locus-tag class description AK38_RS00030 ENOG4108D1K outer membrane usher protein AK38_RS00035 ENOG4108UIF Chaperone AK38_RS00040 ENOG4106PHM regulatory protein AK38_RS00055 ENOG4105EQR Transposase IS116 IS110 IS902 AK38_RS00120 ENOG4106RMF ParB family AK38_RS00145 ENOG41073YN Protein of unknown function (DUF1380) AK38_RS00165 ENOG4105FEQ ParB domain protein nuclease AK38_RS00180 ENOG4106J5W DNA polymerase III (alpha subunit) AK38_RS00210 ENOG4105C2M dna polymerase I AK38_RS00265 ENOG4106JVB Replication Protein AK38_RS00280 ENOG4105D2X ABC transporter substrate-binding protein AK38_RS00365 ENOG4105CB5 ATP-dependent DNA helicase recG AK38_RS00370 ENOG4105FA0 parb-like partition protein AK38_RS00375 ENOG4105FA0 parb-like partition protein AK38_RS00470 ENOG4108NYK Tape measure protein AK38_RS00505 ENOG4108X9F tail fiber protein AK38_RS00505 ENOG4108X9F tail fiber protein AK38_RS00515 ENOG4105UZW Tail fiber assembly protein AK38_RS00625 ENOG4108C33 Resolvase AK38_RS00630 ENOG4105D13 transposase AK38_RS00680 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) AK38_RS00690 ENOG4106CQM replication AK38_RS00995 ENOG4105CJN penicillin-binding protein AK38_RS01000 ENOG4105CNI cell division protein FtsW AK38_RS01005 ENOG4105K6T rare lipoprotein A AK38_RS01010 ENOG4105DZ1 carboxypeptidase AK38_RS01030 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) AK38_RS01040 ENOG4107Z6W Protein CrcB homolog AK38_RS01055 ENOG4108N8T regulatoR AK38_RS01080 ENOG4108JJ7 ABC transporter AK38_RS01090 ENOG4105DH8 myo-inositol catabolism AK38_RS01100 ENOG4105EDK PfkB domain protein AK38_RS01105 ENOG4105CK5 oxidoreductase AK38_RS01110 ENOG4105CNN ABC, transporter AK38_RS01115 ENOG4105C2J ABC transporter AK38_RS01120 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_RS01130 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) AK38_RS01135 ENOG4105C26 Dehydrogenase AK38_RS01150 ENOG4105DN3 alpha-2-macroglobulin domain protein AK38_RS01155 ENOG4108JQB penicillin-binding protein 1C AK38_RS01175 ENOG4107P2S Transcriptional regulator AK38_RS01180 ENOG4105C6K Malic enzyme AK38_RS01205 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 AK38_RS01210 ENOG4107QWE )-transporter AK38_RS01225 ENOG4105CHM Aminotransferase AK38_RS01235 ENOG4107NQ8 LysR family Transcriptional regulator AK38_RS01245 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) AK38_RS01255 ENOG4105GKE subunit e AK38_RS01260 ENOG4107QIZ NADH dehydrogenase AK38_RS01265 ENOG4108IEH NADH dehydrogenase subunit g AK38_RS01280 ENOG4107UFS subunit j AK38_RS01290 ENOG4105D65 subunit l AK38_RS01295 ENOG4105C8S subunit m AK38_RS01310 ENOG4108R66 Conserved Protein AK38_RS01315 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AK38_RS01320 ENOG4105CHR reductase AK38_RS01325 ENOG4105F32 YngK protein AK38_RS01330 ENOG4105K2J Transcriptional regulator AK38_RS01340 ENOG4105C5I Dehydrogenase AK38_RS01355 ENOG4105C01 Dihydroxy-acid dehydratase AK38_RS01370 ENOG4105TNS Conserved Protein AK38_RS01380 ENOG4105E4F Isochorismate synthase AK38_RS01395 ENOG4108IPT Naphthoate synthase AK38_RS01405 ENOG4105CEY Amp-dependent synthetase and ligase AK38_RS01410 ENOG4108MTB glycosyl transferase family AK38_RS01415 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction AK38_RS01435 ENOG4107SDU Methyl-accepting chemotaxis AK38_RS01440 ENOG4105CDA abc transporter atp-binding protein AK38_RS01445 ENOG4105E5Q amino acid AbC transporter AK38_RS01450 ENOG4107R0W ABC transporter AK38_RS01480 ENOG4108T1M outer membrane protein x AK38_RS01500 ENOG4105CPQ Dehydrogenase AK38_RS01505 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_RS01510 ENOG4105C2J ABC transporter AK38_RS01515 ENOG4105CNN ABC, transporter AK38_RS01520 ENOG4105FKQ transcriptional regulator AK38_RS01525 ENOG4105EJC lysr family transcriptional regulator AK38_RS01530 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AK38_RS01535 ENOG4105C94 Transporter AK38_RS01540 ENOG4105DVW rieske (2Fe-2S) AK38_RS01545 ENOG4105E3J oxidoreductase AK38_RS01550 ENOG4105D5K Hemolysin activator protein AK38_RS01555 ENOG4105CKT filamentous hemagglutinin AK38_RS01575 ENOG4105CKT filamentous hemagglutinin AK38_RS01595 ENOG4105CKT filamentous hemagglutinin AK38_RS01605 ENOG4108IJ9 (ABC) transporter AK38_RS01615 ENOG4105ETE Transcriptional regulator (LacI family AK38_RS01630 ENOG4105DRS transport system, permease AK38_RS01635 ENOG4105HY2 Glycosidase related protein AK38_RS01655 ENOG4105CUY Mechanosensitive ion channel AK38_RS01660 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) AK38_RS01665 ENOG4107IIZ CRISPR-associated helicase, Cas3 AK38_RS01670 ENOG4105ENG CRISPR-associated protein, Csy1 family AK38_RS01675 ENOG4105DZX CRISPR-associated protein, Csy2 family AK38_RS01680 ENOG4105M6W Crispr-associated protein, Csy3 family AK38_RS01685 ENOG4108Y1S CRISPR-associated protein, Csy4 family AK38_RS01690 ENOG4105CPC Aldo Keto reductase AK38_RS01700 ENOG4105C54 Major Facilitator superfamily AK38_RS01710 ENOG4105ETT transcriptional Regulator, LysR family AK38_RS01715 ENOG4105VJY transcriptional regulator AK38_RS01720 ENOG4107YC3 synthase AK38_RS01750 ENOG4105DSF transport protein AK38_RS01770 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 AK38_RS01775 ENOG4107PN8 YfeABCD locus regulator AK38_RS01790 ENOG4105CC5 ABC transporter AK38_RS01795 ENOG4105CC5 ABC transporter AK38_RS01800 ENOG4105DIK (ABC) transporter AK38_RS01805 ENOG4105DSE periplasmic solute binding protein AK38_RS01830 ENOG41087WU AK38_RS01860 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) AK38_RS01865 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) AK38_RS01880 