locus-tag	class	description
M481_RS00490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M481_RS00520	COG1047	Peptidyl-prolyl cis-trans
M481_RS00615	COG0477	Major facilitator Superfamily
M481_RS00750	COG0849	cell division
M481_RS00820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M481_RS00900	COG1022	Amp-dependent synthetase and ligase
M481_RS01205	COG0849	cell division
M481_RS01210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M481_RS01230	COG0772	Belongs to the SEDS family
M481_RS01245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M481_RS01250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M481_RS01255	COG0768	penicillin binding
M481_RS01260	COG3116	cell division
M481_RS01285	COG1609	Transcriptional regulator
M481_RS01305	COG0028	Belongs to the TPP enzyme family
M481_RS01315	COG3328	transposase activity
M481_RS01320	COG1022	Amp-dependent synthetase and ligase
M481_RS01340	COG0473	3-isopropylmalate dehydrogenase activity
M481_RS01355	COG2814	Major facilitator Superfamily
M481_RS01375	COG4143	(ABC) transporter
M481_RS01380	COG1178	ABC-type Fe3 transport system permease component
M481_RS01385	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
M481_RS01390	COG0586	Pfam SNARE associated Golgi protein
M481_RS01395	COG0417	DNA replication proofreading
M481_RS01415	COG2885	chlorophyll binding
M481_RS01415	COG3047	cAMP biosynthetic process
M481_RS01500	COG0564	pseudouridine synthase activity
M481_RS01505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
M481_RS01555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M481_RS01565	COG2966	Psort location CytoplasmicMembrane, score
M481_RS01570	COG1280	lysine exporter protein (LysE YggA)
M481_RS01575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M481_RS01600	COG1047	Peptidyl-prolyl cis-trans
M481_RS01615	COG0196	riboflavin kinase activity
M481_RS01630	COG0583	DNA-binding transcription factor activity
M481_RS01650	COG1584	GPR1 FUN34 yaaH family protein
M481_RS01665	COG0521	Mo-molybdopterin cofactor biosynthetic process
M481_RS01705	COG0745	RESPONSE REGULATOR receiver
M481_RS01710	COG3045	CreA protein
M481_RS01715	COG3708	Transcriptional regulator
M481_RS01715	COG2207	Transcriptional regulator
M481_RS01730	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
M481_RS01735	COG0741	lytic transglycosylase activity
M481_RS01750	COG2199	diguanylate cyclase activity
M481_RS01755	COG2885	chlorophyll binding
M481_RS01760	COG0488	(ABC) transporter
M481_RS01780	COG0560	Phosphoserine phosphatase
M481_RS01785	COG3726	membrane protein affecting hemolysin expression
M481_RS01810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M481_RS01815	COG0084	hydrolase, TatD family'
M481_RS01820	COG4667	esterase of the alpha-beta hydrolase superfamily
M481_RS01830	COG2823	Periplasmic or secreted lipoprotein
M481_RS01840	COG0456	acetyltransferase
M481_RS01845	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
M481_RS01890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M481_RS01895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M481_RS01915	COG0859	PFAM glycosyl transferase family 9
M481_RS01925	COG2390	Transcriptional regulator
M481_RS01970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M481_RS01970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS01970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS01975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M481_RS01980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M481_RS01985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M481_RS01990	COG2207	Transcriptional regulator
M481_RS02000	COG4269	membrane
M481_RS02050	COG2963	transposase activity
M481_RS02065	COG1401	restriction endodeoxyribonuclease activity
M481_RS02090	COG0582	viral genome integration into host DNA
M481_RS02100	COG0795	lipopolysaccharide-transporting ATPase activity
M481_RS02105	COG0795	lipopolysaccharide-transporting ATPase activity
M481_RS02115	COG2927	DNA polymerase III (CHI subunit)
M481_RS02120	COG0525	valine-tRNA ligase activity
M481_RS02130	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
M481_RS02140	COG2731	YhcH YjgK YiaL family protein
M481_RS02150	COG0601	transmembrane transport
M481_RS02155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M481_RS02160	COG0444	Belongs to the ABC transporter superfamily
M481_RS02165	COG4608	Belongs to the ABC transporter superfamily
M481_RS02180	COG2188	Transcriptional regulator
M481_RS02185	COG3624	Phosphonate C-P lyase system protein PhnG
M481_RS02190	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
M481_RS02195	COG3626	phosphonate metabolism
M481_RS02200	COG3627	carbon phosphorus lyase activity
M481_RS02205	COG4107	phosphonate C-P lyase system protein PhnK
M481_RS02210	COG4778	phosphonate C-P lyase system protein PhnL
M481_RS02215	COG3454	Phosphonate metabolism
M481_RS02220	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
M481_RS02225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M481_RS02230	COG0702	epimerase
M481_RS02245	COG3842	ATPase activity
M481_RS02250	COG0395	ABC-type sugar transport system, permease component
M481_RS02255	COG1175	transmembrane transport
M481_RS02260	COG1653	transport
M481_RS02280	COG3153	acetyltransferase
M481_RS02285	COG3154	lipid carrier protein
M481_RS02295	COG0826	peptidase U32
M481_RS02300	COG0826	peptidase U32
M481_RS02310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M481_RS02320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M481_RS02340	COG0513	Belongs to the DEAD box helicase family
M481_RS02360	COG2801	Transposase and inactivated derivatives
M481_RS02380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M481_RS02385	COG0058	SHG alpha-glucan phosphorylase activity
M481_RS02410	COG3275	phosphorelay sensor kinase activity
M481_RS02440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M481_RS02445	COG2095	MarC family integral membrane protein
M481_RS02465	COG3265	gluconokinase activity
M481_RS02470	COG2610	gluconate transmembrane transporter activity
M481_RS02475	COG1609	Transcriptional regulator
M481_RS02480	COG1741	Belongs to the pirin family
M481_RS02500	COG0191	fructose-bisphosphate aldolase activity
M481_RS02515	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS02530	COG2081	HI0933 family
M481_RS02535	COG0306	phosphate transporter
M481_RS02550	COG0589	response to stress
M481_RS02570	COG0339	signal peptide processing
M481_RS02575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M481_RS02580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M481_RS02585	COG3835	regulator
M481_RS02590	COG2610	gluconate transmembrane transporter activity
M481_RS02595	COG1929	Belongs to the glycerate kinase type-1 family
M481_RS02620	COG1295	ribonuclease BN
M481_RS02625	COG2134	cdp-diacylglycerol pyrophosphatase
M481_RS02630	COG2982	Protein involved in outer membrane biogenesis
M481_RS02635	COG2200	EAL domain
M481_RS02640	COG1942	4-Oxalocrotonate Tautomerase
M481_RS02645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M481_RS02650	COG0612	Peptidase, M16
M481_RS02670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M481_RS02675	COG2200	EAL domain
M481_RS02675	COG2199	diguanylate cyclase activity
M481_RS02680	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M481_RS02685	COG4608	Belongs to the ABC transporter superfamily
M481_RS02690	COG0444	Belongs to the ABC transporter superfamily
M481_RS02700	COG0601	transmembrane transport
M481_RS02705	COG0747	negative chemotaxis
M481_RS02715	COG2831	hemolysin activation secretion protein
M481_RS02730	COG2271	Major facilitator Superfamily
M481_RS02735	COG3851	Histidine kinase
M481_RS02740	COG2197	response regulator
M481_RS02745	COG2194	sulfuric ester hydrolase activity
M481_RS02775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M481_RS02800	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
M481_RS02805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M481_RS02810	COG1739	Uncharacterized protein family UPF0029
M481_RS02835	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
M481_RS02855	COG0805	protein transport
M481_RS02865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M481_RS02885	COG1322	Protein conserved in bacteria
M481_RS02890	COG0586	Pfam SNARE associated Golgi protein
M481_RS02895	COG1966	Carbon starvation protein
M481_RS02910	COG0412	Dienelactone hydrolase
M481_RS02920	COG0583	DNA-binding transcription factor activity
M481_RS02925	COG0697	spore germination
M481_RS02930	COG0679	Auxin Efflux Carrier
M481_RS02935	COG0584	glycerophosphoryl diester phosphodiesterase
M481_RS02995	COG0410	ABC transporter
M481_RS03005	COG4177	L-phenylalanine transmembrane transporter activity
M481_RS03015	COG0683	leucine binding
M481_RS03040	COG2177	Part of the ABC transporter FtsEX involved in
M481_RS03045	COG2884	Cell division ATP-binding protein ftsE
M481_RS03050	COG0552	protein localization to endoplasmic reticulum
M481_RS03050	COG0552	protein localization to endoplasmic reticulum
M481_RS03060	COG0742	ribosomal rna small subunit methyltransferase
M481_RS03065	COG3776	membrane
M481_RS03080	COG3714	YhhN family
M481_RS03095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M481_RS03105	COG0247	lactate metabolic process
M481_RS03115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M481_RS03125	COG0584	glycerophosphoryl diester phosphodiesterase
M481_RS03135	COG0561	phosphatase activity
M481_RS03140	COG2267	carboxylic ester hydrolase activity
M481_RS03145	COG1280	lysine exporter protein (LysE YggA)
M481_RS03150	COG1280	lysine exporter protein (LysE YggA)
M481_RS03155	COG0514	ATP-dependent DNA helicase (RecQ)
M481_RS03160	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
M481_RS03165	COG2050	protein possibly involved in aromatic compounds catabolism
M481_RS03180	COG5564	TIM-barrel signal transduction protein
M481_RS03185	COG5441	Belongs to the UPF0261 family
M481_RS03195	COG0210	DNA helicase
M481_RS03200	COG1011	Hydrolase
M481_RS03205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M481_RS03210	COG3159	Protein conserved in bacteria
M481_RS03230	COG3072	Adenylate cyclase
M481_RS03240	COG1587	Uroporphyrinogen-III synthase
M481_RS03245	COG2959	enzyme of heme biosynthesis
M481_RS03250	COG3071	HemY protein
M481_RS03280	COG1113	amino acid transport
M481_RS03300	COG2244	polysaccharide biosynthetic process
M481_RS03305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M481_RS03310	COG0456	acetyltransferase
M481_RS03315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M481_RS03320	COG1088	dTDP-glucose 4,6-dehydratase activity
M481_RS03325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M481_RS03330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M481_RS03335	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M481_RS03340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M481_RS03345	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M481_RS03350	COG3118	belongs to the thioredoxin family
M481_RS03375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M481_RS03395	COG3121	Chaperone
M481_RS03410	COG3121	Chaperone
M481_RS03450	COG0583	DNA-binding transcription factor activity
M481_RS03490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M481_RS03495	COG3978	acetolactate synthase activity
M481_RS03510	COG3085	chromosome segregation
M481_RS03520	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS03525	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS03530	COG1129	ABC transporter
M481_RS03535	COG1879	ABC-type sugar transport system periplasmic component
M481_RS03585	COG0151	Belongs to the GarS family
M481_RS03605	COG1515	deoxyribonuclease V activity
M481_RS03645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M481_RS03700	COG0250	Participates in transcription elongation, termination and antitermination
M481_RS03760	COG2986	histidine ammonia-lyase
M481_RS03790	COG4607	ABC-type enterochelin transport system periplasmic component
