locus-tag	class	description
ISU54_RS00010	COG0592	DNA-directed DNA polymerase activity
ISU54_RS00025	COG0187	DNA topoisomerase II activity
ISU54_RS00030	COG0561	phosphatase activity
ISU54_RS00040	COG2423	ornithine cyclodeaminase activity
ISU54_RS00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISU54_RS00055	COG5645	(Lipo)protein
ISU54_RS00075	COG3977	Valine--pyruvate aminotransferase
ISU54_RS00085	COG0366	Alpha amylase catalytic
ISU54_RS00100	COG2885	chlorophyll binding
ISU54_RS00110	COG2818	Glycosylase
ISU54_RS00135	COG2213	PTS system mannitol-specific
ISU54_RS00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS00145	COG3722	fumarate hydratase activity
ISU54_RS00170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISU54_RS00185	COG0437	4 iron, 4 sulfur cluster binding
ISU54_RS00190	COG2864	formate dehydrogenase
ISU54_RS00205	COG3276	selenocysteine insertion sequence binding
ISU54_RS00250	COG3274	enterobacterial common antigen metabolic process
ISU54_RS00275	COG1070	Carbohydrate kinase
ISU54_RS00285	COG4213	ABC transporter substrate-binding protein
ISU54_RS00295	COG4214	carbohydrate transport
ISU54_RS00300	COG1609	Transcriptional regulator
ISU54_RS00300	COG2207	Transcriptional regulator
ISU54_RS00310	COG0582	viral genome integration into host DNA
ISU54_RS00355	COG4604	ABC transporter, ATP-binding protein
ISU54_RS00360	COG4605	iron ion homeostasis
ISU54_RS00370	COG4607	ABC-type enterochelin transport system periplasmic component
ISU54_RS00400	COG2986	histidine ammonia-lyase
ISU54_RS00415	COG2194	sulfuric ester hydrolase activity
ISU54_RS00420	COG2197	response regulator
ISU54_RS00440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISU54_RS00455	COG0551	DNA topoisomerase type I activity
ISU54_RS00465	COG0758	DNA mediated transformation
ISU54_RS00495	COG3036	rescue of stalled ribosome
ISU54_RS00500	COG0789	Transcriptional regulator
ISU54_RS00515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ISU54_RS00530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU54_RS00535	COG0201	protein transport
ISU54_RS00545	COG1841	ribosomal large subunit assembly
ISU54_RS00585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ISU54_RS00590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ISU54_RS00600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISU54_RS00605	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ISU54_RS00615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISU54_RS00625	COG0089	rRNA binding
ISU54_RS00640	COG0051	transcription antitermination factor activity, RNA binding
ISU54_RS00670	COG0049	tRNA binding
ISU54_RS00675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ISU54_RS00695	COG2964	Protein conserved in bacteria
ISU54_RS00700	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU54_RS00710	COG1047	Peptidyl-prolyl cis-trans
ISU54_RS00715	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISU54_RS00735	COG1216	Glycosyl transferase, family 2
ISU54_RS00745	COG2175	clavaminate synthase activity
ISU54_RS00750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU54_RS00760	COG4521	taurine ABC transporter
ISU54_RS00770	COG0429	hydrolase of the alpha beta-hydrolase fold
ISU54_RS00780	COG3954	Phosphoribulokinase
ISU54_RS00790	COG1765	OsmC-like protein
ISU54_RS00800	COG1289	transmembrane transporter activity
ISU54_RS00815	COG0433	COG0433 Predicted ATPase
ISU54_RS00820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU54_RS00825	COG1486	melibiose metabolic process
ISU54_RS00845	COG0402	S-adenosylhomocysteine deaminase activity
ISU54_RS00850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISU54_RS00870	COG0180	Tryptophanyl-tRNA synthetase
ISU54_RS00875	COG0546	phosphoglycolate phosphatase activity
ISU54_RS00880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISU54_RS00905	COG4796	Type ii and iii secretion system protein
ISU54_RS00930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISU54_RS00935	COG0494	nUDIX hydrolase
ISU54_RS00945	COG1011	Hydrolase
ISU54_RS00950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISU54_RS00975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU54_RS00980	COG2183	response to ionizing radiation
ISU54_RS00985	COG1918	ferrous iron import across plasma membrane
ISU54_RS01020	COG1640	4-alpha-glucanotransferase
ISU54_RS01025	COG0058	SHG alpha-glucan phosphorylase activity
ISU54_RS01030	COG0058	SHG alpha-glucan phosphorylase activity
ISU54_RS01050	COG1349	DNA-binding transcription factor activity
ISU54_RS01075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU54_RS01080	COG0058	SHG alpha-glucan phosphorylase activity
ISU54_RS01105	COG3275	phosphorelay sensor kinase activity
ISU54_RS01140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU54_RS01145	COG2095	MarC family integral membrane protein
ISU54_RS01160	COG3265	gluconokinase activity
ISU54_RS01165	COG2610	gluconate transmembrane transporter activity
ISU54_RS01170	COG1609	Transcriptional regulator
ISU54_RS01175	COG1741	Belongs to the pirin family
ISU54_RS01195	COG0191	fructose-bisphosphate aldolase activity
ISU54_RS01210	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS01225	COG2081	HI0933 family
ISU54_RS01230	COG0306	phosphate transporter
ISU54_RS01245	COG0589	response to stress
ISU54_RS01265	COG0339	signal peptide processing
ISU54_RS01270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISU54_RS01275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU54_RS01280	COG3835	regulator
ISU54_RS01290	COG2610	gluconate transmembrane transporter activity
ISU54_RS01295	COG1929	Belongs to the glycerate kinase type-1 family
ISU54_RS01320	COG1295	ribonuclease BN
ISU54_RS01325	COG2134	cdp-diacylglycerol pyrophosphatase
ISU54_RS01330	COG2982	Protein involved in outer membrane biogenesis
ISU54_RS01335	COG2200	EAL domain
ISU54_RS01340	COG1942	4-Oxalocrotonate Tautomerase
ISU54_RS01345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU54_RS01350	COG0612	Peptidase, M16
ISU54_RS01370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU54_RS01375	COG2200	EAL domain
ISU54_RS01375	COG2199	diguanylate cyclase activity
ISU54_RS01380	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISU54_RS01385	COG4608	Belongs to the ABC transporter superfamily
ISU54_RS01390	COG0444	Belongs to the ABC transporter superfamily
ISU54_RS01395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU54_RS01400	COG0601	transmembrane transport
ISU54_RS01405	COG0747	negative chemotaxis
ISU54_RS01410	COG2831	hemolysin activation secretion protein
ISU54_RS01425	COG2271	Major facilitator Superfamily
ISU54_RS01480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISU54_RS01485	COG2224	Isocitrate lyase
ISU54_RS01515	COG0527	aspartate kinase activity
ISU54_RS01530	COG3833	ABC-type maltose transport systems, permease component
ISU54_RS01535	COG1175	transmembrane transport
ISU54_RS01615	COG2885	chlorophyll binding
ISU54_RS01620	COG2199	diguanylate cyclase activity
ISU54_RS01635	COG0741	lytic transglycosylase activity
ISU54_RS01640	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ISU54_RS01655	COG2207	Transcriptional regulator
ISU54_RS01655	COG3708	Transcriptional regulator
ISU54_RS01660	COG3045	CreA protein
ISU54_RS01665	COG0745	RESPONSE REGULATOR receiver
ISU54_RS01705	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISU54_RS01720	COG1584	GPR1 FUN34 yaaH family protein
ISU54_RS01740	COG0583	DNA-binding transcription factor activity
ISU54_RS01750	COG0196	riboflavin kinase activity
ISU54_RS01765	COG1047	Peptidyl-prolyl cis-trans
ISU54_RS01790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISU54_RS01795	COG1280	lysine exporter protein (LysE YggA)
ISU54_RS01800	COG2966	Psort location CytoplasmicMembrane, score
ISU54_RS01810	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ISU54_RS01860	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISU54_RS01865	COG0564	pseudouridine synthase activity
ISU54_RS01950	COG2885	chlorophyll binding
ISU54_RS01950	COG3047	cAMP biosynthetic process
ISU54_RS01970	COG0417	DNA replication proofreading
ISU54_RS01975	COG0586	Pfam SNARE associated Golgi protein
ISU54_RS01980	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ISU54_RS01985	COG1178	ABC-type Fe3 transport system permease component
ISU54_RS01990	COG4143	(ABC) transporter
ISU54_RS02000	COG2814	Major facilitator Superfamily
ISU54_RS02015	COG0473	3-isopropylmalate dehydrogenase activity
ISU54_RS02040	COG1022	Amp-dependent synthetase and ligase
ISU54_RS02045	COG0028	Belongs to the TPP enzyme family
ISU54_RS02060	COG1609	Transcriptional regulator
ISU54_RS02085	COG3116	cell division
ISU54_RS02090	COG0768	penicillin binding
ISU54_RS02095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ISU54_RS02100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISU54_RS02115	COG0772	Belongs to the SEDS family
ISU54_RS02135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ISU54_RS02140	COG0849	cell division
ISU54_RS02145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISU54_RS02175	COG0494	nUDIX hydrolase
ISU54_RS02195	COG2259	Doxx family
ISU54_RS02205	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISU54_RS02210	COG4575	ribosome binding
ISU54_RS02225	COG0586	Pfam SNARE associated Golgi protein
ISU54_RS02240	COG2271	Major facilitator Superfamily
ISU54_RS02255	COG2721	sulfolactate sulfo-lyase activity
ISU54_RS02275	COG0673	inositol 2-dehydrogenase activity
ISU54_RS02280	COG1451	nucleotide metabolic process
ISU54_RS02295	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISU54_RS02295	COG1902	pentaerythritol trinitrate reductase activity
ISU54_RS02300	COG3247	response to pH
ISU54_RS02315	COG4245	von Willebrand factor, type A
ISU54_RS02330	COG4245	von Willebrand factor, type A
ISU54_RS02335	COG2831	hemolysin activation secretion protein
ISU54_RS02340	COG3210	domain, Protein
ISU54_RS02370	COG3210	domain, Protein
ISU54_RS02375	COG3210	domain, Protein
ISU54_RS02395	COG3842	ATPase activity
ISU54_RS02400	COG3459	Glycosyltransferase 36 associated
ISU54_RS02405	COG1609	Transcriptional regulator
ISU54_RS02410	COG2182	Extracellular solute-binding protein
ISU54_RS02420	COG0395	ABC-type sugar transport system, permease component
ISU54_RS02440	COG1289	transmembrane transporter activity
ISU54_RS02460	COG0436	Aminotransferase
ISU54_RS02480	COG0251	oxidation-reduction process
ISU54_RS02550	COG0358	DNA primase activity
ISU54_RS02555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISU54_RS02570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISU54_RS02585	COG4991	sh3 domain protein
ISU54_RS02590	COG3025	triphosphatase activity
ISU54_RS02605	COG0531	amino acid
ISU54_RS02625	COG3384	dioxygenase
ISU54_RS02630	COG0754	glutathionylspermidine amidase activity
ISU54_RS02640	COG1538	Outer membrane efflux protein
ISU54_RS02645	COG0494	nUDIX hydrolase
ISU54_RS02650	COG3151	Protein conserved in bacteria
ISU54_RS02655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISU54_RS02660	COG3150	esterase
ISU54_RS02670	COG0583	DNA-binding transcription factor activity
ISU54_RS02675	COG2249	NAD(P)H dehydrogenase (quinone) activity
ISU54_RS02685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISU54_RS02695	COG2132	Multicopper oxidase
ISU54_RS02705	COG0656	L-ascorbic acid biosynthetic process
ISU54_RS02715	COG1979	alcohol dehydrogenase
ISU54_RS02720	COG2207	Transcriptional regulator
ISU54_RS02725	COG0586	Pfam SNARE associated Golgi protein
ISU54_RS02730	COG0626	cystathionine gamma-synthase activity
ISU54_RS02735	COG0811	peptide transport
ISU54_RS02740	COG0848	biopolymer transport protein
ISU54_RS02790	COG4964	Belongs to the GSP D family
ISU54_RS02795	COG4964	Belongs to the GSP D family
ISU54_RS02830	COG4592	Periplasmic binding protein
ISU54_RS02850	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU54_RS02855	COG1684	flagellar biosynthetic protein fliR
ISU54_RS02860	COG1987	bacterial-type flagellum assembly
ISU54_RS02885	COG1677	Flagellar hook-basal body complex protein FliE
