69_RS16105	ENOG4108JQ2	peptide transport system atp-binding protein
HRD69_RS16110	ENOG4105Q4T	oxidoreductase
HRD69_RS16115	ENOG4105DUX	Transporter
HRD69_RS16125	ENOG41069YE	inner membrane protein yohC
HRD69_RS16130	ENOG4108ZR5	Conserved Protein
HRD69_RS16135	ENOG4108K3A	Glutathione S-transferase
HRD69_RS16145	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HRD69_RS16155	ENOG410642K	Lysozyme inhibitor
HRD69_RS16160	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HRD69_RS16165	ENOG4108XTF	Outer Membrane Lipoprotein
HRD69_RS16170	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
HRD69_RS16180	ENOG4105Y49	secretion protein, HlyD family
HRD69_RS16185	ENOG4105DSW	Fusaric acid resistance protein
HRD69_RS16190	ENOG4107RGM	aldo keto reductase
HRD69_RS16195	ENOG4105XZD	Fe-S protein
HRD69_RS16200	ENOG4105DIJ	Phosphoethanolamine transferase
HRD69_RS16205	ENOG4108WUH	Transcriptional regulator, TetR family
HRD69_RS16210	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRD69_RS16215	ENOG4108UYE	Lactoylglutathione lyase
HRD69_RS16220	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HRD69_RS16225	ENOG4105M2J	Glutaredoxin
HRD69_RS16230	ENOG4105K4H	Nlp p60 protein
HRD69_RS16235	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRD69_RS16245	ENOG4105ETE	Transcriptional regulator (LacI family
HRD69_RS16250	ENOG4105F52	Transcriptional regulator
HRD69_RS16255	ENOG4105CZQ	inner membrane transport protein YdhC
HRD69_RS16260	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HRD69_RS16265	ENOG4108R6K	riboflavin synthase, subunit alpha
HRD69_RS16270	ENOG4107QI1	Mate efflux family protein
HRD69_RS16285	ENOG4105CA9	Pyruvate kinase
HRD69_RS16295	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HRD69_RS16300	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRD69_RS16310	ENOG4105JRK	feS assembly protein SufD
HRD69_RS16315	ENOG4105C3K	feS assembly ATPase SufC
HRD69_RS16320	ENOG4105DIW	FeS assembly protein SUFB
HRD69_RS16325	ENOG4108Z4V	iron-sulfur cluster assembly
HRD69_RS16330	ENOG4105KA0	thioesterase Superfamily protein
HRD69_RS16335	ENOG4105CQB	FAD linked oxidase domain protein
HRD69_RS16340	ENOG4105IPI	Membrane
HRD69_RS16350	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HRD69_RS16355	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HRD69_RS16360	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRD69_RS16365	ENOG4107F3C	Hemin uptake protein
HRD69_RS16370	ENOG4107ENK	receptor
HRD69_RS16380	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HRD69_RS16385	ENOG4108QBX	(LipO)protein
HRD69_RS16390	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HRD69_RS16395	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
HRD69_RS16400	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD69_RS16405	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HRD69_RS16415	ENOG4105CKK	Glycosyl transferase, family 2
HRD69_RS16420	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRD69_RS16425	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS16430	ENOG4108V06	Glutathione peroxidase
HRD69_RS16435	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HRD69_RS16440	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
HRD69_RS16445	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRD69_RS16450	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HRD69_RS16455	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRD69_RS16465	ENOG4108ZZ3	UPF0260 protein
HRD69_RS16470	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HRD69_RS16480	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HRD69_RS16485	ENOG4107QMS	site-determining protein
HRD69_RS16490	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HRD69_RS16495	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HRD69_RS16500	ENOG4105CEY	Amp-dependent synthetase and ligase
HRD69_RS16505	ENOG4105Y4Z	Outer Membrane Lipoprotein
HRD69_RS16510	ENOG41072GX	Peptidase M22 Glycoprotease
