locus-tag	class	description
CH57_RS00040	COG0402	S-adenosylhomocysteine deaminase activity
CH57_RS00060	COG3842	ATPase activity
CH57_RS00115	COG0402	S-adenosylhomocysteine deaminase activity
CH57_RS00130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH57_RS00135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH57_RS00140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_RS00185	COG3328	transposase activity
CH57_RS00210	COG0500	methyltransferase
CH57_RS00250	COG5002	protein histidine kinase activity
CH57_RS00305	COG0012	GTP binding
CH57_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH57_RS00355	COG2890	protein-(glutamine-N5) methyltransferase activity
CH57_RS00380	COG0659	secondary active sulfate transmembrane transporter activity
CH57_RS00395	COG0659	secondary active sulfate transmembrane transporter activity
CH57_RS00420	COG3833	ABC-type maltose transport systems, permease component
CH57_RS00425	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH57_RS00440	COG3842	ATPase activity
CH57_RS00445	COG0584	glycerophosphoryl diester phosphodiesterase
CH57_RS00450	COG1940	carbohydrate kinase activity
CH57_RS00465	COG3381	protein complex oligomerization
CH57_RS00480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH57_RS00485	COG0673	inositol 2-dehydrogenase activity
CH57_RS00490	COG0728	peptidoglycan biosynthetic process
CH57_RS00510	COG3102	Protein conserved in bacteria
CH57_RS00530	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH57_RS00535	COG1801	Protein of unknown function DUF72
CH57_RS00545	COG0494	nUDIX hydrolase
CH57_RS00570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH57_RS00580	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH57_RS00585	COG0739	heme binding
CH57_RS00590	COG1560	Kdo2-lipid A biosynthetic process
CH57_RS00595	COG0469	pyruvate kinase activity
CH57_RS00600	COG1737	Transcriptional regulator
CH57_RS00605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH57_RS00610	COG0800	Aldolase
CH57_RS00625	COG0251	oxidation-reduction process
CH57_RS00630	COG1199	ATP-dependent helicase activity
CH57_RS00645	COG0318	PFAM AMP-dependent synthetase and ligase
CH57_RS00650	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH57_RS00655	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH57_RS00660	COG2894	cell division
CH57_RS00675	COG2951	lytic endotransglycosylase activity
CH57_RS00680	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH57_RS00690	COG0582	viral genome integration into host DNA
CH57_RS00790	COG3328	transposase activity
CH57_RS00965	COG3328	transposase activity
CH57_RS00975	COG1104	cysteine desulfurase activity
CH57_RS01005	COG2719	SpoVR family
CH57_RS01015	COG2814	Major facilitator Superfamily
CH57_RS01025	COG0583	DNA-binding transcription factor activity
CH57_RS01040	COG2766	serine protein kinase
CH57_RS01045	COG3713	MltA-interacting MipA family protein
CH57_RS01065	COG3139	Protein of unknown function (DUF1315)
CH57_RS01070	COG1335	isochorismatase
CH57_RS01075	COG0252	asparaginase activity
CH57_RS01080	COG0616	signal peptide processing
CH57_RS01085	COG0778	Nitroreductase
CH57_RS01090	COG0709	Synthesizes selenophosphate from selenide and ATP
CH57_RS01095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH57_RS01105	COG0494	nUDIX hydrolase
CH57_RS01110	COG0708	Exodeoxyribonuclease III
CH57_RS01115	COG0583	DNA-binding transcription factor activity
CH57_RS01125	COG3328	transposase activity
CH57_RS01130	COG0788	formyltetrahydrofolate deformylase activity
CH57_RS01140	COG0745	RESPONSE REGULATOR receiver
CH57_RS01150	COG2916	Histone family protein nucleoid-structuring protein H-NS
CH57_RS01170	COG1454	alcohol dehydrogenase
CH57_RS01170	COG1012	belongs to the aldehyde dehydrogenase family
CH57_RS01175	COG2095	MarC family integral membrane protein
CH57_RS01185	COG0601	transmembrane transport
CH57_RS01190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_RS01195	COG0444	Belongs to the ABC transporter superfamily
CH57_RS01200	COG4608	Belongs to the ABC transporter superfamily
CH57_RS01240	COG2350	Protein conserved in bacteria
CH57_RS01245	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH57_RS01285	COG3047	cAMP biosynthetic process
CH57_RS01305	COG0134	indole-3-glycerol-phosphate synthase activity
CH57_RS01305	COG0135	phosphoribosylanthranilate isomerase activity
CH57_RS01315	COG0512	Glutamine amidotransferase of anthranilate synthase
CH57_RS01340	COG0009	L-threonylcarbamoyladenylate synthase
CH57_RS01345	COG1187	pseudouridine synthase activity
CH57_RS01355	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS01360	COG0616	signal peptide processing
CH57_RS01380	COG0583	DNA-binding transcription factor activity
CH57_RS01390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH57_RS01400	COG0671	phosphoesterase, PA-phosphatase related
CH57_RS01405	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH57_RS01410	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH57_RS01425	COG0023	Translation Initiation Factor
CH57_RS01445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH57_RS01450	COG2879	small protein
CH57_RS01455	COG1966	Carbon starvation protein
CH57_RS01465	COG2271	Major facilitator Superfamily
CH57_RS01470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_RS01475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH57_RS01485	COG4659	FMN binding
CH57_RS01490	COG4658	electron transport chain
CH57_RS01495	COG2207	Transcriptional regulator
CH57_RS01495	COG3708	Transcriptional regulator
CH57_RS01525	COG1132	(ABC) transporter
CH57_RS01535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_RS01540	COG2274	protein secretion by the type I secretion system
CH57_RS01555	COG1879	ABC-type sugar transport system periplasmic component
CH57_RS01560	COG1129	ABC transporter
CH57_RS01565	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS01575	COG0673	inositol 2-dehydrogenase activity
CH57_RS01580	COG0385	Bile acid
CH57_RS01590	COG5339	Protein conserved in bacteria
CH57_RS01600	COG0114	fumarate hydratase activity
CH57_RS01620	COG1940	carbohydrate kinase activity
CH57_RS01625	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH57_RS01630	COG0038	chloride channel
CH57_RS01680	COG4128	Pfam Zonular occludens toxin
CH57_RS01740	COG4128	Pfam Zonular occludens toxin
CH57_RS01760	COG1609	Transcriptional regulator
CH57_RS01780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH57_RS01785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH57_RS01810	COG0028	Belongs to the TPP enzyme family
CH57_RS01815	COG0440	acetolactate synthase activity
CH57_RS01820	COG1011	Hydrolase
CH57_RS01840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH57_RS01845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH57_RS01850	COG0589	response to stress
CH57_RS01870	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH57_RS01875	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH57_RS01890	COG0531	amino acid
CH57_RS01900	COG0745	RESPONSE REGULATOR receiver
CH57_RS01905	COG2205	protein histidine kinase activity
CH57_RS01910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH57_RS01945	COG3038	cytochrome b561
CH57_RS01960	COG3591	Belongs to the peptidase S1B family
CH57_RS01975	COG1643	Atp-dependent helicase
CH57_RS01985	COG2390	Transcriptional regulator
CH57_RS01990	COG0246	Mannitol dehydrogenase
CH57_RS01995	COG3784	Protein of unknown function (DUF1318)
CH57_RS02005	COG2911	Protein conserved in bacteria
CH57_RS02010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH57_RS02015	COG3187	Heat shock protein
CH57_RS02020	COG3042	response to heat
CH57_RS02025	COG1285	pathogenesis
CH57_RS02035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH57_RS02035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH57_RS02035	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH57_RS02035	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH57_RS02045	COG0657	acetylesterase activity
CH57_RS02060	COG4166	transmembrane transport
CH57_RS02065	COG2866	Carboxypeptidase
CH57_RS02070	COG4948	Mandelate Racemase Muconate Lactonizing
CH57_RS02075	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH57_RS02090	COG5642	Protein of unknown function (DUF2384)
CH57_RS02095	COG5654	RES domain protein
CH57_RS02105	COG3106	COG3106 Predicted ATPase
CH57_RS02115	COG1983	PspC domain protein
CH57_RS02125	COG1842	Phage shock protein A
CH57_RS02130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH57_RS02150	COG4166	transmembrane transport
CH57_RS02155	COG4168	peptide transport system, permease
CH57_RS02160	COG4171	peptide transport system, permease
CH57_RS02170	COG4172	Belongs to the ABC transporter superfamily
CH57_RS02175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH57_RS02175	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH57_RS02180	COG3104	oligopeptide transport
CH57_RS02205	COG0625	glutathione transferase activity
CH57_RS02225	COG3895	Periplasmic Protein
CH57_RS02235	COG3133	Outer membrane lipoprotein
CH57_RS02245	COG4989	oxidoreductase activity
CH57_RS02250	COG3313	Fe-S protein
CH57_RS02255	COG2194	sulfuric ester hydrolase activity
CH57_RS02260	COG1309	transcriptional regulator
CH57_RS02265	COG1902	pentaerythritol trinitrate reductase activity
CH57_RS02275	COG0346	lactoylglutathione lyase activity
CH57_RS02280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH57_RS02285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH57_RS02295	COG0791	NLP P60 protein
CH57_RS02310	COG0583	DNA-binding transcription factor activity
CH57_RS02315	COG2814	Major facilitator Superfamily
CH57_RS02320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH57_RS02325	COG0307	riboflavin synthase, alpha
CH57_RS02375	COG1376	ErfK ybiS ycfS ynhG family protein
CH57_RS02375	COG1388	LysM domain
CH57_RS02390	COG0719	Fe-S assembly protein
CH57_RS02395	COG0396	ATPase activity
CH57_RS02400	COG0719	Fe-S assembly protein
CH57_RS02405	COG0316	Belongs to the HesB IscA family
CH57_RS02415	COG2050	protein possibly involved in aromatic compounds catabolism
CH57_RS02420	COG0247	lactate metabolic process
CH57_RS02420	COG0277	FAD linked oxidase domain protein
CH57_RS02425	COG0628	permease
CH57_RS02430	COG0574	Belongs to the PEP-utilizing enzyme family
CH57_RS02430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH57_RS02455	COG0791	NLP P60 protein
CH57_RS02500	COG0386	Belongs to the glutathione peroxidase family
CH57_RS02515	COG0776	regulation of translation
CH57_RS02520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH57_RS02520	COG0072	phenylalanine-tRNA ligase activity
CH57_RS02550	COG4249	Peptidase C14 caspase catalytic subunit p20
CH57_RS02575	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH57_RS02580	COG1121	(ABC) transporter
CH57_RS02585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH57_RS02590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH57_RS02600	COG3001	Fructosamine kinase
CH57_RS02610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_RS02615	COG3328	transposase activity
CH57_RS02630	COG0628	permease
CH57_RS02660	COG3916	Acyl-homoserine-lactone synthase
CH57_RS02665	COG2771	luxR family
CH57_RS02670	COG0583	DNA-binding transcription factor activity
CH57_RS02680	COG0477	Major facilitator Superfamily
CH57_RS02690	COG0667	Aldo Keto reductase
CH57_RS02720	COG1203	CRISPR-associated helicase, Cas3
CH57_RS02725	COG1518	maintenance of DNA repeat elements
CH57_RS02730	COG0668	transmembrane transport
CH57_RS02750	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH57_RS02755	COG0395	ABC-type sugar transport system, permease component
CH57_RS02770	COG1609	Transcriptional regulator
CH57_RS02780	COG3842	ATPase activity
CH57_RS02790	COG3210	domain, Protein
CH57_RS02810	COG3210	domain, Protein
CH57_RS02830	COG3210	domain, Protein
CH57_RS02835	COG2831	hemolysin activation secretion protein
CH57_RS02840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_RS02845	COG4638	Rieske (2fe-2S)