ENOG4108V06 Glutathione peroxidase AK38_RS01925 ENOG4108QBX (LipO)protein AK38_RS01940 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_RS01950 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) AK38_RS01960 ENOG4105IPI Membrane AK38_RS01965 ENOG4105CQB FAD linked oxidase domain protein AK38_RS01970 ENOG4105KA0 thioesterase Superfamily protein AK38_RS01980 ENOG4108Z4V iron-sulfur cluster assembly AK38_RS01985 ENOG4105DIW FeS assembly protein SUFB AK38_RS01990 ENOG4105C3K feS assembly ATPase SufC AK38_RS01995 ENOG4105JRK feS assembly protein SufD AK38_RS02010 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein AK38_RS02050 ENOG4105CA9 Pyruvate kinase AK38_RS02070 ENOG4108R6K riboflavin synthase, subunit alpha AK38_RS02075 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase AK38_RS02080 ENOG4105CZQ inner membrane transport protein YdhC AK38_RS02085 ENOG4105F52 Transcriptional regulator AK38_RS02095 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AK38_RS02100 ENOG4105K4H Nlp p60 protein AK38_RS02110 ENOG4105M2J Glutaredoxin AK38_RS02115 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) AK38_RS02120 ENOG4108UYE Lactoylglutathione lyase AK38_RS02130 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AK38_RS02135 ENOG4108WUH Transcriptional regulator, TetR family AK38_RS02140 ENOG4105DIJ Phosphoethanolamine transferase AK38_RS02145 ENOG4105XZD Fe-S protein AK38_RS02150 ENOG4107RGM aldo keto reductase AK38_RS02160 ENOG4108XTF Outer Membrane Lipoprotein AK38_RS02170 ENOG410642K Lysozyme inhibitor AK38_RS02190 ENOG4108K3A Glutathione S-transferase AK38_RS02205 ENOG4108ZR5 Conserved Protein AK38_RS02210 ENOG41069YE inner membrane protein yohC AK38_RS02215 ENOG4105DUX Transporter AK38_RS02220 ENOG4105Q4T oxidoreductase AK38_RS02225 ENOG4108JQ2 peptide transport system atp-binding protein AK38_RS02230 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein AK38_RS02235 ENOG4108EU3 peptide transport system, permease AK38_RS02240 ENOG4108I5W peptide transport system, permease protein AK38_RS02245 ENOG4108HIY periplasmic AK38_RS02265 ENOG4105E51 psp operon transcriptional activator AK38_RS02270 ENOG41087YS Phage shock protein A AK38_RS02275 ENOG4105YYT phage shock protein B AK38_RS02280 ENOG4105FM1 phage shock protein C AK38_RS02290 ENOG4105CM6 amino acid regulated cytosolic protein AK38_RS02315 ENOG4108RS6 transposase AK38_RS02320 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) AK38_RS02325 ENOG4107S8C mandelate racemase muconate lactonizing AK38_RS02330 ENOG4105KXI murein peptide amidase A AK38_RS02335 ENOG4107QSI ABC, transporter AK38_RS02365 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) AK38_RS02375 ENOG4105KT7 mgtC SapB transporter AK38_RS02380 ENOG4105IKK cytoplasmic protein AK38_RS02385 ENOG41090X5 Heat shock protein hslJ AK38_RS02390 ENOG4105C5I Dehydrogenase AK38_RS02395 ENOG4107H52 Dicarboxylate transport AK38_RS02400 ENOG410689M (LipO)protein AK38_RS02405 ENOG4105WXT Conserved Protein AK38_RS02410 ENOG4105DEI Mannitol dehydrogenase AK38_RS02415 ENOG4105DKT Transcriptional regulator AK38_RS02425 ENOG4105CQ7 ATP-dependent helicase AK38_RS02440 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap AK38_RS02455 ENOG4105DS1 cytochrome b561 AK38_RS02490 ENOG4105CTD carboxy-peptidase AK38_RS02495 ENOG4105JJR Histidine kinase AK38_RS02500 ENOG4107EXC regulatoR AK38_RS02510 ENOG4105D5Q Arginine ornithine antiporter AK38_RS02515 ENOG4105C5D exported protein AK38_RS02525 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AK38_RS02530 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) AK38_RS02535 ENOG4105Q9Y Universal stress protein AK38_RS02540 ENOG4105DS0 Transcriptional regulator, Crp Fnr family AK38_RS02545 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AK38_RS02565 ENOG4105PAD Hydrolase AK38_RS02570 ENOG4105M71 acetolactate synthase 1 regulatory subunit AK38_RS02575 ENOG4105C7K acetolactate synthase AK38_RS02600 ENOG4105FYV Amp nucleosidase AK38_RS02605 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AK38_RS02625 ENOG41060NJ transcriptional regulator AK38_RS02695 ENOG4105CMQ Chloride channel AK38_RS02700 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) AK38_RS02705 ENOG4105DAG ROK family AK38_RS02710 ENOG4106NZI LysR family Transcriptional regulator AK38_RS02715 ENOG4105D94 Major Facilitator Superfamily AK38_RS02720 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) AK38_RS02725 ENOG4105C9Q fumarate hydratase class II AK38_RS02730 ENOG4105EIP mannose-6-phosphate isomerase AK38_RS02735 ENOG4106J39 exported protein AK38_RS02745 ENOG4105DHU Bile acid AK38_RS02750 ENOG4105D9R oxidoreductase AK38_RS02760 ENOG4105CNN ABC, transporter AK38_RS02765 ENOG4105C2J ABC transporter AK38_RS02770 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator AK38_RS02785 ENOG4108JJA ABC, transporter AK38_RS02790 ENOG4105C42 Type I secretion membrane fusion protein (HlyD AK38_RS02805 ENOG4108JJA ABC, transporter AK38_RS02810 ENOG4105M9B inner membrane protein ydgK AK38_RS02830 ENOG4105UEI Transcriptional Regulator AraC Family AK38_RS02835 ENOG4105D6A Electron transport complex AK38_RS02840 ENOG4108UQQ Electron transport complex AK38_RS02850 ENOG4105CSM endonuclease III AK38_RS02855 ENOG4105EXW epimerase dehydratase AK38_RS02860 ENOG4105CSP Major Facilitator Superfamily AK38_RS02870 ENOG4105D22 carbon starvation protein AK38_RS02875 ENOG4105VCD cytoplasmic protein AK38_RS02880 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) AK38_RS02890 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AK38_RS02900 