HRD69_RS16515	ENOG4105DVT	helicase
HRD69_RS16520	ENOG4105M4H	endoribonuclease L-psp
HRD69_RS16530	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HRD69_RS16535	ENOG4108M1A	Chitin-binding protein
HRD69_RS16540	ENOG4108UHU	Aldolase
HRD69_RS16545	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HRD69_RS16550	ENOG4106KNT	transcriptional regulator
HRD69_RS16555	ENOG4105CA9	Pyruvate kinase
HRD69_RS16560	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HRD69_RS16565	ENOG4105DR5	peptidase
HRD69_RS16570	ENOG4105NXV	High-affinity zinc uptake system protein
HRD69_RS16575	ENOG4105FDK	ABC transporter
HRD69_RS16580	ENOG4105FAV	ABC, transporter
HRD69_RS16585	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HRD69_RS16590	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HRD69_RS16600	ENOG4105CDY	transcriptional regulatory protein
HRD69_RS16605	ENOG4108TIT	dATP pyrophosphohydrolase
HRD69_RS16610	ENOG4105C9M	aspartyl-trna synthetase
HRD69_RS16615	ENOG4105D3W	isochorismatase
HRD69_RS16620	ENOG41081XQ	Conserved Protein
HRD69_RS16625	ENOG4105WJG	Glutathione
HRD69_RS16645	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HRD69_RS16650	ENOG4106N3A	copper homeostasis protein cutc
HRD69_RS16655	ENOG4106ZCM	YecM protein
HRD69_RS16660	ENOG4105C75	arginyL-tRNA synthetase
HRD69_RS16665	ENOG4105CJR	Integral membrane protein (MviN
HRD69_RS16670	ENOG4105EP9	oxidoreductase
HRD69_RS16680	ENOG4105D9U	N-acetyltransferase
HRD69_RS16685	ENOG4105EV4	Multidrug resistance protein mdtH
HRD69_RS16690	ENOG4105F3T	(LipO)protein
HRD69_RS16695	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
HRD69_RS16705	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HRD69_RS16720	ENOG4105BZU	Histidine kinase
HRD69_RS16725	ENOG4105CHH	sulfate transporter
HRD69_RS16730	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HRD69_RS16735	ENOG41063JG	Transcriptional regulator
HRD69_RS16740	ENOG4108YY7	Invasion gene expression up-regulator SirB
HRD69_RS16745	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HRD69_RS16755	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HRD69_RS16760	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HRD69_RS16770	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HRD69_RS16775	ENOG4105MGX	transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria
HRD69_RS16780	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HRD69_RS16790	ENOG4105C3G	gtp-binding protein
HRD69_RS16795	ENOG4105ENX	hydrolase
HRD69_RS16830	ENOG4108K5P	(LipO)protein
HRD69_RS16840	ENOG4108MEK	Metal-binding protein YodA
HRD69_RS16845	ENOG4108HWV	)-transporter
HRD69_RS16850	ENOG4105C2J	ABC transporter
HRD69_RS16870	ENOG4105CZE	histidine utilization repressor
HRD69_RS16875	ENOG4105CI2	imidazolone-5-propionate hydrolase
HRD69_RS16890	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
HRD69_RS16895	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HRD69_RS16905	ENOG4105F4X	arginine
HRD69_RS16910	ENOG4105C8Y	Acetylornithine aminotransferase
HRD69_RS16915	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HRD69_RS16920	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HRD69_RS16925	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HRD69_RS16935	ENOG4105BZU	Histidine kinase
HRD69_RS16940	ENOG4107R11	Transcriptional regulator
HRD69_RS16950	ENOG4105EWV	Sodium calcium exchanger membrane region
HRD69_RS16955	ENOG4105D5M	phosphate starvation-inducible protein
HRD69_RS16970	ENOG4105CND	Glycosyl transferase, family 2
HRD69_RS16975	ENOG4107BJW	polysaccharide deacetylase
HRD69_RS16980	ENOG4108TUY	outer membrane protein PgaA
HRD69_RS17005	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD69_RS17015	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HRD69_RS17030	ENOG4107SJW	iron permease, FTR1
HRD69_RS17040	ENOG4105VCP	PTS System
HRD69_RS17045	ENOG4105CS2	ec 3.2.1.21
HRD69_RS17050	ENOG4105CK1	PTS System
HRD69_RS17055	ENOG4105VZJ	PTS System
