locus-tag	class	description
YPA_RS00005	COG0716	FMN binding
YPA_RS00010	COG1522	sequence-specific DNA binding
YPA_RS00050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPA_RS00060	COG0477	Major facilitator Superfamily
YPA_RS00065	COG2186	Transcriptional regulator
YPA_RS00110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPA_RS00115	COG2224	Isocitrate lyase
YPA_RS00125	COG1414	Transcriptional regulator
YPA_RS00130	COG1414	Transcriptional regulator
YPA_RS00150	COG0527	aspartate kinase activity
YPA_RS00165	COG3833	ABC-type maltose transport systems, permease component
YPA_RS00170	COG1175	transmembrane transport
YPA_RS00230	COG2801	Transposase and inactivated derivatives
YPA_RS00260	COG0195	Participates in both transcription termination and antitermination
YPA_RS00280	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPA_RS00290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPA_RS00305	COG1534	Rna-binding protein
YPA_RS00315	COG2027	D-alanyl-D-alanine carboxypeptidase
YPA_RS00320	COG0745	RESPONSE REGULATOR receiver
YPA_RS00325	COG0642	Histidine kinase
YPA_RS00335	COG0697	spore germination
YPA_RS00350	COG0142	geranyltranstransferase activity
YPA_RS00360	COG3423	Transcriptional regulator
YPA_RS00385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPA_RS00390	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YPA_RS00395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPA_RS00400	COG2105	PFAM AIG2 family protein
YPA_RS00405	COG2911	Protein conserved in bacteria
YPA_RS00410	COG0729	surface antigen
YPA_RS00420	COG1253	flavin adenine dinucleotide binding
YPA_RS00430	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPA_RS00440	COG0737	Belongs to the 5'-nucleotidase family
YPA_RS00450	COG0545	Peptidyl-prolyl cis-trans isomerase
YPA_RS00455	COG3061	Opacity-associated protein A
YPA_RS00480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPA_RS00490	COG0360	Binds together with S18 to 16S ribosomal RNA
YPA_RS00500	COG1073	alpha beta
YPA_RS00525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPA_RS00545	COG1629	transport
YPA_RS00570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPA_RS00575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPA_RS00575	COG0678	peroxiredoxin activity
YPA_RS00655	COG1879	ABC-type sugar transport system periplasmic component
YPA_RS00660	COG1129	ABC transporter
YPA_RS00665	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS00670	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS00680	COG3085	chromosome segregation
YPA_RS00695	COG3978	acetolactate synthase activity
YPA_RS00700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPA_RS00740	COG0583	DNA-binding transcription factor activity
YPA_RS00780	COG3121	Chaperone
YPA_RS00795	COG3121	Chaperone
YPA_RS00810	COG3328	transposase activity
YPA_RS00820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPA_RS00850	COG3118	belongs to the thioredoxin family
YPA_RS00855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPA_RS00860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPA_RS00865	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPA_RS00870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPA_RS00875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPA_RS00880	COG1088	dTDP-glucose 4,6-dehydratase activity
YPA_RS00885	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPA_RS00890	COG0456	acetyltransferase
YPA_RS00895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPA_RS00900	COG2244	polysaccharide biosynthetic process
YPA_RS00920	COG1113	amino acid transport
YPA_RS00960	COG3071	HemY protein
YPA_RS00965	COG2959	enzyme of heme biosynthesis
YPA_RS00970	COG1587	Uroporphyrinogen-III synthase
YPA_RS00985	COG3072	Adenylate cyclase
YPA_RS01005	COG3159	Protein conserved in bacteria
YPA_RS01010	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPA_RS01015	COG1011	Hydrolase
YPA_RS01020	COG0210	DNA helicase
YPA_RS01030	COG5441	Belongs to the UPF0261 family
YPA_RS01035	COG5564	TIM-barrel signal transduction protein
YPA_RS01050	COG2050	protein possibly involved in aromatic compounds catabolism
YPA_RS01055	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPA_RS01060	COG0514	ATP-dependent DNA helicase (RecQ)
YPA_RS01065	COG1280	lysine exporter protein (LysE YggA)
YPA_RS01070	COG1280	lysine exporter protein (LysE YggA)
YPA_RS01075	COG2267	carboxylic ester hydrolase activity
YPA_RS01080	COG0561	phosphatase activity
YPA_RS01090	COG0584	glycerophosphoryl diester phosphodiesterase
YPA_RS01100	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPA_RS01110	COG0247	lactate metabolic process
YPA_RS01120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPA_RS01150	COG3776	membrane
YPA_RS01155	COG0742	ribosomal rna small subunit methyltransferase
YPA_RS01165	COG0552	protein localization to endoplasmic reticulum
YPA_RS01165	COG0552	protein localization to endoplasmic reticulum
YPA_RS01170	COG2884	Cell division ATP-binding protein ftsE
YPA_RS01175	COG2177	Part of the ABC transporter FtsEX involved in
YPA_RS01200	COG0683	leucine binding
YPA_RS01220	COG4177	L-phenylalanine transmembrane transporter activity
YPA_RS01230	COG0410	ABC transporter
YPA_RS01290	COG0584	glycerophosphoryl diester phosphodiesterase
YPA_RS01295	COG0679	Auxin Efflux Carrier
YPA_RS01300	COG0697	spore germination
YPA_RS01305	COG0583	DNA-binding transcription factor activity
YPA_RS01315	COG0412	Dienelactone hydrolase
YPA_RS01330	COG1966	Carbon starvation protein
YPA_RS01335	COG0586	Pfam SNARE associated Golgi protein
YPA_RS01340	COG1322	Protein conserved in bacteria
YPA_RS01360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPA_RS01370	COG0805	protein transport
YPA_RS01400	COG1575	Belongs to the MenA family. Type 1 subfamily
YPA_RS01415	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPA_RS01420	COG1609	Transcriptional regulator
YPA_RS01430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPA_RS01440	COG4682	membrane
YPA_RS01460	COG0460	homoserine dehydrogenase
YPA_RS01460	COG0527	aspartate kinase activity
YPA_RS01470	COG2801	Transposase and inactivated derivatives
YPA_RS01480	COG2211	Major facilitator Superfamily
YPA_RS01530	COG2771	luxR family
YPA_RS01535	COG3916	Acyl-homoserine-lactone synthase
YPA_RS01670	COG1982	Orn Lys Arg decarboxylase major
YPA_RS01675	COG1879	ABC-type sugar transport system periplasmic component
YPA_RS01680	COG1129	ABC transporter
YPA_RS01685	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS01690	COG4774	siderophore transport
YPA_RS01710	COG1194	a g-specific adenine glycosylase
YPA_RS01720	COG3171	Protein conserved in bacteria
YPA_RS01740	COG3064	Membrane
YPA_RS01740	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPA_RS01740	COG1073	alpha beta
YPA_RS01745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPA_RS01750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPA_RS01760	COG0762	integral membrane protein
YPA_RS01765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPA_RS01770	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPA_RS01775	COG2805	Type II/IV secretion system protein
YPA_RS01785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPA_RS01800	COG0189	ligase activity
YPA_RS01805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPA_RS01810	COG2356	endonuclease I
YPA_RS01825	COG1166	arginine decarboxylase activity
YPA_RS01840	COG0501	Belongs to the peptidase M48B family
YPA_RS01845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPA_RS01870	COG0191	fructose-bisphosphate aldolase activity
YPA_RS01920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPA_RS01925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPA_RS01940	COG0006	proline dipeptidase activity
YPA_RS01945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPA_RS01950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPA_RS01980	COG5295	Hep Hag repeat protein
YPA_RS01990	COG1272	protein, Hemolysin III
YPA_RS02015	COG0745	RESPONSE REGULATOR receiver
YPA_RS02020	COG2205	protein histidine kinase activity
YPA_RS02025	COG4452	Inner membrane protein CreD
YPA_RS02030	COG0716	FMN binding
YPA_RS02035	COG4974	Belongs to the 'phage' integrase family
YPA_RS02040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPA_RS02045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPA_RS02065	COG0582	viral genome integration into host DNA
YPA_RS02080	COG0582	viral genome integration into host DNA
YPA_RS02110	COG2944	sequence-specific DNA binding
YPA_RS02205	COG1695	Transcriptional regulator
YPA_RS02210	COG0791	NLP P60 protein
YPA_RS02220	COG1879	ABC-type sugar transport system periplasmic component
YPA_RS02225	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS02230	COG1129	ABC transporter
YPA_RS02240	COG2182	Extracellular solute-binding protein
YPA_RS02245	COG1175	transmembrane transport
YPA_RS02250	COG3833	ABC-type maltose transport systems, permease component
YPA_RS02255	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPA_RS02260	COG1874	Beta-galactosidase
YPA_RS02265	COG1263	PTS System
YPA_RS02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPA_RS02285	COG2271	Major facilitator Superfamily
YPA_RS02315	COG3119	arylsulfatase activity
YPA_RS02320	COG0641	radical SAM
YPA_RS02330	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS02340	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS02345	COG3716	PTS system mannose fructose sorbose family IID component
YPA_RS02350	COG3715	PTS system
YPA_RS02355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPA_RS02360	COG2222	sugar isomerase
YPA_RS02370	COG1349	DNA-binding transcription factor activity
YPA_RS02375	COG3119	arylsulfatase activity
YPA_RS02420	COG0288	reversible hydration of carbon dioxide
YPA_RS02440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPA_RS02510	COG0840	transmembrane signaling receptor activity
YPA_RS02525	COG0583	DNA-binding transcription factor activity
YPA_RS02530	COG2814	Major facilitator Superfamily
YPA_RS02535	COG0583	DNA-binding transcription factor activity
YPA_RS02545	COG1609	Transcriptional regulator
YPA_RS02575	COG0667	Aldo Keto reductase
YPA_RS02640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPA_RS02650	COG1074	ATP-dependent DNA helicase activity
YPA_RS02655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPA_RS02665	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPA_RS02680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPA_RS02685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPA_RS02690	COG2166	iron-sulfur cluster assembly
YPA_RS02695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPA_RS02700	COG0583	DNA-binding transcription factor activity
YPA_RS02705	COG2363	Small membrane protein
YPA_RS02735	COG1611	Belongs to the LOG family
YPA_RS02760	COG3098	single-species biofilm formation
YPA_RS02765	COG0564	pseudouridine synthase activity
YPA_RS02835	COG0575	Belongs to the CDS family
YPA_RS02840	COG0750	zinc metalloprotease
YPA_RS02855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPA_RS02880	COG0587	DNA-directed DNA polymerase activity
YPA_RS02890	COG0346	lactoylglutathione lyase activity
YPA_RS02895	COG0037	tRNA processing
YPA_RS02905	COG4568	rho-dependent transcription termination
YPA_RS02915	COG4681	YaeQ
YPA_RS02925	COG3015	lipoprotein NlpE involved in copper resistance
YPA_RS02935	COG1720	tRNA m6t6A37 methyltransferase activity
YPA_RS02945	COG1464	Belongs to the NlpA lipoprotein family
YPA_RS02950	COG2011	ABC-type metal ion transport system permease component
YPA_RS02960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPA_RS02990	COG0656	L-ascorbic acid biosynthetic process
YPA_RS03005	COG1388	LysM domain
YPA_RS03005	COG0741	lytic transglycosylase activity
YPA_RS03010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPA_RS03015	COG2226	methyltransferase
YPA_RS03035	COG1953	Uracil, thiamine, allantoin
YPA_RS03065	COG3657	addiction module killer protein
YPA_RS03125	COG0582	viral genome integration into host DNA
YPA_RS03145	COG2867	negative regulation of translational initiation
