locus-tag	class	description
ISU55_RS00010	COG0592	DNA-directed DNA polymerase activity
ISU55_RS00020	COG0187	DNA topoisomerase II activity
ISU55_RS00025	COG0561	phosphatase activity
ISU55_RS00035	COG2423	ornithine cyclodeaminase activity
ISU55_RS00040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ISU55_RS00050	COG5645	(Lipo)protein
ISU55_RS00070	COG3977	Valine--pyruvate aminotransferase
ISU55_RS00080	COG0366	Alpha amylase catalytic
ISU55_RS00095	COG2885	chlorophyll binding
ISU55_RS00105	COG2818	Glycosylase
ISU55_RS00130	COG2213	PTS system mannitol-specific
ISU55_RS00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS00140	COG3722	fumarate hydratase activity
ISU55_RS00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ISU55_RS00180	COG0437	4 iron, 4 sulfur cluster binding
ISU55_RS00185	COG2864	formate dehydrogenase
ISU55_RS00200	COG3276	selenocysteine insertion sequence binding
ISU55_RS00305	COG3501	Rhs element vgr protein
ISU55_RS00350	COG3501	Rhs element vgr protein
ISU55_RS00360	COG3209	COG3209 Rhs family protein
ISU55_RS00380	COG0673	inositol 2-dehydrogenase activity
ISU55_RS00385	COG2207	Transcriptional regulator
ISU55_RS00385	COG1917	Cupin 2, conserved barrel domain protein
ISU55_RS00390	COG1869	D-ribose catabolic process
ISU55_RS00395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU55_RS00400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ISU55_RS00405	COG0431	NADPH-dependent FMN reductase
ISU55_RS00410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ISU55_RS00420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU55_RS00435	COG3077	Addiction module antitoxin, RelB DinJ family
ISU55_RS00440	COG2252	PERMEase
ISU55_RS00445	COG0025	NhaP-type Na H and K H
ISU55_RS00455	COG1560	Kdo2-lipid A biosynthetic process
ISU55_RS00465	COG1129	ABC transporter
ISU55_RS00470	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS00480	COG1069	ribulokinase activity
ISU55_RS00490	COG0625	glutathione transferase activity
ISU55_RS00510	COG1278	Cold shock
ISU55_RS00515	COG1278	Cold shock
ISU55_RS00520	COG3133	Outer membrane lipoprotein
ISU55_RS00525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU55_RS00535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU55_RS00565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ISU55_RS00570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU55_RS00580	COG4145	pantothenate transmembrane transporter activity
ISU55_RS00585	COG3924	membrane
ISU55_RS00595	COG0439	Biotin carboxylase
ISU55_RS00600	COG0511	ligase activity, forming carbon-carbon bonds
ISU55_RS00615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ISU55_RS00620	COG0604	alcohol dehydrogenase
ISU55_RS00625	COG2200	EAL domain
ISU55_RS00625	COG2199	diguanylate cyclase activity
ISU55_RS00630	COG1077	Cell shape determining protein MreB Mrl
ISU55_RS00635	COG1792	Involved in formation and maintenance of cell shape
ISU55_RS00640	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ISU55_RS00645	COG0424	maF-like protein
ISU55_RS00650	COG1530	ribonuclease E activity
ISU55_RS00655	COG3164	Protein of unknown function
ISU55_RS00660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU55_RS00665	COG0312	modulator of DNA gyrase
ISU55_RS00725	COG0583	DNA-binding transcription factor activity
ISU55_RS00755	COG2732	(Barnase) inhibitor
ISU55_RS00765	COG0312	modulator of DNA gyrase
ISU55_RS00775	COG3783	Cytochrome b(562)
ISU55_RS00780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU55_RS00785	COG0366	Alpha amylase catalytic
ISU55_RS00790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU55_RS00790	COG1263	PTS System
ISU55_RS00795	COG1609	Transcriptional regulator
ISU55_RS00820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS00840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ISU55_RS00845	COG1137	ATPase activity
ISU55_RS00850	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ISU55_RS00855	COG3117	lipopolysaccharide transmembrane transporter activity
ISU55_RS00860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ISU55_RS00865	COG0517	IMP dehydrogenase activity
ISU55_RS00865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ISU55_RS00870	COG0530	calcium, potassium:sodium antiporter activity
ISU55_RS00875	COG1127	ABC transporter
ISU55_RS00880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ISU55_RS00885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU55_RS00890	COG2854	intermembrane phospholipid transfer
ISU55_RS00895	COG3113	response to antibiotic
ISU55_RS00900	COG5007	Belongs to the BolA IbaG family
ISU55_RS00910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU55_RS00920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU55_RS00925	COG3105	Protein conserved in bacteria
ISU55_RS00930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ISU55_RS00950	COG0625	glutathione transferase activity
ISU55_RS00955	COG2969	positive regulation of protein catabolic process
ISU55_RS00965	COG0493	'glutamate synthase
ISU55_RS00970	COG0070	glutamate synthase
ISU55_RS00970	COG0067	glutamate synthase
ISU55_RS00970	COG0069	glutamate synthase activity
ISU55_RS00975	COG1242	4 iron, 4 sulfur cluster binding
ISU55_RS00980	COG2198	Histidine kinase
ISU55_RS00980	COG0784	Response regulator, receiver
ISU55_RS00980	COG5002	protein histidine kinase activity
ISU55_RS00985	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ISU55_RS00995	COG2823	Periplasmic or secreted lipoprotein
ISU55_RS01015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ISU55_RS01025	COG1741	Belongs to the pirin family
ISU55_RS01030	COG0583	DNA-binding transcription factor activity
ISU55_RS01080	COG1879	ABC-type sugar transport system periplasmic component
ISU55_RS01085	COG1129	ABC transporter
ISU55_RS01090	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS01095	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS01105	COG3085	chromosome segregation
ISU55_RS01125	COG3978	acetolactate synthase activity
ISU55_RS01130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU55_RS01175	COG0583	DNA-binding transcription factor activity
ISU55_RS01210	COG3121	Chaperone
ISU55_RS01225	COG3121	Chaperone
ISU55_RS01235	COG3328	transposase activity
ISU55_RS01245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU55_RS01270	COG3118	belongs to the thioredoxin family
ISU55_RS01275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ISU55_RS01280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ISU55_RS01285	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU55_RS01290	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ISU55_RS01295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ISU55_RS01300	COG1088	dTDP-glucose 4,6-dehydratase activity
ISU55_RS01305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ISU55_RS01310	COG0456	acetyltransferase
ISU55_RS01315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ISU55_RS01320	COG2244	polysaccharide biosynthetic process
ISU55_RS01340	COG1113	amino acid transport
ISU55_RS01370	COG3071	HemY protein
ISU55_RS01375	COG2959	enzyme of heme biosynthesis
ISU55_RS01380	COG1587	Uroporphyrinogen-III synthase
ISU55_RS01395	COG3072	Adenylate cyclase
ISU55_RS01415	COG3159	Protein conserved in bacteria
ISU55_RS01420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ISU55_RS01425	COG1011	Hydrolase
ISU55_RS01430	COG0210	DNA helicase
ISU55_RS01440	COG5441	Belongs to the UPF0261 family
ISU55_RS01445	COG5564	TIM-barrel signal transduction protein
ISU55_RS01460	COG2050	protein possibly involved in aromatic compounds catabolism
ISU55_RS01465	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ISU55_RS01470	COG0514	ATP-dependent DNA helicase (RecQ)
ISU55_RS01475	COG1280	lysine exporter protein (LysE YggA)
ISU55_RS01480	COG1280	lysine exporter protein (LysE YggA)
ISU55_RS01485	COG2267	carboxylic ester hydrolase activity
ISU55_RS01490	COG0561	phosphatase activity
ISU55_RS01500	COG0584	glycerophosphoryl diester phosphodiesterase
ISU55_RS01505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU55_RS01515	COG0247	lactate metabolic process
ISU55_RS01525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ISU55_RS01540	COG3714	YhhN family
ISU55_RS01555	COG3776	membrane
ISU55_RS01560	COG0742	ribosomal rna small subunit methyltransferase
ISU55_RS01565	COG0552	protein localization to endoplasmic reticulum
ISU55_RS01565	COG0552	protein localization to endoplasmic reticulum
ISU55_RS01570	COG2884	Cell division ATP-binding protein ftsE
ISU55_RS01575	COG2177	Part of the ABC transporter FtsEX involved in
ISU55_RS01595	COG0683	leucine binding
ISU55_RS01605	COG4177	L-phenylalanine transmembrane transporter activity
ISU55_RS01615	COG0410	ABC transporter
ISU55_RS01675	COG0584	glycerophosphoryl diester phosphodiesterase
ISU55_RS01680	COG0679	Auxin Efflux Carrier
ISU55_RS01685	COG0697	spore germination
ISU55_RS01690	COG0583	DNA-binding transcription factor activity
ISU55_RS01700	COG0412	Dienelactone hydrolase
ISU55_RS01715	COG1966	Carbon starvation protein
ISU55_RS01720	COG0586	Pfam SNARE associated Golgi protein
ISU55_RS01725	COG1322	Protein conserved in bacteria
ISU55_RS01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU55_RS01755	COG0805	protein transport
ISU55_RS01790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ISU55_RS01830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ISU55_RS01835	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ISU55_RS01865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ISU55_RS01925	COG0250	Participates in transcription elongation, termination and antitermination
ISU55_RS01980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ISU55_RS02015	COG1515	deoxyribonuclease V activity
ISU55_RS02035	COG0151	Belongs to the GarS family
ISU55_RS02095	COG3162	membrane
ISU55_RS02105	COG1301	dicarboxylic acid transport
ISU55_RS02215	COG2391	methyltransferase activity
ISU55_RS02220	COG0425	Belongs to the sulfur carrier protein TusA family
ISU55_RS02225	COG0583	DNA-binding transcription factor activity
ISU55_RS02230	COG0814	amino acid
ISU55_RS02235	COG0626	cystathionine gamma-synthase activity
ISU55_RS02245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS02250	COG4558	Periplasmic binding protein
ISU55_RS02255	COG3720	iron ion transport
ISU55_RS02260	COG4771	TonB-dependent receptor
ISU55_RS02270	COG0702	epimerase
ISU55_RS02275	COG3721	Heme iron utilization protein
ISU55_RS02300	COG1358	cellular component organization or biogenesis
ISU55_RS02360	COG3121	Chaperone
ISU55_RS02400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ISU55_RS02410	COG0735	belongs to the Fur family
ISU55_RS02415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU55_RS02440	COG1448	Aminotransferase
ISU55_RS02445	COG2315	Protein conserved in bacteria
ISU55_RS02450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ISU55_RS02455	COG0629	single-stranded DNA binding
ISU55_RS02465	COG1454	alcohol dehydrogenase
ISU55_RS02525	COG1309	transcriptional regulator
ISU55_RS02530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU55_RS02530	COG0493	'glutamate synthase
ISU55_RS02535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU55_RS02540	COG3383	formate dehydrogenase (NAD+) activity
ISU55_RS02555	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ISU55_RS02600	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ISU55_RS02610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ISU55_RS02615	COG1053	succinate dehydrogenase
ISU55_RS02630	COG3264	Mechanosensitive ion channel
ISU55_RS02630	COG1511	domain protein
ISU55_RS02645	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ISU55_RS02660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ISU55_RS02665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ISU55_RS02665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ISU55_RS02670	COG0802	atpase or kinase
