locus-tag	class	description
CH58_RS00070	COG1801	Protein of unknown function DUF72
CH58_RS00115	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH58_RS00135	COG1737	Transcriptional regulator
CH58_RS00370	COG3328	transposase activity
CH58_RS00635	COG0217	transcriptional regulatory protein
CH58_RS00705	COG0739	heme binding
CH58_RS00715	COG0469	pyruvate kinase activity
CH58_RS00800	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH58_RS01060	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH58_RS01065	COG1801	Protein of unknown function DUF72
CH58_RS01075	COG0494	nUDIX hydrolase
CH58_RS01105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH58_RS01115	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH58_RS01120	COG0739	heme binding
CH58_RS01125	COG1560	Kdo2-lipid A biosynthetic process
CH58_RS01130	COG0469	pyruvate kinase activity
CH58_RS01135	COG1737	Transcriptional regulator
CH58_RS01140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH58_RS01150	COG0800	Aldolase
CH58_RS01165	COG0251	oxidation-reduction process
CH58_RS01170	COG1199	ATP-dependent helicase activity
CH58_RS01180	COG3065	identical protein binding
CH58_RS01185	COG0318	PFAM AMP-dependent synthetase and ligase
CH58_RS01190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH58_RS01195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH58_RS01200	COG2894	cell division
CH58_RS01215	COG2951	lytic endotransglycosylase activity
CH58_RS01220	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH58_RS01230	COG0582	viral genome integration into host DNA
CH58_RS01410	COG3328	transposase activity
CH58_RS01420	COG1104	cysteine desulfurase activity
CH58_RS01450	COG2719	SpoVR family
CH58_RS01460	COG2814	Major facilitator Superfamily
CH58_RS01470	COG0583	DNA-binding transcription factor activity
CH58_RS01485	COG2766	serine protein kinase
CH58_RS01490	COG3713	MltA-interacting MipA family protein
CH58_RS01510	COG3139	Protein of unknown function (DUF1315)
CH58_RS01515	COG1335	isochorismatase
CH58_RS01520	COG0252	asparaginase activity
CH58_RS01525	COG0616	signal peptide processing
CH58_RS01530	COG0778	Nitroreductase
CH58_RS01535	COG0709	Synthesizes selenophosphate from selenide and ATP
CH58_RS01540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH58_RS01550	COG0494	nUDIX hydrolase
CH58_RS01555	COG0708	Exodeoxyribonuclease III
CH58_RS01560	COG0583	DNA-binding transcription factor activity
CH58_RS01570	COG3328	transposase activity
CH58_RS01575	COG0788	formyltetrahydrofolate deformylase activity
CH58_RS01585	COG0745	RESPONSE REGULATOR receiver
CH58_RS01625	COG1454	alcohol dehydrogenase
CH58_RS01625	COG1012	belongs to the aldehyde dehydrogenase family
CH58_RS01630	COG2095	MarC family integral membrane protein
CH58_RS01640	COG0601	transmembrane transport
CH58_RS01645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH58_RS01650	COG0444	Belongs to the ABC transporter superfamily
CH58_RS01655	COG4608	Belongs to the ABC transporter superfamily
CH58_RS01690	COG2350	Protein conserved in bacteria
CH58_RS01695	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH58_RS01700	COG3328	transposase activity
CH58_RS01735	COG3047	cAMP biosynthetic process
CH58_RS01755	COG0134	indole-3-glycerol-phosphate synthase activity
CH58_RS01755	COG0135	phosphoribosylanthranilate isomerase activity
CH58_RS01765	COG0512	Glutamine amidotransferase of anthranilate synthase
CH58_RS01790	COG0009	L-threonylcarbamoyladenylate synthase
CH58_RS01795	COG1187	pseudouridine synthase activity
CH58_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS01810	COG0616	signal peptide processing
CH58_RS01830	COG0583	DNA-binding transcription factor activity
CH58_RS01840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH58_RS01850	COG0671	phosphoesterase, PA-phosphatase related
CH58_RS01855	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH58_RS01860	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH58_RS01875	COG0023	Translation Initiation Factor
CH58_RS01895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH58_RS01900	COG2879	small protein
CH58_RS01905	COG1966	Carbon starvation protein
CH58_RS01915	COG2271	Major facilitator Superfamily
CH58_RS01920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH58_RS01925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH58_RS01935	COG4659	FMN binding
CH58_RS01940	COG4658	electron transport chain
CH58_RS01945	COG2207	Transcriptional regulator
CH58_RS01945	COG3708	Transcriptional regulator
CH58_RS01975	COG1132	(ABC) transporter
CH58_RS01985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH58_RS01990	COG2274	protein secretion by the type I secretion system
CH58_RS02005	COG1879	ABC-type sugar transport system periplasmic component
CH58_RS02010	COG1129	ABC transporter
CH58_RS02015	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS02025	COG0673	inositol 2-dehydrogenase activity
CH58_RS02030	COG0385	Bile acid
CH58_RS02040	COG5339	Protein conserved in bacteria
CH58_RS02050	COG0114	fumarate hydratase activity
CH58_RS02065	COG0583	DNA-binding transcription factor activity
CH58_RS02070	COG1940	carbohydrate kinase activity
CH58_RS02075	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH58_RS02085	COG1609	Transcriptional regulator
CH58_RS02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH58_RS02110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH58_RS02135	COG0028	Belongs to the TPP enzyme family
CH58_RS02140	COG0440	acetolactate synthase activity
CH58_RS02145	COG1011	Hydrolase
CH58_RS02165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH58_RS02170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH58_RS02175	COG0589	response to stress
CH58_RS02180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH58_RS02185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH58_RS02200	COG0531	amino acid
CH58_RS02210	COG0745	RESPONSE REGULATOR receiver
CH58_RS02215	COG2205	protein histidine kinase activity
CH58_RS02220	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH58_RS02255	COG3038	cytochrome b561
CH58_RS02270	COG3591	Belongs to the peptidase S1B family
CH58_RS02285	COG1643	Atp-dependent helicase
CH58_RS02305	COG1643	Atp-dependent helicase
CH58_RS02315	COG2390	Transcriptional regulator
CH58_RS02320	COG0246	Mannitol dehydrogenase
CH58_RS02325	COG3784	Protein of unknown function (DUF1318)
CH58_RS02335	COG2911	Protein conserved in bacteria
CH58_RS02340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH58_RS02345	COG3187	Heat shock protein
CH58_RS02350	COG3042	response to heat
CH58_RS02355	COG1285	pathogenesis
CH58_RS02365	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH58_RS02365	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH58_RS02365	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH58_RS02365	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH58_RS02375	COG0657	acetylesterase activity
CH58_RS02390	COG4166	transmembrane transport
CH58_RS02395	COG2866	Carboxypeptidase
CH58_RS02400	COG4948	Mandelate Racemase Muconate Lactonizing
CH58_RS02405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH58_RS02420	COG5642	Protein of unknown function (DUF2384)
CH58_RS02425	COG5654	RES domain protein
CH58_RS02435	COG3106	COG3106 Predicted ATPase
CH58_RS02445	COG1983	PspC domain protein
CH58_RS02455	COG1842	Phage shock protein A
CH58_RS02460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH58_RS02480	COG4166	transmembrane transport
CH58_RS02485	COG4168	peptide transport system, permease
CH58_RS02490	COG4171	peptide transport system, permease
CH58_RS02500	COG4172	Belongs to the ABC transporter superfamily
CH58_RS02505	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH58_RS02505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH58_RS02510	COG3104	oligopeptide transport
CH58_RS02525	COG0625	glutathione transferase activity
CH58_RS02545	COG3895	Periplasmic Protein
CH58_RS02555	COG3133	Outer membrane lipoprotein
CH58_RS02565	COG4989	oxidoreductase activity
CH58_RS02570	COG3313	Fe-S protein
CH58_RS02575	COG2194	sulfuric ester hydrolase activity
CH58_RS02580	COG1309	transcriptional regulator
CH58_RS02585	COG1902	pentaerythritol trinitrate reductase activity
CH58_RS02595	COG0346	lactoylglutathione lyase activity
CH58_RS02600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH58_RS02605	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH58_RS02615	COG0791	NLP P60 protein
CH58_RS02630	COG0583	DNA-binding transcription factor activity
CH58_RS02635	COG2814	Major facilitator Superfamily
CH58_RS02640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH58_RS02645	COG0307	riboflavin synthase, alpha
CH58_RS02695	COG1388	LysM domain
CH58_RS02695	COG1376	ErfK ybiS ycfS ynhG family protein
CH58_RS02710	COG0719	Fe-S assembly protein
CH58_RS02715	COG0396	ATPase activity
CH58_RS02720	COG0719	Fe-S assembly protein
CH58_RS02725	COG0316	Belongs to the HesB IscA family
CH58_RS02735	COG2050	protein possibly involved in aromatic compounds catabolism
CH58_RS02740	COG0247	lactate metabolic process
CH58_RS02740	COG0277	FAD linked oxidase domain protein
CH58_RS02745	COG0628	permease
CH58_RS02750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH58_RS02750	COG0574	Belongs to the PEP-utilizing enzyme family
CH58_RS02775	COG0791	NLP P60 protein
CH58_RS02820	COG0386	Belongs to the glutathione peroxidase family
CH58_RS02835	COG0776	regulation of translation
CH58_RS02840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH58_RS02840	COG0072	phenylalanine-tRNA ligase activity
CH58_RS02870	COG4249	Peptidase C14 caspase catalytic subunit p20
CH58_RS02895	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH58_RS02900	COG1121	(ABC) transporter
CH58_RS02905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH58_RS02910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH58_RS02920	COG3001	Fructosamine kinase
CH58_RS02930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH58_RS02940	COG1917	Cupin 2, conserved barrel domain protein
CH58_RS02950	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS02980	COG1175	transmembrane transport
CH58_RS02985	COG0395	ABC-type sugar transport system, permease component
CH58_RS02990	COG3842	ATPase activity
CH58_RS02995	COG1653	transport
CH58_RS03000	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH58_RS03005	COG1988	membrane-bound metal-dependent
CH58_RS03010	COG1823	symporter activity
CH58_RS03015	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH58_RS03025	COG0823	Involved in the tonB-independent uptake of proteins
CH58_RS03030	COG2814	Major facilitator Superfamily
CH58_RS03035	COG3121	Chaperone
CH58_RS03050	COG3121	Chaperone
CH58_RS03055	COG3539	Fimbrial protein
CH58_RS03065	COG0793	Belongs to the peptidase S41A family
CH58_RS03075	COG1956	GAF domain-containing protein
CH58_RS03080	COG2995	paraquat-inducible protein a
CH58_RS03085	COG3008	intermembrane lipid transfer
CH58_RS03105	COG3121	Chaperone
CH58_RS03160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH58_RS03170	COG5295	Hep Hag repeat protein
CH58_RS03180	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH58_RS03190	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH58_RS03195	COG0745	RESPONSE REGULATOR receiver
CH58_RS03205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH58_RS03210	COG0840	transmembrane signaling receptor activity
CH58_RS03215	COG0840	transmembrane signaling receptor activity
CH58_RS03235	COG2964	Protein conserved in bacteria
CH58_RS03245	COG0251	oxidation-reduction process
CH58_RS03250	COG2271	Major facilitator Superfamily
CH58_RS03255	COG0835	chemotaxis
CH58_RS03260	COG0643	Histidine kinase
CH58_RS03260	COG2198	Histidine kinase
CH58_RS03265	COG1360	Flagellar Motor Protein
CH58_RS03290	COG1285	pathogenesis
CH58_RS03335	COG3321	synthase
CH58_RS03335	COG0604	alcohol dehydrogenase
CH58_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS03345	COG1522	sequence-specific DNA binding
CH58_RS03370	COG1733	regulation of RNA biosynthetic process
CH58_RS03375	COG0702	epimerase
CH58_RS03380	COG0840	transmembrane signaling receptor activity
CH58_RS03395	COG0538	isocitrate dehydrogenase activity
CH58_RS03400	COG1187	pseudouridine synthase activity