YPA_RS03155	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPA_RS03160	COG0497	DNA recombination
YPA_RS03165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPA_RS03180	COG2009	succinate dehydrogenase
YPA_RS03185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPA_RS03190	COG1053	succinate dehydrogenase
YPA_RS03200	COG0567	Dehydrogenase, E1 component
YPA_RS03205	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPA_RS03215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPA_RS03220	COG1271	oxidase subunit
YPA_RS03225	COG1294	oxidase, subunit
YPA_RS03230	COG4890	Cyd operon protein YbgT
YPA_RS03235	COG3790	cyd operon protein YbgE
YPA_RS03240	COG0824	Thioesterase
YPA_RS03245	COG0811	peptide transport
YPA_RS03250	COG0848	biopolymer transport protein
YPA_RS03255	COG3064	Membrane
YPA_RS03255	COG3064	Membrane
YPA_RS03265	COG2885	chlorophyll binding
YPA_RS03270	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPA_RS03300	COG1230	cation diffusion facilitator family transporter
YPA_RS03305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPA_RS03320	COG1686	Belongs to the peptidase S11 family
YPA_RS03330	COG0814	amino acid
YPA_RS03335	COG1349	DNA-binding transcription factor activity
YPA_RS03345	COG0671	phosphoesterase, PA-phosphatase related
YPA_RS03380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPA_RS03385	COG3842	ATPase activity
YPA_RS03390	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPA_RS03395	COG1177	transmembrane transport
YPA_RS03410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS03440	COG1120	ATPase activity
YPA_RS03465	COG4160	amino acid transport
YPA_RS03470	COG4215	(ABC) transporter
YPA_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS03480	COG1126	abc transporter atp-binding protein
YPA_RS03485	COG1605	Chorismate mutase
YPA_RS03495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPA_RS03500	COG0702	epimerase
YPA_RS03505	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPA_RS03510	COG0028	Belongs to the TPP enzyme family
YPA_RS03515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPA_RS03525	COG2431	L-lysine efflux transmembrane transporter activity
YPA_RS03530	COG3593	DNA synthesis involved in DNA repair
YPA_RS03535	COG2990	Protein conserved in bacteria
YPA_RS03540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPA_RS03550	COG1278	Cold shock
YPA_RS03560	COG0542	response to heat
YPA_RS03570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPA_RS03580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPA_RS03595	COG0492	ferredoxin-NADP+ reductase activity
YPA_RS03605	COG3107	peptidoglycan biosynthetic process
YPA_RS03605	COG1674	ftsk spoiiie
YPA_RS03615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPA_RS03630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPA_RS03640	COG1882	Formate acetyltransferase
YPA_RS03645	COG2116	formate transmembrane transporter activity
YPA_RS03650	COG1944	ATP diphosphatase activity
YPA_RS03655	COG0252	asparaginase activity
YPA_RS03660	COG5295	Hep Hag repeat protein
YPA_RS03660	COG5295	Hep Hag repeat protein
YPA_RS03685	COG0539	negative regulation of cytoplasmic translation
YPA_RS03700	COG2333	competence protein COMEC
YPA_RS03700	COG0658	competence protein
YPA_RS03730	COG5383	Protein conserved in bacteria
YPA_RS03735	COG1278	Cold shock
YPA_RS03755	COG3173	Aminoglycoside phosphotransferase
YPA_RS03765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPA_RS03795	COG2989	Protein conserved in bacteria
YPA_RS03800	COG3108	Peptidase M15
YPA_RS03805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPA_RS03810	COG1448	Aminotransferase
YPA_RS03830	COG0308	aminopeptidase N
YPA_RS03845	COG0633	Ferredoxin
YPA_RS03845	COG3217	Mosc domain protein beta barrel domain protein
YPA_RS03855	COG0488	(ABC) transporter
YPA_RS03860	COG2995	paraquat-inducible protein a
YPA_RS03865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPA_RS03865	COG3008	intermembrane lipid transfer
YPA_RS03870	COG3009	Protein conserved in bacteria
YPA_RS03880	COG3130	regulation of translation
YPA_RS03895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPA_RS03910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPA_RS03925	COG1067	ATP-dependent peptidase activity
YPA_RS03955	COG3070	regulator of competence-specific genes
YPA_RS03960	COG1289	transmembrane transporter activity
YPA_RS03965	COG3304	Inner membrane component domain
YPA_RS03970	COG0210	DNA helicase
YPA_RS03985	COG1832	CoA-binding protein
YPA_RS04005	COG2920	part of a sulfur-relay system
YPA_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS04050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPA_RS04055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPA_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS04065	COG3425	synthase
YPA_RS04075	COG1024	Enoyl-CoA hydratase
YPA_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS04090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPA_RS04095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPA_RS04240	COG0488	(ABC) transporter
YPA_RS04250	COG3328	transposase activity
YPA_RS04260	COG0303	'Molybdopterin
YPA_RS04270	COG1136	(ABC) transporter
YPA_RS04305	COG0583	DNA-binding transcription factor activity
YPA_RS04310	COG0477	Major facilitator Superfamily
YPA_RS04320	COG2311	Membrane
YPA_RS04335	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPA_RS04340	COG2949	membrane
YPA_RS04355	COG1346	cytolysis
YPA_RS04365	COG2814	Major facilitator Superfamily
YPA_RS04400	COG0489	protein tyrosine kinase activity
YPA_RS04415	COG2982	Protein involved in outer membrane biogenesis
YPA_RS04420	COG1253	flavin adenine dinucleotide binding
YPA_RS04425	COG4114	ferric iron reductase
YPA_RS04430	COG0076	glutamate decarboxylase activity
YPA_RS04435	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPA_RS04450	COG1120	ATPase activity
YPA_RS04455	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPA_RS04460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPA_RS04465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPA_RS04480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPA_RS04485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPA_RS04495	COG0140	phosphoribosyl-ATP diphosphatase activity
YPA_RS04495	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPA_RS04515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPA_RS04515	COG0131	Imidazoleglycerol-phosphate dehydratase
YPA_RS04525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPA_RS04535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPA_RS04545	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS04550	COG1129	ABC transporter
YPA_RS04555	COG1129	ABC transporter
YPA_RS04560	COG0371	Dehydrogenase
YPA_RS04570	COG0531	amino acid
YPA_RS04575	COG2925	Exonuclease
YPA_RS04590	COG3328	transposase activity
YPA_RS04595	COG1388	LysM domain
YPA_RS04595	COG1470	cell adhesion involved in biofilm formation
YPA_RS04600	COG2271	Major facilitator Superfamily
YPA_RS04605	COG3011	Protein conserved in bacteria
YPA_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS04620	COG4948	Mandelate Racemase Muconate Lactonizing
YPA_RS04635	COG0534	Mate efflux family protein
YPA_RS04655	COG3122	Protein conserved in bacteria
YPA_RS04680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPA_RS04700	COG2223	nitrite transmembrane transporter activity
YPA_RS04705	COG3328	transposase activity
YPA_RS04715	COG0513	Belongs to the DEAD box helicase family
YPA_RS04735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPA_RS04745	COG1686	Belongs to the peptidase S11 family
YPA_RS04750	COG0277	FAD linked oxidase domain protein
YPA_RS04770	COG2261	transglycosylase associated protein
YPA_RS04780	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPA_RS04795	COG4807	Protein conserved in bacteria
YPA_RS04815	COG1122	ATPase activity
YPA_RS04835	COG2897	thiosulfate sulfurtransferase activity
YPA_RS04840	COG1732	Glycine betaine
YPA_RS04845	COG1732	Glycine betaine
YPA_RS04850	COG1174	glycine betaine transport
YPA_RS04855	COG1125	glycine betaine transport
YPA_RS04860	COG1174	glycine betaine transport
YPA_RS04865	COG0531	amino acid
YPA_RS04870	COG1982	Orn Lys Arg decarboxylase major
YPA_RS04880	COG0697	spore germination
YPA_RS04915	COG0814	amino acid
YPA_RS04930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPA_RS04960	COG0784	Response regulator, receiver
YPA_RS04960	COG2205	protein histidine kinase activity
YPA_RS04970	COG2198	Histidine kinase
YPA_RS04970	COG0642	Histidine kinase
YPA_RS04975	COG2198	Histidine kinase
YPA_RS04975	COG0642	Histidine kinase
YPA_RS04980	COG2223	nitrite transmembrane transporter activity
YPA_RS05010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPA_RS05055	COG3395	kinase activity
YPA_RS05065	COG1349	DNA-binding transcription factor activity
YPA_RS05070	COG3622	Belongs to the hyi family
YPA_RS05090	COG4386	tail sheath protein
YPA_RS05130	COG3299	homolog of phage Mu protein gp47
YPA_RS05150	COG1737	Transcriptional regulator
YPA_RS05155	COG2723	6-phospho-beta-galactosidase activity
YPA_RS05175	COG3157	Type VI secretion system effector, Hcp
YPA_RS05190	COG3157	Type VI secretion system effector, Hcp
YPA_RS05200	COG3083	sulfuric ester hydrolase activity
YPA_RS05205	COG3082	Protein of unknown function (DUF1414)
YPA_RS05230	COG1061	Type III restriction enzyme res subunit
YPA_RS05235	COG1187	pseudouridine synthase activity
YPA_RS05240	COG2814	Major facilitator Superfamily
YPA_RS05250	COG4172	Belongs to the ABC transporter superfamily
YPA_RS05255	COG4239	(ABC) transporter, permease
YPA_RS05260	COG4174	ABC transporter (Permease)
YPA_RS05265	COG4166	transmembrane transport
YPA_RS05270	COG2200	EAL domain
YPA_RS05275	COG0791	NLP P60 protein
YPA_RS05280	COG0671	phosphoesterase, PA-phosphatase related
YPA_RS05285	COG0523	cobalamin synthesis protein
YPA_RS05295	COG2186	Transcriptional regulator
YPA_RS05300	COG0246	Mannitol dehydrogenase
YPA_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS05340	COG2801	Transposase and inactivated derivatives
YPA_RS05370	COG1129	ABC transporter
YPA_RS05380	COG0494	nUDIX hydrolase
YPA_RS05390	COG1105	Belongs to the carbohydrate kinase PfkB family
YPA_RS05395	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPA_RS05395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPA_RS05395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPA_RS05400	COG3710	Transcriptional regulator
YPA_RS05415	COG3121	Chaperone
YPA_RS05420	COG3188	usher protein
YPA_RS05430	COG2855	membrane
YPA_RS05435	COG0583	DNA-binding transcription factor activity
YPA_RS05440	COG0833	amino acid
YPA_RS05450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPA_RS05460	COG4771	TonB-dependent receptor
YPA_RS05465	COG0625	glutathione transferase activity
YPA_RS05490	COG2011	ABC-type metal ion transport system permease component
YPA_RS05495	COG1686	Belongs to the peptidase S11 family
YPA_RS05510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPA_RS05525	COG2017	converts alpha-aldose to the beta-anomer
YPA_RS05540	COG1085	galactose-1-phosphate uridylyltransferase
YPA_RS05545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPA_RS05560	COG1119	ATPase activity
YPA_RS05565	COG3585	molybdate ion transport
YPA_RS05565	COG2005	Transcriptional regulator
YPA_RS05575	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPA_RS05580	COG4149	molybdate abc transporter
YPA_RS05590	COG0561	phosphatase activity
YPA_RS05615	COG2226	methyltransferase
YPA_RS05625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YPA_RS05635	COG4628	conserved protein (DUF2132)
YPA_RS05640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPA_RS05650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPA_RS05660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPA_RS05665	COG0314	molybdopterin synthase activity
YPA_RS05700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPA_RS05705	COG0583	DNA-binding transcription factor activity