ENOG4108ZJT translation initiation factor, Sui1 AK38_RS02915 ENOG4105CFV Tetratricopeptide repeat protein AK38_RS02920 ENOG4105Q4A inner membrane protein yciS AK38_RS02925 ENOG4105EYK Phosphatidylglycerophosphatase B AK38_RS02935 ENOG4107QM5 aconitate hydratase AK38_RS02945 ENOG4107R11 Transcriptional regulator AK38_RS02950 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AK38_RS02960 ENOG4105RKX Protein of unknown function (DUF2498) AK38_RS02965 ENOG4105ERU peptidase AK38_RS02970 ENOG4105UBK short-chain dehydrogenase reductase AK38_RS02975 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase AK38_RS02980 ENOG4105FE9 pseudouridine synthase AK38_RS02985 ENOG4107RTD sua5 ycio yrdc ywlc family protein AK38_RS02990 ENOG4105DB7 PHP domain protein AK38_RS03010 ENOG4105DDQ anthranilate synthase AK38_RS03020 ENOG4105DK0 Indole-3-glycerol phosphate synthase AK38_RS03040 ENOG4105EIF outer membrane protein W AK38_RS03070 ENOG4105NAU thioesterase Superfamily protein AK38_RS03080 ENOG410822N TonB family AK38_RS03085 ENOG4105K9H YciI-like protein AK38_RS03100 ENOG4108T1M outer membrane protein x AK38_RS03125 ENOG4108JQ7 (ABC) transporter AK38_RS03130 ENOG4105C3U ABC transporter AK38_RS03135 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_RS03140 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_RS03145 ENOG4107QSI ABC, transporter AK38_RS03150 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein AK38_RS03155 ENOG4105C0A alcohol dehydrogenase AK38_RS03180 ENOG4105C6Y Udp-glucose 6-dehydrogenase AK38_RS03185 ENOG4105I93 response regulator AK38_RS03195 ENOG4105CIY formyltetrahydrofolate deformylase AK38_RS03220 ENOG4105SKE transcriptional Regulator LysR family AK38_RS03225 ENOG4105CGK Exodeoxyribonuclease III AK38_RS03230 ENOG4105M6F mutator MutT protein AK38_RS03235 ENOG4105MTM Protein of unknown function (DUF1496) AK38_RS03240 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) AK38_RS03245 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) AK38_RS03250 ENOG41069NU Nitroreductase AK38_RS03255 ENOG4105D07 Signal peptide peptidase, SppA AK38_RS03260 ENOG4105HDK L-asparaginase AK38_RS03265 ENOG4108RWI nicotinamidase AK38_RS03270 ENOG4105VUT cytoplasmic protein AK38_RS03285 ENOG4105DSB aldose 1-epimerase AK38_RS03290 ENOG4105GNX MltA-interacting MipA family protein AK38_RS03295 ENOG4105CYN Serine protein kinase AK38_RS03310 ENOG4105HEI LysR family (Transcriptional regulator AK38_RS03315 ENOG4105EUB pirin domain protein AK38_RS03320 ENOG4105CNH Multidrug resistance protein MdtL AK38_RS03330 ENOG4105ED1 spovr family AK38_RS03360 ENOG4105C3J Cysteine desulfurase AK38_RS03380 ENOG4105UZW Tail fiber assembly protein AK38_RS03610 ENOG4105HRS Antitermination protein AK38_RS03620 ENOG4105NY2 NinB protein AK38_RS03660 ENOG4107R08 Integrase AK38_RS03670 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase AK38_RS03675 ENOG4105CVE Lytic murein transglycosylase AK38_RS03690 ENOG4107QMS site-determining protein AK38_RS03695 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) AK38_RS03700 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) AK38_RS03705 ENOG4105CEY Amp-dependent synthetase and ligase AK38_RS03710 ENOG4105Y4Z Outer Membrane Lipoprotein AK38_RS03715 ENOG41072GX Peptidase M22 Glycoprotease AK38_RS03720 ENOG4105DVT helicase AK38_RS03725 ENOG4105M4H endoribonuclease L-psp AK38_RS03740 ENOG4108UHU Aldolase AK38_RS03745 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase AK38_RS03750 ENOG4106KNT transcriptional regulator AK38_RS03755 ENOG4105CA9 Pyruvate kinase AK38_RS03760 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase AK38_RS03765 ENOG4105DR5 peptidase AK38_RS03770 ENOG4105NXV High-affinity zinc uptake system protein AK38_RS03780 ENOG4105FAV ABC, transporter AK38_RS03805 ENOG4108TIT dATP pyrophosphohydrolase AK38_RS03815 ENOG41081XQ Conserved Protein AK38_RS03820 ENOG4105WJG Glutathione AK38_RS03840 ENOG4106ZCM YecM protein AK38_RS03865 ENOG4105CJR Integral membrane protein (MviN AK38_RS03875 ENOG4105D9U N-acetyltransferase AK38_RS03885 ENOG4105F3T (LipO)protein AK38_RS03890 ENOG4107XHZ cytoplasmic chaperone TorD family protein AK38_RS03905 ENOG4105E2R ROK family AK38_RS03910 ENOG4108QXE glycerophosphoryl diester phosphodiesterase AK38_RS03930 ENOG4105F38 ABC transporter, permease AK38_RS03935 ENOG4105EG2 ABC transporter, permease AK38_RS03975 ENOG4105CHH sulfate transporter AK38_RS03980 ENOG4108RS6 transposase AK38_RS03990 ENOG41063JG Transcriptional regulator AK38_RS03995 ENOG4108YY7 Invasion gene expression up-regulator SirB AK38_RS04000 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) AK38_RS04030 ENOG4105C5T Phosphoribosyl pyrophosphate synthase AK38_RS04040 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria AK38_RS04050 ENOG4105C3G gtp-binding protein AK38_RS04095 ENOG4105ENX hydrolase AK38_RS04105 ENOG4105GR3 Histidine kinase AK38_RS04145 ENOG4108WF3 methyltransferase AK38_RS04215 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AK38_RS04235 ENOG41090B9 response to stress AK38_RS04240 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) AK38_RS04245 ENOG4105CZE histidine utilization repressor AK38_RS04305 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component AK38_RS04320 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) AK38_RS04415 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_RS04470 ENOG4105WH1 Two component transcriptional regulator luxr family AK38_RS04475 ENOG4105XVG cytoplasmic protein AK38_RS04480 ENOG4105RA2 Membrane AK38_RS04490 ENOG4108T1M outer membrane protein x