locus-tag	class	description
A1122_RS00050	COG2771	luxR family
A1122_RS00055	COG3916	Acyl-homoserine-lactone synthase
A1122_RS00190	COG1982	Orn Lys Arg decarboxylase major
A1122_RS00195	COG1879	ABC-type sugar transport system periplasmic component
A1122_RS00200	COG1129	ABC transporter
A1122_RS00205	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS00210	COG4774	siderophore transport
A1122_RS00230	COG1194	a g-specific adenine glycosylase
A1122_RS00240	COG3171	Protein conserved in bacteria
A1122_RS00260	COG3064	Membrane
A1122_RS00260	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
A1122_RS00260	COG1073	alpha beta
A1122_RS00265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1122_RS00270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A1122_RS00280	COG0762	integral membrane protein
A1122_RS00285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A1122_RS00290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A1122_RS00295	COG2805	Type II/IV secretion system protein
A1122_RS00305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1122_RS00320	COG0189	ligase activity
A1122_RS00325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A1122_RS00330	COG2356	endonuclease I
A1122_RS00335	COG3091	SprT-like family
A1122_RS00345	COG1166	arginine decarboxylase activity
A1122_RS00355	COG0501	Belongs to the peptidase M48B family
A1122_RS00360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A1122_RS00390	COG0191	fructose-bisphosphate aldolase activity
A1122_RS00425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A1122_RS00430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A1122_RS00445	COG0006	proline dipeptidase activity
A1122_RS00450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1122_RS00455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1122_RS00485	COG5295	Hep Hag repeat protein
A1122_RS00495	COG1272	protein, Hemolysin III
A1122_RS00520	COG0745	RESPONSE REGULATOR receiver
A1122_RS00525	COG2205	protein histidine kinase activity
A1122_RS00530	COG4452	Inner membrane protein CreD
A1122_RS00535	COG0716	FMN binding
A1122_RS00540	COG4974	Belongs to the 'phage' integrase family
A1122_RS00545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1122_RS00550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A1122_RS00570	COG0582	viral genome integration into host DNA
A1122_RS00600	COG2944	sequence-specific DNA binding
A1122_RS00695	COG1695	Transcriptional regulator
A1122_RS00700	COG0791	NLP P60 protein
A1122_RS00710	COG1879	ABC-type sugar transport system periplasmic component
A1122_RS00715	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS00720	COG1129	ABC transporter
A1122_RS00730	COG2182	Extracellular solute-binding protein
A1122_RS00735	COG1175	transmembrane transport
A1122_RS00740	COG3833	ABC-type maltose transport systems, permease component
A1122_RS00745	COG3867	Arabinogalactan endo-beta-1,4-galactanase
A1122_RS00750	COG1874	Beta-galactosidase
A1122_RS00755	COG1263	PTS System
A1122_RS00755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_RS00775	COG2271	Major facilitator Superfamily
A1122_RS00805	COG3119	arylsulfatase activity
A1122_RS00810	COG0641	radical SAM
A1122_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS00830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS00835	COG3716	PTS system mannose fructose sorbose family IID component
A1122_RS00840	COG3715	PTS system
A1122_RS00845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_RS00850	COG2222	sugar isomerase
A1122_RS00860	COG1349	DNA-binding transcription factor activity
A1122_RS00865	COG3119	arylsulfatase activity
A1122_RS00910	COG0288	reversible hydration of carbon dioxide
A1122_RS00930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A1122_RS01000	COG0840	transmembrane signaling receptor activity
A1122_RS01015	COG0583	DNA-binding transcription factor activity
A1122_RS01020	COG2814	Major facilitator Superfamily
A1122_RS01025	COG0583	DNA-binding transcription factor activity
A1122_RS01035	COG1609	Transcriptional regulator
A1122_RS01065	COG0667	Aldo Keto reductase
A1122_RS01125	COG3433	isochorismatase activity
A1122_RS01125	COG2226	methyltransferase
A1122_RS01125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1122_RS01135	COG3433	isochorismatase activity
A1122_RS01135	COG2226	methyltransferase
A1122_RS01135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A1122_RS01165	COG2375	cellular response to nickel ion
A1122_RS01165	COG1132	(ABC) transporter
A1122_RS01170	COG1132	(ABC) transporter
A1122_RS01185	COG2610	gluconate transmembrane transporter activity
A1122_RS01200	COG3501	Rhs element vgr protein
A1122_RS01210	COG3209	COG3209 Rhs family protein
A1122_RS01225	COG0471	metal ion transport
A1122_RS01240	COG2801	Transposase and inactivated derivatives
A1122_RS01285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A1122_RS01290	COG1191	sigma factor activity
A1122_RS01315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A1122_RS01335	COG3710	Transcriptional regulator
A1122_RS01355	COG1256	bacterial-type flagellum assembly
A1122_RS01365	COG1706	bacterial-type flagellum-dependent cell motility
A1122_RS01375	COG4786	Flagellar basal body rod
A1122_RS01400	COG1749	Flagellar hook protein flgE
A1122_RS01405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A1122_RS01410	COG1558	bacterial-type flagellum-dependent cell motility
A1122_RS01415	COG1815	bacterial-type flagellum-dependent cell motility
A1122_RS01420	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
A1122_RS01460	COG1677	Flagellar hook-basal body complex protein FliE
A1122_RS01485	COG1987	bacterial-type flagellum assembly
A1122_RS01490	COG1684	flagellar biosynthetic protein fliR
A1122_RS01495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1122_RS01515	COG4592	Periplasmic binding protein
A1122_RS01560	COG4964	Belongs to the GSP D family
A1122_RS01565	COG4964	Belongs to the GSP D family
A1122_RS01615	COG0848	biopolymer transport protein
A1122_RS01620	COG0811	peptide transport
A1122_RS01625	COG0626	cystathionine gamma-synthase activity
A1122_RS01630	COG0586	Pfam SNARE associated Golgi protein
A1122_RS01635	COG2207	Transcriptional regulator
A1122_RS01640	COG1979	alcohol dehydrogenase
A1122_RS01650	COG0656	L-ascorbic acid biosynthetic process
A1122_RS01660	COG2132	Multicopper oxidase
A1122_RS01670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A1122_RS01675	COG2249	NAD(P)H dehydrogenase (quinone) activity
A1122_RS01680	COG0583	DNA-binding transcription factor activity
A1122_RS01690	COG3150	esterase
A1122_RS01695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A1122_RS01700	COG3151	Protein conserved in bacteria
A1122_RS01705	COG0494	nUDIX hydrolase
A1122_RS01710	COG1538	Outer membrane efflux protein
A1122_RS01725	COG0754	glutathionylspermidine amidase activity
A1122_RS01730	COG3384	dioxygenase
A1122_RS01750	COG0531	amino acid
A1122_RS01765	COG3025	triphosphatase activity
A1122_RS01770	COG4991	sh3 domain protein
A1122_RS01785	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A1122_RS01800	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A1122_RS01805	COG0358	DNA primase activity
A1122_RS01900	COG0251	oxidation-reduction process
A1122_RS01920	COG0436	Aminotransferase
A1122_RS01945	COG1289	transmembrane transporter activity
A1122_RS01965	COG0395	ABC-type sugar transport system, permease component
A1122_RS01975	COG2182	Extracellular solute-binding protein
A1122_RS01980	COG1609	Transcriptional regulator
A1122_RS01985	COG3459	Glycosyltransferase 36 associated
A1122_RS01990	COG3842	ATPase activity
A1122_RS02010	COG3210	domain, Protein
A1122_RS02015	COG3210	domain, Protein
A1122_RS02040	COG3210	domain, Protein
A1122_RS02045	COG2831	hemolysin activation secretion protein
A1122_RS02050	COG4245	von Willebrand factor, type A
A1122_RS02065	COG4245	von Willebrand factor, type A
A1122_RS02085	COG3247	response to pH
A1122_RS02090	COG1902	pentaerythritol trinitrate reductase activity
A1122_RS02090	COG0446	pyridine nucleotide-disulphide oxidoreductase
A1122_RS02105	COG1451	nucleotide metabolic process
A1122_RS02110	COG0673	inositol 2-dehydrogenase activity
A1122_RS02130	COG2721	sulfolactate sulfo-lyase activity
A1122_RS02150	COG2271	Major facilitator Superfamily
A1122_RS02165	COG0586	Pfam SNARE associated Golgi protein
A1122_RS02185	COG4575	ribosome binding
A1122_RS02190	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
A1122_RS02200	COG2259	Doxx family
A1122_RS02205	COG0435	Glutathione S-transferase
A1122_RS02220	COG0494	nUDIX hydrolase
A1122_RS02245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A1122_RS02250	COG0849	cell division
A1122_RS02255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A1122_RS02275	COG0772	Belongs to the SEDS family
A1122_RS02290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A1122_RS02295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A1122_RS02300	COG0768	penicillin binding
A1122_RS02305	COG3116	cell division
A1122_RS02325	COG1609	Transcriptional regulator
A1122_RS02345	COG0028	Belongs to the TPP enzyme family
A1122_RS02355	COG1022	Amp-dependent synthetase and ligase
A1122_RS02390	COG0473	3-isopropylmalate dehydrogenase activity
A1122_RS02405	COG2814	Major facilitator Superfamily
A1122_RS02420	COG2814	Major facilitator Superfamily
A1122_RS02440	COG4143	(ABC) transporter
A1122_RS02445	COG1178	ABC-type Fe3 transport system permease component
A1122_RS02450	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A1122_RS02455	COG0586	Pfam SNARE associated Golgi protein
A1122_RS02460	COG0417	DNA replication proofreading
A1122_RS02480	COG3047	cAMP biosynthetic process
A1122_RS02480	COG2885	chlorophyll binding
A1122_RS02570	COG0564	pseudouridine synthase activity
A1122_RS02575	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
A1122_RS02630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A1122_RS02640	COG2966	Psort location CytoplasmicMembrane, score
A1122_RS02645	COG1280	lysine exporter protein (LysE YggA)
A1122_RS02650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A1122_RS02685	COG1047	Peptidyl-prolyl cis-trans
A1122_RS02700	COG0196	riboflavin kinase activity
A1122_RS02715	COG0583	DNA-binding transcription factor activity
A1122_RS02735	COG1584	GPR1 FUN34 yaaH family protein
A1122_RS02750	COG0521	Mo-molybdopterin cofactor biosynthetic process
A1122_RS02780	COG0745	RESPONSE REGULATOR receiver
A1122_RS02785	COG3045	CreA protein
A1122_RS02790	COG3708	Transcriptional regulator
A1122_RS02790	COG2207	Transcriptional regulator
A1122_RS02805	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
A1122_RS02810	COG0741	lytic transglycosylase activity
A1122_RS02825	COG2199	diguanylate cyclase activity
A1122_RS02830	COG2885	chlorophyll binding
A1122_RS02855	COG0560	Phosphoserine phosphatase
A1122_RS02860	COG3726	membrane protein affecting hemolysin expression
A1122_RS02900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1122_RS02905	COG0084	hydrolase, TatD family'
A1122_RS02910	COG4667	esterase of the alpha-beta hydrolase superfamily
A1122_RS02920	COG2823	Periplasmic or secreted lipoprotein
A1122_RS02930	COG0456	acetyltransferase
A1122_RS02935	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
A1122_RS02980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_RS02985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_RS03005	COG0859	PFAM glycosyl transferase family 9
A1122_RS03010	COG1070	Carbohydrate kinase
A1122_RS03060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A1122_RS03060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS03060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS03065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_RS03070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_RS03075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_RS03080	COG2207	Transcriptional regulator
A1122_RS03090	COG4269	membrane
A1122_RS03145	COG2963	transposase activity
A1122_RS03160	COG1401	restriction endodeoxyribonuclease activity
A1122_RS03180	COG3650	response to hydrogen peroxide
A1122_RS03185	COG1960	acyl-CoA dehydrogenase activity
A1122_RS03190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1122_RS03195	COG0557	exoribonuclease II activity
A1122_RS03210	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