M481_RS03800	COG4605	iron ion homeostasis
M481_RS03805	COG4604	ABC transporter, ATP-binding protein
M481_RS03845	COG0582	viral genome integration into host DNA
M481_RS03850	COG1609	Transcriptional regulator
M481_RS03850	COG2207	Transcriptional regulator
M481_RS03855	COG4214	carbohydrate transport
M481_RS03865	COG4213	ABC transporter substrate-binding protein
M481_RS03875	COG1070	Carbohydrate kinase
M481_RS03885	COG3121	Chaperone
M481_RS03900	COG3274	enterobacterial common antigen metabolic process
M481_RS03915	COG2801	Transposase and inactivated derivatives
M481_RS03925	COG0460	homoserine dehydrogenase
M481_RS03925	COG0527	aspartate kinase activity
M481_RS03930	COG0626	cystathionine gamma-synthase activity
M481_RS03945	COG4682	membrane
M481_RS03955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M481_RS03965	COG1609	Transcriptional regulator
M481_RS03970	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M481_RS03985	COG1575	Belongs to the MenA family. Type 1 subfamily
M481_RS04035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M481_RS04040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M481_RS04045	COG1494	fructose-1,6-bisphosphatase
M481_RS04055	COG3152	Membrane
M481_RS04070	COG0583	DNA-binding transcription factor activity
M481_RS04075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M481_RS04080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M481_RS04095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M481_RS04115	COG3678	ATP-independent chaperone mediated protein folding
M481_RS04120	COG0745	RESPONSE REGULATOR receiver
M481_RS04125	COG2205	protein histidine kinase activity
M481_RS04130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M481_RS04130	COG2169	Transcriptional regulator
M481_RS04135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M481_RS04140	COG1045	serine acetyltransferase
M481_RS04160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M481_RS04165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M481_RS04175	COG4942	peptidase
M481_RS04190	COG0156	8-amino-7-oxononanoate synthase activity
M481_RS04200	COG0859	PFAM glycosyl transferase family 9
M481_RS04205	COG0859	PFAM glycosyl transferase family 9
M481_RS04210	COG1519	Transferase
M481_RS04245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M481_RS04270	COG1561	YicC-like family, N-terminal region
M481_RS04275	COG2860	membrane
M481_RS04295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M481_RS04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M481_RS04305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M481_RS04310	COG0786	glutamate:sodium symporter activity
M481_RS04315	COG2233	PERMEase
M481_RS04320	COG2982	Protein involved in outer membrane biogenesis
M481_RS04325	COG0456	acetyltransferase
M481_RS04350	COG1011	Hydrolase
M481_RS04365	COG0174	glutamine synthetase
M481_RS04370	COG3852	Histidine kinase
M481_RS04380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M481_RS04395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M481_RS04395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M481_RS04400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M481_RS04405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M481_RS04410	COG3084	Protein conserved in bacteria
M481_RS04420	COG1763	Mo-molybdopterin cofactor biosynthetic process
M481_RS04425	COG3328	transposase activity
M481_RS04455	COG2186	Transcriptional regulator
M481_RS04460	COG0477	Major facilitator Superfamily
M481_RS04500	COG1522	sequence-specific DNA binding
M481_RS04505	COG0716	FMN binding
M481_RS04520	COG3312	ion transport
M481_RS04575	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M481_RS04580	COG0573	inorganic phosphate transmembrane transporter activity
M481_RS04585	COG0581	inorganic phosphate transmembrane transporter activity
M481_RS04595	COG0704	Plays a role in the regulation of phosphate uptake
M481_RS04605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS04610	COG0765	amino acid transport
M481_RS04615	COG0765	amino acid transport
M481_RS04620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M481_RS04625	COG2252	PERMEase
M481_RS04650	COG0706	membrane insertase activity
M481_RS04660	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M481_RS04670	COG0592	DNA-directed DNA polymerase activity
M481_RS04685	COG0187	DNA topoisomerase II activity
M481_RS04690	COG0561	phosphatase activity
M481_RS04695	COG2801	Transposase and inactivated derivatives
M481_RS04705	COG2423	ornithine cyclodeaminase activity
M481_RS04710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M481_RS04715	COG0823	Involved in the tonB-independent uptake of proteins
M481_RS04720	COG0823	Involved in the tonB-independent uptake of proteins
M481_RS04725	COG5645	(Lipo)protein
M481_RS04745	COG3977	Valine--pyruvate aminotransferase
M481_RS04755	COG0366	Alpha amylase catalytic
M481_RS04770	COG2885	chlorophyll binding
M481_RS04780	COG2818	Glycosylase
M481_RS04800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS04800	COG2213	PTS system mannitol-specific
M481_RS04810	COG3722	fumarate hydratase activity
M481_RS04835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M481_RS04845	COG3383	formate dehydrogenase (NAD+) activity
M481_RS04845	COG0243	molybdopterin cofactor binding
M481_RS04850	COG0243	molybdopterin cofactor binding
M481_RS04850	COG3383	formate dehydrogenase (NAD+) activity
M481_RS04855	COG0437	4 iron, 4 sulfur cluster binding
M481_RS04860	COG2864	formate dehydrogenase
M481_RS04875	COG3276	selenocysteine insertion sequence binding
M481_RS04885	COG3328	transposase activity
M481_RS04915	COG2801	Transposase and inactivated derivatives
M481_RS04925	COG1349	DNA-binding transcription factor activity
M481_RS04945	COG0058	SHG alpha-glucan phosphorylase activity
M481_RS04950	COG1640	4-alpha-glucanotransferase
M481_RS04985	COG1918	ferrous iron import across plasma membrane
M481_RS04995	COG2183	response to ionizing radiation
M481_RS05000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M481_RS05025	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M481_RS05030	COG1011	Hydrolase
M481_RS05045	COG0494	nUDIX hydrolase
M481_RS05050	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M481_RS05080	COG4796	Type ii and iii secretion system protein
M481_RS05105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M481_RS05110	COG0546	phosphoglycolate phosphatase activity
M481_RS05115	COG0180	Tryptophanyl-tRNA synthetase
M481_RS05135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M481_RS05140	COG0402	S-adenosylhomocysteine deaminase activity
M481_RS05165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M481_RS05170	COG0433	COG0433 Predicted ATPase
M481_RS05185	COG1289	transmembrane transporter activity
M481_RS05195	COG1765	OsmC-like protein
M481_RS05205	COG3954	Phosphoribulokinase
M481_RS05215	COG0429	hydrolase of the alpha beta-hydrolase fold
M481_RS05225	COG4521	taurine ABC transporter
M481_RS05235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M481_RS05240	COG2175	clavaminate synthase activity
M481_RS05250	COG1216	Glycosyl transferase, family 2
M481_RS05255	COG0488	(ABC) transporter
M481_RS05270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M481_RS05275	COG1047	Peptidyl-prolyl cis-trans
M481_RS05285	COG0545	Peptidyl-prolyl cis-trans isomerase
M481_RS05290	COG2964	Protein conserved in bacteria
M481_RS05315	COG0049	tRNA binding
M481_RS05355	COG0051	transcription antitermination factor activity, RNA binding
M481_RS05370	COG0089	rRNA binding
M481_RS05380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M481_RS05390	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
M481_RS05395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M481_RS05405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M481_RS05410	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M481_RS05450	COG1841	ribosomal large subunit assembly
M481_RS05460	COG0201	protein transport
M481_RS05465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M481_RS05480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M481_RS05495	COG0789	Transcriptional regulator
M481_RS05500	COG3036	rescue of stalled ribosome
M481_RS05530	COG0758	DNA mediated transformation
M481_RS05540	COG0551	DNA topoisomerase type I activity
M481_RS05555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M481_RS05590	COG2801	Transposase and inactivated derivatives
M481_RS05615	COG3162	membrane
M481_RS05625	COG1301	dicarboxylic acid transport
M481_RS05735	COG2391	methyltransferase activity
M481_RS05740	COG0425	Belongs to the sulfur carrier protein TusA family
M481_RS05745	COG0583	DNA-binding transcription factor activity
M481_RS05750	COG0814	amino acid
M481_RS05755	COG0626	cystathionine gamma-synthase activity
M481_RS05765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M481_RS05770	COG4558	Periplasmic binding protein
M481_RS05775	COG3720	iron ion transport
M481_RS05780	COG4771	TonB-dependent receptor
M481_RS05790	COG0702	epimerase
M481_RS05795	COG3721	Heme iron utilization protein
M481_RS05820	COG1358	cellular component organization or biogenesis
M481_RS05880	COG3121	Chaperone
M481_RS05925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M481_RS05935	COG0735	belongs to the Fur family
M481_RS05940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M481_RS05965	COG1448	Aminotransferase
M481_RS05970	COG2315	Protein conserved in bacteria
M481_RS05975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M481_RS05980	COG0629	single-stranded DNA binding
M481_RS05990	COG1454	alcohol dehydrogenase
M481_RS06060	COG1309	transcriptional regulator
M481_RS06065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M481_RS06065	COG0493	'glutamate synthase
M481_RS06070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M481_RS06075	COG3383	formate dehydrogenase (NAD+) activity
M481_RS06090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M481_RS06135	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
M481_RS06145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M481_RS06150	COG1053	succinate dehydrogenase
M481_RS06165	COG3264	Mechanosensitive ion channel
M481_RS06165	COG1511	domain protein
M481_RS06185	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M481_RS06195	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M481_RS06200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M481_RS06200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M481_RS06205	COG0802	atpase or kinase
M481_RS06210	COG0860	N-Acetylmuramoyl-L-alanine amidase
M481_RS06230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M481_RS06235	COG0330	HflC and HflK could
M481_RS06240	COG0330	HflC and HflK could
M481_RS06245	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
M481_RS06265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M481_RS06270	COG1960	acyl-CoA dehydrogenase activity
M481_RS06275	COG3650	response to hydrogen peroxide
M481_RS06290	COG1073	alpha beta
M481_RS06310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M481_RS06330	COG3061	Opacity-associated protein A
M481_RS06335	COG0545	Peptidyl-prolyl cis-trans isomerase
M481_RS06345	COG0737	Belongs to the 5'-nucleotidase family
M481_RS06355	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
M481_RS06365	COG1253	flavin adenine dinucleotide binding
M481_RS06375	COG0729	surface antigen
M481_RS06380	COG2911	Protein conserved in bacteria
M481_RS06385	COG2105	PFAM AIG2 family protein
M481_RS06390	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M481_RS06400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M481_RS06425	COG3423	Transcriptional regulator
M481_RS06435	COG0142	geranyltranstransferase activity
M481_RS06450	COG0697	spore germination
M481_RS06460	COG0642	Histidine kinase
M481_RS06465	COG0745	RESPONSE REGULATOR receiver
M481_RS06470	COG2027	D-alanyl-D-alanine carboxypeptidase
M481_RS06480	COG1534	Rna-binding protein