AK38_RS04500 ENOG4105C85 amino acid AK38_RS04520 ENOG410650H (LipO)protein AK38_RS04525 ENOG4105EKT )-iron permease AK38_RS04530 ENOG4105CK7 Sodium proline symporter AK38_RS04540 ENOG4105C26 Dehydrogenase AK38_RS04555 ENOG4105CDA abc transporter atp-binding protein AK38_RS04560 ENOG4105E5Q amino acid AbC transporter AK38_RS04565 ENOG4105EAB amino acid AbC transporter AK38_RS04575 ENOG4108M9K flagella biosynthesis protein FliZ AK38_RS04580 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_RS04585 ENOG4105I03 Flagellin AK38_RS04590 ENOG4105DTS flagellar hook-associated AK38_RS04595 ENOG4105MQ3 flagellar protein FliS AK38_RS04610 ENOG4108NKV transcriptional regulator AK38_RS04615 ENOG4108T5G Adenylate AK38_RS04620 ENOG4105DHT Metal Dependent Phosphohydrolase AK38_RS04640 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AK38_RS04645 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AK38_RS04650 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AK38_RS04655 ENOG41090PJ Flagellar assembly protein AK38_RS04660 ENOG4108JIR Flagellum-specific ATP synthase AK38_RS04665 ENOG4105GSA Flagellar export protein flij AK38_RS04670 ENOG4105WF4 Flagellar hook-length control protein AK38_RS04675 ENOG4107ZI8 flagellar basal body-associated protein flil AK38_RS04680 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) AK38_RS04685 ENOG4105DD5 Flagellar motor switch protein AK38_RS04695 ENOG4105CN7 Flagellar biosynthetic protein FliP AK38_RS04705 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AK38_RS04720 ENOG4108MGF sugar kinase AK38_RS04725 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AK38_RS04730 ENOG4105C2J ABC transporter AK38_RS04740 ENOG4105CNN ABC, transporter AK38_RS04750 ENOG4105DKT Transcriptional regulator AK38_RS04755 ENOG4105DTJ flagellar hook-associated protein AK38_RS04760 ENOG4105E1Q flagellar hook-associated protein AK38_RS04765 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj AK38_RS04780 ENOG4105CGA flagellar basal-body rod protein FlgG AK38_RS04790 ENOG4105BZE flagellar hook protein, FlgE AK38_RS04795 ENOG4105W00 Flagellar hook capping protein AK38_RS04800 ENOG4108ZC9 flagellar basal-body rod protein flgc AK38_RS04805 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AK38_RS04810 ENOG4105CKS Flagella basal body P-ring formation protein flgA AK38_RS04815 ENOG4105M9M anti-sigma28 factor FlgM AK38_RS04820 ENOG4105QVD Flagella synthesis protein FlgN AK38_RS04840 ENOG4105W13 flagellar protein AK38_RS04845 ENOG4105D7B Flagellar biosynthesis protein flha AK38_RS04850 ENOG4105D00 flagellar biosynthetic protein flhB AK38_RS04870 ENOG4105NKT exported protein AK38_RS04880 ENOG4105FXM Copper resistance protein AK38_RS04885 ENOG41090A1 ferritin AK38_RS04890 ENOG4105MPK DNA polymerase III subunit theta AK38_RS04900 ENOG4105CUG Oligopeptidase b AK38_RS04915 ENOG4105X2V dna damage-inducible protein AK38_RS04920 ENOG4105C1J atp-dependent rna helicase AK38_RS04935 ENOG4105CRQ synthase (Component I) AK38_RS04945 ENOG4105EJQ L-serine dehydratase AK38_RS04950 ENOG4107UWN reductase AK38_RS04955 ENOG4105EFA 4-hydroxyphenylacetate AK38_RS04980 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase AK38_RS04985 ENOG4105C26 Dehydrogenase AK38_RS05000 ENOG4108V8F Transcriptional regulator, MarR family AK38_RS05005 ENOG4105EE5 Membrane protein terC AK38_RS05010 ENOG4105DAS pts system AK38_RS05015 ENOG4105ETZ PTS System AK38_RS05020 ENOG4105F3R pts system mannose fructose sorbose family iid AK38_RS05040 ENOG4105BZU Histidine kinase AK38_RS05065 ENOG4105DHI Methyltransferase AK38_RS05070 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AK38_RS05095 ENOG4105C85 amino acid AK38_RS05110 ENOG41064PC AK38_RS05115 ENOG4105TIK AK38_RS05120 ENOG4105N4N Protein of unknown function (DUF2766) AK38_RS05140 ENOG4105BZ1 (ABC) transporter AK38_RS05195 ENOG4105M5J Cupin 2, conserved barrel domain protein AK38_RS05205 ENOG4105CHR reductase AK38_RS05210 ENOG41061NF Pectate lyase AK38_RS05215 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component AK38_RS05220 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component AK38_RS05230 ENOG4105WEM extracellular solute-binding protein AK38_RS05235 ENOG4108PU9 oligogalacturonate-specific porin AK38_RS05240 ENOG4107K5X Membrane-bound metal-dependent hydrolase AK38_RS05245 ENOG4108ETY sodium dicarboxylate symporter AK38_RS05250 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AK38_RS05260 ENOG4105CAZ oligogalacturonide lyase AK38_RS05265 ENOG4105C0R drug resistance transporter emrb qaca subfamily AK38_RS05270 ENOG4108VEV chaperone AK38_RS05285 ENOG4108VEV chaperone AK38_RS05290 ENOG4105H8W Fimbrial protein AK38_RS05300 ENOG4105CN1 protease AK38_RS05310 ENOG4108ZGC gaf domain protein AK38_RS05315 ENOG4105H2K paraquat-inducible protein a AK38_RS05320 ENOG4105DY2 Paraquat-inducible protein b AK38_RS05340 ENOG4105GQR Chaperone AK38_RS05355 ENOG4105WT8 Protein of unknown function (DUF1480) AK38_RS05395 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) AK38_RS05405 ENOG4105EUR Domain-Containing protein AK38_RS05410 ENOG4105EUR Domain-Containing protein AK38_RS05415 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AK38_RS05425 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) AK38_RS05430 ENOG4108VYJ response regulator receiver protein AK38_RS05440 ENOG4105BZU Histidine kinase AK38_RS05455 ENOG4105C8Q Methyl-accepting chemotaxis AK38_RS05475 ENOG4105WWK YheO domain protein AK38_RS05485 ENOG4105KME endoribonuclease L-psp AK38_RS05490 ENOG4105R9B Major Facilitator AK38_RS05495 ENOG4108V3W Chemotaxis protein, CheW AK38_RS05500 