CH58_RS03420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH58_RS03430	COG0745	RESPONSE REGULATOR receiver
CH58_RS03440	COG2850	peptidyl-arginine hydroxylation
CH58_RS03455	COG1940	carbohydrate kinase activity
CH58_RS03460	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH58_RS03470	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH58_RS03475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH58_RS03480	COG3134	Outer membrane lipoprotein
CH58_RS03485	COG3328	transposase activity
CH58_RS03500	COG1252	NADH dehydrogenase
CH58_RS03510	COG1472	Belongs to the glycosyl hydrolase 3 family
CH58_RS03525	COG5633	Lipoprotein
CH58_RS03530	COG0537	adenosine 5'-monophosphoramidase activity
CH58_RS03535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH58_RS03555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH58_RS03555	COG1263	PTS System
CH58_RS03560	COG0084	hydrolase, TatD family'
CH58_RS03565	COG0470	DNA polymerase III
CH58_RS03575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH58_RS03580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH58_RS03590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH58_RS03620	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH58_RS03625	COG1399	metal-binding, possibly nucleic acid-binding protein
CH58_RS03630	COG0424	maF-like protein
CH58_RS03645	COG0564	pseudouridine synthase activity
CH58_RS03650	COG1530	ribonuclease E activity
CH58_RS03660	COG3328	transposase activity
CH58_RS03665	COG3328	transposase activity
CH58_RS03670	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH58_RS03705	COG3328	transposase activity
CH58_RS03710	COG2197	response regulator
CH58_RS03715	COG0628	permease
CH58_RS03745	COG3916	Acyl-homoserine-lactone synthase
CH58_RS03750	COG2771	luxR family
CH58_RS03755	COG0583	DNA-binding transcription factor activity
CH58_RS03765	COG0477	Major facilitator Superfamily
CH58_RS03775	COG0667	Aldo Keto reductase
CH58_RS03800	COG1203	CRISPR-associated helicase, Cas3
CH58_RS03805	COG1518	maintenance of DNA repeat elements
CH58_RS03810	COG0668	transmembrane transport
CH58_RS03830	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH58_RS03835	COG0395	ABC-type sugar transport system, permease component
CH58_RS03850	COG1609	Transcriptional regulator
CH58_RS03860	COG3842	ATPase activity
CH58_RS03870	COG3210	domain, Protein
CH58_RS03890	COG3210	domain, Protein
CH58_RS03910	COG3210	domain, Protein
CH58_RS03915	COG2831	hemolysin activation secretion protein
CH58_RS03920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH58_RS03925	COG4638	Rieske (2fe-2S)
CH58_RS03930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH58_RS03940	COG0473	3-isopropylmalate dehydrogenase activity
CH58_RS03945	COG0583	DNA-binding transcription factor activity
CH58_RS03950	COG1609	Transcriptional regulator
CH58_RS03955	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS03960	COG1129	ABC transporter
CH58_RS03965	COG1879	ABC-type sugar transport system periplasmic component
CH58_RS03970	COG1063	alcohol dehydrogenase
CH58_RS04000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS04005	COG0765	amino acid transport
CH58_RS04010	COG1126	abc transporter atp-binding protein
CH58_RS04040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH58_RS04055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH58_RS04070	COG1169	isochorismate synthase
CH58_RS04080	COG4575	ribosome binding
CH58_RS04095	COG0129	dihydroxy-acid dehydratase activity
CH58_RS04110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH58_RS04120	COG1609	Transcriptional regulator
CH58_RS04125	COG1649	PFAM Uncharacterised BCR, COG1649
CH58_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS04135	COG3265	gluconokinase activity
CH58_RS04140	COG2731	YhcH YjgK YiaL family protein
CH58_RS04155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH58_RS04160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH58_RS04170	COG0839	Belongs to the complex I subunit 6 family
CH58_RS04185	COG1034	ATP synthesis coupled electron transport
CH58_RS04205	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH58_RS04215	COG0583	DNA-binding transcription factor activity
CH58_RS04225	COG0436	Aminotransferase
CH58_RS04240	COG0490	domain, Protein
CH58_RS04240	COG0471	metal ion transport
CH58_RS04245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH58_RS04270	COG0857	belongs to the CobB CobQ family
CH58_RS04270	COG0280	phosphate acetyltransferase
CH58_RS04275	COG1609	Transcriptional regulator
CH58_RS04290	COG3037	sugar-specific permease SgaT UlaA
CH58_RS04295	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH58_RS04300	COG0622	Phosphoesterase
CH58_RS04310	COG1090	epimerase
CH58_RS04315	COG4598	ABC transporter
CH58_RS04320	COG4160	amino acid transport
CH58_RS04325	COG4215	(ABC) transporter
CH58_RS04330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS04350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH58_RS04355	COG1286	toxin biosynthetic process
CH58_RS04360	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH58_RS04365	COG0285	dihydrofolate synthase activity
CH58_RS04375	COG0586	Pfam SNARE associated Golgi protein
CH58_RS04385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH58_RS04405	COG0697	spore germination
CH58_RS04420	COG1794	racemase activity, acting on amino acids and derivatives
CH58_RS04425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH58_RS04440	COG3101	peptidyl-lysine hydroxylation
CH58_RS04445	COG0730	response to heat
CH58_RS04460	COG2890	protein-(glutamine-N5) methyltransferase activity
CH58_RS04475	COG2062	phosphohistidine phosphatase, SixA
CH58_RS04490	COG3691	Protein conserved in bacteria
CH58_RS04505	COG3088	subunit of a heme lyase
CH58_RS04505	COG4235	cytochrome complex assembly
CH58_RS04510	COG3088	subunit of a heme lyase
CH58_RS04510	COG4235	cytochrome complex assembly
CH58_RS04515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH58_RS04520	COG1138	Cytochrome C-type biogenesis protein
CH58_RS04530	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH58_RS04535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH58_RS04540	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH58_RS04560	COG1704	LemA family
CH58_RS04570	COG2824	Alkylphosphonate utilization operon protein PhnA
CH58_RS04665	COG3188	usher protein
CH58_RS04675	COG3188	usher protein
CH58_RS04680	COG3121	Chaperone
CH58_RS04740	COG2951	lytic endotransglycosylase activity
CH58_RS04775	COG0243	molybdopterin cofactor binding
CH58_RS04780	COG0437	4 iron, 4 sulfur cluster binding
CH58_RS04785	COG3302	dmso reductase anchor subunit
CH58_RS04790	COG3381	protein complex oligomerization
CH58_RS04820	COG3038	cytochrome b561
CH58_RS04825	COG0436	Aminotransferase
CH58_RS04850	COG0667	Aldo Keto reductase
CH58_RS04865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH58_RS04915	COG3530	Putative quorum-sensing-regulated virulence factor
CH58_RS04930	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH58_RS04940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS04965	COG2205	protein histidine kinase activity
CH58_RS04970	COG0745	RESPONSE REGULATOR receiver
CH58_RS04975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH58_RS04990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH58_RS05010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH58_RS05020	COG3850	Histidine kinase
CH58_RS05020	COG5002	protein histidine kinase activity
CH58_RS05025	COG0745	RESPONSE REGULATOR receiver
CH58_RS05040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH58_RS05045	COG4208	sulfate ABC transporter
CH58_RS05050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH58_RS05055	COG4150	thiosulfate binding
CH58_RS05065	COG1737	Transcriptional regulator
CH58_RS05075	COG2731	YhcH YjgK YiaL family protein
CH58_RS05085	COG4886	Leucine-rich repeat (LRR) protein
CH58_RS05095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH58_RS05100	COG2837	iron assimilation
CH58_RS05110	COG3111	PFAM Bacterial OB fold (BOF) protein
CH58_RS05175	COG3005	denitrification pathway
CH58_RS05180	COG3043	anaerobic respiration
CH58_RS05190	COG3062	negative regulation of establishment of protein localization
CH58_RS05195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH58_RS05195	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH58_RS05200	COG2197	response regulator
CH58_RS05210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH58_RS05220	COG1988	membrane-bound metal-dependent
CH58_RS05225	COG0641	radical SAM
CH58_RS05230	COG3119	arylsulfatase activity
CH58_RS05235	COG3842	ATPase activity
CH58_RS05240	COG1175	transmembrane transport
CH58_RS05255	COG1393	Belongs to the ArsC family
CH58_RS05265	COG1876	peptidase activity
CH58_RS05285	COG2321	neutral zinc metallopeptidase
CH58_RS05305	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH58_RS05315	COG2716	regulation of RNA biosynthetic process
CH58_RS05320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH58_RS05340	COG0628	permease
CH58_RS05345	COG4783	chaperone-mediated protein folding
CH58_RS05350	COG1393	Belongs to the ArsC family
CH58_RS05375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH58_RS05380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH58_RS05400	COG0581	inorganic phosphate transmembrane transporter activity
CH58_RS05410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH58_RS05425	COG2239	Acts as a magnesium transporter
CH58_RS05430	COG0443	Heat shock 70 kDa protein
CH58_RS05445	COG1177	transmembrane transport
CH58_RS05450	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH58_RS05460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH58_RS05470	COG3842	ATPase activity
CH58_RS05495	COG2205	protein histidine kinase activity
CH58_RS05500	COG2205	protein histidine kinase activity
CH58_RS05505	COG0745	RESPONSE REGULATOR receiver
CH58_RS05510	COG3422	double-strand break repair
CH58_RS05515	COG0826	peptidase U32
CH58_RS05535	COG0351	phosphomethylpyrimidine kinase
CH58_RS05550	COG3328	transposase activity
CH58_RS05605	COG0516	GMP reductase activity
CH58_RS05605	COG0517	IMP dehydrogenase activity
CH58_RS05615	COG1645	bacterial-type flagellum-dependent swarming motility
CH58_RS05630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH58_RS05635	COG2976	Protein conserved in bacteria
CH58_RS05680	COG3468	outer membrane autotransporter barrel domain protein
CH58_RS05685	COG3468	outer membrane autotransporter barrel domain protein
CH58_RS05705	COG2975	iron-sulfur cluster assembly
CH58_RS05710	COG0633	Ferredoxin
CH58_RS05715	COG0443	Heat shock 70 kDa protein
CH58_RS05730	COG0822	iron-sulfur transferase activity
CH58_RS05735	COG1104	cysteine desulfurase activity
CH58_RS05755	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH58_RS05760	COG3683	transport system, periplasmic component
CH58_RS05765	COG3711	transcriptional antiterminator
CH58_RS05770	COG2814	Major facilitator Superfamily
CH58_RS05790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH58_RS05790	COG1017	nitric oxide dioxygenase activity
CH58_RS05795	COG2188	Transcriptional regulator
CH58_RS05800	COG2188	Transcriptional regulator
CH58_RS05805	COG0347	Belongs to the P(II) protein family
CH58_RS05810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH58_RS05810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH58_RS05815	COG2204	response regulator
CH58_RS05820	COG3170	Tfp pilus assembly protein FimV
CH58_RS05825	COG2205	protein histidine kinase activity
CH58_RS05865	COG0560	Phosphoserine phosphatase
CH58_RS05875	COG1737	Transcriptional regulator
CH58_RS05880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH58_RS05900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH58_RS05920	COG2113	Glycine betaine
CH58_RS05925	COG4176	ABC-type proline glycine betaine transport system permease component
CH58_RS05930	COG4175	Glycine betaine
CH58_RS05935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH58_RS05965	COG3328	transposase activity
CH58_RS05985	COG1278	Cold shock
CH58_RS05990	COG0747	negative chemotaxis
CH58_RS06000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH58_RS06005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH58_RS06010	COG1124	(ABC) transporter
CH58_RS06015	COG0831	urea catabolic process