A1122_RS03215	COG0330	HflC and HflK could
A1122_RS03220	COG0330	HflC and HflK could
A1122_RS03225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A1122_RS03245	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1122_RS03250	COG0802	atpase or kinase
A1122_RS03255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A1122_RS03255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A1122_RS03260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A1122_RS03275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A1122_RS03295	COG3264	Mechanosensitive ion channel
A1122_RS03295	COG1511	domain protein
A1122_RS03310	COG1053	succinate dehydrogenase
A1122_RS03315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A1122_RS03325	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
A1122_RS03380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1122_RS03395	COG3383	formate dehydrogenase (NAD+) activity
A1122_RS03400	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_RS03405	COG0493	'glutamate synthase
A1122_RS03405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_RS03410	COG1309	transcriptional regulator
A1122_RS03480	COG1454	alcohol dehydrogenase
A1122_RS03490	COG0629	single-stranded DNA binding
A1122_RS03495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A1122_RS03500	COG2315	Protein conserved in bacteria
A1122_RS03505	COG1448	Aminotransferase
A1122_RS03530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1122_RS03535	COG0735	belongs to the Fur family
A1122_RS03545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A1122_RS03590	COG3121	Chaperone
A1122_RS03650	COG1358	cellular component organization or biogenesis
A1122_RS03675	COG3721	Heme iron utilization protein
A1122_RS03680	COG0702	epimerase
A1122_RS03685	COG4771	TonB-dependent receptor
A1122_RS03690	COG3720	iron ion transport
A1122_RS03695	COG4558	Periplasmic binding protein
A1122_RS03700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_RS03710	COG0626	cystathionine gamma-synthase activity
A1122_RS03715	COG0814	amino acid
A1122_RS03720	COG0583	DNA-binding transcription factor activity
A1122_RS03725	COG0425	Belongs to the sulfur carrier protein TusA family
A1122_RS03730	COG2391	methyltransferase activity
A1122_RS03840	COG1301	dicarboxylic acid transport
A1122_RS03850	COG3162	membrane
A1122_RS03875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A1122_RS03890	COG0551	DNA topoisomerase type I activity
A1122_RS03900	COG0758	DNA mediated transformation
A1122_RS03930	COG3036	rescue of stalled ribosome
A1122_RS03935	COG0789	Transcriptional regulator
A1122_RS03950	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A1122_RS03965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A1122_RS03970	COG0201	protein transport
A1122_RS03980	COG1841	ribosomal large subunit assembly
A1122_RS04020	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A1122_RS04025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A1122_RS04035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A1122_RS04040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A1122_RS04050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A1122_RS04060	COG0089	rRNA binding
A1122_RS04075	COG0051	transcription antitermination factor activity, RNA binding
A1122_RS04105	COG0049	tRNA binding
A1122_RS04110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A1122_RS04130	COG2964	Protein conserved in bacteria
A1122_RS04135	COG0545	Peptidyl-prolyl cis-trans isomerase
A1122_RS04145	COG1047	Peptidyl-prolyl cis-trans
A1122_RS04150	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A1122_RS04170	COG1216	Glycosyl transferase, family 2
A1122_RS04180	COG2175	clavaminate synthase activity
A1122_RS04185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1122_RS04195	COG4521	taurine ABC transporter
A1122_RS04205	COG0429	hydrolase of the alpha beta-hydrolase fold
A1122_RS04215	COG3954	Phosphoribulokinase
A1122_RS04225	COG1765	OsmC-like protein
A1122_RS04235	COG1289	transmembrane transporter activity
A1122_RS04250	COG0433	COG0433 Predicted ATPase
A1122_RS04255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A1122_RS04260	COG1486	melibiose metabolic process
A1122_RS04290	COG0402	S-adenosylhomocysteine deaminase activity
A1122_RS04295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A1122_RS04315	COG0180	Tryptophanyl-tRNA synthetase
A1122_RS04320	COG0546	phosphoglycolate phosphatase activity
A1122_RS04325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A1122_RS04350	COG4796	Type ii and iii secretion system protein
A1122_RS04380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A1122_RS04385	COG0494	nUDIX hydrolase
A1122_RS04400	COG1011	Hydrolase
A1122_RS04405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A1122_RS04430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1122_RS04435	COG2183	response to ionizing radiation
A1122_RS04445	COG1918	ferrous iron import across plasma membrane
A1122_RS04480	COG1640	4-alpha-glucanotransferase
A1122_RS04485	COG0058	SHG alpha-glucan phosphorylase activity
A1122_RS04490	COG0058	SHG alpha-glucan phosphorylase activity
A1122_RS04500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1122_RS04510	COG1349	DNA-binding transcription factor activity
A1122_RS04520	COG2801	Transposase and inactivated derivatives
A1122_RS04530	COG0527	aspartate kinase activity
A1122_RS04530	COG0460	homoserine dehydrogenase
A1122_RS04550	COG4682	membrane
A1122_RS04560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A1122_RS04570	COG1609	Transcriptional regulator
A1122_RS04575	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A1122_RS04590	COG1575	Belongs to the MenA family. Type 1 subfamily
A1122_RS04655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A1122_RS04660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A1122_RS04665	COG1494	fructose-1,6-bisphosphatase
A1122_RS04675	COG3152	Membrane
A1122_RS04690	COG0583	DNA-binding transcription factor activity
A1122_RS04695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A1122_RS04700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A1122_RS04705	COG0471	metal ion transport
A1122_RS04715	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A1122_RS04735	COG3678	ATP-independent chaperone mediated protein folding
A1122_RS04740	COG0745	RESPONSE REGULATOR receiver
A1122_RS04745	COG2205	protein histidine kinase activity
A1122_RS04750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A1122_RS04750	COG2169	Transcriptional regulator
A1122_RS04755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A1122_RS04760	COG1045	serine acetyltransferase
A1122_RS04780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1122_RS04785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A1122_RS04795	COG4942	peptidase
A1122_RS04810	COG0156	8-amino-7-oxononanoate synthase activity
A1122_RS04820	COG0859	PFAM glycosyl transferase family 9
A1122_RS04825	COG0859	PFAM glycosyl transferase family 9
A1122_RS04830	COG1519	Transferase
A1122_RS04865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A1122_RS04890	COG1561	YicC-like family, N-terminal region
A1122_RS04895	COG2860	membrane
A1122_RS04915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1122_RS04920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1122_RS04925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A1122_RS04930	COG0786	glutamate:sodium symporter activity
A1122_RS04935	COG2233	PERMEase
A1122_RS04940	COG2982	Protein involved in outer membrane biogenesis
A1122_RS04945	COG0456	acetyltransferase
A1122_RS04970	COG1011	Hydrolase
A1122_RS04985	COG0174	glutamine synthetase
A1122_RS04990	COG3852	Histidine kinase
A1122_RS05000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A1122_RS05025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1122_RS05025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A1122_RS05030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A1122_RS05035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A1122_RS05040	COG3084	Protein conserved in bacteria
A1122_RS05050	COG1763	Mo-molybdopterin cofactor biosynthetic process
A1122_RS05055	COG3328	transposase activity
A1122_RS05085	COG2186	Transcriptional regulator
A1122_RS05090	COG0477	Major facilitator Superfamily
A1122_RS05100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_RS05130	COG1522	sequence-specific DNA binding
A1122_RS05135	COG0716	FMN binding
A1122_RS05150	COG3312	ion transport
A1122_RS05205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A1122_RS05210	COG0573	inorganic phosphate transmembrane transporter activity
A1122_RS05215	COG0581	inorganic phosphate transmembrane transporter activity
A1122_RS05225	COG0704	Plays a role in the regulation of phosphate uptake
A1122_RS05235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS05240	COG0765	amino acid transport
A1122_RS05245	COG0765	amino acid transport
A1122_RS05250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_RS05255	COG2252	PERMEase
A1122_RS05280	COG0706	membrane insertase activity
A1122_RS05290	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A1122_RS05300	COG0592	DNA-directed DNA polymerase activity
A1122_RS05315	COG0187	DNA topoisomerase II activity
A1122_RS05320	COG0561	phosphatase activity
A1122_RS05325	COG2801	Transposase and inactivated derivatives
A1122_RS05335	COG2423	ornithine cyclodeaminase activity
A1122_RS05340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A1122_RS05345	COG0823	Involved in the tonB-independent uptake of proteins
A1122_RS05350	COG0823	Involved in the tonB-independent uptake of proteins
A1122_RS05355	COG5645	(Lipo)protein
A1122_RS05375	COG3977	Valine--pyruvate aminotransferase
A1122_RS05385	COG0366	Alpha amylase catalytic
A1122_RS05400	COG2885	chlorophyll binding
A1122_RS05410	COG2818	Glycosylase
A1122_RS05430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS05430	COG2213	PTS system mannitol-specific
A1122_RS05440	COG3722	fumarate hydratase activity
A1122_RS05465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A1122_RS05475	COG3383	formate dehydrogenase (NAD+) activity
A1122_RS05475	COG0243	molybdopterin cofactor binding
A1122_RS05480	COG3383	formate dehydrogenase (NAD+) activity
A1122_RS05480	COG0243	molybdopterin cofactor binding
A1122_RS05485	COG0437	4 iron, 4 sulfur cluster binding
A1122_RS05490	COG2864	formate dehydrogenase
A1122_RS05505	COG3276	selenocysteine insertion sequence binding
A1122_RS05510	COG3276	selenocysteine insertion sequence binding
A1122_RS05545	COG2801	Transposase and inactivated derivatives
A1122_RS05560	COG3274	enterobacterial common antigen metabolic process
A1122_RS05580	COG3121	Chaperone
A1122_RS05590	COG1070	Carbohydrate kinase
A1122_RS05600	COG4213	ABC transporter substrate-binding protein
A1122_RS05610	COG4214	carbohydrate transport
A1122_RS05615	COG1609	Transcriptional regulator
A1122_RS05615	COG2207	Transcriptional regulator
A1122_RS05620	COG0582	viral genome integration into host DNA
A1122_RS05660	COG4604	ABC transporter, ATP-binding protein
A1122_RS05665	COG4605	iron ion homeostasis
A1122_RS05675	COG4607	ABC-type enterochelin transport system periplasmic component
A1122_RS05705	COG2986	histidine ammonia-lyase
A1122_RS05720	COG2194	sulfuric ester hydrolase activity
A1122_RS05725	COG2197	response regulator
A1122_RS05730	COG3851	Histidine kinase
A1122_RS05735	COG2271	Major facilitator Superfamily
A1122_RS05750	COG2831	hemolysin activation secretion protein
A1122_RS05760	COG0747	negative chemotaxis
A1122_RS05765	COG0601	transmembrane transport
A1122_RS05770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_RS05775	COG0444	Belongs to the ABC transporter superfamily
A1122_RS05780	COG4608	Belongs to the ABC transporter superfamily
A1122_RS05785	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A1122_RS05790	COG2200	EAL domain
A1122_RS05790	COG2199	diguanylate cyclase activity
A1122_RS05795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A1122_RS05815	COG0612	Peptidase, M16
A1122_RS05820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_RS05825	COG1942	4-Oxalocrotonate Tautomerase
A1122_RS05830	COG2200	EAL domain
A1122_RS05835	COG2982	Protein involved in outer membrane biogenesis
A1122_RS05840	COG2134	cdp-diacylglycerol pyrophosphatase
A1122_RS05845	COG1295	ribonuclease BN