ISU54_RS02925	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ISU54_RS02930	COG1815	bacterial-type flagellum-dependent cell motility
ISU54_RS02935	COG1558	bacterial-type flagellum-dependent cell motility
ISU54_RS02940	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ISU54_RS02945	COG1749	Flagellar hook protein flgE
ISU54_RS02950	COG4787	bacterial-type flagellum-dependent cell motility
ISU54_RS02955	COG4786	Flagellar basal body rod
ISU54_RS02965	COG1706	bacterial-type flagellum-dependent cell motility
ISU54_RS02975	COG1256	bacterial-type flagellum assembly
ISU54_RS02995	COG3710	Transcriptional regulator
ISU54_RS03020	COG0471	metal ion transport
ISU54_RS03045	COG3501	Rhs element vgr protein
ISU54_RS03060	COG2610	gluconate transmembrane transporter activity
ISU54_RS03075	COG1132	(ABC) transporter
ISU54_RS03080	COG1132	(ABC) transporter
ISU54_RS03080	COG2375	cellular response to nickel ion
ISU54_RS03105	COG2226	methyltransferase
ISU54_RS03105	COG3433	isochorismatase activity
ISU54_RS03105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU54_RS03115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU54_RS03115	COG3433	isochorismatase activity
ISU54_RS03115	COG2226	methyltransferase
ISU54_RS03135	COG4771	TonB-dependent receptor
ISU54_RS03140	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU54_RS03145	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISU54_RS03190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU54_RS03200	COG5001	Diguanylate cyclase
ISU54_RS03210	COG2211	Major facilitator Superfamily
ISU54_RS03260	COG2771	luxR family
ISU54_RS03265	COG3916	Acyl-homoserine-lactone synthase
ISU54_RS03385	COG1982	Orn Lys Arg decarboxylase major
ISU54_RS03390	COG1879	ABC-type sugar transport system periplasmic component
ISU54_RS03395	COG1129	ABC transporter
ISU54_RS03400	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS03405	COG4774	siderophore transport
ISU54_RS03425	COG1194	a g-specific adenine glycosylase
ISU54_RS03435	COG3171	Protein conserved in bacteria
ISU54_RS03460	COG3064	Membrane
ISU54_RS03460	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ISU54_RS03460	COG1073	alpha beta
ISU54_RS03465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU54_RS03470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ISU54_RS03480	COG0762	integral membrane protein
ISU54_RS03485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISU54_RS03490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISU54_RS03495	COG2805	Type II/IV secretion system protein
ISU54_RS03505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU54_RS03520	COG0189	ligase activity
ISU54_RS03525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISU54_RS03530	COG2356	endonuclease I
ISU54_RS03545	COG1166	arginine decarboxylase activity
ISU54_RS03560	COG0501	Belongs to the peptidase M48B family
ISU54_RS03565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISU54_RS03585	COG0191	fructose-bisphosphate aldolase activity
ISU54_RS03620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISU54_RS03630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISU54_RS03650	COG0006	proline dipeptidase activity
ISU54_RS03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU54_RS03660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU54_RS03705	COG1272	protein, Hemolysin III
ISU54_RS03730	COG0745	RESPONSE REGULATOR receiver
ISU54_RS03735	COG2205	protein histidine kinase activity
ISU54_RS03740	COG4452	Inner membrane protein CreD
ISU54_RS03745	COG0716	FMN binding
ISU54_RS03750	COG4974	Belongs to the 'phage' integrase family
ISU54_RS03755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU54_RS03760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISU54_RS03780	COG0582	viral genome integration into host DNA
ISU54_RS03805	COG2944	sequence-specific DNA binding
ISU54_RS03895	COG1695	Transcriptional regulator
ISU54_RS03900	COG0791	NLP P60 protein
ISU54_RS03910	COG1879	ABC-type sugar transport system periplasmic component
ISU54_RS03915	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS03920	COG1129	ABC transporter
ISU54_RS03930	COG2182	Extracellular solute-binding protein
ISU54_RS03935	COG1175	transmembrane transport
ISU54_RS03940	COG3833	ABC-type maltose transport systems, permease component
ISU54_RS03945	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISU54_RS03950	COG1874	Beta-galactosidase
ISU54_RS03955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU54_RS03955	COG1263	PTS System
ISU54_RS03975	COG2271	Major facilitator Superfamily
ISU54_RS04000	COG3119	arylsulfatase activity
ISU54_RS04005	COG0641	radical SAM
ISU54_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS04025	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS04030	COG3716	PTS system mannose fructose sorbose family IID component
ISU54_RS04035	COG3715	PTS system
ISU54_RS04040	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU54_RS04045	COG2222	sugar isomerase
ISU54_RS04055	COG1349	DNA-binding transcription factor activity
ISU54_RS04060	COG3119	arylsulfatase activity
ISU54_RS04100	COG0288	reversible hydration of carbon dioxide
ISU54_RS04120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU54_RS04140	COG2165	general secretion pathway protein
ISU54_RS04185	COG0840	transmembrane signaling receptor activity
ISU54_RS04200	COG0583	DNA-binding transcription factor activity
ISU54_RS04205	COG2814	Major facilitator Superfamily
ISU54_RS04210	COG0583	DNA-binding transcription factor activity
ISU54_RS04220	COG1609	Transcriptional regulator
ISU54_RS04250	COG0667	Aldo Keto reductase
ISU54_RS04300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISU54_RS04310	COG1074	ATP-dependent DNA helicase activity
ISU54_RS04315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISU54_RS04325	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU54_RS04340	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISU54_RS04345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISU54_RS04350	COG2166	iron-sulfur cluster assembly
ISU54_RS04355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISU54_RS04365	COG0583	DNA-binding transcription factor activity
ISU54_RS04370	COG2363	Small membrane protein
ISU54_RS04395	COG1611	Belongs to the LOG family
ISU54_RS04415	COG3098	single-species biofilm formation
ISU54_RS04420	COG0564	pseudouridine synthase activity
ISU54_RS04480	COG0575	Belongs to the CDS family
ISU54_RS04485	COG0750	zinc metalloprotease
ISU54_RS04500	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ISU54_RS04525	COG0587	DNA-directed DNA polymerase activity
ISU54_RS04535	COG0346	lactoylglutathione lyase activity
ISU54_RS04540	COG0037	tRNA processing
ISU54_RS04550	COG4568	rho-dependent transcription termination
ISU54_RS04560	COG4681	YaeQ
ISU54_RS04570	COG3015	lipoprotein NlpE involved in copper resistance
ISU54_RS04580	COG1720	tRNA m6t6A37 methyltransferase activity
ISU54_RS04590	COG1464	Belongs to the NlpA lipoprotein family
ISU54_RS04595	COG2011	ABC-type metal ion transport system permease component
ISU54_RS04605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU54_RS04635	COG0656	L-ascorbic acid biosynthetic process
ISU54_RS04650	COG1388	LysM domain
ISU54_RS04650	COG0741	lytic transglycosylase activity
ISU54_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU54_RS04660	COG2226	methyltransferase
ISU54_RS04680	COG1953	Uracil, thiamine, allantoin
ISU54_RS04705	COG3657	addiction module killer protein
ISU54_RS04755	COG0582	viral genome integration into host DNA
ISU54_RS04775	COG2867	negative regulation of translational initiation
ISU54_RS04785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU54_RS04790	COG0497	DNA recombination
ISU54_RS04795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ISU54_RS04810	COG2009	succinate dehydrogenase
ISU54_RS04815	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISU54_RS04820	COG1053	succinate dehydrogenase
ISU54_RS04830	COG0567	Dehydrogenase, E1 component
ISU54_RS04835	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU54_RS04845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISU54_RS04850	COG1271	oxidase subunit
ISU54_RS04855	COG1294	oxidase, subunit
ISU54_RS04860	COG4890	Cyd operon protein YbgT
ISU54_RS04865	COG3790	cyd operon protein YbgE
ISU54_RS04870	COG0824	Thioesterase
ISU54_RS04875	COG0811	peptide transport
ISU54_RS04880	COG0848	biopolymer transport protein
ISU54_RS04885	COG3064	Membrane
ISU54_RS04885	COG3064	Membrane
ISU54_RS04895	COG2885	chlorophyll binding
ISU54_RS04900	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISU54_RS04930	COG1230	cation diffusion facilitator family transporter
ISU54_RS04935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU54_RS04950	COG2017	converts alpha-aldose to the beta-anomer
ISU54_RS04965	COG1085	galactose-1-phosphate uridylyltransferase
ISU54_RS04970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ISU54_RS04980	COG1119	ATPase activity
ISU54_RS04985	COG2005	Transcriptional regulator
ISU54_RS04985	COG3585	molybdate ion transport
ISU54_RS04995	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISU54_RS05000	COG4149	molybdate abc transporter
ISU54_RS05010	COG0561	phosphatase activity
ISU54_RS05035	COG2226	methyltransferase
ISU54_RS05045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISU54_RS05055	COG4628	conserved protein (DUF2132)
ISU54_RS05060	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ISU54_RS05065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ISU54_RS05075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISU54_RS05080	COG0314	molybdopterin synthase activity
ISU54_RS05085	COG0670	Belongs to the BI1 family
ISU54_RS05100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU54_RS05110	COG1686	Belongs to the peptidase S11 family
ISU54_RS05115	COG0277	FAD linked oxidase domain protein
ISU54_RS05135	COG2261	transglycosylase associated protein
ISU54_RS05145	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISU54_RS05160	COG4807	Protein conserved in bacteria
ISU54_RS05180	COG1122	ATPase activity
ISU54_RS05200	COG2897	thiosulfate sulfurtransferase activity
ISU54_RS05205	COG1732	Glycine betaine
ISU54_RS05210	COG1732	Glycine betaine
ISU54_RS05215	COG1174	glycine betaine transport
ISU54_RS05220	COG1125	glycine betaine transport
ISU54_RS05225	COG1174	glycine betaine transport
ISU54_RS05230	COG0531	amino acid
ISU54_RS05235	COG1982	Orn Lys Arg decarboxylase major
ISU54_RS05245	COG0697	spore germination
ISU54_RS05270	COG0814	amino acid
ISU54_RS05285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU54_RS05310	COG0784	Response regulator, receiver
ISU54_RS05310	COG2205	protein histidine kinase activity
ISU54_RS05320	COG2198	Histidine kinase
ISU54_RS05320	COG0642	Histidine kinase
ISU54_RS05325	COG2198	Histidine kinase
ISU54_RS05325	COG0642	Histidine kinase
ISU54_RS05330	COG2223	nitrite transmembrane transporter activity
ISU54_RS05355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISU54_RS05395	COG3395	kinase activity
ISU54_RS05405	COG1349	DNA-binding transcription factor activity
ISU54_RS05410	COG3622	Belongs to the hyi family
ISU54_RS05430	COG4386	tail sheath protein
ISU54_RS05470	COG3299	homolog of phage Mu protein gp47
ISU54_RS05490	COG1737	Transcriptional regulator
ISU54_RS05495	COG2723	6-phospho-beta-galactosidase activity
ISU54_RS05515	COG3157	Type VI secretion system effector, Hcp
ISU54_RS05530	COG3083	sulfuric ester hydrolase activity
ISU54_RS05535	COG3082	Protein of unknown function (DUF1414)
ISU54_RS05555	COG1061	Type III restriction enzyme res subunit
ISU54_RS05560	COG1187	pseudouridine synthase activity
ISU54_RS05565	COG2814	Major facilitator Superfamily
ISU54_RS05575	COG4172	Belongs to the ABC transporter superfamily
ISU54_RS05580	COG4239	(ABC) transporter, permease
ISU54_RS05585	COG4174	ABC transporter (Permease)
ISU54_RS05590	COG4166	transmembrane transport
ISU54_RS05595	COG2200	EAL domain
ISU54_RS05600	COG0791	NLP P60 protein
ISU54_RS05605	COG0671	phosphoesterase, PA-phosphatase related
ISU54_RS05610	COG0523	cobalamin synthesis protein