ENOG4105CBS Chea signal transduction histidine kinase AK38_RS05505 ENOG4105ER2 Ompa motb domain protein AK38_RS05510 ENOG4107RD7 Flagellar Motor Protein, MotA AK38_RS05515 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region AK38_RS05525 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic AK38_RS05530 ENOG4105KT7 mgtC SapB transporter AK38_RS05565 ENOG4105GSJ Inner membrane protein ylaC AK38_RS05570 ENOG4108XM1 transcriptional regulator AsnC family AK38_RS05580 ENOG41061EV selenium-binding protein YdfZ AK38_RS05585 ENOG4105D6F Phosphatase AK38_RS05595 ENOG4105KVH Transcriptional regulator AK38_RS05600 ENOG4105ECR NmrA family AK38_RS05605 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor AK38_RS05615 ENOG4106NDP Transcriptional regulator AK38_RS05620 ENOG4108HMX isocitrate dehydrogenase (NADP) AK38_RS05625 ENOG4108R99 pseudouridine synthase AK38_RS05645 ENOG4107QTF adenylosuccinate lyase AK38_RS05655 ENOG4105XJC Two component transcriptional regulator (Winged helix family AK38_RS05665 ENOG4105EZE Cupin 4 family protein AK38_RS05685 ENOG4105D60 lipoprotein releasing system transmembrane protein AK38_RS05695 ENOG4105D60 lipoprotein releasing system transmembrane protein AK38_RS05700 ENOG4108JA2 transcriptioN-repair coupling factor AK38_RS05705 ENOG4107MBR 17 kDa surface antigen AK38_RS05735 ENOG4105CEP NADH dehydrogenase AK38_RS05745 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) AK38_RS05760 ENOG41090DQ Lipoprotein AK38_RS05765 ENOG4105K59 histidine triad (HIT) protein AK38_RS05770 ENOG4105F9E Shikimate 5-dehydrogenase AK38_RS05780 ENOG4105CI1 PTS System AK38_RS05785 ENOG4105F8V Hydrolase, tatD family AK38_RS05790 ENOG4107QRG dna polymerase iii AK38_RS05800 ENOG4105HHA aminodeoxychorismate lyase AK38_RS05805 ENOG4105YAZ 4-amino-4-deoxychorismate lyase AK38_RS05810 ENOG4108RS6 transposase AK38_RS05815 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_RS05825 ENOG4105CHR reductase AK38_RS05830 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AK38_RS05845 ENOG4105VGS 50s ribosomal protein l32 AK38_RS05850 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein AK38_RS05855 ENOG4108UHJ MAF-like protein AK38_RS05870 ENOG4105EI2 Pseudouridine synthase AK38_RS05875 ENOG4107QQB Ribonuclease E AK38_RS05885 ENOG41067V3 Antibiotic biosynthesis monooxygenase AK38_RS05905 ENOG4105PVA Biofilm formation regulatory protein BssS AK38_RS05915 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) AK38_RS05930 ENOG4108TSE Transferase AK38_RS05935 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit AK38_RS05945 ENOG4105CG6 trap dicarboxylate transporter dctm subunit AK38_RS05950 ENOG4108KX4 response regulator AK38_RS05960 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme AK38_RS05980 ENOG4105UQX Mate efflux family protein AK38_RS05995 ENOG4105DIA mandelate racemase muconate lactonizing AK38_RS06005 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr AK38_RS06010 ENOG4105KIR Thiol-disulfide oxidoreductase dcc AK38_RS06015 ENOG4105CSP Major Facilitator Superfamily AK38_RS06020 ENOG4105TNG K13735 adhesin invasin AK38_RS06040 ENOG4105CJB Exodeoxyribonuclease I AK38_RS06045 ENOG4105CUB amino acid AK38_RS06055 ENOG4107SCQ Iron-containing alcohol dehydrogenase AK38_RS06060 ENOG4105C2J ABC transporter AK38_RS06065 ENOG4105C2J ABC transporter AK38_RS06070 ENOG4105CNN ABC, transporter AK38_RS06075 ENOG4107SRH Nad-dependent epimerase dehydratase AK38_RS06085 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) AK38_RS06095 ENOG4105ECC imidazole-glycerol-phosphate dehydratase AK38_RS06115 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase AK38_RS06120 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) AK38_RS06125 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AK38_RS06130 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase AK38_RS06135 ENOG4105DUU IucA IucC family protein AK38_RS06140 ENOG4105CNM Receptor AK38_RS06145 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) AK38_RS06150 ENOG4105DQ5 transport system permease protein AK38_RS06155 ENOG4105TVJ transport system, permease AK38_RS06160 ENOG4105E0A ABC, transporter AK38_RS06165 ENOG4105DUU IucA IucC family protein AK38_RS06175 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) AK38_RS06180 ENOG4105DY8 decarboxylase AK38_RS06185 ENOG4108819 ferric iron reductase AK38_RS06190 ENOG4105EE5 Membrane protein terC AK38_RS06195 ENOG4108GAE asmA family AK38_RS06210 ENOG4105D1F ATP-binding protein AK38_RS06220 ENOG4108RS6 transposase AK38_RS06255 ENOG4105E5W Transporter AK38_RS06265 ENOG41067MG lrgb family AK38_RS06280 ENOG4107GZ4 SanA protein AK38_RS06285 ENOG4108HWV )-transporter AK38_RS06300 ENOG4105DHF Membrane AK38_RS06310 ENOG4105CBP Major Facilitator AK38_RS06315 ENOG4105EGI Transcriptional regulator AK38_RS06340 ENOG4105ENT Efflux transporter rnd family, mfp subunit AK38_RS06345 ENOG4105C19 ABC transporter AK38_RS06355 ENOG4105CVM Molybdenum cofactor synthesis domain protein AK38_RS06360 ENOG4105D06 uba thif-type nad fad binding protein AK38_RS06375 ENOG4105C5H ABC transporter AK38_RS06470 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS06480 ENOG4105CDV Ompa motb domain protein AK38_RS06510 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase AK38_RS06515 ENOG41062T2 Acyl carrier protein AK38_RS06525 ENOG4105CHR reductase AK38_RS06530 ENOG4108KQ6 Enoyl-CoA hydratase AK38_RS06540 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase AK38_RS06545 ENOG4105CHR reductase AK38_RS06550 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_RS06555 