M481_RS06495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M481_RS06505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M481_RS06525	COG0195	Participates in both transcription termination and antitermination
M481_RS06550	COG2801	Transposase and inactivated derivatives
M481_RS06570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M481_RS06590	COG1629	transport
M481_RS06615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M481_RS06620	COG0678	peroxiredoxin activity
M481_RS06620	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M481_RS06690	COG5544	Lipoprotein
M481_RS06695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M481_RS06700	COG0045	succinate-CoA ligase (ADP-forming) activity
M481_RS06700	COG1042	CoA-binding domain protein
M481_RS06700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M481_RS06705	COG3148	PFAM DTW domain containing protein
M481_RS06710	COG3118	belongs to the thioredoxin family
M481_RS06715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M481_RS06720	COG2814	Major facilitator Superfamily
M481_RS06725	COG1566	PFAM secretion protein HlyD family protein
M481_RS06730	COG1846	Transcriptional regulator
M481_RS06740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M481_RS06745	COG2814	Major facilitator Superfamily
M481_RS06785	COG0765	amino acid transport
M481_RS06795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M481_RS06810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M481_RS06825	COG0436	Aminotransferase
M481_RS06865	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
M481_RS06880	COG1960	acyl-CoA dehydrogenase activity
M481_RS06890	COG0121	glutamine amidotransferase
M481_RS06895	COG3034	peptidoglycan biosynthetic process
M481_RS06905	COG1805	sodium ion transport
M481_RS06910	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M481_RS06930	COG1477	protein flavinylation
M481_RS06950	COG2195	Cleaves the N-terminal amino acid of tripeptides
M481_RS07010	COG2226	methyltransferase
M481_RS07045	COG1940	carbohydrate kinase activity
M481_RS07050	COG0419	ATPase involved in DNA repair
M481_RS07055	COG0420	3'-5' exonuclease activity
M481_RS07065	COG0745	RESPONSE REGULATOR receiver
M481_RS07070	COG5002	protein histidine kinase activity
M481_RS07090	COG0366	Alpha amylase catalytic
M481_RS07110	COG0450	alkyl hydroperoxide reductase
M481_RS07130	COG1862	Preprotein translocase
M481_RS07135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M481_RS07140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M481_RS07165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M481_RS07165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M481_RS07180	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M481_RS07185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M481_RS07200	COG0142	geranyltranstransferase activity
M481_RS07220	COG0693	protein deglycase activity
M481_RS07225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M481_RS07235	COG2814	Major facilitator Superfamily
M481_RS07245	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M481_RS07250	COG1845	cytochrome c oxidase, subunit III
M481_RS07255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M481_RS07260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M481_RS07270	COG2223	nitrite transmembrane transporter activity
M481_RS07275	COG3056	Lipoprotein
M481_RS07280	COG0271	Belongs to the BolA IbaG family
M481_RS07305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M481_RS07310	COG0776	regulation of translation
M481_RS07325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M481_RS07330	COG1555	photosystem II stabilization
M481_RS07335	COG0824	Thioesterase
M481_RS07345	COG4533	DNA binding
M481_RS07360	COG1522	sequence-specific DNA binding
M481_RS07365	COG1132	(ABC) transporter
M481_RS07370	COG1132	(ABC) transporter
M481_RS07375	COG0347	Belongs to the P(II) protein family
M481_RS07380	COG0004	ammonium transporteR
M481_RS07385	COG1946	Acyl-CoA thioesterase
M481_RS07390	COG3126	Type III secretion system lipoprotein chaperone (YscW)
M481_RS07395	COG3695	enzyme binding
M481_RS07415	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M481_RS07425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M481_RS07430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M481_RS07435	COG1309	transcriptional regulator
M481_RS07440	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M481_RS07445	COG3264	Mechanosensitive ion channel
M481_RS07445	COG1196	nuclear chromosome segregation
M481_RS07470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M481_RS07500	COG0543	2 iron, 2 sulfur cluster binding
M481_RS07500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M481_RS07520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M481_RS07560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M481_RS07580	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M481_RS07585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M481_RS07590	COG4651	solute:proton antiporter activity
M481_RS07590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M481_RS07600	COG0737	Belongs to the 5'-nucleotidase family
M481_RS07605	COG0737	Belongs to the 5'-nucleotidase family
M481_RS07610	COG0737	Belongs to the 5'-nucleotidase family
M481_RS07625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M481_RS07630	COG3735	TraB family
M481_RS07635	COG2217	Heavy metal translocating P-type atpase
M481_RS07640	COG0789	Transcriptional regulator
M481_RS07645	COG1585	Membrane protein implicated in regulation of membrane protease activity
M481_RS07650	COG0330	HflC and HflK could
M481_RS07655	COG3118	belongs to the thioredoxin family
M481_RS07660	COG0300	oxidoreductase activity
M481_RS07665	COG2755	lipolytic protein G-D-S-L family
M481_RS07670	COG4181	ATPase activity
M481_RS07675	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M481_RS07680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M481_RS07685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M481_RS07695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M481_RS07715	COG2501	S4 domain
M481_RS07760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M481_RS07765	COG4589	Belongs to the CDS family
M481_RS07775	COG2267	carboxylic ester hydrolase activity
M481_RS07780	COG0671	phosphoesterase, PA-phosphatase related
M481_RS07780	COG2453	phosphatase
M481_RS07810	COG0667	Aldo Keto reductase
M481_RS07815	COG0656	L-ascorbic acid biosynthetic process
M481_RS07835	COG1472	Belongs to the glycosyl hydrolase 3 family
M481_RS07850	COG3328	transposase activity
M481_RS07855	COG2850	peptidyl-arginine hydroxylation
M481_RS07905	COG3423	Transcriptional regulator
M481_RS07910	COG4953	penicillin-binding protein 1C
M481_RS07915	COG2373	Large extracellular alpha-helical protein
M481_RS07950	COG1129	ABC transporter
M481_RS07955	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS07960	COG0673	inositol 2-dehydrogenase activity
M481_RS07965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M481_RS07975	COG3718	enzyme involved in inositol metabolism
M481_RS07985	COG5265	(ABC) transporter
M481_RS08010	COG2197	response regulator
M481_RS08015	COG1278	Cold shock
M481_RS08025	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M481_RS08035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M481_RS08055	COG1686	Belongs to the peptidase S11 family
M481_RS08060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M481_RS08065	COG0772	Belongs to the SEDS family
M481_RS08070	COG0768	penicillin binding
M481_RS08080	COG0799	negative regulation of ribosome biogenesis
M481_RS08090	COG1466	dna polymerase III delta subunit
M481_RS08105	COG2888	peptidyl-tyrosine sulfation
M481_RS08110	COG1126	abc transporter atp-binding protein
M481_RS08115	COG0765	amino acid transport
M481_RS08120	COG0765	amino acid transport
M481_RS08130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
M481_RS08135	COG4535	Mg2 and Co2 transporter CorC
M481_RS08145	COG1702	phosphate starvation-inducible protein PhoH
M481_RS08155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M481_RS08195	COG0367	asparagine synthase
M481_RS08200	COG0647	UMP catabolic process
M481_RS08205	COG1940	carbohydrate kinase activity
M481_RS08205	COG1846	Transcriptional regulator
M481_RS08210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M481_RS08220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M481_RS08220	COG2190	(PTS) system
M481_RS08220	COG1263	PTS System
M481_RS08240	COG0735	belongs to the Fur family
M481_RS08260	COG0596	Alpha beta hydrolase
M481_RS08270	COG0582	viral genome integration into host DNA
M481_RS08275	COG2963	transposase activity
M481_RS08280	COG0582	viral genome integration into host DNA
M481_RS08305	COG3657	addiction module killer protein
M481_RS08365	COG0582	viral genome integration into host DNA
M481_RS08385	COG2867	negative regulation of translational initiation
M481_RS08395	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M481_RS08400	COG0497	DNA recombination
M481_RS08405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M481_RS08420	COG2009	succinate dehydrogenase
M481_RS08425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M481_RS08430	COG1053	succinate dehydrogenase
M481_RS08440	COG0567	Dehydrogenase, E1 component
M481_RS08445	COG0508	dehydrogenase complex catalyzes the overall conversion of
M481_RS08455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M481_RS08465	COG1271	oxidase subunit
M481_RS08470	COG1294	oxidase, subunit
M481_RS08475	COG4890	Cyd operon protein YbgT
M481_RS08480	COG3790	cyd operon protein YbgE
M481_RS08485	COG0824	Thioesterase
M481_RS08490	COG0811	peptide transport
M481_RS08495	COG0848	biopolymer transport protein
M481_RS08500	COG3064	Membrane
M481_RS08500	COG3064	Membrane
M481_RS08510	COG2885	chlorophyll binding
M481_RS08515	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
M481_RS08550	COG1230	cation diffusion facilitator family transporter
M481_RS08570	COG2017	converts alpha-aldose to the beta-anomer
M481_RS08585	COG1085	galactose-1-phosphate uridylyltransferase
M481_RS08590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M481_RS08605	COG1119	ATPase activity
M481_RS08610	COG3585	molybdate ion transport
M481_RS08610	COG2005	Transcriptional regulator
M481_RS08620	COG0725	ABC transporter, periplasmic molybdate-binding protein
M481_RS08625	COG4149	molybdate abc transporter
M481_RS08635	COG0561	phosphatase activity
M481_RS08660	COG2226	methyltransferase
M481_RS08670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M481_RS08680	COG4628	conserved protein (DUF2132)
M481_RS08685	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M481_RS08695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M481_RS08705	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M481_RS08710	COG0314	molybdopterin synthase activity
M481_RS08715	COG0670	Belongs to the BI1 family
M481_RS08745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M481_RS08750	COG0583	DNA-binding transcription factor activity
M481_RS08760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M481_RS08765	COG2211	Major facilitator Superfamily
M481_RS08780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M481_RS08790	COG1686	Belongs to the peptidase S11 family
M481_RS08795	COG0277	FAD linked oxidase domain protein
M481_RS08815	COG2261	transglycosylase associated protein
M481_RS08825	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
M481_RS08840	COG4807	Protein conserved in bacteria
M481_RS08860	COG1122	ATPase activity
M481_RS08880	COG2897	thiosulfate sulfurtransferase activity
M481_RS08885	COG1732	Glycine betaine
M481_RS08890	COG1174	glycine betaine transport
M481_RS08895	COG1125	glycine betaine transport
M481_RS08900	COG1174	glycine betaine transport
M481_RS08905	COG0531	amino acid
M481_RS08910	COG1982	Orn Lys Arg decarboxylase major
M481_RS08915	COG3328	transposase activity
M481_RS08920	COG1982	Orn Lys Arg decarboxylase major
