locus-tag	class	description
M483_RS00405	COG2814	Major facilitator Superfamily
M483_RS00735	COG1278	Cold shock
M483_RS00950	COG0517	IMP dehydrogenase activity
M483_RS00950	COG0516	GMP reductase activity
M483_RS01090	COG3468	outer membrane autotransporter barrel domain protein
M483_RS01165	COG1104	cysteine desulfurase activity
M483_RS01230	COG3842	ATPase activity
M483_RS01255	COG2205	protein histidine kinase activity
M483_RS01260	COG0745	RESPONSE REGULATOR receiver
M483_RS01265	COG3422	double-strand break repair
M483_RS01270	COG0826	peptidase U32
M483_RS01290	COG0351	phosphomethylpyrimidine kinase
M483_RS01305	COG3328	transposase activity
M483_RS01360	COG0516	GMP reductase activity
M483_RS01360	COG0517	IMP dehydrogenase activity
M483_RS01370	COG1645	bacterial-type flagellum-dependent swarming motility
M483_RS01385	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M483_RS01390	COG2976	Protein conserved in bacteria
M483_RS01435	COG3468	outer membrane autotransporter barrel domain protein
M483_RS01440	COG3468	outer membrane autotransporter barrel domain protein
M483_RS01460	COG2975	iron-sulfur cluster assembly
M483_RS01465	COG0633	Ferredoxin
M483_RS01470	COG0443	Heat shock 70 kDa protein
M483_RS01485	COG0822	iron-sulfur transferase activity
M483_RS01490	COG1104	cysteine desulfurase activity
M483_RS01510	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
M483_RS01515	COG3683	transport system, periplasmic component
M483_RS01520	COG3711	transcriptional antiterminator
M483_RS01525	COG2814	Major facilitator Superfamily
M483_RS01545	COG1017	nitric oxide dioxygenase activity
M483_RS01545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M483_RS01560	COG2188	Transcriptional regulator
M483_RS01565	COG0347	Belongs to the P(II) protein family
M483_RS01570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M483_RS01570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M483_RS01575	COG2204	response regulator
M483_RS01580	COG3170	Tfp pilus assembly protein FimV
M483_RS01585	COG2205	protein histidine kinase activity
M483_RS01625	COG0560	Phosphoserine phosphatase
M483_RS01635	COG1737	Transcriptional regulator
M483_RS01640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M483_RS01655	COG3130	regulation of translation
M483_RS01665	COG3009	Protein conserved in bacteria
M483_RS01670	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M483_RS01670	COG3008	intermembrane lipid transfer
M483_RS01675	COG2995	paraquat-inducible protein a
M483_RS01680	COG0488	(ABC) transporter
M483_RS01690	COG0633	Ferredoxin
M483_RS01690	COG3217	Mosc domain protein beta barrel domain protein
M483_RS01705	COG0308	aminopeptidase N
M483_RS01725	COG1448	Aminotransferase
M483_RS01730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M483_RS01735	COG3108	Peptidase M15
M483_RS01740	COG2989	Protein conserved in bacteria
M483_RS01770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M483_RS01780	COG3173	Aminoglycoside phosphotransferase
M483_RS01795	COG1278	Cold shock
M483_RS01805	COG5383	Protein conserved in bacteria
M483_RS01820	COG0658	competence protein
M483_RS01820	COG2333	competence protein COMEC
M483_RS01835	COG0539	negative regulation of cytoplasmic translation
M483_RS01860	COG5295	Hep Hag repeat protein
M483_RS01860	COG5295	Hep Hag repeat protein
M483_RS01865	COG0252	asparaginase activity
M483_RS01870	COG1944	ATP diphosphatase activity
M483_RS01875	COG2116	formate transmembrane transporter activity
M483_RS01880	COG1882	Formate acetyltransferase
M483_RS01890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M483_RS01905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M483_RS01915	COG1674	ftsk spoiiie
M483_RS01915	COG3107	peptidoglycan biosynthetic process
M483_RS01925	COG0492	ferredoxin-NADP+ reductase activity
M483_RS01940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M483_RS01950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M483_RS01960	COG0542	response to heat
M483_RS01970	COG1278	Cold shock
M483_RS01980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M483_RS01985	COG2990	Protein conserved in bacteria
M483_RS01990	COG3593	DNA synthesis involved in DNA repair
M483_RS01995	COG2431	L-lysine efflux transmembrane transporter activity
M483_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M483_RS02010	COG0028	Belongs to the TPP enzyme family
M483_RS02015	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
M483_RS02020	COG0702	epimerase
M483_RS02025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M483_RS02035	COG1605	Chorismate mutase
M483_RS02040	COG1126	abc transporter atp-binding protein
M483_RS02045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M483_RS02050	COG4215	(ABC) transporter
M483_RS02055	COG4160	amino acid transport
M483_RS02075	COG1120	ATPase activity
M483_RS02110	COG1177	transmembrane transport
M483_RS02115	COG1176	ABC-type spermidine putrescine transport system, permease component I
M483_RS02120	COG3842	ATPase activity
M483_RS02125	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M483_RS02160	COG0671	phosphoesterase, PA-phosphatase related
M483_RS02170	COG1349	DNA-binding transcription factor activity
M483_RS02175	COG0814	amino acid
M483_RS02185	COG1686	Belongs to the peptidase S11 family
M483_RS02190	COG2011	ABC-type metal ion transport system permease component
M483_RS02215	COG0625	glutathione transferase activity
M483_RS02220	COG4771	TonB-dependent receptor
M483_RS02230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M483_RS02245	COG0833	amino acid
M483_RS02250	COG0583	DNA-binding transcription factor activity
M483_RS02255	COG2855	membrane
M483_RS02265	COG3188	usher protein
M483_RS02270	COG3121	Chaperone
M483_RS02285	COG3710	Transcriptional regulator
M483_RS02290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M483_RS02290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M483_RS02290	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M483_RS02295	COG1105	Belongs to the carbohydrate kinase PfkB family
M483_RS02305	COG0494	nUDIX hydrolase
M483_RS02315	COG1129	ABC transporter
M483_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS02375	COG0246	Mannitol dehydrogenase
M483_RS02390	COG0523	cobalamin synthesis protein
M483_RS02395	COG0671	phosphoesterase, PA-phosphatase related
M483_RS02400	COG0791	NLP P60 protein
M483_RS02405	COG2200	EAL domain
M483_RS02410	COG4166	transmembrane transport
M483_RS02415	COG4174	ABC transporter (Permease)
M483_RS02420	COG4239	(ABC) transporter, permease
M483_RS02425	COG4172	Belongs to the ABC transporter superfamily
M483_RS02435	COG2814	Major facilitator Superfamily
M483_RS02440	COG1187	pseudouridine synthase activity
M483_RS02445	COG1061	Type III restriction enzyme res subunit
M483_RS02465	COG3082	Protein of unknown function (DUF1414)
M483_RS02470	COG3083	sulfuric ester hydrolase activity
M483_RS02480	COG3157	Type VI secretion system effector, Hcp
M483_RS02495	COG2723	6-phospho-beta-galactosidase activity
M483_RS02500	COG1737	Transcriptional regulator
M483_RS02520	COG3299	homolog of phage Mu protein gp47
M483_RS02560	COG4386	tail sheath protein
M483_RS02580	COG3622	Belongs to the hyi family
M483_RS02585	COG1349	DNA-binding transcription factor activity
M483_RS02590	COG0235	Class ii aldolase
M483_RS02595	COG3395	kinase activity
M483_RS02640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M483_RS02665	COG2198	Histidine kinase
M483_RS02665	COG0642	Histidine kinase
M483_RS02670	COG0642	Histidine kinase
M483_RS02670	COG2198	Histidine kinase
M483_RS02680	COG2205	protein histidine kinase activity
M483_RS02680	COG0784	Response regulator, receiver
M483_RS02710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M483_RS02725	COG0814	amino acid
M483_RS02750	COG0697	spore germination
M483_RS02760	COG1982	Orn Lys Arg decarboxylase major
M483_RS02765	COG3328	transposase activity
M483_RS02770	COG1982	Orn Lys Arg decarboxylase major
M483_RS02775	COG0531	amino acid
M483_RS02780	COG1174	glycine betaine transport
M483_RS02785	COG1125	glycine betaine transport
M483_RS02790	COG1174	glycine betaine transport
M483_RS02795	COG1732	Glycine betaine
M483_RS02800	COG2897	thiosulfate sulfurtransferase activity
M483_RS02820	COG1122	ATPase activity
M483_RS02840	COG4807	Protein conserved in bacteria
M483_RS02855	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
M483_RS02865	COG2261	transglycosylase associated protein
M483_RS02885	COG0277	FAD linked oxidase domain protein
M483_RS02890	COG1686	Belongs to the peptidase S11 family
M483_RS02900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M483_RS02925	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M483_RS02935	COG0583	DNA-binding transcription factor activity
M483_RS02940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M483_RS02970	COG0670	Belongs to the BI1 family
M483_RS02975	COG0314	molybdopterin synthase activity
M483_RS02980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M483_RS02990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M483_RS03000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M483_RS03005	COG4628	conserved protein (DUF2132)
M483_RS03015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M483_RS03025	COG2226	methyltransferase
M483_RS03050	COG0561	phosphatase activity
M483_RS03060	COG4149	molybdate abc transporter
M483_RS03065	COG0725	ABC transporter, periplasmic molybdate-binding protein
M483_RS03075	COG2005	Transcriptional regulator
M483_RS03075	COG3585	molybdate ion transport
M483_RS03080	COG1119	ATPase activity
M483_RS03095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M483_RS03100	COG1085	galactose-1-phosphate uridylyltransferase
M483_RS03115	COG2017	converts alpha-aldose to the beta-anomer
M483_RS03135	COG1230	cation diffusion facilitator family transporter
M483_RS03170	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
M483_RS03175	COG2885	chlorophyll binding
M483_RS03185	COG3064	Membrane
M483_RS03185	COG3064	Membrane
M483_RS03190	COG0848	biopolymer transport protein
M483_RS03195	COG0811	peptide transport
M483_RS03200	COG0824	Thioesterase
M483_RS03205	COG3790	cyd operon protein YbgE
M483_RS03210	COG4890	Cyd operon protein YbgT
M483_RS03215	COG1294	oxidase, subunit
M483_RS03220	COG1271	oxidase subunit
M483_RS03230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M483_RS03240	COG0508	dehydrogenase complex catalyzes the overall conversion of
M483_RS03245	COG0567	Dehydrogenase, E1 component
M483_RS03255	COG1053	succinate dehydrogenase
M483_RS03260	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M483_RS03265	COG2009	succinate dehydrogenase
M483_RS03280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M483_RS03285	COG0497	DNA recombination
M483_RS03290	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M483_RS03300	COG2867	negative regulation of translational initiation
M483_RS03320	COG0582	viral genome integration into host DNA
M483_RS03380	COG3657	addiction module killer protein
M483_RS03400	COG0582	viral genome integration into host DNA
M483_RS03405	COG2963	transposase activity
M483_RS03410	COG0582	viral genome integration into host DNA
M483_RS03420	COG0596	Alpha beta hydrolase
M483_RS03440	COG0735	belongs to the Fur family
M483_RS03460	COG1263	PTS System
M483_RS03460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M483_RS03460	COG2190	(PTS) system
M483_RS03470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M483_RS03475	COG1846	Transcriptional regulator
M483_RS03475	COG1940	carbohydrate kinase activity
M483_RS03480	COG0647	UMP catabolic process
M483_RS03485	COG0367	asparagine synthase
M483_RS03525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M483_RS03535	COG1702	phosphate starvation-inducible protein PhoH
M483_RS03545	COG4535	Mg2 and Co2 transporter CorC
M483_RS03550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
M483_RS03560	COG0765	amino acid transport
M483_RS03565	COG0765	amino acid transport
M483_RS03570	COG1126	abc transporter atp-binding protein