CH58_RS06040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH58_RS06050	COG4413	Urea transporter
CH58_RS06055	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH58_RS06070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH58_RS06080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH58_RS06090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH58_RS06095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH58_RS06100	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH58_RS06105	COG2169	Transcriptional regulator
CH58_RS06105	COG1917	Cupin 2, conserved barrel domain protein
CH58_RS06125	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH58_RS06130	COG0033	Phosphoglucomutase
CH58_RS06150	COG0745	RESPONSE REGULATOR receiver
CH58_RS06155	COG2205	protein histidine kinase activity
CH58_RS06190	COG3272	Protein of unknown function (DUF1722)
CH58_RS06200	COG5212	phosphodiesterase
CH58_RS06205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH58_RS06215	COG1984	allophanate hydrolase subunit 2
CH58_RS06265	COG0513	Belongs to the DEAD box helicase family
CH58_RS06275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH58_RS06290	COG3026	antisigma factor binding
CH58_RS06295	COG3086	response to oxidative stress
CH58_RS06340	COG0582	viral genome integration into host DNA
CH58_RS06345	COG2963	transposase activity
CH58_RS06350	COG0582	viral genome integration into host DNA
CH58_RS06360	COG0596	Alpha beta hydrolase
CH58_RS06380	COG0735	belongs to the Fur family
CH58_RS06405	COG2190	(PTS) system
CH58_RS06405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH58_RS06405	COG1263	PTS System
CH58_RS06415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH58_RS06420	COG1940	carbohydrate kinase activity
CH58_RS06420	COG1846	Transcriptional regulator
CH58_RS06425	COG0647	UMP catabolic process
CH58_RS06430	COG0367	asparagine synthase
CH58_RS06470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH58_RS06475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH58_RS06480	COG1702	phosphate starvation-inducible protein PhoH
CH58_RS06490	COG4535	Mg2 and Co2 transporter CorC
CH58_RS06495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH58_RS06505	COG0765	amino acid transport
CH58_RS06510	COG0765	amino acid transport
CH58_RS06515	COG1126	abc transporter atp-binding protein
CH58_RS06520	COG2888	peptidyl-tyrosine sulfation
CH58_RS06535	COG1466	dna polymerase III delta subunit
CH58_RS06545	COG0799	negative regulation of ribosome biogenesis
CH58_RS06555	COG0768	penicillin binding
CH58_RS06560	COG0772	Belongs to the SEDS family
CH58_RS06565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH58_RS06580	COG1686	Belongs to the peptidase S11 family
CH58_RS06600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH58_RS06610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH58_RS06620	COG1278	Cold shock
CH58_RS06625	COG2197	response regulator
CH58_RS06650	COG5265	(ABC) transporter
CH58_RS06660	COG3718	enzyme involved in inositol metabolism
CH58_RS06675	COG0673	inositol 2-dehydrogenase activity
CH58_RS06680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS06685	COG1129	ABC transporter
CH58_RS06700	COG3962	Belongs to the TPP enzyme family
CH58_RS06725	COG2373	Large extracellular alpha-helical protein
CH58_RS06730	COG4953	penicillin-binding protein 1C
CH58_RS06735	COG3328	transposase activity
CH58_RS06740	COG4953	penicillin-binding protein 1C
CH58_RS06745	COG3423	Transcriptional regulator
CH58_RS06795	COG2850	peptidyl-arginine hydroxylation
CH58_RS06815	COG1472	Belongs to the glycosyl hydrolase 3 family
CH58_RS06835	COG0656	L-ascorbic acid biosynthetic process
CH58_RS06840	COG0667	Aldo Keto reductase
CH58_RS06875	COG0671	phosphoesterase, PA-phosphatase related
CH58_RS06875	COG2453	phosphatase
CH58_RS06880	COG2267	carboxylic ester hydrolase activity
CH58_RS06890	COG4589	Belongs to the CDS family
CH58_RS06895	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH58_RS06945	COG2501	S4 domain
CH58_RS06965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH58_RS06975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH58_RS06980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH58_RS06985	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH58_RS06990	COG4181	ATPase activity
CH58_RS06995	COG2755	lipolytic protein G-D-S-L family
CH58_RS07000	COG0300	oxidoreductase activity
CH58_RS07005	COG3118	belongs to the thioredoxin family
CH58_RS07010	COG0330	HflC and HflK could
CH58_RS07015	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH58_RS07020	COG0789	Transcriptional regulator
CH58_RS07025	COG2217	Heavy metal translocating P-type atpase
CH58_RS07030	COG3735	TraB family
CH58_RS07035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH58_RS07050	COG0737	Belongs to the 5'-nucleotidase family
CH58_RS07055	COG0737	Belongs to the 5'-nucleotidase family
CH58_RS07060	COG0737	Belongs to the 5'-nucleotidase family
CH58_RS07065	COG2223	nitrite transmembrane transporter activity
CH58_RS07070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH58_RS07070	COG4651	solute:proton antiporter activity
CH58_RS07075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH58_RS07080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH58_RS07100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH58_RS07140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH58_RS07165	COG0543	2 iron, 2 sulfur cluster binding
CH58_RS07165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH58_RS07195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH58_RS07220	COG1196	nuclear chromosome segregation
CH58_RS07220	COG3264	Mechanosensitive ion channel
CH58_RS07235	COG3264	Mechanosensitive ion channel
CH58_RS07235	COG1196	nuclear chromosome segregation
CH58_RS07240	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH58_RS07245	COG1309	transcriptional regulator
CH58_RS07250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH58_RS07255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH58_RS07265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH58_RS07285	COG3695	enzyme binding
CH58_RS07290	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH58_RS07295	COG1946	Acyl-CoA thioesterase
CH58_RS07300	COG0004	ammonium transporteR
CH58_RS07305	COG0347	Belongs to the P(II) protein family
CH58_RS07310	COG1132	(ABC) transporter
CH58_RS07315	COG1132	(ABC) transporter
CH58_RS07320	COG1522	sequence-specific DNA binding
CH58_RS07335	COG4533	DNA binding
CH58_RS07345	COG0824	Thioesterase
CH58_RS07350	COG1555	photosystem II stabilization
CH58_RS07355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH58_RS07360	COG0776	regulation of translation
CH58_RS07365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH58_RS07390	COG0271	Belongs to the BolA IbaG family
CH58_RS07395	COG3056	Lipoprotein
CH58_RS07400	COG2223	nitrite transmembrane transporter activity
CH58_RS07410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH58_RS07415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH58_RS07420	COG1845	cytochrome c oxidase, subunit III
CH58_RS07425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH58_RS07435	COG2814	Major facilitator Superfamily
CH58_RS07445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH58_RS07450	COG0693	protein deglycase activity
CH58_RS07470	COG0142	geranyltranstransferase activity
CH58_RS07490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH58_RS07495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH58_RS07510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH58_RS07510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH58_RS07545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH58_RS07550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH58_RS07555	COG1862	Preprotein translocase
CH58_RS07575	COG0450	alkyl hydroperoxide reductase
CH58_RS07600	COG0366	Alpha amylase catalytic
CH58_RS07620	COG5002	protein histidine kinase activity
CH58_RS07625	COG0745	RESPONSE REGULATOR receiver
CH58_RS07635	COG0420	3'-5' exonuclease activity
CH58_RS07640	COG0419	ATPase involved in DNA repair
CH58_RS07660	COG0419	ATPase involved in DNA repair
CH58_RS07665	COG1940	carbohydrate kinase activity
CH58_RS07700	COG2226	methyltransferase
CH58_RS07760	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH58_RS07780	COG1477	protein flavinylation
CH58_RS07800	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH58_RS07805	COG1805	sodium ion transport
CH58_RS07815	COG3034	peptidoglycan biosynthetic process
CH58_RS07820	COG0121	glutamine amidotransferase
CH58_RS07830	COG1960	acyl-CoA dehydrogenase activity
CH58_RS07840	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH58_RS07860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH58_RS07875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH58_RS07885	COG0765	amino acid transport
CH58_RS07925	COG2814	Major facilitator Superfamily
CH58_RS07930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH58_RS07940	COG1846	Transcriptional regulator
CH58_RS07945	COG1566	PFAM secretion protein HlyD family protein
CH58_RS07950	COG2814	Major facilitator Superfamily
CH58_RS07955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH58_RS07960	COG3118	belongs to the thioredoxin family
CH58_RS07965	COG3148	PFAM DTW domain containing protein
CH58_RS07970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH58_RS07970	COG0045	succinate-CoA ligase (ADP-forming) activity
CH58_RS07970	COG1042	CoA-binding domain protein
CH58_RS07975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH58_RS07980	COG5544	Lipoprotein
CH58_RS08020	COG0542	response to heat
CH58_RS08030	COG0564	pseudouridine synthase activity
CH58_RS08035	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH58_RS08040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH58_RS08065	COG0077	Prephenate dehydratase
CH58_RS08065	COG1605	Chorismate mutase
CH58_RS08100	COG0529	Catalyzes the synthesis of activated sulfate
CH58_RS08140	COG4942	peptidase
CH58_RS08140	COG1388	LysM domain
CH58_RS08145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH58_RS08160	COG0698	ribose 5-phosphate isomerase
CH58_RS08165	COG1063	alcohol dehydrogenase
CH58_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS08175	COG2376	Dihydroxyacetone kinase
CH58_RS08190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH58_RS08210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS08215	COG1858	cytochrome C peroxidase
CH58_RS08225	COG4771	TonB-dependent receptor
CH58_RS08245	COG0024	Methionine aminopeptidase
CH58_RS08255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH58_RS08255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH58_RS08260	COG1070	Carbohydrate kinase
CH58_RS08265	COG3623	hexulose-6-phosphate isomerase
CH58_RS08270	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS08275	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS08280	COG1129	ABC transporter
CH58_RS08295	COG1349	DNA-binding transcription factor activity
CH58_RS08300	COG0235	Class ii aldolase
CH58_RS08305	COG0243	molybdopterin cofactor binding
CH58_RS08310	COG0437	4 iron, 4 sulfur cluster binding
CH58_RS08315	COG3302	dmso reductase anchor subunit
CH58_RS08320	COG3381	protein complex oligomerization
CH58_RS08325	COG3038	cytochrome b561
CH58_RS08330	COG3783	Cytochrome b(562)
CH58_RS08340	COG1879	ABC-type sugar transport system periplasmic component
CH58_RS08350	COG1129	ABC transporter
CH58_RS08355	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS08360	COG3959	Transketolase, thiamine diphosphate binding domain
CH58_RS08365	COG3958	Transketolase
CH58_RS08370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH58_RS08410	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH58_RS08435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH58_RS08440	COG1238	metal cluster binding
CH58_RS08445	COG2918	glutathione biosynthetic process
CH58_RS08465	COG4536	flavin adenine dinucleotide binding
CH58_RS08470	COG4137	Cytochrome C assembly protein
CH58_RS08475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH58_RS08510	COG3137	Salt-induced outer membrane protein
CH58_RS08515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH58_RS08520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH58_RS08525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH58_RS08530	COG3279	Response regulator of the LytR AlgR family