M481_RS08930	COG0697	spore germination
M481_RS08955	COG0814	amino acid
M481_RS08970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M481_RS09000	COG0784	Response regulator, receiver
M481_RS09000	COG2205	protein histidine kinase activity
M481_RS09010	COG2198	Histidine kinase
M481_RS09010	COG0642	Histidine kinase
M481_RS09015	COG0642	Histidine kinase
M481_RS09015	COG2198	Histidine kinase
M481_RS09040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M481_RS09085	COG3395	kinase activity
M481_RS09090	COG0235	Class ii aldolase
M481_RS09095	COG1349	DNA-binding transcription factor activity
M481_RS09100	COG3622	Belongs to the hyi family
M481_RS09120	COG4386	tail sheath protein
M481_RS09160	COG3299	homolog of phage Mu protein gp47
M481_RS09180	COG1737	Transcriptional regulator
M481_RS09185	COG2723	6-phospho-beta-galactosidase activity
M481_RS09200	COG3157	Type VI secretion system effector, Hcp
M481_RS09210	COG3083	sulfuric ester hydrolase activity
M481_RS09215	COG3082	Protein of unknown function (DUF1414)
M481_RS09235	COG1061	Type III restriction enzyme res subunit
M481_RS09240	COG1187	pseudouridine synthase activity
M481_RS09245	COG2814	Major facilitator Superfamily
M481_RS09255	COG4172	Belongs to the ABC transporter superfamily
M481_RS09260	COG4239	(ABC) transporter, permease
M481_RS09265	COG4174	ABC transporter (Permease)
M481_RS09270	COG4166	transmembrane transport
M481_RS09275	COG2200	EAL domain
M481_RS09280	COG0791	NLP P60 protein
M481_RS09285	COG0671	phosphoesterase, PA-phosphatase related
M481_RS09290	COG0523	cobalamin synthesis protein
M481_RS09305	COG0246	Mannitol dehydrogenase
M481_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS09365	COG1129	ABC transporter
M481_RS09375	COG0494	nUDIX hydrolase
M481_RS09385	COG1105	Belongs to the carbohydrate kinase PfkB family
M481_RS09390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M481_RS09390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M481_RS09390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M481_RS09395	COG3710	Transcriptional regulator
M481_RS09410	COG3121	Chaperone
M481_RS09415	COG3188	usher protein
M481_RS09425	COG2855	membrane
M481_RS09430	COG0583	DNA-binding transcription factor activity
M481_RS09435	COG0833	amino acid
M481_RS09450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M481_RS09460	COG4771	TonB-dependent receptor
M481_RS09465	COG0625	glutathione transferase activity
M481_RS09490	COG2011	ABC-type metal ion transport system permease component
M481_RS09495	COG1686	Belongs to the peptidase S11 family
M481_RS09505	COG0814	amino acid
M481_RS09510	COG1349	DNA-binding transcription factor activity
M481_RS09520	COG0671	phosphoesterase, PA-phosphatase related
M481_RS09555	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M481_RS09560	COG3842	ATPase activity
M481_RS09565	COG1176	ABC-type spermidine putrescine transport system, permease component I
M481_RS09570	COG1177	transmembrane transport
M481_RS09585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS09615	COG1120	ATPase activity
M481_RS09635	COG4160	amino acid transport
M481_RS09640	COG4215	(ABC) transporter
M481_RS09645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS09650	COG1126	abc transporter atp-binding protein
M481_RS09655	COG1605	Chorismate mutase
M481_RS09665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M481_RS09670	COG0702	epimerase
M481_RS09675	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
M481_RS09680	COG0028	Belongs to the TPP enzyme family
M481_RS09685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M481_RS09695	COG2431	L-lysine efflux transmembrane transporter activity
M481_RS09700	COG3593	DNA synthesis involved in DNA repair
M481_RS09705	COG2990	Protein conserved in bacteria
M481_RS09710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M481_RS09720	COG1278	Cold shock
M481_RS09730	COG0542	response to heat
M481_RS09740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M481_RS09750	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M481_RS09765	COG0492	ferredoxin-NADP+ reductase activity
M481_RS09775	COG3107	peptidoglycan biosynthetic process
M481_RS09775	COG1674	ftsk spoiiie
M481_RS09785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M481_RS09800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M481_RS09810	COG1882	Formate acetyltransferase
M481_RS09815	COG2116	formate transmembrane transporter activity
M481_RS09820	COG1944	ATP diphosphatase activity
M481_RS09825	COG0252	asparaginase activity
M481_RS09830	COG5295	Hep Hag repeat protein
M481_RS09830	COG5295	Hep Hag repeat protein
M481_RS09855	COG0539	negative regulation of cytoplasmic translation
M481_RS09870	COG0658	competence protein
M481_RS09870	COG2333	competence protein COMEC
M481_RS09885	COG5383	Protein conserved in bacteria
M481_RS09895	COG1278	Cold shock
M481_RS09910	COG3173	Aminoglycoside phosphotransferase
M481_RS09920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M481_RS09950	COG2989	Protein conserved in bacteria
M481_RS09955	COG3108	Peptidase M15
M481_RS09960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M481_RS09965	COG1448	Aminotransferase
M481_RS09985	COG0308	aminopeptidase N
M481_RS10000	COG3217	Mosc domain protein beta barrel domain protein
M481_RS10000	COG0633	Ferredoxin
M481_RS10010	COG0488	(ABC) transporter
M481_RS10015	COG2995	paraquat-inducible protein a
M481_RS10020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M481_RS10020	COG3008	intermembrane lipid transfer
M481_RS10025	COG3009	Protein conserved in bacteria
M481_RS10035	COG3130	regulation of translation
M481_RS10050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M481_RS10055	COG1737	Transcriptional regulator
M481_RS10065	COG0560	Phosphoserine phosphatase
M481_RS10105	COG2205	protein histidine kinase activity
M481_RS10110	COG3170	Tfp pilus assembly protein FimV
M481_RS10115	COG2204	response regulator
M481_RS10120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M481_RS10120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M481_RS10125	COG0347	Belongs to the P(II) protein family
M481_RS10130	COG2188	Transcriptional regulator
M481_RS10145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M481_RS10145	COG1017	nitric oxide dioxygenase activity
M481_RS10165	COG2814	Major facilitator Superfamily
M481_RS10170	COG3711	transcriptional antiterminator
M481_RS10175	COG3683	transport system, periplasmic component
M481_RS10180	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
M481_RS10200	COG1104	cysteine desulfurase activity
M481_RS10205	COG0822	iron-sulfur transferase activity
M481_RS10220	COG0443	Heat shock 70 kDa protein
M481_RS10225	COG0633	Ferredoxin
M481_RS10230	COG2975	iron-sulfur cluster assembly
M481_RS10250	COG3468	outer membrane autotransporter barrel domain protein
M481_RS10255	COG3468	outer membrane autotransporter barrel domain protein
M481_RS10300	COG2976	Protein conserved in bacteria
M481_RS10305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M481_RS10320	COG1645	bacterial-type flagellum-dependent swarming motility
M481_RS10330	COG0516	GMP reductase activity
M481_RS10330	COG0517	IMP dehydrogenase activity
M481_RS10385	COG3328	transposase activity
M481_RS10400	COG0351	phosphomethylpyrimidine kinase
M481_RS10420	COG0826	peptidase U32
M481_RS10425	COG3422	double-strand break repair
M481_RS10430	COG0745	RESPONSE REGULATOR receiver
M481_RS10435	COG2205	protein histidine kinase activity
M481_RS10460	COG3842	ATPase activity
M481_RS10470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M481_RS10480	COG1176	ABC-type spermidine putrescine transport system, permease component I
M481_RS10485	COG1177	transmembrane transport
M481_RS10490	COG0443	Heat shock 70 kDa protein
M481_RS10495	COG2239	Acts as a magnesium transporter
M481_RS10510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M481_RS10520	COG0581	inorganic phosphate transmembrane transporter activity
M481_RS10540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M481_RS10545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M481_RS10570	COG1393	Belongs to the ArsC family
M481_RS10575	COG4783	chaperone-mediated protein folding
M481_RS10580	COG0628	permease
M481_RS10600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M481_RS10605	COG2716	regulation of RNA biosynthetic process
M481_RS10615	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
M481_RS10635	COG2321	neutral zinc metallopeptidase
M481_RS10655	COG1876	peptidase activity
M481_RS10665	COG1393	Belongs to the ArsC family
M481_RS10680	COG1175	transmembrane transport
M481_RS10685	COG3842	ATPase activity
M481_RS10690	COG3119	arylsulfatase activity
M481_RS10695	COG0641	radical SAM
M481_RS10700	COG1988	membrane-bound metal-dependent
M481_RS10710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M481_RS10720	COG2197	response regulator
M481_RS10725	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
M481_RS10725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M481_RS10730	COG3062	negative regulation of establishment of protein localization
M481_RS10740	COG3043	anaerobic respiration
M481_RS10745	COG3005	denitrification pathway
M481_RS10800	COG3111	PFAM Bacterial OB fold (BOF) protein
M481_RS10810	COG2837	iron assimilation
M481_RS10815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M481_RS10825	COG4886	Leucine-rich repeat (LRR) protein
M481_RS10835	COG2731	YhcH YjgK YiaL family protein
M481_RS10845	COG1737	Transcriptional regulator
M481_RS10855	COG4150	thiosulfate binding
M481_RS10860	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M481_RS10865	COG4208	sulfate ABC transporter
M481_RS10870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M481_RS10885	COG0745	RESPONSE REGULATOR receiver
M481_RS10890	COG5002	protein histidine kinase activity
M481_RS10890	COG3850	Histidine kinase
M481_RS10900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M481_RS10920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M481_RS10935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M481_RS10940	COG0745	RESPONSE REGULATOR receiver
M481_RS10945	COG2205	protein histidine kinase activity
M481_RS10970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS10980	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
M481_RS10995	COG3530	Putative quorum-sensing-regulated virulence factor
M481_RS11060	COG0667	Aldo Keto reductase
M481_RS11085	COG0436	Aminotransferase
M481_RS11090	COG3038	cytochrome b561
M481_RS11120	COG3381	protein complex oligomerization
M481_RS11125	COG3302	dmso reductase anchor subunit
M481_RS11130	COG0437	4 iron, 4 sulfur cluster binding
M481_RS11135	COG0243	molybdopterin cofactor binding
M481_RS11170	COG2951	lytic endotransglycosylase activity
M481_RS11230	COG3121	Chaperone
M481_RS11235	COG3188	usher protein
M481_RS11240	COG3328	transposase activity
M481_RS11245	COG3188	usher protein
M481_RS11340	COG2824	Alkylphosphonate utilization operon protein PhnA
M481_RS11350	COG1704	LemA family
M481_RS11370	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M481_RS11375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M481_RS11380	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M481_RS11390	COG1138	Cytochrome C-type biogenesis protein
M481_RS11395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M481_RS11400	COG4235	cytochrome complex assembly
M481_RS11400	COG3088	subunit of a heme lyase
M481_RS11405	COG3088	subunit of a heme lyase
M481_RS11405	COG4235	cytochrome complex assembly
M481_RS11420	COG3691	Protein conserved in bacteria
M481_RS11435	COG2062	phosphohistidine phosphatase, SixA
M481_RS11445	COG2890	protein-(glutamine-N5) methyltransferase activity
M481_RS11460	COG0730	response to heat
M481_RS11465	COG3101	peptidyl-lysine hydroxylation
M481_RS11480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M481_RS11485	COG1794	racemase activity, acting on amino acids and derivatives