ISU55_RS02675	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU55_RS02695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ISU55_RS02700	COG0330	HflC and HflK could
ISU55_RS02705	COG0330	HflC and HflK could
ISU55_RS02710	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ISU55_RS02725	COG0557	exoribonuclease II activity
ISU55_RS02730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU55_RS02735	COG1960	acyl-CoA dehydrogenase activity
ISU55_RS02740	COG3650	response to hydrogen peroxide
ISU55_RS02760	COG1073	alpha beta
ISU55_RS02765	COG0360	Binds together with S18 to 16S ribosomal RNA
ISU55_RS02775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ISU55_RS02795	COG3061	Opacity-associated protein A
ISU55_RS02800	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU55_RS02810	COG0737	Belongs to the 5'-nucleotidase family
ISU55_RS02820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ISU55_RS02830	COG1253	flavin adenine dinucleotide binding
ISU55_RS02840	COG0729	surface antigen
ISU55_RS02845	COG2911	Protein conserved in bacteria
ISU55_RS02850	COG2105	PFAM AIG2 family protein
ISU55_RS02855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ISU55_RS02860	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ISU55_RS02865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ISU55_RS02885	COG3423	Transcriptional regulator
ISU55_RS02895	COG0142	geranyltranstransferase activity
ISU55_RS02910	COG0697	spore germination
ISU55_RS02920	COG0642	Histidine kinase
ISU55_RS02925	COG0745	RESPONSE REGULATOR receiver
ISU55_RS02930	COG2027	D-alanyl-D-alanine carboxypeptidase
ISU55_RS02940	COG1534	Rna-binding protein
ISU55_RS02955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ISU55_RS02965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ISU55_RS02985	COG0195	Participates in both transcription termination and antitermination
ISU55_RS03030	COG0513	Belongs to the DEAD box helicase family
ISU55_RS03050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ISU55_RS03060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU55_RS03070	COG0826	peptidase U32
ISU55_RS03075	COG0826	peptidase U32
ISU55_RS03080	COG3154	lipid carrier protein
ISU55_RS03085	COG3153	acetyltransferase
ISU55_RS03105	COG1653	transport
ISU55_RS03110	COG1175	transmembrane transport
ISU55_RS03115	COG0395	ABC-type sugar transport system, permease component
ISU55_RS03120	COG3842	ATPase activity
ISU55_RS03135	COG0702	epimerase
ISU55_RS03140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ISU55_RS03145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ISU55_RS03150	COG3454	Phosphonate metabolism
ISU55_RS03155	COG4778	phosphonate C-P lyase system protein PhnL
ISU55_RS03160	COG4107	phosphonate C-P lyase system protein PhnK
ISU55_RS03165	COG3627	carbon phosphorus lyase activity
ISU55_RS03170	COG3626	phosphonate metabolism
ISU55_RS03175	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ISU55_RS03180	COG3624	Phosphonate C-P lyase system protein PhnG
ISU55_RS03185	COG2188	Transcriptional regulator
ISU55_RS03200	COG4608	Belongs to the ABC transporter superfamily
ISU55_RS03205	COG0444	Belongs to the ABC transporter superfamily
ISU55_RS03210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU55_RS03215	COG0601	transmembrane transport
ISU55_RS03225	COG2731	YhcH YjgK YiaL family protein
ISU55_RS03235	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ISU55_RS03245	COG0525	valine-tRNA ligase activity
ISU55_RS03250	COG2927	DNA polymerase III (CHI subunit)
ISU55_RS03260	COG0795	lipopolysaccharide-transporting ATPase activity
ISU55_RS03265	COG0795	lipopolysaccharide-transporting ATPase activity
ISU55_RS03275	COG0582	viral genome integration into host DNA
ISU55_RS03325	COG1459	type II secretion system
ISU55_RS03330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU55_RS03335	COG4969	Belongs to the N-Me-Phe pilin family
ISU55_RS03345	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU55_RS03350	COG3725	Membrane protein required for beta-lactamase induction
ISU55_RS03355	COG1113	amino acid transport
ISU55_RS03360	COG2186	Transcriptional regulator
ISU55_RS03365	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ISU55_RS03370	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU55_RS03375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU55_RS03385	COG1049	propionate catabolic process, 2-methylcitrate cycle
ISU55_RS03395	COG0697	spore germination
ISU55_RS03415	COG2132	Multicopper oxidase
ISU55_RS03420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ISU55_RS03425	COG0288	reversible hydration of carbon dioxide
ISU55_RS03430	COG1131	(ABC) transporter
ISU55_RS03435	COG0842	Transport permease protein
ISU55_RS03460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ISU55_RS03465	COG0617	tRNA 3'-terminal CCA addition
ISU55_RS03470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ISU55_RS03485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ISU55_RS03490	COG1643	Atp-dependent helicase
ISU55_RS03495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ISU55_RS03500	COG1120	ATPase activity
ISU55_RS03505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU55_RS03510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS03530	COG2860	membrane
ISU55_RS03550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ISU55_RS03555	COG2205	protein histidine kinase activity
ISU55_RS03555	COG4999	Histidine kinase
ISU55_RS03555	COG3850	Histidine kinase
ISU55_RS03555	COG3437	response regulator, receiver
ISU55_RS03565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ISU55_RS03570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU55_RS03575	COG3956	TIGRFAM MazG family protein
ISU55_RS03595	COG0602	queuosine metabolic process
ISU55_RS03600	COG0720	synthase
ISU55_RS03655	COG0529	Catalyzes the synthesis of activated sulfate
ISU55_RS03695	COG4942	peptidase
ISU55_RS03695	COG1388	LysM domain
ISU55_RS03700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ISU55_RS03710	COG0698	ribose 5-phosphate isomerase
ISU55_RS03715	COG1063	alcohol dehydrogenase
ISU55_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS03725	COG2376	Dihydroxyacetone kinase
ISU55_RS03740	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ISU55_RS03760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS03765	COG1858	cytochrome C peroxidase
ISU55_RS03775	COG4771	TonB-dependent receptor
ISU55_RS03785	COG0024	Methionine aminopeptidase
ISU55_RS03795	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU55_RS03795	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ISU55_RS03800	COG1070	Carbohydrate kinase
ISU55_RS03805	COG3623	hexulose-6-phosphate isomerase
ISU55_RS03810	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS03815	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS03820	COG1129	ABC transporter
ISU55_RS03830	COG0077	Prephenate dehydratase
ISU55_RS03830	COG1605	Chorismate mutase
ISU55_RS03835	COG0287	Prephenate dehydrogenase
ISU55_RS03835	COG1605	Chorismate mutase
ISU55_RS03840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU55_RS03845	COG3279	Response regulator of the LytR AlgR family
ISU55_RS03855	COG3137	Salt-induced outer membrane protein
ISU55_RS03900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ISU55_RS03905	COG4137	Cytochrome C assembly protein
ISU55_RS03910	COG4536	flavin adenine dinucleotide binding
ISU55_RS03925	COG2918	glutathione biosynthetic process
ISU55_RS03930	COG1238	metal cluster binding
ISU55_RS03935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU55_RS03965	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ISU55_RS04005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU55_RS04010	COG3958	Transketolase
ISU55_RS04015	COG3959	Transketolase, thiamine diphosphate binding domain
ISU55_RS04020	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS04025	COG1129	ABC transporter
ISU55_RS04035	COG1879	ABC-type sugar transport system periplasmic component
ISU55_RS04045	COG3783	Cytochrome b(562)
ISU55_RS04050	COG3038	cytochrome b561
ISU55_RS04055	COG3381	protein complex oligomerization
ISU55_RS04060	COG3302	dmso reductase anchor subunit
ISU55_RS04065	COG0437	4 iron, 4 sulfur cluster binding
ISU55_RS04070	COG0243	molybdopterin cofactor binding
ISU55_RS04075	COG0235	Class ii aldolase
ISU55_RS04080	COG1349	DNA-binding transcription factor activity
ISU55_RS04095	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ISU55_RS04100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU55_RS04105	COG0564	pseudouridine synthase activity
ISU55_RS04115	COG0542	response to heat
ISU55_RS04145	COG5544	Lipoprotein
ISU55_RS04150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ISU55_RS04155	COG1042	CoA-binding domain protein
ISU55_RS04155	COG0045	succinate-CoA ligase (ADP-forming) activity
ISU55_RS04155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU55_RS04160	COG3148	PFAM DTW domain containing protein
ISU55_RS04165	COG3118	belongs to the thioredoxin family
ISU55_RS04170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU55_RS04175	COG2814	Major facilitator Superfamily
ISU55_RS04180	COG1566	PFAM secretion protein HlyD family protein
ISU55_RS04185	COG1846	Transcriptional regulator
ISU55_RS04195	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ISU55_RS04200	COG2814	Major facilitator Superfamily
ISU55_RS04235	COG0765	amino acid transport
ISU55_RS04245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU55_RS04260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ISU55_RS04285	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
ISU55_RS04295	COG1960	acyl-CoA dehydrogenase activity
ISU55_RS04305	COG0121	glutamine amidotransferase
ISU55_RS04310	COG3034	peptidoglycan biosynthetic process
ISU55_RS04320	COG1805	sodium ion transport
ISU55_RS04325	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ISU55_RS04345	COG1477	protein flavinylation
ISU55_RS04365	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU55_RS04370	COG0583	DNA-binding transcription factor activity
ISU55_RS04430	COG2226	methyltransferase
ISU55_RS04455	COG1940	carbohydrate kinase activity
ISU55_RS04460	COG0419	ATPase involved in DNA repair
ISU55_RS04465	COG0420	3'-5' exonuclease activity
ISU55_RS04470	COG0745	RESPONSE REGULATOR receiver
ISU55_RS04475	COG5002	protein histidine kinase activity
ISU55_RS04495	COG0366	Alpha amylase catalytic
ISU55_RS04515	COG0450	alkyl hydroperoxide reductase
ISU55_RS04535	COG1862	Preprotein translocase
ISU55_RS04540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU55_RS04545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ISU55_RS04570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU55_RS04570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ISU55_RS04585	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ISU55_RS04590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ISU55_RS04605	COG0142	geranyltranstransferase activity
ISU55_RS04620	COG0693	protein deglycase activity
ISU55_RS04625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ISU55_RS04635	COG2814	Major facilitator Superfamily
ISU55_RS04645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ISU55_RS04650	COG1845	cytochrome c oxidase, subunit III
ISU55_RS04655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ISU55_RS04660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ISU55_RS04670	COG2223	nitrite transmembrane transporter activity
ISU55_RS04675	COG3056	Lipoprotein
ISU55_RS04680	COG0271	Belongs to the BolA IbaG family
ISU55_RS04700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ISU55_RS04705	COG0776	regulation of translation
ISU55_RS04715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ISU55_RS04720	COG1555	photosystem II stabilization
ISU55_RS04725	COG0824	Thioesterase
ISU55_RS04735	COG4533	DNA binding
ISU55_RS04750	COG1522	sequence-specific DNA binding
ISU55_RS04755	COG1132	(ABC) transporter