M483_RS03575	COG2888	peptidyl-tyrosine sulfation
M483_RS03590	COG1466	dna polymerase III delta subunit
M483_RS03600	COG0799	negative regulation of ribosome biogenesis
M483_RS03610	COG0768	penicillin binding
M483_RS03615	COG0772	Belongs to the SEDS family
M483_RS03620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M483_RS03625	COG1686	Belongs to the peptidase S11 family
M483_RS03645	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M483_RS03655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M483_RS03665	COG1278	Cold shock
M483_RS03670	COG2197	response regulator
M483_RS03695	COG5265	(ABC) transporter
M483_RS03705	COG3718	enzyme involved in inositol metabolism
M483_RS03715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M483_RS03720	COG0673	inositol 2-dehydrogenase activity
M483_RS03725	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS03730	COG1129	ABC transporter
M483_RS03765	COG2373	Large extracellular alpha-helical protein
M483_RS03770	COG4953	penicillin-binding protein 1C
M483_RS03775	COG3423	Transcriptional regulator
M483_RS03825	COG2850	peptidyl-arginine hydroxylation
M483_RS03830	COG3328	transposase activity
M483_RS03845	COG1472	Belongs to the glycosyl hydrolase 3 family
M483_RS03865	COG0656	L-ascorbic acid biosynthetic process
M483_RS03870	COG0667	Aldo Keto reductase
M483_RS03900	COG2453	phosphatase
M483_RS03900	COG0671	phosphoesterase, PA-phosphatase related
M483_RS03905	COG2267	carboxylic ester hydrolase activity
M483_RS03915	COG4589	Belongs to the CDS family
M483_RS03920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M483_RS03965	COG2501	S4 domain
M483_RS03985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M483_RS03995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M483_RS04000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M483_RS04005	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M483_RS04010	COG4181	ATPase activity
M483_RS04015	COG2755	lipolytic protein G-D-S-L family
M483_RS04020	COG0300	oxidoreductase activity
M483_RS04025	COG3118	belongs to the thioredoxin family
M483_RS04030	COG0330	HflC and HflK could
M483_RS04035	COG1585	Membrane protein implicated in regulation of membrane protease activity
M483_RS04040	COG0789	Transcriptional regulator
M483_RS04045	COG2217	Heavy metal translocating P-type atpase
M483_RS04050	COG3735	TraB family
M483_RS04055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M483_RS04070	COG0737	Belongs to the 5'-nucleotidase family
M483_RS04075	COG0737	Belongs to the 5'-nucleotidase family
M483_RS04080	COG0737	Belongs to the 5'-nucleotidase family
M483_RS04090	COG4651	solute:proton antiporter activity
M483_RS04090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M483_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M483_RS04100	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M483_RS04120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M483_RS04160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M483_RS04185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M483_RS04185	COG0543	2 iron, 2 sulfur cluster binding
M483_RS04215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M483_RS04240	COG3264	Mechanosensitive ion channel
M483_RS04240	COG1196	nuclear chromosome segregation
M483_RS04245	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M483_RS04250	COG1309	transcriptional regulator
M483_RS04255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M483_RS04260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M483_RS04270	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M483_RS04290	COG3695	enzyme binding
M483_RS04295	COG3126	Type III secretion system lipoprotein chaperone (YscW)
M483_RS04300	COG1946	Acyl-CoA thioesterase
M483_RS04305	COG0004	ammonium transporteR
M483_RS04310	COG0347	Belongs to the P(II) protein family
M483_RS04315	COG1132	(ABC) transporter
M483_RS04320	COG1132	(ABC) transporter
M483_RS04325	COG1522	sequence-specific DNA binding
M483_RS04340	COG4533	DNA binding
M483_RS04350	COG0824	Thioesterase
M483_RS04355	COG1555	photosystem II stabilization
M483_RS04360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M483_RS04375	COG0776	regulation of translation
M483_RS04380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M483_RS04405	COG0271	Belongs to the BolA IbaG family
M483_RS04410	COG3056	Lipoprotein
M483_RS04415	COG2223	nitrite transmembrane transporter activity
M483_RS04425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M483_RS04430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M483_RS04435	COG1845	cytochrome c oxidase, subunit III
M483_RS04440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M483_RS04450	COG2814	Major facilitator Superfamily
M483_RS04460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M483_RS04465	COG0693	protein deglycase activity
M483_RS04485	COG0142	geranyltranstransferase activity
M483_RS04500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M483_RS04505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M483_RS04520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M483_RS04520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M483_RS04545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M483_RS04550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M483_RS04555	COG1862	Preprotein translocase
M483_RS04575	COG0450	alkyl hydroperoxide reductase
M483_RS04595	COG0366	Alpha amylase catalytic
M483_RS04620	COG0745	RESPONSE REGULATOR receiver
M483_RS04630	COG0420	3'-5' exonuclease activity
M483_RS04635	COG0419	ATPase involved in DNA repair
M483_RS04640	COG1940	carbohydrate kinase activity
M483_RS04675	COG2226	methyltransferase
M483_RS04735	COG2195	Cleaves the N-terminal amino acid of tripeptides
M483_RS04755	COG1477	protein flavinylation
M483_RS04775	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M483_RS04780	COG1805	sodium ion transport
M483_RS04790	COG3034	peptidoglycan biosynthetic process
M483_RS04795	COG0121	glutamine amidotransferase
M483_RS04805	COG1960	acyl-CoA dehydrogenase activity
M483_RS04820	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
M483_RS04860	COG0436	Aminotransferase
M483_RS04875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M483_RS04890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M483_RS04900	COG0765	amino acid transport
M483_RS04940	COG2814	Major facilitator Superfamily
M483_RS04945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M483_RS04955	COG1846	Transcriptional regulator
M483_RS04960	COG1566	PFAM secretion protein HlyD family protein
M483_RS04965	COG2814	Major facilitator Superfamily
M483_RS04970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M483_RS04975	COG3118	belongs to the thioredoxin family
M483_RS04980	COG3148	PFAM DTW domain containing protein
M483_RS04985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M483_RS04985	COG1042	CoA-binding domain protein
M483_RS04985	COG0045	succinate-CoA ligase (ADP-forming) activity
M483_RS04990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M483_RS04995	COG5544	Lipoprotein
M483_RS05065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M483_RS05065	COG0678	peroxiredoxin activity
M483_RS05070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M483_RS05095	COG1629	transport
M483_RS05115	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M483_RS05135	COG2801	Transposase and inactivated derivatives
M483_RS05160	COG0195	Participates in both transcription termination and antitermination
M483_RS05180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M483_RS05190	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M483_RS05205	COG1534	Rna-binding protein
M483_RS05215	COG2027	D-alanyl-D-alanine carboxypeptidase
M483_RS05220	COG0745	RESPONSE REGULATOR receiver
M483_RS05225	COG0642	Histidine kinase
M483_RS05235	COG0697	spore germination
M483_RS05250	COG0142	geranyltranstransferase activity
M483_RS05260	COG3423	Transcriptional regulator
M483_RS05285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M483_RS05295	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M483_RS05300	COG2105	PFAM AIG2 family protein
M483_RS05305	COG2911	Protein conserved in bacteria
M483_RS05310	COG0729	surface antigen
M483_RS05320	COG1253	flavin adenine dinucleotide binding
M483_RS05330	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
M483_RS05340	COG0737	Belongs to the 5'-nucleotidase family
M483_RS05350	COG0545	Peptidyl-prolyl cis-trans isomerase
M483_RS05355	COG3061	Opacity-associated protein A
M483_RS05380	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M483_RS05400	COG1073	alpha beta
M483_RS05430	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M483_RS05455	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
M483_RS05460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M483_RS05465	COG1739	Uncharacterized protein family UPF0029
M483_RS05490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
M483_RS05510	COG0805	protein transport
M483_RS05520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M483_RS05540	COG1322	Protein conserved in bacteria
M483_RS05545	COG0586	Pfam SNARE associated Golgi protein
M483_RS05550	COG1966	Carbon starvation protein
M483_RS05565	COG0412	Dienelactone hydrolase
M483_RS05575	COG0583	DNA-binding transcription factor activity
M483_RS05580	COG0697	spore germination
M483_RS05585	COG0679	Auxin Efflux Carrier
M483_RS05590	COG0584	glycerophosphoryl diester phosphodiesterase
M483_RS05650	COG0410	ABC transporter
M483_RS05660	COG4177	L-phenylalanine transmembrane transporter activity
M483_RS05670	COG0683	leucine binding
M483_RS05695	COG2177	Part of the ABC transporter FtsEX involved in
M483_RS05700	COG2884	Cell division ATP-binding protein ftsE
M483_RS05705	COG0552	protein localization to endoplasmic reticulum
M483_RS05705	COG0552	protein localization to endoplasmic reticulum
M483_RS05715	COG0742	ribosomal rna small subunit methyltransferase
M483_RS05720	COG3776	membrane
M483_RS05735	COG3714	YhhN family
M483_RS05750	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M483_RS05760	COG0247	lactate metabolic process
M483_RS05770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M483_RS05780	COG0584	glycerophosphoryl diester phosphodiesterase
M483_RS05790	COG0561	phosphatase activity
M483_RS05795	COG2267	carboxylic ester hydrolase activity
M483_RS05800	COG1280	lysine exporter protein (LysE YggA)
M483_RS05805	COG1280	lysine exporter protein (LysE YggA)
M483_RS05810	COG0514	ATP-dependent DNA helicase (RecQ)
M483_RS05815	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
M483_RS05820	COG2050	protein possibly involved in aromatic compounds catabolism
M483_RS05835	COG5564	TIM-barrel signal transduction protein
M483_RS05840	COG5441	Belongs to the UPF0261 family
M483_RS05850	COG0210	DNA helicase
M483_RS05855	COG1011	Hydrolase
M483_RS05860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M483_RS05865	COG3159	Protein conserved in bacteria
M483_RS05885	COG3072	Adenylate cyclase
M483_RS05895	COG1587	Uroporphyrinogen-III synthase
M483_RS05900	COG2959	enzyme of heme biosynthesis
M483_RS05905	COG3071	HemY protein
M483_RS05935	COG1113	amino acid transport
M483_RS05955	COG2244	polysaccharide biosynthetic process
M483_RS05960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M483_RS05965	COG0456	acetyltransferase
M483_RS05970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M483_RS05975	COG1088	dTDP-glucose 4,6-dehydratase activity
M483_RS05980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M483_RS05985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M483_RS05990	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
M483_RS05995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M483_RS06000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M483_RS06005	COG3118	belongs to the thioredoxin family
M483_RS06030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M483_RS06050	COG3121	Chaperone