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) AK38_RS06600 ENOG4108Z0T Part of a sulfur-relay system (By similarity) AK38_RS06620 ENOG4105K4P CoA-binding domain protein AK38_RS06635 ENOG41088T4 Helicase IV AK38_RS06640 ENOG410901E Membrane AK38_RS06645 ENOG4105EM2 membrane AK38_RS06650 ENOG4108RZ1 DNA transformation protein AK38_RS06670 ENOG4108RS6 transposase AK38_RS06680 ENOG4105DAN ATP-dependent protease AK38_RS06720 ENOG4108RS6 transposase AK38_RS06730 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) AK38_RS06740 ENOG4108Q2G (LipO)protein AK38_RS06745 ENOG4105DY2 Paraquat-inducible protein b AK38_RS06750 ENOG4105F1S paraquat-inducible protein a AK38_RS06755 ENOG4105C5H ABC transporter AK38_RS06765 ENOG4105QVC MOSC domain-containing protein AK38_RS06770 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) AK38_RS06780 ENOG4105CD8 aminopeptidase N AK38_RS06800 ENOG4105CGF Aromatic amino acid aminotransferase AK38_RS06805 ENOG4105C5X domain protein AK38_RS06810 ENOG4105EAQ (twin-arginine translocation) pathway signal AK38_RS06815 ENOG4105DIT ErfK YbiS YcfS YnhG family protein AK38_RS06845 ENOG4106371 Methyltransferase AK38_RS06855 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups AK38_RS06875 ENOG4105VEQ Cold shock protein AK38_RS06885 ENOG4105E32 cytoplasmic protein AK38_RS06900 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 AK38_RS06915 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) AK38_RS06945 ENOG4105HDK L-asparaginase AK38_RS06950 ENOG4105DDY UPF0142 protein ycaO AK38_RS06955 ENOG4105TMB Formate nitrite transporter AK38_RS06960 ENOG4105C6N Formate acetyltransferase AK38_RS06970 ENOG4105F1A Pyruvate formate-lyase AK38_RS06985 ENOG4105D1H recombination factor protein RarA AK38_RS06995 ENOG4105CNU cell division protein FtsK AK38_RS07000 ENOG4105EW9 transcriptional regulator AsnC family AK38_RS07005 ENOG4105C3M thioredoxin reductase AK38_RS07015 ENOG4108JJ9 ABC, transporter AK38_RS07020 ENOG4108JJ8 (ABC) transporter AK38_RS07040 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS07050 ENOG4105VEQ Cold shock protein AK38_RS07060 ENOG4105DJY efflux transporter, rnd family, mfp subunit AK38_RS07065 ENOG4108MJ5 VirK protein AK38_RS07070 ENOG4105CPB ATP-dependent endonuclease of the OLD family AK38_RS07075 ENOG4105DWU Membrane AK38_RS07085 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AK38_RS07090 ENOG4105C7K acetolactate synthase AK38_RS07095 ENOG4105C5W Aldolase AK38_RS07100 ENOG4105CGD Nad-dependent epimerase dehydratase AK38_RS07105 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase AK38_RS07110 ENOG41064MM (LipO)protein AK38_RS07115 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) AK38_RS07120 ENOG4105E5Z arginine transporter ATP-binding subunit AK38_RS07125 ENOG4106PMH Extracellular solute-binding protein family 3 AK38_RS07130 ENOG4105GBT ABC transporter AK38_RS07135 ENOG4105DMR ABC, transporter AK38_RS07140 ENOG4108I0N Transporter, RarD family, DMT superfamily protein AK38_RS07145 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) AK38_RS07150 ENOG410642S Nicotianamine synthase protein AK38_RS07155 ENOG4105E0A ABC, transporter AK38_RS07210 ENOG4105RBQ inner membrane protein ybjO AK38_RS07215 ENOG4105D38 putrescine abc transporter AK38_RS07220 ENOG4105F38 ABC transporter, permease AK38_RS07225 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_RS07230 ENOG4107RUE extracellular solute-binding protein family 1 AK38_RS07235 ENOG4108RMJ sensory transduction regulator AK38_RS07245 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress AK38_RS07250 ENOG41090BQ Glutaredoxin AK38_RS07265 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase AK38_RS07275 ENOG4107FB0 transcriptional regulator DeoR family AK38_RS07280 ENOG4105C44 Serine transporter AK38_RS07290 ENOG4105DZ1 carboxypeptidase AK38_RS07295 ENOG4108UMI ABC transporter, permease AK38_RS07305 ENOG4105D01 (LipO)protein AK38_RS07320 ENOG4108TGY Glutathione S-transferase AK38_RS07325 ENOG4105D05 Receptor AK38_RS07335 ENOG4105EHG Permease protein AK38_RS07345 ENOG4108IQI permease AK38_RS07350 ENOG4105DUM transcriptional regulator, lysR family AK38_RS07355 ENOG4105HMI Membrane AK38_RS07365 ENOG4108D1K outer membrane usher protein AK38_RS07370 ENOG4108UIF Chaperone AK38_RS07385 ENOG4108SGD regulatory protein AK38_RS07390 ENOG4105DM4 PTS System AK38_RS07395 ENOG4105DE4 1-phosphofructokinase AK38_RS07400 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein AK38_RS07410 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane AK38_RS07415 ENOG4105C2J ABC transporter AK38_RS07435 ENOG4105C26 Dehydrogenase AK38_RS07450 ENOG4105CHR reductase AK38_RS07455 ENOG4105KRS Proteinase inhibitor AK38_RS07475 ENOG4105DEI Mannitol dehydrogenase AK38_RS07480 ENOG4107YCY Transcriptional regulator AK38_RS07490 ENOG4105CKI cobalamin synthesis protein AK38_RS07495 ENOG41076MN Phosphoesterase, PA-phosphatase related AK38_RS07500 ENOG4107TT5 NLP P60 protein AK38_RS07505 ENOG4105CXC rtn protein AK38_RS07510 ENOG4105E43 Extracellular solute-binding protein, family 5 AK38_RS07515 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component AK38_RS07520 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component AK38_RS07525 ENOG4108JQ5 ABC transporter AK38_RS07530 ENOG4105HG6 AK38_RS07535 ENOG4105C2C drug resistance transporter, Bcr CflA AK38_RS07540 ENOG4105I08 Pseudouridine synthase AK38_RS07545 ENOG4105CFI type iii restriction protein res subunit AK38_RS07555 ENOG4108RS6 transposase AK38_RS07570 ENOG4105PAN UPF0352 protein AK38_RS07575 ENOG4105E68 Sulfatase AK38_RS07605 ENOG4105CS2 