CH57_RS02850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH57_RS02860	COG0473	3-isopropylmalate dehydrogenase activity
CH57_RS02865	COG0583	DNA-binding transcription factor activity
CH57_RS02870	COG1609	Transcriptional regulator
CH57_RS02875	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS02880	COG1129	ABC transporter
CH57_RS02885	COG1879	ABC-type sugar transport system periplasmic component
CH57_RS02890	COG1063	alcohol dehydrogenase
CH57_RS02910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH57_RS02940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS02945	COG0765	amino acid transport
CH57_RS02950	COG1126	abc transporter atp-binding protein
CH57_RS02980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH57_RS02995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH57_RS03010	COG1169	isochorismate synthase
CH57_RS03020	COG4575	ribosome binding
CH57_RS03035	COG0129	dihydroxy-acid dehydratase activity
CH57_RS03050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH57_RS03060	COG1609	Transcriptional regulator
CH57_RS03065	COG1649	PFAM Uncharacterised BCR, COG1649
CH57_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS03075	COG3265	gluconokinase activity
CH57_RS03080	COG2731	YhcH YjgK YiaL family protein
CH57_RS03095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH57_RS03100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH57_RS03110	COG0839	Belongs to the complex I subunit 6 family
CH57_RS03125	COG1034	ATP synthesis coupled electron transport
CH57_RS03145	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH57_RS03155	COG0583	DNA-binding transcription factor activity
CH57_RS03165	COG0436	Aminotransferase
CH57_RS03180	COG0471	metal ion transport
CH57_RS03180	COG0490	domain, Protein
CH57_RS03185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_RS03210	COG0857	belongs to the CobB CobQ family
CH57_RS03210	COG0280	phosphate acetyltransferase
CH57_RS03215	COG1609	Transcriptional regulator
CH57_RS03235	COG4953	penicillin-binding protein 1C
CH57_RS03240	COG2373	Large extracellular alpha-helical protein
CH57_RS03260	COG3962	Belongs to the TPP enzyme family
CH57_RS03275	COG1129	ABC transporter
CH57_RS03280	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS03285	COG0673	inositol 2-dehydrogenase activity
CH57_RS03290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_RS03300	COG3718	enzyme involved in inositol metabolism
CH57_RS03310	COG5265	(ABC) transporter
CH57_RS03335	COG2197	response regulator
CH57_RS03350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH57_RS03360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH57_RS03380	COG1686	Belongs to the peptidase S11 family
CH57_RS03385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH57_RS03390	COG0772	Belongs to the SEDS family
CH57_RS03395	COG0768	penicillin binding
CH57_RS03405	COG0799	negative regulation of ribosome biogenesis
CH57_RS03415	COG1466	dna polymerase III delta subunit
CH57_RS03430	COG2888	peptidyl-tyrosine sulfation
CH57_RS03435	COG1126	abc transporter atp-binding protein
CH57_RS03440	COG0765	amino acid transport
CH57_RS03445	COG0765	amino acid transport
CH57_RS03455	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH57_RS03460	COG4535	Mg2 and Co2 transporter CorC
CH57_RS03470	COG1702	phosphate starvation-inducible protein PhoH
CH57_RS03475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH57_RS03480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH57_RS03515	COG0367	asparagine synthase
CH57_RS03520	COG0647	UMP catabolic process
CH57_RS03525	COG1846	Transcriptional regulator
CH57_RS03525	COG1940	carbohydrate kinase activity
CH57_RS03530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH57_RS03540	COG1263	PTS System
CH57_RS03540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_RS03540	COG2190	(PTS) system
CH57_RS03565	COG0735	belongs to the Fur family
CH57_RS03585	COG0596	Alpha beta hydrolase
CH57_RS03595	COG0582	viral genome integration into host DNA
CH57_RS03600	COG2963	transposase activity
CH57_RS03605	COG0582	viral genome integration into host DNA
CH57_RS03625	COG2113	Glycine betaine
CH57_RS03630	COG4176	ABC-type proline glycine betaine transport system permease component
CH57_RS03635	COG4175	Glycine betaine
CH57_RS03640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH57_RS03675	COG3328	transposase activity
CH57_RS03685	COG1278	Cold shock
CH57_RS03690	COG0747	negative chemotaxis
CH57_RS03700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_RS03705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH57_RS03710	COG1124	(ABC) transporter
CH57_RS03715	COG0831	urea catabolic process
CH57_RS03740	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH57_RS03750	COG4413	Urea transporter
CH57_RS03755	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH57_RS03770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH57_RS03780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH57_RS03790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH57_RS03795	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH57_RS03800	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH57_RS03805	COG1917	Cupin 2, conserved barrel domain protein
CH57_RS03805	COG2169	Transcriptional regulator
CH57_RS03825	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH57_RS03830	COG0033	Phosphoglucomutase
CH57_RS03850	COG0745	RESPONSE REGULATOR receiver
CH57_RS03855	COG2205	protein histidine kinase activity
CH57_RS03890	COG3272	Protein of unknown function (DUF1722)
CH57_RS03900	COG5212	phosphodiesterase
CH57_RS03905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH57_RS03915	COG1984	allophanate hydrolase subunit 2
CH57_RS03965	COG0513	Belongs to the DEAD box helicase family
CH57_RS03975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH57_RS03990	COG3026	antisigma factor binding
CH57_RS03995	COG3086	response to oxidative stress
CH57_RS04080	COG2824	Alkylphosphonate utilization operon protein PhnA
CH57_RS04090	COG1704	LemA family
CH57_RS04110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH57_RS04115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH57_RS04120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH57_RS04130	COG1138	Cytochrome C-type biogenesis protein
CH57_RS04135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH57_RS04140	COG4235	cytochrome complex assembly
CH57_RS04140	COG3088	subunit of a heme lyase
CH57_RS04145	COG4235	cytochrome complex assembly
CH57_RS04145	COG3088	subunit of a heme lyase
CH57_RS04160	COG3691	Protein conserved in bacteria
CH57_RS04175	COG2062	phosphohistidine phosphatase, SixA
CH57_RS04185	COG2890	protein-(glutamine-N5) methyltransferase activity
CH57_RS04195	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CH57_RS04200	COG0730	response to heat
CH57_RS04205	COG3101	peptidyl-lysine hydroxylation
CH57_RS04220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_RS04225	COG1794	racemase activity, acting on amino acids and derivatives
CH57_RS04240	COG0697	spore germination
CH57_RS04265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH57_RS04275	COG0586	Pfam SNARE associated Golgi protein
CH57_RS04285	COG0285	dihydrofolate synthase activity
CH57_RS04290	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH57_RS04295	COG1286	toxin biosynthetic process
CH57_RS04300	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH57_RS04310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS04315	COG4215	(ABC) transporter
CH57_RS04320	COG4160	amino acid transport
CH57_RS04325	COG4598	ABC transporter
CH57_RS04330	COG1090	epimerase
CH57_RS04340	COG0622	Phosphoesterase
CH57_RS04345	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH57_RS04350	COG3037	sugar-specific permease SgaT UlaA
CH57_RS04355	COG3328	transposase activity
CH57_RS04360	COG4953	penicillin-binding protein 1C
CH57_RS04365	COG3423	Transcriptional regulator
CH57_RS04415	COG2850	peptidyl-arginine hydroxylation
CH57_RS04420	COG3328	transposase activity
CH57_RS04435	COG1472	Belongs to the glycosyl hydrolase 3 family
CH57_RS04455	COG0656	L-ascorbic acid biosynthetic process
CH57_RS04460	COG0667	Aldo Keto reductase
CH57_RS04490	COG2453	phosphatase
CH57_RS04490	COG0671	phosphoesterase, PA-phosphatase related
CH57_RS04495	COG2267	carboxylic ester hydrolase activity
CH57_RS04505	COG4589	Belongs to the CDS family
CH57_RS04510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH57_RS04560	COG2501	S4 domain
CH57_RS04580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH57_RS04585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH57_RS04605	COG0581	inorganic phosphate transmembrane transporter activity
CH57_RS04615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH57_RS04630	COG2239	Acts as a magnesium transporter
CH57_RS04635	COG0443	Heat shock 70 kDa protein
CH57_RS04640	COG1177	transmembrane transport
CH57_RS04645	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH57_RS04655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH57_RS04665	COG3842	ATPase activity
CH57_RS04690	COG2205	protein histidine kinase activity
CH57_RS04695	COG2205	protein histidine kinase activity
CH57_RS04700	COG0745	RESPONSE REGULATOR receiver
CH57_RS04705	COG3422	double-strand break repair
CH57_RS04710	COG0826	peptidase U32
CH57_RS04730	COG0351	phosphomethylpyrimidine kinase
CH57_RS04745	COG3328	transposase activity
CH57_RS04800	COG0516	GMP reductase activity
CH57_RS04800	COG0517	IMP dehydrogenase activity
CH57_RS04810	COG1645	bacterial-type flagellum-dependent swarming motility
CH57_RS04835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH57_RS04840	COG2976	Protein conserved in bacteria
CH57_RS04885	COG3468	outer membrane autotransporter barrel domain protein
CH57_RS04890	COG3468	outer membrane autotransporter barrel domain protein
CH57_RS04910	COG2975	iron-sulfur cluster assembly
CH57_RS04915	COG0633	Ferredoxin
CH57_RS04920	COG0443	Heat shock 70 kDa protein
CH57_RS04935	COG0822	iron-sulfur transferase activity
CH57_RS04940	COG1104	cysteine desulfurase activity
CH57_RS04965	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH57_RS04970	COG3683	transport system, periplasmic component
CH57_RS04975	COG3711	transcriptional antiterminator
CH57_RS04980	COG2814	Major facilitator Superfamily
CH57_RS05000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_RS05000	COG1017	nitric oxide dioxygenase activity
CH57_RS05005	COG2188	Transcriptional regulator
CH57_RS05010	COG2188	Transcriptional regulator
CH57_RS05015	COG0347	Belongs to the P(II) protein family
CH57_RS05020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH57_RS05020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH57_RS05025	COG2204	response regulator
CH57_RS05030	COG3170	Tfp pilus assembly protein FimV
CH57_RS05035	COG2205	protein histidine kinase activity
CH57_RS05075	COG0560	Phosphoserine phosphatase
CH57_RS05085	COG1737	Transcriptional regulator
CH57_RS05090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_RS05110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH57_RS05165	COG3188	usher protein
CH57_RS05170	COG3328	transposase activity
CH57_RS05175	COG3188	usher protein
CH57_RS05180	COG3121	Chaperone
CH57_RS05240	COG2951	lytic endotransglycosylase activity
CH57_RS05275	COG0243	molybdopterin cofactor binding
CH57_RS05280	COG0437	4 iron, 4 sulfur cluster binding
CH57_RS05285	COG3302	dmso reductase anchor subunit
CH57_RS05290	COG3381	protein complex oligomerization
CH57_RS05320	COG3038	cytochrome b561
CH57_RS05325	COG0436	Aminotransferase
CH57_RS05350	COG0667	Aldo Keto reductase
CH57_RS05365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH57_RS05420	COG3530	Putative quorum-sensing-regulated virulence factor
CH57_RS05435	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH57_RS05445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS05470	COG2205	protein histidine kinase activity
CH57_RS05475	COG0745	RESPONSE REGULATOR receiver