ISU54_RS05615	COG2186	Transcriptional regulator
ISU54_RS05620	COG0246	Mannitol dehydrogenase
ISU54_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS05680	COG1129	ABC transporter
ISU54_RS05690	COG0494	nUDIX hydrolase
ISU54_RS05700	COG1105	Belongs to the carbohydrate kinase PfkB family
ISU54_RS05705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU54_RS05705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU54_RS05705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISU54_RS05710	COG3710	Transcriptional regulator
ISU54_RS05725	COG3121	Chaperone
ISU54_RS05730	COG3188	usher protein
ISU54_RS05740	COG2855	membrane
ISU54_RS05745	COG0583	DNA-binding transcription factor activity
ISU54_RS05750	COG0833	amino acid
ISU54_RS05760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS05770	COG4771	TonB-dependent receptor
ISU54_RS05775	COG0625	glutathione transferase activity
ISU54_RS05800	COG2011	ABC-type metal ion transport system permease component
ISU54_RS05805	COG1686	Belongs to the peptidase S11 family
ISU54_RS05810	COG0814	amino acid
ISU54_RS05815	COG1349	DNA-binding transcription factor activity
ISU54_RS05825	COG0671	phosphoesterase, PA-phosphatase related
ISU54_RS05855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISU54_RS05860	COG3842	ATPase activity
ISU54_RS05865	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU54_RS05870	COG1177	transmembrane transport
ISU54_RS05885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS05910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS05915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS05920	COG1120	ATPase activity
ISU54_RS05945	COG4160	amino acid transport
ISU54_RS05950	COG4215	(ABC) transporter
ISU54_RS05955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS05960	COG1126	abc transporter atp-binding protein
ISU54_RS05965	COG1605	Chorismate mutase
ISU54_RS05975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU54_RS05980	COG0702	epimerase
ISU54_RS05985	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISU54_RS05995	COG0028	Belongs to the TPP enzyme family
ISU54_RS06000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU54_RS06010	COG2431	L-lysine efflux transmembrane transporter activity
ISU54_RS06015	COG3593	DNA synthesis involved in DNA repair
ISU54_RS06020	COG2990	Protein conserved in bacteria
ISU54_RS06025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU54_RS06035	COG1278	Cold shock
ISU54_RS06045	COG0542	response to heat
ISU54_RS06055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ISU54_RS06065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISU54_RS06075	COG0492	ferredoxin-NADP+ reductase activity
ISU54_RS06085	COG1674	ftsk spoiiie
ISU54_RS06085	COG3107	peptidoglycan biosynthetic process
ISU54_RS06095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISU54_RS06125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISU54_RS06135	COG1882	Formate acetyltransferase
ISU54_RS06140	COG2116	formate transmembrane transporter activity
ISU54_RS06145	COG1944	ATP diphosphatase activity
ISU54_RS06150	COG0252	asparaginase activity
ISU54_RS06155	COG5295	Hep Hag repeat protein
ISU54_RS06155	COG5295	Hep Hag repeat protein
ISU54_RS06180	COG0539	negative regulation of cytoplasmic translation
ISU54_RS06190	COG2333	competence protein COMEC
ISU54_RS06190	COG0658	competence protein
ISU54_RS06205	COG5383	Protein conserved in bacteria
ISU54_RS06210	COG1278	Cold shock
ISU54_RS06225	COG3173	Aminoglycoside phosphotransferase
ISU54_RS06230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISU54_RS06255	COG2989	Protein conserved in bacteria
ISU54_RS06260	COG3108	Peptidase M15
ISU54_RS06265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU54_RS06275	COG1448	Aminotransferase
ISU54_RS06295	COG0308	aminopeptidase N
ISU54_RS06310	COG3217	Mosc domain protein beta barrel domain protein
ISU54_RS06310	COG0633	Ferredoxin
ISU54_RS06320	COG0488	(ABC) transporter
ISU54_RS06325	COG2995	paraquat-inducible protein a
ISU54_RS06330	COG3008	intermembrane lipid transfer
ISU54_RS06330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU54_RS06335	COG3009	Protein conserved in bacteria
ISU54_RS06340	COG3130	regulation of translation
ISU54_RS06380	COG1067	ATP-dependent peptidase activity
ISU54_RS06405	COG3070	regulator of competence-specific genes
ISU54_RS06410	COG1289	transmembrane transporter activity
ISU54_RS06415	COG3304	Inner membrane component domain
ISU54_RS06420	COG0210	DNA helicase
ISU54_RS06435	COG1832	CoA-binding protein
ISU54_RS06455	COG2920	part of a sulfur-relay system
ISU54_RS06480	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS06490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ISU54_RS06495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU54_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS06505	COG3425	synthase
ISU54_RS06515	COG1024	Enoyl-CoA hydratase
ISU54_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS06530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ISU54_RS06535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISU54_RS06665	COG0488	(ABC) transporter
ISU54_RS06675	COG3328	transposase activity
ISU54_RS06685	COG0303	'Molybdopterin
ISU54_RS06695	COG1136	(ABC) transporter
ISU54_RS06725	COG0583	DNA-binding transcription factor activity
ISU54_RS06730	COG0477	Major facilitator Superfamily
ISU54_RS06740	COG2311	Membrane
ISU54_RS06755	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS06760	COG2949	membrane
ISU54_RS06775	COG1346	cytolysis
ISU54_RS06785	COG2814	Major facilitator Superfamily
ISU54_RS06815	COG0489	protein tyrosine kinase activity
ISU54_RS06830	COG2982	Protein involved in outer membrane biogenesis
ISU54_RS06835	COG1253	flavin adenine dinucleotide binding
ISU54_RS06840	COG4114	ferric iron reductase
ISU54_RS06845	COG0076	glutamate decarboxylase activity
ISU54_RS06850	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ISU54_RS06865	COG1120	ATPase activity
ISU54_RS06870	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS06875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS06880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU54_RS06895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU54_RS06900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU54_RS06910	COG0140	phosphoribosyl-ATP diphosphatase activity
ISU54_RS06910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ISU54_RS06930	COG0131	Imidazoleglycerol-phosphate dehydratase
ISU54_RS06930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU54_RS06940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ISU54_RS06955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU54_RS06970	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS06975	COG1129	ABC transporter
ISU54_RS06980	COG1129	ABC transporter
ISU54_RS06985	COG0371	Dehydrogenase
ISU54_RS06990	COG0531	amino acid
ISU54_RS07000	COG2925	Exonuclease
ISU54_RS07015	COG3328	transposase activity
ISU54_RS07020	COG1470	cell adhesion involved in biofilm formation
ISU54_RS07020	COG1388	LysM domain
ISU54_RS07025	COG2271	Major facilitator Superfamily
ISU54_RS07030	COG3011	Protein conserved in bacteria
ISU54_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS07045	COG4948	Mandelate Racemase Muconate Lactonizing
ISU54_RS07060	COG0534	Mate efflux family protein
ISU54_RS07080	COG3122	Protein conserved in bacteria
ISU54_RS07105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISU54_RS07125	COG2223	nitrite transmembrane transporter activity
ISU54_RS07130	COG3328	transposase activity
ISU54_RS07175	COG1132	(ABC) transporter
ISU54_RS07185	COG2207	Transcriptional regulator
ISU54_RS07220	COG1113	amino acid transport
ISU54_RS07240	COG1496	oxidoreductase activity
ISU54_RS07245	COG2226	methyltransferase
ISU54_RS07275	COG3716	PTS system mannose fructose sorbose family IID component
ISU54_RS07280	COG3715	PTS system
ISU54_RS07285	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU54_RS07285	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS07290	COG1253	flavin adenine dinucleotide binding
ISU54_RS07295	COG1846	Transcriptional regulator
ISU54_RS07310	COG1012	belongs to the aldehyde dehydrogenase family
ISU54_RS07315	COG3384	dioxygenase
ISU54_RS07325	COG3971	2-oxopent-4-enoate hydratase activity
ISU54_RS07340	COG2368	4-hydroxyphenylacetate
ISU54_RS07345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISU54_RS07350	COG1760	l-serine dehydratase
ISU54_RS07375	COG0513	Belongs to the DEAD box helicase family
ISU54_RS07380	COG3141	response to X-ray
ISU54_RS07395	COG1770	oligopeptidase
ISU54_RS07410	COG1528	Iron-storage protein
ISU54_RS07415	COG2372	response to copper ion
ISU54_RS07440	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU54_RS07445	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU54_RS07470	COG3418	PFAM FlgN family protein
ISU54_RS07475	COG2747	anti-sigma28 factor FlgM
ISU54_RS07485	COG1815	bacterial-type flagellum-dependent cell motility
ISU54_RS07490	COG1558	bacterial-type flagellum-dependent cell motility
ISU54_RS07530	COG1256	bacterial-type flagellum assembly
ISU54_RS07540	COG2390	Transcriptional regulator
ISU54_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS07545	COG3347	Dehydrogenase
ISU54_RS07550	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS07560	COG1129	ABC transporter
ISU54_RS07565	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS07570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU54_RS07590	COG1987	bacterial-type flagellum assembly
ISU54_RS07615	COG1580	Controls the rotational direction of flagella during chemotaxis
ISU54_RS07630	COG1157	protein secretion by the type III secretion system
ISU54_RS07650	COG1677	Flagellar hook-basal body complex protein FliE
ISU54_RS07670	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISU54_RS07675	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISU54_RS07680	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ISU54_RS07710	COG1191	sigma factor activity
ISU54_RS07725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS07730	COG0765	amino acid transport
ISU54_RS07735	COG1126	abc transporter atp-binding protein
ISU54_RS07750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU54_RS07750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU54_RS07750	COG0506	proline dehydrogenase activity
ISU54_RS07765	COG0672	)-iron permease
ISU54_RS07770	COG2822	iron ion transport
ISU54_RS07790	COG1113	amino acid transport
ISU54_RS07810	COG3136	membrane protein required for alginate biosynthesis
ISU54_RS07820	COG2197	response regulator
ISU54_RS07940	COG2188	Transcriptional regulator
ISU54_RS07945	COG0673	inositol 2-dehydrogenase activity
ISU54_RS07955	COG1175	transmembrane transport
ISU54_RS07960	COG0395	ABC-type sugar transport system, permease component
ISU54_RS07965	COG3842	ATPase activity
ISU54_RS08025	COG4771	TonB-dependent receptor
ISU54_RS08030	COG1021	2,3-dihydroxybenzoate-AMP ligase
ISU54_RS08050	COG2226	methyltransferase
ISU54_RS08050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU54_RS08050	COG3433	isochorismatase activity
ISU54_RS08065	COG1132	(ABC) transporter
ISU54_RS08070	COG2814	Major facilitator Superfamily
ISU54_RS08075	COG1169	isochorismate synthase
ISU54_RS08080	COG0582	viral genome integration into host DNA
ISU54_RS08090	COG3121	Chaperone
ISU54_RS08100	COG3188	usher protein
ISU54_RS08115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS08115	COG2205	protein histidine kinase activity
ISU54_RS08125	COG0427	acetyl-CoA hydrolase
ISU54_RS08130	COG2030	dehydratase
ISU54_RS08155	COG2814	Major facilitator Superfamily
ISU54_RS08170	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU54_RS08175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU54_RS08185	COG1349	DNA-binding transcription factor activity
ISU54_RS08195	COG2066	Belongs to the glutaminase family
ISU54_RS08210	COG0672	)-iron permease
ISU54_RS08225	COG0577	efflux transmembrane transporter activity
ISU54_RS08225	COG1136	(ABC) transporter
ISU54_RS08235	COG0577	efflux transmembrane transporter activity