HRD69_RS17060	ENOG4105DDV	Transcriptional regulator (LacI family
HRD69_RS17075	ENOG4105CSV	Glutaminase
HRD69_RS17080	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HRD69_RS17085	ENOG4108MRH	transcriptional regulatory protein
HRD69_RS17095	ENOG4105C85	amino acid
HRD69_RS17105	ENOG4106UW1	Major Facilitator superfamily
HRD69_RS17110	ENOG4108HCJ	Hydrolase
HRD69_RS17135	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HRD69_RS17140	ENOG4108R99	pseudouridine synthase
HRD69_RS17150	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HRD69_RS17155	ENOG41075W9	High frequency lysogenization protein HflD homolog
HRD69_RS17160	ENOG4107QTF	adenylosuccinate lyase
HRD69_RS17165	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HRD69_RS17175	ENOG4105EZE	Cupin 4 family protein
HRD69_RS17190	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
HRD69_RS17195	ENOG4105D60	lipoprotein releasing system transmembrane protein
HRD69_RS17205	ENOG4105D60	lipoprotein releasing system transmembrane protein
HRD69_RS17210	ENOG4108JA2	transcriptioN-repair coupling factor
HRD69_RS17215	ENOG4107MBR	17 kDa surface antigen
HRD69_RS17220	ENOG4105CEP	NADH dehydrogenase
HRD69_RS17225	ENOG4105D0Y	UPF0227 protein
HRD69_RS17235	ENOG4108RUM	thiamine kinase
HRD69_RS17240	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
HRD69_RS17245	ENOG41090DQ	Lipoprotein
HRD69_RS17250	ENOG4105K59	histidine triad (HIT) protein
HRD69_RS17255	ENOG4105F9E	Shikimate 5-dehydrogenase
HRD69_RS17270	ENOG4105C4X	radical SAM domain protein
HRD69_RS17275	ENOG4108MBX	Secretion Protein
HRD69_RS17280	ENOG4108JJA	ABC, transporter
HRD69_RS17295	ENOG4105MZU	cell filamentation protein
HRD69_RS17300	ENOG4105CI1	PTS System
HRD69_RS17305	ENOG4105F8V	Hydrolase, tatD family
HRD69_RS17310	ENOG4107QRG	dna polymerase iii
HRD69_RS17315	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HRD69_RS17320	ENOG4105HHA	aminodeoxychorismate lyase
HRD69_RS17325	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HRD69_RS17330	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD69_RS17340	ENOG4105CHR	reductase
HRD69_RS17345	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HRD69_RS17355	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HRD69_RS17360	ENOG4105VGS	50s ribosomal protein l32
HRD69_RS17365	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HRD69_RS17370	ENOG4108UHJ	MAF-like protein
HRD69_RS17375	ENOG4105EI2	Pseudouridine synthase
HRD69_RS17380	ENOG4107QQB	Ribonuclease E
HRD69_RS17380	ENOG4107QQB	Ribonuclease E
HRD69_RS17385	ENOG41067V3	Antibiotic biosynthesis monooxygenase
HRD69_RS17390	ENOG4105EKE	dihydroorotase
HRD69_RS17400	ENOG4105PVA	Biofilm formation regulatory protein BssS
HRD69_RS17420	ENOG4105DSF	transport protein
HRD69_RS17435	ENOG4105D1S	lipid A biosynthesis
HRD69_RS17440	ENOG4105MGM	doxx family
HRD69_RS17445	ENOG4105C6X	Major Facilitator
HRD69_RS17450	ENOG4105DUX	Transporter
HRD69_RS17460	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HRD69_RS17465	ENOG4105DJ9	glucan biosynthesis protein
HRD69_RS17480	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HRD69_RS17490	ENOG4107YC3	synthase
HRD69_RS17495	ENOG4105VJY	transcriptional regulator
HRD69_RS17510	ENOG4107QX9	Thiol disulfide interChange protein
HRD69_RS17515	ENOG4105DA4	cytochrome c-type biogenesis protein
HRD69_RS17520	ENOG4105DVI	reductase, NrfD
HRD69_RS17525	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HRD69_RS17530	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
HRD69_RS17535	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HRD69_RS17540	ENOG4105Q26	Siderophore-interacting protein
HRD69_RS17560	ENOG4105DUU	IucA IucC family protein
HRD69_RS17565	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HRD69_RS17585	ENOG4105M5Q	UPF0482 protein