A1122_RS05870	COG1929	Belongs to the glycerate kinase type-1 family
A1122_RS05875	COG2610	gluconate transmembrane transporter activity
A1122_RS05880	COG3835	regulator
A1122_RS05885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1122_RS05890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A1122_RS05895	COG0339	signal peptide processing
A1122_RS05915	COG0589	response to stress
A1122_RS05930	COG0306	phosphate transporter
A1122_RS05935	COG2081	HI0933 family
A1122_RS05950	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS05965	COG0191	fructose-bisphosphate aldolase activity
A1122_RS05985	COG1741	Belongs to the pirin family
A1122_RS05990	COG1609	Transcriptional regulator
A1122_RS05995	COG2610	gluconate transmembrane transporter activity
A1122_RS06000	COG3265	gluconokinase activity
A1122_RS06020	COG2095	MarC family integral membrane protein
A1122_RS06025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A1122_RS06055	COG3275	phosphorelay sensor kinase activity
A1122_RS06080	COG0058	SHG alpha-glucan phosphorylase activity
A1122_RS06085	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1122_RS06105	COG2801	Transposase and inactivated derivatives
A1122_RS06140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A1122_RS06160	COG1629	transport
A1122_RS06185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1122_RS06190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A1122_RS06190	COG0678	peroxiredoxin activity
A1122_RS06270	COG1879	ABC-type sugar transport system periplasmic component
A1122_RS06275	COG1129	ABC transporter
A1122_RS06280	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS06285	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS06295	COG3085	chromosome segregation
A1122_RS06310	COG3978	acetolactate synthase activity
A1122_RS06315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1122_RS06360	COG0583	DNA-binding transcription factor activity
A1122_RS06400	COG3121	Chaperone
A1122_RS06415	COG3121	Chaperone
A1122_RS06430	COG3328	transposase activity
A1122_RS06440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1122_RS06470	COG3118	belongs to the thioredoxin family
A1122_RS06475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A1122_RS06480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A1122_RS06485	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A1122_RS06490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A1122_RS06495	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A1122_RS06500	COG1088	dTDP-glucose 4,6-dehydratase activity
A1122_RS06505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A1122_RS06510	COG0456	acetyltransferase
A1122_RS06515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A1122_RS06520	COG2244	polysaccharide biosynthetic process
A1122_RS06540	COG1113	amino acid transport
A1122_RS06580	COG3071	HemY protein
A1122_RS06585	COG2959	enzyme of heme biosynthesis
A1122_RS06590	COG1587	Uroporphyrinogen-III synthase
A1122_RS06600	COG3072	Adenylate cyclase
A1122_RS06620	COG3159	Protein conserved in bacteria
A1122_RS06625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A1122_RS06630	COG1011	Hydrolase
A1122_RS06635	COG0210	DNA helicase
A1122_RS06645	COG5441	Belongs to the UPF0261 family
A1122_RS06650	COG5564	TIM-barrel signal transduction protein
A1122_RS06665	COG2050	protein possibly involved in aromatic compounds catabolism
A1122_RS06670	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
A1122_RS06675	COG0514	ATP-dependent DNA helicase (RecQ)
A1122_RS06680	COG1280	lysine exporter protein (LysE YggA)
A1122_RS06685	COG1280	lysine exporter protein (LysE YggA)
A1122_RS06690	COG2267	carboxylic ester hydrolase activity
A1122_RS06695	COG0561	phosphatase activity
A1122_RS06705	COG0584	glycerophosphoryl diester phosphodiesterase
A1122_RS06715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A1122_RS06725	COG0247	lactate metabolic process
A1122_RS06735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A1122_RS06750	COG3714	YhhN family
A1122_RS06765	COG3776	membrane
A1122_RS06770	COG0742	ribosomal rna small subunit methyltransferase
A1122_RS06780	COG0552	protein localization to endoplasmic reticulum
A1122_RS06780	COG0552	protein localization to endoplasmic reticulum
A1122_RS06785	COG2884	Cell division ATP-binding protein ftsE
A1122_RS06790	COG2177	Part of the ABC transporter FtsEX involved in
A1122_RS06815	COG0683	leucine binding
A1122_RS06825	COG4177	L-phenylalanine transmembrane transporter activity
A1122_RS06835	COG0410	ABC transporter
A1122_RS06895	COG0584	glycerophosphoryl diester phosphodiesterase
A1122_RS06900	COG0679	Auxin Efflux Carrier
A1122_RS06905	COG0697	spore germination
A1122_RS06910	COG0583	DNA-binding transcription factor activity
A1122_RS06920	COG0412	Dienelactone hydrolase
A1122_RS06935	COG1966	Carbon starvation protein
A1122_RS06940	COG0586	Pfam SNARE associated Golgi protein
A1122_RS06945	COG1322	Protein conserved in bacteria
A1122_RS06965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A1122_RS06975	COG0805	protein transport
A1122_RS07010	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A1122_RS07035	COG1739	Uncharacterized protein family UPF0029
A1122_RS07045	COG1739	Uncharacterized protein family UPF0029
A1122_RS07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A1122_RS07055	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
A1122_RS07090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A1122_RS07150	COG0250	Participates in transcription elongation, termination and antitermination
A1122_RS07205	COG2022	thiamine diphosphate biosynthetic process
A1122_RS07215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A1122_RS07255	COG1515	deoxyribonuclease V activity
A1122_RS07275	COG0151	Belongs to the GarS family
A1122_RS07325	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A1122_RS07330	COG2224	Isocitrate lyase
A1122_RS07340	COG1414	Transcriptional regulator
A1122_RS07345	COG1414	Transcriptional regulator
A1122_RS07365	COG0527	aspartate kinase activity
A1122_RS07380	COG3833	ABC-type maltose transport systems, permease component
A1122_RS07385	COG1175	transmembrane transport
A1122_RS07445	COG2801	Transposase and inactivated derivatives
A1122_RS07520	COG3501	Rhs element vgr protein
A1122_RS07565	COG3501	Rhs element vgr protein
A1122_RS07575	COG3209	COG3209 Rhs family protein
A1122_RS07590	COG0673	inositol 2-dehydrogenase activity
A1122_RS07595	COG2207	Transcriptional regulator
A1122_RS07595	COG1917	Cupin 2, conserved barrel domain protein
A1122_RS07600	COG1869	D-ribose catabolic process
A1122_RS07605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_RS07610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A1122_RS07615	COG0431	NADPH-dependent FMN reductase
A1122_RS07620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A1122_RS07630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1122_RS07640	COG3077	Addiction module antitoxin, RelB DinJ family
A1122_RS07645	COG2252	PERMEase
A1122_RS07650	COG0025	NhaP-type Na H and K H
A1122_RS07660	COG1560	Kdo2-lipid A biosynthetic process
A1122_RS07670	COG1129	ABC transporter
A1122_RS07675	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS07685	COG1069	ribulokinase activity
A1122_RS07695	COG0625	glutathione transferase activity
A1122_RS07720	COG1278	Cold shock
A1122_RS07725	COG1278	Cold shock
A1122_RS07735	COG3133	Outer membrane lipoprotein
A1122_RS07740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1122_RS07750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1122_RS07770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A1122_RS07775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1122_RS07785	COG4145	pantothenate transmembrane transporter activity
A1122_RS07790	COG3924	membrane
A1122_RS07795	COG0439	Biotin carboxylase
A1122_RS07800	COG0511	ligase activity, forming carbon-carbon bonds
A1122_RS07815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A1122_RS07820	COG0604	alcohol dehydrogenase
A1122_RS07825	COG2199	diguanylate cyclase activity
A1122_RS07825	COG2200	EAL domain
A1122_RS07830	COG1077	Cell shape determining protein MreB Mrl
A1122_RS07835	COG1792	Involved in formation and maintenance of cell shape
A1122_RS07840	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A1122_RS07845	COG0424	maF-like protein
A1122_RS07850	COG1530	ribonuclease E activity
A1122_RS07855	COG3164	Protein of unknown function
A1122_RS07860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1122_RS07865	COG0312	modulator of DNA gyrase
A1122_RS07925	COG0583	DNA-binding transcription factor activity
A1122_RS07945	COG1012	belongs to the aldehyde dehydrogenase family
A1122_RS07960	COG2732	(Barnase) inhibitor
A1122_RS07970	COG0312	modulator of DNA gyrase
A1122_RS07980	COG3783	Cytochrome b(562)
A1122_RS07985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A1122_RS07990	COG0366	Alpha amylase catalytic
A1122_RS07995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_RS07995	COG1263	PTS System
A1122_RS08000	COG1609	Transcriptional regulator
A1122_RS08035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS08055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A1122_RS08060	COG1137	ATPase activity
A1122_RS08065	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A1122_RS08070	COG3117	lipopolysaccharide transmembrane transporter activity
A1122_RS08075	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A1122_RS08080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A1122_RS08080	COG0517	IMP dehydrogenase activity
A1122_RS08085	COG0530	calcium, potassium:sodium antiporter activity
A1122_RS08090	COG1127	ABC transporter
A1122_RS08095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A1122_RS08100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A1122_RS08105	COG2854	intermembrane phospholipid transfer
A1122_RS08110	COG3113	response to antibiotic
A1122_RS08115	COG5007	Belongs to the BolA IbaG family
A1122_RS08125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1122_RS08135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1122_RS08140	COG3105	Protein conserved in bacteria
A1122_RS08145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A1122_RS08165	COG0625	glutathione transferase activity
A1122_RS08170	COG2969	positive regulation of protein catabolic process
A1122_RS08180	COG0493	'glutamate synthase
A1122_RS08185	COG0070	glutamate synthase
A1122_RS08185	COG0069	glutamate synthase activity
A1122_RS08185	COG0067	glutamate synthase
A1122_RS08190	COG1242	4 iron, 4 sulfur cluster binding
A1122_RS08200	COG5002	protein histidine kinase activity
A1122_RS08200	COG0784	Response regulator, receiver
A1122_RS08200	COG2198	Histidine kinase
A1122_RS08210	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
A1122_RS08220	COG2823	Periplasmic or secreted lipoprotein
A1122_RS08240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A1122_RS08245	COG1741	Belongs to the pirin family
A1122_RS08250	COG0583	DNA-binding transcription factor activity
A1122_RS08255	COG0435	Glutathione S-transferase
A1122_RS08270	COG1073	alpha beta
A1122_RS08280	COG0360	Binds together with S18 to 16S ribosomal RNA
A1122_RS08290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A1122_RS08315	COG3061	Opacity-associated protein A
A1122_RS08320	COG0545	Peptidyl-prolyl cis-trans isomerase
A1122_RS08330	COG0737	Belongs to the 5'-nucleotidase family
A1122_RS08340	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
A1122_RS08350	COG1253	flavin adenine dinucleotide binding
A1122_RS08360	COG0729	surface antigen
A1122_RS08365	COG2911	Protein conserved in bacteria
A1122_RS08370	COG2105	PFAM AIG2 family protein
A1122_RS08375	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A1122_RS08380	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
A1122_RS08385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A1122_RS08410	COG3423	Transcriptional regulator
A1122_RS08420	COG0142	geranyltranstransferase activity
A1122_RS08435	COG0697	spore germination
A1122_RS08445	COG0642	Histidine kinase
A1122_RS08450	COG0745	RESPONSE REGULATOR receiver
A1122_RS08455	COG2027	D-alanyl-D-alanine carboxypeptidase
A1122_RS08465	COG1534	Rna-binding protein
A1122_RS08480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A1122_RS08490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A1122_RS08510	COG0195	Participates in both transcription termination and antitermination