YPA_RS05715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPA_RS05720	COG2211	Major facilitator Superfamily
YPA_RS05730	COG2211	Major facilitator Superfamily
YPA_RS05750	COG1902	pentaerythritol trinitrate reductase activity
YPA_RS05770	COG0842	Transport permease protein
YPA_RS05775	COG0842	Transport permease protein
YPA_RS05780	COG1131	(ABC) transporter
YPA_RS05790	COG1309	transcriptional regulator
YPA_RS05795	COG0513	Belongs to the DEAD box helicase family
YPA_RS05830	COG3328	transposase activity
YPA_RS05880	COG1132	(ABC) transporter
YPA_RS05890	COG2207	Transcriptional regulator
YPA_RS05925	COG1113	amino acid transport
YPA_RS05950	COG1496	oxidoreductase activity
YPA_RS05955	COG2226	methyltransferase
YPA_RS05965	COG5001	Diguanylate cyclase
YPA_RS05965	COG5002	protein histidine kinase activity
YPA_RS05965	COG3447	MASE1 domain protein
YPA_RS05985	COG3716	PTS system mannose fructose sorbose family IID component
YPA_RS05990	COG3715	PTS system
YPA_RS05995	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPA_RS05995	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS06000	COG1253	flavin adenine dinucleotide binding
YPA_RS06005	COG1846	Transcriptional regulator
YPA_RS06020	COG1012	belongs to the aldehyde dehydrogenase family
YPA_RS06025	COG3384	dioxygenase
YPA_RS06035	COG3971	2-oxopent-4-enoate hydratase activity
YPA_RS06050	COG2368	4-hydroxyphenylacetate
YPA_RS06060	COG1760	l-serine dehydratase
YPA_RS06085	COG0513	Belongs to the DEAD box helicase family
YPA_RS06090	COG3141	response to X-ray
YPA_RS06105	COG1770	oligopeptidase
YPA_RS06130	COG1528	Iron-storage protein
YPA_RS06135	COG2372	response to copper ion
YPA_RS06165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPA_RS06195	COG3418	PFAM FlgN family protein
YPA_RS06200	COG2747	anti-sigma28 factor FlgM
YPA_RS06210	COG1815	bacterial-type flagellum-dependent cell motility
YPA_RS06215	COG1558	bacterial-type flagellum-dependent cell motility
YPA_RS06255	COG1256	bacterial-type flagellum assembly
YPA_RS06265	COG2390	Transcriptional regulator
YPA_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS06270	COG3347	Dehydrogenase
YPA_RS06275	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS06285	COG1129	ABC transporter
YPA_RS06290	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS06295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPA_RS06315	COG1987	bacterial-type flagellum assembly
YPA_RS06340	COG1580	Controls the rotational direction of flagella during chemotaxis
YPA_RS06355	COG1157	protein secretion by the type III secretion system
YPA_RS06375	COG1677	Flagellar hook-basal body complex protein FliE
YPA_RS06390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPA_RS06395	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPA_RS06400	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YPA_RS06435	COG1191	sigma factor activity
YPA_RS06450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS06455	COG0765	amino acid transport
YPA_RS06460	COG1126	abc transporter atp-binding protein
YPA_RS06485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPA_RS06485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPA_RS06485	COG0506	proline dehydrogenase activity
YPA_RS06500	COG0672	)-iron permease
YPA_RS06505	COG2822	iron ion transport
YPA_RS06525	COG1113	amino acid transport
YPA_RS06550	COG3136	membrane protein required for alginate biosynthesis
YPA_RS06560	COG2197	response regulator
YPA_RS06700	COG2188	Transcriptional regulator
YPA_RS06710	COG0673	inositol 2-dehydrogenase activity
YPA_RS06720	COG1175	transmembrane transport
YPA_RS06725	COG0395	ABC-type sugar transport system, permease component
YPA_RS06730	COG3842	ATPase activity
YPA_RS06800	COG4771	TonB-dependent receptor
YPA_RS06805	COG1021	2,3-dihydroxybenzoate-AMP ligase
YPA_RS06825	COG2226	methyltransferase
YPA_RS06825	COG3433	isochorismatase activity
YPA_RS06825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPA_RS06840	COG1132	(ABC) transporter
YPA_RS06845	COG2814	Major facilitator Superfamily
YPA_RS06850	COG1169	isochorismate synthase
YPA_RS06855	COG0582	viral genome integration into host DNA
YPA_RS06865	COG3121	Chaperone
YPA_RS06875	COG3188	usher protein
YPA_RS06890	COG2205	protein histidine kinase activity
YPA_RS06890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS06900	COG0427	acetyl-CoA hydrolase
YPA_RS06905	COG2030	dehydratase
YPA_RS06930	COG2814	Major facilitator Superfamily
YPA_RS06950	COG2814	Major facilitator Superfamily
YPA_RS06965	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPA_RS06970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPA_RS06980	COG1349	DNA-binding transcription factor activity
YPA_RS06985	COG2066	Belongs to the glutaminase family
YPA_RS06995	COG0672	)-iron permease
YPA_RS07010	COG1136	(ABC) transporter
YPA_RS07010	COG0577	efflux transmembrane transporter activity
YPA_RS07020	COG1136	(ABC) transporter
YPA_RS07020	COG0577	efflux transmembrane transporter activity
YPA_RS07040	COG0006	proline dipeptidase activity
YPA_RS07045	COG0457	Tetratricopeptide repeat
YPA_RS07050	COG1649	PFAM Uncharacterised BCR, COG1649
YPA_RS07050	COG0726	polysaccharide deacetylase
YPA_RS07055	COG1215	transferase activity, transferring glycosyl groups
YPA_RS07060	COG3658	cytochrome
YPA_RS07075	COG1702	phosphate starvation-inducible protein PhoH
YPA_RS07080	COG0387	Pfam Sodium calcium exchanger
YPA_RS07085	COG3850	Histidine kinase
YPA_RS07090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPA_RS07155	COG0402	S-adenosylhomocysteine deaminase activity
YPA_RS07170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPA_RS07175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPA_RS07180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPA_RS07225	COG3328	transposase activity
YPA_RS07250	COG0500	methyltransferase
YPA_RS07290	COG5002	protein histidine kinase activity
YPA_RS07345	COG0012	GTP binding
YPA_RS07365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPA_RS07395	COG2890	protein-(glutamine-N5) methyltransferase activity
YPA_RS07415	COG0659	secondary active sulfate transmembrane transporter activity
YPA_RS07430	COG0659	secondary active sulfate transmembrane transporter activity
YPA_RS07455	COG3833	ABC-type maltose transport systems, permease component
YPA_RS07460	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPA_RS07475	COG3842	ATPase activity
YPA_RS07480	COG0584	glycerophosphoryl diester phosphodiesterase
YPA_RS07485	COG1940	carbohydrate kinase activity
YPA_RS07500	COG3381	protein complex oligomerization
YPA_RS07515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPA_RS07520	COG0673	inositol 2-dehydrogenase activity
YPA_RS07525	COG0728	peptidoglycan biosynthetic process
YPA_RS07545	COG3102	Protein conserved in bacteria
YPA_RS07565	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPA_RS07570	COG1801	Protein of unknown function DUF72
YPA_RS07580	COG0494	nUDIX hydrolase
YPA_RS07610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPA_RS07620	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPA_RS07625	COG0739	heme binding
YPA_RS07630	COG1560	Kdo2-lipid A biosynthetic process
YPA_RS07635	COG0469	pyruvate kinase activity
YPA_RS07640	COG1737	Transcriptional regulator
YPA_RS07645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPA_RS07655	COG0800	Aldolase
YPA_RS07670	COG0251	oxidation-reduction process
YPA_RS07675	COG1199	ATP-dependent helicase activity
YPA_RS07685	COG3065	identical protein binding
YPA_RS07690	COG0318	PFAM AMP-dependent synthetase and ligase
YPA_RS07695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPA_RS07700	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPA_RS07705	COG2894	cell division
YPA_RS07720	COG2951	lytic endotransglycosylase activity
YPA_RS07725	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPA_RS07735	COG0582	viral genome integration into host DNA
YPA_RS07905	COG3328	transposase activity
YPA_RS07915	COG1104	cysteine desulfurase activity
YPA_RS07945	COG2719	SpoVR family
YPA_RS07955	COG2814	Major facilitator Superfamily
YPA_RS07965	COG0583	DNA-binding transcription factor activity
YPA_RS07980	COG2766	serine protein kinase
YPA_RS07985	COG3713	MltA-interacting MipA family protein
YPA_RS08005	COG3139	Protein of unknown function (DUF1315)
YPA_RS08010	COG1335	isochorismatase
YPA_RS08015	COG0252	asparaginase activity
YPA_RS08020	COG0616	signal peptide processing
YPA_RS08025	COG0778	Nitroreductase
YPA_RS08030	COG0709	Synthesizes selenophosphate from selenide and ATP
YPA_RS08035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPA_RS08045	COG0494	nUDIX hydrolase
YPA_RS08050	COG0708	Exodeoxyribonuclease III
YPA_RS08055	COG0583	DNA-binding transcription factor activity
YPA_RS08065	COG3328	transposase activity
YPA_RS08070	COG0788	formyltetrahydrofolate deformylase activity
YPA_RS08080	COG0745	RESPONSE REGULATOR receiver
YPA_RS08110	COG1454	alcohol dehydrogenase
YPA_RS08110	COG1012	belongs to the aldehyde dehydrogenase family
YPA_RS08115	COG2095	MarC family integral membrane protein
YPA_RS08125	COG0601	transmembrane transport
YPA_RS08130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPA_RS08135	COG0444	Belongs to the ABC transporter superfamily
YPA_RS08140	COG4608	Belongs to the ABC transporter superfamily
YPA_RS08175	COG2350	Protein conserved in bacteria
YPA_RS08180	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPA_RS08185	COG3328	transposase activity
YPA_RS08220	COG3047	cAMP biosynthetic process
YPA_RS08240	COG0134	indole-3-glycerol-phosphate synthase activity
YPA_RS08240	COG0135	phosphoribosylanthranilate isomerase activity
YPA_RS08250	COG0512	Glutamine amidotransferase of anthranilate synthase
YPA_RS08275	COG0009	L-threonylcarbamoyladenylate synthase
YPA_RS08280	COG1187	pseudouridine synthase activity
YPA_RS08290	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS08295	COG0616	signal peptide processing
YPA_RS08315	COG0583	DNA-binding transcription factor activity
YPA_RS08325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPA_RS08335	COG0671	phosphoesterase, PA-phosphatase related
YPA_RS08340	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPA_RS08345	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPA_RS08365	COG0023	Translation Initiation Factor
YPA_RS08385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPA_RS08390	COG2879	small protein
YPA_RS08395	COG1966	Carbon starvation protein
YPA_RS08405	COG2271	Major facilitator Superfamily
YPA_RS08410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPA_RS08415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPA_RS08425	COG4659	FMN binding
YPA_RS08430	COG4658	electron transport chain
YPA_RS08435	COG3708	Transcriptional regulator
YPA_RS08435	COG2207	Transcriptional regulator
YPA_RS08465	COG1132	(ABC) transporter
YPA_RS08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPA_RS08480	COG2274	protein secretion by the type I secretion system
YPA_RS08495	COG1879	ABC-type sugar transport system periplasmic component
YPA_RS08500	COG1129	ABC transporter
YPA_RS08505	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS08515	COG0673	inositol 2-dehydrogenase activity
YPA_RS08520	COG0385	Bile acid
YPA_RS08530	COG5339	Protein conserved in bacteria
YPA_RS08540	COG0114	fumarate hydratase activity
YPA_RS08555	COG0583	DNA-binding transcription factor activity
YPA_RS08560	COG1940	carbohydrate kinase activity
YPA_RS08565	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPA_RS08575	COG1609	Transcriptional regulator
YPA_RS08595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPA_RS08600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPA_RS08625	COG0028	Belongs to the TPP enzyme family
YPA_RS08630	COG0440	acetolactate synthase activity
YPA_RS08635	COG1011	Hydrolase
YPA_RS08655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPA_RS08660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPA_RS08665	COG0589	response to stress
YPA_RS08670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPA_RS08675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPA_RS08690	COG0531	amino acid