HRD69_RS17695	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD69_RS17735	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HRD69_RS17740	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HRD69_RS17750	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
HRD69_RS17755	ENOG4105K4P	CoA-binding domain protein
HRD69_RS17765	ENOG4108Z5K	methylglyoxal synthase
HRD69_RS17770	ENOG41088T4	Helicase IV
HRD69_RS17775	ENOG410901E	Membrane
HRD69_RS17780	ENOG4105EM2	membrane
HRD69_RS17785	ENOG4108RZ1	DNA transformation protein
HRD69_RS17790	ENOG4108ZD2	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division (By similarity)
HRD69_RS17800	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HRD69_RS17805	ENOG4105DAN	ATP-dependent protease
HRD69_RS17810	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HRD69_RS17820	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRD69_RS17825	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HRD69_RS17830	ENOG4108Q2G	(LipO)protein
HRD69_RS17835	ENOG4105DY2	Paraquat-inducible protein b
HRD69_RS17840	ENOG4105F1S	paraquat-inducible protein a
HRD69_RS17845	ENOG4105C5H	ABC transporter
HRD69_RS17850	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HRD69_RS17855	ENOG4105QVC	MOSC domain-containing protein
HRD69_RS17860	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HRD69_RS17865	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HRD69_RS17870	ENOG4105CD8	aminopeptidase N
HRD69_RS17875	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HRD69_RS17880	ENOG4105C5S	asparaginyl-tRNA synthetase
HRD69_RS17890	ENOG4105CGF	Aromatic amino acid aminotransferase
HRD69_RS17895	ENOG4105BZU	Histidine kinase
HRD69_RS17900	ENOG4105C5X	domain protein
HRD69_RS17905	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HRD69_RS17910	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HRD69_RS17925	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HRD69_RS17930	ENOG4106371	Methyltransferase
HRD69_RS17935	ENOG4107S90	membrAne
HRD69_RS17940	ENOG4107VR7	transferase activity, transferring phosphorus-containing groups
HRD69_RS17950	ENOG4105W49	UPF0434 protein
HRD69_RS17955	ENOG4105VEQ	Cold shock protein
HRD69_RS17960	ENOG4105E32	cytoplasmic protein
HRD69_RS17965	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HRD69_RS17975	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HRD69_RS17980	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRD69_RS17985	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HRD69_RS17990	ENOG4105CAT	Cytidine monophosphate kinase
HRD69_RS17995	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HRD69_RS18005	ENOG4105HDK	L-asparaginase
HRD69_RS18010	ENOG4105DDY	UPF0142 protein ycaO
HRD69_RS18015	ENOG4105TMB	Formate nitrite transporter
HRD69_RS18020	ENOG4105C6N	Formate acetyltransferase
HRD69_RS18025	ENOG4105F1A	Pyruvate formate-lyase
HRD69_RS18030	ENOG4108ISG	Major Facilitator
HRD69_RS18035	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HRD69_RS18040	ENOG4105D1H	recombination factor protein RarA
HRD69_RS18045	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HRD69_RS18050	ENOG4105CNU	cell division protein FtsK
HRD69_RS18055	ENOG4105EW9	transcriptional regulator AsnC family
HRD69_RS18060	ENOG4105C3M	thioredoxin reductase
HRD69_RS18065	ENOG4108JJ9	ABC, transporter
HRD69_RS18070	ENOG4108JJ8	(ABC) transporter
HRD69_RS18075	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HRD69_RS18085	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD69_RS18090	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HRD69_RS18095	ENOG4105VEQ	Cold shock protein
HRD69_RS18105	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD69_RS18110	ENOG4108MJ5	VirK protein
HRD69_RS18115	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HRD69_RS18120	ENOG4105DWU	Membrane
HRD69_RS18125	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HRD69_RS18130	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HRD69_RS18135	ENOG4105C7K	acetolactate synthase
HRD69_RS18140	ENOG4105JQZ	Methyltransferase