M483_RS06065	COG3121	Chaperone
M483_RS06105	COG0583	DNA-binding transcription factor activity
M483_RS06145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M483_RS06150	COG3978	acetolactate synthase activity
M483_RS06165	COG3085	chromosome segregation
M483_RS06175	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS06180	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS06185	COG1129	ABC transporter
M483_RS06190	COG1879	ABC-type sugar transport system periplasmic component
M483_RS06245	COG0151	Belongs to the GarS family
M483_RS06265	COG1515	deoxyribonuclease V activity
M483_RS06305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M483_RS06360	COG0250	Participates in transcription elongation, termination and antitermination
M483_RS06420	COG2986	histidine ammonia-lyase
M483_RS06450	COG4607	ABC-type enterochelin transport system periplasmic component
M483_RS06460	COG4605	iron ion homeostasis
M483_RS06465	COG4604	ABC transporter, ATP-binding protein
M483_RS06505	COG0582	viral genome integration into host DNA
M483_RS06510	COG1609	Transcriptional regulator
M483_RS06510	COG2207	Transcriptional regulator
M483_RS06515	COG4214	carbohydrate transport
M483_RS06525	COG4213	ABC transporter substrate-binding protein
M483_RS06535	COG1070	Carbohydrate kinase
M483_RS06545	COG3121	Chaperone
M483_RS06560	COG3274	enterobacterial common antigen metabolic process
M483_RS06575	COG2801	Transposase and inactivated derivatives
M483_RS06585	COG0527	aspartate kinase activity
M483_RS06585	COG0460	homoserine dehydrogenase
M483_RS06590	COG0626	cystathionine gamma-synthase activity
M483_RS06605	COG4682	membrane
M483_RS06615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M483_RS06625	COG1609	Transcriptional regulator
M483_RS06630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M483_RS06645	COG1575	Belongs to the MenA family. Type 1 subfamily
M483_RS06695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M483_RS06700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M483_RS06705	COG1494	fructose-1,6-bisphosphatase
M483_RS06715	COG3152	Membrane
M483_RS06730	COG0583	DNA-binding transcription factor activity
M483_RS06735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M483_RS06740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M483_RS06755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M483_RS06775	COG3678	ATP-independent chaperone mediated protein folding
M483_RS06780	COG0745	RESPONSE REGULATOR receiver
M483_RS06785	COG2205	protein histidine kinase activity
M483_RS06790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M483_RS06790	COG2169	Transcriptional regulator
M483_RS06795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M483_RS06800	COG1045	serine acetyltransferase
M483_RS06820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M483_RS06825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M483_RS06835	COG4942	peptidase
M483_RS06850	COG0156	8-amino-7-oxononanoate synthase activity
M483_RS06860	COG0859	PFAM glycosyl transferase family 9
M483_RS06865	COG0859	PFAM glycosyl transferase family 9
M483_RS06870	COG1519	Transferase
M483_RS06905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M483_RS06930	COG1561	YicC-like family, N-terminal region
M483_RS06935	COG2860	membrane
M483_RS06955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M483_RS06960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M483_RS06965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M483_RS06970	COG0786	glutamate:sodium symporter activity
M483_RS06975	COG2233	PERMEase
M483_RS06980	COG2982	Protein involved in outer membrane biogenesis
M483_RS06985	COG0456	acetyltransferase
M483_RS07010	COG1011	Hydrolase
M483_RS07025	COG0174	glutamine synthetase
M483_RS07030	COG3852	Histidine kinase
M483_RS07040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M483_RS07055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M483_RS07055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M483_RS07060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M483_RS07065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M483_RS07070	COG3084	Protein conserved in bacteria
M483_RS07080	COG1763	Mo-molybdopterin cofactor biosynthetic process
M483_RS07085	COG3328	transposase activity
M483_RS07115	COG2186	Transcriptional regulator
M483_RS07120	COG0477	Major facilitator Superfamily
M483_RS07160	COG1522	sequence-specific DNA binding
M483_RS07165	COG0716	FMN binding
M483_RS07180	COG3312	ion transport
M483_RS07235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M483_RS07240	COG0573	inorganic phosphate transmembrane transporter activity
M483_RS07245	COG0581	inorganic phosphate transmembrane transporter activity
M483_RS07255	COG0704	Plays a role in the regulation of phosphate uptake
M483_RS07265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M483_RS07270	COG0765	amino acid transport
M483_RS07275	COG0765	amino acid transport
M483_RS07280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M483_RS07285	COG2252	PERMEase
M483_RS07310	COG0706	membrane insertase activity
M483_RS07320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M483_RS07330	COG0592	DNA-directed DNA polymerase activity
M483_RS07345	COG0187	DNA topoisomerase II activity
M483_RS07350	COG0561	phosphatase activity
M483_RS07355	COG2801	Transposase and inactivated derivatives
M483_RS07365	COG2423	ornithine cyclodeaminase activity
M483_RS07370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M483_RS07375	COG0823	Involved in the tonB-independent uptake of proteins
M483_RS07380	COG0823	Involved in the tonB-independent uptake of proteins
M483_RS07385	COG5645	(Lipo)protein
M483_RS07405	COG3977	Valine--pyruvate aminotransferase
M483_RS07415	COG0366	Alpha amylase catalytic
M483_RS07430	COG2885	chlorophyll binding
M483_RS07440	COG2818	Glycosylase
M483_RS07460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS07460	COG2213	PTS system mannitol-specific
M483_RS07470	COG3722	fumarate hydratase activity
M483_RS07495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M483_RS07505	COG3383	formate dehydrogenase (NAD+) activity
M483_RS07505	COG0243	molybdopterin cofactor binding
M483_RS07510	COG0243	molybdopterin cofactor binding
M483_RS07510	COG3383	formate dehydrogenase (NAD+) activity
M483_RS07515	COG0437	4 iron, 4 sulfur cluster binding
M483_RS07520	COG2864	formate dehydrogenase
M483_RS07535	COG3276	selenocysteine insertion sequence binding
M483_RS07545	COG3328	transposase activity
M483_RS07575	COG2801	Transposase and inactivated derivatives
M483_RS07585	COG1349	DNA-binding transcription factor activity
M483_RS07605	COG0058	SHG alpha-glucan phosphorylase activity
M483_RS07610	COG1640	4-alpha-glucanotransferase
M483_RS07645	COG1918	ferrous iron import across plasma membrane
M483_RS07655	COG2183	response to ionizing radiation
M483_RS07660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M483_RS07685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M483_RS07690	COG1011	Hydrolase
M483_RS07705	COG0494	nUDIX hydrolase
M483_RS07710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M483_RS07740	COG4796	Type ii and iii secretion system protein
M483_RS07765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M483_RS07770	COG0546	phosphoglycolate phosphatase activity
M483_RS07775	COG0180	Tryptophanyl-tRNA synthetase
M483_RS07795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M483_RS07800	COG0402	S-adenosylhomocysteine deaminase activity
M483_RS07825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M483_RS07830	COG0433	COG0433 Predicted ATPase
M483_RS07845	COG1289	transmembrane transporter activity
M483_RS07855	COG1765	OsmC-like protein
M483_RS07865	COG3954	Phosphoribulokinase
M483_RS07875	COG0429	hydrolase of the alpha beta-hydrolase fold
M483_RS07885	COG4521	taurine ABC transporter
M483_RS07895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M483_RS07900	COG2175	clavaminate synthase activity
M483_RS07910	COG1216	Glycosyl transferase, family 2
M483_RS07915	COG0488	(ABC) transporter
M483_RS07930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M483_RS07935	COG1047	Peptidyl-prolyl cis-trans
M483_RS07945	COG0545	Peptidyl-prolyl cis-trans isomerase
M483_RS07950	COG2964	Protein conserved in bacteria
M483_RS07975	COG0049	tRNA binding
M483_RS08010	COG0051	transcription antitermination factor activity, RNA binding
M483_RS08025	COG0089	rRNA binding
M483_RS08035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M483_RS08045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
M483_RS08050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M483_RS08060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M483_RS08065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M483_RS08105	COG1841	ribosomal large subunit assembly
M483_RS08115	COG0201	protein transport
M483_RS08120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M483_RS08135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M483_RS08150	COG0789	Transcriptional regulator
M483_RS08155	COG3036	rescue of stalled ribosome
M483_RS08185	COG0758	DNA mediated transformation
M483_RS08195	COG0551	DNA topoisomerase type I activity
M483_RS08210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M483_RS08240	COG2801	Transposase and inactivated derivatives
M483_RS08265	COG3162	membrane
M483_RS08275	COG1301	dicarboxylic acid transport
M483_RS08385	COG2391	methyltransferase activity
M483_RS08390	COG0425	Belongs to the sulfur carrier protein TusA family
M483_RS08395	COG0583	DNA-binding transcription factor activity
M483_RS08400	COG0814	amino acid
M483_RS08405	COG0626	cystathionine gamma-synthase activity
M483_RS08415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M483_RS08420	COG4558	Periplasmic binding protein
M483_RS08425	COG3720	iron ion transport
M483_RS08430	COG4771	TonB-dependent receptor
M483_RS08440	COG0702	epimerase
M483_RS08445	COG3721	Heme iron utilization protein
M483_RS08470	COG1358	cellular component organization or biogenesis
M483_RS08530	COG3121	Chaperone
M483_RS08575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M483_RS08585	COG0735	belongs to the Fur family
M483_RS08590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M483_RS08615	COG1448	Aminotransferase
M483_RS08620	COG2315	Protein conserved in bacteria
M483_RS08625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M483_RS08630	COG0629	single-stranded DNA binding
M483_RS08640	COG1454	alcohol dehydrogenase
M483_RS08710	COG1309	transcriptional regulator
M483_RS08715	COG0493	'glutamate synthase
M483_RS08715	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M483_RS08720	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
M483_RS08725	COG3383	formate dehydrogenase (NAD+) activity
M483_RS08740	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M483_RS08785	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
M483_RS08795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M483_RS08800	COG1053	succinate dehydrogenase
M483_RS08815	COG3264	Mechanosensitive ion channel
M483_RS08815	COG1511	domain protein
M483_RS08835	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M483_RS08845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M483_RS08850	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M483_RS08850	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M483_RS08855	COG0802	atpase or kinase
M483_RS08860	COG0860	N-Acetylmuramoyl-L-alanine amidase
M483_RS08880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M483_RS08885	COG0330	HflC and HflK could
M483_RS08890	COG0330	HflC and HflK could
M483_RS08895	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
M483_RS08915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M483_RS08920	COG1960	acyl-CoA dehydrogenase activity
M483_RS08925	COG3650	response to hydrogen peroxide
M483_RS08940	COG2194	sulfuric ester hydrolase activity
M483_RS08945	COG2197	response regulator
M483_RS08950	COG3851	Histidine kinase