YPA_RS08700	COG0745	RESPONSE REGULATOR receiver
YPA_RS08705	COG2205	protein histidine kinase activity
YPA_RS08710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPA_RS08745	COG3038	cytochrome b561
YPA_RS08760	COG3591	Belongs to the peptidase S1B family
YPA_RS08775	COG1643	Atp-dependent helicase
YPA_RS08790	COG1643	Atp-dependent helicase
YPA_RS08800	COG2390	Transcriptional regulator
YPA_RS08805	COG0246	Mannitol dehydrogenase
YPA_RS08810	COG3784	Protein of unknown function (DUF1318)
YPA_RS08820	COG2911	Protein conserved in bacteria
YPA_RS08825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPA_RS08830	COG3187	Heat shock protein
YPA_RS08835	COG3042	response to heat
YPA_RS08840	COG1285	pathogenesis
YPA_RS08850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPA_RS08850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPA_RS08850	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPA_RS08850	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPA_RS08860	COG0657	acetylesterase activity
YPA_RS08875	COG4166	transmembrane transport
YPA_RS08880	COG2866	Carboxypeptidase
YPA_RS08885	COG4948	Mandelate Racemase Muconate Lactonizing
YPA_RS08890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPA_RS08905	COG5642	Protein of unknown function (DUF2384)
YPA_RS08910	COG5654	RES domain protein
YPA_RS08920	COG3106	COG3106 Predicted ATPase
YPA_RS08930	COG1983	PspC domain protein
YPA_RS08940	COG1842	Phage shock protein A
YPA_RS08945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPA_RS08965	COG4166	transmembrane transport
YPA_RS08970	COG4168	peptide transport system, permease
YPA_RS08975	COG4171	peptide transport system, permease
YPA_RS08985	COG4172	Belongs to the ABC transporter superfamily
YPA_RS08990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPA_RS08990	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPA_RS08995	COG3104	oligopeptide transport
YPA_RS09010	COG0625	glutathione transferase activity
YPA_RS09030	COG3895	Periplasmic Protein
YPA_RS09040	COG3133	Outer membrane lipoprotein
YPA_RS09050	COG4989	oxidoreductase activity
YPA_RS09055	COG3313	Fe-S protein
YPA_RS09060	COG2194	sulfuric ester hydrolase activity
YPA_RS09065	COG1309	transcriptional regulator
YPA_RS09070	COG1902	pentaerythritol trinitrate reductase activity
YPA_RS09080	COG0346	lactoylglutathione lyase activity
YPA_RS09085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPA_RS09090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPA_RS09100	COG0791	NLP P60 protein
YPA_RS09115	COG0583	DNA-binding transcription factor activity
YPA_RS09120	COG2814	Major facilitator Superfamily
YPA_RS09125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPA_RS09130	COG0307	riboflavin synthase, alpha
YPA_RS09175	COG1376	ErfK ybiS ycfS ynhG family protein
YPA_RS09175	COG1388	LysM domain
YPA_RS09190	COG0719	Fe-S assembly protein
YPA_RS09195	COG0396	ATPase activity
YPA_RS09200	COG0719	Fe-S assembly protein
YPA_RS09205	COG0316	Belongs to the HesB IscA family
YPA_RS09215	COG2050	protein possibly involved in aromatic compounds catabolism
YPA_RS09220	COG0247	lactate metabolic process
YPA_RS09220	COG0277	FAD linked oxidase domain protein
YPA_RS09225	COG0628	permease
YPA_RS09230	COG0574	Belongs to the PEP-utilizing enzyme family
YPA_RS09230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPA_RS09255	COG0791	NLP P60 protein
YPA_RS09300	COG0386	Belongs to the glutathione peroxidase family
YPA_RS09315	COG0776	regulation of translation
YPA_RS09320	COG0072	phenylalanine-tRNA ligase activity
YPA_RS09320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPA_RS09350	COG4249	Peptidase C14 caspase catalytic subunit p20
YPA_RS09375	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPA_RS09380	COG1121	(ABC) transporter
YPA_RS09385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPA_RS09390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPA_RS09400	COG3001	Fructosamine kinase
YPA_RS09410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPA_RS09415	COG3328	transposase activity
YPA_RS09420	COG1917	Cupin 2, conserved barrel domain protein
YPA_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS09455	COG1175	transmembrane transport
YPA_RS09460	COG0395	ABC-type sugar transport system, permease component
YPA_RS09465	COG3842	ATPase activity
YPA_RS09470	COG1653	transport
YPA_RS09475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPA_RS09480	COG1988	membrane-bound metal-dependent
YPA_RS09485	COG1823	symporter activity
YPA_RS09490	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPA_RS09500	COG0823	Involved in the tonB-independent uptake of proteins
YPA_RS09505	COG2814	Major facilitator Superfamily
YPA_RS09510	COG3121	Chaperone
YPA_RS09525	COG3121	Chaperone
YPA_RS09530	COG3539	Fimbrial protein
YPA_RS09540	COG0793	Belongs to the peptidase S41A family
YPA_RS09550	COG1956	GAF domain-containing protein
YPA_RS09555	COG2995	paraquat-inducible protein a
YPA_RS09560	COG3008	intermembrane lipid transfer
YPA_RS09580	COG3121	Chaperone
YPA_RS09635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPA_RS09645	COG5295	Hep Hag repeat protein
YPA_RS09655	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPA_RS09665	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPA_RS09670	COG0745	RESPONSE REGULATOR receiver
YPA_RS09680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPA_RS09685	COG0840	transmembrane signaling receptor activity
YPA_RS09690	COG0840	transmembrane signaling receptor activity
YPA_RS09710	COG2964	Protein conserved in bacteria
YPA_RS09720	COG0251	oxidation-reduction process
YPA_RS09725	COG2271	Major facilitator Superfamily
YPA_RS09730	COG0835	chemotaxis
YPA_RS09735	COG2198	Histidine kinase
YPA_RS09735	COG0643	Histidine kinase
YPA_RS09740	COG1360	Flagellar Motor Protein
YPA_RS09765	COG1285	pathogenesis
YPA_RS09805	COG0604	alcohol dehydrogenase
YPA_RS09805	COG3321	synthase
YPA_RS09805	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS09815	COG1522	sequence-specific DNA binding
YPA_RS09840	COG1733	regulation of RNA biosynthetic process
YPA_RS09845	COG0702	epimerase
YPA_RS09850	COG0840	transmembrane signaling receptor activity
YPA_RS09865	COG0538	isocitrate dehydrogenase activity
YPA_RS09870	COG1187	pseudouridine synthase activity
YPA_RS09890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPA_RS09900	COG0745	RESPONSE REGULATOR receiver
YPA_RS09910	COG2850	peptidyl-arginine hydroxylation
YPA_RS09925	COG1940	carbohydrate kinase activity
YPA_RS09930	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPA_RS09940	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPA_RS09945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPA_RS09950	COG3134	Outer membrane lipoprotein
YPA_RS09955	COG3328	transposase activity
YPA_RS09970	COG1252	NADH dehydrogenase
YPA_RS09980	COG1472	Belongs to the glycosyl hydrolase 3 family
YPA_RS09995	COG5633	Lipoprotein
YPA_RS10000	COG0537	adenosine 5'-monophosphoramidase activity
YPA_RS10005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPA_RS10025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPA_RS10025	COG1263	PTS System
YPA_RS10030	COG0084	hydrolase, TatD family'
YPA_RS10035	COG0470	DNA polymerase III
YPA_RS10045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPA_RS10050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPA_RS10060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPA_RS10090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPA_RS10095	COG1399	metal-binding, possibly nucleic acid-binding protein
YPA_RS10100	COG0424	maF-like protein
YPA_RS10110	COG0564	pseudouridine synthase activity
YPA_RS10115	COG1530	ribonuclease E activity
YPA_RS10125	COG3328	transposase activity
YPA_RS10130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPA_RS10165	COG3328	transposase activity
YPA_RS10170	COG2197	response regulator
YPA_RS10175	COG0628	permease
YPA_RS10205	COG3916	Acyl-homoserine-lactone synthase
YPA_RS10210	COG2771	luxR family
YPA_RS10215	COG0583	DNA-binding transcription factor activity
YPA_RS10225	COG0477	Major facilitator Superfamily
YPA_RS10235	COG0667	Aldo Keto reductase
YPA_RS10260	COG1203	CRISPR-associated helicase, Cas3
YPA_RS10265	COG1518	maintenance of DNA repeat elements
YPA_RS10270	COG0668	transmembrane transport
YPA_RS10290	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPA_RS10295	COG0395	ABC-type sugar transport system, permease component
YPA_RS10310	COG1609	Transcriptional regulator
YPA_RS10320	COG3842	ATPase activity
YPA_RS10330	COG3210	domain, Protein
YPA_RS10350	COG3210	domain, Protein
YPA_RS10370	COG3210	domain, Protein
YPA_RS10375	COG2831	hemolysin activation secretion protein
YPA_RS10380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPA_RS10385	COG4638	Rieske (2fe-2S)
YPA_RS10390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPA_RS10400	COG0473	3-isopropylmalate dehydrogenase activity
YPA_RS10405	COG0583	DNA-binding transcription factor activity
YPA_RS10410	COG1609	Transcriptional regulator
YPA_RS10415	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS10420	COG1129	ABC transporter
YPA_RS10425	COG1879	ABC-type sugar transport system periplasmic component
YPA_RS10430	COG1063	alcohol dehydrogenase
YPA_RS10460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS10465	COG0765	amino acid transport
YPA_RS10470	COG1126	abc transporter atp-binding protein
YPA_RS10505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPA_RS10520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPA_RS10535	COG1169	isochorismate synthase
YPA_RS10545	COG4575	ribosome binding
YPA_RS10560	COG0129	dihydroxy-acid dehydratase activity
YPA_RS10575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPA_RS10585	COG1609	Transcriptional regulator
YPA_RS10590	COG1649	PFAM Uncharacterised BCR, COG1649
YPA_RS10595	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS10600	COG3265	gluconokinase activity
YPA_RS10605	COG2731	YhcH YjgK YiaL family protein
YPA_RS10620	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPA_RS10625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPA_RS10635	COG0839	Belongs to the complex I subunit 6 family
YPA_RS10650	COG1034	ATP synthesis coupled electron transport
YPA_RS10670	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPA_RS10680	COG0583	DNA-binding transcription factor activity
YPA_RS10690	COG0436	Aminotransferase
YPA_RS10705	COG0471	metal ion transport
YPA_RS10705	COG0490	domain, Protein
YPA_RS10710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPA_RS10735	COG0280	phosphate acetyltransferase
YPA_RS10735	COG0857	belongs to the CobB CobQ family
YPA_RS10740	COG1609	Transcriptional regulator
YPA_RS10755	COG3037	sugar-specific permease SgaT UlaA
YPA_RS10760	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPA_RS10765	COG0622	Phosphoesterase
YPA_RS10775	COG1090	epimerase
YPA_RS10780	COG4598	ABC transporter
YPA_RS10785	COG4160	amino acid transport
YPA_RS10790	COG4215	(ABC) transporter
YPA_RS10795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS10815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPA_RS10820	COG1286	toxin biosynthetic process
YPA_RS10825	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPA_RS10830	COG0285	dihydrofolate synthase activity
YPA_RS10840	COG0586	Pfam SNARE associated Golgi protein
YPA_RS10850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPA_RS10870	COG0697	spore germination
YPA_RS10885	COG1794	racemase activity, acting on amino acids and derivatives
YPA_RS10890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPA_RS10905	COG3101	peptidyl-lysine hydroxylation
YPA_RS10910	COG0730	response to heat
YPA_RS10925	COG2890	protein-(glutamine-N5) methyltransferase activity
YPA_RS10940	COG2062	phosphohistidine phosphatase, SixA
YPA_RS10955	COG3691	Protein conserved in bacteria
YPA_RS10970	COG4235	cytochrome complex assembly
YPA_RS10970	COG3088	subunit of a heme lyase
YPA_RS10975	COG4235	cytochrome complex assembly
YPA_RS10975	COG3088	subunit of a heme lyase