HRD69_RS18145	ENOG4105C5W	Aldolase
HRD69_RS18150	ENOG4105CGD	Nad-dependent epimerase dehydratase
HRD69_RS18155	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
HRD69_RS18160	ENOG41064MM	(LipO)protein
HRD69_RS18165	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
HRD69_RS18170	ENOG4105E5Z	arginine transporter ATP-binding subunit
HRD69_RS18175	ENOG4106PMH	Extracellular solute-binding protein family 3
HRD69_RS18180	ENOG4105GBT	ABC transporter
HRD69_RS18185	ENOG4105DMR	ABC, transporter
HRD69_RS18190	ENOG4106TNF	Periplasmic binding protein
HRD69_RS18200	ENOG4105RBQ	inner membrane protein ybjO
HRD69_RS18205	ENOG4105D38	putrescine abc transporter
HRD69_RS18210	ENOG4105F38	ABC transporter, permease
HRD69_RS18215	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS18220	ENOG4107RUE	extracellular solute-binding protein family 1
HRD69_RS18225	ENOG4108RMJ	sensory transduction regulator
HRD69_RS18230	ENOG4105X20	member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress
HRD69_RS18235	ENOG41090BQ	Glutaredoxin
HRD69_RS18240	ENOG4105D0C	transport protein
HRD69_RS18250	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HRD69_RS18255	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HRD69_RS18260	ENOG4107FB0	transcriptional regulator DeoR family
HRD69_RS18265	ENOG4105C44	Serine transporter
HRD69_RS18270	ENOG4105EJQ	L-serine dehydratase
HRD69_RS18275	ENOG4105DZ1	carboxypeptidase
HRD69_RS18285	ENOG4105C28	cystathionine
HRD69_RS18295	ENOG4108UMI	ABC transporter, permease
HRD69_RS18305	ENOG4105D01	(LipO)protein
HRD69_RS18320	ENOG4108TGY	Glutathione S-transferase
HRD69_RS18325	ENOG4105D05	Receptor
HRD69_RS18330	ENOG4108IQI	permease
HRD69_RS18335	ENOG4105DUM	transcriptional regulator, lysR family
HRD69_RS18345	ENOG4105HMI	Membrane
HRD69_RS18350	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HRD69_RS18355	ENOG4105DM4	PTS System
HRD69_RS18360	ENOG4105DE4	1-phosphofructokinase
HRD69_RS18365	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HRD69_RS18370	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HRD69_RS18375	ENOG4105CUW	cytochrome C-TYPE protein
HRD69_RS18380	ENOG4107QY8	reductase
HRD69_RS18385	ENOG4105KRS	Proteinase inhibitor
HRD69_RS18395	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRD69_RS18405	ENOG4105DEI	Mannitol dehydrogenase
HRD69_RS18410	ENOG4107YCY	Transcriptional regulator
HRD69_RS18415	ENOG4105CKI	cobalamin synthesis protein
HRD69_RS18420	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HRD69_RS18425	ENOG4107TT5	NLP P60 protein
HRD69_RS18430	ENOG4105CXC	rtn protein
HRD69_RS18435	ENOG4105E43	Extracellular solute-binding protein, family 5
HRD69_RS18440	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HRD69_RS18445	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HRD69_RS18450	ENOG4108JQ5	ABC transporter
HRD69_RS18455	ENOG4105HG6	
HRD69_RS18460	ENOG4105C2C	drug resistance transporter, Bcr CflA
HRD69_RS18465	ENOG4105I08	Pseudouridine synthase
HRD69_RS18470	ENOG4105CFI	type iii restriction protein res subunit
HRD69_RS18480	ENOG4106V8H	Nucleoid-associated protein
HRD69_RS18485	ENOG4105PAN	UPF0352 protein
HRD69_RS18490	ENOG4105E68	Sulfatase
HRD69_RS18540	ENOG4105SFK	cell wall hydrolase autolysin
HRD69_RS18545	ENOG4108YYQ	gCN5-related N-acetyltransferase
HRD69_RS18550	ENOG4105HVQ	Regulatory factor of maltose metabolism
HRD69_RS18565	ENOG4105CS2	ec 3.2.1.21
HRD69_RS18570	ENOG4105C5Y	PTS System
HRD69_RS18575	ENOG4108Q3X	Transcriptional regulator
HRD69_RS18590	ENOG4108T86	baseplate J family protein
HRD69_RS18630	ENOG4105TKZ	Tail Sheath
HRD69_RS18645	ENOG4105KUS	lysozyme
HRD69_RS18655	ENOG4105HRS	Antitermination protein
HRD69_RS18665	ENOG4105Y50	Virulence Protein
HRD69_RS18670	ENOG4105C8Q	Methyl-accepting chemotaxis
HRD69_RS18680	ENOG4105CT4	transporter
HRD69_RS18695	ENOG4107R6D	beta-lactam binding protein AmpH
HRD69_RS18700	ENOG4108BY2	phosphohistidine phosphatase