M481_RS11500	COG0697	spore germination
M481_RS11520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M481_RS11530	COG0586	Pfam SNARE associated Golgi protein
M481_RS11540	COG0285	dihydrofolate synthase activity
M481_RS11545	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
M481_RS11550	COG1286	toxin biosynthetic process
M481_RS11555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M481_RS11565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS11570	COG4215	(ABC) transporter
M481_RS11575	COG4160	amino acid transport
M481_RS11580	COG4598	ABC transporter
M481_RS11585	COG1090	epimerase
M481_RS11600	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
M481_RS11605	COG3037	sugar-specific permease SgaT UlaA
M481_RS11620	COG1609	Transcriptional regulator
M481_RS11625	COG0857	belongs to the CobB CobQ family
M481_RS11625	COG0280	phosphate acetyltransferase
M481_RS11650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M481_RS11655	COG0490	domain, Protein
M481_RS11655	COG0471	metal ion transport
M481_RS11670	COG0436	Aminotransferase
M481_RS11680	COG0583	DNA-binding transcription factor activity
M481_RS11690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M481_RS11710	COG1034	ATP synthesis coupled electron transport
M481_RS11725	COG0839	Belongs to the complex I subunit 6 family
M481_RS11735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M481_RS11740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M481_RS11755	COG2731	YhcH YjgK YiaL family protein
M481_RS11760	COG3265	gluconokinase activity
M481_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS11770	COG1649	PFAM Uncharacterised BCR, COG1649
M481_RS11775	COG1609	Transcriptional regulator
M481_RS11785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M481_RS11800	COG0129	dihydroxy-acid dehydratase activity
M481_RS11815	COG4575	ribosome binding
M481_RS11825	COG1169	isochorismate synthase
M481_RS11840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M481_RS11855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M481_RS11880	COG1126	abc transporter atp-binding protein
M481_RS11885	COG0765	amino acid transport
M481_RS11890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS11920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M481_RS11940	COG1063	alcohol dehydrogenase
M481_RS11945	COG1879	ABC-type sugar transport system periplasmic component
M481_RS11955	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS11960	COG1609	Transcriptional regulator
M481_RS11965	COG0583	DNA-binding transcription factor activity
M481_RS11970	COG0473	3-isopropylmalate dehydrogenase activity
M481_RS11980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M481_RS11985	COG4638	Rieske (2fe-2S)
M481_RS11990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M481_RS11995	COG2831	hemolysin activation secretion protein
M481_RS12000	COG3210	domain, Protein
M481_RS12020	COG3210	domain, Protein
M481_RS12040	COG3210	domain, Protein
M481_RS12050	COG3842	ATPase activity
M481_RS12060	COG1609	Transcriptional regulator
M481_RS12075	COG0395	ABC-type sugar transport system, permease component
M481_RS12080	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
M481_RS12100	COG0668	transmembrane transport
M481_RS12105	COG1518	maintenance of DNA repeat elements
M481_RS12110	COG1203	CRISPR-associated helicase, Cas3
M481_RS12135	COG0667	Aldo Keto reductase
M481_RS12145	COG0477	Major facilitator Superfamily
M481_RS12155	COG0583	DNA-binding transcription factor activity
M481_RS12160	COG2771	luxR family
M481_RS12165	COG3916	Acyl-homoserine-lactone synthase
M481_RS12195	COG0628	permease
M481_RS12210	COG3328	transposase activity
M481_RS12235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M481_RS12240	COG1530	ribonuclease E activity
M481_RS12245	COG0564	pseudouridine synthase activity
M481_RS12250	COG0424	maF-like protein
M481_RS12255	COG1399	metal-binding, possibly nucleic acid-binding protein
M481_RS12260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M481_RS12290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M481_RS12300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M481_RS12305	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M481_RS12315	COG0470	DNA polymerase III
M481_RS12320	COG0084	hydrolase, TatD family'
M481_RS12325	COG1263	PTS System
M481_RS12325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M481_RS12335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M481_RS12340	COG0537	adenosine 5'-monophosphoramidase activity
M481_RS12345	COG5633	Lipoprotein
M481_RS12360	COG1472	Belongs to the glycosyl hydrolase 3 family
M481_RS12370	COG1252	NADH dehydrogenase
M481_RS12385	COG3328	transposase activity
M481_RS12390	COG3134	Outer membrane lipoprotein
M481_RS12395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M481_RS12400	COG4591	ABC-type transport system involved in lipoprotein release permease component
M481_RS12410	COG4591	ABC-type transport system involved in lipoprotein release permease component
M481_RS12415	COG1940	carbohydrate kinase activity
M481_RS12430	COG2850	peptidyl-arginine hydroxylation
M481_RS12440	COG0745	RESPONSE REGULATOR receiver
M481_RS12450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M481_RS12470	COG1187	pseudouridine synthase activity
M481_RS12475	COG0538	isocitrate dehydrogenase activity
M481_RS12490	COG0840	transmembrane signaling receptor activity
M481_RS12495	COG0702	epimerase
M481_RS12500	COG1733	regulation of RNA biosynthetic process
M481_RS12525	COG1522	sequence-specific DNA binding
M481_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS12535	COG0604	alcohol dehydrogenase
M481_RS12535	COG3321	synthase
M481_RS12565	COG1285	pathogenesis
M481_RS12590	COG1360	Flagellar Motor Protein
M481_RS12595	COG0643	Histidine kinase
M481_RS12595	COG2198	Histidine kinase
M481_RS12600	COG0835	chemotaxis
M481_RS12605	COG2271	Major facilitator Superfamily
M481_RS12610	COG0251	oxidation-reduction process
M481_RS12620	COG2964	Protein conserved in bacteria
M481_RS12640	COG0840	transmembrane signaling receptor activity
M481_RS12645	COG0840	transmembrane signaling receptor activity
M481_RS12650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M481_RS12660	COG0745	RESPONSE REGULATOR receiver
M481_RS12665	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
M481_RS12675	COG3023	N-Acetylmuramoyl-L-alanine amidase
M481_RS12685	COG5295	Hep Hag repeat protein
M481_RS12695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M481_RS12750	COG3121	Chaperone
M481_RS12770	COG3008	intermembrane lipid transfer
M481_RS12775	COG2995	paraquat-inducible protein a
M481_RS12780	COG1956	GAF domain-containing protein
M481_RS12790	COG0793	Belongs to the peptidase S41A family
M481_RS12810	COG3539	Fimbrial protein
M481_RS12815	COG3121	Chaperone
M481_RS12830	COG3121	Chaperone
M481_RS12835	COG2814	Major facilitator Superfamily
M481_RS12840	COG0823	Involved in the tonB-independent uptake of proteins
M481_RS12850	COG3023	N-Acetylmuramoyl-L-alanine amidase
M481_RS12855	COG1823	symporter activity
M481_RS12860	COG1988	membrane-bound metal-dependent
M481_RS12865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M481_RS12870	COG1653	transport
M481_RS12875	COG3842	ATPase activity
M481_RS12880	COG0395	ABC-type sugar transport system, permease component
M481_RS12885	COG1175	transmembrane transport
M481_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS12905	COG1917	Cupin 2, conserved barrel domain protein
M481_RS12910	COG3328	transposase activity
M481_RS12915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M481_RS12925	COG3001	Fructosamine kinase
M481_RS12935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M481_RS12940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M481_RS12945	COG1121	(ABC) transporter
M481_RS12950	COG0803	Belongs to the bacterial solute-binding protein 9 family
M481_RS12975	COG4249	Peptidase C14 caspase catalytic subunit p20
M481_RS13005	COG0072	phenylalanine-tRNA ligase activity
M481_RS13005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M481_RS13010	COG0776	regulation of translation
M481_RS13025	COG0386	Belongs to the glutathione peroxidase family
M481_RS13070	COG0791	NLP P60 protein
M481_RS13095	COG0574	Belongs to the PEP-utilizing enzyme family
M481_RS13095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M481_RS13100	COG0628	permease
M481_RS13105	COG0247	lactate metabolic process
M481_RS13105	COG0277	FAD linked oxidase domain protein
M481_RS13110	COG2050	protein possibly involved in aromatic compounds catabolism
M481_RS13120	COG0316	Belongs to the HesB IscA family
M481_RS13125	COG0719	Fe-S assembly protein
M481_RS13130	COG0396	ATPase activity
M481_RS13135	COG0719	Fe-S assembly protein
M481_RS13150	COG1388	LysM domain
M481_RS13150	COG1376	ErfK ybiS ycfS ynhG family protein
M481_RS13200	COG0307	riboflavin synthase, alpha
M481_RS13205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M481_RS13210	COG2814	Major facilitator Superfamily
M481_RS13215	COG0583	DNA-binding transcription factor activity
M481_RS13230	COG0791	NLP P60 protein
M481_RS13240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M481_RS13250	COG0346	lactoylglutathione lyase activity
M481_RS13260	COG1902	pentaerythritol trinitrate reductase activity
M481_RS13265	COG1309	transcriptional regulator
M481_RS13270	COG2194	sulfuric ester hydrolase activity
M481_RS13275	COG3313	Fe-S protein
M481_RS13280	COG4989	oxidoreductase activity
M481_RS13290	COG3133	Outer membrane lipoprotein
M481_RS13300	COG3895	Periplasmic Protein
M481_RS13320	COG0625	glutathione transferase activity
M481_RS13335	COG3104	oligopeptide transport
M481_RS13340	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M481_RS13340	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M481_RS13345	COG4172	Belongs to the ABC transporter superfamily
M481_RS13355	COG4171	peptide transport system, permease
M481_RS13360	COG4168	peptide transport system, permease
M481_RS13365	COG4166	transmembrane transport
M481_RS13385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M481_RS13390	COG1842	Phage shock protein A
M481_RS13400	COG1983	PspC domain protein
M481_RS13410	COG3106	COG3106 Predicted ATPase
M481_RS13420	COG5654	RES domain protein
M481_RS13425	COG5642	Protein of unknown function (DUF2384)
M481_RS13450	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M481_RS13455	COG4948	Mandelate Racemase Muconate Lactonizing
M481_RS13460	COG2866	Carboxypeptidase
M481_RS13465	COG4166	transmembrane transport
M481_RS13485	COG0657	acetylesterase activity
M481_RS13495	COG1013	pyruvate-flavodoxin oxidoreductase activity
M481_RS13495	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M481_RS13495	COG0674	pyruvate-flavodoxin oxidoreductase activity
M481_RS13495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M481_RS13505	COG1285	pathogenesis
M481_RS13510	COG3042	response to heat
M481_RS13515	COG3187	Heat shock protein
M481_RS13520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M481_RS13525	COG2911	Protein conserved in bacteria
M481_RS13535	COG3784	Protein of unknown function (DUF1318)
M481_RS13540	COG0246	Mannitol dehydrogenase
M481_RS13545	COG2390	Transcriptional regulator
M481_RS13555	COG1643	Atp-dependent helicase
M481_RS13570	COG3591	Belongs to the peptidase S1B family
M481_RS13585	COG3038	cytochrome b561
M481_RS13620	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M481_RS13625	COG2205	protein histidine kinase activity
M481_RS13630	COG0745	RESPONSE REGULATOR receiver
M481_RS13640	COG0531	amino acid
M481_RS13655	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M481_RS13660	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
M481_RS13665	COG0589	response to stress
M481_RS13670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M481_RS13675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M481_RS13695	COG1011	Hydrolase
M481_RS13700	COG0440	acetolactate synthase activity