CH57_RS05480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_RS05495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH57_RS05515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH57_RS05525	COG5002	protein histidine kinase activity
CH57_RS05525	COG3850	Histidine kinase
CH57_RS05530	COG0745	RESPONSE REGULATOR receiver
CH57_RS05545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH57_RS05550	COG4208	sulfate ABC transporter
CH57_RS05555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH57_RS05560	COG4150	thiosulfate binding
CH57_RS05570	COG1737	Transcriptional regulator
CH57_RS05580	COG2731	YhcH YjgK YiaL family protein
CH57_RS05590	COG4886	Leucine-rich repeat (LRR) protein
CH57_RS05600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH57_RS05605	COG2837	iron assimilation
CH57_RS05615	COG3111	PFAM Bacterial OB fold (BOF) protein
CH57_RS05660	COG3005	denitrification pathway
CH57_RS05665	COG3043	anaerobic respiration
CH57_RS05675	COG3062	negative regulation of establishment of protein localization
CH57_RS05680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_RS05680	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_RS05685	COG2197	response regulator
CH57_RS05695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_RS05705	COG1988	membrane-bound metal-dependent
CH57_RS05710	COG0641	radical SAM
CH57_RS05715	COG3119	arylsulfatase activity
CH57_RS05720	COG3842	ATPase activity
CH57_RS05725	COG1175	transmembrane transport
CH57_RS05740	COG1393	Belongs to the ArsC family
CH57_RS05750	COG1876	peptidase activity
CH57_RS05770	COG2321	neutral zinc metallopeptidase
CH57_RS05790	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH57_RS05800	COG2716	regulation of RNA biosynthetic process
CH57_RS05805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH57_RS05825	COG0628	permease
CH57_RS05830	COG4783	chaperone-mediated protein folding
CH57_RS05835	COG1393	Belongs to the ArsC family
CH57_RS05860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH57_RS05870	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH57_RS05875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH57_RS05880	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH57_RS05885	COG4181	ATPase activity
CH57_RS05890	COG2755	lipolytic protein G-D-S-L family
CH57_RS05895	COG0300	oxidoreductase activity
CH57_RS05900	COG3118	belongs to the thioredoxin family
CH57_RS05905	COG0330	HflC and HflK could
CH57_RS05910	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH57_RS05915	COG0789	Transcriptional regulator
CH57_RS05920	COG2217	Heavy metal translocating P-type atpase
CH57_RS05925	COG3735	TraB family
CH57_RS05930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH57_RS05945	COG0737	Belongs to the 5'-nucleotidase family
CH57_RS05950	COG0737	Belongs to the 5'-nucleotidase family
CH57_RS05955	COG0737	Belongs to the 5'-nucleotidase family
CH57_RS05960	COG2223	nitrite transmembrane transporter activity
CH57_RS05965	COG4651	solute:proton antiporter activity
CH57_RS05965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH57_RS05970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_RS05975	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH57_RS06035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_RS06060	COG0543	2 iron, 2 sulfur cluster binding
CH57_RS06060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_RS06090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH57_RS06110	COG2832	Protein of unknown function (DUF454)
CH57_RS06125	COG3264	Mechanosensitive ion channel
CH57_RS06125	COG1196	nuclear chromosome segregation
CH57_RS06130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH57_RS06135	COG1309	transcriptional regulator
CH57_RS06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_RS06145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_RS06155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH57_RS06175	COG3695	enzyme binding
CH57_RS06180	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH57_RS06185	COG1946	Acyl-CoA thioesterase
CH57_RS06190	COG0004	ammonium transporteR
CH57_RS06195	COG0347	Belongs to the P(II) protein family
CH57_RS06200	COG1132	(ABC) transporter
CH57_RS06205	COG1132	(ABC) transporter
CH57_RS06210	COG1522	sequence-specific DNA binding
CH57_RS06225	COG4533	DNA binding
CH57_RS06235	COG0824	Thioesterase
CH57_RS06240	COG1555	photosystem II stabilization
CH57_RS06245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH57_RS06250	COG0776	regulation of translation
CH57_RS06255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH57_RS06280	COG0271	Belongs to the BolA IbaG family
CH57_RS06285	COG3056	Lipoprotein
CH57_RS06290	COG2223	nitrite transmembrane transporter activity
CH57_RS06300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH57_RS06305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH57_RS06310	COG1845	cytochrome c oxidase, subunit III
CH57_RS06315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH57_RS06325	COG2814	Major facilitator Superfamily
CH57_RS06335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH57_RS06340	COG0693	protein deglycase activity
CH57_RS06360	COG0142	geranyltranstransferase activity
CH57_RS06380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH57_RS06385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH57_RS06400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH57_RS06400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH57_RS06425	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH57_RS06430	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH57_RS06435	COG1862	Preprotein translocase
CH57_RS06455	COG0450	alkyl hydroperoxide reductase
CH57_RS06485	COG0366	Alpha amylase catalytic
CH57_RS06505	COG5002	protein histidine kinase activity
CH57_RS06510	COG0745	RESPONSE REGULATOR receiver
CH57_RS06520	COG0420	3'-5' exonuclease activity
CH57_RS06525	COG0419	ATPase involved in DNA repair
CH57_RS06540	COG1940	carbohydrate kinase activity
CH57_RS06575	COG2226	methyltransferase
CH57_RS06635	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH57_RS06655	COG1477	protein flavinylation
CH57_RS06675	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH57_RS06680	COG1805	sodium ion transport
CH57_RS06690	COG3034	peptidoglycan biosynthetic process
CH57_RS06695	COG0121	glutamine amidotransferase
CH57_RS06705	COG1960	acyl-CoA dehydrogenase activity
CH57_RS06715	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH57_RS06735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH57_RS06750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH57_RS06760	COG0765	amino acid transport
CH57_RS06800	COG2814	Major facilitator Superfamily
CH57_RS06805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH57_RS06815	COG1846	Transcriptional regulator
CH57_RS06820	COG1566	PFAM secretion protein HlyD family protein
CH57_RS06825	COG2814	Major facilitator Superfamily
CH57_RS06830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH57_RS06835	COG3118	belongs to the thioredoxin family
CH57_RS06840	COG3148	PFAM DTW domain containing protein
CH57_RS06845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH57_RS06845	COG1042	CoA-binding domain protein
CH57_RS06845	COG0045	succinate-CoA ligase (ADP-forming) activity
CH57_RS06850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH57_RS06855	COG5544	Lipoprotein
CH57_RS06895	COG0542	response to heat
CH57_RS06905	COG0564	pseudouridine synthase activity
CH57_RS06910	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH57_RS06915	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH57_RS06930	COG1605	Chorismate mutase
CH57_RS06930	COG0077	Prephenate dehydratase
CH57_RS06950	COG0077	Prephenate dehydratase
CH57_RS06950	COG1605	Chorismate mutase
CH57_RS06955	COG0287	Prephenate dehydrogenase
CH57_RS06955	COG1605	Chorismate mutase
CH57_RS06960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH57_RS06965	COG3279	Response regulator of the LytR AlgR family
CH57_RS06970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_RS06975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_RS06980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_RS06985	COG3137	Salt-induced outer membrane protein
CH57_RS07020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH57_RS07025	COG4137	Cytochrome C assembly protein
CH57_RS07030	COG4536	flavin adenine dinucleotide binding
CH57_RS07045	COG4536	flavin adenine dinucleotide binding
CH57_RS07065	COG2918	glutathione biosynthetic process
CH57_RS07070	COG1238	metal cluster binding
CH57_RS07075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_RS07105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH57_RS07150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH57_RS07155	COG3958	Transketolase
CH57_RS07160	COG3959	Transketolase, thiamine diphosphate binding domain
CH57_RS07165	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS07170	COG1129	ABC transporter
CH57_RS07180	COG1879	ABC-type sugar transport system periplasmic component
CH57_RS07190	COG3783	Cytochrome b(562)
CH57_RS07195	COG3038	cytochrome b561
CH57_RS07200	COG3381	protein complex oligomerization
CH57_RS07205	COG3302	dmso reductase anchor subunit
CH57_RS07210	COG0437	4 iron, 4 sulfur cluster binding
CH57_RS07215	COG0243	molybdopterin cofactor binding
CH57_RS07220	COG0235	Class ii aldolase
CH57_RS07225	COG1349	DNA-binding transcription factor activity
CH57_RS07240	COG1129	ABC transporter
CH57_RS07245	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS07250	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS07255	COG3623	hexulose-6-phosphate isomerase
CH57_RS07260	COG1070	Carbohydrate kinase
CH57_RS07265	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH57_RS07265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH57_RS07275	COG0024	Methionine aminopeptidase
CH57_RS07295	COG4771	TonB-dependent receptor
CH57_RS07305	COG1858	cytochrome C peroxidase
CH57_RS07310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS07330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH57_RS07345	COG2376	Dihydroxyacetone kinase
CH57_RS07350	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS07355	COG1063	alcohol dehydrogenase
CH57_RS07360	COG0698	ribose 5-phosphate isomerase
CH57_RS07375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH57_RS07380	COG4942	peptidase
CH57_RS07380	COG1388	LysM domain
CH57_RS07420	COG0529	Catalyzes the synthesis of activated sulfate
CH57_RS07470	COG0720	synthase
CH57_RS07475	COG0602	queuosine metabolic process
CH57_RS07495	COG3956	TIGRFAM MazG family protein
CH57_RS07505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH57_RS07510	COG4999	Histidine kinase
CH57_RS07510	COG3850	Histidine kinase
CH57_RS07510	COG3437	response regulator, receiver
CH57_RS07510	COG2205	protein histidine kinase activity
CH57_RS07515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH57_RS07535	COG2860	membrane
CH57_RS07555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_RS07560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH57_RS07570	COG1120	ATPase activity
CH57_RS07575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH57_RS07580	COG1643	Atp-dependent helicase
CH57_RS07585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH57_RS07600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH57_RS07605	COG0617	tRNA 3'-terminal CCA addition
CH57_RS07610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH57_RS07630	COG0726	polysaccharide deacetylase
CH57_RS07635	COG0842	Transport permease protein
CH57_RS07640	COG1131	(ABC) transporter
CH57_RS07645	COG0288	reversible hydration of carbon dioxide
CH57_RS07650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH57_RS07655	COG2132	Multicopper oxidase
CH57_RS07675	COG0697	spore germination
CH57_RS07685	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH57_RS07700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH57_RS07705	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH57_RS07710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH57_RS07715	COG2186	Transcriptional regulator