A1122_RS08540	COG2801	Transposase and inactivated derivatives
A1122_RS08555	COG0513	Belongs to the DEAD box helicase family
A1122_RS08575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A1122_RS08585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_RS08595	COG0826	peptidase U32
A1122_RS08600	COG0826	peptidase U32
A1122_RS08610	COG3154	lipid carrier protein
A1122_RS08615	COG3153	acetyltransferase
A1122_RS08635	COG1653	transport
A1122_RS08640	COG1175	transmembrane transport
A1122_RS08645	COG0395	ABC-type sugar transport system, permease component
A1122_RS08650	COG3842	ATPase activity
A1122_RS08665	COG0702	epimerase
A1122_RS08670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A1122_RS08675	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
A1122_RS08680	COG3454	Phosphonate metabolism
A1122_RS08685	COG4778	phosphonate C-P lyase system protein PhnL
A1122_RS08690	COG4107	phosphonate C-P lyase system protein PhnK
A1122_RS08695	COG3627	carbon phosphorus lyase activity
A1122_RS08700	COG3626	phosphonate metabolism
A1122_RS08705	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A1122_RS08710	COG3624	Phosphonate C-P lyase system protein PhnG
A1122_RS08715	COG2188	Transcriptional regulator
A1122_RS08730	COG4608	Belongs to the ABC transporter superfamily
A1122_RS08735	COG0444	Belongs to the ABC transporter superfamily
A1122_RS08740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_RS08745	COG0601	transmembrane transport
A1122_RS08755	COG2731	YhcH YjgK YiaL family protein
A1122_RS08765	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
A1122_RS08775	COG0525	valine-tRNA ligase activity
A1122_RS08780	COG2927	DNA polymerase III (CHI subunit)
A1122_RS08790	COG0795	lipopolysaccharide-transporting ATPase activity
A1122_RS08795	COG0795	lipopolysaccharide-transporting ATPase activity
A1122_RS08805	COG0582	viral genome integration into host DNA
A1122_RS08860	COG1459	type II secretion system
A1122_RS08865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A1122_RS08870	COG4969	Belongs to the N-Me-Phe pilin family
A1122_RS08880	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1122_RS08885	COG3725	Membrane protein required for beta-lactamase induction
A1122_RS08890	COG1113	amino acid transport
A1122_RS08895	COG2186	Transcriptional regulator
A1122_RS08900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
A1122_RS08905	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1122_RS08910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A1122_RS08925	COG1049	propionate catabolic process, 2-methylcitrate cycle
A1122_RS08935	COG0697	spore germination
A1122_RS08955	COG2132	Multicopper oxidase
A1122_RS08960	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A1122_RS08965	COG0288	reversible hydration of carbon dioxide
A1122_RS08970	COG1131	(ABC) transporter
A1122_RS08975	COG0842	Transport permease protein
A1122_RS08980	COG0726	polysaccharide deacetylase
A1122_RS09000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A1122_RS09005	COG0617	tRNA 3'-terminal CCA addition
A1122_RS09010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A1122_RS09025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A1122_RS09030	COG1643	Atp-dependent helicase
A1122_RS09035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A1122_RS09040	COG1120	ATPase activity
A1122_RS09045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1122_RS09050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_RS09070	COG2860	membrane
A1122_RS09090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A1122_RS09095	COG3437	response regulator, receiver
A1122_RS09095	COG3850	Histidine kinase
A1122_RS09095	COG4999	Histidine kinase
A1122_RS09095	COG2205	protein histidine kinase activity
A1122_RS09100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A1122_RS09110	COG3956	TIGRFAM MazG family protein
A1122_RS09130	COG0602	queuosine metabolic process
A1122_RS09135	COG0720	synthase
A1122_RS09185	COG0529	Catalyzes the synthesis of activated sulfate
A1122_RS09225	COG1388	LysM domain
A1122_RS09225	COG4942	peptidase
A1122_RS09230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A1122_RS09245	COG0698	ribose 5-phosphate isomerase
A1122_RS09250	COG1063	alcohol dehydrogenase
A1122_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS09260	COG2376	Dihydroxyacetone kinase
A1122_RS09275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A1122_RS09295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS09300	COG1858	cytochrome C peroxidase
A1122_RS09310	COG4771	TonB-dependent receptor
A1122_RS09330	COG0024	Methionine aminopeptidase
A1122_RS09340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A1122_RS09340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A1122_RS09345	COG1070	Carbohydrate kinase
A1122_RS09350	COG3623	hexulose-6-phosphate isomerase
A1122_RS09355	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS09360	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS09365	COG1129	ABC transporter
A1122_RS09380	COG1349	DNA-binding transcription factor activity
A1122_RS09385	COG0235	Class ii aldolase
A1122_RS09390	COG0243	molybdopterin cofactor binding
A1122_RS09395	COG0437	4 iron, 4 sulfur cluster binding
A1122_RS09400	COG3302	dmso reductase anchor subunit
A1122_RS09405	COG3381	protein complex oligomerization
A1122_RS09410	COG3038	cytochrome b561
A1122_RS09415	COG3783	Cytochrome b(562)
A1122_RS09425	COG1879	ABC-type sugar transport system periplasmic component
A1122_RS09435	COG1129	ABC transporter
A1122_RS09440	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS09445	COG3959	Transketolase, thiamine diphosphate binding domain
A1122_RS09450	COG3958	Transketolase
A1122_RS09455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A1122_RS09495	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
A1122_RS09520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_RS09525	COG1238	metal cluster binding
A1122_RS09530	COG2918	glutathione biosynthetic process
A1122_RS09560	COG4536	flavin adenine dinucleotide binding
A1122_RS09575	COG4536	flavin adenine dinucleotide binding
A1122_RS09580	COG4137	Cytochrome C assembly protein
A1122_RS09585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A1122_RS09620	COG3137	Salt-induced outer membrane protein
A1122_RS09625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1122_RS09630	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1122_RS09635	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A1122_RS09640	COG3279	Response regulator of the LytR AlgR family
A1122_RS09645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1122_RS09650	COG0287	Prephenate dehydrogenase
A1122_RS09650	COG1605	Chorismate mutase
A1122_RS09655	COG1605	Chorismate mutase
A1122_RS09655	COG0077	Prephenate dehydratase
A1122_RS09670	COG1605	Chorismate mutase
A1122_RS09670	COG0077	Prephenate dehydratase
A1122_RS09680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A1122_RS09685	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1122_RS09690	COG0564	pseudouridine synthase activity
A1122_RS09700	COG0542	response to heat
A1122_RS09740	COG5544	Lipoprotein
A1122_RS09745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A1122_RS09750	COG1042	CoA-binding domain protein
A1122_RS09750	COG0045	succinate-CoA ligase (ADP-forming) activity
A1122_RS09750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1122_RS09755	COG3148	PFAM DTW domain containing protein
A1122_RS09760	COG3118	belongs to the thioredoxin family
A1122_RS09765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A1122_RS09770	COG2814	Major facilitator Superfamily
A1122_RS09775	COG1566	PFAM secretion protein HlyD family protein
A1122_RS09780	COG1846	Transcriptional regulator
A1122_RS09790	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A1122_RS09795	COG2814	Major facilitator Superfamily
A1122_RS09835	COG0765	amino acid transport
A1122_RS09845	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A1122_RS09860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A1122_RS09880	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
A1122_RS09890	COG1960	acyl-CoA dehydrogenase activity
A1122_RS09900	COG0121	glutamine amidotransferase
A1122_RS09905	COG3034	peptidoglycan biosynthetic process
A1122_RS09915	COG1805	sodium ion transport
A1122_RS09920	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
A1122_RS09940	COG1477	protein flavinylation
A1122_RS09960	COG2195	Cleaves the N-terminal amino acid of tripeptides
A1122_RS10020	COG2226	methyltransferase
A1122_RS10055	COG1940	carbohydrate kinase activity
A1122_RS10070	COG0419	ATPase involved in DNA repair
A1122_RS10075	COG0420	3'-5' exonuclease activity
A1122_RS10085	COG0745	RESPONSE REGULATOR receiver
A1122_RS10090	COG5002	protein histidine kinase activity
A1122_RS10110	COG0366	Alpha amylase catalytic
A1122_RS10140	COG0450	alkyl hydroperoxide reductase
A1122_RS10160	COG1862	Preprotein translocase
A1122_RS10165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1122_RS10170	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A1122_RS10195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1122_RS10195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A1122_RS10210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A1122_RS10215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A1122_RS10235	COG0142	geranyltranstransferase activity
A1122_RS10255	COG0693	protein deglycase activity
A1122_RS10260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A1122_RS10270	COG2814	Major facilitator Superfamily
A1122_RS10280	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A1122_RS10285	COG1845	cytochrome c oxidase, subunit III
A1122_RS10290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A1122_RS10295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A1122_RS10305	COG2223	nitrite transmembrane transporter activity
A1122_RS10310	COG3056	Lipoprotein
A1122_RS10315	COG0271	Belongs to the BolA IbaG family
A1122_RS10340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A1122_RS10345	COG0776	regulation of translation
A1122_RS10350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A1122_RS10355	COG1555	photosystem II stabilization
A1122_RS10360	COG0824	Thioesterase
A1122_RS10370	COG4533	DNA binding
A1122_RS10385	COG1522	sequence-specific DNA binding
A1122_RS10390	COG1132	(ABC) transporter
A1122_RS10395	COG1132	(ABC) transporter
A1122_RS10400	COG0347	Belongs to the P(II) protein family
A1122_RS10405	COG0004	ammonium transporteR
A1122_RS10410	COG1946	Acyl-CoA thioesterase
A1122_RS10415	COG3126	Type III secretion system lipoprotein chaperone (YscW)
A1122_RS10420	COG3695	enzyme binding
A1122_RS10440	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A1122_RS10450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_RS10455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_RS10460	COG1309	transcriptional regulator
A1122_RS10465	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A1122_RS10470	COG1196	nuclear chromosome segregation
A1122_RS10470	COG3264	Mechanosensitive ion channel
A1122_RS10485	COG2832	Protein of unknown function (DUF454)
A1122_RS10505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A1122_RS10535	COG0543	2 iron, 2 sulfur cluster binding
A1122_RS10535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_RS10560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_RS10620	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
A1122_RS10625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_RS10630	COG4651	solute:proton antiporter activity
A1122_RS10630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A1122_RS10635	COG2223	nitrite transmembrane transporter activity
A1122_RS10640	COG0737	Belongs to the 5'-nucleotidase family
A1122_RS10645	COG0737	Belongs to the 5'-nucleotidase family
A1122_RS10650	COG0737	Belongs to the 5'-nucleotidase family
A1122_RS10665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A1122_RS10670	COG3735	TraB family
A1122_RS10675	COG2217	Heavy metal translocating P-type atpase
A1122_RS10680	COG0789	Transcriptional regulator
A1122_RS10685	COG1585	Membrane protein implicated in regulation of membrane protease activity
A1122_RS10690	COG0330	HflC and HflK could