CH58_RS08535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH58_RS08540	COG1605	Chorismate mutase
CH58_RS08540	COG0287	Prephenate dehydrogenase
CH58_RS08545	COG0077	Prephenate dehydratase
CH58_RS08545	COG1605	Chorismate mutase
CH58_RS08605	COG0720	synthase
CH58_RS08610	COG0602	queuosine metabolic process
CH58_RS08630	COG3956	TIGRFAM MazG family protein
CH58_RS08640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH58_RS08645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CH58_RS08650	COG2205	protein histidine kinase activity
CH58_RS08650	COG3437	response regulator, receiver
CH58_RS08650	COG4999	Histidine kinase
CH58_RS08650	COG3850	Histidine kinase
CH58_RS08655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH58_RS08675	COG2860	membrane
CH58_RS08695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH58_RS08700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH58_RS08710	COG1120	ATPase activity
CH58_RS08715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH58_RS08720	COG1643	Atp-dependent helicase
CH58_RS08725	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH58_RS08740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH58_RS08745	COG0617	tRNA 3'-terminal CCA addition
CH58_RS08750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH58_RS08775	COG0842	Transport permease protein
CH58_RS08780	COG1131	(ABC) transporter
CH58_RS08785	COG0288	reversible hydration of carbon dioxide
CH58_RS08790	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH58_RS08795	COG2132	Multicopper oxidase
CH58_RS08815	COG0697	spore germination
CH58_RS08825	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH58_RS08840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH58_RS08845	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH58_RS08850	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH58_RS08855	COG2186	Transcriptional regulator
CH58_RS08860	COG1113	amino acid transport
CH58_RS08865	COG3725	Membrane protein required for beta-lactamase induction
CH58_RS08870	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH58_RS08880	COG4969	Belongs to the N-Me-Phe pilin family
CH58_RS08885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH58_RS08890	COG1459	type II secretion system
CH58_RS08945	COG0582	viral genome integration into host DNA
CH58_RS08955	COG0795	lipopolysaccharide-transporting ATPase activity
CH58_RS08960	COG0795	lipopolysaccharide-transporting ATPase activity
CH58_RS08970	COG2927	DNA polymerase III (CHI subunit)
CH58_RS08975	COG0525	valine-tRNA ligase activity
CH58_RS08985	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH58_RS08995	COG2731	YhcH YjgK YiaL family protein
CH58_RS09005	COG0601	transmembrane transport
CH58_RS09010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH58_RS09015	COG0444	Belongs to the ABC transporter superfamily
CH58_RS09020	COG4608	Belongs to the ABC transporter superfamily
CH58_RS09035	COG2188	Transcriptional regulator
CH58_RS09040	COG3624	Phosphonate C-P lyase system protein PhnG
CH58_RS09045	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH58_RS09050	COG3626	phosphonate metabolism
CH58_RS09055	COG3627	carbon phosphorus lyase activity
CH58_RS09060	COG4107	phosphonate C-P lyase system protein PhnK
CH58_RS09065	COG4778	phosphonate C-P lyase system protein PhnL
CH58_RS09070	COG3454	Phosphonate metabolism
CH58_RS09075	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH58_RS09080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH58_RS09085	COG0702	epimerase
CH58_RS09100	COG3842	ATPase activity
CH58_RS09105	COG0395	ABC-type sugar transport system, permease component
CH58_RS09110	COG1175	transmembrane transport
CH58_RS09115	COG1653	transport
CH58_RS09135	COG3153	acetyltransferase
CH58_RS09140	COG3154	lipid carrier protein
CH58_RS09150	COG0826	peptidase U32
CH58_RS09155	COG0826	peptidase U32
CH58_RS09165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH58_RS09175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH58_RS09195	COG0513	Belongs to the DEAD box helicase family
CH58_RS09210	COG2801	Transposase and inactivated derivatives
CH58_RS09220	COG2423	ornithine cyclodeaminase activity
CH58_RS09225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH58_RS09230	COG0823	Involved in the tonB-independent uptake of proteins
CH58_RS09235	COG0823	Involved in the tonB-independent uptake of proteins
CH58_RS09240	COG5645	(Lipo)protein
CH58_RS09260	COG3977	Valine--pyruvate aminotransferase
CH58_RS09270	COG0366	Alpha amylase catalytic
CH58_RS09285	COG2885	chlorophyll binding
CH58_RS09295	COG2818	Glycosylase
CH58_RS09315	COG2213	PTS system mannitol-specific
CH58_RS09315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS09325	COG3722	fumarate hydratase activity
CH58_RS09365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH58_RS09375	COG3383	formate dehydrogenase (NAD+) activity
CH58_RS09375	COG0243	molybdopterin cofactor binding
CH58_RS09380	COG0243	molybdopterin cofactor binding
CH58_RS09380	COG3383	formate dehydrogenase (NAD+) activity
CH58_RS09385	COG0437	4 iron, 4 sulfur cluster binding
CH58_RS09390	COG2864	formate dehydrogenase
CH58_RS09405	COG3276	selenocysteine insertion sequence binding
CH58_RS09440	COG2801	Transposase and inactivated derivatives
CH58_RS09485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH58_RS09490	COG1191	sigma factor activity
CH58_RS09515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH58_RS09535	COG3710	Transcriptional regulator
CH58_RS09555	COG1256	bacterial-type flagellum assembly
CH58_RS09565	COG1706	bacterial-type flagellum-dependent cell motility
CH58_RS09575	COG4786	Flagellar basal body rod
CH58_RS09580	COG4787	bacterial-type flagellum-dependent cell motility
CH58_RS09585	COG1749	Flagellar hook protein flgE
CH58_RS09590	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH58_RS09595	COG1558	bacterial-type flagellum-dependent cell motility
CH58_RS09600	COG1815	bacterial-type flagellum-dependent cell motility
CH58_RS09605	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH58_RS09665	COG1677	Flagellar hook-basal body complex protein FliE
CH58_RS09690	COG1987	bacterial-type flagellum assembly
CH58_RS09695	COG1684	flagellar biosynthetic protein fliR
CH58_RS09700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH58_RS09720	COG4592	Periplasmic binding protein
CH58_RS09755	COG4964	Belongs to the GSP D family
CH58_RS09760	COG4964	Belongs to the GSP D family
CH58_RS09810	COG0848	biopolymer transport protein
CH58_RS09815	COG0811	peptide transport
CH58_RS09820	COG0626	cystathionine gamma-synthase activity
CH58_RS09830	COG2207	Transcriptional regulator
CH58_RS09835	COG1979	alcohol dehydrogenase
CH58_RS09845	COG0656	L-ascorbic acid biosynthetic process
CH58_RS09855	COG2132	Multicopper oxidase
CH58_RS09865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH58_RS09875	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH58_RS09880	COG0583	DNA-binding transcription factor activity
CH58_RS09890	COG3150	esterase
CH58_RS09900	COG3151	Protein conserved in bacteria
CH58_RS09905	COG0494	nUDIX hydrolase
CH58_RS09910	COG1538	Outer membrane efflux protein
CH58_RS09925	COG0754	glutathionylspermidine amidase activity
CH58_RS09930	COG3384	dioxygenase
CH58_RS09950	COG0531	amino acid
CH58_RS09965	COG3025	triphosphatase activity
CH58_RS09970	COG4991	sh3 domain protein
CH58_RS09985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH58_RS10000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH58_RS10005	COG0358	DNA primase activity
CH58_RS10105	COG0251	oxidation-reduction process
CH58_RS10125	COG0436	Aminotransferase
CH58_RS10150	COG1289	transmembrane transporter activity
CH58_RS10170	COG0395	ABC-type sugar transport system, permease component
CH58_RS10180	COG2182	Extracellular solute-binding protein
CH58_RS10185	COG1609	Transcriptional regulator
CH58_RS10190	COG3459	Glycosyltransferase 36 associated
CH58_RS10195	COG3842	ATPase activity
CH58_RS10215	COG3210	domain, Protein
CH58_RS10240	COG3210	domain, Protein
CH58_RS10245	COG2831	hemolysin activation secretion protein
CH58_RS10250	COG4245	von Willebrand factor, type A
CH58_RS10265	COG4245	von Willebrand factor, type A
CH58_RS10285	COG3247	response to pH
CH58_RS10290	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH58_RS10290	COG1902	pentaerythritol trinitrate reductase activity
CH58_RS10305	COG1451	nucleotide metabolic process
CH58_RS10310	COG0673	inositol 2-dehydrogenase activity
CH58_RS10335	COG2721	sulfolactate sulfo-lyase activity
CH58_RS10355	COG2271	Major facilitator Superfamily
CH58_RS10370	COG0586	Pfam SNARE associated Golgi protein
CH58_RS10390	COG4575	ribosome binding
CH58_RS10395	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH58_RS10405	COG2259	Doxx family
CH58_RS10410	COG0435	Glutathione S-transferase
CH58_RS10435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH58_RS10450	COG0551	DNA topoisomerase type I activity
CH58_RS10460	COG0758	DNA mediated transformation
CH58_RS10490	COG3036	rescue of stalled ribosome
CH58_RS10495	COG0789	Transcriptional regulator
CH58_RS10510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH58_RS10525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH58_RS10530	COG0201	protein transport
CH58_RS10540	COG1841	ribosomal large subunit assembly
CH58_RS10580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH58_RS10585	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH58_RS10595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH58_RS10610	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH58_RS10620	COG0089	rRNA binding
CH58_RS10635	COG0051	transcription antitermination factor activity, RNA binding
CH58_RS10675	COG0049	tRNA binding
CH58_RS10680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH58_RS10700	COG2964	Protein conserved in bacteria
CH58_RS10705	COG0545	Peptidyl-prolyl cis-trans isomerase
CH58_RS10715	COG1047	Peptidyl-prolyl cis-trans
CH58_RS10720	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH58_RS10740	COG1216	Glycosyl transferase, family 2
CH58_RS10750	COG2175	clavaminate synthase activity
CH58_RS10755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH58_RS10765	COG4521	taurine ABC transporter
CH58_RS10775	COG0429	hydrolase of the alpha beta-hydrolase fold
CH58_RS10785	COG3954	Phosphoribulokinase
CH58_RS10795	COG1765	OsmC-like protein
CH58_RS10805	COG1289	transmembrane transporter activity
CH58_RS10820	COG0433	COG0433 Predicted ATPase
CH58_RS10825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH58_RS10830	COG1486	melibiose metabolic process
CH58_RS10850	COG0402	S-adenosylhomocysteine deaminase activity
CH58_RS10855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH58_RS10875	COG0180	Tryptophanyl-tRNA synthetase
CH58_RS10880	COG0546	phosphoglycolate phosphatase activity
CH58_RS10885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH58_RS10910	COG4796	Type ii and iii secretion system protein
CH58_RS10940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH58_RS10945	COG0494	nUDIX hydrolase
CH58_RS10960	COG1011	Hydrolase
CH58_RS10965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH58_RS10990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH58_RS10995	COG2183	response to ionizing radiation
CH58_RS11005	COG1918	ferrous iron import across plasma membrane
CH58_RS11040	COG1640	4-alpha-glucanotransferase
CH58_RS11045	COG0058	SHG alpha-glucan phosphorylase activity
CH58_RS11050	COG0058	SHG alpha-glucan phosphorylase activity
CH58_RS11070	COG1349	DNA-binding transcription factor activity
CH58_RS11090	COG2801	Transposase and inactivated derivatives
CH58_RS11095	COG5001	Diguanylate cyclase
CH58_RS11105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH58_RS11155	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH58_RS11160	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH58_RS11165	COG4771	TonB-dependent receptor
CH58_RS11195	COG2226	methyltransferase
CH58_RS11195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH58_RS11195	COG3433	isochorismatase activity
CH58_RS11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH58_RS11205	COG2226	methyltransferase