M483_RS08955	COG2271	Major facilitator Superfamily
M483_RS08970	COG2831	hemolysin activation secretion protein
M483_RS08980	COG0747	negative chemotaxis
M483_RS08985	COG0601	transmembrane transport
M483_RS08995	COG0444	Belongs to the ABC transporter superfamily
M483_RS09000	COG4608	Belongs to the ABC transporter superfamily
M483_RS09005	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M483_RS09010	COG2199	diguanylate cyclase activity
M483_RS09010	COG2200	EAL domain
M483_RS09015	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M483_RS09035	COG0612	Peptidase, M16
M483_RS09040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M483_RS09045	COG1942	4-Oxalocrotonate Tautomerase
M483_RS09050	COG2200	EAL domain
M483_RS09055	COG2982	Protein involved in outer membrane biogenesis
M483_RS09060	COG2134	cdp-diacylglycerol pyrophosphatase
M483_RS09065	COG1295	ribonuclease BN
M483_RS09090	COG1929	Belongs to the glycerate kinase type-1 family
M483_RS09095	COG2610	gluconate transmembrane transporter activity
M483_RS09100	COG3835	regulator
M483_RS09105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M483_RS09110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M483_RS09115	COG0339	signal peptide processing
M483_RS09135	COG0589	response to stress
M483_RS09155	COG0306	phosphate transporter
M483_RS09160	COG2081	HI0933 family
M483_RS09175	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS09190	COG0191	fructose-bisphosphate aldolase activity
M483_RS09210	COG1741	Belongs to the pirin family
M483_RS09220	COG2610	gluconate transmembrane transporter activity
M483_RS09225	COG3265	gluconokinase activity
M483_RS09245	COG2095	MarC family integral membrane protein
M483_RS09250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M483_RS09280	COG2373	Large extracellular alpha-helical protein
M483_RS09280	COG4932	domain protein
M483_RS09280	COG2373	Large extracellular alpha-helical protein
M483_RS09280	COG4932	domain protein
M483_RS09280	COG1388	LysM domain
M483_RS09280	COG1388	LysM domain
M483_RS09285	COG3275	phosphorelay sensor kinase activity
M483_RS09310	COG0058	SHG alpha-glucan phosphorylase activity
M483_RS09315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M483_RS09335	COG2801	Transposase and inactivated derivatives
M483_RS09355	COG0513	Belongs to the DEAD box helicase family
M483_RS09375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M483_RS09385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M483_RS09395	COG0826	peptidase U32
M483_RS09400	COG0826	peptidase U32
M483_RS09410	COG3154	lipid carrier protein
M483_RS09415	COG3153	acetyltransferase
M483_RS09435	COG1653	transport
M483_RS09440	COG1175	transmembrane transport
M483_RS09445	COG0395	ABC-type sugar transport system, permease component
M483_RS09450	COG3842	ATPase activity
M483_RS09465	COG0702	epimerase
M483_RS09470	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M483_RS09475	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
M483_RS09480	COG3454	Phosphonate metabolism
M483_RS09485	COG4778	phosphonate C-P lyase system protein PhnL
M483_RS09490	COG4107	phosphonate C-P lyase system protein PhnK
M483_RS09495	COG3627	carbon phosphorus lyase activity
M483_RS09500	COG3626	phosphonate metabolism
M483_RS09505	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
M483_RS09510	COG3624	Phosphonate C-P lyase system protein PhnG
M483_RS09515	COG2188	Transcriptional regulator
M483_RS09530	COG4608	Belongs to the ABC transporter superfamily
M483_RS09535	COG0444	Belongs to the ABC transporter superfamily
M483_RS09540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M483_RS09545	COG0601	transmembrane transport
M483_RS09555	COG2731	YhcH YjgK YiaL family protein
M483_RS09565	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
M483_RS09575	COG0525	valine-tRNA ligase activity
M483_RS09580	COG2927	DNA polymerase III (CHI subunit)
M483_RS09590	COG0795	lipopolysaccharide-transporting ATPase activity
M483_RS09595	COG0795	lipopolysaccharide-transporting ATPase activity
M483_RS09605	COG0582	viral genome integration into host DNA
M483_RS09630	COG1401	restriction endodeoxyribonuclease activity
M483_RS09645	COG2963	transposase activity
M483_RS09700	COG4269	membrane
M483_RS09710	COG2207	Transcriptional regulator
M483_RS09715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M483_RS09720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M483_RS09725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M483_RS09730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M483_RS09730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS09730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS09775	COG2390	Transcriptional regulator
M483_RS09785	COG0859	PFAM glycosyl transferase family 9
M483_RS09805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M483_RS09810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M483_RS09855	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
M483_RS09860	COG0456	acetyltransferase
M483_RS09870	COG2823	Periplasmic or secreted lipoprotein
M483_RS09880	COG4667	esterase of the alpha-beta hydrolase superfamily
M483_RS09885	COG0084	hydrolase, TatD family'
M483_RS09890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M483_RS09915	COG3726	membrane protein affecting hemolysin expression
M483_RS09920	COG0560	Phosphoserine phosphatase
M483_RS09940	COG0488	(ABC) transporter
M483_RS09945	COG2885	chlorophyll binding
M483_RS09950	COG2199	diguanylate cyclase activity
M483_RS09965	COG0741	lytic transglycosylase activity
M483_RS09970	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
M483_RS09985	COG3708	Transcriptional regulator
M483_RS09985	COG2207	Transcriptional regulator
M483_RS09990	COG3045	CreA protein
M483_RS09995	COG0745	RESPONSE REGULATOR receiver
M483_RS10025	COG0521	Mo-molybdopterin cofactor biosynthetic process
M483_RS10040	COG1584	GPR1 FUN34 yaaH family protein
M483_RS10060	COG0583	DNA-binding transcription factor activity
M483_RS10075	COG0196	riboflavin kinase activity
M483_RS10090	COG1047	Peptidyl-prolyl cis-trans
M483_RS10115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M483_RS10120	COG1280	lysine exporter protein (LysE YggA)
M483_RS10125	COG2966	Psort location CytoplasmicMembrane, score
M483_RS10135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M483_RS10185	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
M483_RS10190	COG0564	pseudouridine synthase activity
M483_RS10275	COG3047	cAMP biosynthetic process
M483_RS10275	COG2885	chlorophyll binding
M483_RS10295	COG0417	DNA replication proofreading
M483_RS10300	COG0586	Pfam SNARE associated Golgi protein
M483_RS10305	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
M483_RS10310	COG1178	ABC-type Fe3 transport system permease component
M483_RS10315	COG4143	(ABC) transporter
M483_RS10335	COG2814	Major facilitator Superfamily
M483_RS10350	COG0473	3-isopropylmalate dehydrogenase activity
M483_RS10370	COG1022	Amp-dependent synthetase and ligase
M483_RS10375	COG3328	transposase activity
M483_RS10385	COG0028	Belongs to the TPP enzyme family
M483_RS10405	COG1609	Transcriptional regulator
M483_RS10430	COG3116	cell division
M483_RS10435	COG0768	penicillin binding
M483_RS10440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M483_RS10445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M483_RS10460	COG0772	Belongs to the SEDS family
M483_RS10480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M483_RS10485	COG0849	cell division
M483_RS10490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M483_RS10515	COG0494	nUDIX hydrolase
M483_RS10560	COG1459	type II secretion system
M483_RS10565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M483_RS10570	COG4969	Belongs to the N-Me-Phe pilin family
M483_RS10580	COG3023	N-Acetylmuramoyl-L-alanine amidase
M483_RS10585	COG3725	Membrane protein required for beta-lactamase induction
M483_RS10590	COG1113	amino acid transport
M483_RS10595	COG2186	Transcriptional regulator
M483_RS10600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
M483_RS10605	COG0508	dehydrogenase complex catalyzes the overall conversion of
M483_RS10610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M483_RS10625	COG1049	propionate catabolic process, 2-methylcitrate cycle
M483_RS10635	COG0697	spore germination
M483_RS10655	COG2132	Multicopper oxidase
M483_RS10660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M483_RS10665	COG0288	reversible hydration of carbon dioxide
M483_RS10670	COG1131	(ABC) transporter
M483_RS10675	COG0842	Transport permease protein
M483_RS10700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M483_RS10705	COG0617	tRNA 3'-terminal CCA addition
M483_RS10710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M483_RS10725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M483_RS10730	COG1643	Atp-dependent helicase
M483_RS10735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M483_RS10740	COG1120	ATPase activity
M483_RS10745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M483_RS10750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M483_RS10770	COG2860	membrane
M483_RS10790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M483_RS10795	COG2205	protein histidine kinase activity
M483_RS10795	COG3437	response regulator, receiver
M483_RS10795	COG3850	Histidine kinase
M483_RS10795	COG4999	Histidine kinase
M483_RS10800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M483_RS10810	COG3956	TIGRFAM MazG family protein
M483_RS10830	COG0602	queuosine metabolic process
M483_RS10835	COG0720	synthase
M483_RS10885	COG0529	Catalyzes the synthesis of activated sulfate
M483_RS10925	COG1388	LysM domain
M483_RS10925	COG4942	peptidase
M483_RS10930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M483_RS10945	COG0698	ribose 5-phosphate isomerase
M483_RS10950	COG1063	alcohol dehydrogenase
M483_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS10960	COG2376	Dihydroxyacetone kinase
M483_RS10975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M483_RS10995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M483_RS11000	COG1858	cytochrome C peroxidase
M483_RS11010	COG4771	TonB-dependent receptor
M483_RS11035	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M483_RS11035	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M483_RS11040	COG1070	Carbohydrate kinase
M483_RS11045	COG3623	hexulose-6-phosphate isomerase
M483_RS11050	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS11055	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS11060	COG1129	ABC transporter
M483_RS11070	COG1349	DNA-binding transcription factor activity
M483_RS11075	COG0235	Class ii aldolase
M483_RS11080	COG0243	molybdopterin cofactor binding
M483_RS11085	COG0437	4 iron, 4 sulfur cluster binding
M483_RS11090	COG3302	dmso reductase anchor subunit
M483_RS11095	COG3381	protein complex oligomerization
M483_RS11100	COG3038	cytochrome b561
M483_RS11105	COG3783	Cytochrome b(562)
M483_RS11115	COG1879	ABC-type sugar transport system periplasmic component
M483_RS11125	COG1129	ABC transporter
M483_RS11130	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS11135	COG3959	Transketolase, thiamine diphosphate binding domain
M483_RS11140	COG3958	Transketolase
M483_RS11145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M483_RS11185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
M483_RS11205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M483_RS11210	COG1238	metal cluster binding
M483_RS11215	COG2918	glutathione biosynthetic process
M483_RS11235	COG4536	flavin adenine dinucleotide binding
M483_RS11240	COG4137	Cytochrome C assembly protein
M483_RS11245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M483_RS11270	COG3137	Salt-induced outer membrane protein
M483_RS11280	COG3279	Response regulator of the LytR AlgR family
M483_RS11285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M483_RS11300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M483_RS11305	COG0287	Prephenate dehydrogenase