HRD69_RS18705	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HRD69_RS18710	ENOG4105CHU	acetyl-coa acetyltransferase
HRD69_RS18715	ENOG4105KZW	UPF0381 protein
HRD69_RS18720	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HRD69_RS18735	ENOG410903C	(LipO)protein
HRD69_RS18740	ENOG4105KWW	Biogenesis protein
HRD69_RS18745	ENOG4105KWW	Biogenesis protein
HRD69_RS18750	ENOG4107QX9	Thiol disulfide interChange protein
HRD69_RS18755	ENOG4105DA4	cytochrome c-type biogenesis protein
HRD69_RS18760	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HRD69_RS18765	ENOG4105X3C	heme exporter protein
HRD69_RS18770	ENOG41060IM	Heme exporter protein
HRD69_RS18775	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HRD69_RS18785	ENOG4105S64	Formate nitrite transporter
HRD69_RS18815	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HRD69_RS18825	ENOG4105NTW	Transcriptional regulator
HRD69_RS18835	ENOG4105CS2	ec 3.2.1.21
HRD69_RS18840	ENOG4105C5Y	PTS System
HRD69_RS18845	ENOG4105DDV	Transcriptional regulator (LacI family
HRD69_RS18850	ENOG4108YYC	ycei family
HRD69_RS18855	ENOG4105DS1	cytochrome b561
HRD69_RS18870	ENOG4105DHJ	ABC, transporter
HRD69_RS18900	ENOG4105CUB	amino acid
HRD69_RS18905	ENOG4105CVE	Lytic murein transglycosylase
HRD69_RS18920	ENOG4105D5K	Hemolysin activator protein
HRD69_RS18935	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS18945	ENOG4107QY8	reductase
HRD69_RS18950	ENOG4105QAX	Iron-sulfur
HRD69_RS18955	ENOG4107KGK	dmso reductase anchor subunit
HRD69_RS18970	ENOG4107Y60	(LipO)protein
HRD69_RS18980	ENOG4106B0W	Curli production assembly transport component CsgG
HRD69_RS18985	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
HRD69_RS18995	ENOG4108VKM	cytochrome b561
HRD69_RS19000	ENOG4105CHM	Aminotransferase
HRD69_RS19010	ENOG41072TH	Protein of unknown function (DUF1479)
HRD69_RS19015	ENOG4108HRK	Histidine kinase
HRD69_RS19020	ENOG4105DY9	regulatoR
HRD69_RS19025	ENOG4105FCD	Major Facilitator
HRD69_RS19030	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HRD69_RS19040	ENOG4105C5Q	Transcriptional regulator
HRD69_RS19045	ENOG4107RA9	decarboxylase
HRD69_RS19050	ENOG4105CPC	Aldo Keto reductase
HRD69_RS19060	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HRD69_RS19065	ENOG4105D9N	nucleoside
HRD69_RS19100	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HRD69_RS19125	ENOG4105VRT	cytoplasmic protein
HRD69_RS19130	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HRD69_RS19145	ENOG4105C6T	cysteine synthase
HRD69_RS19155	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HRD69_RS19160	ENOG4105C5Y	PTS System
HRD69_RS19165	ENOG4105E0F	Histidine kinase
HRD69_RS19170	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD69_RS19175	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HRD69_RS19185	ENOG41090SZ	ABC-2 type transporter
HRD69_RS19205	ENOG41084CK	capsule polysaccharide
HRD69_RS19210	ENOG4105E12	capsule polysaccharide
HRD69_RS19215	ENOG4107V1M	polysaccharide export protein
HRD69_RS19220	ENOG4105ECX	polysaccharide export
HRD69_RS19225	ENOG4105C6T	cysteine synthase
HRD69_RS19235	ENOG4105ECW	sulfate abc transporter
HRD69_RS19240	ENOG4108I5D	sulfate abc transporter
HRD69_RS19245	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HRD69_RS19260	ENOG4105QEK	Transcriptional regulator
HRD69_RS19265	ENOG4108R66	Conserved Protein
HRD69_RS19285	ENOG4105EZR	dyp-type peroxidase family protein
HRD69_RS19290	ENOG4105E7K	(LipO)protein
HRD69_RS19295	ENOG4105H4F	exported protein
HRD69_RS19305	ENOG4108R6G	acetyltransferase
HRD69_RS19310	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HRD69_RS19315	ENOG4108UPT	UPF0178 protein
HRD69_RS19320	ENOG4105C6K	Malic enzyme
HRD69_RS19330	ENOG4105CUW	cytochrome C-TYPE protein
HRD69_RS19335	ENOG4108ZMS	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
HRD69_RS19340	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HRD69_RS19345	ENOG41061Q0	Assembly protein for periplasmic nitrate reductase