CH58_RS11205	COG3433	isochorismatase activity
CH58_RS11235	COG1132	(ABC) transporter
CH58_RS11250	COG2610	gluconate transmembrane transporter activity
CH58_RS11270	COG3501	Rhs element vgr protein
CH58_RS11280	COG3209	COG3209 Rhs family protein
CH58_RS11295	COG0471	metal ion transport
CH58_RS11310	COG2801	Transposase and inactivated derivatives
CH58_RS11385	COG3501	Rhs element vgr protein
CH58_RS11430	COG3501	Rhs element vgr protein
CH58_RS11440	COG3209	COG3209 Rhs family protein
CH58_RS11490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH58_RS11525	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH58_RS11530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH58_RS11535	COG1739	Uncharacterized protein family UPF0029
CH58_RS11545	COG1739	Uncharacterized protein family UPF0029
CH58_RS11570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH58_RS11640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH58_RS11645	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH58_RS11650	COG1494	fructose-1,6-bisphosphatase
CH58_RS11660	COG3152	Membrane
CH58_RS11675	COG0583	DNA-binding transcription factor activity
CH58_RS11680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH58_RS11685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH58_RS11690	COG0471	metal ion transport
CH58_RS11700	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH58_RS11720	COG3678	ATP-independent chaperone mediated protein folding
CH58_RS11725	COG0745	RESPONSE REGULATOR receiver
CH58_RS11730	COG2205	protein histidine kinase activity
CH58_RS11735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH58_RS11735	COG2169	Transcriptional regulator
CH58_RS11740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH58_RS11745	COG1045	serine acetyltransferase
CH58_RS11765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH58_RS11770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH58_RS11780	COG4942	peptidase
CH58_RS11795	COG0156	8-amino-7-oxononanoate synthase activity
CH58_RS11805	COG0859	PFAM glycosyl transferase family 9
CH58_RS11810	COG0859	PFAM glycosyl transferase family 9
CH58_RS11815	COG1519	Transferase
CH58_RS11850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH58_RS11875	COG1561	YicC-like family, N-terminal region
CH58_RS11880	COG2860	membrane
CH58_RS11900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH58_RS11905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH58_RS11910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH58_RS11915	COG0786	glutamate:sodium symporter activity
CH58_RS11920	COG2233	PERMEase
CH58_RS11925	COG2982	Protein involved in outer membrane biogenesis
CH58_RS11930	COG0456	acetyltransferase
CH58_RS11960	COG1011	Hydrolase
CH58_RS11975	COG0174	glutamine synthetase
CH58_RS11990	COG3852	Histidine kinase
CH58_RS12000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH58_RS12025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH58_RS12025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH58_RS12030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH58_RS12035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH58_RS12040	COG3084	Protein conserved in bacteria
CH58_RS12050	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH58_RS12055	COG3328	transposase activity
CH58_RS12085	COG2186	Transcriptional regulator
CH58_RS12090	COG0477	Major facilitator Superfamily
CH58_RS12100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH58_RS12145	COG1522	sequence-specific DNA binding
CH58_RS12150	COG0716	FMN binding
CH58_RS12165	COG3312	ion transport
CH58_RS12220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH58_RS12225	COG0573	inorganic phosphate transmembrane transporter activity
CH58_RS12230	COG0581	inorganic phosphate transmembrane transporter activity
CH58_RS12240	COG0704	Plays a role in the regulation of phosphate uptake
CH58_RS12250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS12255	COG0765	amino acid transport
CH58_RS12260	COG0765	amino acid transport
CH58_RS12265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH58_RS12270	COG2252	PERMEase
CH58_RS12295	COG0706	membrane insertase activity
CH58_RS12305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH58_RS12315	COG0592	DNA-directed DNA polymerase activity
CH58_RS12330	COG0187	DNA topoisomerase II activity
CH58_RS12335	COG0561	phosphatase activity
CH58_RS12340	COG2801	Transposase and inactivated derivatives
CH58_RS12355	COG3274	enterobacterial common antigen metabolic process
CH58_RS12380	COG3121	Chaperone
CH58_RS12390	COG1070	Carbohydrate kinase
CH58_RS12400	COG4213	ABC transporter substrate-binding protein
CH58_RS12410	COG4214	carbohydrate transport
CH58_RS12415	COG1609	Transcriptional regulator
CH58_RS12415	COG2207	Transcriptional regulator
CH58_RS12420	COG0582	viral genome integration into host DNA
CH58_RS12460	COG4604	ABC transporter, ATP-binding protein
CH58_RS12465	COG4605	iron ion homeostasis
CH58_RS12475	COG4607	ABC-type enterochelin transport system periplasmic component
CH58_RS12520	COG2986	histidine ammonia-lyase
CH58_RS12540	COG2197	response regulator
CH58_RS12545	COG3851	Histidine kinase
CH58_RS12585	COG0564	pseudouridine synthase activity
CH58_RS12590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH58_RS12645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH58_RS12655	COG2966	Psort location CytoplasmicMembrane, score
CH58_RS12660	COG1280	lysine exporter protein (LysE YggA)
CH58_RS12665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH58_RS12700	COG1047	Peptidyl-prolyl cis-trans
CH58_RS12715	COG0196	riboflavin kinase activity
CH58_RS12730	COG0583	DNA-binding transcription factor activity
CH58_RS12750	COG1584	GPR1 FUN34 yaaH family protein
CH58_RS12765	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH58_RS12795	COG0745	RESPONSE REGULATOR receiver
CH58_RS12800	COG3045	CreA protein
CH58_RS12805	COG2207	Transcriptional regulator
CH58_RS12805	COG3708	Transcriptional regulator
CH58_RS12820	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH58_RS12825	COG0741	lytic transglycosylase activity
CH58_RS12840	COG2199	diguanylate cyclase activity
CH58_RS12845	COG2885	chlorophyll binding
CH58_RS12880	COG3162	membrane
CH58_RS12890	COG1301	dicarboxylic acid transport
CH58_RS13000	COG2391	methyltransferase activity
CH58_RS13005	COG0425	Belongs to the sulfur carrier protein TusA family
CH58_RS13010	COG0583	DNA-binding transcription factor activity
CH58_RS13015	COG0814	amino acid
CH58_RS13020	COG0626	cystathionine gamma-synthase activity
CH58_RS13030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH58_RS13035	COG4558	Periplasmic binding protein
CH58_RS13040	COG3720	iron ion transport
CH58_RS13045	COG4771	TonB-dependent receptor
CH58_RS13050	COG0702	epimerase
CH58_RS13055	COG3721	Heme iron utilization protein
CH58_RS13080	COG1358	cellular component organization or biogenesis
CH58_RS13140	COG3121	Chaperone
CH58_RS13185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH58_RS13195	COG0735	belongs to the Fur family
CH58_RS13200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH58_RS13225	COG1448	Aminotransferase
CH58_RS13230	COG2315	Protein conserved in bacteria
CH58_RS13235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH58_RS13250	COG1454	alcohol dehydrogenase
CH58_RS13265	COG1454	alcohol dehydrogenase
CH58_RS13335	COG1309	transcriptional regulator
CH58_RS13340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH58_RS13340	COG0493	'glutamate synthase
CH58_RS13345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH58_RS13350	COG3383	formate dehydrogenase (NAD+) activity
CH58_RS13365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH58_RS13410	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH58_RS13420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH58_RS13425	COG1053	succinate dehydrogenase
CH58_RS13440	COG3264	Mechanosensitive ion channel
CH58_RS13440	COG1511	domain protein
CH58_RS13460	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH58_RS13480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH58_RS13485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH58_RS13485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH58_RS13490	COG0802	atpase or kinase
CH58_RS13495	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH58_RS13515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH58_RS13520	COG0330	HflC and HflK could
CH58_RS13525	COG0330	HflC and HflK could
CH58_RS13530	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH58_RS13545	COG0557	exoribonuclease II activity
CH58_RS13550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH58_RS13555	COG1960	acyl-CoA dehydrogenase activity
CH58_RS13560	COG3650	response to hydrogen peroxide
CH58_RS13580	COG1401	restriction endodeoxyribonuclease activity
CH58_RS13595	COG2963	transposase activity
CH58_RS13650	COG4269	membrane
CH58_RS13660	COG2207	Transcriptional regulator
CH58_RS13665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH58_RS13670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH58_RS13675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH58_RS13680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH58_RS13680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS13680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS13730	COG1070	Carbohydrate kinase
CH58_RS13735	COG0859	PFAM glycosyl transferase family 9
CH58_RS13755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH58_RS13805	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH58_RS13810	COG0456	acetyltransferase
CH58_RS13820	COG2823	Periplasmic or secreted lipoprotein
CH58_RS13830	COG4667	esterase of the alpha-beta hydrolase superfamily
CH58_RS13835	COG0084	hydrolase, TatD family'
CH58_RS13840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH58_RS13870	COG3726	membrane protein affecting hemolysin expression
CH58_RS13875	COG0560	Phosphoserine phosphatase
CH58_RS13895	COG0488	(ABC) transporter
CH58_RS13920	COG2271	Major facilitator Superfamily
CH58_RS13945	COG2831	hemolysin activation secretion protein
CH58_RS13955	COG0747	negative chemotaxis
CH58_RS13960	COG0601	transmembrane transport
CH58_RS13965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH58_RS13970	COG0444	Belongs to the ABC transporter superfamily
CH58_RS13975	COG4608	Belongs to the ABC transporter superfamily
CH58_RS13980	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH58_RS13985	COG2200	EAL domain
CH58_RS13985	COG2199	diguanylate cyclase activity
CH58_RS13990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH58_RS14010	COG0612	Peptidase, M16
CH58_RS14015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH58_RS14020	COG1942	4-Oxalocrotonate Tautomerase
CH58_RS14025	COG2200	EAL domain
CH58_RS14030	COG2982	Protein involved in outer membrane biogenesis
CH58_RS14035	COG2134	cdp-diacylglycerol pyrophosphatase
CH58_RS14040	COG1295	ribonuclease BN
CH58_RS14065	COG1929	Belongs to the glycerate kinase type-1 family
CH58_RS14070	COG2610	gluconate transmembrane transporter activity
CH58_RS14075	COG3835	regulator
CH58_RS14080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH58_RS14085	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH58_RS14090	COG0339	signal peptide processing
CH58_RS14110	COG0589	response to stress
CH58_RS14130	COG0306	phosphate transporter
CH58_RS14135	COG2081	HI0933 family
CH58_RS14165	COG0191	fructose-bisphosphate aldolase activity
CH58_RS14185	COG1741	Belongs to the pirin family
CH58_RS14190	COG1609	Transcriptional regulator
CH58_RS14195	COG2610	gluconate transmembrane transporter activity
CH58_RS14200	COG3265	gluconokinase activity
CH58_RS14220	COG2095	MarC family integral membrane protein
CH58_RS14225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH58_RS14255	COG3275	phosphorelay sensor kinase activity
CH58_RS14280	COG0058	SHG alpha-glucan phosphorylase activity
CH58_RS14285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH58_RS14310	COG2801	Transposase and inactivated derivatives
CH58_RS14335	COG0435	Glutathione S-transferase
CH58_RS14340	COG0583	DNA-binding transcription factor activity
CH58_RS14345	COG1741	Belongs to the pirin family
CH58_RS14350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH58_RS14370	COG2823	Periplasmic or secreted lipoprotein