ISU55_RS04760	COG1132	(ABC) transporter
ISU55_RS04765	COG0347	Belongs to the P(II) protein family
ISU55_RS04770	COG0004	ammonium transporteR
ISU55_RS04775	COG1946	Acyl-CoA thioesterase
ISU55_RS04780	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ISU55_RS04785	COG3695	enzyme binding
ISU55_RS04810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU55_RS04820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU55_RS04825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU55_RS04830	COG1309	transcriptional regulator
ISU55_RS04835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ISU55_RS04840	COG3264	Mechanosensitive ion channel
ISU55_RS04840	COG1196	nuclear chromosome segregation
ISU55_RS04855	COG2832	Protein of unknown function (DUF454)
ISU55_RS04865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ISU55_RS04895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU55_RS04895	COG0543	2 iron, 2 sulfur cluster binding
ISU55_RS04915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU55_RS04955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU55_RS04975	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ISU55_RS04980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU55_RS04985	COG4651	solute:proton antiporter activity
ISU55_RS04985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU55_RS04990	COG2223	nitrite transmembrane transporter activity
ISU55_RS05005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ISU55_RS05010	COG3735	TraB family
ISU55_RS05015	COG2217	Heavy metal translocating P-type atpase
ISU55_RS05020	COG0789	Transcriptional regulator
ISU55_RS05025	COG1585	Membrane protein implicated in regulation of membrane protease activity
ISU55_RS05030	COG0330	HflC and HflK could
ISU55_RS05035	COG3118	belongs to the thioredoxin family
ISU55_RS05040	COG0300	oxidoreductase activity
ISU55_RS05045	COG2755	lipolytic protein G-D-S-L family
ISU55_RS05050	COG4181	ATPase activity
ISU55_RS05055	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ISU55_RS05060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ISU55_RS05065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ISU55_RS05075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU55_RS05090	COG2501	S4 domain
ISU55_RS05125	COG0582	viral genome integration into host DNA
ISU55_RS05135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ISU55_RS05140	COG4589	Belongs to the CDS family
ISU55_RS05150	COG2267	carboxylic ester hydrolase activity
ISU55_RS05155	COG0671	phosphoesterase, PA-phosphatase related
ISU55_RS05155	COG2453	phosphatase
ISU55_RS05185	COG0667	Aldo Keto reductase
ISU55_RS05190	COG0656	L-ascorbic acid biosynthetic process
ISU55_RS05200	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU55_RS05215	COG3328	transposase activity
ISU55_RS05270	COG3423	Transcriptional regulator
ISU55_RS05275	COG4953	penicillin-binding protein 1C
ISU55_RS05285	COG2373	Large extracellular alpha-helical protein
ISU55_RS05305	COG3962	Belongs to the TPP enzyme family
ISU55_RS05320	COG1129	ABC transporter
ISU55_RS05325	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS05330	COG0673	inositol 2-dehydrogenase activity
ISU55_RS05335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU55_RS05345	COG3718	enzyme involved in inositol metabolism
ISU55_RS05355	COG5265	(ABC) transporter
ISU55_RS05380	COG2197	response regulator
ISU55_RS05385	COG1278	Cold shock
ISU55_RS05395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU55_RS05400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ISU55_RS05420	COG1686	Belongs to the peptidase S11 family
ISU55_RS05425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU55_RS05430	COG0772	Belongs to the SEDS family
ISU55_RS05435	COG0768	penicillin binding
ISU55_RS05445	COG0799	negative regulation of ribosome biogenesis
ISU55_RS05455	COG1466	dna polymerase III delta subunit
ISU55_RS05470	COG2888	peptidyl-tyrosine sulfation
ISU55_RS05475	COG1126	abc transporter atp-binding protein
ISU55_RS05480	COG0765	amino acid transport
ISU55_RS05485	COG0765	amino acid transport
ISU55_RS05495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ISU55_RS05500	COG4535	Mg2 and Co2 transporter CorC
ISU55_RS05510	COG1702	phosphate starvation-inducible protein PhoH
ISU55_RS05515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ISU55_RS05520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU55_RS05555	COG0367	asparagine synthase
ISU55_RS05560	COG0647	UMP catabolic process
ISU55_RS05565	COG1940	carbohydrate kinase activity
ISU55_RS05565	COG1846	Transcriptional regulator
ISU55_RS05570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ISU55_RS05580	COG1263	PTS System
ISU55_RS05580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU55_RS05580	COG2190	(PTS) system
ISU55_RS05605	COG0735	belongs to the Fur family
ISU55_RS05620	COG0596	Alpha beta hydrolase
ISU55_RS05630	COG0582	viral genome integration into host DNA
ISU55_RS05665	COG2113	Glycine betaine
ISU55_RS05670	COG4176	ABC-type proline glycine betaine transport system permease component
ISU55_RS05675	COG4175	Glycine betaine
ISU55_RS05680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ISU55_RS05720	COG1278	Cold shock
ISU55_RS05725	COG0747	negative chemotaxis
ISU55_RS05735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU55_RS05740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ISU55_RS05745	COG1124	(ABC) transporter
ISU55_RS05750	COG0831	urea catabolic process
ISU55_RS05775	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ISU55_RS05785	COG4413	Urea transporter
ISU55_RS05790	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU55_RS05800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ISU55_RS05810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ISU55_RS05820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU55_RS05825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ISU55_RS05830	COG1447	Phosphotransferase system cellobiose-specific component IIA
ISU55_RS05835	COG1917	Cupin 2, conserved barrel domain protein
ISU55_RS05835	COG2169	Transcriptional regulator
ISU55_RS05850	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ISU55_RS05855	COG0033	Phosphoglucomutase
ISU55_RS05870	COG0745	RESPONSE REGULATOR receiver
ISU55_RS05875	COG2205	protein histidine kinase activity
ISU55_RS05910	COG3272	Protein of unknown function (DUF1722)
ISU55_RS05920	COG5212	phosphodiesterase
ISU55_RS05925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ISU55_RS05940	COG1984	allophanate hydrolase subunit 2
ISU55_RS05985	COG0513	Belongs to the DEAD box helicase family
ISU55_RS05995	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ISU55_RS06010	COG3026	antisigma factor binding
ISU55_RS06015	COG3086	response to oxidative stress
ISU55_RS06050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ISU55_RS06065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU55_RS06070	COG1737	Transcriptional regulator
ISU55_RS06080	COG0560	Phosphoserine phosphatase
ISU55_RS06125	COG2205	protein histidine kinase activity
ISU55_RS06130	COG3170	Tfp pilus assembly protein FimV
ISU55_RS06135	COG2204	response regulator
ISU55_RS06140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU55_RS06140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ISU55_RS06145	COG0347	Belongs to the P(II) protein family
ISU55_RS06170	COG1017	nitric oxide dioxygenase activity
ISU55_RS06170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU55_RS06190	COG2814	Major facilitator Superfamily
ISU55_RS06195	COG3711	transcriptional antiterminator
ISU55_RS06200	COG3683	transport system, periplasmic component
ISU55_RS06205	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ISU55_RS06225	COG1104	cysteine desulfurase activity
ISU55_RS06230	COG0822	iron-sulfur transferase activity
ISU55_RS06250	COG0633	Ferredoxin
ISU55_RS06255	COG2975	iron-sulfur cluster assembly
ISU55_RS06280	COG3468	outer membrane autotransporter barrel domain protein
ISU55_RS06285	COG3468	outer membrane autotransporter barrel domain protein
ISU55_RS06325	COG2976	Protein conserved in bacteria
ISU55_RS06330	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU55_RS06345	COG1645	bacterial-type flagellum-dependent swarming motility
ISU55_RS06355	COG0517	IMP dehydrogenase activity
ISU55_RS06355	COG0516	GMP reductase activity
ISU55_RS06400	COG3328	transposase activity
ISU55_RS06415	COG0351	phosphomethylpyrimidine kinase
ISU55_RS06440	COG0826	peptidase U32
ISU55_RS06445	COG3422	double-strand break repair
ISU55_RS06450	COG0745	RESPONSE REGULATOR receiver
ISU55_RS06480	COG3842	ATPase activity
ISU55_RS06490	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ISU55_RS06500	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU55_RS06505	COG1177	transmembrane transport
ISU55_RS06510	COG0443	Heat shock 70 kDa protein
ISU55_RS06515	COG2239	Acts as a magnesium transporter
ISU55_RS06530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ISU55_RS06540	COG0581	inorganic phosphate transmembrane transporter activity
ISU55_RS06555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU55_RS06560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ISU55_RS06585	COG1393	Belongs to the ArsC family
ISU55_RS06590	COG4783	chaperone-mediated protein folding
ISU55_RS06595	COG0628	permease
ISU55_RS06605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ISU55_RS06610	COG2716	regulation of RNA biosynthetic process
ISU55_RS06620	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ISU55_RS06635	COG2321	neutral zinc metallopeptidase
ISU55_RS06655	COG1876	peptidase activity
ISU55_RS06665	COG1393	Belongs to the ArsC family
ISU55_RS06680	COG1175	transmembrane transport
ISU55_RS06685	COG3842	ATPase activity
ISU55_RS06695	COG3119	arylsulfatase activity
ISU55_RS06700	COG0641	radical SAM
ISU55_RS06705	COG1988	membrane-bound metal-dependent
ISU55_RS06715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU55_RS06725	COG2197	response regulator
ISU55_RS06730	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU55_RS06730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ISU55_RS06735	COG3062	negative regulation of establishment of protein localization
ISU55_RS06745	COG3043	anaerobic respiration
ISU55_RS06750	COG3005	denitrification pathway
ISU55_RS06805	COG3111	PFAM Bacterial OB fold (BOF) protein
ISU55_RS06815	COG2837	iron assimilation
ISU55_RS06820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ISU55_RS06830	COG4886	Leucine-rich repeat (LRR) protein
ISU55_RS06840	COG2731	YhcH YjgK YiaL family protein
ISU55_RS06845	COG1737	Transcriptional regulator
ISU55_RS06855	COG4150	thiosulfate binding
ISU55_RS06860	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ISU55_RS06865	COG4208	sulfate ABC transporter
ISU55_RS06870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ISU55_RS06885	COG0745	RESPONSE REGULATOR receiver
ISU55_RS06890	COG5002	protein histidine kinase activity
ISU55_RS06890	COG3850	Histidine kinase
ISU55_RS06900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ISU55_RS06920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ISU55_RS06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU55_RS06940	COG0745	RESPONSE REGULATOR receiver
ISU55_RS06945	COG2205	protein histidine kinase activity
ISU55_RS06975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS06985	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ISU55_RS07000	COG3530	Putative quorum-sensing-regulated virulence factor
ISU55_RS07060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU55_RS07075	COG0667	Aldo Keto reductase
ISU55_RS07100	COG0436	Aminotransferase
ISU55_RS07105	COG3038	cytochrome b561
ISU55_RS07135	COG3381	protein complex oligomerization
ISU55_RS07140	COG3302	dmso reductase anchor subunit
ISU55_RS07145	COG0437	4 iron, 4 sulfur cluster binding
ISU55_RS07150	COG0243	molybdopterin cofactor binding