ISU54_RS08235	COG1136	(ABC) transporter
ISU54_RS08255	COG0006	proline dipeptidase activity
ISU54_RS08260	COG0457	Tetratricopeptide repeat
ISU54_RS08265	COG1649	PFAM Uncharacterised BCR, COG1649
ISU54_RS08265	COG0726	polysaccharide deacetylase
ISU54_RS08270	COG1215	transferase activity, transferring glycosyl groups
ISU54_RS08275	COG3658	cytochrome
ISU54_RS08290	COG1702	phosphate starvation-inducible protein PhoH
ISU54_RS08295	COG0387	Pfam Sodium calcium exchanger
ISU54_RS08300	COG3850	Histidine kinase
ISU54_RS08310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ISU54_RS08375	COG0402	S-adenosylhomocysteine deaminase activity
ISU54_RS08390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU54_RS08395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU54_RS08400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU54_RS08445	COG3328	transposase activity
ISU54_RS08465	COG0500	methyltransferase
ISU54_RS08510	COG5002	protein histidine kinase activity
ISU54_RS08560	COG0012	GTP binding
ISU54_RS08575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ISU54_RS08600	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU54_RS08620	COG0659	secondary active sulfate transmembrane transporter activity
ISU54_RS08640	COG3833	ABC-type maltose transport systems, permease component
ISU54_RS08645	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU54_RS08665	COG0584	glycerophosphoryl diester phosphodiesterase
ISU54_RS08670	COG1940	carbohydrate kinase activity
ISU54_RS08685	COG3381	protein complex oligomerization
ISU54_RS08700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU54_RS08710	COG0728	peptidoglycan biosynthetic process
ISU54_RS08730	COG3102	Protein conserved in bacteria
ISU54_RS08750	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISU54_RS08755	COG1801	Protein of unknown function DUF72
ISU54_RS08765	COG0494	nUDIX hydrolase
ISU54_RS08790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU54_RS08800	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISU54_RS08805	COG0739	heme binding
ISU54_RS08810	COG1560	Kdo2-lipid A biosynthetic process
ISU54_RS08820	COG0469	pyruvate kinase activity
ISU54_RS08825	COG1737	Transcriptional regulator
ISU54_RS08830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISU54_RS08835	COG0800	Aldolase
ISU54_RS08850	COG0251	oxidation-reduction process
ISU54_RS08855	COG1199	ATP-dependent helicase activity
ISU54_RS08865	COG3065	identical protein binding
ISU54_RS08875	COG0318	PFAM AMP-dependent synthetase and ligase
ISU54_RS08880	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ISU54_RS08885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ISU54_RS08890	COG2894	cell division
ISU54_RS08905	COG2951	lytic endotransglycosylase activity
ISU54_RS08910	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISU54_RS08920	COG0582	viral genome integration into host DNA
ISU54_RS09020	COG3328	transposase activity
ISU54_RS09180	COG3328	transposase activity
ISU54_RS09190	COG1104	cysteine desulfurase activity
ISU54_RS09220	COG2719	SpoVR family
ISU54_RS09230	COG2814	Major facilitator Superfamily
ISU54_RS09240	COG0583	DNA-binding transcription factor activity
ISU54_RS09255	COG2766	serine protein kinase
ISU54_RS09260	COG3713	MltA-interacting MipA family protein
ISU54_RS09280	COG3139	Protein of unknown function (DUF1315)
ISU54_RS09285	COG1335	isochorismatase
ISU54_RS09290	COG0252	asparaginase activity
ISU54_RS09295	COG0616	signal peptide processing
ISU54_RS09300	COG0778	Nitroreductase
ISU54_RS09305	COG0709	Synthesizes selenophosphate from selenide and ATP
ISU54_RS09310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISU54_RS09320	COG0494	nUDIX hydrolase
ISU54_RS09325	COG0708	Exodeoxyribonuclease III
ISU54_RS09330	COG0583	DNA-binding transcription factor activity
ISU54_RS09350	COG3328	transposase activity
ISU54_RS09355	COG0788	formyltetrahydrofolate deformylase activity
ISU54_RS09365	COG0745	RESPONSE REGULATOR receiver
ISU54_RS09400	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISU54_RS09405	COG2205	protein histidine kinase activity
ISU54_RS09410	COG0745	RESPONSE REGULATOR receiver
ISU54_RS09420	COG0531	amino acid
ISU54_RS09430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISU54_RS09435	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISU54_RS09440	COG0589	response to stress
ISU54_RS09445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISU54_RS09450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU54_RS09465	COG1011	Hydrolase
ISU54_RS09470	COG0440	acetolactate synthase activity
ISU54_RS09475	COG0028	Belongs to the TPP enzyme family
ISU54_RS09505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISU54_RS09515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU54_RS09535	COG1609	Transcriptional regulator
ISU54_RS09540	COG0038	chloride channel
ISU54_RS09545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISU54_RS09550	COG1940	carbohydrate kinase activity
ISU54_RS09555	COG0583	DNA-binding transcription factor activity
ISU54_RS09560	COG2814	Major facilitator Superfamily
ISU54_RS09570	COG0114	fumarate hydratase activity
ISU54_RS09580	COG5339	Protein conserved in bacteria
ISU54_RS09590	COG0385	Bile acid
ISU54_RS09595	COG0673	inositol 2-dehydrogenase activity
ISU54_RS09605	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS09610	COG1129	ABC transporter
ISU54_RS09615	COG1879	ABC-type sugar transport system periplasmic component
ISU54_RS09630	COG2274	protein secretion by the type I secretion system
ISU54_RS09635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU54_RS09645	COG2274	protein secretion by the type I secretion system
ISU54_RS09675	COG2207	Transcriptional regulator
ISU54_RS09675	COG3708	Transcriptional regulator
ISU54_RS09680	COG4658	electron transport chain
ISU54_RS09685	COG4659	FMN binding
ISU54_RS09695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISU54_RS09700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU54_RS09705	COG2271	Major facilitator Superfamily
ISU54_RS09715	COG1966	Carbon starvation protein
ISU54_RS09720	COG2879	small protein
ISU54_RS09725	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISU54_RS09745	COG0023	Translation Initiation Factor
ISU54_RS09760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISU54_RS09765	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISU54_RS09770	COG0671	phosphoesterase, PA-phosphatase related
ISU54_RS09780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISU54_RS09790	COG0583	DNA-binding transcription factor activity
ISU54_RS09810	COG0616	signal peptide processing
ISU54_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS09825	COG1187	pseudouridine synthase activity
ISU54_RS09830	COG0009	L-threonylcarbamoyladenylate synthase
ISU54_RS09850	COG0512	Glutamine amidotransferase of anthranilate synthase
ISU54_RS09860	COG0134	indole-3-glycerol-phosphate synthase activity
ISU54_RS09860	COG0135	phosphoribosylanthranilate isomerase activity
ISU54_RS09880	COG3047	cAMP biosynthetic process
ISU54_RS09915	COG3328	transposase activity
ISU54_RS09920	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISU54_RS09925	COG2350	Protein conserved in bacteria
ISU54_RS09970	COG4608	Belongs to the ABC transporter superfamily
ISU54_RS09975	COG0444	Belongs to the ABC transporter superfamily
ISU54_RS09980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU54_RS09985	COG0601	transmembrane transport
ISU54_RS09995	COG2095	MarC family integral membrane protein
ISU54_RS10000	COG1454	alcohol dehydrogenase
ISU54_RS10000	COG1012	belongs to the aldehyde dehydrogenase family
ISU54_RS10040	COG3591	Belongs to the peptidase S1B family
ISU54_RS10055	COG1643	Atp-dependent helicase
ISU54_RS10065	COG2390	Transcriptional regulator
ISU54_RS10070	COG0246	Mannitol dehydrogenase
ISU54_RS10075	COG3784	Protein of unknown function (DUF1318)
ISU54_RS10085	COG2911	Protein conserved in bacteria
ISU54_RS10090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU54_RS10095	COG3187	Heat shock protein
ISU54_RS10100	COG3042	response to heat
ISU54_RS10105	COG1285	pathogenesis
ISU54_RS10115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISU54_RS10115	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISU54_RS10115	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISU54_RS10115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU54_RS10125	COG0657	acetylesterase activity
ISU54_RS10140	COG4166	transmembrane transport
ISU54_RS10145	COG2866	Carboxypeptidase
ISU54_RS10150	COG4948	Mandelate Racemase Muconate Lactonizing
ISU54_RS10155	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISU54_RS10170	COG5642	Protein of unknown function (DUF2384)
ISU54_RS10175	COG5654	RES domain protein
ISU54_RS10185	COG3106	COG3106 Predicted ATPase
ISU54_RS10195	COG1983	PspC domain protein
ISU54_RS10205	COG1842	Phage shock protein A
ISU54_RS10210	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISU54_RS10220	COG4166	transmembrane transport
ISU54_RS10225	COG4168	peptide transport system, permease
ISU54_RS10230	COG4171	peptide transport system, permease
ISU54_RS10240	COG4172	Belongs to the ABC transporter superfamily
ISU54_RS10245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU54_RS10245	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU54_RS10250	COG3104	oligopeptide transport
ISU54_RS10265	COG0625	glutathione transferase activity
ISU54_RS10285	COG3895	Periplasmic Protein
ISU54_RS10295	COG3133	Outer membrane lipoprotein
ISU54_RS10305	COG2194	sulfuric ester hydrolase activity
ISU54_RS10310	COG1309	transcriptional regulator
ISU54_RS10320	COG0346	lactoylglutathione lyase activity
ISU54_RS10325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISU54_RS10335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISU54_RS10340	COG0791	NLP P60 protein
ISU54_RS10360	COG0583	DNA-binding transcription factor activity
ISU54_RS10365	COG2814	Major facilitator Superfamily
ISU54_RS10370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISU54_RS10375	COG0307	riboflavin synthase, alpha
ISU54_RS10430	COG1376	ErfK ybiS ycfS ynhG family protein
ISU54_RS10430	COG1388	LysM domain
ISU54_RS10445	COG0719	Fe-S assembly protein
ISU54_RS10450	COG0396	ATPase activity
ISU54_RS10455	COG0719	Fe-S assembly protein
ISU54_RS10460	COG0316	Belongs to the HesB IscA family
ISU54_RS10465	COG2050	protein possibly involved in aromatic compounds catabolism
ISU54_RS10470	COG0277	FAD linked oxidase domain protein
ISU54_RS10470	COG0247	lactate metabolic process
ISU54_RS10475	COG0628	permease
ISU54_RS10485	COG0574	Belongs to the PEP-utilizing enzyme family
ISU54_RS10485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU54_RS10510	COG0791	NLP P60 protein
ISU54_RS10560	COG0386	Belongs to the glutathione peroxidase family
ISU54_RS10575	COG0776	regulation of translation
ISU54_RS10580	COG0072	phenylalanine-tRNA ligase activity
ISU54_RS10580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISU54_RS10615	COG4249	Peptidase C14 caspase catalytic subunit p20
ISU54_RS10635	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISU54_RS10640	COG1121	(ABC) transporter
ISU54_RS10645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU54_RS10650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU54_RS10660	COG3001	Fructosamine kinase
ISU54_RS10670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU54_RS10675	COG3328	transposase activity
ISU54_RS10680	COG1917	Cupin 2, conserved barrel domain protein
ISU54_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS10700	COG1175	transmembrane transport
ISU54_RS10705	COG0395	ABC-type sugar transport system, permease component
ISU54_RS10710	COG3842	ATPase activity
ISU54_RS10715	COG1653	transport
ISU54_RS10720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU54_RS10725	COG1988	membrane-bound metal-dependent
ISU54_RS10730	COG1823	symporter activity
ISU54_RS10735	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU54_RS10745	COG0823	Involved in the tonB-independent uptake of proteins