CH58_RS14380	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH58_RS14390	COG2198	Histidine kinase
CH58_RS14390	COG5002	protein histidine kinase activity
CH58_RS14390	COG0784	Response regulator, receiver
CH58_RS14400	COG1242	4 iron, 4 sulfur cluster binding
CH58_RS14405	COG0069	glutamate synthase activity
CH58_RS14405	COG0070	glutamate synthase
CH58_RS14405	COG0067	glutamate synthase
CH58_RS14410	COG0493	'glutamate synthase
CH58_RS14420	COG2969	positive regulation of protein catabolic process
CH58_RS14425	COG0625	glutathione transferase activity
CH58_RS14445	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH58_RS14450	COG3105	Protein conserved in bacteria
CH58_RS14455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH58_RS14465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH58_RS14475	COG5007	Belongs to the BolA IbaG family
CH58_RS14480	COG3113	response to antibiotic
CH58_RS14485	COG2854	intermembrane phospholipid transfer
CH58_RS14490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH58_RS14495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH58_RS14500	COG1127	ABC transporter
CH58_RS14505	COG0530	calcium, potassium:sodium antiporter activity
CH58_RS14510	COG0517	IMP dehydrogenase activity
CH58_RS14510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH58_RS14515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH58_RS14520	COG3117	lipopolysaccharide transmembrane transporter activity
CH58_RS14525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH58_RS14530	COG1137	ATPase activity
CH58_RS14535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH58_RS14555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS14580	COG1609	Transcriptional regulator
CH58_RS14585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH58_RS14585	COG1263	PTS System
CH58_RS14590	COG0366	Alpha amylase catalytic
CH58_RS14595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH58_RS14600	COG3783	Cytochrome b(562)
CH58_RS14610	COG0312	modulator of DNA gyrase
CH58_RS14620	COG2732	(Barnase) inhibitor
CH58_RS14635	COG1012	belongs to the aldehyde dehydrogenase family
CH58_RS14655	COG0583	DNA-binding transcription factor activity
CH58_RS14715	COG0312	modulator of DNA gyrase
CH58_RS14720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH58_RS14725	COG3164	Protein of unknown function
CH58_RS14730	COG1530	ribonuclease E activity
CH58_RS14735	COG0424	maF-like protein
CH58_RS14740	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH58_RS14745	COG1792	Involved in formation and maintenance of cell shape
CH58_RS14750	COG1077	Cell shape determining protein MreB Mrl
CH58_RS14755	COG2199	diguanylate cyclase activity
CH58_RS14755	COG2200	EAL domain
CH58_RS14760	COG0604	alcohol dehydrogenase
CH58_RS14765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH58_RS14780	COG0511	ligase activity, forming carbon-carbon bonds
CH58_RS14785	COG0439	Biotin carboxylase
CH58_RS14790	COG3924	membrane
CH58_RS14795	COG4145	pantothenate transmembrane transporter activity
CH58_RS14805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH58_RS14810	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH58_RS14835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH58_RS14845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH58_RS14850	COG3133	Outer membrane lipoprotein
CH58_RS14860	COG1278	Cold shock
CH58_RS14865	COG1278	Cold shock
CH58_RS14890	COG0625	glutathione transferase activity
CH58_RS14900	COG1069	ribulokinase activity
CH58_RS14910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS14915	COG1129	ABC transporter
CH58_RS14925	COG1560	Kdo2-lipid A biosynthetic process
CH58_RS14935	COG0025	NhaP-type Na H and K H
CH58_RS14940	COG2252	PERMEase
CH58_RS14945	COG3077	Addiction module antitoxin, RelB DinJ family
CH58_RS14955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH58_RS14965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH58_RS14970	COG0431	NADPH-dependent FMN reductase
CH58_RS14975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH58_RS14980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH58_RS14985	COG1869	D-ribose catabolic process
CH58_RS14990	COG2207	Transcriptional regulator
CH58_RS14990	COG1917	Cupin 2, conserved barrel domain protein
CH58_RS14995	COG0673	inositol 2-dehydrogenase activity
CH58_RS15040	COG0250	Participates in transcription elongation, termination and antitermination
CH58_RS15105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH58_RS15145	COG1515	deoxyribonuclease V activity
CH58_RS15165	COG0151	Belongs to the GarS family
CH58_RS15210	COG2801	Transposase and inactivated derivatives
CH58_RS15300	COG3047	cAMP biosynthetic process
CH58_RS15300	COG2885	chlorophyll binding
CH58_RS15320	COG0417	DNA replication proofreading
CH58_RS15325	COG0586	Pfam SNARE associated Golgi protein
CH58_RS15330	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CH58_RS15335	COG1178	ABC-type Fe3 transport system permease component
CH58_RS15340	COG4143	(ABC) transporter
CH58_RS15360	COG2814	Major facilitator Superfamily
CH58_RS15375	COG2814	Major facilitator Superfamily
CH58_RS15390	COG0473	3-isopropylmalate dehydrogenase activity
CH58_RS15420	COG1022	Amp-dependent synthetase and ligase
CH58_RS15430	COG0028	Belongs to the TPP enzyme family
CH58_RS15450	COG1609	Transcriptional regulator
CH58_RS15470	COG3116	cell division
CH58_RS15475	COG0768	penicillin binding
CH58_RS15480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH58_RS15485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH58_RS15500	COG0772	Belongs to the SEDS family
CH58_RS15520	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH58_RS15525	COG0849	cell division
CH58_RS15530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH58_RS15555	COG0494	nUDIX hydrolase
CH58_RS15615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH58_RS15620	COG2224	Isocitrate lyase
CH58_RS15630	COG1414	Transcriptional regulator
CH58_RS15635	COG1414	Transcriptional regulator
CH58_RS15655	COG0527	aspartate kinase activity
CH58_RS15670	COG3833	ABC-type maltose transport systems, permease component
CH58_RS15675	COG1175	transmembrane transport
CH58_RS15735	COG2801	Transposase and inactivated derivatives
CH58_RS15765	COG0195	Participates in both transcription termination and antitermination
CH58_RS15785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH58_RS15795	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH58_RS15810	COG1534	Rna-binding protein
CH58_RS15820	COG2027	D-alanyl-D-alanine carboxypeptidase
CH58_RS15825	COG0745	RESPONSE REGULATOR receiver
CH58_RS15830	COG0642	Histidine kinase
CH58_RS15840	COG0697	spore germination
CH58_RS15855	COG0142	geranyltranstransferase activity
CH58_RS15865	COG3423	Transcriptional regulator
CH58_RS15890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH58_RS15895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH58_RS15900	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH58_RS15905	COG2105	PFAM AIG2 family protein
CH58_RS15910	COG2911	Protein conserved in bacteria
CH58_RS15915	COG0729	surface antigen
CH58_RS15925	COG1253	flavin adenine dinucleotide binding
CH58_RS15935	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH58_RS15945	COG0737	Belongs to the 5'-nucleotidase family
CH58_RS15955	COG0545	Peptidyl-prolyl cis-trans isomerase
CH58_RS15960	COG3061	Opacity-associated protein A
CH58_RS15985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH58_RS15995	COG0360	Binds together with S18 to 16S ribosomal RNA
CH58_RS16005	COG1073	alpha beta
CH58_RS16030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH58_RS16050	COG1629	transport
CH58_RS16075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH58_RS16080	COG0678	peroxiredoxin activity
CH58_RS16080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH58_RS16160	COG1879	ABC-type sugar transport system periplasmic component
CH58_RS16165	COG1129	ABC transporter
CH58_RS16170	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS16175	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS16185	COG3085	chromosome segregation
CH58_RS16200	COG3978	acetolactate synthase activity
CH58_RS16205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH58_RS16245	COG0583	DNA-binding transcription factor activity
CH58_RS16285	COG3121	Chaperone
CH58_RS16300	COG3121	Chaperone
CH58_RS16315	COG3328	transposase activity
CH58_RS16325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH58_RS16355	COG3118	belongs to the thioredoxin family
CH58_RS16360	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH58_RS16365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH58_RS16370	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH58_RS16375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH58_RS16380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH58_RS16385	COG1088	dTDP-glucose 4,6-dehydratase activity
CH58_RS16390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH58_RS16395	COG0456	acetyltransferase
CH58_RS16400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH58_RS16405	COG2244	polysaccharide biosynthetic process
CH58_RS16425	COG1113	amino acid transport
CH58_RS16465	COG3071	HemY protein
CH58_RS16470	COG2959	enzyme of heme biosynthesis
CH58_RS16475	COG1587	Uroporphyrinogen-III synthase
CH58_RS16490	COG3072	Adenylate cyclase
CH58_RS16510	COG3159	Protein conserved in bacteria
CH58_RS16515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH58_RS16520	COG1011	Hydrolase
CH58_RS16525	COG0210	DNA helicase
CH58_RS16535	COG5441	Belongs to the UPF0261 family
CH58_RS16540	COG5564	TIM-barrel signal transduction protein
CH58_RS16555	COG2050	protein possibly involved in aromatic compounds catabolism
CH58_RS16560	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH58_RS16565	COG0514	ATP-dependent DNA helicase (RecQ)
CH58_RS16570	COG1280	lysine exporter protein (LysE YggA)
CH58_RS16575	COG1280	lysine exporter protein (LysE YggA)
CH58_RS16580	COG2267	carboxylic ester hydrolase activity
CH58_RS16585	COG0561	phosphatase activity
CH58_RS16595	COG0584	glycerophosphoryl diester phosphodiesterase
CH58_RS16605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH58_RS16615	COG0247	lactate metabolic process
CH58_RS16625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH58_RS16655	COG3776	membrane
CH58_RS16660	COG0742	ribosomal rna small subunit methyltransferase
CH58_RS16670	COG0552	protein localization to endoplasmic reticulum
CH58_RS16670	COG0552	protein localization to endoplasmic reticulum
CH58_RS16675	COG2884	Cell division ATP-binding protein ftsE
CH58_RS16680	COG2177	Part of the ABC transporter FtsEX involved in
CH58_RS16705	COG0683	leucine binding
CH58_RS16725	COG4177	L-phenylalanine transmembrane transporter activity
CH58_RS16735	COG0410	ABC transporter
CH58_RS16795	COG0584	glycerophosphoryl diester phosphodiesterase
CH58_RS16800	COG0679	Auxin Efflux Carrier
CH58_RS16805	COG0697	spore germination
CH58_RS16810	COG0583	DNA-binding transcription factor activity
CH58_RS16820	COG0412	Dienelactone hydrolase
CH58_RS16835	COG1966	Carbon starvation protein
CH58_RS16840	COG0586	Pfam SNARE associated Golgi protein
CH58_RS16845	COG1322	Protein conserved in bacteria
CH58_RS16865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH58_RS16875	COG0805	protein transport
CH58_RS16905	COG1575	Belongs to the MenA family. Type 1 subfamily
CH58_RS16920	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH58_RS16925	COG1609	Transcriptional regulator
CH58_RS16935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH58_RS16945	COG4682	membrane
CH58_RS16965	COG0527	aspartate kinase activity
CH58_RS16965	COG0460	homoserine dehydrogenase
CH58_RS16975	COG2801	Transposase and inactivated derivatives
CH58_RS16985	COG2211	Major facilitator Superfamily
CH58_RS17035	COG2771	luxR family
CH58_RS17040	COG3916	Acyl-homoserine-lactone synthase
CH58_RS17175	COG1982	Orn Lys Arg decarboxylase major
CH58_RS17180	COG1879	ABC-type sugar transport system periplasmic component
CH58_RS17185	COG1129	ABC transporter
CH58_RS17190	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS17195	COG4774	siderophore transport
CH58_RS17215	COG1194	a g-specific adenine glycosylase