A1122_RS10695	COG3118	belongs to the thioredoxin family
A1122_RS10700	COG0300	oxidoreductase activity
A1122_RS10705	COG2755	lipolytic protein G-D-S-L family
A1122_RS10710	COG4181	ATPase activity
A1122_RS10715	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A1122_RS10720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A1122_RS10725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A1122_RS10735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A1122_RS10760	COG1393	Belongs to the ArsC family
A1122_RS10765	COG4783	chaperone-mediated protein folding
A1122_RS10770	COG0628	permease
A1122_RS10790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A1122_RS10795	COG2716	regulation of RNA biosynthetic process
A1122_RS10805	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
A1122_RS10825	COG2321	neutral zinc metallopeptidase
A1122_RS10845	COG1876	peptidase activity
A1122_RS10855	COG1393	Belongs to the ArsC family
A1122_RS10870	COG1175	transmembrane transport
A1122_RS10875	COG3842	ATPase activity
A1122_RS10880	COG3119	arylsulfatase activity
A1122_RS10885	COG0641	radical SAM
A1122_RS10890	COG1988	membrane-bound metal-dependent
A1122_RS10900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A1122_RS10910	COG2197	response regulator
A1122_RS10915	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_RS10915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_RS10920	COG3062	negative regulation of establishment of protein localization
A1122_RS10930	COG3043	anaerobic respiration
A1122_RS10935	COG3005	denitrification pathway
A1122_RS10980	COG3111	PFAM Bacterial OB fold (BOF) protein
A1122_RS10990	COG2837	iron assimilation
A1122_RS10995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A1122_RS11005	COG4886	Leucine-rich repeat (LRR) protein
A1122_RS11015	COG2731	YhcH YjgK YiaL family protein
A1122_RS11025	COG1737	Transcriptional regulator
A1122_RS11035	COG4150	thiosulfate binding
A1122_RS11040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A1122_RS11045	COG4208	sulfate ABC transporter
A1122_RS11050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A1122_RS11065	COG0745	RESPONSE REGULATOR receiver
A1122_RS11070	COG5002	protein histidine kinase activity
A1122_RS11070	COG3850	Histidine kinase
A1122_RS11080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A1122_RS11100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A1122_RS11115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_RS11120	COG0745	RESPONSE REGULATOR receiver
A1122_RS11125	COG2205	protein histidine kinase activity
A1122_RS11150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS11160	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
A1122_RS11175	COG3530	Putative quorum-sensing-regulated virulence factor
A1122_RS11230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A1122_RS11245	COG0667	Aldo Keto reductase
A1122_RS11270	COG0436	Aminotransferase
A1122_RS11275	COG3038	cytochrome b561
A1122_RS11305	COG3381	protein complex oligomerization
A1122_RS11310	COG3302	dmso reductase anchor subunit
A1122_RS11315	COG0437	4 iron, 4 sulfur cluster binding
A1122_RS11320	COG0243	molybdopterin cofactor binding
A1122_RS11355	COG2951	lytic endotransglycosylase activity
A1122_RS11415	COG3121	Chaperone
A1122_RS11420	COG3188	usher protein
A1122_RS11425	COG3328	transposase activity
A1122_RS11430	COG3188	usher protein
A1122_RS11490	COG0671	phosphoesterase, PA-phosphatase related
A1122_RS11490	COG2453	phosphatase
A1122_RS11495	COG2267	carboxylic ester hydrolase activity
A1122_RS11505	COG4589	Belongs to the CDS family
A1122_RS11510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A1122_RS11560	COG2501	S4 domain
A1122_RS11580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A1122_RS11585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1122_RS11605	COG0581	inorganic phosphate transmembrane transporter activity
A1122_RS11615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A1122_RS11630	COG2239	Acts as a magnesium transporter
A1122_RS11635	COG0443	Heat shock 70 kDa protein
A1122_RS11640	COG1177	transmembrane transport
A1122_RS11645	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1122_RS11655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A1122_RS11665	COG3842	ATPase activity
A1122_RS11690	COG2205	protein histidine kinase activity
A1122_RS11695	COG2205	protein histidine kinase activity
A1122_RS11700	COG0745	RESPONSE REGULATOR receiver
A1122_RS11705	COG3422	double-strand break repair
A1122_RS11710	COG0826	peptidase U32
A1122_RS11730	COG0351	phosphomethylpyrimidine kinase
A1122_RS11745	COG3328	transposase activity
A1122_RS11800	COG0517	IMP dehydrogenase activity
A1122_RS11800	COG0516	GMP reductase activity
A1122_RS11810	COG1645	bacterial-type flagellum-dependent swarming motility
A1122_RS11835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1122_RS11840	COG2976	Protein conserved in bacteria
A1122_RS11885	COG3468	outer membrane autotransporter barrel domain protein
A1122_RS11890	COG3468	outer membrane autotransporter barrel domain protein
A1122_RS11910	COG2975	iron-sulfur cluster assembly
A1122_RS11915	COG0633	Ferredoxin
A1122_RS11920	COG0443	Heat shock 70 kDa protein
A1122_RS11935	COG0822	iron-sulfur transferase activity
A1122_RS11940	COG1104	cysteine desulfurase activity
A1122_RS11965	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A1122_RS11970	COG3683	transport system, periplasmic component
A1122_RS11975	COG3711	transcriptional antiterminator
A1122_RS11980	COG2814	Major facilitator Superfamily
A1122_RS12000	COG1017	nitric oxide dioxygenase activity
A1122_RS12000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_RS12005	COG2188	Transcriptional regulator
A1122_RS12010	COG2188	Transcriptional regulator
A1122_RS12015	COG0347	Belongs to the P(II) protein family
A1122_RS12020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A1122_RS12020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A1122_RS12025	COG2204	response regulator
A1122_RS12030	COG3170	Tfp pilus assembly protein FimV
A1122_RS12035	COG2205	protein histidine kinase activity
A1122_RS12075	COG0560	Phosphoserine phosphatase
A1122_RS12085	COG1737	Transcriptional regulator
A1122_RS12090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A1122_RS12110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A1122_RS12135	COG0667	Aldo Keto reductase
A1122_RS12140	COG0656	L-ascorbic acid biosynthetic process
A1122_RS12160	COG1472	Belongs to the glycosyl hydrolase 3 family
A1122_RS12175	COG3328	transposase activity
A1122_RS12180	COG2850	peptidyl-arginine hydroxylation
A1122_RS12230	COG3423	Transcriptional regulator
A1122_RS12235	COG4953	penicillin-binding protein 1C
A1122_RS12240	COG3328	transposase activity
A1122_RS12245	COG3037	sugar-specific permease SgaT UlaA
A1122_RS12250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A1122_RS12255	COG0622	Phosphoesterase
A1122_RS12265	COG1090	epimerase
A1122_RS12270	COG4598	ABC transporter
A1122_RS12275	COG4160	amino acid transport
A1122_RS12280	COG4215	(ABC) transporter
A1122_RS12285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS12295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A1122_RS12300	COG1286	toxin biosynthetic process
A1122_RS12305	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
A1122_RS12310	COG0285	dihydrofolate synthase activity
A1122_RS12320	COG0586	Pfam SNARE associated Golgi protein
A1122_RS12330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A1122_RS12355	COG0697	spore germination
A1122_RS12370	COG1794	racemase activity, acting on amino acids and derivatives
A1122_RS12375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_RS12390	COG3101	peptidyl-lysine hydroxylation
A1122_RS12395	COG0730	response to heat
A1122_RS12400	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
A1122_RS12410	COG2890	protein-(glutamine-N5) methyltransferase activity
A1122_RS12420	COG2062	phosphohistidine phosphatase, SixA
A1122_RS12435	COG3691	Protein conserved in bacteria
A1122_RS12450	COG3088	subunit of a heme lyase
A1122_RS12450	COG4235	cytochrome complex assembly
A1122_RS12455	COG3088	subunit of a heme lyase
A1122_RS12455	COG4235	cytochrome complex assembly
A1122_RS12460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A1122_RS12465	COG1138	Cytochrome C-type biogenesis protein
A1122_RS12475	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1122_RS12480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1122_RS12485	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A1122_RS12505	COG1704	LemA family
A1122_RS12515	COG2824	Alkylphosphonate utilization operon protein PhnA
A1122_RS12600	COG3086	response to oxidative stress
A1122_RS12605	COG3026	antisigma factor binding
A1122_RS12620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A1122_RS12630	COG0513	Belongs to the DEAD box helicase family
A1122_RS12680	COG1984	allophanate hydrolase subunit 2
A1122_RS12690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A1122_RS12695	COG5212	phosphodiesterase
A1122_RS12705	COG3272	Protein of unknown function (DUF1722)
A1122_RS12740	COG2205	protein histidine kinase activity
A1122_RS12745	COG0745	RESPONSE REGULATOR receiver
A1122_RS12765	COG0033	Phosphoglucomutase
A1122_RS12770	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
A1122_RS12790	COG1917	Cupin 2, conserved barrel domain protein
A1122_RS12790	COG2169	Transcriptional regulator
A1122_RS12795	COG1447	Phosphotransferase system cellobiose-specific component IIA
A1122_RS12800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1122_RS12805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A1122_RS12815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1122_RS12825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A1122_RS12840	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A1122_RS12845	COG4413	Urea transporter
A1122_RS12855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A1122_RS12880	COG0831	urea catabolic process
A1122_RS12885	COG1124	(ABC) transporter
A1122_RS12890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A1122_RS12895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_RS12905	COG0747	negative chemotaxis
A1122_RS12910	COG1278	Cold shock
A1122_RS12920	COG3328	transposase activity
A1122_RS12955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A1122_RS12960	COG4175	Glycine betaine
A1122_RS12965	COG4176	ABC-type proline glycine betaine transport system permease component
A1122_RS12970	COG2113	Glycine betaine
A1122_RS12990	COG0582	viral genome integration into host DNA
A1122_RS12995	COG2963	transposase activity
A1122_RS13000	COG0582	viral genome integration into host DNA
A1122_RS13010	COG0596	Alpha beta hydrolase
A1122_RS13030	COG0735	belongs to the Fur family
A1122_RS13055	COG1263	PTS System
A1122_RS13055	COG2190	(PTS) system
A1122_RS13055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_RS13065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A1122_RS13070	COG1846	Transcriptional regulator
A1122_RS13070	COG1940	carbohydrate kinase activity
A1122_RS13075	COG0647	UMP catabolic process
A1122_RS13080	COG0367	asparagine synthase
A1122_RS13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A1122_RS13120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A1122_RS13125	COG1702	phosphate starvation-inducible protein PhoH
A1122_RS13135	COG4535	Mg2 and Co2 transporter CorC
A1122_RS13140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A1122_RS13150	COG0765	amino acid transport
A1122_RS13155	COG0765	amino acid transport
A1122_RS13160	COG1126	abc transporter atp-binding protein
A1122_RS13165	COG2888	peptidyl-tyrosine sulfation
A1122_RS13180	COG1466	dna polymerase III delta subunit
A1122_RS13190	COG0799	negative regulation of ribosome biogenesis
A1122_RS13200	COG0768	penicillin binding
A1122_RS13205	COG0772	Belongs to the SEDS family
A1122_RS13210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A1122_RS13215	COG1686	Belongs to the peptidase S11 family
A1122_RS13235	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A1122_RS13245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A1122_RS13260	COG2197	response regulator
A1122_RS13285	COG5265	(ABC) transporter
A1122_RS13295	COG3718	enzyme involved in inositol metabolism
A1122_RS13305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_RS13310	COG0673	inositol 2-dehydrogenase activity