M483_RS11305	COG1605	Chorismate mutase
M483_RS11310	COG0077	Prephenate dehydratase
M483_RS11310	COG1605	Chorismate mutase
M483_RS11315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M483_RS11320	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M483_RS11325	COG0564	pseudouridine synthase activity
M483_RS11335	COG0542	response to heat
M483_RS11380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M483_RS11385	COG2224	Isocitrate lyase
M483_RS11395	COG1414	Transcriptional regulator
M483_RS11415	COG0527	aspartate kinase activity
M483_RS11430	COG3833	ABC-type maltose transport systems, permease component
M483_RS11435	COG1175	transmembrane transport
M483_RS11495	COG2801	Transposase and inactivated derivatives
M483_RS11610	COG3501	Rhs element vgr protein
M483_RS11620	COG3209	COG3209 Rhs family protein
M483_RS11635	COG0673	inositol 2-dehydrogenase activity
M483_RS11640	COG1917	Cupin 2, conserved barrel domain protein
M483_RS11640	COG2207	Transcriptional regulator
M483_RS11645	COG1869	D-ribose catabolic process
M483_RS11650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M483_RS11655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M483_RS11660	COG0431	NADPH-dependent FMN reductase
M483_RS11665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M483_RS11675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M483_RS11685	COG3077	Addiction module antitoxin, RelB DinJ family
M483_RS11690	COG2252	PERMEase
M483_RS11695	COG0025	NhaP-type Na H and K H
M483_RS11705	COG1560	Kdo2-lipid A biosynthetic process
M483_RS11715	COG1129	ABC transporter
M483_RS11720	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS11730	COG1069	ribulokinase activity
M483_RS11740	COG0625	glutathione transferase activity
M483_RS11765	COG1278	Cold shock
M483_RS11770	COG1278	Cold shock
M483_RS11780	COG3133	Outer membrane lipoprotein
M483_RS11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M483_RS11795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M483_RS11820	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M483_RS11825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M483_RS11835	COG4145	pantothenate transmembrane transporter activity
M483_RS11840	COG3924	membrane
M483_RS11845	COG0439	Biotin carboxylase
M483_RS11850	COG0511	ligase activity, forming carbon-carbon bonds
M483_RS11865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M483_RS11870	COG0604	alcohol dehydrogenase
M483_RS11875	COG2199	diguanylate cyclase activity
M483_RS11875	COG2200	EAL domain
M483_RS11880	COG1077	Cell shape determining protein MreB Mrl
M483_RS11885	COG1792	Involved in formation and maintenance of cell shape
M483_RS11890	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M483_RS11895	COG0424	maF-like protein
M483_RS11900	COG1530	ribonuclease E activity
M483_RS11905	COG3164	Protein of unknown function
M483_RS11910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M483_RS11915	COG0312	modulator of DNA gyrase
M483_RS11965	COG0583	DNA-binding transcription factor activity
M483_RS11985	COG1012	belongs to the aldehyde dehydrogenase family
M483_RS12000	COG2732	(Barnase) inhibitor
M483_RS12010	COG0312	modulator of DNA gyrase
M483_RS12020	COG3783	Cytochrome b(562)
M483_RS12025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M483_RS12030	COG0366	Alpha amylase catalytic
M483_RS12035	COG1263	PTS System
M483_RS12035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M483_RS12065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS12085	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M483_RS12090	COG1137	ATPase activity
M483_RS12095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M483_RS12100	COG3117	lipopolysaccharide transmembrane transporter activity
M483_RS12105	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M483_RS12110	COG0517	IMP dehydrogenase activity
M483_RS12110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M483_RS12115	COG0530	calcium, potassium:sodium antiporter activity
M483_RS12120	COG1127	ABC transporter
M483_RS12125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M483_RS12130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M483_RS12135	COG2854	intermembrane phospholipid transfer
M483_RS12140	COG3113	response to antibiotic
M483_RS12145	COG5007	Belongs to the BolA IbaG family
M483_RS12155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M483_RS12165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M483_RS12170	COG3105	Protein conserved in bacteria
M483_RS12175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M483_RS12195	COG0625	glutathione transferase activity
M483_RS12200	COG2969	positive regulation of protein catabolic process
M483_RS12210	COG0493	'glutamate synthase
M483_RS12215	COG0069	glutamate synthase activity
M483_RS12215	COG0070	glutamate synthase
M483_RS12215	COG0067	glutamate synthase
M483_RS12220	COG1242	4 iron, 4 sulfur cluster binding
M483_RS12230	COG5002	protein histidine kinase activity
M483_RS12230	COG2198	Histidine kinase
M483_RS12230	COG0784	Response regulator, receiver
M483_RS12250	COG2823	Periplasmic or secreted lipoprotein
M483_RS12270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M483_RS12275	COG1741	Belongs to the pirin family
M483_RS12280	COG0583	DNA-binding transcription factor activity
M483_RS12285	COG0435	Glutathione S-transferase
M483_RS12290	COG2259	Doxx family
M483_RS12300	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
M483_RS12305	COG4575	ribosome binding
M483_RS12325	COG0586	Pfam SNARE associated Golgi protein
M483_RS12360	COG2721	sulfolactate sulfo-lyase activity
M483_RS12380	COG0673	inositol 2-dehydrogenase activity
M483_RS12385	COG1451	nucleotide metabolic process
M483_RS12400	COG0446	pyridine nucleotide-disulphide oxidoreductase
M483_RS12400	COG1902	pentaerythritol trinitrate reductase activity
M483_RS12405	COG3247	response to pH
M483_RS12425	COG4245	von Willebrand factor, type A
M483_RS12440	COG4245	von Willebrand factor, type A
M483_RS12445	COG2831	hemolysin activation secretion protein
M483_RS12450	COG3210	domain, Protein
M483_RS12475	COG3210	domain, Protein
M483_RS12480	COG3210	domain, Protein
M483_RS12500	COG3842	ATPase activity
M483_RS12505	COG3459	Glycosyltransferase 36 associated
M483_RS12510	COG1609	Transcriptional regulator
M483_RS12515	COG2182	Extracellular solute-binding protein
M483_RS12525	COG0395	ABC-type sugar transport system, permease component
M483_RS12545	COG1289	transmembrane transporter activity
M483_RS12570	COG0436	Aminotransferase
M483_RS12590	COG0251	oxidation-reduction process
M483_RS12690	COG0358	DNA primase activity
M483_RS12695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M483_RS12710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M483_RS12725	COG4991	sh3 domain protein
M483_RS12730	COG3025	triphosphatase activity
M483_RS12745	COG0531	amino acid
M483_RS12765	COG3384	dioxygenase
M483_RS12770	COG0754	glutathionylspermidine amidase activity
M483_RS12785	COG1538	Outer membrane efflux protein
M483_RS12790	COG0494	nUDIX hydrolase
M483_RS12795	COG3151	Protein conserved in bacteria
M483_RS12800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M483_RS12805	COG3150	esterase
M483_RS12815	COG0583	DNA-binding transcription factor activity
M483_RS12820	COG2249	NAD(P)H dehydrogenase (quinone) activity
M483_RS12825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M483_RS12835	COG2132	Multicopper oxidase
M483_RS12845	COG0656	L-ascorbic acid biosynthetic process
M483_RS12855	COG1979	alcohol dehydrogenase
M483_RS12860	COG2207	Transcriptional regulator
M483_RS12865	COG0586	Pfam SNARE associated Golgi protein
M483_RS12870	COG0626	cystathionine gamma-synthase activity
M483_RS12875	COG0811	peptide transport
M483_RS12880	COG0848	biopolymer transport protein
M483_RS12930	COG4964	Belongs to the GSP D family
M483_RS12935	COG4964	Belongs to the GSP D family
M483_RS12970	COG4592	Periplasmic binding protein
M483_RS12990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M483_RS12995	COG1684	flagellar biosynthetic protein fliR
M483_RS13000	COG1987	bacterial-type flagellum assembly
M483_RS13025	COG1677	Flagellar hook-basal body complex protein FliE
M483_RS13065	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
M483_RS13070	COG1815	bacterial-type flagellum-dependent cell motility
M483_RS13075	COG1558	bacterial-type flagellum-dependent cell motility
M483_RS13080	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M483_RS13085	COG1749	Flagellar hook protein flgE
M483_RS13090	COG4787	bacterial-type flagellum-dependent cell motility
M483_RS13095	COG4786	Flagellar basal body rod
M483_RS13105	COG1706	bacterial-type flagellum-dependent cell motility
M483_RS13115	COG1256	bacterial-type flagellum assembly
M483_RS13135	COG3710	Transcriptional regulator
M483_RS13160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M483_RS13185	COG1191	sigma factor activity
M483_RS13190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M483_RS13220	COG3133	Outer membrane lipoprotein
M483_RS13235	COG2801	Transposase and inactivated derivatives
M483_RS13240	COG2211	Major facilitator Superfamily
M483_RS13290	COG2771	luxR family
M483_RS13295	COG3916	Acyl-homoserine-lactone synthase
M483_RS13400	COG1982	Orn Lys Arg decarboxylase major
M483_RS13405	COG1879	ABC-type sugar transport system periplasmic component
M483_RS13410	COG1129	ABC transporter
M483_RS13415	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS13420	COG4774	siderophore transport
M483_RS13440	COG1194	a g-specific adenine glycosylase
M483_RS13450	COG3171	Protein conserved in bacteria
M483_RS13470	COG3064	Membrane
M483_RS13470	COG1073	alpha beta
M483_RS13470	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
M483_RS13475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M483_RS13480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M483_RS13490	COG0762	integral membrane protein
M483_RS13495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M483_RS13500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M483_RS13505	COG2805	Type II/IV secretion system protein
M483_RS13515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M483_RS13530	COG0189	ligase activity
M483_RS13535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M483_RS13540	COG2356	endonuclease I
M483_RS13555	COG1166	arginine decarboxylase activity
M483_RS13565	COG0501	Belongs to the peptidase M48B family
M483_RS13570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M483_RS13590	COG0191	fructose-bisphosphate aldolase activity
M483_RS13625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M483_RS13635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M483_RS13650	COG0006	proline dipeptidase activity
M483_RS13655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M483_RS13660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M483_RS13690	COG5295	Hep Hag repeat protein
M483_RS13700	COG1272	protein, Hemolysin III
M483_RS13725	COG0745	RESPONSE REGULATOR receiver
M483_RS13730	COG2205	protein histidine kinase activity
M483_RS13735	COG4452	Inner membrane protein CreD
M483_RS13740	COG0716	FMN binding
M483_RS13745	COG4974	Belongs to the 'phage' integrase family
M483_RS13750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M483_RS13755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M483_RS13775	COG0582	viral genome integration into host DNA
M483_RS13805	COG2944	sequence-specific DNA binding
M483_RS13900	COG1695	Transcriptional regulator
M483_RS13905	COG0791	NLP P60 protein
M483_RS13915	COG1879	ABC-type sugar transport system periplasmic component
M483_RS13920	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS13925	COG1129	ABC transporter
M483_RS13935	COG2182	Extracellular solute-binding protein
M483_RS13940	COG1175	transmembrane transport
M483_RS13945	COG3833	ABC-type maltose transport systems, permease component
M483_RS13950	COG3867	Arabinogalactan endo-beta-1,4-galactanase