ISU54_RS10750	COG2814	Major facilitator Superfamily
ISU54_RS10755	COG3121	Chaperone
ISU54_RS10770	COG3121	Chaperone
ISU54_RS10775	COG3539	Fimbrial protein
ISU54_RS10785	COG0793	Belongs to the peptidase S41A family
ISU54_RS10795	COG1956	GAF domain-containing protein
ISU54_RS10800	COG2995	paraquat-inducible protein a
ISU54_RS10805	COG3008	intermembrane lipid transfer
ISU54_RS10825	COG3121	Chaperone
ISU54_RS10880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISU54_RS10890	COG5295	Hep Hag repeat protein
ISU54_RS10900	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU54_RS10905	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ISU54_RS10910	COG0745	RESPONSE REGULATOR receiver
ISU54_RS10920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ISU54_RS10925	COG0840	transmembrane signaling receptor activity
ISU54_RS10930	COG0840	transmembrane signaling receptor activity
ISU54_RS10950	COG2964	Protein conserved in bacteria
ISU54_RS10960	COG0251	oxidation-reduction process
ISU54_RS10965	COG2271	Major facilitator Superfamily
ISU54_RS10970	COG0835	chemotaxis
ISU54_RS10975	COG2198	Histidine kinase
ISU54_RS10975	COG0643	Histidine kinase
ISU54_RS10980	COG1360	Flagellar Motor Protein
ISU54_RS11005	COG1285	pathogenesis
ISU54_RS11030	COG3321	synthase
ISU54_RS11030	COG0604	alcohol dehydrogenase
ISU54_RS11030	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS11045	COG1522	sequence-specific DNA binding
ISU54_RS11070	COG1733	regulation of RNA biosynthetic process
ISU54_RS11075	COG0702	epimerase
ISU54_RS11080	COG0840	transmembrane signaling receptor activity
ISU54_RS11095	COG0538	isocitrate dehydrogenase activity
ISU54_RS11100	COG1187	pseudouridine synthase activity
ISU54_RS11120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISU54_RS11130	COG0745	RESPONSE REGULATOR receiver
ISU54_RS11140	COG2850	peptidyl-arginine hydroxylation
ISU54_RS11160	COG1940	carbohydrate kinase activity
ISU54_RS11165	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU54_RS11175	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU54_RS11180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISU54_RS11185	COG3134	Outer membrane lipoprotein
ISU54_RS11190	COG3328	transposase activity
ISU54_RS11205	COG1252	NADH dehydrogenase
ISU54_RS11215	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU54_RS11230	COG5633	Lipoprotein
ISU54_RS11235	COG0537	adenosine 5'-monophosphoramidase activity
ISU54_RS11240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISU54_RS11250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU54_RS11250	COG1263	PTS System
ISU54_RS11255	COG0084	hydrolase, TatD family'
ISU54_RS11260	COG0470	DNA polymerase III
ISU54_RS11270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISU54_RS11275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU54_RS11285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU54_RS11315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ISU54_RS11320	COG1399	metal-binding, possibly nucleic acid-binding protein
ISU54_RS11325	COG0424	maF-like protein
ISU54_RS11330	COG0564	pseudouridine synthase activity
ISU54_RS11335	COG1530	ribonuclease E activity
ISU54_RS11340	COG3328	transposase activity
ISU54_RS11360	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISU54_RS11370	COG3328	transposase activity
ISU54_RS11390	COG0628	permease
ISU54_RS11410	COG3916	Acyl-homoserine-lactone synthase
ISU54_RS11415	COG2771	luxR family
ISU54_RS11420	COG0583	DNA-binding transcription factor activity
ISU54_RS11430	COG0477	Major facilitator Superfamily
ISU54_RS11440	COG0667	Aldo Keto reductase
ISU54_RS11465	COG1203	CRISPR-associated helicase, Cas3
ISU54_RS11470	COG1518	maintenance of DNA repeat elements
ISU54_RS11475	COG0668	transmembrane transport
ISU54_RS11500	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ISU54_RS11505	COG0395	ABC-type sugar transport system, permease component
ISU54_RS11520	COG1609	Transcriptional regulator
ISU54_RS11530	COG3842	ATPase activity
ISU54_RS11540	COG3210	domain, Protein
ISU54_RS11580	COG3210	domain, Protein
ISU54_RS11585	COG2831	hemolysin activation secretion protein
ISU54_RS11590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU54_RS11600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU54_RS11610	COG0473	3-isopropylmalate dehydrogenase activity
ISU54_RS11615	COG0583	DNA-binding transcription factor activity
ISU54_RS11620	COG1609	Transcriptional regulator
ISU54_RS11625	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS11630	COG1129	ABC transporter
ISU54_RS11635	COG1879	ABC-type sugar transport system periplasmic component
ISU54_RS11640	COG1063	alcohol dehydrogenase
ISU54_RS11660	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISU54_RS11690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS11695	COG0765	amino acid transport
ISU54_RS11700	COG1126	abc transporter atp-binding protein
ISU54_RS11735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISU54_RS11750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ISU54_RS11765	COG1169	isochorismate synthase
ISU54_RS11775	COG4575	ribosome binding
ISU54_RS11780	COG0129	dihydroxy-acid dehydratase activity
ISU54_RS11795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU54_RS11800	COG1609	Transcriptional regulator
ISU54_RS11805	COG1649	PFAM Uncharacterised BCR, COG1649
ISU54_RS11820	COG3265	gluconokinase activity
ISU54_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS11830	COG2731	YhcH YjgK YiaL family protein
ISU54_RS11845	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU54_RS11850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISU54_RS11860	COG0839	Belongs to the complex I subunit 6 family
ISU54_RS11875	COG1034	ATP synthesis coupled electron transport
ISU54_RS11895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU54_RS11905	COG0583	DNA-binding transcription factor activity
ISU54_RS11910	COG0436	Aminotransferase
ISU54_RS11920	COG0490	domain, Protein
ISU54_RS11920	COG0471	metal ion transport
ISU54_RS11925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU54_RS11945	COG0280	phosphate acetyltransferase
ISU54_RS11945	COG0857	belongs to the CobB CobQ family
ISU54_RS11950	COG1609	Transcriptional regulator
ISU54_RS11965	COG3328	transposase activity
ISU54_RS11970	COG3037	sugar-specific permease SgaT UlaA
ISU54_RS11975	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISU54_RS11980	COG0622	Phosphoesterase
ISU54_RS11990	COG1090	epimerase
ISU54_RS11995	COG4598	ABC transporter
ISU54_RS12000	COG4160	amino acid transport
ISU54_RS12005	COG4215	(ABC) transporter
ISU54_RS12010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS12020	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISU54_RS12025	COG1286	toxin biosynthetic process
ISU54_RS12030	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISU54_RS12035	COG0285	dihydrofolate synthase activity
ISU54_RS12045	COG0586	Pfam SNARE associated Golgi protein
ISU54_RS12055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU54_RS12070	COG0697	spore germination
ISU54_RS12085	COG1794	racemase activity, acting on amino acids and derivatives
ISU54_RS12090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU54_RS12105	COG3101	peptidyl-lysine hydroxylation
ISU54_RS12110	COG0730	response to heat
ISU54_RS12125	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU54_RS12135	COG2062	phosphohistidine phosphatase, SixA
ISU54_RS12150	COG3691	Protein conserved in bacteria
ISU54_RS12165	COG3088	subunit of a heme lyase
ISU54_RS12165	COG4235	cytochrome complex assembly
ISU54_RS12170	COG4235	cytochrome complex assembly
ISU54_RS12170	COG3088	subunit of a heme lyase
ISU54_RS12175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISU54_RS12180	COG1138	Cytochrome C-type biogenesis protein
ISU54_RS12190	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU54_RS12195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU54_RS12200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU54_RS12220	COG1704	LemA family
ISU54_RS12230	COG2824	Alkylphosphonate utilization operon protein PhnA
ISU54_RS12320	COG3188	usher protein
ISU54_RS12325	COG3328	transposase activity
ISU54_RS12330	COG3188	usher protein
ISU54_RS12335	COG3121	Chaperone
ISU54_RS12395	COG2951	lytic endotransglycosylase activity
ISU54_RS12430	COG0243	molybdopterin cofactor binding
ISU54_RS12435	COG0437	4 iron, 4 sulfur cluster binding
ISU54_RS12440	COG3302	dmso reductase anchor subunit
ISU54_RS12445	COG3381	protein complex oligomerization
ISU54_RS12475	COG3038	cytochrome b561
ISU54_RS12480	COG0436	Aminotransferase
ISU54_RS12505	COG0667	Aldo Keto reductase
ISU54_RS12520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU54_RS12585	COG3530	Putative quorum-sensing-regulated virulence factor
ISU54_RS12600	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ISU54_RS12610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS12630	COG2205	protein histidine kinase activity
ISU54_RS12635	COG0745	RESPONSE REGULATOR receiver
ISU54_RS12640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU54_RS12655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISU54_RS12675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISU54_RS12685	COG5002	protein histidine kinase activity
ISU54_RS12685	COG3850	Histidine kinase
ISU54_RS12690	COG0745	RESPONSE REGULATOR receiver
ISU54_RS12705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISU54_RS12710	COG4208	sulfate ABC transporter
ISU54_RS12715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISU54_RS12720	COG4150	thiosulfate binding
ISU54_RS12730	COG1737	Transcriptional regulator
ISU54_RS12735	COG2731	YhcH YjgK YiaL family protein
ISU54_RS12745	COG4886	Leucine-rich repeat (LRR) protein
ISU54_RS12755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISU54_RS12760	COG2837	iron assimilation
ISU54_RS12770	COG3111	PFAM Bacterial OB fold (BOF) protein
ISU54_RS12810	COG3005	denitrification pathway
ISU54_RS12815	COG3043	anaerobic respiration
ISU54_RS12825	COG3062	negative regulation of establishment of protein localization
ISU54_RS12830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU54_RS12830	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU54_RS12835	COG2197	response regulator
ISU54_RS12845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU54_RS12855	COG1988	membrane-bound metal-dependent
ISU54_RS12860	COG0641	radical SAM
ISU54_RS12865	COG3119	arylsulfatase activity
ISU54_RS12875	COG3842	ATPase activity
ISU54_RS12880	COG1175	transmembrane transport
ISU54_RS12895	COG1393	Belongs to the ArsC family
ISU54_RS12905	COG1876	peptidase activity
ISU54_RS12925	COG2321	neutral zinc metallopeptidase
ISU54_RS12940	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISU54_RS12950	COG2716	regulation of RNA biosynthetic process
ISU54_RS12955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISU54_RS12965	COG0628	permease
ISU54_RS12970	COG4783	chaperone-mediated protein folding
ISU54_RS12975	COG1393	Belongs to the ArsC family
ISU54_RS13000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISU54_RS13005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU54_RS13020	COG0581	inorganic phosphate transmembrane transporter activity
ISU54_RS13030	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ISU54_RS13045	COG2239	Acts as a magnesium transporter
ISU54_RS13055	COG1177	transmembrane transport
ISU54_RS13060	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU54_RS13070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISU54_RS13080	COG3842	ATPase activity
ISU54_RS13110	COG0745	RESPONSE REGULATOR receiver
ISU54_RS13115	COG3422	double-strand break repair
ISU54_RS13120	COG0826	peptidase U32
ISU54_RS13145	COG0351	phosphomethylpyrimidine kinase
ISU54_RS13160	COG3328	transposase activity
ISU54_RS13200	COG0517	IMP dehydrogenase activity
ISU54_RS13200	COG0516	GMP reductase activity
ISU54_RS13210	COG1645	bacterial-type flagellum-dependent swarming motility
ISU54_RS13225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU54_RS13230	COG2976	Protein conserved in bacteria