YPA_RS10980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPA_RS10985	COG1138	Cytochrome C-type biogenesis protein
YPA_RS10995	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPA_RS11000	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPA_RS11005	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPA_RS11025	COG1704	LemA family
YPA_RS11035	COG2824	Alkylphosphonate utilization operon protein PhnA
YPA_RS11125	COG3188	usher protein
YPA_RS11130	COG3328	transposase activity
YPA_RS11135	COG3188	usher protein
YPA_RS11140	COG3121	Chaperone
YPA_RS11200	COG2951	lytic endotransglycosylase activity
YPA_RS11235	COG0243	molybdopterin cofactor binding
YPA_RS11240	COG0437	4 iron, 4 sulfur cluster binding
YPA_RS11245	COG3302	dmso reductase anchor subunit
YPA_RS11250	COG3381	protein complex oligomerization
YPA_RS11280	COG3038	cytochrome b561
YPA_RS11285	COG0436	Aminotransferase
YPA_RS11310	COG0667	Aldo Keto reductase
YPA_RS11325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPA_RS11370	COG3530	Putative quorum-sensing-regulated virulence factor
YPA_RS11395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS11420	COG2205	protein histidine kinase activity
YPA_RS11425	COG0745	RESPONSE REGULATOR receiver
YPA_RS11430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPA_RS11445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPA_RS11465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPA_RS11475	COG5002	protein histidine kinase activity
YPA_RS11475	COG3850	Histidine kinase
YPA_RS11480	COG0745	RESPONSE REGULATOR receiver
YPA_RS11495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPA_RS11500	COG4208	sulfate ABC transporter
YPA_RS11505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPA_RS11510	COG4150	thiosulfate binding
YPA_RS11520	COG1737	Transcriptional regulator
YPA_RS11530	COG2731	YhcH YjgK YiaL family protein
YPA_RS11540	COG4886	Leucine-rich repeat (LRR) protein
YPA_RS11550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPA_RS11555	COG2837	iron assimilation
YPA_RS11565	COG3111	PFAM Bacterial OB fold (BOF) protein
YPA_RS11625	COG3005	denitrification pathway
YPA_RS11630	COG3043	anaerobic respiration
YPA_RS11640	COG3062	negative regulation of establishment of protein localization
YPA_RS11645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPA_RS11645	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPA_RS11650	COG2197	response regulator
YPA_RS11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPA_RS11670	COG1988	membrane-bound metal-dependent
YPA_RS11675	COG0641	radical SAM
YPA_RS11680	COG3119	arylsulfatase activity
YPA_RS11685	COG3842	ATPase activity
YPA_RS11690	COG1175	transmembrane transport
YPA_RS11705	COG1393	Belongs to the ArsC family
YPA_RS11715	COG1876	peptidase activity
YPA_RS11735	COG2321	neutral zinc metallopeptidase
YPA_RS11750	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPA_RS11760	COG2716	regulation of RNA biosynthetic process
YPA_RS11765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPA_RS11785	COG0628	permease
YPA_RS11790	COG4783	chaperone-mediated protein folding
YPA_RS11795	COG1393	Belongs to the ArsC family
YPA_RS11820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPA_RS11825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPA_RS11845	COG0581	inorganic phosphate transmembrane transporter activity
YPA_RS11855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPA_RS11870	COG2239	Acts as a magnesium transporter
YPA_RS11875	COG0443	Heat shock 70 kDa protein
YPA_RS11890	COG1177	transmembrane transport
YPA_RS11895	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPA_RS11905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPA_RS11915	COG3842	ATPase activity
YPA_RS11940	COG2205	protein histidine kinase activity
YPA_RS11945	COG2205	protein histidine kinase activity
YPA_RS11950	COG0745	RESPONSE REGULATOR receiver
YPA_RS11955	COG3422	double-strand break repair
YPA_RS11960	COG0826	peptidase U32
YPA_RS11980	COG0351	phosphomethylpyrimidine kinase
YPA_RS11995	COG3328	transposase activity
YPA_RS12050	COG0517	IMP dehydrogenase activity
YPA_RS12050	COG0516	GMP reductase activity
YPA_RS12060	COG1645	bacterial-type flagellum-dependent swarming motility
YPA_RS12075	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPA_RS12080	COG2976	Protein conserved in bacteria
YPA_RS12125	COG3468	outer membrane autotransporter barrel domain protein
YPA_RS12130	COG3468	outer membrane autotransporter barrel domain protein
YPA_RS12150	COG2975	iron-sulfur cluster assembly
YPA_RS12155	COG0633	Ferredoxin
YPA_RS12160	COG0443	Heat shock 70 kDa protein
YPA_RS12175	COG0822	iron-sulfur transferase activity
YPA_RS12180	COG1104	cysteine desulfurase activity
YPA_RS12200	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPA_RS12205	COG3683	transport system, periplasmic component
YPA_RS12210	COG3711	transcriptional antiterminator
YPA_RS12215	COG2814	Major facilitator Superfamily
YPA_RS12235	COG1017	nitric oxide dioxygenase activity
YPA_RS12235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPA_RS12240	COG2188	Transcriptional regulator
YPA_RS12245	COG2188	Transcriptional regulator
YPA_RS12250	COG0347	Belongs to the P(II) protein family
YPA_RS12255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPA_RS12255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPA_RS12260	COG2204	response regulator
YPA_RS12265	COG3170	Tfp pilus assembly protein FimV
YPA_RS12270	COG2205	protein histidine kinase activity
YPA_RS12310	COG0560	Phosphoserine phosphatase
YPA_RS12320	COG1737	Transcriptional regulator
YPA_RS12325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPA_RS12345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPA_RS12365	COG2113	Glycine betaine
YPA_RS12370	COG4176	ABC-type proline glycine betaine transport system permease component
YPA_RS12375	COG4175	Glycine betaine
YPA_RS12380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPA_RS12410	COG3328	transposase activity
YPA_RS12430	COG1278	Cold shock
YPA_RS12435	COG0747	negative chemotaxis
YPA_RS12445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPA_RS12450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPA_RS12455	COG1124	(ABC) transporter
YPA_RS12460	COG0831	urea catabolic process
YPA_RS12485	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPA_RS12495	COG4413	Urea transporter
YPA_RS12500	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPA_RS12515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPA_RS12525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPA_RS12535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPA_RS12540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPA_RS12545	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPA_RS12550	COG2169	Transcriptional regulator
YPA_RS12550	COG1917	Cupin 2, conserved barrel domain protein
YPA_RS12575	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPA_RS12580	COG0033	Phosphoglucomutase
YPA_RS12600	COG0745	RESPONSE REGULATOR receiver
YPA_RS12605	COG2205	protein histidine kinase activity
YPA_RS12640	COG3272	Protein of unknown function (DUF1722)
YPA_RS12650	COG5212	phosphodiesterase
YPA_RS12655	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPA_RS12665	COG1984	allophanate hydrolase subunit 2
YPA_RS12715	COG0513	Belongs to the DEAD box helicase family
YPA_RS12725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPA_RS12740	COG3026	antisigma factor binding
YPA_RS12745	COG3086	response to oxidative stress
YPA_RS12790	COG0582	viral genome integration into host DNA
YPA_RS12795	COG2963	transposase activity
YPA_RS12800	COG0582	viral genome integration into host DNA
YPA_RS12810	COG0596	Alpha beta hydrolase
YPA_RS12830	COG0735	belongs to the Fur family
YPA_RS12860	COG2190	(PTS) system
YPA_RS12860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPA_RS12860	COG1263	PTS System
YPA_RS12870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPA_RS12875	COG1940	carbohydrate kinase activity
YPA_RS12875	COG1846	Transcriptional regulator
YPA_RS12880	COG0647	UMP catabolic process
YPA_RS12885	COG0367	asparagine synthase
YPA_RS12925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPA_RS12930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YPA_RS12935	COG1702	phosphate starvation-inducible protein PhoH
YPA_RS12945	COG4535	Mg2 and Co2 transporter CorC
YPA_RS12950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPA_RS12960	COG0765	amino acid transport
YPA_RS12965	COG0765	amino acid transport
YPA_RS12970	COG1126	abc transporter atp-binding protein
YPA_RS12975	COG2888	peptidyl-tyrosine sulfation
YPA_RS12990	COG1466	dna polymerase III delta subunit
YPA_RS13000	COG0799	negative regulation of ribosome biogenesis
YPA_RS13010	COG0768	penicillin binding
YPA_RS13015	COG0772	Belongs to the SEDS family
YPA_RS13020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPA_RS13035	COG1686	Belongs to the peptidase S11 family
YPA_RS13055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPA_RS13065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPA_RS13075	COG1278	Cold shock
YPA_RS13080	COG2197	response regulator
YPA_RS13105	COG5265	(ABC) transporter
YPA_RS13115	COG3718	enzyme involved in inositol metabolism
YPA_RS13130	COG0673	inositol 2-dehydrogenase activity
YPA_RS13135	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS13140	COG1129	ABC transporter
YPA_RS13155	COG3962	Belongs to the TPP enzyme family
YPA_RS13180	COG2373	Large extracellular alpha-helical protein
YPA_RS13185	COG4953	penicillin-binding protein 1C
YPA_RS13190	COG3328	transposase activity
YPA_RS13195	COG4953	penicillin-binding protein 1C
YPA_RS13200	COG3423	Transcriptional regulator
YPA_RS13245	COG2850	peptidyl-arginine hydroxylation
YPA_RS13250	COG3328	transposase activity
YPA_RS13265	COG1472	Belongs to the glycosyl hydrolase 3 family
YPA_RS13285	COG0656	L-ascorbic acid biosynthetic process
YPA_RS13290	COG0667	Aldo Keto reductase
YPA_RS13320	COG2453	phosphatase
YPA_RS13320	COG0671	phosphoesterase, PA-phosphatase related
YPA_RS13325	COG2267	carboxylic ester hydrolase activity
YPA_RS13335	COG4589	Belongs to the CDS family
YPA_RS13340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPA_RS13390	COG2501	S4 domain
YPA_RS13410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPA_RS13420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPA_RS13425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPA_RS13430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPA_RS13435	COG4181	ATPase activity
YPA_RS13440	COG2755	lipolytic protein G-D-S-L family
YPA_RS13445	COG0300	oxidoreductase activity
YPA_RS13450	COG3118	belongs to the thioredoxin family
YPA_RS13455	COG0330	HflC and HflK could
YPA_RS13460	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPA_RS13465	COG0789	Transcriptional regulator
YPA_RS13470	COG2217	Heavy metal translocating P-type atpase
YPA_RS13475	COG3735	TraB family
YPA_RS13480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPA_RS13495	COG0737	Belongs to the 5'-nucleotidase family
YPA_RS13500	COG0737	Belongs to the 5'-nucleotidase family
YPA_RS13505	COG0737	Belongs to the 5'-nucleotidase family
YPA_RS13510	COG2223	nitrite transmembrane transporter activity
YPA_RS13515	COG4651	solute:proton antiporter activity
YPA_RS13515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPA_RS13520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPA_RS13525	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPA_RS13545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPA_RS13585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPA_RS13610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPA_RS13610	COG0543	2 iron, 2 sulfur cluster binding
YPA_RS13640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPA_RS13665	COG3264	Mechanosensitive ion channel
YPA_RS13665	COG1196	nuclear chromosome segregation
YPA_RS13680	COG1196	nuclear chromosome segregation
YPA_RS13680	COG3264	Mechanosensitive ion channel
YPA_RS13685	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPA_RS13690	COG1309	transcriptional regulator