ISU55_RS07245	COG3121	Chaperone
ISU55_RS07250	COG3188	usher protein
ISU55_RS07255	COG3328	transposase activity
ISU55_RS07260	COG3188	usher protein
ISU55_RS07350	COG2824	Alkylphosphonate utilization operon protein PhnA
ISU55_RS07360	COG1704	LemA family
ISU55_RS07380	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU55_RS07385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU55_RS07390	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ISU55_RS07400	COG1138	Cytochrome C-type biogenesis protein
ISU55_RS07405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ISU55_RS07410	COG3088	subunit of a heme lyase
ISU55_RS07410	COG4235	cytochrome complex assembly
ISU55_RS07415	COG4235	cytochrome complex assembly
ISU55_RS07415	COG3088	subunit of a heme lyase
ISU55_RS07430	COG3691	Protein conserved in bacteria
ISU55_RS07445	COG2062	phosphohistidine phosphatase, SixA
ISU55_RS07460	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU55_RS07475	COG0730	response to heat
ISU55_RS07480	COG3101	peptidyl-lysine hydroxylation
ISU55_RS07495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU55_RS07500	COG1794	racemase activity, acting on amino acids and derivatives
ISU55_RS07515	COG0697	spore germination
ISU55_RS07530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU55_RS07540	COG0586	Pfam SNARE associated Golgi protein
ISU55_RS07550	COG0285	dihydrofolate synthase activity
ISU55_RS07555	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ISU55_RS07560	COG1286	toxin biosynthetic process
ISU55_RS07565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ISU55_RS07575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS07580	COG4215	(ABC) transporter
ISU55_RS07585	COG4160	amino acid transport
ISU55_RS07590	COG4598	ABC transporter
ISU55_RS07595	COG1090	epimerase
ISU55_RS07605	COG0622	Phosphoesterase
ISU55_RS07610	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ISU55_RS07615	COG3037	sugar-specific permease SgaT UlaA
ISU55_RS07620	COG3328	transposase activity
ISU55_RS07635	COG1609	Transcriptional regulator
ISU55_RS07640	COG0280	phosphate acetyltransferase
ISU55_RS07640	COG0857	belongs to the CobB CobQ family
ISU55_RS07660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU55_RS07665	COG0471	metal ion transport
ISU55_RS07665	COG0490	domain, Protein
ISU55_RS07675	COG0436	Aminotransferase
ISU55_RS07680	COG0583	DNA-binding transcription factor activity
ISU55_RS07690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU55_RS07710	COG1034	ATP synthesis coupled electron transport
ISU55_RS07725	COG0839	Belongs to the complex I subunit 6 family
ISU55_RS07735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ISU55_RS07740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU55_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS07765	COG3265	gluconokinase activity
ISU55_RS07780	COG1649	PFAM Uncharacterised BCR, COG1649
ISU55_RS07785	COG1609	Transcriptional regulator
ISU55_RS07790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU55_RS07805	COG0129	dihydroxy-acid dehydratase activity
ISU55_RS07810	COG4575	ribosome binding
ISU55_RS07820	COG1169	isochorismate synthase
ISU55_RS07835	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ISU55_RS07850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ISU55_RS07885	COG1126	abc transporter atp-binding protein
ISU55_RS07890	COG0765	amino acid transport
ISU55_RS07895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS07925	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ISU55_RS07945	COG1063	alcohol dehydrogenase
ISU55_RS07950	COG1879	ABC-type sugar transport system periplasmic component
ISU55_RS07955	COG1129	ABC transporter
ISU55_RS07960	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS07965	COG1609	Transcriptional regulator
ISU55_RS07970	COG0583	DNA-binding transcription factor activity
ISU55_RS07975	COG0473	3-isopropylmalate dehydrogenase activity
ISU55_RS07985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU55_RS07995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU55_RS08000	COG2831	hemolysin activation secretion protein
ISU55_RS08045	COG3210	domain, Protein
ISU55_RS08055	COG3842	ATPase activity
ISU55_RS08065	COG1609	Transcriptional regulator
ISU55_RS08080	COG0395	ABC-type sugar transport system, permease component
ISU55_RS08085	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ISU55_RS08105	COG0668	transmembrane transport
ISU55_RS08110	COG1518	maintenance of DNA repeat elements
ISU55_RS08115	COG1203	CRISPR-associated helicase, Cas3
ISU55_RS08140	COG0667	Aldo Keto reductase
ISU55_RS08160	COG0583	DNA-binding transcription factor activity
ISU55_RS08165	COG2771	luxR family
ISU55_RS08170	COG3916	Acyl-homoserine-lactone synthase
ISU55_RS08190	COG0628	permease
ISU55_RS08210	COG3328	transposase activity
ISU55_RS08220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ISU55_RS08240	COG3328	transposase activity
ISU55_RS08245	COG1530	ribonuclease E activity
ISU55_RS08250	COG0564	pseudouridine synthase activity
ISU55_RS08255	COG0424	maF-like protein
ISU55_RS08260	COG1399	metal-binding, possibly nucleic acid-binding protein
ISU55_RS08265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ISU55_RS08295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU55_RS08305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ISU55_RS08310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ISU55_RS08320	COG0470	DNA polymerase III
ISU55_RS08325	COG0084	hydrolase, TatD family'
ISU55_RS08330	COG1263	PTS System
ISU55_RS08330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU55_RS08340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ISU55_RS08345	COG0537	adenosine 5'-monophosphoramidase activity
ISU55_RS08350	COG5633	Lipoprotein
ISU55_RS08365	COG1472	Belongs to the glycosyl hydrolase 3 family
ISU55_RS08375	COG1252	NADH dehydrogenase
ISU55_RS08390	COG3328	transposase activity
ISU55_RS08395	COG3134	Outer membrane lipoprotein
ISU55_RS08400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ISU55_RS08405	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU55_RS08415	COG4591	ABC-type transport system involved in lipoprotein release permease component
ISU55_RS08420	COG1940	carbohydrate kinase activity
ISU55_RS08440	COG2850	peptidyl-arginine hydroxylation
ISU55_RS08450	COG0745	RESPONSE REGULATOR receiver
ISU55_RS08460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ISU55_RS08480	COG1187	pseudouridine synthase activity
ISU55_RS08485	COG0538	isocitrate dehydrogenase activity
ISU55_RS08500	COG0840	transmembrane signaling receptor activity
ISU55_RS08505	COG0702	epimerase
ISU55_RS08510	COG1733	regulation of RNA biosynthetic process
ISU55_RS08535	COG1522	sequence-specific DNA binding
ISU55_RS08550	COG0604	alcohol dehydrogenase
ISU55_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS08550	COG3321	synthase
ISU55_RS08585	COG1285	pathogenesis
ISU55_RS08610	COG1360	Flagellar Motor Protein
ISU55_RS08615	COG0643	Histidine kinase
ISU55_RS08615	COG2198	Histidine kinase
ISU55_RS08620	COG0835	chemotaxis
ISU55_RS08625	COG2271	Major facilitator Superfamily
ISU55_RS08630	COG0251	oxidation-reduction process
ISU55_RS08640	COG2964	Protein conserved in bacteria
ISU55_RS08660	COG0840	transmembrane signaling receptor activity
ISU55_RS08665	COG0840	transmembrane signaling receptor activity
ISU55_RS08670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ISU55_RS08680	COG0745	RESPONSE REGULATOR receiver
ISU55_RS08685	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ISU55_RS08690	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU55_RS08700	COG5295	Hep Hag repeat protein
ISU55_RS08710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ISU55_RS08765	COG3121	Chaperone
ISU55_RS08785	COG3008	intermembrane lipid transfer
ISU55_RS08790	COG2995	paraquat-inducible protein a
ISU55_RS08795	COG1956	GAF domain-containing protein
ISU55_RS08805	COG0793	Belongs to the peptidase S41A family
ISU55_RS08815	COG3539	Fimbrial protein
ISU55_RS08820	COG3121	Chaperone
ISU55_RS08835	COG3121	Chaperone
ISU55_RS08840	COG2814	Major facilitator Superfamily
ISU55_RS08845	COG0823	Involved in the tonB-independent uptake of proteins
ISU55_RS08855	COG3023	N-Acetylmuramoyl-L-alanine amidase
ISU55_RS08860	COG1823	symporter activity
ISU55_RS08865	COG1988	membrane-bound metal-dependent
ISU55_RS08870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU55_RS08875	COG1653	transport
ISU55_RS08880	COG3842	ATPase activity
ISU55_RS08885	COG0395	ABC-type sugar transport system, permease component
ISU55_RS08890	COG1175	transmembrane transport
ISU55_RS08900	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS08910	COG1917	Cupin 2, conserved barrel domain protein
ISU55_RS08915	COG3328	transposase activity
ISU55_RS08920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU55_RS08930	COG3001	Fructosamine kinase
ISU55_RS08940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU55_RS08945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU55_RS08950	COG1121	(ABC) transporter
ISU55_RS08955	COG0803	Belongs to the bacterial solute-binding protein 9 family
ISU55_RS08975	COG4249	Peptidase C14 caspase catalytic subunit p20
ISU55_RS09010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ISU55_RS09010	COG0072	phenylalanine-tRNA ligase activity
ISU55_RS09015	COG0776	regulation of translation
ISU55_RS09030	COG0386	Belongs to the glutathione peroxidase family
ISU55_RS09080	COG0791	NLP P60 protein
ISU55_RS09105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU55_RS09105	COG0574	Belongs to the PEP-utilizing enzyme family
ISU55_RS09115	COG0628	permease
ISU55_RS09120	COG0247	lactate metabolic process
ISU55_RS09120	COG0277	FAD linked oxidase domain protein
ISU55_RS09125	COG2050	protein possibly involved in aromatic compounds catabolism
ISU55_RS09130	COG0316	Belongs to the HesB IscA family
ISU55_RS09135	COG0719	Fe-S assembly protein
ISU55_RS09140	COG0396	ATPase activity
ISU55_RS09145	COG0719	Fe-S assembly protein
ISU55_RS09160	COG1376	ErfK ybiS ycfS ynhG family protein
ISU55_RS09160	COG1388	LysM domain
ISU55_RS09215	COG0307	riboflavin synthase, alpha
ISU55_RS09220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ISU55_RS09225	COG2814	Major facilitator Superfamily
ISU55_RS09230	COG0583	DNA-binding transcription factor activity
ISU55_RS09250	COG0791	NLP P60 protein
ISU55_RS09255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ISU55_RS09265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ISU55_RS09270	COG0346	lactoylglutathione lyase activity
ISU55_RS09280	COG1309	transcriptional regulator
ISU55_RS09285	COG2194	sulfuric ester hydrolase activity
ISU55_RS09295	COG3133	Outer membrane lipoprotein
ISU55_RS09305	COG3895	Periplasmic Protein
ISU55_RS09325	COG0625	glutathione transferase activity
ISU55_RS09340	COG3104	oligopeptide transport
ISU55_RS09345	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU55_RS09345	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ISU55_RS09350	COG4172	Belongs to the ABC transporter superfamily
ISU55_RS09360	COG4171	peptide transport system, permease
ISU55_RS09365	COG4168	peptide transport system, permease
ISU55_RS09370	COG4166	transmembrane transport
ISU55_RS09380	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ISU55_RS09385	COG1842	Phage shock protein A
ISU55_RS09395	COG1983	PspC domain protein
ISU55_RS09405	COG3106	COG3106 Predicted ATPase
ISU55_RS09415	COG5654	RES domain protein
ISU55_RS09420	COG5642	Protein of unknown function (DUF2384)
ISU55_RS09450	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ISU55_RS09455	COG4948	Mandelate Racemase Muconate Lactonizing
ISU55_RS09460	COG2866	Carboxypeptidase
ISU55_RS09465	COG4166	transmembrane transport
ISU55_RS09480	COG0657	acetylesterase activity
ISU55_RS09490	COG1013	pyruvate-flavodoxin oxidoreductase activity
ISU55_RS09490	COG0674	pyruvate-flavodoxin oxidoreductase activity