ISU54_RS13270	COG3468	outer membrane autotransporter barrel domain protein
ISU54_RS13275	COG3468	outer membrane autotransporter barrel domain protein
ISU54_RS13300	COG2975	iron-sulfur cluster assembly
ISU54_RS13305	COG0633	Ferredoxin
ISU54_RS13325	COG0822	iron-sulfur transferase activity
ISU54_RS13330	COG1104	cysteine desulfurase activity
ISU54_RS13350	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU54_RS13355	COG3683	transport system, periplasmic component
ISU54_RS13360	COG3711	transcriptional antiterminator
ISU54_RS13365	COG2814	Major facilitator Superfamily
ISU54_RS13385	COG1017	nitric oxide dioxygenase activity
ISU54_RS13385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU54_RS13410	COG0347	Belongs to the P(II) protein family
ISU54_RS13415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU54_RS13415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ISU54_RS13420	COG2204	response regulator
ISU54_RS13425	COG3170	Tfp pilus assembly protein FimV
ISU54_RS13430	COG2205	protein histidine kinase activity
ISU54_RS13475	COG0560	Phosphoserine phosphatase
ISU54_RS13485	COG1737	Transcriptional regulator
ISU54_RS13490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU54_RS13505	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISU54_RS13540	COG3086	response to oxidative stress
ISU54_RS13545	COG3026	antisigma factor binding
ISU54_RS13560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISU54_RS13570	COG0513	Belongs to the DEAD box helicase family
ISU54_RS13615	COG1984	allophanate hydrolase subunit 2
ISU54_RS13630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ISU54_RS13635	COG5212	phosphodiesterase
ISU54_RS13645	COG3272	Protein of unknown function (DUF1722)
ISU54_RS13680	COG2205	protein histidine kinase activity
ISU54_RS13685	COG0745	RESPONSE REGULATOR receiver
ISU54_RS13700	COG0033	Phosphoglucomutase
ISU54_RS13705	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ISU54_RS13720	COG2169	Transcriptional regulator
ISU54_RS13720	COG1917	Cupin 2, conserved barrel domain protein
ISU54_RS13725	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISU54_RS13730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU54_RS13735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU54_RS13745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU54_RS13755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU54_RS13765	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU54_RS13770	COG4413	Urea transporter
ISU54_RS13780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISU54_RS13805	COG0831	urea catabolic process
ISU54_RS13810	COG1124	(ABC) transporter
ISU54_RS13815	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ISU54_RS13820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU54_RS13830	COG0747	negative chemotaxis
ISU54_RS13835	COG1278	Cold shock
ISU54_RS13875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISU54_RS13880	COG4175	Glycine betaine
ISU54_RS13885	COG4176	ABC-type proline glycine betaine transport system permease component
ISU54_RS13890	COG2113	Glycine betaine
ISU54_RS13925	COG0582	viral genome integration into host DNA
ISU54_RS13935	COG0596	Alpha beta hydrolase
ISU54_RS13950	COG0735	belongs to the Fur family
ISU54_RS13975	COG2190	(PTS) system
ISU54_RS13975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU54_RS13975	COG1263	PTS System
ISU54_RS13985	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISU54_RS13990	COG1940	carbohydrate kinase activity
ISU54_RS13990	COG1846	Transcriptional regulator
ISU54_RS13995	COG0647	UMP catabolic process
ISU54_RS14000	COG0367	asparagine synthase
ISU54_RS14035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU54_RS14040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ISU54_RS14045	COG1702	phosphate starvation-inducible protein PhoH
ISU54_RS14055	COG4535	Mg2 and Co2 transporter CorC
ISU54_RS14060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ISU54_RS14070	COG0765	amino acid transport
ISU54_RS14075	COG0765	amino acid transport
ISU54_RS14080	COG1126	abc transporter atp-binding protein
ISU54_RS14085	COG2888	peptidyl-tyrosine sulfation
ISU54_RS14100	COG1466	dna polymerase III delta subunit
ISU54_RS14110	COG0799	negative regulation of ribosome biogenesis
ISU54_RS14120	COG0768	penicillin binding
ISU54_RS14125	COG0772	Belongs to the SEDS family
ISU54_RS14130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU54_RS14135	COG1686	Belongs to the peptidase S11 family
ISU54_RS14155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU54_RS14160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU54_RS14170	COG1278	Cold shock
ISU54_RS14175	COG2197	response regulator
ISU54_RS14200	COG5265	(ABC) transporter
ISU54_RS14210	COG3718	enzyme involved in inositol metabolism
ISU54_RS14220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU54_RS14225	COG0673	inositol 2-dehydrogenase activity
ISU54_RS14230	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS14235	COG1129	ABC transporter
ISU54_RS14250	COG3962	Belongs to the TPP enzyme family
ISU54_RS14270	COG2373	Large extracellular alpha-helical protein
ISU54_RS14280	COG4953	penicillin-binding protein 1C
ISU54_RS14285	COG3423	Transcriptional regulator
ISU54_RS14340	COG3328	transposase activity
ISU54_RS14355	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU54_RS14365	COG0656	L-ascorbic acid biosynthetic process
ISU54_RS14370	COG0667	Aldo Keto reductase
ISU54_RS14400	COG0671	phosphoesterase, PA-phosphatase related
ISU54_RS14400	COG2453	phosphatase
ISU54_RS14405	COG2267	carboxylic ester hydrolase activity
ISU54_RS14415	COG4589	Belongs to the CDS family
ISU54_RS14420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISU54_RS14430	COG0582	viral genome integration into host DNA
ISU54_RS14465	COG2501	S4 domain
ISU54_RS14480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU54_RS14490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISU54_RS14495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISU54_RS14500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISU54_RS14505	COG4181	ATPase activity
ISU54_RS14510	COG2755	lipolytic protein G-D-S-L family
ISU54_RS14515	COG0300	oxidoreductase activity
ISU54_RS14520	COG3118	belongs to the thioredoxin family
ISU54_RS14525	COG0330	HflC and HflK could
ISU54_RS14530	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISU54_RS14535	COG0789	Transcriptional regulator
ISU54_RS14540	COG2217	Heavy metal translocating P-type atpase
ISU54_RS14545	COG3735	TraB family
ISU54_RS14550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISU54_RS14565	COG2223	nitrite transmembrane transporter activity
ISU54_RS14570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU54_RS14570	COG4651	solute:proton antiporter activity
ISU54_RS14575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU54_RS14580	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU54_RS14600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU54_RS14640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU54_RS14660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU54_RS14660	COG0543	2 iron, 2 sulfur cluster binding
ISU54_RS14690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ISU54_RS14700	COG2832	Protein of unknown function (DUF454)
ISU54_RS14715	COG3264	Mechanosensitive ion channel
ISU54_RS14715	COG1196	nuclear chromosome segregation
ISU54_RS14720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISU54_RS14725	COG1309	transcriptional regulator
ISU54_RS14730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU54_RS14735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU54_RS14745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU54_RS14770	COG3695	enzyme binding
ISU54_RS14775	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISU54_RS14780	COG1946	Acyl-CoA thioesterase
ISU54_RS14785	COG0004	ammonium transporteR
ISU54_RS14790	COG0347	Belongs to the P(II) protein family
ISU54_RS14795	COG1132	(ABC) transporter
ISU54_RS14800	COG1132	(ABC) transporter
ISU54_RS14805	COG1522	sequence-specific DNA binding
ISU54_RS14820	COG4533	DNA binding
ISU54_RS14830	COG0824	Thioesterase
ISU54_RS14835	COG1555	photosystem II stabilization
ISU54_RS14840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU54_RS14845	COG0776	regulation of translation
ISU54_RS14850	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISU54_RS14870	COG0271	Belongs to the BolA IbaG family
ISU54_RS14875	COG3056	Lipoprotein
ISU54_RS14880	COG2223	nitrite transmembrane transporter activity
ISU54_RS14890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISU54_RS14895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISU54_RS14900	COG1845	cytochrome c oxidase, subunit III
ISU54_RS14905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISU54_RS14915	COG2814	Major facilitator Superfamily
ISU54_RS14925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISU54_RS14930	COG0693	protein deglycase activity
ISU54_RS14945	COG0142	geranyltranstransferase activity
ISU54_RS14970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISU54_RS14975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISU54_RS14990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU54_RS14990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU54_RS15015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU54_RS15020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU54_RS15025	COG1862	Preprotein translocase
ISU54_RS15045	COG0450	alkyl hydroperoxide reductase
ISU54_RS15065	COG0366	Alpha amylase catalytic
ISU54_RS15085	COG5002	protein histidine kinase activity
ISU54_RS15090	COG0745	RESPONSE REGULATOR receiver
ISU54_RS15095	COG0420	3'-5' exonuclease activity
ISU54_RS15100	COG0419	ATPase involved in DNA repair
ISU54_RS15105	COG1940	carbohydrate kinase activity
ISU54_RS15130	COG2226	methyltransferase
ISU54_RS15180	COG0583	DNA-binding transcription factor activity
ISU54_RS15185	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU54_RS15205	COG1477	protein flavinylation
ISU54_RS15225	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU54_RS15230	COG1805	sodium ion transport
ISU54_RS15240	COG3034	peptidoglycan biosynthetic process
ISU54_RS15245	COG0121	glutamine amidotransferase
ISU54_RS15255	COG1960	acyl-CoA dehydrogenase activity
ISU54_RS15265	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ISU54_RS15290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU54_RS15305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU54_RS15315	COG0765	amino acid transport
ISU54_RS15350	COG2814	Major facilitator Superfamily
ISU54_RS15355	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISU54_RS15365	COG1846	Transcriptional regulator
ISU54_RS15370	COG1566	PFAM secretion protein HlyD family protein
ISU54_RS15375	COG2814	Major facilitator Superfamily
ISU54_RS15380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU54_RS15385	COG3118	belongs to the thioredoxin family
ISU54_RS15390	COG3148	PFAM DTW domain containing protein
ISU54_RS15395	COG0045	succinate-CoA ligase (ADP-forming) activity
ISU54_RS15395	COG1042	CoA-binding domain protein
ISU54_RS15395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU54_RS15400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISU54_RS15405	COG5544	Lipoprotein
ISU54_RS15435	COG0542	response to heat
ISU54_RS15445	COG0564	pseudouridine synthase activity
ISU54_RS15450	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU54_RS15455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISU54_RS15485	COG0287	Prephenate dehydrogenase
ISU54_RS15485	COG1605	Chorismate mutase
ISU54_RS15490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU54_RS15495	COG3279	Response regulator of the LytR AlgR family
ISU54_RS15505	COG3137	Salt-induced outer membrane protein
ISU54_RS15535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISU54_RS15540	COG4137	Cytochrome C assembly protein
ISU54_RS15545	COG4536	flavin adenine dinucleotide binding
ISU54_RS15560	COG2918	glutathione biosynthetic process