YPA_RS13695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPA_RS13700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPA_RS13710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPA_RS13730	COG3695	enzyme binding
YPA_RS13735	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPA_RS13740	COG1946	Acyl-CoA thioesterase
YPA_RS13745	COG0004	ammonium transporteR
YPA_RS13750	COG0347	Belongs to the P(II) protein family
YPA_RS13755	COG1132	(ABC) transporter
YPA_RS13760	COG1132	(ABC) transporter
YPA_RS13765	COG1522	sequence-specific DNA binding
YPA_RS13780	COG4533	DNA binding
YPA_RS13790	COG0824	Thioesterase
YPA_RS13795	COG1555	photosystem II stabilization
YPA_RS13800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPA_RS13805	COG0776	regulation of translation
YPA_RS13810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPA_RS13835	COG0271	Belongs to the BolA IbaG family
YPA_RS13840	COG3056	Lipoprotein
YPA_RS13845	COG2223	nitrite transmembrane transporter activity
YPA_RS13860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPA_RS13865	COG1845	cytochrome c oxidase, subunit III
YPA_RS13870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPA_RS13880	COG2814	Major facilitator Superfamily
YPA_RS13890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPA_RS13895	COG0693	protein deglycase activity
YPA_RS13915	COG0142	geranyltranstransferase activity
YPA_RS13935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPA_RS13940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPA_RS13955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPA_RS13955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPA_RS13990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPA_RS13995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPA_RS14000	COG1862	Preprotein translocase
YPA_RS14020	COG0450	alkyl hydroperoxide reductase
YPA_RS14045	COG0366	Alpha amylase catalytic
YPA_RS14065	COG5002	protein histidine kinase activity
YPA_RS14070	COG0745	RESPONSE REGULATOR receiver
YPA_RS14080	COG0420	3'-5' exonuclease activity
YPA_RS14085	COG0419	ATPase involved in DNA repair
YPA_RS14100	COG0419	ATPase involved in DNA repair
YPA_RS14105	COG1940	carbohydrate kinase activity
YPA_RS14140	COG2226	methyltransferase
YPA_RS14200	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPA_RS14220	COG1477	protein flavinylation
YPA_RS14240	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPA_RS14245	COG1805	sodium ion transport
YPA_RS14255	COG3034	peptidoglycan biosynthetic process
YPA_RS14260	COG0121	glutamine amidotransferase
YPA_RS14270	COG1960	acyl-CoA dehydrogenase activity
YPA_RS14280	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPA_RS14300	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPA_RS14315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPA_RS14325	COG0765	amino acid transport
YPA_RS14365	COG2814	Major facilitator Superfamily
YPA_RS14370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPA_RS14380	COG1846	Transcriptional regulator
YPA_RS14385	COG1566	PFAM secretion protein HlyD family protein
YPA_RS14390	COG2814	Major facilitator Superfamily
YPA_RS14395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPA_RS14400	COG3118	belongs to the thioredoxin family
YPA_RS14405	COG3148	PFAM DTW domain containing protein
YPA_RS14410	COG0045	succinate-CoA ligase (ADP-forming) activity
YPA_RS14410	COG1042	CoA-binding domain protein
YPA_RS14410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPA_RS14415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPA_RS14420	COG5544	Lipoprotein
YPA_RS14455	COG0542	response to heat
YPA_RS14465	COG0564	pseudouridine synthase activity
YPA_RS14470	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPA_RS14475	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPA_RS14500	COG0077	Prephenate dehydratase
YPA_RS14500	COG1605	Chorismate mutase
YPA_RS14530	COG0529	Catalyzes the synthesis of activated sulfate
YPA_RS14570	COG4942	peptidase
YPA_RS14570	COG1388	LysM domain
YPA_RS14575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPA_RS14590	COG0698	ribose 5-phosphate isomerase
YPA_RS14595	COG1063	alcohol dehydrogenase
YPA_RS14600	COG1028	Short-chain dehydrogenase reductase Sdr
YPA_RS14605	COG2376	Dihydroxyacetone kinase
YPA_RS14620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPA_RS14640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS14645	COG1858	cytochrome C peroxidase
YPA_RS14655	COG4771	TonB-dependent receptor
YPA_RS14675	COG0024	Methionine aminopeptidase
YPA_RS14685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPA_RS14685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPA_RS14690	COG1070	Carbohydrate kinase
YPA_RS14695	COG3623	hexulose-6-phosphate isomerase
YPA_RS14700	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS14705	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS14710	COG1129	ABC transporter
YPA_RS14725	COG1349	DNA-binding transcription factor activity
YPA_RS14730	COG0235	Class ii aldolase
YPA_RS14735	COG0243	molybdopterin cofactor binding
YPA_RS14740	COG0437	4 iron, 4 sulfur cluster binding
YPA_RS14745	COG3302	dmso reductase anchor subunit
YPA_RS14750	COG3381	protein complex oligomerization
YPA_RS14755	COG3038	cytochrome b561
YPA_RS14760	COG3783	Cytochrome b(562)
YPA_RS14770	COG1879	ABC-type sugar transport system periplasmic component
YPA_RS14780	COG1129	ABC transporter
YPA_RS14785	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS14790	COG3959	Transketolase, thiamine diphosphate binding domain
YPA_RS14795	COG3958	Transketolase
YPA_RS14800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPA_RS14840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPA_RS14845	COG1238	metal cluster binding
YPA_RS14850	COG2918	glutathione biosynthetic process
YPA_RS14870	COG4536	flavin adenine dinucleotide binding
YPA_RS14875	COG4137	Cytochrome C assembly protein
YPA_RS14880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPA_RS14910	COG3137	Salt-induced outer membrane protein
YPA_RS14915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPA_RS14920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPA_RS14925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPA_RS14930	COG3279	Response regulator of the LytR AlgR family
YPA_RS14935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPA_RS14940	COG1605	Chorismate mutase
YPA_RS14940	COG0287	Prephenate dehydrogenase
YPA_RS14945	COG1605	Chorismate mutase
YPA_RS14945	COG0077	Prephenate dehydratase
YPA_RS14995	COG0720	synthase
YPA_RS15000	COG0602	queuosine metabolic process
YPA_RS15020	COG3956	TIGRFAM MazG family protein
YPA_RS15030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPA_RS15035	COG2205	protein histidine kinase activity
YPA_RS15035	COG3437	response regulator, receiver
YPA_RS15035	COG3850	Histidine kinase
YPA_RS15035	COG4999	Histidine kinase
YPA_RS15040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPA_RS15060	COG2860	membrane
YPA_RS15080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPA_RS15085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPA_RS15095	COG1120	ATPase activity
YPA_RS15100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPA_RS15105	COG1643	Atp-dependent helicase
YPA_RS15110	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPA_RS15125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPA_RS15130	COG0617	tRNA 3'-terminal CCA addition
YPA_RS15135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPA_RS15160	COG0842	Transport permease protein
YPA_RS15165	COG1131	(ABC) transporter
YPA_RS15170	COG0288	reversible hydration of carbon dioxide
YPA_RS15175	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPA_RS15180	COG2132	Multicopper oxidase
YPA_RS15200	COG0697	spore germination
YPA_RS15210	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPA_RS15225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPA_RS15230	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPA_RS15235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPA_RS15240	COG2186	Transcriptional regulator
YPA_RS15245	COG1113	amino acid transport
YPA_RS15250	COG3725	Membrane protein required for beta-lactamase induction
YPA_RS15255	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPA_RS15265	COG4969	Belongs to the N-Me-Phe pilin family
YPA_RS15270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPA_RS15275	COG1459	type II secretion system
YPA_RS15330	COG0582	viral genome integration into host DNA
YPA_RS15340	COG0795	lipopolysaccharide-transporting ATPase activity
YPA_RS15345	COG0795	lipopolysaccharide-transporting ATPase activity
YPA_RS15355	COG2927	DNA polymerase III (CHI subunit)
YPA_RS15360	COG0525	valine-tRNA ligase activity
YPA_RS15370	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPA_RS15380	COG2731	YhcH YjgK YiaL family protein
YPA_RS15390	COG0601	transmembrane transport
YPA_RS15395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPA_RS15400	COG0444	Belongs to the ABC transporter superfamily
YPA_RS15405	COG4608	Belongs to the ABC transporter superfamily
YPA_RS15420	COG2188	Transcriptional regulator
YPA_RS15425	COG3624	Phosphonate C-P lyase system protein PhnG
YPA_RS15430	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPA_RS15435	COG3626	phosphonate metabolism
YPA_RS15440	COG3627	carbon phosphorus lyase activity
YPA_RS15445	COG4107	phosphonate C-P lyase system protein PhnK
YPA_RS15450	COG4778	phosphonate C-P lyase system protein PhnL
YPA_RS15455	COG3454	Phosphonate metabolism
YPA_RS15460	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPA_RS15465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPA_RS15470	COG0702	epimerase
YPA_RS15485	COG3842	ATPase activity
YPA_RS15490	COG0395	ABC-type sugar transport system, permease component
YPA_RS15495	COG1175	transmembrane transport
YPA_RS15500	COG1653	transport
YPA_RS15520	COG3153	acetyltransferase
YPA_RS15525	COG3154	lipid carrier protein
YPA_RS15535	COG0826	peptidase U32
YPA_RS15540	COG0826	peptidase U32
YPA_RS15550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPA_RS15560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPA_RS15580	COG0513	Belongs to the DEAD box helicase family
YPA_RS15595	COG2801	Transposase and inactivated derivatives
YPA_RS15605	COG2423	ornithine cyclodeaminase activity
YPA_RS15610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPA_RS15615	COG0823	Involved in the tonB-independent uptake of proteins
YPA_RS15620	COG0823	Involved in the tonB-independent uptake of proteins
YPA_RS15625	COG5645	(Lipo)protein
YPA_RS15645	COG3977	Valine--pyruvate aminotransferase
YPA_RS15655	COG0366	Alpha amylase catalytic
YPA_RS15670	COG2885	chlorophyll binding
YPA_RS15680	COG2818	Glycosylase
YPA_RS15700	COG2213	PTS system mannitol-specific
YPA_RS15700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS15710	COG3722	fumarate hydratase activity
YPA_RS15750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPA_RS15760	COG3383	formate dehydrogenase (NAD+) activity
YPA_RS15760	COG0243	molybdopterin cofactor binding
YPA_RS15765	COG0243	molybdopterin cofactor binding
YPA_RS15765	COG3383	formate dehydrogenase (NAD+) activity
YPA_RS15770	COG0437	4 iron, 4 sulfur cluster binding
YPA_RS15775	COG2864	formate dehydrogenase
YPA_RS15790	COG3276	selenocysteine insertion sequence binding
YPA_RS15825	COG2801	Transposase and inactivated derivatives
YPA_RS15870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPA_RS15875	COG1191	sigma factor activity
YPA_RS15900	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPA_RS15920	COG3710	Transcriptional regulator
YPA_RS15940	COG1256	bacterial-type flagellum assembly
YPA_RS15950	COG1706	bacterial-type flagellum-dependent cell motility
YPA_RS15960	COG4786	Flagellar basal body rod
YPA_RS15965	COG4787	bacterial-type flagellum-dependent cell motility
YPA_RS15970	COG1749	Flagellar hook protein flgE
YPA_RS15975	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPA_RS15980	COG1558	bacterial-type flagellum-dependent cell motility