CH58_RS17225	COG3171	Protein conserved in bacteria
CH58_RS17250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH58_RS17255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH58_RS17265	COG0762	integral membrane protein
CH58_RS17270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH58_RS17275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH58_RS17280	COG2805	Type II/IV secretion system protein
CH58_RS17290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH58_RS17305	COG0189	ligase activity
CH58_RS17310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH58_RS17315	COG2356	endonuclease I
CH58_RS17330	COG1166	arginine decarboxylase activity
CH58_RS17345	COG0501	Belongs to the peptidase M48B family
CH58_RS17350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH58_RS17375	COG0191	fructose-bisphosphate aldolase activity
CH58_RS17425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH58_RS17430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH58_RS17445	COG0006	proline dipeptidase activity
CH58_RS17450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH58_RS17455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH58_RS17485	COG5295	Hep Hag repeat protein
CH58_RS17495	COG1272	protein, Hemolysin III
CH58_RS17520	COG0745	RESPONSE REGULATOR receiver
CH58_RS17525	COG2205	protein histidine kinase activity
CH58_RS17530	COG4452	Inner membrane protein CreD
CH58_RS17535	COG0716	FMN binding
CH58_RS17540	COG4974	Belongs to the 'phage' integrase family
CH58_RS17545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH58_RS17550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH58_RS17570	COG0582	viral genome integration into host DNA
CH58_RS17585	COG0582	viral genome integration into host DNA
CH58_RS17615	COG2944	sequence-specific DNA binding
CH58_RS17710	COG1695	Transcriptional regulator
CH58_RS17715	COG0791	NLP P60 protein
CH58_RS17725	COG1879	ABC-type sugar transport system periplasmic component
CH58_RS17730	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS17735	COG1129	ABC transporter
CH58_RS17745	COG2182	Extracellular solute-binding protein
CH58_RS17750	COG1175	transmembrane transport
CH58_RS17755	COG3833	ABC-type maltose transport systems, permease component
CH58_RS17760	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH58_RS17765	COG1874	Beta-galactosidase
CH58_RS17770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH58_RS17770	COG1263	PTS System
CH58_RS17790	COG2271	Major facilitator Superfamily
CH58_RS17820	COG3119	arylsulfatase activity
CH58_RS17825	COG0641	radical SAM
CH58_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS17845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS17850	COG3716	PTS system mannose fructose sorbose family IID component
CH58_RS17855	COG3715	PTS system
CH58_RS17860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH58_RS17865	COG2222	sugar isomerase
CH58_RS17875	COG1349	DNA-binding transcription factor activity
CH58_RS17880	COG3119	arylsulfatase activity
CH58_RS17930	COG0288	reversible hydration of carbon dioxide
CH58_RS17950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH58_RS18015	COG0840	transmembrane signaling receptor activity
CH58_RS18030	COG0583	DNA-binding transcription factor activity
CH58_RS18035	COG2814	Major facilitator Superfamily
CH58_RS18040	COG0583	DNA-binding transcription factor activity
CH58_RS18050	COG1609	Transcriptional regulator
CH58_RS18080	COG0667	Aldo Keto reductase
CH58_RS18145	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH58_RS18155	COG1074	ATP-dependent DNA helicase activity
CH58_RS18160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH58_RS18170	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH58_RS18185	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH58_RS18190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH58_RS18195	COG2166	iron-sulfur cluster assembly
CH58_RS18200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH58_RS18205	COG0583	DNA-binding transcription factor activity
CH58_RS18210	COG2363	Small membrane protein
CH58_RS18240	COG1611	Belongs to the LOG family
CH58_RS18260	COG3098	single-species biofilm formation
CH58_RS18265	COG0564	pseudouridine synthase activity
CH58_RS18335	COG0575	Belongs to the CDS family
CH58_RS18340	COG0750	zinc metalloprotease
CH58_RS18355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH58_RS18380	COG0587	DNA-directed DNA polymerase activity
CH58_RS18390	COG0346	lactoylglutathione lyase activity
CH58_RS18395	COG0037	tRNA processing
CH58_RS18405	COG4568	rho-dependent transcription termination
CH58_RS18415	COG4681	YaeQ
CH58_RS18425	COG3015	lipoprotein NlpE involved in copper resistance
CH58_RS18435	COG1720	tRNA m6t6A37 methyltransferase activity
CH58_RS18445	COG1464	Belongs to the NlpA lipoprotein family
CH58_RS18450	COG2011	ABC-type metal ion transport system permease component
CH58_RS18460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH58_RS18495	COG0656	L-ascorbic acid biosynthetic process
CH58_RS18510	COG0741	lytic transglycosylase activity
CH58_RS18510	COG1388	LysM domain
CH58_RS18515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH58_RS18520	COG2226	methyltransferase
CH58_RS18540	COG1953	Uracil, thiamine, allantoin
CH58_RS18575	COG3657	addiction module killer protein
CH58_RS18635	COG0582	viral genome integration into host DNA
CH58_RS18655	COG2867	negative regulation of translational initiation
CH58_RS18665	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH58_RS18670	COG0497	DNA recombination
CH58_RS18675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH58_RS18690	COG2009	succinate dehydrogenase
CH58_RS18695	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH58_RS18700	COG1053	succinate dehydrogenase
CH58_RS18710	COG0567	Dehydrogenase, E1 component
CH58_RS18715	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH58_RS18725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH58_RS18730	COG1271	oxidase subunit
CH58_RS18735	COG1294	oxidase, subunit
CH58_RS18740	COG4890	Cyd operon protein YbgT
CH58_RS18745	COG3790	cyd operon protein YbgE
CH58_RS18750	COG0824	Thioesterase
CH58_RS18755	COG0811	peptide transport
CH58_RS18760	COG0848	biopolymer transport protein
CH58_RS18765	COG3064	Membrane
CH58_RS18765	COG3064	Membrane
CH58_RS18775	COG2885	chlorophyll binding
CH58_RS18780	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH58_RS18805	COG1230	cation diffusion facilitator family transporter
CH58_RS18810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH58_RS18825	COG1686	Belongs to the peptidase S11 family
CH58_RS18835	COG0814	amino acid
CH58_RS18840	COG1349	DNA-binding transcription factor activity
CH58_RS18850	COG0671	phosphoesterase, PA-phosphatase related
CH58_RS18885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH58_RS18890	COG3842	ATPase activity
CH58_RS18895	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH58_RS18900	COG1177	transmembrane transport
CH58_RS18915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS18945	COG1120	ATPase activity
CH58_RS18970	COG4160	amino acid transport
CH58_RS18975	COG4215	(ABC) transporter
CH58_RS18980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS18985	COG1126	abc transporter atp-binding protein
CH58_RS18990	COG1605	Chorismate mutase
CH58_RS19000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH58_RS19005	COG0702	epimerase
CH58_RS19010	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH58_RS19015	COG0028	Belongs to the TPP enzyme family
CH58_RS19020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH58_RS19030	COG2431	L-lysine efflux transmembrane transporter activity
CH58_RS19035	COG3593	DNA synthesis involved in DNA repair
CH58_RS19045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH58_RS19055	COG1278	Cold shock
CH58_RS19065	COG0542	response to heat
CH58_RS19075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH58_RS19085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH58_RS19100	COG0492	ferredoxin-NADP+ reductase activity
CH58_RS19110	COG3107	peptidoglycan biosynthetic process
CH58_RS19110	COG1674	ftsk spoiiie
CH58_RS19120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH58_RS19135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH58_RS19145	COG1882	Formate acetyltransferase
CH58_RS19150	COG2116	formate transmembrane transporter activity
CH58_RS19155	COG1944	ATP diphosphatase activity
CH58_RS19160	COG0252	asparaginase activity
CH58_RS19165	COG5295	Hep Hag repeat protein
CH58_RS19165	COG5295	Hep Hag repeat protein
CH58_RS19190	COG0539	negative regulation of cytoplasmic translation
CH58_RS19205	COG0658	competence protein
CH58_RS19205	COG2333	competence protein COMEC
CH58_RS19235	COG5383	Protein conserved in bacteria
CH58_RS19245	COG1278	Cold shock
CH58_RS19260	COG3173	Aminoglycoside phosphotransferase
CH58_RS19270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH58_RS19300	COG2989	Protein conserved in bacteria
CH58_RS19305	COG3108	Peptidase M15
CH58_RS19310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH58_RS19315	COG1448	Aminotransferase
CH58_RS19335	COG0308	aminopeptidase N
CH58_RS19350	COG0633	Ferredoxin
CH58_RS19350	COG3217	Mosc domain protein beta barrel domain protein
CH58_RS19360	COG0488	(ABC) transporter
CH58_RS19365	COG2995	paraquat-inducible protein a
CH58_RS19370	COG3008	intermembrane lipid transfer
CH58_RS19370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH58_RS19375	COG3009	Protein conserved in bacteria
CH58_RS19385	COG3130	regulation of translation
CH58_RS19400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH58_RS19420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH58_RS19435	COG1067	ATP-dependent peptidase activity
CH58_RS19465	COG3070	regulator of competence-specific genes
CH58_RS19470	COG1289	transmembrane transporter activity
CH58_RS19475	COG3304	Inner membrane component domain
CH58_RS19480	COG0210	DNA helicase
CH58_RS19495	COG1832	CoA-binding protein
CH58_RS19515	COG2920	part of a sulfur-relay system
CH58_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS19560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH58_RS19565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH58_RS19570	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS19575	COG3425	synthase
CH58_RS19585	COG1024	Enoyl-CoA hydratase
CH58_RS19590	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS19600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH58_RS19605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH58_RS19760	COG0488	(ABC) transporter
CH58_RS19770	COG3328	transposase activity
CH58_RS19780	COG0303	'Molybdopterin
CH58_RS19790	COG1136	(ABC) transporter
CH58_RS19825	COG0583	DNA-binding transcription factor activity
CH58_RS19830	COG0477	Major facilitator Superfamily
CH58_RS19840	COG2311	Membrane
CH58_RS19855	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH58_RS19860	COG2949	membrane
CH58_RS19875	COG1346	cytolysis
CH58_RS19885	COG2814	Major facilitator Superfamily
CH58_RS19920	COG0489	protein tyrosine kinase activity
CH58_RS19935	COG2982	Protein involved in outer membrane biogenesis
CH58_RS19940	COG1253	flavin adenine dinucleotide binding
CH58_RS19945	COG4114	ferric iron reductase
CH58_RS19950	COG0076	glutamate decarboxylase activity
CH58_RS19955	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH58_RS19970	COG1120	ATPase activity
CH58_RS19975	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH58_RS19980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH58_RS19985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH58_RS20000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH58_RS20005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH58_RS20015	COG0140	phosphoribosyl-ATP diphosphatase activity
CH58_RS20015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH58_RS20035	COG0131	Imidazoleglycerol-phosphate dehydratase
CH58_RS20035	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH58_RS20045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH58_RS20055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH58_RS20065	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS20070	COG1129	ABC transporter
CH58_RS20075	COG1129	ABC transporter