ec 3.2.1.21 AK38_RS07610 ENOG4108Q3X Transcriptional regulator AK38_RS07630 ENOG4108T86 baseplate J family protein AK38_RS07670 ENOG4105TKZ Tail Sheath AK38_RS07690 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) AK38_RS07695 ENOG4105MVE transcriptional regulator AK38_RS07705 ENOG4105G63 Type III effector Hrp-dependent AK38_RS07710 ENOG4105HRS Antitermination protein AK38_RS07720 ENOG4105Y50 Virulence Protein AK38_RS07730 ENOG4105C8Q Methyl-accepting chemotaxis AK38_RS07740 ENOG4105CT4 transporter AK38_RS07750 ENOG4107R6D beta-lactam binding protein AmpH AK38_RS07775 ENOG4108RS6 transposase AK38_RS07780 ENOG4105FCK Membrane AK38_RS07785 ENOG4106UW1 Major Facilitator superfamily AK38_RS07790 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC AK38_RS07795 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC AK38_RS07800 ENOG41068CG regulatoR AK38_RS07805 ENOG4105BZU Histidine kinase AK38_RS07815 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_RS07825 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AK38_RS07830 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AK38_RS07835 ENOG4105XPH Ferredoxin AK38_RS07850 ENOG4105E0U tyrosine-specific transport protein AK38_RS07855 ENOG4108UII YfaZ family AK38_RS07860 ENOG4105CH6 catalase AK38_RS07865 ENOG4105DVT helicase AK38_RS07875 ENOG4105FDR Membrane AK38_RS07885 ENOG4105CXN decarboxylase AK38_RS07890 ENOG4105D5Q Arginine ornithine antiporter AK38_RS07895 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component AK38_RS07900 ENOG4108IJ8 ABC transporter AK38_RS07905 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component AK38_RS07920 ENOG4105KHC sulfurtransferase AK38_RS07935 ENOG4108IV0 ABC, transporter AK38_RS07940 ENOG4108JJB ABC transporter AK38_RS07945 ENOG4105CNN ABC, transporter AK38_RS07950 ENOG4105C32 Amino acid ABC transporter (Permease) AK38_RS07960 ENOG4108W15 Protein of unknown function (DUF1456) AK38_RS07975 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein AK38_RS07985 ENOG4105Y3U Transglycosylase-associated protein AK38_RS07995 ENOG4105N1F Hnh endonuclease AK38_RS08005 ENOG4105CXG d-lactate dehydrogenase AK38_RS08010 ENOG41061WM D-Alanyl-D-Alanine AK38_RS08020 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) AK38_RS08030 ENOG4108RS6 transposase AK38_RS08040 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) AK38_RS08050 ENOG4105CN8 Transcriptional regulator AK38_RS08055 ENOG4105C94 Transporter AK38_RS08075 ENOG4108RS6 transposase AK38_RS08085 ENOG4105HFZ Membrane AK38_RS08090 ENOG4108ZAF Molybdopterin AK38_RS08095 ENOG4105M00 molybdopterin converting factor, subunit 1 AK38_RS08105 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) AK38_RS08115 ENOG4105CHW UPF0052 protein AK38_RS08120 ENOG4105VYA Uncharacterized conserved protein (DUF2132) AK38_RS08140 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) AK38_RS08165 ENOG4108K4B hydrolase AK38_RS08175 ENOG4105E0C molybdate abc transporter AK38_RS08180 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein AK38_RS08190 ENOG4105F4R Transcriptional regulator mode AK38_RS08195 ENOG4105DKW ABC transporter AK38_RS08210 ENOG4105CMR udp-glucose 4-epimerase AK38_RS08215 ENOG4105F0Z galactose-1-phosphate uridylyltransferase AK38_RS08230 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) AK38_RS08245 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_RS08260 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_RS08265 ENOG4105PGM cation diffusion facilitator family transporter AK38_RS08270 ENOG4106Z1T Nicotinamide Mononucleotide Transporter AK38_RS08295 ENOG4105UFD tol-pal system protein YbgF AK38_RS08300 ENOG4105KCK Peptidoglycan-associated lipoprotein AK38_RS08310 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA AK38_RS08310 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA AK38_RS08320 ENOG4105E02 MotA TolQ exbB proton channel AK38_RS08325 ENOG4107YD3 Thioesterase AK38_RS08330 ENOG4105KJB cyd operon protein YbgE AK38_RS08340 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii AK38_RS08345 ENOG4105C4M (Ubiquinol oxidase) subunit I AK38_RS08350 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha AK38_RS08360 ENOG4105C7S Dehydrogenase AK38_RS08365 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 AK38_RS08370 ENOG4105E33 succinate dehydrogenase AK38_RS08380 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein AK38_RS08385 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit AK38_RS08390 ENOG4105BZN citrate synthase AK38_RS08400 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) AK38_RS08405 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) AK38_RS08410 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AK38_RS08420 ENOG4108Z1B Cyclase dehydrase AK38_RS08440 ENOG4108RS6 transposase AK38_RS08445 ENOG4105DFP Integrase AK38_RS08505 ENOG4105VUH addiction module killer protein AK38_RS08540 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease AK38_RS08550 ENOG4107RZZ dna polymerase iii epsilon subunit AK38_RS08560 ENOG4105D1A Methyltransferase AK38_RS08565 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) AK38_RS08570 ENOG4105E9H Lytic Murein transglycosylase AK38_RS08585 ENOG4105CV8 reductase AK38_RS08615 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase AK38_RS08625 ENOG4108UMI ABC transporter, permease AK38_RS08630 ENOG4105D01 (LipO)protein AK38_RS08635 ENOG4108R8X outer membrane lipoprotein AK38_RS08640 ENOG4108R96 Methyltransferase, YaeB family AK38_RS08650 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion AK38_RS08655 ENOG4108YZN class I peptide