YPA_RS15985	COG1815	bacterial-type flagellum-dependent cell motility
YPA_RS15990	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPA_RS16045	COG1677	Flagellar hook-basal body complex protein FliE
YPA_RS16070	COG1987	bacterial-type flagellum assembly
YPA_RS16075	COG1684	flagellar biosynthetic protein fliR
YPA_RS16080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPA_RS16100	COG4592	Periplasmic binding protein
YPA_RS16135	COG4964	Belongs to the GSP D family
YPA_RS16140	COG4964	Belongs to the GSP D family
YPA_RS16190	COG0848	biopolymer transport protein
YPA_RS16195	COG0811	peptide transport
YPA_RS16200	COG0626	cystathionine gamma-synthase activity
YPA_RS16210	COG2207	Transcriptional regulator
YPA_RS16215	COG1979	alcohol dehydrogenase
YPA_RS16225	COG0656	L-ascorbic acid biosynthetic process
YPA_RS16235	COG2132	Multicopper oxidase
YPA_RS16245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPA_RS16255	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPA_RS16260	COG0583	DNA-binding transcription factor activity
YPA_RS16270	COG3150	esterase
YPA_RS16280	COG3151	Protein conserved in bacteria
YPA_RS16285	COG0494	nUDIX hydrolase
YPA_RS16290	COG1538	Outer membrane efflux protein
YPA_RS16305	COG0754	glutathionylspermidine amidase activity
YPA_RS16310	COG3384	dioxygenase
YPA_RS16330	COG0531	amino acid
YPA_RS16345	COG3025	triphosphatase activity
YPA_RS16350	COG4991	sh3 domain protein
YPA_RS16365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPA_RS16380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YPA_RS16385	COG0358	DNA primase activity
YPA_RS16480	COG0251	oxidation-reduction process
YPA_RS16500	COG0436	Aminotransferase
YPA_RS16525	COG1289	transmembrane transporter activity
YPA_RS16545	COG0395	ABC-type sugar transport system, permease component
YPA_RS16555	COG2182	Extracellular solute-binding protein
YPA_RS16560	COG1609	Transcriptional regulator
YPA_RS16565	COG3459	Glycosyltransferase 36 associated
YPA_RS16570	COG3842	ATPase activity
YPA_RS16590	COG3210	domain, Protein
YPA_RS16595	COG3210	domain, Protein
YPA_RS16620	COG3210	domain, Protein
YPA_RS16625	COG2831	hemolysin activation secretion protein
YPA_RS16630	COG4245	von Willebrand factor, type A
YPA_RS16645	COG4245	von Willebrand factor, type A
YPA_RS16665	COG3247	response to pH
YPA_RS16670	COG1902	pentaerythritol trinitrate reductase activity
YPA_RS16670	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPA_RS16685	COG1451	nucleotide metabolic process
YPA_RS16690	COG0673	inositol 2-dehydrogenase activity
YPA_RS16710	COG2721	sulfolactate sulfo-lyase activity
YPA_RS16730	COG2271	Major facilitator Superfamily
YPA_RS16745	COG0586	Pfam SNARE associated Golgi protein
YPA_RS16765	COG4575	ribosome binding
YPA_RS16770	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPA_RS16780	COG2259	Doxx family
YPA_RS16785	COG0435	Glutathione S-transferase
YPA_RS16800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPA_RS16815	COG0551	DNA topoisomerase type I activity
YPA_RS16825	COG0758	DNA mediated transformation
YPA_RS16855	COG3036	rescue of stalled ribosome
YPA_RS16860	COG0789	Transcriptional regulator
YPA_RS16875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPA_RS16890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPA_RS16895	COG0201	protein transport
YPA_RS16905	COG1841	ribosomal large subunit assembly
YPA_RS16945	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPA_RS16950	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPA_RS16960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPA_RS16975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPA_RS16985	COG0089	rRNA binding
YPA_RS17000	COG0051	transcription antitermination factor activity, RNA binding
YPA_RS17040	COG0049	tRNA binding
YPA_RS17045	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPA_RS17065	COG2964	Protein conserved in bacteria
YPA_RS17070	COG0545	Peptidyl-prolyl cis-trans isomerase
YPA_RS17080	COG1047	Peptidyl-prolyl cis-trans
YPA_RS17085	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPA_RS17105	COG1216	Glycosyl transferase, family 2
YPA_RS17115	COG2175	clavaminate synthase activity
YPA_RS17120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPA_RS17130	COG4521	taurine ABC transporter
YPA_RS17140	COG0429	hydrolase of the alpha beta-hydrolase fold
YPA_RS17150	COG3954	Phosphoribulokinase
YPA_RS17160	COG1765	OsmC-like protein
YPA_RS17170	COG1289	transmembrane transporter activity
YPA_RS17185	COG0433	COG0433 Predicted ATPase
YPA_RS17190	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPA_RS17195	COG1486	melibiose metabolic process
YPA_RS17215	COG0402	S-adenosylhomocysteine deaminase activity
YPA_RS17220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPA_RS17240	COG0180	Tryptophanyl-tRNA synthetase
YPA_RS17245	COG0546	phosphoglycolate phosphatase activity
YPA_RS17250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPA_RS17275	COG4796	Type ii and iii secretion system protein
YPA_RS17305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPA_RS17310	COG0494	nUDIX hydrolase
YPA_RS17325	COG1011	Hydrolase
YPA_RS17330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPA_RS17355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPA_RS17360	COG2183	response to ionizing radiation
YPA_RS17370	COG1918	ferrous iron import across plasma membrane
YPA_RS17405	COG1640	4-alpha-glucanotransferase
YPA_RS17410	COG0058	SHG alpha-glucan phosphorylase activity
YPA_RS17415	COG0058	SHG alpha-glucan phosphorylase activity
YPA_RS17435	COG1349	DNA-binding transcription factor activity
YPA_RS17455	COG2801	Transposase and inactivated derivatives
YPA_RS17460	COG5001	Diguanylate cyclase
YPA_RS17470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPA_RS17520	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPA_RS17525	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPA_RS17530	COG4771	TonB-dependent receptor
YPA_RS17550	COG3433	isochorismatase activity
YPA_RS17550	COG2226	methyltransferase
YPA_RS17550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPA_RS17560	COG3433	isochorismatase activity
YPA_RS17560	COG2226	methyltransferase
YPA_RS17560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPA_RS17585	COG1132	(ABC) transporter
YPA_RS17585	COG2375	cellular response to nickel ion
YPA_RS17590	COG1132	(ABC) transporter
YPA_RS17605	COG2610	gluconate transmembrane transporter activity
YPA_RS17620	COG3501	Rhs element vgr protein
YPA_RS17630	COG3209	COG3209 Rhs family protein
YPA_RS17645	COG0471	metal ion transport
YPA_RS17660	COG2801	Transposase and inactivated derivatives
YPA_RS17735	COG3501	Rhs element vgr protein
YPA_RS17780	COG3501	Rhs element vgr protein
YPA_RS17790	COG3209	COG3209 Rhs family protein
YPA_RS17835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YPA_RS17865	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPA_RS17870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPA_RS17875	COG1739	Uncharacterized protein family UPF0029
YPA_RS17885	COG1739	Uncharacterized protein family UPF0029
YPA_RS17910	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YPA_RS17975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPA_RS17980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPA_RS17985	COG1494	fructose-1,6-bisphosphatase
YPA_RS17995	COG3152	Membrane
YPA_RS18010	COG0583	DNA-binding transcription factor activity
YPA_RS18015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPA_RS18020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPA_RS18025	COG0471	metal ion transport
YPA_RS18035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPA_RS18055	COG3678	ATP-independent chaperone mediated protein folding
YPA_RS18060	COG0745	RESPONSE REGULATOR receiver
YPA_RS18065	COG2205	protein histidine kinase activity
YPA_RS18070	COG2169	Transcriptional regulator
YPA_RS18070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPA_RS18075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPA_RS18080	COG1045	serine acetyltransferase
YPA_RS18100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPA_RS18105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPA_RS18115	COG4942	peptidase
YPA_RS18130	COG0156	8-amino-7-oxononanoate synthase activity
YPA_RS18140	COG0859	PFAM glycosyl transferase family 9
YPA_RS18145	COG0859	PFAM glycosyl transferase family 9
YPA_RS18150	COG1519	Transferase
YPA_RS18185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPA_RS18210	COG1561	YicC-like family, N-terminal region
YPA_RS18215	COG2860	membrane
YPA_RS18235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPA_RS18240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPA_RS18245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPA_RS18250	COG0786	glutamate:sodium symporter activity
YPA_RS18255	COG2233	PERMEase
YPA_RS18260	COG2982	Protein involved in outer membrane biogenesis
YPA_RS18265	COG0456	acetyltransferase
YPA_RS18290	COG1011	Hydrolase
YPA_RS18305	COG0174	glutamine synthetase
YPA_RS18320	COG3852	Histidine kinase
YPA_RS18330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPA_RS18355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPA_RS18355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPA_RS18360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPA_RS18365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPA_RS18370	COG3084	Protein conserved in bacteria
YPA_RS18380	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPA_RS18385	COG3328	transposase activity
YPA_RS18425	COG0494	nUDIX hydrolase
YPA_RS18450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPA_RS18455	COG0849	cell division
YPA_RS18460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPA_RS18480	COG0772	Belongs to the SEDS family
YPA_RS18495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPA_RS18500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPA_RS18505	COG0768	penicillin binding
YPA_RS18510	COG3116	cell division
YPA_RS18530	COG1609	Transcriptional regulator
YPA_RS18550	COG0028	Belongs to the TPP enzyme family
YPA_RS18560	COG1022	Amp-dependent synthetase and ligase
YPA_RS18590	COG0473	3-isopropylmalate dehydrogenase activity
YPA_RS18605	COG2814	Major facilitator Superfamily
YPA_RS18620	COG2814	Major facilitator Superfamily
YPA_RS18640	COG4143	(ABC) transporter
YPA_RS18645	COG1178	ABC-type Fe3 transport system permease component
YPA_RS18650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YPA_RS18655	COG0586	Pfam SNARE associated Golgi protein
YPA_RS18660	COG0417	DNA replication proofreading
YPA_RS18680	COG3047	cAMP biosynthetic process
YPA_RS18680	COG2885	chlorophyll binding
YPA_RS18765	COG2801	Transposase and inactivated derivatives
YPA_RS18815	COG0151	Belongs to the GarS family
YPA_RS18835	COG1515	deoxyribonuclease V activity
YPA_RS18875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPA_RS18940	COG0250	Participates in transcription elongation, termination and antitermination
YPA_RS18985	COG0673	inositol 2-dehydrogenase activity
YPA_RS18990	COG2207	Transcriptional regulator
YPA_RS18990	COG1917	Cupin 2, conserved barrel domain protein
YPA_RS18995	COG1869	D-ribose catabolic process
YPA_RS19000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPA_RS19005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPA_RS19010	COG0431	NADPH-dependent FMN reductase
YPA_RS19015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPA_RS19025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPA_RS19035	COG3077	Addiction module antitoxin, RelB DinJ family
YPA_RS19040	COG2252	PERMEase
YPA_RS19045	COG0025	NhaP-type Na H and K H
YPA_RS19055	COG1560	Kdo2-lipid A biosynthetic process
YPA_RS19065	COG1129	ABC transporter
YPA_RS19070	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS19080	COG1069	ribulokinase activity
YPA_RS19090	COG0625	glutathione transferase activity
YPA_RS19115	COG1278	Cold shock
YPA_RS19120	COG1278	Cold shock
YPA_RS19130	COG3133	Outer membrane lipoprotein