ISU55_RS09490	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ISU55_RS09490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ISU55_RS09500	COG1285	pathogenesis
ISU55_RS09505	COG3042	response to heat
ISU55_RS09510	COG3187	Heat shock protein
ISU55_RS09515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ISU55_RS09520	COG2911	Protein conserved in bacteria
ISU55_RS09530	COG3784	Protein of unknown function (DUF1318)
ISU55_RS09535	COG0246	Mannitol dehydrogenase
ISU55_RS09540	COG2390	Transcriptional regulator
ISU55_RS09550	COG1643	Atp-dependent helicase
ISU55_RS09565	COG3591	Belongs to the peptidase S1B family
ISU55_RS09605	COG1012	belongs to the aldehyde dehydrogenase family
ISU55_RS09605	COG1454	alcohol dehydrogenase
ISU55_RS09610	COG2095	MarC family integral membrane protein
ISU55_RS09620	COG0601	transmembrane transport
ISU55_RS09625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU55_RS09630	COG0444	Belongs to the ABC transporter superfamily
ISU55_RS09635	COG4608	Belongs to the ABC transporter superfamily
ISU55_RS09680	COG2350	Protein conserved in bacteria
ISU55_RS09685	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ISU55_RS09690	COG3328	transposase activity
ISU55_RS09725	COG3047	cAMP biosynthetic process
ISU55_RS09745	COG0135	phosphoribosylanthranilate isomerase activity
ISU55_RS09745	COG0134	indole-3-glycerol-phosphate synthase activity
ISU55_RS09755	COG0512	Glutamine amidotransferase of anthranilate synthase
ISU55_RS09775	COG0009	L-threonylcarbamoyladenylate synthase
ISU55_RS09780	COG1187	pseudouridine synthase activity
ISU55_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS09795	COG0616	signal peptide processing
ISU55_RS09815	COG0583	DNA-binding transcription factor activity
ISU55_RS09825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ISU55_RS09835	COG0671	phosphoesterase, PA-phosphatase related
ISU55_RS09840	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ISU55_RS09845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ISU55_RS09860	COG0023	Translation Initiation Factor
ISU55_RS09880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ISU55_RS09885	COG2879	small protein
ISU55_RS09890	COG1966	Carbon starvation protein
ISU55_RS09900	COG2271	Major facilitator Superfamily
ISU55_RS09905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU55_RS09910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ISU55_RS09920	COG4659	FMN binding
ISU55_RS09925	COG4658	electron transport chain
ISU55_RS09930	COG2207	Transcriptional regulator
ISU55_RS09930	COG3708	Transcriptional regulator
ISU55_RS09960	COG1132	(ABC) transporter
ISU55_RS09970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU55_RS09975	COG2274	protein secretion by the type I secretion system
ISU55_RS09990	COG1879	ABC-type sugar transport system periplasmic component
ISU55_RS09995	COG1129	ABC transporter
ISU55_RS10000	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS10010	COG0673	inositol 2-dehydrogenase activity
ISU55_RS10015	COG0385	Bile acid
ISU55_RS10025	COG5339	Protein conserved in bacteria
ISU55_RS10035	COG0114	fumarate hydratase activity
ISU55_RS10045	COG2814	Major facilitator Superfamily
ISU55_RS10050	COG0583	DNA-binding transcription factor activity
ISU55_RS10055	COG1940	carbohydrate kinase activity
ISU55_RS10060	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ISU55_RS10065	COG0038	chloride channel
ISU55_RS10070	COG1609	Transcriptional regulator
ISU55_RS10090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU55_RS10100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ISU55_RS10130	COG0028	Belongs to the TPP enzyme family
ISU55_RS10135	COG0440	acetolactate synthase activity
ISU55_RS10140	COG1011	Hydrolase
ISU55_RS10155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU55_RS10160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ISU55_RS10165	COG0589	response to stress
ISU55_RS10170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ISU55_RS10175	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ISU55_RS10185	COG0531	amino acid
ISU55_RS10195	COG0745	RESPONSE REGULATOR receiver
ISU55_RS10200	COG2205	protein histidine kinase activity
ISU55_RS10205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ISU55_RS10240	COG0745	RESPONSE REGULATOR receiver
ISU55_RS10250	COG0788	formyltetrahydrofolate deformylase activity
ISU55_RS10255	COG3328	transposase activity
ISU55_RS10275	COG0583	DNA-binding transcription factor activity
ISU55_RS10280	COG0708	Exodeoxyribonuclease III
ISU55_RS10285	COG0494	nUDIX hydrolase
ISU55_RS10295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ISU55_RS10300	COG0709	Synthesizes selenophosphate from selenide and ATP
ISU55_RS10305	COG0778	Nitroreductase
ISU55_RS10310	COG0616	signal peptide processing
ISU55_RS10315	COG0252	asparaginase activity
ISU55_RS10320	COG1335	isochorismatase
ISU55_RS10325	COG3139	Protein of unknown function (DUF1315)
ISU55_RS10345	COG3713	MltA-interacting MipA family protein
ISU55_RS10350	COG2766	serine protein kinase
ISU55_RS10365	COG0583	DNA-binding transcription factor activity
ISU55_RS10375	COG2814	Major facilitator Superfamily
ISU55_RS10385	COG2719	SpoVR family
ISU55_RS10415	COG1104	cysteine desulfurase activity
ISU55_RS10425	COG3328	transposase activity
ISU55_RS10585	COG3328	transposase activity
ISU55_RS10685	COG0582	viral genome integration into host DNA
ISU55_RS10695	COG0179	Fumarylacetoacetate (FAA) hydrolase
ISU55_RS10700	COG2951	lytic endotransglycosylase activity
ISU55_RS10715	COG2894	cell division
ISU55_RS10720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ISU55_RS10725	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ISU55_RS10730	COG0318	PFAM AMP-dependent synthetase and ligase
ISU55_RS10740	COG3065	identical protein binding
ISU55_RS10750	COG1199	ATP-dependent helicase activity
ISU55_RS10755	COG0251	oxidation-reduction process
ISU55_RS10770	COG0800	Aldolase
ISU55_RS10775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ISU55_RS10780	COG1737	Transcriptional regulator
ISU55_RS10785	COG0469	pyruvate kinase activity
ISU55_RS10795	COG1560	Kdo2-lipid A biosynthetic process
ISU55_RS10800	COG0739	heme binding
ISU55_RS10805	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ISU55_RS10815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ISU55_RS10840	COG0494	nUDIX hydrolase
ISU55_RS10850	COG1801	Protein of unknown function DUF72
ISU55_RS10855	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ISU55_RS10875	COG3102	Protein conserved in bacteria
ISU55_RS10895	COG0728	peptidoglycan biosynthetic process
ISU55_RS10905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ISU55_RS10920	COG3381	protein complex oligomerization
ISU55_RS10935	COG1940	carbohydrate kinase activity
ISU55_RS10940	COG0584	glycerophosphoryl diester phosphodiesterase
ISU55_RS10960	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU55_RS10965	COG3833	ABC-type maltose transport systems, permease component
ISU55_RS10985	COG0659	secondary active sulfate transmembrane transporter activity
ISU55_RS11005	COG2890	protein-(glutamine-N5) methyltransferase activity
ISU55_RS11030	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ISU55_RS11045	COG0012	GTP binding
ISU55_RS11095	COG5002	protein histidine kinase activity
ISU55_RS11140	COG0500	methyltransferase
ISU55_RS11160	COG3328	transposase activity
ISU55_RS11205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU55_RS11210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU55_RS11215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ISU55_RS11230	COG0402	S-adenosylhomocysteine deaminase activity
ISU55_RS11280	COG3842	ATPase activity
ISU55_RS11285	COG0395	ABC-type sugar transport system, permease component
ISU55_RS11290	COG1175	transmembrane transport
ISU55_RS11300	COG0673	inositol 2-dehydrogenase activity
ISU55_RS11305	COG2188	Transcriptional regulator
ISU55_RS11430	COG2197	response regulator
ISU55_RS11440	COG3136	membrane protein required for alginate biosynthesis
ISU55_RS11460	COG1113	amino acid transport
ISU55_RS11480	COG2822	iron ion transport
ISU55_RS11485	COG0672	)-iron permease
ISU55_RS11500	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU55_RS11500	COG0506	proline dehydrogenase activity
ISU55_RS11500	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ISU55_RS11515	COG1126	abc transporter atp-binding protein
ISU55_RS11520	COG0765	amino acid transport
ISU55_RS11525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS11540	COG1191	sigma factor activity
ISU55_RS11570	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ISU55_RS11575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ISU55_RS11580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ISU55_RS11600	COG1677	Flagellar hook-basal body complex protein FliE
ISU55_RS11620	COG1157	protein secretion by the type III secretion system
ISU55_RS11635	COG1580	Controls the rotational direction of flagella during chemotaxis
ISU55_RS11660	COG1987	bacterial-type flagellum assembly
ISU55_RS11680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU55_RS11685	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS11690	COG1129	ABC transporter
ISU55_RS11700	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS11705	COG3347	Dehydrogenase
ISU55_RS11710	COG2390	Transcriptional regulator
ISU55_RS11720	COG1256	bacterial-type flagellum assembly
ISU55_RS11760	COG1558	bacterial-type flagellum-dependent cell motility
ISU55_RS11765	COG1815	bacterial-type flagellum-dependent cell motility
ISU55_RS11775	COG2747	anti-sigma28 factor FlgM
ISU55_RS11780	COG3418	PFAM FlgN family protein
ISU55_RS11805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU55_RS11810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU55_RS11835	COG2372	response to copper ion
ISU55_RS11840	COG1528	Iron-storage protein
ISU55_RS11855	COG1770	oligopeptidase
ISU55_RS11870	COG3141	response to X-ray
ISU55_RS11875	COG0513	Belongs to the DEAD box helicase family
ISU55_RS11900	COG1760	l-serine dehydratase
ISU55_RS11905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ISU55_RS11910	COG2368	4-hydroxyphenylacetate
ISU55_RS11925	COG3971	2-oxopent-4-enoate hydratase activity
ISU55_RS11935	COG3384	dioxygenase
ISU55_RS11940	COG1012	belongs to the aldehyde dehydrogenase family
ISU55_RS11955	COG1846	Transcriptional regulator
ISU55_RS11960	COG1253	flavin adenine dinucleotide binding
ISU55_RS11965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS11965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU55_RS11970	COG3715	PTS system
ISU55_RS11975	COG3716	PTS system mannose fructose sorbose family IID component
ISU55_RS12025	COG1132	(ABC) transporter
ISU55_RS12035	COG2207	Transcriptional regulator
ISU55_RS12070	COG1113	amino acid transport
ISU55_RS12090	COG1496	oxidoreductase activity
ISU55_RS12095	COG2226	methyltransferase
ISU55_RS12135	COG3328	transposase activity
ISU55_RS12140	COG2223	nitrite transmembrane transporter activity
ISU55_RS12160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ISU55_RS12185	COG3122	Protein conserved in bacteria
ISU55_RS12205	COG0534	Mate efflux family protein
ISU55_RS12220	COG4948	Mandelate Racemase Muconate Lactonizing
ISU55_RS12230	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS12235	COG3011	Protein conserved in bacteria
ISU55_RS12240	COG2271	Major facilitator Superfamily
ISU55_RS12245	COG1470	cell adhesion involved in biofilm formation
ISU55_RS12245	COG1388	LysM domain
ISU55_RS12250	COG3328	transposase activity
ISU55_RS12265	COG2925	Exonuclease
ISU55_RS12275	COG0531	amino acid
ISU55_RS12280	COG0371	Dehydrogenase
ISU55_RS12285	COG1129	ABC transporter
ISU55_RS12290	COG1129	ABC transporter
ISU55_RS12295	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS12310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU55_RS12325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ISU55_RS12335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU55_RS12335	COG0131	Imidazoleglycerol-phosphate dehydratase