ISU54_RS15565	COG1238	metal cluster binding
ISU54_RS15570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU54_RS15600	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISU54_RS15640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU54_RS15645	COG3958	Transketolase
ISU54_RS15650	COG3959	Transketolase, thiamine diphosphate binding domain
ISU54_RS15655	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS15660	COG1129	ABC transporter
ISU54_RS15670	COG1879	ABC-type sugar transport system periplasmic component
ISU54_RS15680	COG3783	Cytochrome b(562)
ISU54_RS15685	COG3038	cytochrome b561
ISU54_RS15690	COG3381	protein complex oligomerization
ISU54_RS15695	COG3302	dmso reductase anchor subunit
ISU54_RS15700	COG0437	4 iron, 4 sulfur cluster binding
ISU54_RS15705	COG0243	molybdopterin cofactor binding
ISU54_RS15710	COG0235	Class ii aldolase
ISU54_RS15715	COG1349	DNA-binding transcription factor activity
ISU54_RS15730	COG1129	ABC transporter
ISU54_RS15735	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS15740	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS15745	COG3623	hexulose-6-phosphate isomerase
ISU54_RS15750	COG1070	Carbohydrate kinase
ISU54_RS15755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU54_RS15755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU54_RS15765	COG0024	Methionine aminopeptidase
ISU54_RS15775	COG4771	TonB-dependent receptor
ISU54_RS15785	COG1858	cytochrome C peroxidase
ISU54_RS15790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS15810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISU54_RS15825	COG2376	Dihydroxyacetone kinase
ISU54_RS15830	COG1028	Short-chain dehydrogenase reductase Sdr
ISU54_RS15835	COG1063	alcohol dehydrogenase
ISU54_RS15840	COG0698	ribose 5-phosphate isomerase
ISU54_RS15850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISU54_RS15855	COG4942	peptidase
ISU54_RS15855	COG1388	LysM domain
ISU54_RS15895	COG0529	Catalyzes the synthesis of activated sulfate
ISU54_RS15950	COG0720	synthase
ISU54_RS15955	COG0602	queuosine metabolic process
ISU54_RS15975	COG3956	TIGRFAM MazG family protein
ISU54_RS15980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU54_RS15985	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ISU54_RS15995	COG2205	protein histidine kinase activity
ISU54_RS15995	COG4999	Histidine kinase
ISU54_RS15995	COG3850	Histidine kinase
ISU54_RS15995	COG3437	response regulator, receiver
ISU54_RS16000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU54_RS16020	COG2860	membrane
ISU54_RS16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS16045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU54_RS16050	COG1120	ATPase activity
ISU54_RS16055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISU54_RS16060	COG1643	Atp-dependent helicase
ISU54_RS16065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISU54_RS16080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ISU54_RS16085	COG0617	tRNA 3'-terminal CCA addition
ISU54_RS16090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISU54_RS16115	COG0842	Transport permease protein
ISU54_RS16120	COG1131	(ABC) transporter
ISU54_RS16125	COG0288	reversible hydration of carbon dioxide
ISU54_RS16130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ISU54_RS16135	COG2132	Multicopper oxidase
ISU54_RS16155	COG0697	spore germination
ISU54_RS16165	COG1049	propionate catabolic process, 2-methylcitrate cycle
ISU54_RS16175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU54_RS16180	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU54_RS16185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISU54_RS16190	COG2186	Transcriptional regulator
ISU54_RS16195	COG1113	amino acid transport
ISU54_RS16200	COG3725	Membrane protein required for beta-lactamase induction
ISU54_RS16205	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU54_RS16215	COG4969	Belongs to the N-Me-Phe pilin family
ISU54_RS16220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU54_RS16225	COG1459	type II secretion system
ISU54_RS16275	COG0582	viral genome integration into host DNA
ISU54_RS16285	COG0795	lipopolysaccharide-transporting ATPase activity
ISU54_RS16290	COG0795	lipopolysaccharide-transporting ATPase activity
ISU54_RS16300	COG2927	DNA polymerase III (CHI subunit)
ISU54_RS16305	COG0525	valine-tRNA ligase activity
ISU54_RS16315	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ISU54_RS16325	COG2731	YhcH YjgK YiaL family protein
ISU54_RS16335	COG0601	transmembrane transport
ISU54_RS16340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU54_RS16345	COG0444	Belongs to the ABC transporter superfamily
ISU54_RS16350	COG4608	Belongs to the ABC transporter superfamily
ISU54_RS16365	COG2188	Transcriptional regulator
ISU54_RS16370	COG3624	Phosphonate C-P lyase system protein PhnG
ISU54_RS16375	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISU54_RS16380	COG3626	phosphonate metabolism
ISU54_RS16385	COG3627	carbon phosphorus lyase activity
ISU54_RS16390	COG4107	phosphonate C-P lyase system protein PhnK
ISU54_RS16395	COG4778	phosphonate C-P lyase system protein PhnL
ISU54_RS16400	COG3454	Phosphonate metabolism
ISU54_RS16405	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ISU54_RS16410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ISU54_RS16415	COG0702	epimerase
ISU54_RS16430	COG3842	ATPase activity
ISU54_RS16435	COG0395	ABC-type sugar transport system, permease component
ISU54_RS16440	COG1175	transmembrane transport
ISU54_RS16445	COG1653	transport
ISU54_RS16465	COG3153	acetyltransferase
ISU54_RS16470	COG3154	lipid carrier protein
ISU54_RS16475	COG0826	peptidase U32
ISU54_RS16480	COG0826	peptidase U32
ISU54_RS16490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU54_RS16500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISU54_RS16520	COG0513	Belongs to the DEAD box helicase family
ISU54_RS16565	COG0195	Participates in both transcription termination and antitermination
ISU54_RS16585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISU54_RS16595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISU54_RS16610	COG1534	Rna-binding protein
ISU54_RS16620	COG2027	D-alanyl-D-alanine carboxypeptidase
ISU54_RS16625	COG0745	RESPONSE REGULATOR receiver
ISU54_RS16630	COG0642	Histidine kinase
ISU54_RS16640	COG0697	spore germination
ISU54_RS16655	COG0142	geranyltranstransferase activity
ISU54_RS16665	COG3423	Transcriptional regulator
ISU54_RS16685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISU54_RS16690	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ISU54_RS16695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ISU54_RS16700	COG2105	PFAM AIG2 family protein
ISU54_RS16705	COG2911	Protein conserved in bacteria
ISU54_RS16710	COG0729	surface antigen
ISU54_RS16720	COG1253	flavin adenine dinucleotide binding
ISU54_RS16730	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISU54_RS16740	COG0737	Belongs to the 5'-nucleotidase family
ISU54_RS16750	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU54_RS16755	COG3061	Opacity-associated protein A
ISU54_RS16775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISU54_RS16785	COG0360	Binds together with S18 to 16S ribosomal RNA
ISU54_RS16790	COG1073	alpha beta
ISU54_RS16810	COG3650	response to hydrogen peroxide
ISU54_RS16815	COG1960	acyl-CoA dehydrogenase activity
ISU54_RS16820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU54_RS16825	COG0557	exoribonuclease II activity
ISU54_RS16840	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISU54_RS16845	COG0330	HflC and HflK could
ISU54_RS16850	COG0330	HflC and HflK could
ISU54_RS16855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISU54_RS16875	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU54_RS16880	COG0802	atpase or kinase
ISU54_RS16885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISU54_RS16885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISU54_RS16890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISU54_RS16905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ISU54_RS16920	COG3264	Mechanosensitive ion channel
ISU54_RS16920	COG1511	domain protein
ISU54_RS16935	COG1053	succinate dehydrogenase
ISU54_RS16940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISU54_RS16950	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ISU54_RS16995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISU54_RS17010	COG3383	formate dehydrogenase (NAD+) activity
ISU54_RS17015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU54_RS17020	COG0493	'glutamate synthase
ISU54_RS17020	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU54_RS17025	COG1309	transcriptional regulator
ISU54_RS17085	COG1454	alcohol dehydrogenase
ISU54_RS17095	COG0629	single-stranded DNA binding
ISU54_RS17100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ISU54_RS17105	COG2315	Protein conserved in bacteria
ISU54_RS17110	COG1448	Aminotransferase
ISU54_RS17135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU54_RS17140	COG0735	belongs to the Fur family
ISU54_RS17150	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISU54_RS17190	COG3121	Chaperone
ISU54_RS17250	COG1358	cellular component organization or biogenesis
ISU54_RS17275	COG3721	Heme iron utilization protein
ISU54_RS17280	COG0702	epimerase
ISU54_RS17290	COG4771	TonB-dependent receptor
ISU54_RS17295	COG3720	iron ion transport
ISU54_RS17300	COG4558	Periplasmic binding protein
ISU54_RS17305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU54_RS17315	COG0626	cystathionine gamma-synthase activity
ISU54_RS17320	COG0814	amino acid
ISU54_RS17325	COG0583	DNA-binding transcription factor activity
ISU54_RS17330	COG0425	Belongs to the sulfur carrier protein TusA family
ISU54_RS17335	COG2391	methyltransferase activity
ISU54_RS17445	COG1301	dicarboxylic acid transport
ISU54_RS17455	COG3162	membrane
ISU54_RS17515	COG0151	Belongs to the GarS family
ISU54_RS17535	COG1515	deoxyribonuclease V activity
ISU54_RS17570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISU54_RS17625	COG0250	Participates in transcription elongation, termination and antitermination
ISU54_RS17685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISU54_RS17715	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISU54_RS17720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ISU54_RS17735	COG1739	Uncharacterized protein family UPF0029
ISU54_RS17760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISU54_RS17795	COG0805	protein transport
ISU54_RS17805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU54_RS17825	COG1322	Protein conserved in bacteria
ISU54_RS17830	COG0586	Pfam SNARE associated Golgi protein
ISU54_RS17835	COG1966	Carbon starvation protein
ISU54_RS17850	COG0412	Dienelactone hydrolase
ISU54_RS17860	COG0583	DNA-binding transcription factor activity
ISU54_RS17865	COG0697	spore germination
ISU54_RS17870	COG0679	Auxin Efflux Carrier
ISU54_RS17875	COG0584	glycerophosphoryl diester phosphodiesterase
ISU54_RS17935	COG0410	ABC transporter
ISU54_RS17945	COG4177	L-phenylalanine transmembrane transporter activity
ISU54_RS17955	COG0683	leucine binding
ISU54_RS17975	COG2177	Part of the ABC transporter FtsEX involved in
ISU54_RS17980	COG2884	Cell division ATP-binding protein ftsE
ISU54_RS17985	COG0552	protein localization to endoplasmic reticulum
ISU54_RS17985	COG0552	protein localization to endoplasmic reticulum
ISU54_RS17990	COG0742	ribosomal rna small subunit methyltransferase
ISU54_RS17995	COG3776	membrane
ISU54_RS18010	COG3714	YhhN family
ISU54_RS18025	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISU54_RS18035	COG0247	lactate metabolic process
ISU54_RS18045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU54_RS18050	COG0584	glycerophosphoryl diester phosphodiesterase
ISU54_RS18060	COG0561	phosphatase activity
ISU54_RS18065	COG2267	carboxylic ester hydrolase activity
ISU54_RS18070	COG1280	lysine exporter protein (LysE YggA)
ISU54_RS18075	COG1280	lysine exporter protein (LysE YggA)
ISU54_RS18080	COG0514	ATP-dependent DNA helicase (RecQ)