M483_RS13960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M483_RS13960	COG1263	PTS System
M483_RS13980	COG2271	Major facilitator Superfamily
M483_RS14010	COG3119	arylsulfatase activity
M483_RS14015	COG0641	radical SAM
M483_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS14035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS14040	COG3716	PTS system mannose fructose sorbose family IID component
M483_RS14045	COG3715	PTS system
M483_RS14050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M483_RS14055	COG2222	sugar isomerase
M483_RS14065	COG1349	DNA-binding transcription factor activity
M483_RS14070	COG3119	arylsulfatase activity
M483_RS14110	COG0288	reversible hydration of carbon dioxide
M483_RS14130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M483_RS14195	COG3328	transposase activity
M483_RS14210	COG0840	transmembrane signaling receptor activity
M483_RS14225	COG0583	DNA-binding transcription factor activity
M483_RS14230	COG2814	Major facilitator Superfamily
M483_RS14235	COG0583	DNA-binding transcription factor activity
M483_RS14245	COG1609	Transcriptional regulator
M483_RS14275	COG0667	Aldo Keto reductase
M483_RS14340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M483_RS14350	COG1074	ATP-dependent DNA helicase activity
M483_RS14355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M483_RS14375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M483_RS14375	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M483_RS14380	COG0860	N-Acetylmuramoyl-L-alanine amidase
M483_RS14395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
M483_RS14400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M483_RS14405	COG2166	iron-sulfur cluster assembly
M483_RS14410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M483_RS14415	COG0583	DNA-binding transcription factor activity
M483_RS14420	COG2363	Small membrane protein
M483_RS14435	COG1611	Belongs to the LOG family
M483_RS14455	COG3098	single-species biofilm formation
M483_RS14460	COG0564	pseudouridine synthase activity
M483_RS14520	COG0575	Belongs to the CDS family
M483_RS14525	COG0750	zinc metalloprotease
M483_RS14540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M483_RS14565	COG0587	DNA-directed DNA polymerase activity
M483_RS14575	COG0346	lactoylglutathione lyase activity
M483_RS14580	COG0037	tRNA processing
M483_RS14590	COG4568	rho-dependent transcription termination
M483_RS14600	COG4681	YaeQ
M483_RS14610	COG3015	lipoprotein NlpE involved in copper resistance
M483_RS14620	COG1720	tRNA m6t6A37 methyltransferase activity
M483_RS14630	COG1464	Belongs to the NlpA lipoprotein family
M483_RS14635	COG2011	ABC-type metal ion transport system permease component
M483_RS14645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M483_RS14675	COG0656	L-ascorbic acid biosynthetic process
M483_RS14690	COG0741	lytic transglycosylase activity
M483_RS14690	COG1388	LysM domain
M483_RS14700	COG2226	methyltransferase
M483_RS14720	COG1953	Uracil, thiamine, allantoin
M483_RS14735	COG2113	Glycine betaine
M483_RS14740	COG4176	ABC-type proline glycine betaine transport system permease component
M483_RS14745	COG4175	Glycine betaine
M483_RS14750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M483_RS14790	COG1278	Cold shock
M483_RS14795	COG0747	negative chemotaxis
M483_RS14805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M483_RS14810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
M483_RS14815	COG1124	(ABC) transporter
M483_RS14820	COG0831	urea catabolic process
M483_RS14845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
M483_RS14855	COG4413	Urea transporter
M483_RS14860	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
M483_RS14875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M483_RS14885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M483_RS14895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M483_RS14900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M483_RS14905	COG1447	Phosphotransferase system cellobiose-specific component IIA
M483_RS14910	COG1917	Cupin 2, conserved barrel domain protein
M483_RS14910	COG2169	Transcriptional regulator
M483_RS14930	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
M483_RS14935	COG0033	Phosphoglucomutase
M483_RS14955	COG0745	RESPONSE REGULATOR receiver
M483_RS14995	COG3272	Protein of unknown function (DUF1722)
M483_RS15005	COG5212	phosphodiesterase
M483_RS15010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M483_RS15020	COG1984	allophanate hydrolase subunit 2
M483_RS15070	COG0513	Belongs to the DEAD box helicase family
M483_RS15080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M483_RS15095	COG3026	antisigma factor binding
M483_RS15100	COG3086	response to oxidative stress
M483_RS15135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M483_RS15155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M483_RS15170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M483_RS15185	COG1067	ATP-dependent peptidase activity
M483_RS15215	COG3070	regulator of competence-specific genes
M483_RS15220	COG1289	transmembrane transporter activity
M483_RS15225	COG3304	Inner membrane component domain
M483_RS15230	COG0210	DNA helicase
M483_RS15245	COG1832	CoA-binding protein
M483_RS15265	COG2920	part of a sulfur-relay system
M483_RS15300	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS15310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M483_RS15315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M483_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS15325	COG3425	synthase
M483_RS15335	COG1024	Enoyl-CoA hydratase
M483_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS15350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M483_RS15355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M483_RS15490	COG0488	(ABC) transporter
M483_RS15505	COG0303	'Molybdopterin
M483_RS15515	COG1136	(ABC) transporter
M483_RS15545	COG0583	DNA-binding transcription factor activity
M483_RS15550	COG0477	Major facilitator Superfamily
M483_RS15560	COG2311	Membrane
M483_RS15575	COG4211	Belongs to the binding-protein-dependent transport system permease family
M483_RS15595	COG2949	membrane
M483_RS15610	COG1346	cytolysis
M483_RS15620	COG2814	Major facilitator Superfamily
M483_RS15655	COG0489	protein tyrosine kinase activity
M483_RS15670	COG2982	Protein involved in outer membrane biogenesis
M483_RS15675	COG1253	flavin adenine dinucleotide binding
M483_RS15680	COG4114	ferric iron reductase
M483_RS15685	COG0076	glutamate decarboxylase activity
M483_RS15690	COG3486	L-lysine 6-monooxygenase (NADPH) activity
M483_RS15705	COG1120	ATPase activity
M483_RS15710	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M483_RS15715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M483_RS15720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M483_RS15735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M483_RS15740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M483_RS15750	COG0140	phosphoribosyl-ATP diphosphatase activity
M483_RS15750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M483_RS15770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M483_RS15770	COG0131	Imidazoleglycerol-phosphate dehydratase
M483_RS15780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M483_RS15790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M483_RS15800	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS15805	COG1129	ABC transporter
M483_RS15810	COG1129	ABC transporter
M483_RS15815	COG0371	Dehydrogenase
M483_RS15825	COG0531	amino acid
M483_RS15830	COG2925	Exonuclease
M483_RS15845	COG3328	transposase activity
M483_RS15850	COG1470	cell adhesion involved in biofilm formation
M483_RS15850	COG1388	LysM domain
M483_RS15855	COG2271	Major facilitator Superfamily
M483_RS15860	COG3011	Protein conserved in bacteria
M483_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS15875	COG4948	Mandelate Racemase Muconate Lactonizing
M483_RS15890	COG0534	Mate efflux family protein
M483_RS15910	COG3122	Protein conserved in bacteria
M483_RS15935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M483_RS15955	COG2223	nitrite transmembrane transporter activity
M483_RS15995	COG1132	(ABC) transporter
M483_RS16005	COG2207	Transcriptional regulator
M483_RS16040	COG1113	amino acid transport
M483_RS16065	COG1496	oxidoreductase activity
M483_RS16070	COG2226	methyltransferase
M483_RS16080	COG5002	protein histidine kinase activity
M483_RS16080	COG3447	MASE1 domain protein
M483_RS16080	COG5001	Diguanylate cyclase
M483_RS16100	COG3716	PTS system mannose fructose sorbose family IID component
M483_RS16105	COG3715	PTS system
M483_RS16110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M483_RS16110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS16120	COG1846	Transcriptional regulator
M483_RS16135	COG1012	belongs to the aldehyde dehydrogenase family
M483_RS16140	COG3384	dioxygenase
M483_RS16150	COG3971	2-oxopent-4-enoate hydratase activity
M483_RS16165	COG2368	4-hydroxyphenylacetate
M483_RS16170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M483_RS16175	COG1760	l-serine dehydratase
M483_RS16200	COG0513	Belongs to the DEAD box helicase family
M483_RS16205	COG3141	response to X-ray
M483_RS16220	COG1770	oligopeptidase
M483_RS16235	COG1528	Iron-storage protein
M483_RS16240	COG2372	response to copper ion
M483_RS16270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M483_RS16275	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M483_RS16295	COG3418	PFAM FlgN family protein
M483_RS16300	COG2747	anti-sigma28 factor FlgM
M483_RS16310	COG1815	bacterial-type flagellum-dependent cell motility
M483_RS16315	COG1558	bacterial-type flagellum-dependent cell motility
M483_RS16355	COG1256	bacterial-type flagellum assembly
M483_RS16365	COG2390	Transcriptional regulator
M483_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS16370	COG3347	Dehydrogenase
M483_RS16375	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS16385	COG1129	ABC transporter
M483_RS16390	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS16395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M483_RS16415	COG1987	bacterial-type flagellum assembly
M483_RS16440	COG1580	Controls the rotational direction of flagella during chemotaxis
M483_RS16455	COG1157	protein secretion by the type III secretion system
M483_RS16475	COG1677	Flagellar hook-basal body complex protein FliE
M483_RS16490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M483_RS16495	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
M483_RS16530	COG1191	sigma factor activity
M483_RS16550	COG0765	amino acid transport
M483_RS16555	COG1126	abc transporter atp-binding protein
M483_RS16570	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M483_RS16570	COG0506	proline dehydrogenase activity
M483_RS16570	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M483_RS16585	COG0672	)-iron permease
M483_RS16590	COG2822	iron ion transport
M483_RS16610	COG1113	amino acid transport
M483_RS16630	COG3136	membrane protein required for alginate biosynthesis
M483_RS16640	COG2197	response regulator
M483_RS16780	COG2188	Transcriptional regulator
M483_RS16790	COG0673	inositol 2-dehydrogenase activity
M483_RS16800	COG1175	transmembrane transport
M483_RS16805	COG0395	ABC-type sugar transport system, permease component
M483_RS16810	COG3842	ATPase activity
M483_RS16880	COG4771	TonB-dependent receptor
M483_RS16885	COG1021	2,3-dihydroxybenzoate-AMP ligase
M483_RS16905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M483_RS16905	COG2226	methyltransferase
M483_RS16905	COG3433	isochorismatase activity
M483_RS16920	COG1132	(ABC) transporter
M483_RS16925	COG2814	Major facilitator Superfamily
M483_RS16930	COG1169	isochorismate synthase
M483_RS16935	COG0582	viral genome integration into host DNA
M483_RS16950	COG3328	transposase activity
M483_RS16955	COG3121	Chaperone
M483_RS16965	COG3188	usher protein