ISU55_RS12355	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ISU55_RS12355	COG0140	phosphoribosyl-ATP diphosphatase activity
ISU55_RS12365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU55_RS12370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ISU55_RS12385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ISU55_RS12390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS12395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS12400	COG1120	ATPase activity
ISU55_RS12415	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ISU55_RS12420	COG0076	glutamate decarboxylase activity
ISU55_RS12425	COG4114	ferric iron reductase
ISU55_RS12430	COG1253	flavin adenine dinucleotide binding
ISU55_RS12435	COG2982	Protein involved in outer membrane biogenesis
ISU55_RS12450	COG0489	protein tyrosine kinase activity
ISU55_RS12480	COG2814	Major facilitator Superfamily
ISU55_RS12490	COG1346	cytolysis
ISU55_RS12505	COG2949	membrane
ISU55_RS12510	COG4211	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS12525	COG2311	Membrane
ISU55_RS12535	COG0477	Major facilitator Superfamily
ISU55_RS12540	COG0583	DNA-binding transcription factor activity
ISU55_RS12570	COG1136	(ABC) transporter
ISU55_RS12580	COG0303	'Molybdopterin
ISU55_RS12590	COG3328	transposase activity
ISU55_RS12600	COG0488	(ABC) transporter
ISU55_RS12730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ISU55_RS12735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ISU55_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS12750	COG1024	Enoyl-CoA hydratase
ISU55_RS12760	COG3425	synthase
ISU55_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS12770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ISU55_RS12775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ISU55_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS12810	COG2920	part of a sulfur-relay system
ISU55_RS12830	COG1832	CoA-binding protein
ISU55_RS12845	COG0210	DNA helicase
ISU55_RS12850	COG3304	Inner membrane component domain
ISU55_RS12855	COG1289	transmembrane transporter activity
ISU55_RS12860	COG3070	regulator of competence-specific genes
ISU55_RS12885	COG1067	ATP-dependent peptidase activity
ISU55_RS12925	COG3130	regulation of translation
ISU55_RS12930	COG3009	Protein conserved in bacteria
ISU55_RS12935	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ISU55_RS12935	COG3008	intermembrane lipid transfer
ISU55_RS12940	COG2995	paraquat-inducible protein a
ISU55_RS12945	COG0488	(ABC) transporter
ISU55_RS12955	COG3217	Mosc domain protein beta barrel domain protein
ISU55_RS12955	COG0633	Ferredoxin
ISU55_RS12970	COG0308	aminopeptidase N
ISU55_RS12990	COG1448	Aminotransferase
ISU55_RS13000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU55_RS13005	COG3108	Peptidase M15
ISU55_RS13010	COG2989	Protein conserved in bacteria
ISU55_RS13035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ISU55_RS13040	COG3173	Aminoglycoside phosphotransferase
ISU55_RS13055	COG1278	Cold shock
ISU55_RS13060	COG5383	Protein conserved in bacteria
ISU55_RS13075	COG0658	competence protein
ISU55_RS13075	COG2333	competence protein COMEC
ISU55_RS13085	COG0539	negative regulation of cytoplasmic translation
ISU55_RS13110	COG5295	Hep Hag repeat protein
ISU55_RS13110	COG5295	Hep Hag repeat protein
ISU55_RS13115	COG0252	asparaginase activity
ISU55_RS13120	COG1944	ATP diphosphatase activity
ISU55_RS13125	COG2116	formate transmembrane transporter activity
ISU55_RS13130	COG1882	Formate acetyltransferase
ISU55_RS13140	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ISU55_RS13170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ISU55_RS13180	COG1674	ftsk spoiiie
ISU55_RS13180	COG3107	peptidoglycan biosynthetic process
ISU55_RS13190	COG0492	ferredoxin-NADP+ reductase activity
ISU55_RS13200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ISU55_RS13210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ISU55_RS13220	COG0542	response to heat
ISU55_RS13230	COG1278	Cold shock
ISU55_RS13240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU55_RS13245	COG2990	Protein conserved in bacteria
ISU55_RS13250	COG3593	DNA synthesis involved in DNA repair
ISU55_RS13255	COG2431	L-lysine efflux transmembrane transporter activity
ISU55_RS13265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU55_RS13270	COG0028	Belongs to the TPP enzyme family
ISU55_RS13280	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ISU55_RS13285	COG0702	epimerase
ISU55_RS13290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ISU55_RS13300	COG1605	Chorismate mutase
ISU55_RS13305	COG1126	abc transporter atp-binding protein
ISU55_RS13310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS13315	COG4215	(ABC) transporter
ISU55_RS13320	COG4160	amino acid transport
ISU55_RS13345	COG1120	ATPase activity
ISU55_RS13350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS13355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS13380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS13395	COG1177	transmembrane transport
ISU55_RS13400	COG1176	ABC-type spermidine putrescine transport system, permease component I
ISU55_RS13405	COG3842	ATPase activity
ISU55_RS13410	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ISU55_RS13440	COG0671	phosphoesterase, PA-phosphatase related
ISU55_RS13450	COG1349	DNA-binding transcription factor activity
ISU55_RS13455	COG0814	amino acid
ISU55_RS13460	COG1686	Belongs to the peptidase S11 family
ISU55_RS13465	COG2011	ABC-type metal ion transport system permease component
ISU55_RS13490	COG0625	glutathione transferase activity
ISU55_RS13495	COG4771	TonB-dependent receptor
ISU55_RS13505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ISU55_RS13515	COG0833	amino acid
ISU55_RS13520	COG0583	DNA-binding transcription factor activity
ISU55_RS13525	COG2855	membrane
ISU55_RS13535	COG3188	usher protein
ISU55_RS13540	COG3121	Chaperone
ISU55_RS13555	COG3710	Transcriptional regulator
ISU55_RS13560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU55_RS13560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU55_RS13560	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ISU55_RS13565	COG1105	Belongs to the carbohydrate kinase PfkB family
ISU55_RS13575	COG0494	nUDIX hydrolase
ISU55_RS13585	COG1129	ABC transporter
ISU55_RS13620	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS13645	COG0246	Mannitol dehydrogenase
ISU55_RS13650	COG2186	Transcriptional regulator
ISU55_RS13655	COG0523	cobalamin synthesis protein
ISU55_RS13660	COG0671	phosphoesterase, PA-phosphatase related
ISU55_RS13665	COG0791	NLP P60 protein
ISU55_RS13670	COG2200	EAL domain
ISU55_RS13675	COG4166	transmembrane transport
ISU55_RS13680	COG4174	ABC transporter (Permease)
ISU55_RS13685	COG4239	(ABC) transporter, permease
ISU55_RS13690	COG4172	Belongs to the ABC transporter superfamily
ISU55_RS13700	COG2814	Major facilitator Superfamily
ISU55_RS13705	COG1187	pseudouridine synthase activity
ISU55_RS13710	COG1061	Type III restriction enzyme res subunit
ISU55_RS13730	COG3082	Protein of unknown function (DUF1414)
ISU55_RS13735	COG3083	sulfuric ester hydrolase activity
ISU55_RS13750	COG3157	Type VI secretion system effector, Hcp
ISU55_RS13770	COG2723	6-phospho-beta-galactosidase activity
ISU55_RS13775	COG1737	Transcriptional regulator
ISU55_RS13795	COG3299	homolog of phage Mu protein gp47
ISU55_RS13835	COG4386	tail sheath protein
ISU55_RS13855	COG3622	Belongs to the hyi family
ISU55_RS13860	COG1349	DNA-binding transcription factor activity
ISU55_RS13870	COG3395	kinase activity
ISU55_RS13910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ISU55_RS13935	COG2223	nitrite transmembrane transporter activity
ISU55_RS13940	COG2198	Histidine kinase
ISU55_RS13940	COG0642	Histidine kinase
ISU55_RS13945	COG0642	Histidine kinase
ISU55_RS13945	COG2198	Histidine kinase
ISU55_RS13955	COG2205	protein histidine kinase activity
ISU55_RS13955	COG0784	Response regulator, receiver
ISU55_RS13980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ISU55_RS13995	COG0814	amino acid
ISU55_RS14020	COG0697	spore germination
ISU55_RS14030	COG1982	Orn Lys Arg decarboxylase major
ISU55_RS14035	COG0531	amino acid
ISU55_RS14040	COG1174	glycine betaine transport
ISU55_RS14045	COG1125	glycine betaine transport
ISU55_RS14050	COG1174	glycine betaine transport
ISU55_RS14060	COG2897	thiosulfate sulfurtransferase activity
ISU55_RS14080	COG1122	ATPase activity
ISU55_RS14100	COG4807	Protein conserved in bacteria
ISU55_RS14115	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ISU55_RS14125	COG2261	transglycosylase associated protein
ISU55_RS14145	COG0277	FAD linked oxidase domain protein
ISU55_RS14150	COG1686	Belongs to the peptidase S11 family
ISU55_RS14160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ISU55_RS14185	COG3328	transposase activity
ISU55_RS14220	COG0513	Belongs to the DEAD box helicase family
ISU55_RS14225	COG1309	transcriptional regulator
ISU55_RS14235	COG1131	(ABC) transporter
ISU55_RS14240	COG0842	Transport permease protein
ISU55_RS14245	COG0842	Transport permease protein
ISU55_RS14265	COG1902	pentaerythritol trinitrate reductase activity
ISU55_RS14300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ISU55_RS14310	COG0583	DNA-binding transcription factor activity
ISU55_RS14315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ISU55_RS14340	COG0670	Belongs to the BI1 family
ISU55_RS14345	COG0314	molybdopterin synthase activity
ISU55_RS14350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ISU55_RS14360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ISU55_RS14365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ISU55_RS14370	COG4628	conserved protein (DUF2132)
ISU55_RS14380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ISU55_RS14390	COG2226	methyltransferase
ISU55_RS14415	COG0561	phosphatase activity
ISU55_RS14425	COG4149	molybdate abc transporter
ISU55_RS14430	COG0725	ABC transporter, periplasmic molybdate-binding protein
ISU55_RS14440	COG2005	Transcriptional regulator
ISU55_RS14440	COG3585	molybdate ion transport
ISU55_RS14445	COG1119	ATPase activity
ISU55_RS14455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ISU55_RS14460	COG1085	galactose-1-phosphate uridylyltransferase
ISU55_RS14475	COG2017	converts alpha-aldose to the beta-anomer
ISU55_RS14490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ISU55_RS14495	COG1230	cation diffusion facilitator family transporter
ISU55_RS14525	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ISU55_RS14530	COG2885	chlorophyll binding
ISU55_RS14540	COG3064	Membrane
ISU55_RS14540	COG3064	Membrane
ISU55_RS14545	COG0848	biopolymer transport protein
ISU55_RS14550	COG0811	peptide transport
ISU55_RS14555	COG0824	Thioesterase
ISU55_RS14560	COG3790	cyd operon protein YbgE
ISU55_RS14565	COG4890	Cyd operon protein YbgT
ISU55_RS14570	COG1294	oxidase, subunit
ISU55_RS14575	COG1271	oxidase subunit
ISU55_RS14580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ISU55_RS14590	COG0508	dehydrogenase complex catalyzes the overall conversion of
ISU55_RS14595	COG0567	Dehydrogenase, E1 component
ISU55_RS14605	COG1053	succinate dehydrogenase
ISU55_RS14610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ISU55_RS14615	COG2009	succinate dehydrogenase
ISU55_RS14630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ISU55_RS14635	COG0497	DNA recombination
ISU55_RS14640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ISU55_RS14650	COG2867	negative regulation of translational initiation
ISU55_RS14670	COG0582	viral genome integration into host DNA
ISU55_RS14720	COG3657	addiction module killer protein
ISU55_RS14745	COG1953	Uracil, thiamine, allantoin
ISU55_RS14765	COG2226	methyltransferase