CH57_RS07720	COG1113	amino acid transport
CH57_RS07725	COG3725	Membrane protein required for beta-lactamase induction
CH57_RS07730	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH57_RS07740	COG4969	Belongs to the N-Me-Phe pilin family
CH57_RS07745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH57_RS07750	COG1459	type II secretion system
CH57_RS07805	COG0582	viral genome integration into host DNA
CH57_RS07815	COG0795	lipopolysaccharide-transporting ATPase activity
CH57_RS07820	COG0795	lipopolysaccharide-transporting ATPase activity
CH57_RS07830	COG2927	DNA polymerase III (CHI subunit)
CH57_RS07835	COG0525	valine-tRNA ligase activity
CH57_RS07845	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH57_RS07855	COG2731	YhcH YjgK YiaL family protein
CH57_RS07865	COG0601	transmembrane transport
CH57_RS07870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_RS07875	COG0444	Belongs to the ABC transporter superfamily
CH57_RS07880	COG4608	Belongs to the ABC transporter superfamily
CH57_RS07895	COG2188	Transcriptional regulator
CH57_RS07900	COG3624	Phosphonate C-P lyase system protein PhnG
CH57_RS07905	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH57_RS07910	COG3626	phosphonate metabolism
CH57_RS07915	COG3627	carbon phosphorus lyase activity
CH57_RS07920	COG4107	phosphonate C-P lyase system protein PhnK
CH57_RS07925	COG4778	phosphonate C-P lyase system protein PhnL
CH57_RS07930	COG3454	Phosphonate metabolism
CH57_RS07935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH57_RS07940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH57_RS07945	COG0702	epimerase
CH57_RS07960	COG3842	ATPase activity
CH57_RS07965	COG0395	ABC-type sugar transport system, permease component
CH57_RS07970	COG1175	transmembrane transport
CH57_RS07975	COG1653	transport
CH57_RS07995	COG3153	acetyltransferase
CH57_RS08000	COG3154	lipid carrier protein
CH57_RS08010	COG0826	peptidase U32
CH57_RS08015	COG0826	peptidase U32
CH57_RS08025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_RS08035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH57_RS08055	COG0513	Belongs to the DEAD box helicase family
CH57_RS08070	COG2801	Transposase and inactivated derivatives
CH57_RS08100	COG0195	Participates in both transcription termination and antitermination
CH57_RS08120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH57_RS08130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH57_RS08145	COG1534	Rna-binding protein
CH57_RS08155	COG2027	D-alanyl-D-alanine carboxypeptidase
CH57_RS08160	COG0745	RESPONSE REGULATOR receiver
CH57_RS08165	COG0642	Histidine kinase
CH57_RS08175	COG0697	spore germination
CH57_RS08190	COG0142	geranyltranstransferase activity
CH57_RS08200	COG3423	Transcriptional regulator
CH57_RS08225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH57_RS08230	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH57_RS08235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH57_RS08240	COG2105	PFAM AIG2 family protein
CH57_RS08245	COG2911	Protein conserved in bacteria
CH57_RS08250	COG0729	surface antigen
CH57_RS08260	COG1253	flavin adenine dinucleotide binding
CH57_RS08270	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH57_RS08280	COG0737	Belongs to the 5'-nucleotidase family
CH57_RS08290	COG0545	Peptidyl-prolyl cis-trans isomerase
CH57_RS08295	COG3061	Opacity-associated protein A
CH57_RS08320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH57_RS08330	COG0360	Binds together with S18 to 16S ribosomal RNA
CH57_RS08340	COG1073	alpha beta
CH57_RS08355	COG0435	Glutathione S-transferase
CH57_RS08360	COG0583	DNA-binding transcription factor activity
CH57_RS08365	COG1741	Belongs to the pirin family
CH57_RS08370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH57_RS08390	COG2823	Periplasmic or secreted lipoprotein
CH57_RS08400	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH57_RS08410	COG2198	Histidine kinase
CH57_RS08410	COG5002	protein histidine kinase activity
CH57_RS08410	COG0784	Response regulator, receiver
CH57_RS08420	COG1242	4 iron, 4 sulfur cluster binding
CH57_RS08425	COG0069	glutamate synthase activity
CH57_RS08425	COG0067	glutamate synthase
CH57_RS08425	COG0070	glutamate synthase
CH57_RS08430	COG0493	'glutamate synthase
CH57_RS08440	COG2969	positive regulation of protein catabolic process
CH57_RS08445	COG0625	glutathione transferase activity
CH57_RS08465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH57_RS08470	COG3105	Protein conserved in bacteria
CH57_RS08475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH57_RS08485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH57_RS08495	COG5007	Belongs to the BolA IbaG family
CH57_RS08500	COG3113	response to antibiotic
CH57_RS08505	COG2854	intermembrane phospholipid transfer
CH57_RS08510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH57_RS08515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH57_RS08520	COG1127	ABC transporter
CH57_RS08525	COG0530	calcium, potassium:sodium antiporter activity
CH57_RS08530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH57_RS08530	COG0517	IMP dehydrogenase activity
CH57_RS08535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH57_RS08540	COG3117	lipopolysaccharide transmembrane transporter activity
CH57_RS08545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH57_RS08550	COG1137	ATPase activity
CH57_RS08555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH57_RS08575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS08610	COG1609	Transcriptional regulator
CH57_RS08615	COG1263	PTS System
CH57_RS08615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_RS08620	COG0366	Alpha amylase catalytic
CH57_RS08625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH57_RS08630	COG3783	Cytochrome b(562)
CH57_RS08640	COG0312	modulator of DNA gyrase
CH57_RS08650	COG2732	(Barnase) inhibitor
CH57_RS08665	COG1012	belongs to the aldehyde dehydrogenase family
CH57_RS08685	COG0583	DNA-binding transcription factor activity
CH57_RS08745	COG0312	modulator of DNA gyrase
CH57_RS08750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH57_RS08755	COG3164	Protein of unknown function
CH57_RS08760	COG1530	ribonuclease E activity
CH57_RS08765	COG0424	maF-like protein
CH57_RS08770	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH57_RS08775	COG1792	Involved in formation and maintenance of cell shape
CH57_RS08780	COG1077	Cell shape determining protein MreB Mrl
CH57_RS08785	COG2199	diguanylate cyclase activity
CH57_RS08785	COG2200	EAL domain
CH57_RS08790	COG0604	alcohol dehydrogenase
CH57_RS08795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH57_RS08810	COG0511	ligase activity, forming carbon-carbon bonds
CH57_RS08815	COG0439	Biotin carboxylase
CH57_RS08820	COG3924	membrane
CH57_RS08825	COG4145	pantothenate transmembrane transporter activity
CH57_RS08835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH57_RS08840	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH57_RS08865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH57_RS08875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH57_RS08880	COG3133	Outer membrane lipoprotein
CH57_RS08890	COG1278	Cold shock
CH57_RS08895	COG1278	Cold shock
CH57_RS08920	COG0625	glutathione transferase activity
CH57_RS08930	COG1069	ribulokinase activity
CH57_RS08940	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS08945	COG1129	ABC transporter
CH57_RS08955	COG1560	Kdo2-lipid A biosynthetic process
CH57_RS08965	COG0025	NhaP-type Na H and K H
CH57_RS08970	COG2252	PERMEase
CH57_RS08975	COG3077	Addiction module antitoxin, RelB DinJ family
CH57_RS08985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH57_RS08995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH57_RS09000	COG0431	NADPH-dependent FMN reductase
CH57_RS09005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH57_RS09010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_RS09015	COG1869	D-ribose catabolic process
CH57_RS09020	COG2207	Transcriptional regulator
CH57_RS09020	COG1917	Cupin 2, conserved barrel domain protein
CH57_RS09025	COG0673	inositol 2-dehydrogenase activity
CH57_RS09040	COG3209	COG3209 Rhs family protein
CH57_RS09050	COG3501	Rhs element vgr protein
CH57_RS09095	COG3501	Rhs element vgr protein
CH57_RS09170	COG2801	Transposase and inactivated derivatives
CH57_RS09230	COG1175	transmembrane transport
CH57_RS09235	COG3833	ABC-type maltose transport systems, permease component
CH57_RS09250	COG0527	aspartate kinase activity
CH57_RS09270	COG1414	Transcriptional regulator
CH57_RS09275	COG1414	Transcriptional regulator
CH57_RS09285	COG2224	Isocitrate lyase
CH57_RS09290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH57_RS09340	COG0151	Belongs to the GarS family
CH57_RS09360	COG1515	deoxyribonuclease V activity
CH57_RS09400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH57_RS09410	COG2022	thiamine diphosphate biosynthetic process
CH57_RS09465	COG0250	Participates in transcription elongation, termination and antitermination
CH57_RS09525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH57_RS09560	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH57_RS09565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH57_RS09570	COG1739	Uncharacterized protein family UPF0029
CH57_RS09580	COG1739	Uncharacterized protein family UPF0029
CH57_RS09605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH57_RS09645	COG0805	protein transport
CH57_RS09655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH57_RS09675	COG1322	Protein conserved in bacteria
CH57_RS09680	COG0586	Pfam SNARE associated Golgi protein
CH57_RS09685	COG1966	Carbon starvation protein
CH57_RS09700	COG0412	Dienelactone hydrolase
CH57_RS09710	COG0583	DNA-binding transcription factor activity
CH57_RS09715	COG0697	spore germination
CH57_RS09720	COG0679	Auxin Efflux Carrier
CH57_RS09725	COG0584	glycerophosphoryl diester phosphodiesterase
CH57_RS09785	COG0410	ABC transporter
CH57_RS09795	COG4177	L-phenylalanine transmembrane transporter activity
CH57_RS09805	COG0683	leucine binding
CH57_RS09830	COG2177	Part of the ABC transporter FtsEX involved in
CH57_RS09835	COG2884	Cell division ATP-binding protein ftsE
CH57_RS09840	COG0552	protein localization to endoplasmic reticulum
CH57_RS09840	COG0552	protein localization to endoplasmic reticulum
CH57_RS09850	COG0742	ribosomal rna small subunit methyltransferase
CH57_RS09855	COG3776	membrane
CH57_RS09870	COG3714	YhhN family
CH57_RS09885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH57_RS09895	COG0247	lactate metabolic process
CH57_RS09905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH57_RS09915	COG0584	glycerophosphoryl diester phosphodiesterase
CH57_RS09925	COG0561	phosphatase activity
CH57_RS09930	COG2267	carboxylic ester hydrolase activity
CH57_RS09935	COG1280	lysine exporter protein (LysE YggA)
CH57_RS09940	COG1280	lysine exporter protein (LysE YggA)
CH57_RS09945	COG0514	ATP-dependent DNA helicase (RecQ)
CH57_RS09950	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH57_RS09955	COG2050	protein possibly involved in aromatic compounds catabolism
CH57_RS09970	COG5564	TIM-barrel signal transduction protein
CH57_RS09975	COG5441	Belongs to the UPF0261 family
CH57_RS09985	COG0210	DNA helicase
CH57_RS09990	COG1011	Hydrolase
CH57_RS09995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH57_RS10000	COG3159	Protein conserved in bacteria
CH57_RS10020	COG3072	Adenylate cyclase
CH57_RS10035	COG1587	Uroporphyrinogen-III synthase
CH57_RS10040	COG2959	enzyme of heme biosynthesis
CH57_RS10045	COG3071	HemY protein
CH57_RS10090	COG1113	amino acid transport
CH57_RS10110	COG2244	polysaccharide biosynthetic process
CH57_RS10115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH57_RS10120	COG0456	acetyltransferase
CH57_RS10125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH57_RS10130	COG1088	dTDP-glucose 4,6-dehydratase activity