M483_RS16980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M483_RS16980	COG2205	protein histidine kinase activity
M483_RS16990	COG0427	acetyl-CoA hydrolase
M483_RS16995	COG2030	dehydratase
M483_RS17020	COG2814	Major facilitator Superfamily
M483_RS17035	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
M483_RS17040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M483_RS17050	COG1349	DNA-binding transcription factor activity
M483_RS17055	COG2066	Belongs to the glutaminase family
M483_RS17080	COG0577	efflux transmembrane transporter activity
M483_RS17080	COG1136	(ABC) transporter
M483_RS17090	COG0577	efflux transmembrane transporter activity
M483_RS17090	COG1136	(ABC) transporter
M483_RS17110	COG0006	proline dipeptidase activity
M483_RS17115	COG0457	Tetratricopeptide repeat
M483_RS17120	COG1649	PFAM Uncharacterised BCR, COG1649
M483_RS17120	COG0726	polysaccharide deacetylase
M483_RS17125	COG1215	transferase activity, transferring glycosyl groups
M483_RS17130	COG3658	cytochrome
M483_RS17145	COG1702	phosphate starvation-inducible protein PhoH
M483_RS17150	COG0387	Pfam Sodium calcium exchanger
M483_RS17155	COG3850	Histidine kinase
M483_RS17160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M483_RS17200	COG3328	transposase activity
M483_RS17235	COG0402	S-adenosylhomocysteine deaminase activity
M483_RS17250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M483_RS17255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M483_RS17260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M483_RS17305	COG3328	transposase activity
M483_RS17330	COG0500	methyltransferase
M483_RS17370	COG5002	protein histidine kinase activity
M483_RS17390	COG0745	RESPONSE REGULATOR receiver
M483_RS17440	COG0012	GTP binding
M483_RS17460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M483_RS17490	COG2890	protein-(glutamine-N5) methyltransferase activity
M483_RS17510	COG0659	secondary active sulfate transmembrane transporter activity
M483_RS17535	COG3833	ABC-type maltose transport systems, permease component
M483_RS17540	COG1176	ABC-type spermidine putrescine transport system, permease component I
M483_RS17555	COG3842	ATPase activity
M483_RS17560	COG0584	glycerophosphoryl diester phosphodiesterase
M483_RS17565	COG1940	carbohydrate kinase activity
M483_RS17580	COG3381	protein complex oligomerization
M483_RS17595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M483_RS17600	COG0673	inositol 2-dehydrogenase activity
M483_RS17605	COG0728	peptidoglycan biosynthetic process
M483_RS17625	COG3102	Protein conserved in bacteria
M483_RS17645	COG3788	relative of glutathione S-transferase, MAPEG superfamily
M483_RS17650	COG1801	Protein of unknown function DUF72
M483_RS17660	COG0494	nUDIX hydrolase
M483_RS17685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M483_RS17695	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
M483_RS17700	COG0739	heme binding
M483_RS17705	COG1560	Kdo2-lipid A biosynthetic process
M483_RS17710	COG0469	pyruvate kinase activity
M483_RS17715	COG1737	Transcriptional regulator
M483_RS17720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M483_RS17725	COG0800	Aldolase
M483_RS17740	COG0251	oxidation-reduction process
M483_RS17745	COG1199	ATP-dependent helicase activity
M483_RS17760	COG0318	PFAM AMP-dependent synthetase and ligase
M483_RS17765	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
M483_RS17770	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
M483_RS17775	COG2894	cell division
M483_RS17790	COG2951	lytic endotransglycosylase activity
M483_RS17795	COG0179	Fumarylacetoacetate (FAA) hydrolase
M483_RS17805	COG0582	viral genome integration into host DNA
M483_RS18075	COG1104	cysteine desulfurase activity
M483_RS18105	COG2719	SpoVR family
M483_RS18115	COG2814	Major facilitator Superfamily
M483_RS18125	COG0583	DNA-binding transcription factor activity
M483_RS18140	COG2766	serine protein kinase
M483_RS18145	COG3713	MltA-interacting MipA family protein
M483_RS18165	COG3139	Protein of unknown function (DUF1315)
M483_RS18170	COG1335	isochorismatase
M483_RS18175	COG0252	asparaginase activity
M483_RS18180	COG0616	signal peptide processing
M483_RS18185	COG0778	Nitroreductase
M483_RS18190	COG0709	Synthesizes selenophosphate from selenide and ATP
M483_RS18195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M483_RS18205	COG0494	nUDIX hydrolase
M483_RS18210	COG0708	Exodeoxyribonuclease III
M483_RS18215	COG0583	DNA-binding transcription factor activity
M483_RS18225	COG0788	formyltetrahydrofolate deformylase activity
M483_RS18235	COG0745	RESPONSE REGULATOR receiver
M483_RS18245	COG3328	transposase activity
M483_RS18260	COG1454	alcohol dehydrogenase
M483_RS18260	COG1012	belongs to the aldehyde dehydrogenase family
M483_RS18265	COG2095	MarC family integral membrane protein
M483_RS18275	COG0601	transmembrane transport
M483_RS18280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M483_RS18285	COG0444	Belongs to the ABC transporter superfamily
M483_RS18290	COG4608	Belongs to the ABC transporter superfamily
M483_RS18330	COG2350	Protein conserved in bacteria
M483_RS18335	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
M483_RS18340	COG3328	transposase activity
M483_RS18375	COG3047	cAMP biosynthetic process
M483_RS18395	COG0135	phosphoribosylanthranilate isomerase activity
M483_RS18395	COG0134	indole-3-glycerol-phosphate synthase activity
M483_RS18405	COG0512	Glutamine amidotransferase of anthranilate synthase
M483_RS18430	COG0009	L-threonylcarbamoyladenylate synthase
M483_RS18435	COG1187	pseudouridine synthase activity
M483_RS18445	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS18450	COG0616	signal peptide processing
M483_RS18475	COG0583	DNA-binding transcription factor activity
M483_RS18485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M483_RS18495	COG0671	phosphoesterase, PA-phosphatase related
M483_RS18500	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
M483_RS18505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
M483_RS18520	COG0023	Translation Initiation Factor
M483_RS18540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M483_RS18545	COG2879	small protein
M483_RS18550	COG1966	Carbon starvation protein
M483_RS18560	COG2271	Major facilitator Superfamily
M483_RS18565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M483_RS18570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M483_RS18580	COG4659	FMN binding
M483_RS18585	COG4658	electron transport chain
M483_RS18590	COG3708	Transcriptional regulator
M483_RS18590	COG2207	Transcriptional regulator
M483_RS18620	COG1132	(ABC) transporter
M483_RS18630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M483_RS18635	COG2274	protein secretion by the type I secretion system
M483_RS18650	COG1879	ABC-type sugar transport system periplasmic component
M483_RS18655	COG1129	ABC transporter
M483_RS18670	COG0673	inositol 2-dehydrogenase activity
M483_RS18675	COG0385	Bile acid
M483_RS18685	COG5339	Protein conserved in bacteria
M483_RS18695	COG0114	fumarate hydratase activity
M483_RS18710	COG0583	DNA-binding transcription factor activity
M483_RS18715	COG1940	carbohydrate kinase activity
M483_RS18720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M483_RS18725	COG0038	chloride channel
M483_RS18740	COG1609	Transcriptional regulator
M483_RS18760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M483_RS18770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M483_RS18795	COG0028	Belongs to the TPP enzyme family
M483_RS18800	COG0440	acetolactate synthase activity
M483_RS18805	COG1011	Hydrolase
M483_RS18825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M483_RS18830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M483_RS18835	COG0589	response to stress
M483_RS18840	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
M483_RS18845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
M483_RS18860	COG0531	amino acid
M483_RS18870	COG0745	RESPONSE REGULATOR receiver
M483_RS18875	COG2205	protein histidine kinase activity
M483_RS18880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M483_RS18915	COG3038	cytochrome b561
M483_RS18930	COG3591	Belongs to the peptidase S1B family
M483_RS18945	COG1643	Atp-dependent helicase
M483_RS18955	COG2390	Transcriptional regulator
M483_RS18960	COG0246	Mannitol dehydrogenase
M483_RS18965	COG3784	Protein of unknown function (DUF1318)
M483_RS18975	COG2911	Protein conserved in bacteria
M483_RS18980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M483_RS18985	COG3187	Heat shock protein
M483_RS18990	COG3042	response to heat
M483_RS18995	COG1285	pathogenesis
M483_RS19005	COG1013	pyruvate-flavodoxin oxidoreductase activity
M483_RS19005	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M483_RS19005	COG0674	pyruvate-flavodoxin oxidoreductase activity
M483_RS19005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M483_RS19015	COG0657	acetylesterase activity
M483_RS19030	COG4166	transmembrane transport
M483_RS19035	COG2866	Carboxypeptidase
M483_RS19040	COG4948	Mandelate Racemase Muconate Lactonizing
M483_RS19045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M483_RS19070	COG5642	Protein of unknown function (DUF2384)
M483_RS19075	COG5654	RES domain protein
M483_RS19085	COG3106	COG3106 Predicted ATPase
M483_RS19095	COG1983	PspC domain protein
M483_RS19105	COG1842	Phage shock protein A
M483_RS19110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M483_RS19135	COG4166	transmembrane transport
M483_RS19140	COG4168	peptide transport system, permease
M483_RS19145	COG4171	peptide transport system, permease
M483_RS19155	COG4172	Belongs to the ABC transporter superfamily
M483_RS19160	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M483_RS19160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M483_RS19165	COG3104	oligopeptide transport
M483_RS19180	COG0625	glutathione transferase activity
M483_RS19200	COG3895	Periplasmic Protein
M483_RS19210	COG3133	Outer membrane lipoprotein
M483_RS19220	COG4989	oxidoreductase activity
M483_RS19225	COG3313	Fe-S protein
M483_RS19230	COG2194	sulfuric ester hydrolase activity
M483_RS19235	COG1309	transcriptional regulator
M483_RS19240	COG1902	pentaerythritol trinitrate reductase activity
M483_RS19250	COG0346	lactoylglutathione lyase activity
M483_RS19260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M483_RS19270	COG0791	NLP P60 protein
M483_RS19285	COG0583	DNA-binding transcription factor activity
M483_RS19290	COG2814	Major facilitator Superfamily
M483_RS19295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M483_RS19300	COG0307	riboflavin synthase, alpha
M483_RS19355	COG1376	ErfK ybiS ycfS ynhG family protein
M483_RS19355	COG1388	LysM domain
M483_RS19370	COG0719	Fe-S assembly protein
M483_RS19375	COG0396	ATPase activity
M483_RS19380	COG0719	Fe-S assembly protein
M483_RS19385	COG0316	Belongs to the HesB IscA family
M483_RS19395	COG2050	protein possibly involved in aromatic compounds catabolism
M483_RS19400	COG0277	FAD linked oxidase domain protein
M483_RS19400	COG0247	lactate metabolic process
M483_RS19405	COG0628	permease
M483_RS19410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M483_RS19410	COG0574	Belongs to the PEP-utilizing enzyme family
M483_RS19435	COG0791	NLP P60 protein
M483_RS19480	COG0386	Belongs to the glutathione peroxidase family
M483_RS19495	COG0776	regulation of translation
M483_RS19500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M483_RS19500	COG0072	phenylalanine-tRNA ligase activity
M483_RS19530	COG4249	Peptidase C14 caspase catalytic subunit p20
M483_RS19555	COG0803	Belongs to the bacterial solute-binding protein 9 family
M483_RS19560	COG1121	(ABC) transporter
M483_RS19565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M483_RS19570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M483_RS19580	COG3001	Fructosamine kinase
M483_RS19590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M483_RS19595	COG3328	transposase activity