CH58_RS20080	COG0371	Dehydrogenase
CH58_RS20090	COG0531	amino acid
CH58_RS20095	COG2925	Exonuclease
CH58_RS20110	COG3328	transposase activity
CH58_RS20115	COG1470	cell adhesion involved in biofilm formation
CH58_RS20115	COG1388	LysM domain
CH58_RS20120	COG2271	Major facilitator Superfamily
CH58_RS20125	COG3011	Protein conserved in bacteria
CH58_RS20130	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS20140	COG4948	Mandelate Racemase Muconate Lactonizing
CH58_RS20155	COG0534	Mate efflux family protein
CH58_RS20175	COG3122	Protein conserved in bacteria
CH58_RS20200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH58_RS20220	COG2223	nitrite transmembrane transporter activity
CH58_RS20235	COG0513	Belongs to the DEAD box helicase family
CH58_RS20255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH58_RS20265	COG1686	Belongs to the peptidase S11 family
CH58_RS20270	COG0277	FAD linked oxidase domain protein
CH58_RS20290	COG2261	transglycosylase associated protein
CH58_RS20300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH58_RS20315	COG4807	Protein conserved in bacteria
CH58_RS20335	COG1122	ATPase activity
CH58_RS20355	COG2897	thiosulfate sulfurtransferase activity
CH58_RS20360	COG1732	Glycine betaine
CH58_RS20365	COG1732	Glycine betaine
CH58_RS20370	COG1174	glycine betaine transport
CH58_RS20375	COG1125	glycine betaine transport
CH58_RS20380	COG1174	glycine betaine transport
CH58_RS20385	COG0531	amino acid
CH58_RS20390	COG1982	Orn Lys Arg decarboxylase major
CH58_RS20400	COG0697	spore germination
CH58_RS20440	COG0814	amino acid
CH58_RS20455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH58_RS20485	COG0784	Response regulator, receiver
CH58_RS20485	COG2205	protein histidine kinase activity
CH58_RS20495	COG2198	Histidine kinase
CH58_RS20495	COG0642	Histidine kinase
CH58_RS20500	COG2198	Histidine kinase
CH58_RS20500	COG0642	Histidine kinase
CH58_RS20505	COG2223	nitrite transmembrane transporter activity
CH58_RS20535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH58_RS20580	COG3395	kinase activity
CH58_RS20590	COG1349	DNA-binding transcription factor activity
CH58_RS20595	COG3622	Belongs to the hyi family
CH58_RS20615	COG4386	tail sheath protein
CH58_RS20655	COG3299	homolog of phage Mu protein gp47
CH58_RS20675	COG1737	Transcriptional regulator
CH58_RS20680	COG2723	6-phospho-beta-galactosidase activity
CH58_RS20700	COG3157	Type VI secretion system effector, Hcp
CH58_RS20720	COG3157	Type VI secretion system effector, Hcp
CH58_RS20735	COG3083	sulfuric ester hydrolase activity
CH58_RS20740	COG3082	Protein of unknown function (DUF1414)
CH58_RS20765	COG1061	Type III restriction enzyme res subunit
CH58_RS20770	COG1187	pseudouridine synthase activity
CH58_RS20775	COG2814	Major facilitator Superfamily
CH58_RS20785	COG4172	Belongs to the ABC transporter superfamily
CH58_RS20790	COG4239	(ABC) transporter, permease
CH58_RS20795	COG4174	ABC transporter (Permease)
CH58_RS20800	COG4166	transmembrane transport
CH58_RS20805	COG2200	EAL domain
CH58_RS20810	COG0791	NLP P60 protein
CH58_RS20815	COG0671	phosphoesterase, PA-phosphatase related
CH58_RS20820	COG0523	cobalamin synthesis protein
CH58_RS20830	COG2186	Transcriptional regulator
CH58_RS20835	COG0246	Mannitol dehydrogenase
CH58_RS20860	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS20875	COG2801	Transposase and inactivated derivatives
CH58_RS20905	COG1129	ABC transporter
CH58_RS20915	COG0494	nUDIX hydrolase
CH58_RS20925	COG1105	Belongs to the carbohydrate kinase PfkB family
CH58_RS20930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH58_RS20930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH58_RS20930	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH58_RS20935	COG3710	Transcriptional regulator
CH58_RS20950	COG3121	Chaperone
CH58_RS20955	COG3188	usher protein
CH58_RS20965	COG2855	membrane
CH58_RS20970	COG0583	DNA-binding transcription factor activity
CH58_RS20975	COG0833	amino acid
CH58_RS20985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH58_RS20995	COG4771	TonB-dependent receptor
CH58_RS21000	COG0625	glutathione transferase activity
CH58_RS21025	COG2011	ABC-type metal ion transport system permease component
CH58_RS21030	COG1686	Belongs to the peptidase S11 family
CH58_RS21045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH58_RS21060	COG2017	converts alpha-aldose to the beta-anomer
CH58_RS21075	COG1085	galactose-1-phosphate uridylyltransferase
CH58_RS21080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH58_RS21095	COG1119	ATPase activity
CH58_RS21100	COG3585	molybdate ion transport
CH58_RS21100	COG2005	Transcriptional regulator
CH58_RS21110	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH58_RS21115	COG4149	molybdate abc transporter
CH58_RS21125	COG0561	phosphatase activity
CH58_RS21150	COG2226	methyltransferase
CH58_RS21160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CH58_RS21170	COG4628	conserved protein (DUF2132)
CH58_RS21175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH58_RS21185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH58_RS21195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH58_RS21200	COG0314	molybdopterin synthase activity
CH58_RS21205	COG0670	Belongs to the BI1 family
CH58_RS21235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH58_RS21240	COG0583	DNA-binding transcription factor activity
CH58_RS21250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH58_RS21255	COG2211	Major facilitator Superfamily
CH58_RS21265	COG2211	Major facilitator Superfamily
CH58_RS21285	COG1902	pentaerythritol trinitrate reductase activity
CH58_RS21305	COG0842	Transport permease protein
CH58_RS21310	COG0842	Transport permease protein
CH58_RS21315	COG1131	(ABC) transporter
CH58_RS21325	COG1309	transcriptional regulator
CH58_RS21330	COG0513	Belongs to the DEAD box helicase family
CH58_RS21360	COG3328	transposase activity
CH58_RS21415	COG1132	(ABC) transporter
CH58_RS21425	COG2207	Transcriptional regulator
CH58_RS21460	COG1113	amino acid transport
CH58_RS21485	COG1496	oxidoreductase activity
CH58_RS21490	COG2226	methyltransferase
CH58_RS21500	COG3447	MASE1 domain protein
CH58_RS21500	COG5001	Diguanylate cyclase
CH58_RS21500	COG5002	protein histidine kinase activity
CH58_RS21520	COG3716	PTS system mannose fructose sorbose family IID component
CH58_RS21525	COG3715	PTS system
CH58_RS21530	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH58_RS21530	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH58_RS21535	COG1253	flavin adenine dinucleotide binding
CH58_RS21540	COG1846	Transcriptional regulator
CH58_RS21555	COG1012	belongs to the aldehyde dehydrogenase family
CH58_RS21560	COG3384	dioxygenase
CH58_RS21570	COG3971	2-oxopent-4-enoate hydratase activity
CH58_RS21585	COG2368	4-hydroxyphenylacetate
CH58_RS21595	COG1760	l-serine dehydratase
CH58_RS21620	COG0513	Belongs to the DEAD box helicase family
CH58_RS21625	COG3141	response to X-ray
CH58_RS21640	COG1770	oligopeptidase
CH58_RS21670	COG1528	Iron-storage protein
CH58_RS21675	COG2372	response to copper ion
CH58_RS21705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH58_RS21710	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH58_RS21735	COG3418	PFAM FlgN family protein
CH58_RS21740	COG2747	anti-sigma28 factor FlgM
CH58_RS21750	COG1815	bacterial-type flagellum-dependent cell motility
CH58_RS21755	COG1558	bacterial-type flagellum-dependent cell motility
CH58_RS21795	COG1256	bacterial-type flagellum assembly
CH58_RS21805	COG2390	Transcriptional regulator
CH58_RS21810	COG3347	Dehydrogenase
CH58_RS21810	COG1028	Short-chain dehydrogenase reductase Sdr
CH58_RS21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH58_RS21825	COG1129	ABC transporter
CH58_RS21835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH58_RS21855	COG1987	bacterial-type flagellum assembly
CH58_RS21880	COG1580	Controls the rotational direction of flagella during chemotaxis
CH58_RS21895	COG1157	protein secretion by the type III secretion system
CH58_RS21915	COG1677	Flagellar hook-basal body complex protein FliE
CH58_RS21930	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH58_RS21935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH58_RS21940	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH58_RS21975	COG1191	sigma factor activity
CH58_RS21990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS21995	COG0765	amino acid transport
CH58_RS22000	COG1126	abc transporter atp-binding protein
CH58_RS22030	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH58_RS22030	COG0506	proline dehydrogenase activity
CH58_RS22030	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH58_RS22045	COG0672	)-iron permease
CH58_RS22050	COG2822	iron ion transport
CH58_RS22070	COG1113	amino acid transport
CH58_RS22090	COG3136	membrane protein required for alginate biosynthesis
CH58_RS22100	COG2197	response regulator
CH58_RS22240	COG2188	Transcriptional regulator
CH58_RS22250	COG0673	inositol 2-dehydrogenase activity
CH58_RS22260	COG1175	transmembrane transport
CH58_RS22265	COG0395	ABC-type sugar transport system, permease component
CH58_RS22270	COG3842	ATPase activity
CH58_RS22340	COG4771	TonB-dependent receptor
CH58_RS22345	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH58_RS22365	COG3433	isochorismatase activity
CH58_RS22365	COG2226	methyltransferase
CH58_RS22365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH58_RS22380	COG1132	(ABC) transporter
CH58_RS22385	COG2814	Major facilitator Superfamily
CH58_RS22390	COG1169	isochorismate synthase
CH58_RS22395	COG0582	viral genome integration into host DNA
CH58_RS22405	COG3121	Chaperone
CH58_RS22415	COG3188	usher protein
CH58_RS22430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH58_RS22430	COG2205	protein histidine kinase activity
CH58_RS22440	COG0427	acetyl-CoA hydrolase
CH58_RS22445	COG2030	dehydratase
CH58_RS22470	COG2814	Major facilitator Superfamily
CH58_RS22500	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH58_RS22505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH58_RS22515	COG1349	DNA-binding transcription factor activity
CH58_RS22525	COG2066	Belongs to the glutaminase family
CH58_RS22535	COG0672	)-iron permease
CH58_RS22550	COG1136	(ABC) transporter
CH58_RS22550	COG0577	efflux transmembrane transporter activity
CH58_RS22560	COG1136	(ABC) transporter
CH58_RS22560	COG0577	efflux transmembrane transporter activity
CH58_RS22580	COG0006	proline dipeptidase activity
CH58_RS22585	COG0457	Tetratricopeptide repeat
CH58_RS22590	COG1649	PFAM Uncharacterised BCR, COG1649
CH58_RS22590	COG0726	polysaccharide deacetylase
CH58_RS22595	COG1215	transferase activity, transferring glycosyl groups
CH58_RS22600	COG3658	cytochrome
CH58_RS22615	COG1702	phosphate starvation-inducible protein PhoH
CH58_RS22620	COG0387	Pfam Sodium calcium exchanger
CH58_RS22625	COG3850	Histidine kinase
CH58_RS22630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH58_RS22695	COG0402	S-adenosylhomocysteine deaminase activity
CH58_RS22710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH58_RS22715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH58_RS22720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH58_RS22765	COG3328	transposase activity
CH58_RS22790	COG0500	methyltransferase
CH58_RS22830	COG5002	protein histidine kinase activity
CH58_RS22885	COG0012	GTP binding
CH58_RS22905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH58_RS22935	COG2890	protein-(glutamine-N5) methyltransferase activity
CH58_RS22955	COG0659	secondary active sulfate transmembrane transporter activity
CH58_RS22970	COG0659	secondary active sulfate transmembrane transporter activity
CH58_RS22995	COG3833	ABC-type maltose transport systems, permease component
CH58_RS23000	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH58_RS23015	COG3842	ATPase activity
CH58_RS23020	COG0584	glycerophosphoryl diester phosphodiesterase
CH58_RS23025	COG1940	carbohydrate kinase activity
CH58_RS23040	COG3381	protein complex oligomerization
CH58_RS23055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH58_RS23060	COG0673	inositol 2-dehydrogenase activity
CH58_RS23065	COG0728	peptidoglycan biosynthetic process
CH58_RS23085	COG3102	Protein conserved in bacteria