CH57_RS10135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH57_RS10140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH57_RS10145	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH57_RS10150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH57_RS10155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH57_RS10160	COG3118	belongs to the thioredoxin family
CH57_RS10190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH57_RS10200	COG3328	transposase activity
CH57_RS10215	COG3121	Chaperone
CH57_RS10230	COG3121	Chaperone
CH57_RS10270	COG0583	DNA-binding transcription factor activity
CH57_RS10315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH57_RS10320	COG3978	acetolactate synthase activity
CH57_RS10335	COG3085	chromosome segregation
CH57_RS10345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS10350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS10355	COG1129	ABC transporter
CH57_RS10360	COG1879	ABC-type sugar transport system periplasmic component
CH57_RS10440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH57_RS10440	COG0678	peroxiredoxin activity
CH57_RS10445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH57_RS10470	COG1629	transport
CH57_RS10490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH57_RS10520	COG2801	Transposase and inactivated derivatives
CH57_RS10540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH57_RS10545	COG0058	SHG alpha-glucan phosphorylase activity
CH57_RS10570	COG3275	phosphorelay sensor kinase activity
CH57_RS10600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH57_RS10605	COG2095	MarC family integral membrane protein
CH57_RS10625	COG3265	gluconokinase activity
CH57_RS10630	COG2610	gluconate transmembrane transporter activity
CH57_RS10635	COG1609	Transcriptional regulator
CH57_RS10640	COG1741	Belongs to the pirin family
CH57_RS10660	COG0191	fructose-bisphosphate aldolase activity
CH57_RS10675	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS10690	COG2081	HI0933 family
CH57_RS10695	COG0306	phosphate transporter
CH57_RS10715	COG0589	response to stress
CH57_RS10735	COG0339	signal peptide processing
CH57_RS10740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH57_RS10745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH57_RS10750	COG3835	regulator
CH57_RS10755	COG2610	gluconate transmembrane transporter activity
CH57_RS10760	COG1929	Belongs to the glycerate kinase type-1 family
CH57_RS10785	COG1295	ribonuclease BN
CH57_RS10790	COG2134	cdp-diacylglycerol pyrophosphatase
CH57_RS10795	COG2982	Protein involved in outer membrane biogenesis
CH57_RS10800	COG2200	EAL domain
CH57_RS10805	COG1942	4-Oxalocrotonate Tautomerase
CH57_RS10810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_RS10815	COG0612	Peptidase, M16
CH57_RS10835	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH57_RS10840	COG2199	diguanylate cyclase activity
CH57_RS10840	COG2200	EAL domain
CH57_RS10845	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH57_RS10850	COG4608	Belongs to the ABC transporter superfamily
CH57_RS10855	COG0444	Belongs to the ABC transporter superfamily
CH57_RS10860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH57_RS10865	COG0601	transmembrane transport
CH57_RS10870	COG0747	negative chemotaxis
CH57_RS10880	COG2831	hemolysin activation secretion protein
CH57_RS10895	COG2271	Major facilitator Superfamily
CH57_RS10900	COG3851	Histidine kinase
CH57_RS10905	COG2197	response regulator
CH57_RS10910	COG2194	sulfuric ester hydrolase activity
CH57_RS10925	COG2986	histidine ammonia-lyase
CH57_RS10955	COG4607	ABC-type enterochelin transport system periplasmic component
CH57_RS10965	COG4605	iron ion homeostasis
CH57_RS10970	COG4604	ABC transporter, ATP-binding protein
CH57_RS11010	COG0582	viral genome integration into host DNA
CH57_RS11015	COG1609	Transcriptional regulator
CH57_RS11015	COG2207	Transcriptional regulator
CH57_RS11020	COG4214	carbohydrate transport
CH57_RS11030	COG4213	ABC transporter substrate-binding protein
CH57_RS11040	COG1070	Carbohydrate kinase
CH57_RS11050	COG3121	Chaperone
CH57_RS11070	COG3274	enterobacterial common antigen metabolic process
CH57_RS11120	COG3276	selenocysteine insertion sequence binding
CH57_RS11125	COG3276	selenocysteine insertion sequence binding
CH57_RS11140	COG2864	formate dehydrogenase
CH57_RS11145	COG0437	4 iron, 4 sulfur cluster binding
CH57_RS11150	COG3383	formate dehydrogenase (NAD+) activity
CH57_RS11150	COG0243	molybdopterin cofactor binding
CH57_RS11155	COG3383	formate dehydrogenase (NAD+) activity
CH57_RS11155	COG0243	molybdopterin cofactor binding
CH57_RS11165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH57_RS11190	COG3722	fumarate hydratase activity
CH57_RS11200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS11200	COG2213	PTS system mannitol-specific
CH57_RS11220	COG2818	Glycosylase
CH57_RS11230	COG2885	chlorophyll binding
CH57_RS11245	COG0366	Alpha amylase catalytic
CH57_RS11255	COG3977	Valine--pyruvate aminotransferase
CH57_RS11275	COG5645	(Lipo)protein
CH57_RS11280	COG0823	Involved in the tonB-independent uptake of proteins
CH57_RS11285	COG0823	Involved in the tonB-independent uptake of proteins
CH57_RS11290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH57_RS11295	COG2423	ornithine cyclodeaminase activity
CH57_RS11305	COG2801	Transposase and inactivated derivatives
CH57_RS11310	COG2801	Transposase and inactivated derivatives
CH57_RS11315	COG0561	phosphatase activity
CH57_RS11320	COG0187	DNA topoisomerase II activity
CH57_RS11335	COG0592	DNA-directed DNA polymerase activity
CH57_RS11345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH57_RS11355	COG0706	membrane insertase activity
CH57_RS11380	COG2252	PERMEase
CH57_RS11385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH57_RS11390	COG0765	amino acid transport
CH57_RS11395	COG0765	amino acid transport
CH57_RS11400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS11410	COG0704	Plays a role in the regulation of phosphate uptake
CH57_RS11420	COG0581	inorganic phosphate transmembrane transporter activity
CH57_RS11425	COG0573	inorganic phosphate transmembrane transporter activity
CH57_RS11430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH57_RS11485	COG3312	ion transport
CH57_RS11500	COG0716	FMN binding
CH57_RS11505	COG1522	sequence-specific DNA binding
CH57_RS11535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_RS11545	COG0477	Major facilitator Superfamily
CH57_RS11550	COG2186	Transcriptional regulator
CH57_RS11580	COG3328	transposase activity
CH57_RS11585	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH57_RS11595	COG3084	Protein conserved in bacteria
CH57_RS11600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH57_RS11605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH57_RS11610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH57_RS11610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH57_RS11635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH57_RS11645	COG3852	Histidine kinase
CH57_RS11650	COG0174	glutamine synthetase
CH57_RS11665	COG1011	Hydrolase
CH57_RS11690	COG0456	acetyltransferase
CH57_RS11695	COG2982	Protein involved in outer membrane biogenesis
CH57_RS11700	COG2233	PERMEase
CH57_RS11705	COG0786	glutamate:sodium symporter activity
CH57_RS11710	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH57_RS11715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH57_RS11720	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH57_RS11740	COG2860	membrane
CH57_RS11745	COG1561	YicC-like family, N-terminal region
CH57_RS11770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH57_RS11805	COG1519	Transferase
CH57_RS11810	COG0859	PFAM glycosyl transferase family 9
CH57_RS11815	COG0859	PFAM glycosyl transferase family 9
CH57_RS11825	COG0156	8-amino-7-oxononanoate synthase activity
CH57_RS11840	COG4942	peptidase
CH57_RS11850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH57_RS11855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH57_RS11875	COG1045	serine acetyltransferase
CH57_RS11880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH57_RS11885	COG2169	Transcriptional regulator
CH57_RS11885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH57_RS11890	COG2205	protein histidine kinase activity
CH57_RS11895	COG0745	RESPONSE REGULATOR receiver
CH57_RS11900	COG3678	ATP-independent chaperone mediated protein folding
CH57_RS11920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH57_RS11930	COG0471	metal ion transport
CH57_RS11935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH57_RS11940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH57_RS11945	COG0583	DNA-binding transcription factor activity
CH57_RS11960	COG3152	Membrane
CH57_RS11970	COG1494	fructose-1,6-bisphosphatase
CH57_RS11975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH57_RS11980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH57_RS12050	COG1575	Belongs to the MenA family. Type 1 subfamily
CH57_RS12065	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH57_RS12070	COG1609	Transcriptional regulator
CH57_RS12080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH57_RS12090	COG4682	membrane
CH57_RS12110	COG0527	aspartate kinase activity
CH57_RS12110	COG0460	homoserine dehydrogenase
CH57_RS12120	COG2801	Transposase and inactivated derivatives
CH57_RS12130	COG1349	DNA-binding transcription factor activity
CH57_RS12140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH57_RS12150	COG0058	SHG alpha-glucan phosphorylase activity
CH57_RS12155	COG0058	SHG alpha-glucan phosphorylase activity
CH57_RS12160	COG1640	4-alpha-glucanotransferase
CH57_RS12195	COG1918	ferrous iron import across plasma membrane
CH57_RS12205	COG2183	response to ionizing radiation
CH57_RS12210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH57_RS12235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH57_RS12240	COG1011	Hydrolase
CH57_RS12255	COG0494	nUDIX hydrolase
CH57_RS12260	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH57_RS12290	COG4796	Type ii and iii secretion system protein
CH57_RS12315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH57_RS12320	COG0546	phosphoglycolate phosphatase activity
CH57_RS12325	COG0180	Tryptophanyl-tRNA synthetase
CH57_RS12345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH57_RS12350	COG0402	S-adenosylhomocysteine deaminase activity
CH57_RS12380	COG1486	melibiose metabolic process
CH57_RS12385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH57_RS12390	COG0433	COG0433 Predicted ATPase
CH57_RS12405	COG1289	transmembrane transporter activity
CH57_RS12415	COG1765	OsmC-like protein
CH57_RS12425	COG3954	Phosphoribulokinase
CH57_RS12435	COG0429	hydrolase of the alpha beta-hydrolase fold
CH57_RS12445	COG4521	taurine ABC transporter
CH57_RS12455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH57_RS12460	COG2175	clavaminate synthase activity
CH57_RS12470	COG1216	Glycosyl transferase, family 2
CH57_RS12490	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH57_RS12495	COG1047	Peptidyl-prolyl cis-trans
CH57_RS12505	COG0545	Peptidyl-prolyl cis-trans isomerase
CH57_RS12510	COG2964	Protein conserved in bacteria
CH57_RS12530	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH57_RS12535	COG0049	tRNA binding
CH57_RS12565	COG0051	transcription antitermination factor activity, RNA binding
CH57_RS12580	COG0089	rRNA binding
CH57_RS12590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH57_RS12600	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH57_RS12605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH57_RS12615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH57_RS12620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH57_RS12660	COG1841	ribosomal large subunit assembly
CH57_RS12670	COG0201	protein transport
CH57_RS12675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH57_RS12690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH57_RS12705	COG0789	Transcriptional regulator
CH57_RS12710	COG3036	rescue of stalled ribosome
CH57_RS12740	COG0758	DNA mediated transformation