ISU55_RS14770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ISU55_RS14775	COG1388	LysM domain
ISU55_RS14775	COG0741	lytic transglycosylase activity
ISU55_RS14790	COG0656	L-ascorbic acid biosynthetic process
ISU55_RS14820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ISU55_RS14830	COG2011	ABC-type metal ion transport system permease component
ISU55_RS14835	COG1464	Belongs to the NlpA lipoprotein family
ISU55_RS14845	COG1720	tRNA m6t6A37 methyltransferase activity
ISU55_RS14855	COG3015	lipoprotein NlpE involved in copper resistance
ISU55_RS14865	COG4681	YaeQ
ISU55_RS14875	COG4568	rho-dependent transcription termination
ISU55_RS14885	COG0037	tRNA processing
ISU55_RS14890	COG0346	lactoylglutathione lyase activity
ISU55_RS14900	COG0587	DNA-directed DNA polymerase activity
ISU55_RS14925	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ISU55_RS14940	COG0750	zinc metalloprotease
ISU55_RS14945	COG0575	Belongs to the CDS family
ISU55_RS15005	COG0564	pseudouridine synthase activity
ISU55_RS15010	COG3098	single-species biofilm formation
ISU55_RS15030	COG1611	Belongs to the LOG family
ISU55_RS15045	COG2363	Small membrane protein
ISU55_RS15050	COG0583	DNA-binding transcription factor activity
ISU55_RS15060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ISU55_RS15065	COG2166	iron-sulfur cluster assembly
ISU55_RS15070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ISU55_RS15075	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ISU55_RS15090	COG0860	N-Acetylmuramoyl-L-alanine amidase
ISU55_RS15100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ISU55_RS15105	COG1074	ATP-dependent DNA helicase activity
ISU55_RS15130	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ISU55_RS15180	COG0667	Aldo Keto reductase
ISU55_RS15210	COG1609	Transcriptional regulator
ISU55_RS15220	COG0583	DNA-binding transcription factor activity
ISU55_RS15225	COG2814	Major facilitator Superfamily
ISU55_RS15230	COG0583	DNA-binding transcription factor activity
ISU55_RS15245	COG0840	transmembrane signaling receptor activity
ISU55_RS15290	COG2165	general secretion pathway protein
ISU55_RS15310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ISU55_RS15330	COG0288	reversible hydration of carbon dioxide
ISU55_RS15370	COG3119	arylsulfatase activity
ISU55_RS15375	COG1349	DNA-binding transcription factor activity
ISU55_RS15385	COG2222	sugar isomerase
ISU55_RS15390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU55_RS15395	COG3715	PTS system
ISU55_RS15400	COG3716	PTS system mannose fructose sorbose family IID component
ISU55_RS15405	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS15415	COG1028	Short-chain dehydrogenase reductase Sdr
ISU55_RS15425	COG0641	radical SAM
ISU55_RS15430	COG3119	arylsulfatase activity
ISU55_RS15455	COG2271	Major facilitator Superfamily
ISU55_RS15475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ISU55_RS15475	COG1263	PTS System
ISU55_RS15480	COG1874	Beta-galactosidase
ISU55_RS15485	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ISU55_RS15490	COG3833	ABC-type maltose transport systems, permease component
ISU55_RS15495	COG1175	transmembrane transport
ISU55_RS15500	COG2182	Extracellular solute-binding protein
ISU55_RS15510	COG1129	ABC transporter
ISU55_RS15515	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS15520	COG1879	ABC-type sugar transport system periplasmic component
ISU55_RS15530	COG0791	NLP P60 protein
ISU55_RS15535	COG1695	Transcriptional regulator
ISU55_RS15625	COG2944	sequence-specific DNA binding
ISU55_RS15650	COG0582	viral genome integration into host DNA
ISU55_RS15670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ISU55_RS15675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU55_RS15680	COG4974	Belongs to the 'phage' integrase family
ISU55_RS15685	COG0716	FMN binding
ISU55_RS15690	COG4452	Inner membrane protein CreD
ISU55_RS15695	COG2205	protein histidine kinase activity
ISU55_RS15700	COG0745	RESPONSE REGULATOR receiver
ISU55_RS15725	COG1272	protein, Hemolysin III
ISU55_RS15770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU55_RS15775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ISU55_RS15780	COG0006	proline dipeptidase activity
ISU55_RS15800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ISU55_RS15810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ISU55_RS15845	COG0191	fructose-bisphosphate aldolase activity
ISU55_RS15880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ISU55_RS15885	COG0501	Belongs to the peptidase M48B family
ISU55_RS15900	COG1166	arginine decarboxylase activity
ISU55_RS15915	COG2356	endonuclease I
ISU55_RS15920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ISU55_RS15925	COG0189	ligase activity
ISU55_RS15940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ISU55_RS15950	COG2805	Type II/IV secretion system protein
ISU55_RS15955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ISU55_RS15960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ISU55_RS15965	COG0762	integral membrane protein
ISU55_RS15975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ISU55_RS15980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU55_RS15985	COG3064	Membrane
ISU55_RS15985	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ISU55_RS15985	COG1073	alpha beta
ISU55_RS16010	COG3171	Protein conserved in bacteria
ISU55_RS16020	COG1194	a g-specific adenine glycosylase
ISU55_RS16040	COG4774	siderophore transport
ISU55_RS16045	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS16050	COG1129	ABC transporter
ISU55_RS16055	COG1879	ABC-type sugar transport system periplasmic component
ISU55_RS16060	COG1982	Orn Lys Arg decarboxylase major
ISU55_RS16175	COG3916	Acyl-homoserine-lactone synthase
ISU55_RS16180	COG2771	luxR family
ISU55_RS16230	COG2211	Major facilitator Superfamily
ISU55_RS16240	COG5001	Diguanylate cyclase
ISU55_RS16250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU55_RS16295	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ISU55_RS16300	COG2195	Cleaves the N-terminal amino acid of tripeptides
ISU55_RS16305	COG4771	TonB-dependent receptor
ISU55_RS16325	COG3433	isochorismatase activity
ISU55_RS16325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU55_RS16325	COG2226	methyltransferase
ISU55_RS16335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ISU55_RS16335	COG2226	methyltransferase
ISU55_RS16335	COG3433	isochorismatase activity
ISU55_RS16360	COG2375	cellular response to nickel ion
ISU55_RS16360	COG1132	(ABC) transporter
ISU55_RS16365	COG1132	(ABC) transporter
ISU55_RS16380	COG2610	gluconate transmembrane transporter activity
ISU55_RS16395	COG3501	Rhs element vgr protein
ISU55_RS16420	COG0471	metal ion transport
ISU55_RS16445	COG3710	Transcriptional regulator
ISU55_RS16465	COG1256	bacterial-type flagellum assembly
ISU55_RS16475	COG1706	bacterial-type flagellum-dependent cell motility
ISU55_RS16485	COG4786	Flagellar basal body rod
ISU55_RS16490	COG4787	bacterial-type flagellum-dependent cell motility
ISU55_RS16495	COG1749	Flagellar hook protein flgE
ISU55_RS16500	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ISU55_RS16505	COG1558	bacterial-type flagellum-dependent cell motility
ISU55_RS16510	COG1815	bacterial-type flagellum-dependent cell motility
ISU55_RS16515	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
ISU55_RS16555	COG1677	Flagellar hook-basal body complex protein FliE
ISU55_RS16580	COG1987	bacterial-type flagellum assembly
ISU55_RS16585	COG1684	flagellar biosynthetic protein fliR
ISU55_RS16590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ISU55_RS16610	COG4592	Periplasmic binding protein
ISU55_RS16645	COG4964	Belongs to the GSP D family
ISU55_RS16650	COG4964	Belongs to the GSP D family
ISU55_RS16700	COG0848	biopolymer transport protein
ISU55_RS16705	COG0811	peptide transport
ISU55_RS16710	COG0626	cystathionine gamma-synthase activity
ISU55_RS16715	COG0586	Pfam SNARE associated Golgi protein
ISU55_RS16720	COG2207	Transcriptional regulator
ISU55_RS16725	COG1979	alcohol dehydrogenase
ISU55_RS16735	COG0656	L-ascorbic acid biosynthetic process
ISU55_RS16745	COG2132	Multicopper oxidase
ISU55_RS16755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ISU55_RS16770	COG0583	DNA-binding transcription factor activity
ISU55_RS16780	COG3150	esterase
ISU55_RS16785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ISU55_RS16790	COG3151	Protein conserved in bacteria
ISU55_RS16795	COG0494	nUDIX hydrolase
ISU55_RS16800	COG1538	Outer membrane efflux protein
ISU55_RS16810	COG0754	glutathionylspermidine amidase activity
ISU55_RS16815	COG3384	dioxygenase
ISU55_RS16835	COG0531	amino acid
ISU55_RS16850	COG3025	triphosphatase activity
ISU55_RS16855	COG4991	sh3 domain protein
ISU55_RS16870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ISU55_RS16885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ISU55_RS16890	COG0358	DNA primase activity
ISU55_RS16970	COG0251	oxidation-reduction process
ISU55_RS16990	COG0436	Aminotransferase
ISU55_RS17010	COG1289	transmembrane transporter activity
ISU55_RS17030	COG0395	ABC-type sugar transport system, permease component
ISU55_RS17040	COG2182	Extracellular solute-binding protein
ISU55_RS17045	COG1609	Transcriptional regulator
ISU55_RS17050	COG3459	Glycosyltransferase 36 associated
ISU55_RS17055	COG3842	ATPase activity
ISU55_RS17075	COG3210	domain, Protein
ISU55_RS17080	COG3210	domain, Protein
ISU55_RS17110	COG3210	domain, Protein
ISU55_RS17115	COG2831	hemolysin activation secretion protein
ISU55_RS17120	COG4245	von Willebrand factor, type A
ISU55_RS17135	COG4245	von Willebrand factor, type A
ISU55_RS17150	COG3247	response to pH
ISU55_RS17155	COG0446	pyridine nucleotide-disulphide oxidoreductase
ISU55_RS17155	COG1902	pentaerythritol trinitrate reductase activity
ISU55_RS17170	COG1451	nucleotide metabolic process
ISU55_RS17175	COG0673	inositol 2-dehydrogenase activity
ISU55_RS17195	COG2721	sulfolactate sulfo-lyase activity
ISU55_RS17215	COG2271	Major facilitator Superfamily
ISU55_RS17230	COG0586	Pfam SNARE associated Golgi protein
ISU55_RS17245	COG4575	ribosome binding
ISU55_RS17250	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ISU55_RS17260	COG2259	Doxx family
ISU55_RS17280	COG0494	nUDIX hydrolase
ISU55_RS17310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ISU55_RS17315	COG0849	cell division
ISU55_RS17320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ISU55_RS17340	COG0772	Belongs to the SEDS family
ISU55_RS17355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ISU55_RS17360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ISU55_RS17365	COG0768	penicillin binding
ISU55_RS17370	COG3116	cell division
ISU55_RS17395	COG1609	Transcriptional regulator
ISU55_RS17410	COG0028	Belongs to the TPP enzyme family
ISU55_RS17415	COG1022	Amp-dependent synthetase and ligase
ISU55_RS17440	COG0473	3-isopropylmalate dehydrogenase activity
ISU55_RS17455	COG2814	Major facilitator Superfamily
ISU55_RS17465	COG4143	(ABC) transporter
ISU55_RS17470	COG1178	ABC-type Fe3 transport system permease component
ISU55_RS17475	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ISU55_RS17480	COG0586	Pfam SNARE associated Golgi protein
ISU55_RS17485	COG0417	DNA replication proofreading
ISU55_RS17505	COG2885	chlorophyll binding
ISU55_RS17505	COG3047	cAMP biosynthetic process
ISU55_RS17590	COG0564	pseudouridine synthase activity
ISU55_RS17595	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ISU55_RS17645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ISU55_RS17655	COG2966	Psort location CytoplasmicMembrane, score
ISU55_RS17660	COG1280	lysine exporter protein (LysE YggA)
ISU55_RS17665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISU55_RS17690	COG1047	Peptidyl-prolyl cis-trans
ISU55_RS17705	COG0196	riboflavin kinase activity
ISU55_RS17715	COG0583	DNA-binding transcription factor activity