HRD69_RS19350	ENOG4108ZNS	ferredoxin-type protein NapF
HRD69_RS19355	ENOG4105WH1	Two component transcriptional regulator luxr family
HRD69_RS19365	ENOG4105BZS	acriflavin resistance protein
HRD69_RS19370	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRD69_RS19375	ENOG4107Z33	ABC transporter, permease
HRD69_RS19390	ENOG4105KUZ	arsenate reductase
HRD69_RS19395	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HRD69_RS19405	ENOG4105XYK	UPF0370 protein
HRD69_RS19410	ENOG4106KED	esterase YpfH
HRD69_RS19415	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HRD69_RS19420	ENOG4108VMM	UPF0756 membrane protein
HRD69_RS19425	ENOG4105CGZ	zinc metallopeptidase
HRD69_RS19430	ENOG4105C8V	SAICAR synthetase
HRD69_RS19435	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD69_RS19440	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HRD69_RS19445	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HRD69_RS19450	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRD69_RS19455	ENOG4105C02	permease
HRD69_RS19460	ENOG4105ERG	peptidase m48, ste24p
HRD69_RS19465	ENOG4105K89	arsenate reductase
HRD69_RS19470	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HRD69_RS19475	ENOG4105C2W	permease
HRD69_RS19480	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HRD69_RS19490	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HRD69_RS19495	ENOG4108MK9	spermidine N(1)-acetyltransferase
HRD69_RS19505	ENOG4105E2Z	phosphate ABC transporter (Permease
HRD69_RS19510	ENOG4105C8U	phosphate abc transporter
HRD69_RS19515	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HRD69_RS19520	ENOG4105C9X	ppx gppa phosphatase
HRD69_RS19530	ENOG4105CJW	magnesium transporter
HRD69_RS19535	ENOG4105BZU	Histidine kinase
HRD69_RS19540	ENOG4105R8A	Heat shock protein
HRD69_RS19550	ENOG4108VCD	Chaperone
HRD69_RS19555	ENOG4105CW0	outer membrane usher protein
HRD69_RS19575	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRD69_RS19585	ENOG4105BZS	acriflavin resistance protein
HRD69_RS19590	ENOG4105EB3	Histidine kinase
HRD69_RS19595	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRD69_RS19600	ENOG4105KWI	UPF0339 protein
HRD69_RS19615	ENOG4105CFP	Peptidase U32
HRD69_RS19620	ENOG4107TE5	Lipid kinase
HRD69_RS19625	ENOG410787A	Pts system, glucitol sorbitol-specific
HRD69_RS19630	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HRD69_RS19635	ENOG4105VI0	Pts system, glucitol sorbitol-specific
HRD69_RS19640	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
HRD69_RS19645	ENOG4105J92	DNA-binding transcriptional activator GutM
HRD69_RS19650	ENOG410804X	Transcriptional regulator
HRD69_RS19660	ENOG4108ZGU	inhibitor of vertebrate lysozyme
HRD69_RS19670	ENOG4105DWF	phosphomethylpyrimidine kinase
HRD69_RS19705	ENOG4108JJ7	ABC transporter
HRD69_RS19710	ENOG4105EZE	Cupin 4 family protein
HRD69_RS19780	ENOG4105CW0	outer membrane usher protein
HRD69_RS19785	ENOG4108VEV	chaperone
HRD69_RS19795	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRD69_RS19830	ENOG4105CDV	Ompa motb domain protein
HRD69_RS19845	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HRD69_RS19850	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HRD69_RS19855	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HRD69_RS19860	ENOG4105VPD	cellular component movement
HRD69_RS19870	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HRD69_RS19875	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD69_RS19880	ENOG4105N21	Membrane
HRD69_RS19895	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HRD69_RS19920	ENOG4108JQB	penicillin-binding protein 1C
HRD69_RS19925	ENOG4105DN3	alpha-2-macroglobulin domain protein
HRD69_RS19935	ENOG4108MGN	ATP-binding component of a transport system
HRD69_RS19940	ENOG4105YYA	enhanced serine sensitivity protein SseB
HRD69_RS19950	ENOG4105WVQ	Fe-S assembly protein IscX
HRD69_RS19955	ENOG4108ZIT	Ferredoxin, 2FE-2S