YPA_RS19135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPA_RS19145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPA_RS19165	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPA_RS19170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPA_RS19180	COG4145	pantothenate transmembrane transporter activity
YPA_RS19185	COG3924	membrane
YPA_RS19190	COG0439	Biotin carboxylase
YPA_RS19195	COG0511	ligase activity, forming carbon-carbon bonds
YPA_RS19210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPA_RS19215	COG0604	alcohol dehydrogenase
YPA_RS19220	COG2199	diguanylate cyclase activity
YPA_RS19220	COG2200	EAL domain
YPA_RS19225	COG1077	Cell shape determining protein MreB Mrl
YPA_RS19230	COG1792	Involved in formation and maintenance of cell shape
YPA_RS19235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPA_RS19240	COG0424	maF-like protein
YPA_RS19245	COG1530	ribonuclease E activity
YPA_RS19250	COG3164	Protein of unknown function
YPA_RS19255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPA_RS19260	COG0312	modulator of DNA gyrase
YPA_RS19310	COG0583	DNA-binding transcription factor activity
YPA_RS19330	COG1012	belongs to the aldehyde dehydrogenase family
YPA_RS19345	COG2732	(Barnase) inhibitor
YPA_RS19355	COG0312	modulator of DNA gyrase
YPA_RS19365	COG3783	Cytochrome b(562)
YPA_RS19370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPA_RS19375	COG0366	Alpha amylase catalytic
YPA_RS19380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPA_RS19380	COG1263	PTS System
YPA_RS19385	COG1609	Transcriptional regulator
YPA_RS19410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS19430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPA_RS19435	COG1137	ATPase activity
YPA_RS19440	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPA_RS19445	COG3117	lipopolysaccharide transmembrane transporter activity
YPA_RS19450	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPA_RS19455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPA_RS19455	COG0517	IMP dehydrogenase activity
YPA_RS19460	COG0530	calcium, potassium:sodium antiporter activity
YPA_RS19465	COG1127	ABC transporter
YPA_RS19470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPA_RS19475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPA_RS19480	COG2854	intermembrane phospholipid transfer
YPA_RS19485	COG3113	response to antibiotic
YPA_RS19490	COG5007	Belongs to the BolA IbaG family
YPA_RS19500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPA_RS19510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPA_RS19515	COG3105	Protein conserved in bacteria
YPA_RS19520	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPA_RS19540	COG0625	glutathione transferase activity
YPA_RS19545	COG2969	positive regulation of protein catabolic process
YPA_RS19555	COG0493	'glutamate synthase
YPA_RS19560	COG0067	glutamate synthase
YPA_RS19560	COG0070	glutamate synthase
YPA_RS19560	COG0069	glutamate synthase activity
YPA_RS19565	COG1242	4 iron, 4 sulfur cluster binding
YPA_RS19575	COG0784	Response regulator, receiver
YPA_RS19575	COG2198	Histidine kinase
YPA_RS19575	COG5002	protein histidine kinase activity
YPA_RS19585	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPA_RS19595	COG2823	Periplasmic or secreted lipoprotein
YPA_RS19615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPA_RS19620	COG1741	Belongs to the pirin family
YPA_RS19625	COG0583	DNA-binding transcription factor activity
YPA_RS19630	COG0435	Glutathione S-transferase
YPA_RS19650	COG2801	Transposase and inactivated derivatives
YPA_RS19670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPA_RS19675	COG0058	SHG alpha-glucan phosphorylase activity
YPA_RS19700	COG3275	phosphorelay sensor kinase activity
YPA_RS19730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPA_RS19735	COG2095	MarC family integral membrane protein
YPA_RS19755	COG3265	gluconokinase activity
YPA_RS19760	COG2610	gluconate transmembrane transporter activity
YPA_RS19765	COG1609	Transcriptional regulator
YPA_RS19770	COG1741	Belongs to the pirin family
YPA_RS19790	COG0191	fructose-bisphosphate aldolase activity
YPA_RS19805	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPA_RS19820	COG2081	HI0933 family
YPA_RS19825	COG0306	phosphate transporter
YPA_RS19840	COG0589	response to stress
YPA_RS19860	COG0339	signal peptide processing
YPA_RS19865	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPA_RS19870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPA_RS19875	COG3835	regulator
YPA_RS19880	COG2610	gluconate transmembrane transporter activity
YPA_RS19885	COG1929	Belongs to the glycerate kinase type-1 family
YPA_RS19910	COG1295	ribonuclease BN
YPA_RS19915	COG2134	cdp-diacylglycerol pyrophosphatase
YPA_RS19920	COG2982	Protein involved in outer membrane biogenesis
YPA_RS19925	COG2200	EAL domain
YPA_RS19930	COG1942	4-Oxalocrotonate Tautomerase
YPA_RS19935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPA_RS19940	COG0612	Peptidase, M16
YPA_RS19960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPA_RS19965	COG2200	EAL domain
YPA_RS19965	COG2199	diguanylate cyclase activity
YPA_RS19970	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPA_RS19975	COG4608	Belongs to the ABC transporter superfamily
YPA_RS19980	COG0444	Belongs to the ABC transporter superfamily
YPA_RS19985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPA_RS19990	COG0601	transmembrane transport
YPA_RS19995	COG0747	negative chemotaxis
YPA_RS20005	COG2831	hemolysin activation secretion protein
YPA_RS20025	COG2271	Major facilitator Superfamily
YPA_RS20045	COG0488	(ABC) transporter
YPA_RS20065	COG0560	Phosphoserine phosphatase
YPA_RS20070	COG3726	membrane protein affecting hemolysin expression
YPA_RS20100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPA_RS20105	COG0084	hydrolase, TatD family'
YPA_RS20110	COG4667	esterase of the alpha-beta hydrolase superfamily
YPA_RS20120	COG2823	Periplasmic or secreted lipoprotein
YPA_RS20130	COG0456	acetyltransferase
YPA_RS20135	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPA_RS20180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPA_RS20185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPA_RS20205	COG0859	PFAM glycosyl transferase family 9
YPA_RS20210	COG1070	Carbohydrate kinase
YPA_RS20260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS20260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPA_RS20260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPA_RS20265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPA_RS20270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPA_RS20275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPA_RS20280	COG2207	Transcriptional regulator
YPA_RS20290	COG4269	membrane
YPA_RS20345	COG2963	transposase activity
YPA_RS20360	COG1401	restriction endodeoxyribonuclease activity
YPA_RS20380	COG3650	response to hydrogen peroxide
YPA_RS20385	COG1960	acyl-CoA dehydrogenase activity
YPA_RS20390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPA_RS20395	COG0557	exoribonuclease II activity
YPA_RS20410	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPA_RS20415	COG0330	HflC and HflK could
YPA_RS20420	COG0330	HflC and HflK could
YPA_RS20425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPA_RS20445	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPA_RS20450	COG0802	atpase or kinase
YPA_RS20455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPA_RS20455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPA_RS20460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPA_RS20475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPA_RS20495	COG3264	Mechanosensitive ion channel
YPA_RS20495	COG1511	domain protein
YPA_RS20510	COG1053	succinate dehydrogenase
YPA_RS20515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPA_RS20525	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPA_RS20570	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPA_RS20585	COG3383	formate dehydrogenase (NAD+) activity
YPA_RS20590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPA_RS20595	COG0493	'glutamate synthase
YPA_RS20595	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPA_RS20600	COG1309	transcriptional regulator
YPA_RS20670	COG1454	alcohol dehydrogenase
YPA_RS20685	COG1454	alcohol dehydrogenase
YPA_RS20695	COG0629	single-stranded DNA binding
YPA_RS20700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPA_RS20705	COG2315	Protein conserved in bacteria
YPA_RS20710	COG1448	Aminotransferase
YPA_RS20735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPA_RS20740	COG0735	belongs to the Fur family
YPA_RS20750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPA_RS20795	COG3121	Chaperone
YPA_RS20855	COG1358	cellular component organization or biogenesis
YPA_RS20880	COG3721	Heme iron utilization protein
YPA_RS20885	COG0702	epimerase
YPA_RS20890	COG4771	TonB-dependent receptor
YPA_RS20895	COG3720	iron ion transport
YPA_RS20900	COG4558	Periplasmic binding protein
YPA_RS20905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPA_RS20915	COG0626	cystathionine gamma-synthase activity
YPA_RS20920	COG0814	amino acid
YPA_RS20925	COG0583	DNA-binding transcription factor activity
YPA_RS20930	COG0425	Belongs to the sulfur carrier protein TusA family
YPA_RS20935	COG2391	methyltransferase activity
YPA_RS21045	COG1301	dicarboxylic acid transport
YPA_RS21055	COG3162	membrane
YPA_RS21085	COG2885	chlorophyll binding
YPA_RS21090	COG2199	diguanylate cyclase activity
YPA_RS21105	COG0741	lytic transglycosylase activity
YPA_RS21110	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPA_RS21125	COG3708	Transcriptional regulator
YPA_RS21125	COG2207	Transcriptional regulator
YPA_RS21130	COG3045	CreA protein
YPA_RS21135	COG0745	RESPONSE REGULATOR receiver
YPA_RS21165	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPA_RS21180	COG1584	GPR1 FUN34 yaaH family protein
YPA_RS21200	COG0583	DNA-binding transcription factor activity
YPA_RS21215	COG0196	riboflavin kinase activity
YPA_RS21230	COG1047	Peptidyl-prolyl cis-trans
YPA_RS21265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPA_RS21270	COG1280	lysine exporter protein (LysE YggA)
YPA_RS21275	COG2966	Psort location CytoplasmicMembrane, score
YPA_RS21285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPA_RS21335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPA_RS21340	COG0564	pseudouridine synthase activity
YPA_RS21375	COG3851	Histidine kinase
YPA_RS21380	COG2197	response regulator
YPA_RS21385	COG2194	sulfuric ester hydrolase activity
YPA_RS21400	COG2986	histidine ammonia-lyase
YPA_RS21445	COG4607	ABC-type enterochelin transport system periplasmic component
YPA_RS21455	COG4605	iron ion homeostasis
YPA_RS21460	COG4604	ABC transporter, ATP-binding protein
YPA_RS21500	COG0582	viral genome integration into host DNA
YPA_RS21505	COG1609	Transcriptional regulator
YPA_RS21505	COG2207	Transcriptional regulator
YPA_RS21510	COG4214	carbohydrate transport
YPA_RS21520	COG4213	ABC transporter substrate-binding protein
YPA_RS21530	COG1070	Carbohydrate kinase
YPA_RS21540	COG3121	Chaperone
YPA_RS21555	COG3274	enterobacterial common antigen metabolic process
YPA_RS21570	COG2801	Transposase and inactivated derivatives
YPA_RS21575	COG0561	phosphatase activity
YPA_RS21580	COG0187	DNA topoisomerase II activity
YPA_RS21590	COG0592	DNA-directed DNA polymerase activity
YPA_RS21600	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPA_RS21610	COG0706	membrane insertase activity
YPA_RS21635	COG2252	PERMEase
YPA_RS21640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPA_RS21645	COG0765	amino acid transport
YPA_RS21650	COG0765	amino acid transport
YPA_RS21655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPA_RS21665	COG0704	Plays a role in the regulation of phosphate uptake
YPA_RS21675	COG0581	inorganic phosphate transmembrane transporter activity
YPA_RS21680	COG0573	inorganic phosphate transmembrane transporter activity
YPA_RS21685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPA_RS21740	COG3312	ion transport
YPA_RS22435	COG0477	Major facilitator Superfamily