CH57_RS12750	COG0551	DNA topoisomerase type I activity
CH57_RS12765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH57_RS12790	COG3162	membrane
CH57_RS12800	COG1301	dicarboxylic acid transport
CH57_RS12910	COG2391	methyltransferase activity
CH57_RS12915	COG0425	Belongs to the sulfur carrier protein TusA family
CH57_RS12920	COG0583	DNA-binding transcription factor activity
CH57_RS12925	COG0814	amino acid
CH57_RS12930	COG0626	cystathionine gamma-synthase activity
CH57_RS12940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_RS12945	COG4558	Periplasmic binding protein
CH57_RS12950	COG3720	iron ion transport
CH57_RS12955	COG4771	TonB-dependent receptor
CH57_RS12960	COG0702	epimerase
CH57_RS12965	COG3721	Heme iron utilization protein
CH57_RS12990	COG1358	cellular component organization or biogenesis
CH57_RS13050	COG3121	Chaperone
CH57_RS13095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH57_RS13105	COG0735	belongs to the Fur family
CH57_RS13110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH57_RS13135	COG1448	Aminotransferase
CH57_RS13140	COG2315	Protein conserved in bacteria
CH57_RS13145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH57_RS13150	COG0629	single-stranded DNA binding
CH57_RS13160	COG1454	alcohol dehydrogenase
CH57_RS13230	COG1309	transcriptional regulator
CH57_RS13235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_RS13235	COG0493	'glutamate synthase
CH57_RS13240	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH57_RS13245	COG3383	formate dehydrogenase (NAD+) activity
CH57_RS13260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH57_RS13315	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH57_RS13325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH57_RS13330	COG1053	succinate dehydrogenase
CH57_RS13345	COG3264	Mechanosensitive ion channel
CH57_RS13345	COG1511	domain protein
CH57_RS13365	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH57_RS13380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH57_RS13385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH57_RS13385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH57_RS13390	COG0802	atpase or kinase
CH57_RS13395	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH57_RS13415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH57_RS13420	COG0330	HflC and HflK could
CH57_RS13425	COG0330	HflC and HflK could
CH57_RS13430	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH57_RS13445	COG0557	exoribonuclease II activity
CH57_RS13450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH57_RS13455	COG1960	acyl-CoA dehydrogenase activity
CH57_RS13460	COG3650	response to hydrogen peroxide
CH57_RS13480	COG1401	restriction endodeoxyribonuclease activity
CH57_RS13495	COG2963	transposase activity
CH57_RS13550	COG4269	membrane
CH57_RS13560	COG2207	Transcriptional regulator
CH57_RS13565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_RS13570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_RS13575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_RS13580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS13580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH57_RS13580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS13630	COG1070	Carbohydrate kinase
CH57_RS13635	COG0859	PFAM glycosyl transferase family 9
CH57_RS13655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_RS13660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH57_RS13705	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH57_RS13710	COG0456	acetyltransferase
CH57_RS13720	COG2823	Periplasmic or secreted lipoprotein
CH57_RS13730	COG4667	esterase of the alpha-beta hydrolase superfamily
CH57_RS13735	COG0084	hydrolase, TatD family'
CH57_RS13740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH57_RS13780	COG3726	membrane protein affecting hemolysin expression
CH57_RS13785	COG0560	Phosphoserine phosphatase
CH57_RS13810	COG2885	chlorophyll binding
CH57_RS13815	COG2199	diguanylate cyclase activity
CH57_RS13830	COG0741	lytic transglycosylase activity
CH57_RS13835	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH57_RS13850	COG2207	Transcriptional regulator
CH57_RS13850	COG3708	Transcriptional regulator
CH57_RS13855	COG3045	CreA protein
CH57_RS13860	COG0745	RESPONSE REGULATOR receiver
CH57_RS13890	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH57_RS13905	COG1584	GPR1 FUN34 yaaH family protein
CH57_RS13925	COG0583	DNA-binding transcription factor activity
CH57_RS13940	COG0196	riboflavin kinase activity
CH57_RS13955	COG1047	Peptidyl-prolyl cis-trans
CH57_RS13990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH57_RS13995	COG1280	lysine exporter protein (LysE YggA)
CH57_RS14000	COG2966	Psort location CytoplasmicMembrane, score
CH57_RS14010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH57_RS14060	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH57_RS14065	COG0564	pseudouridine synthase activity
CH57_RS14155	COG2885	chlorophyll binding
CH57_RS14155	COG3047	cAMP biosynthetic process
CH57_RS14175	COG0417	DNA replication proofreading
CH57_RS14180	COG0586	Pfam SNARE associated Golgi protein
CH57_RS14185	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CH57_RS14190	COG1178	ABC-type Fe3 transport system permease component
CH57_RS14195	COG4143	(ABC) transporter
CH57_RS14215	COG2814	Major facilitator Superfamily
CH57_RS14235	COG2814	Major facilitator Superfamily
CH57_RS14250	COG0473	3-isopropylmalate dehydrogenase activity
CH57_RS14280	COG1022	Amp-dependent synthetase and ligase
CH57_RS14290	COG0028	Belongs to the TPP enzyme family
CH57_RS14310	COG1609	Transcriptional regulator
CH57_RS14330	COG3116	cell division
CH57_RS14335	COG0768	penicillin binding
CH57_RS14340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH57_RS14345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH57_RS14360	COG0772	Belongs to the SEDS family
CH57_RS14380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH57_RS14385	COG0849	cell division
CH57_RS14390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH57_RS14415	COG0494	nUDIX hydrolase
CH57_RS14430	COG0435	Glutathione S-transferase
CH57_RS14435	COG2259	Doxx family
CH57_RS14445	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH57_RS14450	COG4575	ribosome binding
CH57_RS14470	COG0586	Pfam SNARE associated Golgi protein
CH57_RS14485	COG2271	Major facilitator Superfamily
CH57_RS14505	COG2721	sulfolactate sulfo-lyase activity
CH57_RS14525	COG0673	inositol 2-dehydrogenase activity
CH57_RS14530	COG1451	nucleotide metabolic process
CH57_RS14545	COG1902	pentaerythritol trinitrate reductase activity
CH57_RS14545	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH57_RS14550	COG3247	response to pH
CH57_RS14570	COG4245	von Willebrand factor, type A
CH57_RS14585	COG4245	von Willebrand factor, type A
CH57_RS14590	COG2831	hemolysin activation secretion protein
CH57_RS14595	COG3210	domain, Protein
CH57_RS14620	COG3210	domain, Protein
CH57_RS14625	COG3210	domain, Protein
CH57_RS14645	COG3842	ATPase activity
CH57_RS14650	COG3459	Glycosyltransferase 36 associated
CH57_RS14655	COG1609	Transcriptional regulator
CH57_RS14660	COG2182	Extracellular solute-binding protein
CH57_RS14670	COG0395	ABC-type sugar transport system, permease component
CH57_RS14690	COG1289	transmembrane transporter activity
CH57_RS14715	COG0436	Aminotransferase
CH57_RS14735	COG0251	oxidation-reduction process
CH57_RS14830	COG0358	DNA primase activity
CH57_RS14835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH57_RS14850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH57_RS14865	COG4991	sh3 domain protein
CH57_RS14870	COG3025	triphosphatase activity
CH57_RS14885	COG0531	amino acid
CH57_RS14905	COG3384	dioxygenase
CH57_RS14910	COG0754	glutathionylspermidine amidase activity
CH57_RS14925	COG1538	Outer membrane efflux protein
CH57_RS14930	COG0494	nUDIX hydrolase
CH57_RS14935	COG3151	Protein conserved in bacteria
CH57_RS14940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH57_RS14945	COG3150	esterase
CH57_RS14955	COG0583	DNA-binding transcription factor activity
CH57_RS14960	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH57_RS14965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH57_RS14975	COG2132	Multicopper oxidase
CH57_RS14985	COG0656	L-ascorbic acid biosynthetic process
CH57_RS14995	COG1979	alcohol dehydrogenase
CH57_RS15000	COG2207	Transcriptional regulator
CH57_RS15005	COG0586	Pfam SNARE associated Golgi protein
CH57_RS15010	COG0626	cystathionine gamma-synthase activity
CH57_RS15015	COG0811	peptide transport
CH57_RS15020	COG0848	biopolymer transport protein
CH57_RS15070	COG4964	Belongs to the GSP D family
CH57_RS15075	COG4964	Belongs to the GSP D family
CH57_RS15115	COG4592	Periplasmic binding protein
CH57_RS15135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH57_RS15140	COG1684	flagellar biosynthetic protein fliR
CH57_RS15145	COG1987	bacterial-type flagellum assembly
CH57_RS15170	COG1677	Flagellar hook-basal body complex protein FliE
CH57_RS15210	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH57_RS15215	COG1815	bacterial-type flagellum-dependent cell motility
CH57_RS15220	COG1558	bacterial-type flagellum-dependent cell motility
CH57_RS15225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH57_RS15230	COG1749	Flagellar hook protein flgE
CH57_RS15255	COG4786	Flagellar basal body rod
CH57_RS15265	COG1706	bacterial-type flagellum-dependent cell motility
CH57_RS15275	COG1256	bacterial-type flagellum assembly
CH57_RS15295	COG3710	Transcriptional regulator
CH57_RS15315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH57_RS15340	COG1191	sigma factor activity
CH57_RS15345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH57_RS15390	COG2801	Transposase and inactivated derivatives
CH57_RS15405	COG0471	metal ion transport
CH57_RS15420	COG3209	COG3209 Rhs family protein
CH57_RS15430	COG3501	Rhs element vgr protein
CH57_RS15445	COG2610	gluconate transmembrane transporter activity
CH57_RS15460	COG1132	(ABC) transporter
CH57_RS15465	COG1132	(ABC) transporter
CH57_RS15465	COG2375	cellular response to nickel ion
CH57_RS15490	COG2226	methyltransferase
CH57_RS15490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH57_RS15490	COG3433	isochorismatase activity
CH57_RS15500	COG2226	methyltransferase
CH57_RS15500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH57_RS15500	COG3433	isochorismatase activity
CH57_RS15560	COG0667	Aldo Keto reductase
CH57_RS15590	COG1609	Transcriptional regulator
CH57_RS15600	COG0583	DNA-binding transcription factor activity
CH57_RS15605	COG2814	Major facilitator Superfamily
CH57_RS15610	COG0583	DNA-binding transcription factor activity
CH57_RS15625	COG0840	transmembrane signaling receptor activity
CH57_RS15695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH57_RS15715	COG0288	reversible hydration of carbon dioxide
CH57_RS15770	COG3119	arylsulfatase activity
CH57_RS15775	COG1349	DNA-binding transcription factor activity
CH57_RS15785	COG2222	sugar isomerase
CH57_RS15790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_RS15795	COG3715	PTS system
CH57_RS15800	COG3716	PTS system mannose fructose sorbose family IID component
CH57_RS15805	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS15815	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS15825	COG0641	radical SAM
CH57_RS15830	COG3119	arylsulfatase activity
CH57_RS15860	COG2271	Major facilitator Superfamily
CH57_RS15880	COG1263	PTS System
CH57_RS15880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_RS15885	COG1874	Beta-galactosidase
CH57_RS15890	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH57_RS15895	COG3833	ABC-type maltose transport systems, permease component
CH57_RS15900	COG1175	transmembrane transport
CH57_RS15905	COG2182	Extracellular solute-binding protein
CH57_RS15915	COG1129	ABC transporter
CH57_RS15920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS15925	COG1879	ABC-type sugar transport system periplasmic component