ISU55_RS17735	COG1584	GPR1 FUN34 yaaH family protein
ISU55_RS17750	COG0521	Mo-molybdopterin cofactor biosynthetic process
ISU55_RS17790	COG0745	RESPONSE REGULATOR receiver
ISU55_RS17795	COG3045	CreA protein
ISU55_RS17800	COG3708	Transcriptional regulator
ISU55_RS17800	COG2207	Transcriptional regulator
ISU55_RS17815	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ISU55_RS17820	COG0741	lytic transglycosylase activity
ISU55_RS17835	COG2199	diguanylate cyclase activity
ISU55_RS17840	COG2885	chlorophyll binding
ISU55_RS17865	COG0560	Phosphoserine phosphatase
ISU55_RS17870	COG3726	membrane protein affecting hemolysin expression
ISU55_RS17895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ISU55_RS17900	COG0084	hydrolase, TatD family'
ISU55_RS17905	COG4667	esterase of the alpha-beta hydrolase superfamily
ISU55_RS17915	COG2823	Periplasmic or secreted lipoprotein
ISU55_RS17925	COG0456	acetyltransferase
ISU55_RS17930	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ISU55_RS17970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ISU55_RS17975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ISU55_RS17990	COG0859	PFAM glycosyl transferase family 9
ISU55_RS17995	COG1070	Carbohydrate kinase
ISU55_RS18045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS18045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ISU55_RS18045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ISU55_RS18050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU55_RS18055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU55_RS18060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ISU55_RS18065	COG2207	Transcriptional regulator
ISU55_RS18075	COG4269	membrane
ISU55_RS18130	COG1401	restriction endodeoxyribonuclease activity
ISU55_RS18155	COG1011	Hydrolase
ISU55_RS18165	COG0174	glutamine synthetase
ISU55_RS18170	COG3852	Histidine kinase
ISU55_RS18180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ISU55_RS18205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU55_RS18205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ISU55_RS18210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ISU55_RS18215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ISU55_RS18220	COG3084	Protein conserved in bacteria
ISU55_RS18230	COG1763	Mo-molybdopterin cofactor biosynthetic process
ISU55_RS18235	COG3328	transposase activity
ISU55_RS18295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU55_RS18295	COG0678	peroxiredoxin activity
ISU55_RS18300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU55_RS18325	COG1629	transport
ISU55_RS18340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ISU55_RS18375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ISU55_RS18380	COG0058	SHG alpha-glucan phosphorylase activity
ISU55_RS18405	COG3275	phosphorelay sensor kinase activity
ISU55_RS18440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ISU55_RS18445	COG2095	MarC family integral membrane protein
ISU55_RS18460	COG3265	gluconokinase activity
ISU55_RS18465	COG2610	gluconate transmembrane transporter activity
ISU55_RS18470	COG1609	Transcriptional regulator
ISU55_RS18475	COG1741	Belongs to the pirin family
ISU55_RS18495	COG0191	fructose-bisphosphate aldolase activity
ISU55_RS18510	COG1172	Belongs to the binding-protein-dependent transport system permease family
ISU55_RS18525	COG2081	HI0933 family
ISU55_RS18530	COG0306	phosphate transporter
ISU55_RS18545	COG0589	response to stress
ISU55_RS18565	COG0339	signal peptide processing
ISU55_RS18570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ISU55_RS18575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ISU55_RS18580	COG3835	regulator
ISU55_RS18590	COG2610	gluconate transmembrane transporter activity
ISU55_RS18595	COG1929	Belongs to the glycerate kinase type-1 family
ISU55_RS18620	COG1295	ribonuclease BN
ISU55_RS18625	COG2134	cdp-diacylglycerol pyrophosphatase
ISU55_RS18630	COG2982	Protein involved in outer membrane biogenesis
ISU55_RS18635	COG2200	EAL domain
ISU55_RS18640	COG1942	4-Oxalocrotonate Tautomerase
ISU55_RS18645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU55_RS18650	COG0612	Peptidase, M16
ISU55_RS18670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ISU55_RS18675	COG2199	diguanylate cyclase activity
ISU55_RS18675	COG2200	EAL domain
ISU55_RS18680	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ISU55_RS18685	COG4608	Belongs to the ABC transporter superfamily
ISU55_RS18690	COG0444	Belongs to the ABC transporter superfamily
ISU55_RS18695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ISU55_RS18700	COG0601	transmembrane transport
ISU55_RS18705	COG0747	negative chemotaxis
ISU55_RS18710	COG2831	hemolysin activation secretion protein
ISU55_RS18725	COG2271	Major facilitator Superfamily
ISU55_RS18745	COG0456	acetyltransferase
ISU55_RS18750	COG2982	Protein involved in outer membrane biogenesis
ISU55_RS18755	COG2233	PERMEase
ISU55_RS18760	COG0786	glutamate:sodium symporter activity
ISU55_RS18770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ISU55_RS18775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ISU55_RS18780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ISU55_RS18800	COG2860	membrane
ISU55_RS18805	COG1561	YicC-like family, N-terminal region
ISU55_RS18830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ISU55_RS18865	COG1519	Transferase
ISU55_RS18870	COG0859	PFAM glycosyl transferase family 9
ISU55_RS18875	COG0859	PFAM glycosyl transferase family 9
ISU55_RS18885	COG0156	8-amino-7-oxononanoate synthase activity
ISU55_RS18900	COG4942	peptidase
ISU55_RS18910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ISU55_RS18915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ISU55_RS18930	COG1045	serine acetyltransferase
ISU55_RS18935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ISU55_RS18940	COG2169	Transcriptional regulator
ISU55_RS18940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ISU55_RS18945	COG2205	protein histidine kinase activity
ISU55_RS18950	COG0745	RESPONSE REGULATOR receiver
ISU55_RS18955	COG3678	ATP-independent chaperone mediated protein folding
ISU55_RS18980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ISU55_RS18990	COG0471	metal ion transport
ISU55_RS18995	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ISU55_RS19010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ISU55_RS19015	COG0583	DNA-binding transcription factor activity
ISU55_RS19030	COG3152	Membrane
ISU55_RS19040	COG1494	fructose-1,6-bisphosphatase
ISU55_RS19045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ISU55_RS19050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ISU55_RS19090	COG1575	Belongs to the MenA family. Type 1 subfamily
ISU55_RS19105	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ISU55_RS19110	COG1609	Transcriptional regulator
ISU55_RS19115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ISU55_RS19125	COG4682	membrane
ISU55_RS19140	COG0460	homoserine dehydrogenase
ISU55_RS19140	COG0527	aspartate kinase activity
ISU55_RS19155	COG1349	DNA-binding transcription factor activity
ISU55_RS19175	COG0058	SHG alpha-glucan phosphorylase activity
ISU55_RS19180	COG0058	SHG alpha-glucan phosphorylase activity
ISU55_RS19185	COG1640	4-alpha-glucanotransferase
ISU55_RS19220	COG1918	ferrous iron import across plasma membrane
ISU55_RS19225	COG2183	response to ionizing radiation
ISU55_RS19230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ISU55_RS19255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ISU55_RS19260	COG1011	Hydrolase
ISU55_RS19270	COG0494	nUDIX hydrolase
ISU55_RS19275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ISU55_RS19300	COG4796	Type ii and iii secretion system protein
ISU55_RS19325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ISU55_RS19330	COG0546	phosphoglycolate phosphatase activity
ISU55_RS19335	COG0180	Tryptophanyl-tRNA synthetase
ISU55_RS19355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ISU55_RS19360	COG0402	S-adenosylhomocysteine deaminase activity
ISU55_RS19400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ISU55_RS19405	COG0433	COG0433 Predicted ATPase
ISU55_RS19420	COG1289	transmembrane transporter activity
ISU55_RS19430	COG1765	OsmC-like protein
ISU55_RS19440	COG3954	Phosphoribulokinase
ISU55_RS19450	COG0429	hydrolase of the alpha beta-hydrolase fold
ISU55_RS19460	COG4521	taurine ABC transporter
ISU55_RS19470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ISU55_RS19475	COG2175	clavaminate synthase activity
ISU55_RS19485	COG1216	Glycosyl transferase, family 2
ISU55_RS19505	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ISU55_RS19510	COG1047	Peptidyl-prolyl cis-trans
ISU55_RS19520	COG0545	Peptidyl-prolyl cis-trans isomerase
ISU55_RS19525	COG2964	Protein conserved in bacteria
ISU55_RS19545	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ISU55_RS19550	COG0049	tRNA binding
ISU55_RS19580	COG0051	transcription antitermination factor activity, RNA binding
ISU55_RS19595	COG0089	rRNA binding
ISU55_RS19605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ISU55_RS19615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ISU55_RS19620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ISU55_RS19630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ISU55_RS19635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ISU55_RS19675	COG1841	ribosomal large subunit assembly
ISU55_RS19685	COG0201	protein transport
ISU55_RS19690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ISU55_RS19705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ISU55_RS19720	COG0789	Transcriptional regulator
ISU55_RS19725	COG3036	rescue of stalled ribosome
ISU55_RS19755	COG0758	DNA mediated transformation
ISU55_RS19765	COG0551	DNA topoisomerase type I activity
ISU55_RS19780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ISU55_RS19800	COG2197	response regulator
ISU55_RS19805	COG2194	sulfuric ester hydrolase activity
ISU55_RS19820	COG2986	histidine ammonia-lyase
ISU55_RS19850	COG4607	ABC-type enterochelin transport system periplasmic component
ISU55_RS19860	COG4605	iron ion homeostasis
ISU55_RS19865	COG4604	ABC transporter, ATP-binding protein
ISU55_RS19910	COG0582	viral genome integration into host DNA
ISU55_RS19920	COG1609	Transcriptional regulator
ISU55_RS19920	COG2207	Transcriptional regulator
ISU55_RS19925	COG4214	carbohydrate transport
ISU55_RS19935	COG4213	ABC transporter substrate-binding protein
ISU55_RS19945	COG1070	Carbohydrate kinase
ISU55_RS19955	COG3121	Chaperone
ISU55_RS19970	COG3274	enterobacterial common antigen metabolic process
ISU55_RS20055	COG1175	transmembrane transport
ISU55_RS20060	COG3833	ABC-type maltose transport systems, permease component
ISU55_RS20075	COG0527	aspartate kinase activity
ISU55_RS20105	COG2224	Isocitrate lyase
ISU55_RS20110	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ISU55_RS20150	COG2186	Transcriptional regulator
ISU55_RS20155	COG0477	Major facilitator Superfamily
ISU55_RS20170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ISU55_RS20200	COG1522	sequence-specific DNA binding
ISU55_RS20205	COG0716	FMN binding
ISU55_RS20220	COG3312	ion transport
ISU55_RS20275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ISU55_RS20280	COG0573	inorganic phosphate transmembrane transporter activity
ISU55_RS20285	COG0581	inorganic phosphate transmembrane transporter activity
ISU55_RS20295	COG0704	Plays a role in the regulation of phosphate uptake
ISU55_RS20305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ISU55_RS20310	COG0765	amino acid transport
ISU55_RS20315	COG0765	amino acid transport
ISU55_RS20320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ISU55_RS20330	COG2252	PERMEase
ISU55_RS20360	COG0706	membrane insertase activity
ISU55_RS20375	COG0230	Belongs to the bacterial ribosomal protein bL34 family