A1122_RS13315	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS13320	COG1129	ABC transporter
A1122_RS13335	COG3962	Belongs to the TPP enzyme family
A1122_RS13355	COG2373	Large extracellular alpha-helical protein
A1122_RS13360	COG4953	penicillin-binding protein 1C
A1122_RS13365	COG3328	transposase activity
A1122_RS13380	COG1609	Transcriptional regulator
A1122_RS13385	COG0857	belongs to the CobB CobQ family
A1122_RS13385	COG0280	phosphate acetyltransferase
A1122_RS13410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_RS13415	COG0490	domain, Protein
A1122_RS13415	COG0471	metal ion transport
A1122_RS13430	COG0436	Aminotransferase
A1122_RS13440	COG0583	DNA-binding transcription factor activity
A1122_RS13450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1122_RS13470	COG1034	ATP synthesis coupled electron transport
A1122_RS13485	COG0839	Belongs to the complex I subunit 6 family
A1122_RS13495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A1122_RS13500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1122_RS13515	COG2731	YhcH YjgK YiaL family protein
A1122_RS13520	COG3265	gluconokinase activity
A1122_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS13530	COG1649	PFAM Uncharacterised BCR, COG1649
A1122_RS13535	COG1609	Transcriptional regulator
A1122_RS13545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1122_RS13560	COG0129	dihydroxy-acid dehydratase activity
A1122_RS13575	COG4575	ribosome binding
A1122_RS13585	COG1169	isochorismate synthase
A1122_RS13600	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A1122_RS13615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A1122_RS13650	COG1126	abc transporter atp-binding protein
A1122_RS13655	COG0765	amino acid transport
A1122_RS13660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS13690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A1122_RS13710	COG1063	alcohol dehydrogenase
A1122_RS13715	COG1879	ABC-type sugar transport system periplasmic component
A1122_RS13720	COG1129	ABC transporter
A1122_RS13725	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS13730	COG1609	Transcriptional regulator
A1122_RS13735	COG0583	DNA-binding transcription factor activity
A1122_RS13740	COG0473	3-isopropylmalate dehydrogenase activity
A1122_RS13750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A1122_RS13755	COG4638	Rieske (2fe-2S)
A1122_RS13760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_RS13765	COG2831	hemolysin activation secretion protein
A1122_RS13770	COG3210	domain, Protein
A1122_RS13790	COG3210	domain, Protein
A1122_RS13810	COG3210	domain, Protein
A1122_RS13820	COG3842	ATPase activity
A1122_RS13830	COG1609	Transcriptional regulator
A1122_RS13845	COG0395	ABC-type sugar transport system, permease component
A1122_RS13850	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
A1122_RS13870	COG0668	transmembrane transport
A1122_RS13875	COG1518	maintenance of DNA repeat elements
A1122_RS13880	COG1203	CRISPR-associated helicase, Cas3
A1122_RS13910	COG0667	Aldo Keto reductase
A1122_RS13920	COG0477	Major facilitator Superfamily
A1122_RS13930	COG0583	DNA-binding transcription factor activity
A1122_RS13935	COG2771	luxR family
A1122_RS13940	COG3916	Acyl-homoserine-lactone synthase
A1122_RS13970	COG0628	permease
A1122_RS13985	COG3328	transposase activity
A1122_RS13990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A1122_RS14000	COG3001	Fructosamine kinase
A1122_RS14010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1122_RS14015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1122_RS14020	COG1121	(ABC) transporter
A1122_RS14025	COG0803	Belongs to the bacterial solute-binding protein 9 family
A1122_RS14050	COG4249	Peptidase C14 caspase catalytic subunit p20
A1122_RS14080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A1122_RS14080	COG0072	phenylalanine-tRNA ligase activity
A1122_RS14085	COG0776	regulation of translation
A1122_RS14100	COG0386	Belongs to the glutathione peroxidase family
A1122_RS14145	COG0791	NLP P60 protein
A1122_RS14170	COG0574	Belongs to the PEP-utilizing enzyme family
A1122_RS14170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A1122_RS14175	COG0628	permease
A1122_RS14180	COG0247	lactate metabolic process
A1122_RS14180	COG0277	FAD linked oxidase domain protein
A1122_RS14185	COG2050	protein possibly involved in aromatic compounds catabolism
A1122_RS14195	COG0316	Belongs to the HesB IscA family
A1122_RS14200	COG0719	Fe-S assembly protein
A1122_RS14205	COG0396	ATPase activity
A1122_RS14210	COG0719	Fe-S assembly protein
A1122_RS14225	COG1388	LysM domain
A1122_RS14225	COG1376	ErfK ybiS ycfS ynhG family protein
A1122_RS14275	COG0307	riboflavin synthase, alpha
A1122_RS14280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A1122_RS14285	COG2814	Major facilitator Superfamily
A1122_RS14290	COG0583	DNA-binding transcription factor activity
A1122_RS14305	COG0791	NLP P60 protein
A1122_RS14315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A1122_RS14320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A1122_RS14325	COG0346	lactoylglutathione lyase activity
A1122_RS14335	COG1902	pentaerythritol trinitrate reductase activity
A1122_RS14340	COG1309	transcriptional regulator
A1122_RS14345	COG2194	sulfuric ester hydrolase activity
A1122_RS14350	COG3313	Fe-S protein
A1122_RS14355	COG4989	oxidoreductase activity
A1122_RS14365	COG3133	Outer membrane lipoprotein
A1122_RS14375	COG3895	Periplasmic Protein
A1122_RS14395	COG0625	glutathione transferase activity
A1122_RS14420	COG3104	oligopeptide transport
A1122_RS14425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1122_RS14425	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A1122_RS14430	COG4172	Belongs to the ABC transporter superfamily
A1122_RS14440	COG4171	peptide transport system, permease
A1122_RS14445	COG4168	peptide transport system, permease
A1122_RS14450	COG4166	transmembrane transport
A1122_RS14470	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A1122_RS14475	COG1842	Phage shock protein A
A1122_RS14485	COG1983	PspC domain protein
A1122_RS14495	COG3106	COG3106 Predicted ATPase
A1122_RS14505	COG5654	RES domain protein
A1122_RS14510	COG5642	Protein of unknown function (DUF2384)
A1122_RS14525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A1122_RS14530	COG4948	Mandelate Racemase Muconate Lactonizing
A1122_RS14535	COG2866	Carboxypeptidase
A1122_RS14540	COG4166	transmembrane transport
A1122_RS14555	COG0657	acetylesterase activity
A1122_RS14565	COG0674	pyruvate-flavodoxin oxidoreductase activity
A1122_RS14565	COG1013	pyruvate-flavodoxin oxidoreductase activity
A1122_RS14565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A1122_RS14565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A1122_RS14575	COG1285	pathogenesis
A1122_RS14580	COG3042	response to heat
A1122_RS14585	COG3187	Heat shock protein
A1122_RS14590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A1122_RS14595	COG2911	Protein conserved in bacteria
A1122_RS14605	COG3784	Protein of unknown function (DUF1318)
A1122_RS14610	COG0246	Mannitol dehydrogenase
A1122_RS14615	COG2390	Transcriptional regulator
A1122_RS14625	COG1643	Atp-dependent helicase
A1122_RS14640	COG3591	Belongs to the peptidase S1B family
A1122_RS14655	COG3038	cytochrome b561
A1122_RS14690	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A1122_RS14695	COG2205	protein histidine kinase activity
A1122_RS14700	COG0745	RESPONSE REGULATOR receiver
A1122_RS14710	COG0531	amino acid
A1122_RS14725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A1122_RS14730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A1122_RS14735	COG0589	response to stress
A1122_RS14740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A1122_RS14745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A1122_RS14765	COG1011	Hydrolase
A1122_RS14770	COG0440	acetolactate synthase activity
A1122_RS14775	COG0028	Belongs to the TPP enzyme family
A1122_RS14800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A1122_RS14805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A1122_RS14825	COG1609	Transcriptional regulator
A1122_RS14845	COG4128	Pfam Zonular occludens toxin
A1122_RS14895	COG0038	chloride channel
A1122_RS14900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A1122_RS14905	COG1940	carbohydrate kinase activity
A1122_RS14925	COG0114	fumarate hydratase activity
A1122_RS14935	COG5339	Protein conserved in bacteria
A1122_RS14945	COG0385	Bile acid
A1122_RS14950	COG0673	inositol 2-dehydrogenase activity
A1122_RS14960	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS14965	COG1129	ABC transporter
A1122_RS14970	COG1879	ABC-type sugar transport system periplasmic component
A1122_RS14985	COG2274	protein secretion by the type I secretion system
A1122_RS14990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_RS15000	COG1132	(ABC) transporter
A1122_RS15030	COG3708	Transcriptional regulator
A1122_RS15030	COG2207	Transcriptional regulator
A1122_RS15035	COG4658	electron transport chain
A1122_RS15040	COG4659	FMN binding
A1122_RS15050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A1122_RS15055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_RS15060	COG2271	Major facilitator Superfamily
A1122_RS15070	COG1966	Carbon starvation protein
A1122_RS15075	COG2879	small protein
A1122_RS15080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A1122_RS15100	COG0023	Translation Initiation Factor
A1122_RS15115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
A1122_RS15120	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
A1122_RS15125	COG0671	phosphoesterase, PA-phosphatase related
A1122_RS15135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A1122_RS15145	COG0583	DNA-binding transcription factor activity
A1122_RS15165	COG0616	signal peptide processing
A1122_RS15170	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS15180	COG1187	pseudouridine synthase activity
A1122_RS15185	COG0009	L-threonylcarbamoyladenylate synthase
A1122_RS15210	COG0512	Glutamine amidotransferase of anthranilate synthase
A1122_RS15220	COG0135	phosphoribosylanthranilate isomerase activity
A1122_RS15220	COG0134	indole-3-glycerol-phosphate synthase activity
A1122_RS15240	COG3047	cAMP biosynthetic process
A1122_RS15275	COG3328	transposase activity
A1122_RS15280	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A1122_RS15285	COG2350	Protein conserved in bacteria
A1122_RS15320	COG4608	Belongs to the ABC transporter superfamily
A1122_RS15325	COG0444	Belongs to the ABC transporter superfamily
A1122_RS15330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A1122_RS15335	COG0601	transmembrane transport
A1122_RS15345	COG2095	MarC family integral membrane protein
A1122_RS15350	COG1012	belongs to the aldehyde dehydrogenase family
A1122_RS15350	COG1454	alcohol dehydrogenase
A1122_RS15370	COG2916	Histone family protein nucleoid-structuring protein H-NS
A1122_RS15380	COG0745	RESPONSE REGULATOR receiver
A1122_RS15390	COG0788	formyltetrahydrofolate deformylase activity
A1122_RS15395	COG3328	transposase activity
A1122_RS15405	COG0583	DNA-binding transcription factor activity
A1122_RS15410	COG0708	Exodeoxyribonuclease III
A1122_RS15415	COG0494	nUDIX hydrolase
A1122_RS15425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A1122_RS15430	COG0709	Synthesizes selenophosphate from selenide and ATP
A1122_RS15435	COG0778	Nitroreductase
A1122_RS15440	COG0616	signal peptide processing
A1122_RS15445	COG0252	asparaginase activity
A1122_RS15450	COG1335	isochorismatase
A1122_RS15455	COG3139	Protein of unknown function (DUF1315)
A1122_RS15475	COG3713	MltA-interacting MipA family protein
A1122_RS15480	COG2766	serine protein kinase
A1122_RS15495	COG0583	DNA-binding transcription factor activity
A1122_RS15505	COG2814	Major facilitator Superfamily
A1122_RS15515	COG2719	SpoVR family
A1122_RS15545	COG1104	cysteine desulfurase activity
A1122_RS15555	COG3328	transposase activity
A1122_RS15730	COG3328	transposase activity
A1122_RS15830	COG0582	viral genome integration into host DNA
A1122_RS15840	COG0179	Fumarylacetoacetate (FAA) hydrolase
A1122_RS15860	COG2894	cell division
A1122_RS15865	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A1122_RS15870	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A1122_RS15875	COG0318	PFAM AMP-dependent synthetase and ligase