M481_RS13705	COG0028	Belongs to the TPP enzyme family
M481_RS13730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M481_RS13740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M481_RS13760	COG1609	Transcriptional regulator
M481_RS13775	COG0038	chloride channel
M481_RS13780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M481_RS13785	COG1940	carbohydrate kinase activity
M481_RS13790	COG0583	DNA-binding transcription factor activity
M481_RS13805	COG0114	fumarate hydratase activity
M481_RS13815	COG5339	Protein conserved in bacteria
M481_RS13825	COG0385	Bile acid
M481_RS13830	COG0673	inositol 2-dehydrogenase activity
M481_RS13845	COG1129	ABC transporter
M481_RS13850	COG1879	ABC-type sugar transport system periplasmic component
M481_RS13865	COG2274	protein secretion by the type I secretion system
M481_RS13870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M481_RS13880	COG1132	(ABC) transporter
M481_RS13910	COG3708	Transcriptional regulator
M481_RS13910	COG2207	Transcriptional regulator
M481_RS13915	COG4658	electron transport chain
M481_RS13920	COG4659	FMN binding
M481_RS13930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M481_RS13935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M481_RS13940	COG2271	Major facilitator Superfamily
M481_RS13950	COG1966	Carbon starvation protein
M481_RS13955	COG2879	small protein
M481_RS13960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M481_RS13980	COG0023	Translation Initiation Factor
M481_RS13995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
M481_RS14000	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
M481_RS14005	COG0671	phosphoesterase, PA-phosphatase related
M481_RS14015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M481_RS14025	COG0583	DNA-binding transcription factor activity
M481_RS14055	COG0616	signal peptide processing
M481_RS14060	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS14070	COG1187	pseudouridine synthase activity
M481_RS14075	COG0009	L-threonylcarbamoyladenylate synthase
M481_RS14100	COG0512	Glutamine amidotransferase of anthranilate synthase
M481_RS14110	COG0134	indole-3-glycerol-phosphate synthase activity
M481_RS14110	COG0135	phosphoribosylanthranilate isomerase activity
M481_RS14130	COG3047	cAMP biosynthetic process
M481_RS14165	COG3328	transposase activity
M481_RS14170	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
M481_RS14175	COG2350	Protein conserved in bacteria
M481_RS14210	COG4608	Belongs to the ABC transporter superfamily
M481_RS14215	COG0444	Belongs to the ABC transporter superfamily
M481_RS14220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M481_RS14225	COG0601	transmembrane transport
M481_RS14235	COG2095	MarC family integral membrane protein
M481_RS14240	COG1012	belongs to the aldehyde dehydrogenase family
M481_RS14240	COG1454	alcohol dehydrogenase
M481_RS14255	COG3328	transposase activity
M481_RS14265	COG0745	RESPONSE REGULATOR receiver
M481_RS14275	COG0788	formyltetrahydrofolate deformylase activity
M481_RS14285	COG3328	transposase activity
M481_RS14290	COG0583	DNA-binding transcription factor activity
M481_RS14295	COG0708	Exodeoxyribonuclease III
M481_RS14300	COG0494	nUDIX hydrolase
M481_RS14310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M481_RS14315	COG0709	Synthesizes selenophosphate from selenide and ATP
M481_RS14320	COG0778	Nitroreductase
M481_RS14325	COG0616	signal peptide processing
M481_RS14330	COG0252	asparaginase activity
M481_RS14335	COG1335	isochorismatase
M481_RS14340	COG3139	Protein of unknown function (DUF1315)
M481_RS14360	COG3713	MltA-interacting MipA family protein
M481_RS14365	COG2766	serine protein kinase
M481_RS14380	COG0583	DNA-binding transcription factor activity
M481_RS14390	COG2814	Major facilitator Superfamily
M481_RS14400	COG2719	SpoVR family
M481_RS14430	COG1104	cysteine desulfurase activity
M481_RS14700	COG0582	viral genome integration into host DNA
M481_RS14710	COG0179	Fumarylacetoacetate (FAA) hydrolase
M481_RS14715	COG2951	lytic endotransglycosylase activity
M481_RS14730	COG2894	cell division
M481_RS14735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
M481_RS14740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
M481_RS14745	COG0318	PFAM AMP-dependent synthetase and ligase
M481_RS14760	COG1199	ATP-dependent helicase activity
M481_RS14765	COG0251	oxidation-reduction process
M481_RS14780	COG0800	Aldolase
M481_RS14785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M481_RS14790	COG1737	Transcriptional regulator
M481_RS14795	COG0469	pyruvate kinase activity
M481_RS14800	COG1560	Kdo2-lipid A biosynthetic process
M481_RS14805	COG0739	heme binding
M481_RS14810	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
M481_RS14820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M481_RS14845	COG0494	nUDIX hydrolase
M481_RS14855	COG1801	Protein of unknown function DUF72
M481_RS14860	COG3788	relative of glutathione S-transferase, MAPEG superfamily
M481_RS14880	COG3102	Protein conserved in bacteria
M481_RS14900	COG0728	peptidoglycan biosynthetic process
M481_RS14905	COG0673	inositol 2-dehydrogenase activity
M481_RS14910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M481_RS14925	COG3381	protein complex oligomerization
M481_RS14940	COG1940	carbohydrate kinase activity
M481_RS14945	COG0584	glycerophosphoryl diester phosphodiesterase
M481_RS14950	COG3842	ATPase activity
M481_RS14965	COG1176	ABC-type spermidine putrescine transport system, permease component I
M481_RS14970	COG3833	ABC-type maltose transport systems, permease component
M481_RS14995	COG0659	secondary active sulfate transmembrane transporter activity
M481_RS15015	COG2890	protein-(glutamine-N5) methyltransferase activity
M481_RS15045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M481_RS15065	COG0012	GTP binding
M481_RS15115	COG0745	RESPONSE REGULATOR receiver
M481_RS15140	COG5002	protein histidine kinase activity
M481_RS15180	COG0500	methyltransferase
M481_RS15205	COG3328	transposase activity
M481_RS15250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M481_RS15255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M481_RS15260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M481_RS15275	COG0402	S-adenosylhomocysteine deaminase activity
M481_RS15310	COG3328	transposase activity
M481_RS15350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M481_RS15355	COG3850	Histidine kinase
M481_RS15360	COG0387	Pfam Sodium calcium exchanger
M481_RS15365	COG1702	phosphate starvation-inducible protein PhoH
M481_RS15380	COG3658	cytochrome
M481_RS15385	COG1215	transferase activity, transferring glycosyl groups
M481_RS15390	COG0726	polysaccharide deacetylase
M481_RS15390	COG1649	PFAM Uncharacterised BCR, COG1649
M481_RS15395	COG0457	Tetratricopeptide repeat
M481_RS15400	COG0006	proline dipeptidase activity
M481_RS15420	COG0577	efflux transmembrane transporter activity
M481_RS15420	COG1136	(ABC) transporter
M481_RS15430	COG0577	efflux transmembrane transporter activity
M481_RS15430	COG1136	(ABC) transporter
M481_RS15455	COG2066	Belongs to the glutaminase family
M481_RS15460	COG1349	DNA-binding transcription factor activity
M481_RS15470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M481_RS15475	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M481_RS15490	COG2814	Major facilitator Superfamily
M481_RS15515	COG2030	dehydratase
M481_RS15520	COG0427	acetyl-CoA hydrolase
M481_RS15530	COG2205	protein histidine kinase activity
M481_RS15530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS15545	COG3188	usher protein
M481_RS15555	COG3121	Chaperone
M481_RS15560	COG3328	transposase activity
M481_RS15575	COG0582	viral genome integration into host DNA
M481_RS15580	COG1169	isochorismate synthase
M481_RS15585	COG2814	Major facilitator Superfamily
M481_RS15590	COG1132	(ABC) transporter
M481_RS15605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M481_RS15605	COG3433	isochorismatase activity
M481_RS15605	COG2226	methyltransferase
M481_RS15625	COG1021	2,3-dihydroxybenzoate-AMP ligase
M481_RS15630	COG4771	TonB-dependent receptor
M481_RS15700	COG3842	ATPase activity
M481_RS15705	COG0395	ABC-type sugar transport system, permease component
M481_RS15710	COG1175	transmembrane transport
M481_RS15720	COG0673	inositol 2-dehydrogenase activity
M481_RS15730	COG2188	Transcriptional regulator
M481_RS15870	COG2197	response regulator
M481_RS15880	COG3136	membrane protein required for alginate biosynthesis
M481_RS15900	COG1113	amino acid transport
M481_RS15920	COG2822	iron ion transport
M481_RS15925	COG0672	)-iron permease
M481_RS15940	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M481_RS15940	COG0506	proline dehydrogenase activity
M481_RS15940	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M481_RS15955	COG1126	abc transporter atp-binding protein
M481_RS15960	COG0765	amino acid transport
M481_RS15980	COG1191	sigma factor activity
M481_RS16015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
M481_RS16020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M481_RS16035	COG1677	Flagellar hook-basal body complex protein FliE
M481_RS16055	COG1157	protein secretion by the type III secretion system
M481_RS16070	COG1580	Controls the rotational direction of flagella during chemotaxis
M481_RS16095	COG1987	bacterial-type flagellum assembly
M481_RS16115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M481_RS16120	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS16125	COG1129	ABC transporter
M481_RS16135	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS16140	COG3347	Dehydrogenase
M481_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS16145	COG2390	Transcriptional regulator
M481_RS16155	COG1256	bacterial-type flagellum assembly
M481_RS16195	COG1558	bacterial-type flagellum-dependent cell motility
M481_RS16200	COG1815	bacterial-type flagellum-dependent cell motility
M481_RS16210	COG2747	anti-sigma28 factor FlgM
M481_RS16215	COG3418	PFAM FlgN family protein
M481_RS16240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M481_RS16245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M481_RS16275	COG2372	response to copper ion
M481_RS16280	COG1528	Iron-storage protein
M481_RS16295	COG1770	oligopeptidase
M481_RS16310	COG3141	response to X-ray
M481_RS16315	COG0513	Belongs to the DEAD box helicase family
M481_RS16340	COG1760	l-serine dehydratase
M481_RS16345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M481_RS16350	COG2368	4-hydroxyphenylacetate
M481_RS16365	COG3971	2-oxopent-4-enoate hydratase activity
M481_RS16375	COG3384	dioxygenase
M481_RS16380	COG1012	belongs to the aldehyde dehydrogenase family
M481_RS16395	COG1846	Transcriptional regulator
M481_RS16405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M481_RS16405	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS16410	COG3715	PTS system
M481_RS16415	COG3716	PTS system mannose fructose sorbose family IID component
M481_RS16435	COG5002	protein histidine kinase activity
M481_RS16435	COG5001	Diguanylate cyclase
M481_RS16435	COG3447	MASE1 domain protein
M481_RS16445	COG2226	methyltransferase
M481_RS16450	COG1496	oxidoreductase activity
M481_RS16475	COG1113	amino acid transport
M481_RS16510	COG2207	Transcriptional regulator
M481_RS16520	COG1132	(ABC) transporter
M481_RS16560	COG2223	nitrite transmembrane transporter activity
M481_RS16580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M481_RS16605	COG3122	Protein conserved in bacteria
M481_RS16625	COG0534	Mate efflux family protein
M481_RS16640	COG4948	Mandelate Racemase Muconate Lactonizing
M481_RS16650	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS16655	COG3011	Protein conserved in bacteria
M481_RS16660	COG2271	Major facilitator Superfamily
M481_RS16665	COG1388	LysM domain
M481_RS16665	COG1470	cell adhesion involved in biofilm formation
M481_RS16685	COG2925	Exonuclease
M481_RS16690	COG0531	amino acid
M481_RS16700	COG0371	Dehydrogenase