CH57_RS15935	COG0791	NLP P60 protein
CH57_RS15940	COG1695	Transcriptional regulator
CH57_RS16035	COG2944	sequence-specific DNA binding
CH57_RS16065	COG0582	viral genome integration into host DNA
CH57_RS16085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH57_RS16090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH57_RS16095	COG4974	Belongs to the 'phage' integrase family
CH57_RS16100	COG0716	FMN binding
CH57_RS16105	COG4452	Inner membrane protein CreD
CH57_RS16110	COG2205	protein histidine kinase activity
CH57_RS16115	COG0745	RESPONSE REGULATOR receiver
CH57_RS16140	COG1272	protein, Hemolysin III
CH57_RS16150	COG5295	Hep Hag repeat protein
CH57_RS16180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH57_RS16185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH57_RS16190	COG0006	proline dipeptidase activity
CH57_RS16205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH57_RS16210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH57_RS16245	COG0191	fructose-bisphosphate aldolase activity
CH57_RS16275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH57_RS16280	COG0501	Belongs to the peptidase M48B family
CH57_RS16290	COG1166	arginine decarboxylase activity
CH57_RS16300	COG3091	SprT-like family
CH57_RS16305	COG2356	endonuclease I
CH57_RS16310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH57_RS16315	COG0189	ligase activity
CH57_RS16330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH57_RS16340	COG2805	Type II/IV secretion system protein
CH57_RS16345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH57_RS16350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH57_RS16355	COG0762	integral membrane protein
CH57_RS16365	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH57_RS16370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH57_RS16375	COG3064	Membrane
CH57_RS16375	COG1073	alpha beta
CH57_RS16375	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH57_RS16395	COG3171	Protein conserved in bacteria
CH57_RS16405	COG1194	a g-specific adenine glycosylase
CH57_RS16425	COG4774	siderophore transport
CH57_RS16430	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS16435	COG1129	ABC transporter
CH57_RS16440	COG1879	ABC-type sugar transport system periplasmic component
CH57_RS16445	COG1982	Orn Lys Arg decarboxylase major
CH57_RS16580	COG3916	Acyl-homoserine-lactone synthase
CH57_RS16585	COG2771	luxR family
CH57_RS16635	COG2211	Major facilitator Superfamily
CH57_RS16645	COG2801	Transposase and inactivated derivatives
CH57_RS16650	COG5001	Diguanylate cyclase
CH57_RS16660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_RS16700	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH57_RS16705	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH57_RS16710	COG4771	TonB-dependent receptor
CH57_RS16745	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH57_RS16755	COG1074	ATP-dependent DNA helicase activity
CH57_RS16760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH57_RS16770	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH57_RS16785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH57_RS16790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH57_RS16795	COG2166	iron-sulfur cluster assembly
CH57_RS16800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH57_RS16805	COG0583	DNA-binding transcription factor activity
CH57_RS16810	COG2363	Small membrane protein
CH57_RS16825	COG1611	Belongs to the LOG family
CH57_RS16845	COG3098	single-species biofilm formation
CH57_RS16850	COG0564	pseudouridine synthase activity
CH57_RS16910	COG0575	Belongs to the CDS family
CH57_RS16915	COG0750	zinc metalloprotease
CH57_RS16930	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH57_RS16955	COG0587	DNA-directed DNA polymerase activity
CH57_RS16965	COG0346	lactoylglutathione lyase activity
CH57_RS16970	COG0037	tRNA processing
CH57_RS16980	COG4568	rho-dependent transcription termination
CH57_RS16990	COG4681	YaeQ
CH57_RS17000	COG3015	lipoprotein NlpE involved in copper resistance
CH57_RS17010	COG1720	tRNA m6t6A37 methyltransferase activity
CH57_RS17020	COG1464	Belongs to the NlpA lipoprotein family
CH57_RS17025	COG2011	ABC-type metal ion transport system permease component
CH57_RS17035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH57_RS17070	COG0656	L-ascorbic acid biosynthetic process
CH57_RS17085	COG0741	lytic transglycosylase activity
CH57_RS17085	COG1388	LysM domain
CH57_RS17090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH57_RS17095	COG2226	methyltransferase
CH57_RS17115	COG1953	Uracil, thiamine, allantoin
CH57_RS17145	COG3657	addiction module killer protein
CH57_RS17205	COG0582	viral genome integration into host DNA
CH57_RS17225	COG2867	negative regulation of translational initiation
CH57_RS17235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH57_RS17240	COG0497	DNA recombination
CH57_RS17245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH57_RS17260	COG2009	succinate dehydrogenase
CH57_RS17265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH57_RS17270	COG1053	succinate dehydrogenase
CH57_RS17280	COG0567	Dehydrogenase, E1 component
CH57_RS17285	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH57_RS17295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH57_RS17300	COG1271	oxidase subunit
CH57_RS17305	COG1294	oxidase, subunit
CH57_RS17310	COG4890	Cyd operon protein YbgT
CH57_RS17315	COG3790	cyd operon protein YbgE
CH57_RS17320	COG0824	Thioesterase
CH57_RS17325	COG0811	peptide transport
CH57_RS17330	COG0848	biopolymer transport protein
CH57_RS17335	COG3064	Membrane
CH57_RS17335	COG3064	Membrane
CH57_RS17345	COG2885	chlorophyll binding
CH57_RS17350	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH57_RS17380	COG1230	cation diffusion facilitator family transporter
CH57_RS17385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH57_RS17400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH57_RS17415	COG2017	converts alpha-aldose to the beta-anomer
CH57_RS17430	COG1085	galactose-1-phosphate uridylyltransferase
CH57_RS17435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH57_RS17450	COG1119	ATPase activity
CH57_RS17455	COG2005	Transcriptional regulator
CH57_RS17455	COG3585	molybdate ion transport
CH57_RS17465	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH57_RS17470	COG4149	molybdate abc transporter
CH57_RS17480	COG0561	phosphatase activity
CH57_RS17505	COG2226	methyltransferase
CH57_RS17515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CH57_RS17525	COG4628	conserved protein (DUF2132)
CH57_RS17530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH57_RS17540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH57_RS17550	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH57_RS17555	COG0314	molybdopterin synthase activity
CH57_RS17560	COG0670	Belongs to the BI1 family
CH57_RS17590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH57_RS17595	COG0583	DNA-binding transcription factor activity
CH57_RS17605	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH57_RS17610	COG2211	Major facilitator Superfamily
CH57_RS17625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH57_RS17635	COG1686	Belongs to the peptidase S11 family
CH57_RS17640	COG0277	FAD linked oxidase domain protein
CH57_RS17660	COG2261	transglycosylase associated protein
CH57_RS17670	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH57_RS17685	COG4807	Protein conserved in bacteria
CH57_RS17705	COG1122	ATPase activity
CH57_RS17725	COG2897	thiosulfate sulfurtransferase activity
CH57_RS17730	COG1732	Glycine betaine
CH57_RS17735	COG1732	Glycine betaine
CH57_RS17740	COG1174	glycine betaine transport
CH57_RS17745	COG1125	glycine betaine transport
CH57_RS17750	COG1174	glycine betaine transport
CH57_RS17755	COG0531	amino acid
CH57_RS17760	COG1982	Orn Lys Arg decarboxylase major
CH57_RS17770	COG0697	spore germination
CH57_RS17795	COG0814	amino acid
CH57_RS17810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_RS17840	COG0784	Response regulator, receiver
CH57_RS17840	COG2205	protein histidine kinase activity
CH57_RS17850	COG2198	Histidine kinase
CH57_RS17850	COG0642	Histidine kinase
CH57_RS17855	COG2198	Histidine kinase
CH57_RS17855	COG0642	Histidine kinase
CH57_RS17860	COG2223	nitrite transmembrane transporter activity
CH57_RS17900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH57_RS17945	COG3395	kinase activity
CH57_RS17955	COG1349	DNA-binding transcription factor activity
CH57_RS17960	COG3622	Belongs to the hyi family
CH57_RS17980	COG4386	tail sheath protein
CH57_RS18020	COG3299	homolog of phage Mu protein gp47
CH57_RS18040	COG1737	Transcriptional regulator
CH57_RS18045	COG2723	6-phospho-beta-galactosidase activity
CH57_RS18065	COG3157	Type VI secretion system effector, Hcp
CH57_RS18080	COG3083	sulfuric ester hydrolase activity
CH57_RS18085	COG3082	Protein of unknown function (DUF1414)
CH57_RS18105	COG1061	Type III restriction enzyme res subunit
CH57_RS18110	COG1187	pseudouridine synthase activity
CH57_RS18115	COG2814	Major facilitator Superfamily
CH57_RS18125	COG4172	Belongs to the ABC transporter superfamily
CH57_RS18130	COG4239	(ABC) transporter, permease
CH57_RS18135	COG4174	ABC transporter (Permease)
CH57_RS18140	COG4166	transmembrane transport
CH57_RS18145	COG2200	EAL domain
CH57_RS18150	COG0791	NLP P60 protein
CH57_RS18155	COG0671	phosphoesterase, PA-phosphatase related
CH57_RS18160	COG0523	cobalamin synthesis protein
CH57_RS18170	COG2186	Transcriptional regulator
CH57_RS18175	COG0246	Mannitol dehydrogenase
CH57_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS18235	COG1129	ABC transporter
CH57_RS18245	COG0494	nUDIX hydrolase
CH57_RS18255	COG1105	Belongs to the carbohydrate kinase PfkB family
CH57_RS18260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_RS18260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH57_RS18260	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH57_RS18265	COG3710	Transcriptional regulator
CH57_RS18280	COG3121	Chaperone
CH57_RS18285	COG3188	usher protein
CH57_RS18295	COG2855	membrane
CH57_RS18300	COG0583	DNA-binding transcription factor activity
CH57_RS18305	COG0833	amino acid
CH57_RS18315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_RS18325	COG4771	TonB-dependent receptor
CH57_RS18330	COG0625	glutathione transferase activity
CH57_RS18355	COG2011	ABC-type metal ion transport system permease component
CH57_RS18360	COG1686	Belongs to the peptidase S11 family
CH57_RS18375	COG1349	DNA-binding transcription factor activity
CH57_RS18385	COG0671	phosphoesterase, PA-phosphatase related
CH57_RS18420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH57_RS18425	COG3842	ATPase activity
CH57_RS18430	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH57_RS18435	COG1177	transmembrane transport
CH57_RS18450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS18465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_RS18480	COG3130	regulation of translation
CH57_RS18490	COG3009	Protein conserved in bacteria
CH57_RS18495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH57_RS18495	COG3008	intermembrane lipid transfer
CH57_RS18500	COG2995	paraquat-inducible protein a
CH57_RS18505	COG0488	(ABC) transporter
CH57_RS18515	COG0633	Ferredoxin
CH57_RS18515	COG3217	Mosc domain protein beta barrel domain protein
CH57_RS18530	COG0308	aminopeptidase N
CH57_RS18550	COG1448	Aminotransferase
CH57_RS18555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH57_RS18560	COG3108	Peptidase M15
CH57_RS18565	COG2989	Protein conserved in bacteria
CH57_RS18595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH57_RS18605	COG3173	Aminoglycoside phosphotransferase
CH57_RS18620	COG1278	Cold shock
CH57_RS18630	COG5383	Protein conserved in bacteria
CH57_RS18645	COG0658	competence protein
CH57_RS18645	COG2333	competence protein COMEC
CH57_RS18660	COG0539	negative regulation of cytoplasmic translation
CH57_RS18685	COG5295	Hep Hag repeat protein