ISU54_RS18085	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ISU54_RS18090	COG2050	protein possibly involved in aromatic compounds catabolism
ISU54_RS18105	COG5564	TIM-barrel signal transduction protein
ISU54_RS18110	COG5441	Belongs to the UPF0261 family
ISU54_RS18120	COG0210	DNA helicase
ISU54_RS18125	COG1011	Hydrolase
ISU54_RS18130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ISU54_RS18135	COG3159	Protein conserved in bacteria
ISU54_RS18155	COG3072	Adenylate cyclase
ISU54_RS18170	COG1587	Uroporphyrinogen-III synthase
ISU54_RS18175	COG2959	enzyme of heme biosynthesis
ISU54_RS18180	COG3071	HemY protein
ISU54_RS18210	COG1113	amino acid transport
ISU54_RS18230	COG2244	polysaccharide biosynthetic process
ISU54_RS18235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISU54_RS18240	COG0456	acetyltransferase
ISU54_RS18245	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISU54_RS18250	COG1088	dTDP-glucose 4,6-dehydratase activity
ISU54_RS18255	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISU54_RS18260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISU54_RS18265	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU54_RS18270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISU54_RS18275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISU54_RS18280	COG3118	belongs to the thioredoxin family
ISU54_RS18305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU54_RS18315	COG3328	transposase activity
ISU54_RS18325	COG3121	Chaperone
ISU54_RS18340	COG3121	Chaperone
ISU54_RS18375	COG0583	DNA-binding transcription factor activity
ISU54_RS18420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU54_RS18425	COG3978	acetolactate synthase activity
ISU54_RS18445	COG3085	chromosome segregation
ISU54_RS18455	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS18460	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS18465	COG1129	ABC transporter
ISU54_RS18470	COG1879	ABC-type sugar transport system periplasmic component
ISU54_RS18540	COG0678	peroxiredoxin activity
ISU54_RS18540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU54_RS18545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU54_RS18570	COG1629	transport
ISU54_RS18585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISU54_RS18610	COG0527	aspartate kinase activity
ISU54_RS18610	COG0460	homoserine dehydrogenase
ISU54_RS18625	COG4682	membrane
ISU54_RS18635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISU54_RS18640	COG1609	Transcriptional regulator
ISU54_RS18645	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU54_RS18660	COG1575	Belongs to the MenA family. Type 1 subfamily
ISU54_RS18770	COG3501	Rhs element vgr protein
ISU54_RS18815	COG3501	Rhs element vgr protein
ISU54_RS18825	COG3209	COG3209 Rhs family protein
ISU54_RS18845	COG0673	inositol 2-dehydrogenase activity
ISU54_RS18850	COG1917	Cupin 2, conserved barrel domain protein
ISU54_RS18850	COG2207	Transcriptional regulator
ISU54_RS18855	COG1869	D-ribose catabolic process
ISU54_RS18860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU54_RS18865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ISU54_RS18870	COG0431	NADPH-dependent FMN reductase
ISU54_RS18875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISU54_RS18885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU54_RS18900	COG3077	Addiction module antitoxin, RelB DinJ family
ISU54_RS18905	COG2252	PERMEase
ISU54_RS18910	COG0025	NhaP-type Na H and K H
ISU54_RS18920	COG1560	Kdo2-lipid A biosynthetic process
ISU54_RS18930	COG1129	ABC transporter
ISU54_RS18935	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU54_RS18945	COG1069	ribulokinase activity
ISU54_RS18955	COG0625	glutathione transferase activity
ISU54_RS18975	COG1278	Cold shock
ISU54_RS18980	COG1278	Cold shock
ISU54_RS18985	COG3133	Outer membrane lipoprotein
ISU54_RS18990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU54_RS19000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU54_RS19030	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ISU54_RS19035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU54_RS19045	COG4145	pantothenate transmembrane transporter activity
ISU54_RS19050	COG3924	membrane
ISU54_RS19060	COG0439	Biotin carboxylase
ISU54_RS19065	COG0511	ligase activity, forming carbon-carbon bonds
ISU54_RS19080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ISU54_RS19085	COG0604	alcohol dehydrogenase
ISU54_RS19090	COG2199	diguanylate cyclase activity
ISU54_RS19090	COG2200	EAL domain
ISU54_RS19095	COG1077	Cell shape determining protein MreB Mrl
ISU54_RS19100	COG1792	Involved in formation and maintenance of cell shape
ISU54_RS19105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISU54_RS19110	COG0424	maF-like protein
ISU54_RS19115	COG1530	ribonuclease E activity
ISU54_RS19120	COG3164	Protein of unknown function
ISU54_RS19125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU54_RS19130	COG0312	modulator of DNA gyrase
ISU54_RS19180	COG0583	DNA-binding transcription factor activity
ISU54_RS19210	COG2732	(Barnase) inhibitor
ISU54_RS19220	COG0312	modulator of DNA gyrase
ISU54_RS19230	COG3783	Cytochrome b(562)
ISU54_RS19235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU54_RS19240	COG0366	Alpha amylase catalytic
ISU54_RS19245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU54_RS19245	COG1263	PTS System
ISU54_RS19250	COG1609	Transcriptional regulator
ISU54_RS19275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS19295	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISU54_RS19300	COG1137	ATPase activity
ISU54_RS19305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISU54_RS19310	COG3117	lipopolysaccharide transmembrane transporter activity
ISU54_RS19315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISU54_RS19320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISU54_RS19320	COG0517	IMP dehydrogenase activity
ISU54_RS19325	COG0530	calcium, potassium:sodium antiporter activity
ISU54_RS19330	COG1127	ABC transporter
ISU54_RS19335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISU54_RS19340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU54_RS19345	COG2854	intermembrane phospholipid transfer
ISU54_RS19350	COG3113	response to antibiotic
ISU54_RS19355	COG5007	Belongs to the BolA IbaG family
ISU54_RS19365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU54_RS19375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU54_RS19380	COG3105	Protein conserved in bacteria
ISU54_RS19385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISU54_RS19405	COG0625	glutathione transferase activity
ISU54_RS19410	COG2969	positive regulation of protein catabolic process
ISU54_RS19420	COG0493	'glutamate synthase
ISU54_RS19425	COG0070	glutamate synthase
ISU54_RS19425	COG0067	glutamate synthase
ISU54_RS19425	COG0069	glutamate synthase activity
ISU54_RS19430	COG1242	4 iron, 4 sulfur cluster binding
ISU54_RS19435	COG5002	protein histidine kinase activity
ISU54_RS19435	COG0784	Response regulator, receiver
ISU54_RS19435	COG2198	Histidine kinase
ISU54_RS19440	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISU54_RS19450	COG2823	Periplasmic or secreted lipoprotein
ISU54_RS19470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISU54_RS19480	COG1741	Belongs to the pirin family
ISU54_RS19485	COG0583	DNA-binding transcription factor activity
ISU54_RS19505	COG0456	acetyltransferase
ISU54_RS19510	COG2982	Protein involved in outer membrane biogenesis
ISU54_RS19515	COG2233	PERMEase
ISU54_RS19520	COG0786	glutamate:sodium symporter activity
ISU54_RS19530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISU54_RS19535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU54_RS19540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU54_RS19560	COG2860	membrane
ISU54_RS19565	COG1561	YicC-like family, N-terminal region
ISU54_RS19590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISU54_RS19625	COG1519	Transferase
ISU54_RS19630	COG0859	PFAM glycosyl transferase family 9
ISU54_RS19635	COG0859	PFAM glycosyl transferase family 9
ISU54_RS19645	COG0156	8-amino-7-oxononanoate synthase activity
ISU54_RS19660	COG4942	peptidase
ISU54_RS19670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISU54_RS19675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU54_RS19690	COG1045	serine acetyltransferase
ISU54_RS19695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISU54_RS19700	COG2169	Transcriptional regulator
ISU54_RS19700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU54_RS19705	COG2205	protein histidine kinase activity
ISU54_RS19710	COG0745	RESPONSE REGULATOR receiver
ISU54_RS19715	COG3678	ATP-independent chaperone mediated protein folding
ISU54_RS19740	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISU54_RS19750	COG0471	metal ion transport
ISU54_RS19755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISU54_RS19760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISU54_RS19765	COG0583	DNA-binding transcription factor activity
ISU54_RS19780	COG3152	Membrane
ISU54_RS19790	COG1494	fructose-1,6-bisphosphatase
ISU54_RS19795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU54_RS19800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ISU54_RS19845	COG0560	Phosphoserine phosphatase
ISU54_RS19850	COG3726	membrane protein affecting hemolysin expression
ISU54_RS19875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU54_RS19880	COG0084	hydrolase, TatD family'
ISU54_RS19885	COG4667	esterase of the alpha-beta hydrolase superfamily
ISU54_RS19895	COG2823	Periplasmic or secreted lipoprotein
ISU54_RS19905	COG0456	acetyltransferase
ISU54_RS19910	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISU54_RS19950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU54_RS19955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU54_RS19970	COG0859	PFAM glycosyl transferase family 9
ISU54_RS19975	COG1070	Carbohydrate kinase
ISU54_RS20025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS20025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU54_RS20025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU54_RS20030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU54_RS20035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU54_RS20040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU54_RS20045	COG2207	Transcriptional regulator
ISU54_RS20055	COG4269	membrane
ISU54_RS20110	COG1401	restriction endodeoxyribonuclease activity
ISU54_RS20135	COG1011	Hydrolase
ISU54_RS20145	COG0174	glutamine synthetase
ISU54_RS20150	COG3852	Histidine kinase
ISU54_RS20160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU54_RS20185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU54_RS20185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU54_RS20190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU54_RS20195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISU54_RS20200	COG3084	Protein conserved in bacteria
ISU54_RS20210	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISU54_RS20215	COG3328	transposase activity
ISU54_RS20240	COG2186	Transcriptional regulator
ISU54_RS20245	COG0477	Major facilitator Superfamily
ISU54_RS20260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU54_RS20290	COG1522	sequence-specific DNA binding
ISU54_RS20295	COG0716	FMN binding
ISU54_RS20310	COG3312	ion transport
ISU54_RS20365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISU54_RS20370	COG0573	inorganic phosphate transmembrane transporter activity
ISU54_RS20375	COG0581	inorganic phosphate transmembrane transporter activity
ISU54_RS20385	COG0704	Plays a role in the regulation of phosphate uptake
ISU54_RS20395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU54_RS20400	COG0765	amino acid transport
ISU54_RS20405	COG0765	amino acid transport
ISU54_RS20410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU54_RS20420	COG2252	PERMEase
ISU54_RS20450	COG0706	membrane insertase activity
ISU54_RS20465	COG0230	Belongs to the bacterial ribosomal protein bL34 family