HRD69_RS19960	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HRD69_RS19975	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HRD69_RS19980	ENOG4105C3J	Cysteine desulfurase
HRD69_RS19985	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HRD69_RS19990	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HRD69_RS19995	ENOG4105ECY	inositol monophosphatase
HRD69_RS20000	ENOG4105D7X	high-affinity nickel-transporter
HRD69_RS20005	ENOG41065CD	Exported protein
HRD69_RS20010	ENOG4108MN2	Stationary phase inducible protein CsiE
HRD69_RS20015	ENOG4105D8G	Major Facilitator superfamily
HRD69_RS20025	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HRD69_RS20030	ENOG4108M21	
HRD69_RS20035	ENOG4105RMW	regulation of transcription, DNA-dependent
HRD69_RS20040	ENOG4108626	Racemase
HRD69_RS20045	ENOG41080QX	K07048 phosphotriesterase-related protein
HRD69_RS20050	ENOG4105MUZ	Protein of unknown function DUF2620
HRD69_RS20055	ENOG4106M0N	transport system permease protein
HRD69_RS20060	ENOG4108YZA	Nitrogen regulatory protein pii
HRD69_RS20065	ENOG4105C4K	Nad synthetase
HRD69_RS20070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRD69_RS20075	ENOG4108SKK	alpha helix protein
HRD69_RS20080	ENOG4107WP9	Histidine kinase
HRD69_RS20095	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HRD69_RS20100	ENOG4108Z6B	deaminase
HRD69_RS20110	ENOG4105HYY	HAD superfamily (Subfamily IF) hydrolase, YfhB
HRD69_RS20125	ENOG4106G6Q	Transcriptional regulator
HRD69_RS20130	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HRD69_RS20135	ENOG4107EFN	gluconate transport system permease 3
HRD69_RS20140	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HRD69_RS20145	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HRD69_RS20150	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HRD69_RS20155	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HRD69_RS20165	ENOG4105C3F	Signal peptidase i
HRD69_RS20170	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HRD69_RS20180	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HRD69_RS20190	ENOG41069PW	sigma-e factor negative regulatory protein
HRD69_RS20200	ENOG4108IYU	L-aspartate oxidase
HRD69_RS20205	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HRD69_RS20210	ENOG4105C1J	atp-dependent rna helicase
HRD69_RS20215	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HRD69_RS20220	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HRD69_RS20225	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HRD69_RS20230	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HRD69_RS20235	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HRD69_RS20240	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRD69_RS20250	ENOG4108Z1B	Cyclase dehydrase
HRD69_RS20255	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HRD69_RS20265	ENOG4105DFP	Integrase
HRD69_RS20275	ENOG410679B	prophage CP4-57 regulatory protein alpA
HRD69_RS20285	ENOG4105JXR	Protein of unknown function (DUF3296)
HRD69_RS20300	ENOG4105C4R	Atp-dependent dna helicase
HRD69_RS20330	ENOG4108MXD	gtp-binding protein
HRD69_RS20335	ENOG4108KZE	transcriptional regulator
HRD69_RS20345	ENOG4106J9S	Prophage
HRD69_RS20350	ENOG4105MFG	Antirestriction protein
HRD69_RS20355	ENOG4108XS9	dna repair protein
HRD69_RS20375	ENOG4108X3P	Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures
HRD69_RS20380	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
HRD69_RS20400	ENOG4105D5Q	Arginine ornithine antiporter
HRD69_RS20405	ENOG410901P	UPF0249 protein
HRD69_RS20410	ENOG4105EZV	Transcriptional regulator
HRD69_RS20415	ENOG4105VCP	PTS System
HRD69_RS20420	ENOG4105CS2	ec 3.2.1.21
HRD69_RS20425	ENOG4105CK1	PTS System
HRD69_RS20430	ENOG4105VZJ	PTS System
HRD69_RS20435	ENOG4108TGY	Glutathione S-transferase
HRD69_RS20450	ENOG4107SVH	Potassium channel protein
HRD69_RS20455	ENOG4105XXV	Acid-resistance protein
HRD69_RS20475	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)