M483_RS19600	COG1917	Cupin 2, conserved barrel domain protein
M483_RS19610	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS19620	COG1175	transmembrane transport
M483_RS19625	COG0395	ABC-type sugar transport system, permease component
M483_RS19630	COG3842	ATPase activity
M483_RS19635	COG1653	transport
M483_RS19640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M483_RS19645	COG1988	membrane-bound metal-dependent
M483_RS19650	COG1823	symporter activity
M483_RS19655	COG3023	N-Acetylmuramoyl-L-alanine amidase
M483_RS19665	COG0823	Involved in the tonB-independent uptake of proteins
M483_RS19670	COG2814	Major facilitator Superfamily
M483_RS19675	COG3121	Chaperone
M483_RS19690	COG3121	Chaperone
M483_RS19695	COG3539	Fimbrial protein
M483_RS19705	COG0793	Belongs to the peptidase S41A family
M483_RS19715	COG1956	GAF domain-containing protein
M483_RS19720	COG2995	paraquat-inducible protein a
M483_RS19725	COG3008	intermembrane lipid transfer
M483_RS19745	COG3121	Chaperone
M483_RS19800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M483_RS19810	COG5295	Hep Hag repeat protein
M483_RS19820	COG3023	N-Acetylmuramoyl-L-alanine amidase
M483_RS19830	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
M483_RS19835	COG0745	RESPONSE REGULATOR receiver
M483_RS19845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M483_RS19850	COG0840	transmembrane signaling receptor activity
M483_RS19855	COG0840	transmembrane signaling receptor activity
M483_RS19875	COG2964	Protein conserved in bacteria
M483_RS19885	COG0251	oxidation-reduction process
M483_RS19890	COG2271	Major facilitator Superfamily
M483_RS19895	COG0835	chemotaxis
M483_RS19900	COG0643	Histidine kinase
M483_RS19900	COG2198	Histidine kinase
M483_RS19905	COG1360	Flagellar Motor Protein
M483_RS19930	COG1285	pathogenesis
M483_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS19960	COG3321	synthase
M483_RS19960	COG0604	alcohol dehydrogenase
M483_RS19970	COG1522	sequence-specific DNA binding
M483_RS19995	COG1733	regulation of RNA biosynthetic process
M483_RS20000	COG0702	epimerase
M483_RS20005	COG0840	transmembrane signaling receptor activity
M483_RS20020	COG0538	isocitrate dehydrogenase activity
M483_RS20025	COG1187	pseudouridine synthase activity
M483_RS20045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M483_RS20055	COG0745	RESPONSE REGULATOR receiver
M483_RS20065	COG2850	peptidyl-arginine hydroxylation
M483_RS20080	COG1940	carbohydrate kinase activity
M483_RS20085	COG4591	ABC-type transport system involved in lipoprotein release permease component
M483_RS20095	COG4591	ABC-type transport system involved in lipoprotein release permease component
M483_RS20100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M483_RS20105	COG3134	Outer membrane lipoprotein
M483_RS20110	COG3328	transposase activity
M483_RS20125	COG1252	NADH dehydrogenase
M483_RS20135	COG1472	Belongs to the glycosyl hydrolase 3 family
M483_RS20150	COG5633	Lipoprotein
M483_RS20155	COG0537	adenosine 5'-monophosphoramidase activity
M483_RS20160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M483_RS20170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M483_RS20170	COG1263	PTS System
M483_RS20175	COG0084	hydrolase, TatD family'
M483_RS20180	COG0470	DNA polymerase III
M483_RS20190	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M483_RS20195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M483_RS20205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M483_RS20235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M483_RS20240	COG1399	metal-binding, possibly nucleic acid-binding protein
M483_RS20245	COG0424	maF-like protein
M483_RS20250	COG0564	pseudouridine synthase activity
M483_RS20255	COG1530	ribonuclease E activity
M483_RS20260	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M483_RS20285	COG3328	transposase activity
M483_RS20300	COG0628	permease
M483_RS20330	COG3916	Acyl-homoserine-lactone synthase
M483_RS20335	COG2771	luxR family
M483_RS20340	COG0583	DNA-binding transcription factor activity
M483_RS20350	COG0477	Major facilitator Superfamily
M483_RS20360	COG0667	Aldo Keto reductase
M483_RS20385	COG1203	CRISPR-associated helicase, Cas3
M483_RS20390	COG1518	maintenance of DNA repeat elements
M483_RS20395	COG0668	transmembrane transport
M483_RS20415	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
M483_RS20420	COG0395	ABC-type sugar transport system, permease component
M483_RS20435	COG1609	Transcriptional regulator
M483_RS20445	COG3842	ATPase activity
M483_RS20455	COG3328	transposase activity
M483_RS20465	COG3210	domain, Protein
M483_RS20485	COG3210	domain, Protein
M483_RS20505	COG3210	domain, Protein
M483_RS20510	COG2831	hemolysin activation secretion protein
M483_RS20515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M483_RS20520	COG4638	Rieske (2fe-2S)
M483_RS20525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M483_RS20535	COG0473	3-isopropylmalate dehydrogenase activity
M483_RS20540	COG0583	DNA-binding transcription factor activity
M483_RS20545	COG1609	Transcriptional regulator
M483_RS20550	COG1172	Belongs to the binding-protein-dependent transport system permease family
M483_RS20560	COG1879	ABC-type sugar transport system periplasmic component
M483_RS20565	COG1063	alcohol dehydrogenase
M483_RS20585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M483_RS20615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M483_RS20620	COG0765	amino acid transport
M483_RS20625	COG1126	abc transporter atp-binding protein
M483_RS20645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M483_RS20660	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M483_RS20675	COG1169	isochorismate synthase
M483_RS20685	COG4575	ribosome binding
M483_RS20700	COG0129	dihydroxy-acid dehydratase activity
M483_RS20715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M483_RS20725	COG1609	Transcriptional regulator
M483_RS20730	COG1649	PFAM Uncharacterised BCR, COG1649
M483_RS20735	COG1028	Short-chain dehydrogenase reductase Sdr
M483_RS20740	COG3265	gluconokinase activity
M483_RS20745	COG2731	YhcH YjgK YiaL family protein
M483_RS20760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M483_RS20765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M483_RS20775	COG0839	Belongs to the complex I subunit 6 family
M483_RS20790	COG1034	ATP synthesis coupled electron transport
M483_RS20810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M483_RS20820	COG0583	DNA-binding transcription factor activity
M483_RS20830	COG0436	Aminotransferase
M483_RS20845	COG0471	metal ion transport
M483_RS20845	COG0490	domain, Protein
M483_RS20850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M483_RS20875	COG0857	belongs to the CobB CobQ family
M483_RS20875	COG0280	phosphate acetyltransferase
M483_RS20880	COG1609	Transcriptional regulator
M483_RS20895	COG3037	sugar-specific permease SgaT UlaA
M483_RS20900	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
M483_RS20915	COG1090	epimerase
M483_RS20920	COG4598	ABC transporter
M483_RS20925	COG4160	amino acid transport
M483_RS20930	COG4215	(ABC) transporter
M483_RS20935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M483_RS20945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M483_RS20950	COG1286	toxin biosynthetic process
M483_RS20955	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
M483_RS20960	COG0285	dihydrofolate synthase activity
M483_RS20970	COG0586	Pfam SNARE associated Golgi protein
M483_RS20980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M483_RS21000	COG0697	spore germination
M483_RS21015	COG1794	racemase activity, acting on amino acids and derivatives
M483_RS21020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M483_RS21035	COG3101	peptidyl-lysine hydroxylation
M483_RS21040	COG0730	response to heat
M483_RS21055	COG2890	protein-(glutamine-N5) methyltransferase activity
M483_RS21065	COG2062	phosphohistidine phosphatase, SixA
M483_RS21080	COG3691	Protein conserved in bacteria
M483_RS21095	COG3088	subunit of a heme lyase
M483_RS21095	COG4235	cytochrome complex assembly
M483_RS21100	COG4235	cytochrome complex assembly
M483_RS21100	COG3088	subunit of a heme lyase
M483_RS21105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M483_RS21110	COG1138	Cytochrome C-type biogenesis protein
M483_RS21120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M483_RS21125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M483_RS21130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M483_RS21150	COG1704	LemA family
M483_RS21160	COG2824	Alkylphosphonate utilization operon protein PhnA
M483_RS21250	COG3188	usher protein
M483_RS21260	COG3188	usher protein
M483_RS21265	COG3121	Chaperone
M483_RS21325	COG2951	lytic endotransglycosylase activity
M483_RS21360	COG0243	molybdopterin cofactor binding
M483_RS21365	COG0437	4 iron, 4 sulfur cluster binding
M483_RS21370	COG3302	dmso reductase anchor subunit
M483_RS21375	COG3381	protein complex oligomerization
M483_RS21405	COG3038	cytochrome b561
M483_RS21410	COG0436	Aminotransferase
M483_RS21435	COG0667	Aldo Keto reductase
M483_RS21500	COG3530	Putative quorum-sensing-regulated virulence factor
M483_RS21515	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
M483_RS21525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M483_RS21555	COG2205	protein histidine kinase activity
M483_RS21560	COG0745	RESPONSE REGULATOR receiver
M483_RS21565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M483_RS21580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M483_RS21600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M483_RS21610	COG5002	protein histidine kinase activity
M483_RS21610	COG3850	Histidine kinase
M483_RS21615	COG0745	RESPONSE REGULATOR receiver
M483_RS21630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M483_RS21635	COG4208	sulfate ABC transporter
M483_RS21640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M483_RS21645	COG4150	thiosulfate binding
M483_RS21655	COG1737	Transcriptional regulator
M483_RS21665	COG2731	YhcH YjgK YiaL family protein
M483_RS21675	COG4886	Leucine-rich repeat (LRR) protein
M483_RS21685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M483_RS21690	COG2837	iron assimilation
M483_RS21700	COG3111	PFAM Bacterial OB fold (BOF) protein
M483_RS21745	COG3005	denitrification pathway
M483_RS21750	COG3043	anaerobic respiration
M483_RS21760	COG3062	negative regulation of establishment of protein localization
M483_RS21765	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
M483_RS21765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M483_RS21770	COG2197	response regulator
M483_RS21780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M483_RS21790	COG1988	membrane-bound metal-dependent
M483_RS21795	COG0641	radical SAM
M483_RS21800	COG3119	arylsulfatase activity
M483_RS21805	COG3842	ATPase activity
M483_RS21810	COG1175	transmembrane transport
M483_RS21825	COG1393	Belongs to the ArsC family
M483_RS21835	COG1876	peptidase activity
M483_RS21855	COG2321	neutral zinc metallopeptidase
M483_RS21875	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
M483_RS21885	COG2716	regulation of RNA biosynthetic process
M483_RS21890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M483_RS21910	COG0628	permease
M483_RS21915	COG4783	chaperone-mediated protein folding
M483_RS21920	COG1393	Belongs to the ArsC family
M483_RS21945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M483_RS21950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M483_RS21970	COG0581	inorganic phosphate transmembrane transporter activity
M483_RS21980	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M483_RS21995	COG2239	Acts as a magnesium transporter
M483_RS22000	COG0443	Heat shock 70 kDa protein
M483_RS22005	COG1177	transmembrane transport
M483_RS22010	COG1176	ABC-type spermidine putrescine transport system, permease component I
M483_RS22020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family