M481_RS16710	COG1129	ABC transporter
M481_RS16715	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS16725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M481_RS16735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M481_RS16745	COG0131	Imidazoleglycerol-phosphate dehydratase
M481_RS16745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M481_RS16765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M481_RS16765	COG0140	phosphoribosyl-ATP diphosphatase activity
M481_RS16775	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M481_RS16780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M481_RS16795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M481_RS16800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M481_RS16805	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M481_RS16810	COG1120	ATPase activity
M481_RS16825	COG3486	L-lysine 6-monooxygenase (NADPH) activity
M481_RS16830	COG0076	glutamate decarboxylase activity
M481_RS16835	COG4114	ferric iron reductase
M481_RS16840	COG1253	flavin adenine dinucleotide binding
M481_RS16845	COG2982	Protein involved in outer membrane biogenesis
M481_RS16860	COG0489	protein tyrosine kinase activity
M481_RS16895	COG2814	Major facilitator Superfamily
M481_RS16905	COG1346	cytolysis
M481_RS16920	COG2949	membrane
M481_RS16940	COG4211	Belongs to the binding-protein-dependent transport system permease family
M481_RS16955	COG2311	Membrane
M481_RS16965	COG0477	Major facilitator Superfamily
M481_RS16970	COG0583	DNA-binding transcription factor activity
M481_RS17000	COG1136	(ABC) transporter
M481_RS17010	COG0303	'Molybdopterin
M481_RS17025	COG0488	(ABC) transporter
M481_RS17160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M481_RS17165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M481_RS17175	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS17180	COG1024	Enoyl-CoA hydratase
M481_RS17190	COG3425	synthase
M481_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS17200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M481_RS17205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M481_RS17215	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS17250	COG2920	part of a sulfur-relay system
M481_RS17270	COG1832	CoA-binding protein
M481_RS17285	COG0210	DNA helicase
M481_RS17290	COG3304	Inner membrane component domain
M481_RS17295	COG1289	transmembrane transporter activity
M481_RS17300	COG3070	regulator of competence-specific genes
M481_RS17330	COG1067	ATP-dependent peptidase activity
M481_RS17345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M481_RS17360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M481_RS17380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M481_RS17415	COG3086	response to oxidative stress
M481_RS17420	COG3026	antisigma factor binding
M481_RS17435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M481_RS17445	COG0513	Belongs to the DEAD box helicase family
M481_RS17495	COG1984	allophanate hydrolase subunit 2
M481_RS17505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M481_RS17510	COG5212	phosphodiesterase
M481_RS17520	COG3272	Protein of unknown function (DUF1722)
M481_RS17560	COG0745	RESPONSE REGULATOR receiver
M481_RS17580	COG0033	Phosphoglucomutase
M481_RS17585	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
M481_RS17605	COG2169	Transcriptional regulator
M481_RS17605	COG1917	Cupin 2, conserved barrel domain protein
M481_RS17610	COG1447	Phosphotransferase system cellobiose-specific component IIA
M481_RS17615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M481_RS17620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M481_RS17630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M481_RS17640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M481_RS17655	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
M481_RS17660	COG4413	Urea transporter
M481_RS17670	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
M481_RS17695	COG0831	urea catabolic process
M481_RS17700	COG1124	(ABC) transporter
M481_RS17705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
M481_RS17710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M481_RS17720	COG0747	negative chemotaxis
M481_RS17725	COG1278	Cold shock
M481_RS17765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M481_RS17770	COG4175	Glycine betaine
M481_RS17775	COG4176	ABC-type proline glycine betaine transport system permease component
M481_RS17780	COG2113	Glycine betaine
M481_RS17795	COG1953	Uracil, thiamine, allantoin
M481_RS17815	COG2226	methyltransferase
M481_RS17825	COG0741	lytic transglycosylase activity
M481_RS17825	COG1388	LysM domain
M481_RS17840	COG0656	L-ascorbic acid biosynthetic process
M481_RS17870	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M481_RS17880	COG2011	ABC-type metal ion transport system permease component
M481_RS17885	COG1464	Belongs to the NlpA lipoprotein family
M481_RS17895	COG1720	tRNA m6t6A37 methyltransferase activity
M481_RS17905	COG3015	lipoprotein NlpE involved in copper resistance
M481_RS17915	COG4681	YaeQ
M481_RS17925	COG4568	rho-dependent transcription termination
M481_RS17935	COG0037	tRNA processing
M481_RS17940	COG0346	lactoylglutathione lyase activity
M481_RS17950	COG0587	DNA-directed DNA polymerase activity
M481_RS17975	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M481_RS17990	COG0750	zinc metalloprotease
M481_RS17995	COG0575	Belongs to the CDS family
M481_RS18055	COG0564	pseudouridine synthase activity
M481_RS18060	COG3098	single-species biofilm formation
M481_RS18080	COG1611	Belongs to the LOG family
M481_RS18095	COG2363	Small membrane protein
M481_RS18100	COG0583	DNA-binding transcription factor activity
M481_RS18105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M481_RS18110	COG2166	iron-sulfur cluster assembly
M481_RS18115	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M481_RS18120	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
M481_RS18140	COG0860	N-Acetylmuramoyl-L-alanine amidase
M481_RS18145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M481_RS18145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M481_RS18165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M481_RS18170	COG1074	ATP-dependent DNA helicase activity
M481_RS18180	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M481_RS18245	COG0667	Aldo Keto reductase
M481_RS18275	COG1609	Transcriptional regulator
M481_RS18285	COG0583	DNA-binding transcription factor activity
M481_RS18290	COG2814	Major facilitator Superfamily
M481_RS18295	COG0583	DNA-binding transcription factor activity
M481_RS18310	COG0840	transmembrane signaling receptor activity
M481_RS18325	COG3328	transposase activity
M481_RS18390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M481_RS18410	COG0288	reversible hydration of carbon dioxide
M481_RS18455	COG3119	arylsulfatase activity
M481_RS18460	COG1349	DNA-binding transcription factor activity
M481_RS18470	COG2222	sugar isomerase
M481_RS18475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M481_RS18480	COG3715	PTS system
M481_RS18485	COG3716	PTS system mannose fructose sorbose family IID component
M481_RS18490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS18500	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS18510	COG0641	radical SAM
M481_RS18515	COG3119	arylsulfatase activity
M481_RS18545	COG2271	Major facilitator Superfamily
M481_RS18565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M481_RS18565	COG1263	PTS System
M481_RS18575	COG3867	Arabinogalactan endo-beta-1,4-galactanase
M481_RS18580	COG3833	ABC-type maltose transport systems, permease component
M481_RS18590	COG2182	Extracellular solute-binding protein
M481_RS18600	COG1129	ABC transporter
M481_RS18605	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS18610	COG1879	ABC-type sugar transport system periplasmic component
M481_RS18620	COG0791	NLP P60 protein
M481_RS18625	COG1695	Transcriptional regulator
M481_RS18720	COG2944	sequence-specific DNA binding
M481_RS18750	COG0582	viral genome integration into host DNA
M481_RS18770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M481_RS18775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M481_RS18780	COG4974	Belongs to the 'phage' integrase family
M481_RS18785	COG0716	FMN binding
M481_RS18790	COG4452	Inner membrane protein CreD
M481_RS18795	COG2205	protein histidine kinase activity
M481_RS18800	COG0745	RESPONSE REGULATOR receiver
M481_RS18825	COG1272	protein, Hemolysin III
M481_RS18835	COG5295	Hep Hag repeat protein
M481_RS18865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M481_RS18870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M481_RS18875	COG0006	proline dipeptidase activity
M481_RS18890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M481_RS18905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M481_RS18940	COG0191	fructose-bisphosphate aldolase activity
M481_RS18960	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M481_RS18965	COG0501	Belongs to the peptidase M48B family
M481_RS18975	COG1166	arginine decarboxylase activity
M481_RS18990	COG2356	endonuclease I
M481_RS18995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M481_RS19000	COG0189	ligase activity
M481_RS19015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M481_RS19025	COG2805	Type II/IV secretion system protein
M481_RS19030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M481_RS19035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M481_RS19040	COG0762	integral membrane protein
M481_RS19050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M481_RS19055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M481_RS19060	COG1073	alpha beta
M481_RS19060	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
M481_RS19060	COG3064	Membrane
M481_RS19080	COG3171	Protein conserved in bacteria
M481_RS19090	COG1194	a g-specific adenine glycosylase
M481_RS19110	COG4774	siderophore transport
M481_RS19115	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS19120	COG1129	ABC transporter
M481_RS19125	COG1879	ABC-type sugar transport system periplasmic component
M481_RS19130	COG1982	Orn Lys Arg decarboxylase major
M481_RS19235	COG3916	Acyl-homoserine-lactone synthase
M481_RS19240	COG2771	luxR family
M481_RS19290	COG2211	Major facilitator Superfamily
M481_RS19295	COG2801	Transposase and inactivated derivatives
M481_RS19310	COG3133	Outer membrane lipoprotein
M481_RS19340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M481_RS19345	COG1191	sigma factor activity
M481_RS19370	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M481_RS19380	COG3328	transposase activity
M481_RS19400	COG3710	Transcriptional regulator
M481_RS19420	COG1256	bacterial-type flagellum assembly
M481_RS19430	COG1706	bacterial-type flagellum-dependent cell motility
M481_RS19440	COG4786	Flagellar basal body rod
M481_RS19445	COG4787	bacterial-type flagellum-dependent cell motility
M481_RS19450	COG1749	Flagellar hook protein flgE
M481_RS19455	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M481_RS19460	COG1558	bacterial-type flagellum-dependent cell motility
M481_RS19465	COG1815	bacterial-type flagellum-dependent cell motility
M481_RS19470	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
M481_RS19510	COG1677	Flagellar hook-basal body complex protein FliE
M481_RS19535	COG1987	bacterial-type flagellum assembly
M481_RS19540	COG1684	flagellar biosynthetic protein fliR
M481_RS19545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M481_RS19565	COG4592	Periplasmic binding protein
M481_RS19600	COG4964	Belongs to the GSP D family
M481_RS19605	COG4964	Belongs to the GSP D family
M481_RS19655	COG0848	biopolymer transport protein
M481_RS19660	COG0811	peptide transport
M481_RS19665	COG0626	cystathionine gamma-synthase activity
M481_RS19670	COG0586	Pfam SNARE associated Golgi protein
M481_RS19675	COG2207	Transcriptional regulator
M481_RS19680	COG1979	alcohol dehydrogenase