A1122_RS15890	COG1199	ATP-dependent helicase activity
A1122_RS15895	COG0251	oxidation-reduction process
A1122_RS15910	COG0800	Aldolase
A1122_RS15915	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A1122_RS15920	COG1737	Transcriptional regulator
A1122_RS15925	COG0469	pyruvate kinase activity
A1122_RS15930	COG1560	Kdo2-lipid A biosynthetic process
A1122_RS15935	COG0739	heme binding
A1122_RS15940	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
A1122_RS15950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A1122_RS15975	COG0494	nUDIX hydrolase
A1122_RS15985	COG1801	Protein of unknown function DUF72
A1122_RS15990	COG3788	relative of glutathione S-transferase, MAPEG superfamily
A1122_RS16010	COG3102	Protein conserved in bacteria
A1122_RS16030	COG0728	peptidoglycan biosynthetic process
A1122_RS16035	COG0673	inositol 2-dehydrogenase activity
A1122_RS16040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A1122_RS16055	COG3381	protein complex oligomerization
A1122_RS16070	COG1940	carbohydrate kinase activity
A1122_RS16075	COG0584	glycerophosphoryl diester phosphodiesterase
A1122_RS16080	COG3842	ATPase activity
A1122_RS16095	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1122_RS16100	COG3833	ABC-type maltose transport systems, permease component
A1122_RS16125	COG0659	secondary active sulfate transmembrane transporter activity
A1122_RS16140	COG0659	secondary active sulfate transmembrane transporter activity
A1122_RS16165	COG2890	protein-(glutamine-N5) methyltransferase activity
A1122_RS16195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A1122_RS16215	COG0012	GTP binding
A1122_RS16270	COG5002	protein histidine kinase activity
A1122_RS16310	COG0500	methyltransferase
A1122_RS16335	COG3328	transposase activity
A1122_RS16380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_RS16385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1122_RS16390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A1122_RS16405	COG0402	S-adenosylhomocysteine deaminase activity
A1122_RS16460	COG3842	ATPase activity
A1122_RS16465	COG0395	ABC-type sugar transport system, permease component
A1122_RS16470	COG1175	transmembrane transport
A1122_RS16480	COG0673	inositol 2-dehydrogenase activity
A1122_RS16490	COG2188	Transcriptional regulator
A1122_RS16635	COG2197	response regulator
A1122_RS16645	COG3136	membrane protein required for alginate biosynthesis
A1122_RS16665	COG1113	amino acid transport
A1122_RS16685	COG2822	iron ion transport
A1122_RS16690	COG0672	)-iron permease
A1122_RS16705	COG0506	proline dehydrogenase activity
A1122_RS16705	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A1122_RS16705	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A1122_RS16720	COG1126	abc transporter atp-binding protein
A1122_RS16725	COG0765	amino acid transport
A1122_RS16730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS16745	COG1191	sigma factor activity
A1122_RS16780	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A1122_RS16785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
A1122_RS16790	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A1122_RS16805	COG1677	Flagellar hook-basal body complex protein FliE
A1122_RS16825	COG1157	protein secretion by the type III secretion system
A1122_RS16840	COG1580	Controls the rotational direction of flagella during chemotaxis
A1122_RS16865	COG1987	bacterial-type flagellum assembly
A1122_RS16885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A1122_RS16890	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS16895	COG1129	ABC transporter
A1122_RS16905	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS16910	COG3347	Dehydrogenase
A1122_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS16915	COG2390	Transcriptional regulator
A1122_RS16925	COG1256	bacterial-type flagellum assembly
A1122_RS16965	COG1558	bacterial-type flagellum-dependent cell motility
A1122_RS16970	COG1815	bacterial-type flagellum-dependent cell motility
A1122_RS16980	COG2747	anti-sigma28 factor FlgM
A1122_RS16985	COG3418	PFAM FlgN family protein
A1122_RS17010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1122_RS17015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A1122_RS17045	COG2372	response to copper ion
A1122_RS17050	COG1528	Iron-storage protein
A1122_RS17065	COG1770	oligopeptidase
A1122_RS17080	COG3141	response to X-ray
A1122_RS17085	COG0513	Belongs to the DEAD box helicase family
A1122_RS17110	COG1760	l-serine dehydratase
A1122_RS17115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A1122_RS17120	COG2368	4-hydroxyphenylacetate
A1122_RS17135	COG3971	2-oxopent-4-enoate hydratase activity
A1122_RS17145	COG3384	dioxygenase
A1122_RS17150	COG1012	belongs to the aldehyde dehydrogenase family
A1122_RS17165	COG1846	Transcriptional regulator
A1122_RS17170	COG1253	flavin adenine dinucleotide binding
A1122_RS17175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A1122_RS17175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_RS17180	COG3715	PTS system
A1122_RS17185	COG3716	PTS system mannose fructose sorbose family IID component
A1122_RS17205	COG5002	protein histidine kinase activity
A1122_RS17205	COG5001	Diguanylate cyclase
A1122_RS17205	COG3447	MASE1 domain protein
A1122_RS17215	COG2226	methyltransferase
A1122_RS17220	COG1496	oxidoreductase activity
A1122_RS17245	COG1113	amino acid transport
A1122_RS17280	COG2207	Transcriptional regulator
A1122_RS17290	COG1132	(ABC) transporter
A1122_RS17335	COG3328	transposase activity
A1122_RS17340	COG1917	Cupin 2, conserved barrel domain protein
A1122_RS17350	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS17360	COG1175	transmembrane transport
A1122_RS17365	COG0395	ABC-type sugar transport system, permease component
A1122_RS17370	COG3842	ATPase activity
A1122_RS17375	COG1653	transport
A1122_RS17380	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A1122_RS17385	COG1988	membrane-bound metal-dependent
A1122_RS17390	COG1823	symporter activity
A1122_RS17395	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1122_RS17405	COG0823	Involved in the tonB-independent uptake of proteins
A1122_RS17410	COG2814	Major facilitator Superfamily
A1122_RS17415	COG3121	Chaperone
A1122_RS17430	COG3121	Chaperone
A1122_RS17435	COG3539	Fimbrial protein
A1122_RS17445	COG0793	Belongs to the peptidase S41A family
A1122_RS17455	COG1956	GAF domain-containing protein
A1122_RS17460	COG2995	paraquat-inducible protein a
A1122_RS17465	COG3008	intermembrane lipid transfer
A1122_RS17485	COG3121	Chaperone
A1122_RS17540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A1122_RS17550	COG5295	Hep Hag repeat protein
A1122_RS17560	COG3023	N-Acetylmuramoyl-L-alanine amidase
A1122_RS17570	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
A1122_RS17575	COG0745	RESPONSE REGULATOR receiver
A1122_RS17585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A1122_RS17590	COG0840	transmembrane signaling receptor activity
A1122_RS17595	COG0840	transmembrane signaling receptor activity
A1122_RS17600	COG0840	transmembrane signaling receptor activity
A1122_RS17620	COG2964	Protein conserved in bacteria
A1122_RS17630	COG0251	oxidation-reduction process
A1122_RS17635	COG2271	Major facilitator Superfamily
A1122_RS17640	COG0835	chemotaxis
A1122_RS17645	COG2198	Histidine kinase
A1122_RS17645	COG0643	Histidine kinase
A1122_RS17650	COG1360	Flagellar Motor Protein
A1122_RS17675	COG1285	pathogenesis
A1122_RS17705	COG0604	alcohol dehydrogenase
A1122_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS17705	COG3321	synthase
A1122_RS17715	COG1522	sequence-specific DNA binding
A1122_RS17740	COG1733	regulation of RNA biosynthetic process
A1122_RS17745	COG0702	epimerase
A1122_RS17750	COG0840	transmembrane signaling receptor activity
A1122_RS17765	COG0538	isocitrate dehydrogenase activity
A1122_RS17770	COG1187	pseudouridine synthase activity
A1122_RS17790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A1122_RS17800	COG0745	RESPONSE REGULATOR receiver
A1122_RS17810	COG2850	peptidyl-arginine hydroxylation
A1122_RS17825	COG1940	carbohydrate kinase activity
A1122_RS17830	COG4591	ABC-type transport system involved in lipoprotein release permease component
A1122_RS17840	COG4591	ABC-type transport system involved in lipoprotein release permease component
A1122_RS17845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A1122_RS17850	COG3134	Outer membrane lipoprotein
A1122_RS17865	COG3328	transposase activity
A1122_RS17880	COG1252	NADH dehydrogenase
A1122_RS17890	COG1472	Belongs to the glycosyl hydrolase 3 family
A1122_RS17905	COG5633	Lipoprotein
A1122_RS17910	COG0537	adenosine 5'-monophosphoramidase activity
A1122_RS17915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A1122_RS17925	COG1263	PTS System
A1122_RS17925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A1122_RS17930	COG0084	hydrolase, TatD family'
A1122_RS17935	COG0470	DNA polymerase III
A1122_RS17945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A1122_RS17950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A1122_RS17960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_RS17990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A1122_RS17995	COG1399	metal-binding, possibly nucleic acid-binding protein
A1122_RS18000	COG0424	maF-like protein
A1122_RS18015	COG0564	pseudouridine synthase activity
A1122_RS18020	COG1530	ribonuclease E activity
A1122_RS18025	COG3328	transposase activity
A1122_RS18030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A1122_RS18055	COG3328	transposase activity
A1122_RS18060	COG2223	nitrite transmembrane transporter activity
A1122_RS18080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A1122_RS18105	COG3122	Protein conserved in bacteria
A1122_RS18125	COG0534	Mate efflux family protein
A1122_RS18140	COG4948	Mandelate Racemase Muconate Lactonizing
A1122_RS18150	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS18155	COG3011	Protein conserved in bacteria
A1122_RS18160	COG2271	Major facilitator Superfamily
A1122_RS18165	COG1388	LysM domain
A1122_RS18165	COG1470	cell adhesion involved in biofilm formation
A1122_RS18170	COG3328	transposase activity
A1122_RS18185	COG2925	Exonuclease
A1122_RS18190	COG0531	amino acid
A1122_RS18200	COG0371	Dehydrogenase
A1122_RS18205	COG1129	ABC transporter
A1122_RS18210	COG1129	ABC transporter
A1122_RS18215	COG1172	Belongs to the binding-protein-dependent transport system permease family
A1122_RS18225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_RS18235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A1122_RS18245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A1122_RS18245	COG0131	Imidazoleglycerol-phosphate dehydratase
A1122_RS18265	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A1122_RS18265	COG0140	phosphoribosyl-ATP diphosphatase activity
A1122_RS18275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1122_RS18280	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A1122_RS18295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A1122_RS18300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_RS18305	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_RS18310	COG1120	ATPase activity
A1122_RS18325	COG3486	L-lysine 6-monooxygenase (NADPH) activity
A1122_RS18330	COG0076	glutamate decarboxylase activity
A1122_RS18335	COG4114	ferric iron reductase
A1122_RS18340	COG1253	flavin adenine dinucleotide binding
A1122_RS18345	COG2982	Protein involved in outer membrane biogenesis
A1122_RS18360	COG0489	protein tyrosine kinase activity
A1122_RS18405	COG2814	Major facilitator Superfamily
A1122_RS18415	COG1346	cytolysis
A1122_RS18430	COG2949	membrane
A1122_RS18435	COG4211	Belongs to the binding-protein-dependent transport system permease family
A1122_RS18450	COG2311	Membrane
A1122_RS18460	COG0477	Major facilitator Superfamily
A1122_RS18465	COG0583	DNA-binding transcription factor activity
A1122_RS18500	COG1136	(ABC) transporter
A1122_RS18510	COG0303	'Molybdopterin
A1122_RS18520	COG3328	transposase activity
A1122_RS18530	COG0488	(ABC) transporter
A1122_RS18665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A1122_RS18670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A1122_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS18685	COG1024	Enoyl-CoA hydratase