CH57_RS18685	COG5295	Hep Hag repeat protein
CH57_RS18690	COG0252	asparaginase activity
CH57_RS18695	COG1944	ATP diphosphatase activity
CH57_RS18700	COG2116	formate transmembrane transporter activity
CH57_RS18705	COG1882	Formate acetyltransferase
CH57_RS18715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH57_RS18730	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH57_RS18740	COG3107	peptidoglycan biosynthetic process
CH57_RS18740	COG1674	ftsk spoiiie
CH57_RS18750	COG0492	ferredoxin-NADP+ reductase activity
CH57_RS18765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH57_RS18775	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH57_RS18795	COG1278	Cold shock
CH57_RS18805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH57_RS18815	COG3593	DNA synthesis involved in DNA repair
CH57_RS18820	COG2431	L-lysine efflux transmembrane transporter activity
CH57_RS18830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH57_RS18835	COG0028	Belongs to the TPP enzyme family
CH57_RS18840	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH57_RS18845	COG0702	epimerase
CH57_RS18850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_RS18860	COG1605	Chorismate mutase
CH57_RS18865	COG1126	abc transporter atp-binding protein
CH57_RS18870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS18875	COG4215	(ABC) transporter
CH57_RS18880	COG4160	amino acid transport
CH57_RS18905	COG1120	ATPase activity
CH57_RS18935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS18950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_RS18965	COG1067	ATP-dependent peptidase activity
CH57_RS18995	COG3070	regulator of competence-specific genes
CH57_RS19000	COG1289	transmembrane transporter activity
CH57_RS19005	COG3304	Inner membrane component domain
CH57_RS19010	COG0210	DNA helicase
CH57_RS19025	COG1832	CoA-binding protein
CH57_RS19045	COG2920	part of a sulfur-relay system
CH57_RS19080	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS19090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH57_RS19095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS19105	COG3425	synthase
CH57_RS19115	COG1024	Enoyl-CoA hydratase
CH57_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS19130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH57_RS19135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH57_RS19270	COG0488	(ABC) transporter
CH57_RS19280	COG3328	transposase activity
CH57_RS19290	COG0303	'Molybdopterin
CH57_RS19300	COG1136	(ABC) transporter
CH57_RS19335	COG0583	DNA-binding transcription factor activity
CH57_RS19340	COG0477	Major facilitator Superfamily
CH57_RS19350	COG2311	Membrane
CH57_RS19365	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH57_RS19370	COG2949	membrane
CH57_RS19385	COG1346	cytolysis
CH57_RS19395	COG2814	Major facilitator Superfamily
CH57_RS19440	COG0489	protein tyrosine kinase activity
CH57_RS19455	COG2982	Protein involved in outer membrane biogenesis
CH57_RS19460	COG1253	flavin adenine dinucleotide binding
CH57_RS19465	COG4114	ferric iron reductase
CH57_RS19470	COG0076	glutamate decarboxylase activity
CH57_RS19475	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH57_RS19490	COG1120	ATPase activity
CH57_RS19495	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_RS19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH57_RS19505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH57_RS19520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH57_RS19525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH57_RS19535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH57_RS19535	COG0140	phosphoribosyl-ATP diphosphatase activity
CH57_RS19555	COG0131	Imidazoleglycerol-phosphate dehydratase
CH57_RS19555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH57_RS19565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH57_RS19575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH57_RS19585	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS19590	COG1129	ABC transporter
CH57_RS19595	COG1129	ABC transporter
CH57_RS19600	COG0371	Dehydrogenase
CH57_RS19610	COG0531	amino acid
CH57_RS19615	COG2925	Exonuclease
CH57_RS19635	COG1470	cell adhesion involved in biofilm formation
CH57_RS19635	COG1388	LysM domain
CH57_RS19640	COG2271	Major facilitator Superfamily
CH57_RS19645	COG3011	Protein conserved in bacteria
CH57_RS19650	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS19660	COG4948	Mandelate Racemase Muconate Lactonizing
CH57_RS19675	COG0534	Mate efflux family protein
CH57_RS19695	COG3122	Protein conserved in bacteria
CH57_RS19720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH57_RS19740	COG2223	nitrite transmembrane transporter activity
CH57_RS19745	COG3328	transposase activity
CH57_RS19770	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH57_RS19775	COG3328	transposase activity
CH57_RS19780	COG1530	ribonuclease E activity
CH57_RS19785	COG0564	pseudouridine synthase activity
CH57_RS19800	COG0424	maF-like protein
CH57_RS19805	COG1399	metal-binding, possibly nucleic acid-binding protein
CH57_RS19810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH57_RS19840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH57_RS19850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH57_RS19855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH57_RS19865	COG0470	DNA polymerase III
CH57_RS19870	COG0084	hydrolase, TatD family'
CH57_RS19875	COG1263	PTS System
CH57_RS19875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_RS19885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH57_RS19890	COG0537	adenosine 5'-monophosphoramidase activity
CH57_RS19895	COG5633	Lipoprotein
CH57_RS19910	COG1472	Belongs to the glycosyl hydrolase 3 family
CH57_RS19920	COG1252	NADH dehydrogenase
CH57_RS19935	COG3328	transposase activity
CH57_RS19960	COG3134	Outer membrane lipoprotein
CH57_RS19965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH57_RS19970	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH57_RS19980	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH57_RS19985	COG1940	carbohydrate kinase activity
CH57_RS20000	COG2850	peptidyl-arginine hydroxylation
CH57_RS20010	COG0745	RESPONSE REGULATOR receiver
CH57_RS20020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH57_RS20040	COG1187	pseudouridine synthase activity
CH57_RS20045	COG0538	isocitrate dehydrogenase activity
CH57_RS20060	COG0840	transmembrane signaling receptor activity
CH57_RS20065	COG0702	epimerase
CH57_RS20070	COG1733	regulation of RNA biosynthetic process
CH57_RS20095	COG1522	sequence-specific DNA binding
CH57_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS20105	COG3321	synthase
CH57_RS20105	COG0604	alcohol dehydrogenase
CH57_RS20135	COG1285	pathogenesis
CH57_RS20160	COG1360	Flagellar Motor Protein
CH57_RS20165	COG2198	Histidine kinase
CH57_RS20165	COG0643	Histidine kinase
CH57_RS20170	COG0835	chemotaxis
CH57_RS20175	COG2271	Major facilitator Superfamily
CH57_RS20180	COG0251	oxidation-reduction process
CH57_RS20190	COG2964	Protein conserved in bacteria
CH57_RS20210	COG0840	transmembrane signaling receptor activity
CH57_RS20215	COG0840	transmembrane signaling receptor activity
CH57_RS20220	COG0840	transmembrane signaling receptor activity
CH57_RS20225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH57_RS20235	COG0745	RESPONSE REGULATOR receiver
CH57_RS20240	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH57_RS20250	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH57_RS20260	COG5295	Hep Hag repeat protein
CH57_RS20275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH57_RS20330	COG3121	Chaperone
CH57_RS20350	COG3008	intermembrane lipid transfer
CH57_RS20355	COG2995	paraquat-inducible protein a
CH57_RS20360	COG1956	GAF domain-containing protein
CH57_RS20370	COG0793	Belongs to the peptidase S41A family
CH57_RS20380	COG3539	Fimbrial protein
CH57_RS20385	COG3121	Chaperone
CH57_RS20400	COG3121	Chaperone
CH57_RS20405	COG2814	Major facilitator Superfamily
CH57_RS20410	COG0823	Involved in the tonB-independent uptake of proteins
CH57_RS20420	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH57_RS20425	COG1823	symporter activity
CH57_RS20430	COG1988	membrane-bound metal-dependent
CH57_RS20435	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH57_RS20440	COG1653	transport
CH57_RS20445	COG3842	ATPase activity
CH57_RS20450	COG0395	ABC-type sugar transport system, permease component
CH57_RS20455	COG1175	transmembrane transport
CH57_RS20465	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS20475	COG1917	Cupin 2, conserved barrel domain protein
CH57_RS20480	COG3328	transposase activity
CH57_RS20530	COG1132	(ABC) transporter
CH57_RS20540	COG2207	Transcriptional regulator
CH57_RS20575	COG1113	amino acid transport
CH57_RS20600	COG1496	oxidoreductase activity
CH57_RS20605	COG2226	methyltransferase
CH57_RS20615	COG5002	protein histidine kinase activity
CH57_RS20615	COG3447	MASE1 domain protein
CH57_RS20615	COG5001	Diguanylate cyclase
CH57_RS20635	COG3716	PTS system mannose fructose sorbose family IID component
CH57_RS20640	COG3715	PTS system
CH57_RS20645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH57_RS20645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH57_RS20650	COG1253	flavin adenine dinucleotide binding
CH57_RS20655	COG1846	Transcriptional regulator
CH57_RS20670	COG1012	belongs to the aldehyde dehydrogenase family
CH57_RS20675	COG3384	dioxygenase
CH57_RS20685	COG3971	2-oxopent-4-enoate hydratase activity
CH57_RS20700	COG2368	4-hydroxyphenylacetate
CH57_RS20705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH57_RS20710	COG1760	l-serine dehydratase
CH57_RS20735	COG0513	Belongs to the DEAD box helicase family
CH57_RS20740	COG3141	response to X-ray
CH57_RS20755	COG1770	oligopeptidase
CH57_RS20770	COG1528	Iron-storage protein
CH57_RS20775	COG2372	response to copper ion
CH57_RS20805	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH57_RS20810	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH57_RS20835	COG3418	PFAM FlgN family protein
CH57_RS20840	COG2747	anti-sigma28 factor FlgM
CH57_RS20850	COG1815	bacterial-type flagellum-dependent cell motility
CH57_RS20855	COG1558	bacterial-type flagellum-dependent cell motility
CH57_RS20895	COG1256	bacterial-type flagellum assembly
CH57_RS20905	COG2390	Transcriptional regulator
CH57_RS20910	COG3347	Dehydrogenase
CH57_RS20910	COG1028	Short-chain dehydrogenase reductase Sdr
CH57_RS20915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS20925	COG1129	ABC transporter
CH57_RS20930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH57_RS20935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH57_RS20955	COG1987	bacterial-type flagellum assembly
CH57_RS20980	COG1580	Controls the rotational direction of flagella during chemotaxis
CH57_RS20995	COG1157	protein secretion by the type III secretion system
CH57_RS21015	COG1677	Flagellar hook-basal body complex protein FliE
CH57_RS21030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH57_RS21035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH57_RS21040	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH57_RS21075	COG1191	sigma factor activity
CH57_RS21090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH57_RS21095	COG0765	amino acid transport
CH57_RS21100	COG1126	abc transporter atp-binding protein
CH57_RS21115	COG0506	proline dehydrogenase activity
CH57_RS21115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH57_RS21115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH57_RS21130	COG0672	)-iron permease
CH57_RS21135	COG2822	iron ion transport
CH57_RS21155	COG1113	amino acid transport
CH57_RS21175	COG3136	membrane protein required for alginate biosynthesis
CH57_RS21185	COG2197	response regulator
CH57_RS21330	COG2188	Transcriptional regulator
CH57_RS21340	COG0673	inositol 2-dehydrogenase activity
CH57_RS21350	COG1175	transmembrane transport
CH57_RS21590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)