M481_RS19690	COG0656	L-ascorbic acid biosynthetic process
M481_RS19700	COG2132	Multicopper oxidase
M481_RS19710	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M481_RS19720	COG2249	NAD(P)H dehydrogenase (quinone) activity
M481_RS19725	COG0583	DNA-binding transcription factor activity
M481_RS19735	COG3150	esterase
M481_RS19740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M481_RS19745	COG3151	Protein conserved in bacteria
M481_RS19750	COG0494	nUDIX hydrolase
M481_RS19755	COG1538	Outer membrane efflux protein
M481_RS19770	COG0754	glutathionylspermidine amidase activity
M481_RS19775	COG3384	dioxygenase
M481_RS19795	COG0531	amino acid
M481_RS19810	COG3025	triphosphatase activity
M481_RS19815	COG4991	sh3 domain protein
M481_RS19830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M481_RS19845	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M481_RS19850	COG0358	DNA primase activity
M481_RS19945	COG0251	oxidation-reduction process
M481_RS19965	COG0436	Aminotransferase
M481_RS19990	COG1289	transmembrane transporter activity
M481_RS20010	COG0395	ABC-type sugar transport system, permease component
M481_RS20020	COG2182	Extracellular solute-binding protein
M481_RS20025	COG1609	Transcriptional regulator
M481_RS20030	COG3459	Glycosyltransferase 36 associated
M481_RS20035	COG3842	ATPase activity
M481_RS20055	COG3210	domain, Protein
M481_RS20080	COG3210	domain, Protein
M481_RS20085	COG2831	hemolysin activation secretion protein
M481_RS20090	COG4245	von Willebrand factor, type A
M481_RS20125	COG3247	response to pH
M481_RS20130	COG0446	pyridine nucleotide-disulphide oxidoreductase
M481_RS20130	COG1902	pentaerythritol trinitrate reductase activity
M481_RS20145	COG1451	nucleotide metabolic process
M481_RS20150	COG0673	inositol 2-dehydrogenase activity
M481_RS20170	COG2721	sulfolactate sulfo-lyase activity
M481_RS20205	COG0586	Pfam SNARE associated Golgi protein
M481_RS20225	COG4575	ribosome binding
M481_RS20230	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
M481_RS20240	COG2259	Doxx family
M481_RS20245	COG0435	Glutathione S-transferase
M481_RS20250	COG0583	DNA-binding transcription factor activity
M481_RS20255	COG1741	Belongs to the pirin family
M481_RS20260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M481_RS20280	COG2823	Periplasmic or secreted lipoprotein
M481_RS20300	COG5002	protein histidine kinase activity
M481_RS20300	COG2198	Histidine kinase
M481_RS20300	COG0784	Response regulator, receiver
M481_RS20310	COG1242	4 iron, 4 sulfur cluster binding
M481_RS20315	COG0069	glutamate synthase activity
M481_RS20315	COG0070	glutamate synthase
M481_RS20315	COG0067	glutamate synthase
M481_RS20320	COG0493	'glutamate synthase
M481_RS20330	COG2969	positive regulation of protein catabolic process
M481_RS20335	COG0625	glutathione transferase activity
M481_RS20355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M481_RS20360	COG3105	Protein conserved in bacteria
M481_RS20365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M481_RS20375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M481_RS20385	COG5007	Belongs to the BolA IbaG family
M481_RS20390	COG3113	response to antibiotic
M481_RS20395	COG2854	intermembrane phospholipid transfer
M481_RS20400	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M481_RS20405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M481_RS20410	COG1127	ABC transporter
M481_RS20415	COG0530	calcium, potassium:sodium antiporter activity
M481_RS20420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M481_RS20420	COG0517	IMP dehydrogenase activity
M481_RS20425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M481_RS20430	COG3117	lipopolysaccharide transmembrane transporter activity
M481_RS20435	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M481_RS20440	COG1137	ATPase activity
M481_RS20445	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M481_RS20465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M481_RS20490	COG1609	Transcriptional regulator
M481_RS20495	COG1263	PTS System
M481_RS20495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M481_RS20500	COG0366	Alpha amylase catalytic
M481_RS20505	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M481_RS20510	COG3783	Cytochrome b(562)
M481_RS20520	COG0312	modulator of DNA gyrase
M481_RS20530	COG2732	(Barnase) inhibitor
M481_RS20545	COG1012	belongs to the aldehyde dehydrogenase family
M481_RS20565	COG0583	DNA-binding transcription factor activity
M481_RS20615	COG0312	modulator of DNA gyrase
M481_RS20620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M481_RS20625	COG3164	Protein of unknown function
M481_RS20630	COG1530	ribonuclease E activity
M481_RS20635	COG0424	maF-like protein
M481_RS20640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M481_RS20645	COG1792	Involved in formation and maintenance of cell shape
M481_RS20650	COG1077	Cell shape determining protein MreB Mrl
M481_RS20655	COG2199	diguanylate cyclase activity
M481_RS20655	COG2200	EAL domain
M481_RS20660	COG0604	alcohol dehydrogenase
M481_RS20665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M481_RS20680	COG0511	ligase activity, forming carbon-carbon bonds
M481_RS20685	COG0439	Biotin carboxylase
M481_RS20690	COG3924	membrane
M481_RS20695	COG4145	pantothenate transmembrane transporter activity
M481_RS20705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M481_RS20710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M481_RS20730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M481_RS20740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M481_RS20745	COG3133	Outer membrane lipoprotein
M481_RS20755	COG1278	Cold shock
M481_RS20760	COG1278	Cold shock
M481_RS20785	COG0625	glutathione transferase activity
M481_RS20795	COG1069	ribulokinase activity
M481_RS20805	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS20810	COG1129	ABC transporter
M481_RS20820	COG1560	Kdo2-lipid A biosynthetic process
M481_RS20830	COG0025	NhaP-type Na H and K H
M481_RS20835	COG2252	PERMEase
M481_RS20840	COG3077	Addiction module antitoxin, RelB DinJ family
M481_RS20850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M481_RS20860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M481_RS20865	COG0431	NADPH-dependent FMN reductase
M481_RS20870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M481_RS20875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M481_RS20880	COG1869	D-ribose catabolic process
M481_RS20885	COG1917	Cupin 2, conserved barrel domain protein
M481_RS20885	COG2207	Transcriptional regulator
M481_RS20890	COG0673	inositol 2-dehydrogenase activity
M481_RS20905	COG3209	COG3209 Rhs family protein
M481_RS20915	COG3501	Rhs element vgr protein
M481_RS20955	COG3501	Rhs element vgr protein
M481_RS21030	COG2801	Transposase and inactivated derivatives
M481_RS21090	COG1175	transmembrane transport
M481_RS21095	COG3833	ABC-type maltose transport systems, permease component
M481_RS21110	COG0527	aspartate kinase activity
M481_RS21130	COG1414	Transcriptional regulator
M481_RS21140	COG2224	Isocitrate lyase
M481_RS21145	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M481_RS21195	COG0542	response to heat
M481_RS21205	COG0564	pseudouridine synthase activity
M481_RS21210	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M481_RS21215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M481_RS21230	COG1605	Chorismate mutase
M481_RS21230	COG0077	Prephenate dehydratase
M481_RS21235	COG1605	Chorismate mutase
M481_RS21235	COG0287	Prephenate dehydrogenase
M481_RS21240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M481_RS21285	COG1459	type II secretion system
M481_RS21290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M481_RS21295	COG4969	Belongs to the N-Me-Phe pilin family
M481_RS21305	COG3023	N-Acetylmuramoyl-L-alanine amidase
M481_RS21310	COG3725	Membrane protein required for beta-lactamase induction
M481_RS21315	COG1113	amino acid transport
M481_RS21320	COG2186	Transcriptional regulator
M481_RS21325	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
M481_RS21330	COG0508	dehydrogenase complex catalyzes the overall conversion of
M481_RS21335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M481_RS21350	COG1049	propionate catabolic process, 2-methylcitrate cycle
M481_RS21360	COG0697	spore germination
M481_RS21380	COG2132	Multicopper oxidase
M481_RS21385	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M481_RS21390	COG0288	reversible hydration of carbon dioxide
M481_RS21395	COG1131	(ABC) transporter
M481_RS21400	COG0842	Transport permease protein
M481_RS21425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M481_RS21430	COG0617	tRNA 3'-terminal CCA addition
M481_RS21435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M481_RS21450	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M481_RS21455	COG1643	Atp-dependent helicase
M481_RS21460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M481_RS21470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M481_RS21475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M481_RS21495	COG2860	membrane
M481_RS21515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M481_RS21520	COG2205	protein histidine kinase activity
M481_RS21520	COG3437	response regulator, receiver
M481_RS21520	COG3850	Histidine kinase
M481_RS21520	COG4999	Histidine kinase
M481_RS21525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M481_RS21535	COG3956	TIGRFAM MazG family protein
M481_RS21555	COG0602	queuosine metabolic process
M481_RS21560	COG0720	synthase
M481_RS21610	COG0529	Catalyzes the synthesis of activated sulfate
M481_RS21650	COG4942	peptidase
M481_RS21650	COG1388	LysM domain
M481_RS21655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M481_RS21670	COG0698	ribose 5-phosphate isomerase
M481_RS21675	COG1063	alcohol dehydrogenase
M481_RS21680	COG1028	Short-chain dehydrogenase reductase Sdr
M481_RS21685	COG2376	Dihydroxyacetone kinase
M481_RS21700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M481_RS21720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M481_RS21725	COG1858	cytochrome C peroxidase
M481_RS21735	COG4771	TonB-dependent receptor
M481_RS21760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M481_RS21760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M481_RS21765	COG1070	Carbohydrate kinase
M481_RS21770	COG3623	hexulose-6-phosphate isomerase
M481_RS21775	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS21780	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS21785	COG1129	ABC transporter
M481_RS21795	COG1349	DNA-binding transcription factor activity
M481_RS21800	COG0235	Class ii aldolase
M481_RS21805	COG0243	molybdopterin cofactor binding
M481_RS21810	COG0437	4 iron, 4 sulfur cluster binding
M481_RS21815	COG3302	dmso reductase anchor subunit
M481_RS21820	COG3381	protein complex oligomerization
M481_RS21825	COG3038	cytochrome b561
M481_RS21830	COG3783	Cytochrome b(562)
M481_RS21840	COG1879	ABC-type sugar transport system periplasmic component
M481_RS21850	COG1129	ABC transporter
M481_RS21855	COG1172	Belongs to the binding-protein-dependent transport system permease family
M481_RS21860	COG3959	Transketolase, thiamine diphosphate binding domain
M481_RS21865	COG3958	Transketolase
M481_RS21870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M481_RS21915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
M481_RS21935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M481_RS21940	COG1238	metal cluster binding
M481_RS21945	COG2918	glutathione biosynthetic process
M481_RS21955	COG4536	flavin adenine dinucleotide binding
M481_RS21960	COG4137	Cytochrome C assembly protein
M481_RS21965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M481_RS21990	COG3137	Salt-induced outer membrane protein
M481_RS22000	COG3279	Response regulator of the LytR AlgR family
M481_RS22005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M481_RS22020	COG0494	nUDIX hydrolase