A1122_RS18695	COG3425	synthase
A1122_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS18705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_RS18710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A1122_RS18720	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS18755	COG2920	part of a sulfur-relay system
A1122_RS18775	COG1832	CoA-binding protein
A1122_RS18790	COG0210	DNA helicase
A1122_RS18795	COG3304	Inner membrane component domain
A1122_RS18800	COG1289	transmembrane transporter activity
A1122_RS18805	COG3070	regulator of competence-specific genes
A1122_RS18835	COG1067	ATP-dependent peptidase activity
A1122_RS18850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_RS18865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS18895	COG1120	ATPase activity
A1122_RS18920	COG4160	amino acid transport
A1122_RS18925	COG4215	(ABC) transporter
A1122_RS18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS18935	COG1126	abc transporter atp-binding protein
A1122_RS18940	COG1605	Chorismate mutase
A1122_RS18950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A1122_RS18955	COG0702	epimerase
A1122_RS18960	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
A1122_RS18965	COG0028	Belongs to the TPP enzyme family
A1122_RS18970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_RS18980	COG2431	L-lysine efflux transmembrane transporter activity
A1122_RS18985	COG3593	DNA synthesis involved in DNA repair
A1122_RS18990	COG2990	Protein conserved in bacteria
A1122_RS18995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_RS19005	COG1278	Cold shock
A1122_RS19015	COG0542	response to heat
A1122_RS19025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A1122_RS19035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A1122_RS19050	COG0492	ferredoxin-NADP+ reductase activity
A1122_RS19060	COG3107	peptidoglycan biosynthetic process
A1122_RS19060	COG1674	ftsk spoiiie
A1122_RS19070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A1122_RS19085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A1122_RS19095	COG1882	Formate acetyltransferase
A1122_RS19100	COG2116	formate transmembrane transporter activity
A1122_RS19105	COG1944	ATP diphosphatase activity
A1122_RS19110	COG0252	asparaginase activity
A1122_RS19115	COG5295	Hep Hag repeat protein
A1122_RS19115	COG5295	Hep Hag repeat protein
A1122_RS19140	COG0539	negative regulation of cytoplasmic translation
A1122_RS19150	COG0658	competence protein
A1122_RS19150	COG2333	competence protein COMEC
A1122_RS19165	COG5383	Protein conserved in bacteria
A1122_RS19175	COG1278	Cold shock
A1122_RS19190	COG3173	Aminoglycoside phosphotransferase
A1122_RS19200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A1122_RS19230	COG2989	Protein conserved in bacteria
A1122_RS19235	COG3108	Peptidase M15
A1122_RS19240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1122_RS19245	COG1448	Aminotransferase
A1122_RS19265	COG0308	aminopeptidase N
A1122_RS19280	COG3217	Mosc domain protein beta barrel domain protein
A1122_RS19280	COG0633	Ferredoxin
A1122_RS19290	COG0488	(ABC) transporter
A1122_RS19295	COG2995	paraquat-inducible protein a
A1122_RS19300	COG3008	intermembrane lipid transfer
A1122_RS19300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A1122_RS19305	COG3009	Protein conserved in bacteria
A1122_RS19315	COG3130	regulation of translation
A1122_RS19330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A1122_RS19350	COG3657	addiction module killer protein
A1122_RS19410	COG0582	viral genome integration into host DNA
A1122_RS19430	COG2867	negative regulation of translational initiation
A1122_RS19440	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A1122_RS19445	COG0497	DNA recombination
A1122_RS19450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A1122_RS19465	COG2009	succinate dehydrogenase
A1122_RS19470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A1122_RS19475	COG1053	succinate dehydrogenase
A1122_RS19485	COG0567	Dehydrogenase, E1 component
A1122_RS19490	COG0508	dehydrogenase complex catalyzes the overall conversion of
A1122_RS19500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A1122_RS19505	COG1271	oxidase subunit
A1122_RS19510	COG1294	oxidase, subunit
A1122_RS19515	COG4890	Cyd operon protein YbgT
A1122_RS19520	COG3790	cyd operon protein YbgE
A1122_RS19525	COG0824	Thioesterase
A1122_RS19530	COG0811	peptide transport
A1122_RS19535	COG0848	biopolymer transport protein
A1122_RS19540	COG3064	Membrane
A1122_RS19540	COG3064	Membrane
A1122_RS19550	COG2885	chlorophyll binding
A1122_RS19555	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
A1122_RS19585	COG1230	cation diffusion facilitator family transporter
A1122_RS19590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1122_RS19605	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A1122_RS19620	COG2017	converts alpha-aldose to the beta-anomer
A1122_RS19635	COG1085	galactose-1-phosphate uridylyltransferase
A1122_RS19640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A1122_RS19655	COG1119	ATPase activity
A1122_RS19660	COG3585	molybdate ion transport
A1122_RS19660	COG2005	Transcriptional regulator
A1122_RS19670	COG0725	ABC transporter, periplasmic molybdate-binding protein
A1122_RS19675	COG4149	molybdate abc transporter
A1122_RS19685	COG0561	phosphatase activity
A1122_RS19710	COG2226	methyltransferase
A1122_RS19720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A1122_RS19730	COG4628	conserved protein (DUF2132)
A1122_RS19735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A1122_RS19745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A1122_RS19755	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
A1122_RS19760	COG0314	molybdopterin synthase activity
A1122_RS19765	COG0670	Belongs to the BI1 family
A1122_RS19795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A1122_RS19800	COG0583	DNA-binding transcription factor activity
A1122_RS19810	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A1122_RS19815	COG2211	Major facilitator Superfamily
A1122_RS19830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A1122_RS19840	COG1686	Belongs to the peptidase S11 family
A1122_RS19845	COG0277	FAD linked oxidase domain protein
A1122_RS19865	COG2261	transglycosylase associated protein
A1122_RS19875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
A1122_RS19890	COG4807	Protein conserved in bacteria
A1122_RS19910	COG1122	ATPase activity
A1122_RS19930	COG2897	thiosulfate sulfurtransferase activity
A1122_RS19935	COG1732	Glycine betaine
A1122_RS19940	COG1732	Glycine betaine
A1122_RS19945	COG1174	glycine betaine transport
A1122_RS19950	COG1125	glycine betaine transport
A1122_RS19955	COG1174	glycine betaine transport
A1122_RS19960	COG0531	amino acid
A1122_RS19965	COG1982	Orn Lys Arg decarboxylase major
A1122_RS19975	COG0697	spore germination
A1122_RS20000	COG0814	amino acid
A1122_RS20015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A1122_RS20045	COG2205	protein histidine kinase activity
A1122_RS20045	COG0784	Response regulator, receiver
A1122_RS20055	COG2198	Histidine kinase
A1122_RS20055	COG0642	Histidine kinase
A1122_RS20060	COG2198	Histidine kinase
A1122_RS20060	COG0642	Histidine kinase
A1122_RS20065	COG2223	nitrite transmembrane transporter activity
A1122_RS20095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A1122_RS20140	COG3395	kinase activity
A1122_RS20150	COG1349	DNA-binding transcription factor activity
A1122_RS20155	COG3622	Belongs to the hyi family
A1122_RS20175	COG4386	tail sheath protein
A1122_RS20215	COG3299	homolog of phage Mu protein gp47
A1122_RS20235	COG1737	Transcriptional regulator
A1122_RS20240	COG2723	6-phospho-beta-galactosidase activity
A1122_RS20260	COG3157	Type VI secretion system effector, Hcp
A1122_RS20275	COG3083	sulfuric ester hydrolase activity
A1122_RS20280	COG3082	Protein of unknown function (DUF1414)
A1122_RS20300	COG1061	Type III restriction enzyme res subunit
A1122_RS20305	COG1187	pseudouridine synthase activity
A1122_RS20310	COG2814	Major facilitator Superfamily
A1122_RS20320	COG4172	Belongs to the ABC transporter superfamily
A1122_RS20325	COG4239	(ABC) transporter, permease
A1122_RS20330	COG4174	ABC transporter (Permease)
A1122_RS20335	COG4166	transmembrane transport
A1122_RS20340	COG2200	EAL domain
A1122_RS20345	COG0791	NLP P60 protein
A1122_RS20350	COG0671	phosphoesterase, PA-phosphatase related
A1122_RS20355	COG0523	cobalamin synthesis protein
A1122_RS20365	COG2186	Transcriptional regulator
A1122_RS20370	COG0246	Mannitol dehydrogenase
A1122_RS20395	COG1028	Short-chain dehydrogenase reductase Sdr
A1122_RS20430	COG1129	ABC transporter
A1122_RS20440	COG0494	nUDIX hydrolase
A1122_RS20450	COG1105	Belongs to the carbohydrate kinase PfkB family
A1122_RS20455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_RS20455	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A1122_RS20455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A1122_RS20460	COG3710	Transcriptional regulator
A1122_RS20475	COG3121	Chaperone
A1122_RS20480	COG3188	usher protein
A1122_RS20490	COG2855	membrane
A1122_RS20495	COG0583	DNA-binding transcription factor activity
A1122_RS20500	COG0833	amino acid
A1122_RS20510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A1122_RS20520	COG4771	TonB-dependent receptor
A1122_RS20525	COG0625	glutathione transferase activity
A1122_RS20550	COG2011	ABC-type metal ion transport system permease component
A1122_RS20555	COG1686	Belongs to the peptidase S11 family
A1122_RS20565	COG0814	amino acid
A1122_RS20570	COG1349	DNA-binding transcription factor activity
A1122_RS20580	COG0671	phosphoesterase, PA-phosphatase related
A1122_RS20615	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A1122_RS20620	COG3842	ATPase activity
A1122_RS20625	COG1176	ABC-type spermidine putrescine transport system, permease component I
A1122_RS20630	COG1177	transmembrane transport
A1122_RS20645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A1122_RS20670	COG1953	Uracil, thiamine, allantoin
A1122_RS20690	COG2226	methyltransferase
A1122_RS20695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A1122_RS20700	COG0741	lytic transglycosylase activity
A1122_RS20700	COG1388	LysM domain
A1122_RS20715	COG0656	L-ascorbic acid biosynthetic process
A1122_RS20750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A1122_RS20760	COG2011	ABC-type metal ion transport system permease component
A1122_RS20765	COG1464	Belongs to the NlpA lipoprotein family
A1122_RS20775	COG1720	tRNA m6t6A37 methyltransferase activity
A1122_RS20785	COG3015	lipoprotein NlpE involved in copper resistance
A1122_RS20795	COG4681	YaeQ
A1122_RS20805	COG4568	rho-dependent transcription termination
A1122_RS20815	COG0037	tRNA processing
A1122_RS20820	COG0346	lactoylglutathione lyase activity
A1122_RS20830	COG0587	DNA-directed DNA polymerase activity
A1122_RS20855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A1122_RS20870	COG0750	zinc metalloprotease
A1122_RS20875	COG0575	Belongs to the CDS family
A1122_RS20935	COG0564	pseudouridine synthase activity
A1122_RS20940	COG3098	single-species biofilm formation
A1122_RS20960	COG1611	Belongs to the LOG family
A1122_RS20975	COG2363	Small membrane protein
A1122_RS20980	COG0583	DNA-binding transcription factor activity
A1122_RS20985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A1122_RS20990	COG2166	iron-sulfur cluster assembly
A1122_RS20995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A1122_RS21000	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A1122_RS21015	COG0860	N-Acetylmuramoyl-L-alanine amidase
A1122_RS21025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A1122_RS21030	COG1074	ATP-dependent DNA helicase activity
A1122_RS21040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A1122_RS21075	COG4771	TonB-dependent receptor
A1122_RS21080	COG2195	Cleaves the N-terminal amino acid of tripeptides
A1122_RS21085	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A1122_RS21125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A1122_RS21135	COG5001	Diguanylate cyclase
A1122_RS21140	COG2801	Transposase and inactivated derivatives
A1122_RS21150	COG2211	Major facilitator Superfamily
A1122_RS21475	COG1172	Belongs to the binding-protein-dependent transport system permease family