chain release factor AK38_RS08660 ENOG4108VWS Yaeq family AK38_RS08670 ENOG4105M1T rho-binding antiterminator AK38_RS08680 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) AK38_RS08685 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase AK38_RS08695 ENOG4105C0B DNA polymerase III (alpha subunit) AK38_RS08720 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) AK38_RS08735 ENOG4105DZP Membrane-associated zinc metalloprotease AK38_RS08740 ENOG4105KNE Phosphatidate cytidylyltransferase AK38_RS08775 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AK38_RS08795 ENOG4105QDK Flavodoxin AK38_RS08800 ENOG4105DR9 pseudouridine synthase AK38_RS08805 ENOG4105WP7 tRNA pseudouridine synthase C AK38_RS08810 ENOG4108RS6 transposase AK38_RS08825 ENOG4105EWT decarboxylase family AK38_RS08840 ENOG4105M08 Membrane AK38_RS08845 ENOG4105ETT transcriptional Regulator, LysR family AK38_RS08850 ENOG4105C9B Cysteine desulfurase AK38_RS08855 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) AK38_RS08860 ENOG4105CUZ uba thif-type nad fad binding protein AK38_RS08865 ENOG4105CA3 membrane-bound lytic murein transglycosylase AK38_RS08880 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AK38_RS08890 ENOG4107QYX exodeoxyribonuclease v alpha AK38_RS08895 ENOG4107QKA exodeoxyribonuclease V beta AK38_RS08900 ENOG4107QXK peptidase AK38_RS08905 ENOG4105DSY exodeoxyribonuclease V, gamma AK38_RS08940 ENOG4107ZSV Receptor AK38_RS08945 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) AK38_RS08950 ENOG4105CFC Transporter AK38_RS08990 ENOG4105C1P efflux transporter, rnd family, mfp subunit AK38_RS09015 ENOG4105CT4 transporter AK38_RS09025 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) AK38_RS09030 ENOG4105DUU IucA IucC family protein AK38_RS09120 ENOG4105CDV Ompa motb domain protein AK38_RS09130 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS09205 ENOG4105CXN decarboxylase AK38_RS09210 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_RS09215 ENOG4105C2J ABC transporter AK38_RS09220 ENOG4105CNN ABC, transporter AK38_RS09245 ENOG4105CEN a g-specific adenine glycosylase AK38_RS09255 ENOG41090ED Protein with unknown function (DUF469) AK38_RS09275 ENOG4105EUK rtx toxin RtxA AK38_RS09280 ENOG4105CSA Coproporphyrinogen iii oxidase AK38_RS09285 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) AK38_RS09295 ENOG4108VIA integral membrane protein AK38_RS09300 ENOG4105II7 pyrroline-5-carboxylate reductase AK38_RS09305 ENOG4105DFA alanine racemase domain protein AK38_RS09310 ENOG4105CZX twitching motility protein AK38_RS09320 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) AK38_RS09335 ENOG4105D7Z glutathione synthase AK38_RS09340 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) AK38_RS09345 ENOG4105RWS endonuclease I AK38_RS09350 ENOG4105GPY SprT protein AK38_RS09360 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) AK38_RS09370 ENOG4108K0D peptidase, M48 AK38_RS09375 ENOG4105CV1 Transketolase (EC 2.2.1.1) AK38_RS09405 ENOG4105D2N Aldolase AK38_RS09410 ENOG4105D64 Mechanosensitive ion channel AK38_RS09420 ENOG4105MPN Membrane AK38_RS09435 ENOG4108JQ1 Dehydrogenase AK38_RS09440 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase AK38_RS09460 ENOG4107RAQ aminopeptidase AK38_RS09465 ENOG4105D0A hydroxylase AK38_RS09470 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AK38_RS09510 ENOG4108UT2 hemolysin iii AK38_RS09535 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_RS09540 ENOG4105EB3 Histidine kinase AK38_RS09545 ENOG4105CT7 inner membrane cred family protein AK38_RS09550 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) AK38_RS09555 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AK38_RS09560 ENOG4105T95 Thiol disulfide interChange protein AK38_RS09565 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) AK38_RS09585 ENOG4105DFP Integrase AK38_RS09610 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation AK38_RS09615 ENOG4105WJ3 XRE family Transcriptional regulator AK38_RS09710 ENOG4105NTW Transcriptional regulator AK38_RS09715 ENOG4108UY0 (LipO)protein AK38_RS09725 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_RS09730 ENOG4105CNN ABC, transporter AK38_RS09745 ENOG4107FKK extracellular solute-binding protein family 1 AK38_RS09755 ENOG4105EG2 ABC transporter, permease AK38_RS09765 ENOG4105C4C beta-galactosidase AK38_RS09770 ENOG4105CI1 PTS System AK38_RS09780 ENOG4105ETE Transcriptional regulator (LacI family AK38_RS09790 ENOG4105DPW Major facilitator superfamily MFS_1 AK38_RS09795 ENOG4105ETE Transcriptional regulator (LacI family AK38_RS09810 ENOG4105D2N Aldolase AK38_RS09820 ENOG4105ENH Sulfatase AK38_RS09825 ENOG4105C4X radical SAM domain protein AK38_RS09835 ENOG4105CHR reductase AK38_RS09840 ENOG4105CE4 GlcNAc 6-P deacetylase AK38_RS09845 ENOG4108YTN IIa component AK38_RS09850 ENOG4105F3R pts system mannose fructose sorbose family iid AK38_RS09855 ENOG4105ETZ PTS System AK38_RS09860 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB AK38_RS09865 ENOG4105E70 isomerase AK38_RS09870 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of AK38_RS09875 ENOG4105E98 transcriptional regulator DeoR family AK38_RS09880 ENOG4105CBG Sulfatase AK38_RS09885 ENOG4108RS6 transposase AK38_RS09930 ENOG4107B2H carbonic anhydrase AK38_RS09950 ENOG4107QHF type ii secretion system protein e AK38_RS10020 ENOG4105C8Q Methyl-accepting chemotaxis AK38_RS10035 ENOG4105EJC lysr family transcriptional regulator AK38_RS10040 ENOG4105F27 Major Facilitator AK38_RS10045 ENOG4105RQF LysR family Transcriptional regulator AK38_RS10055 ENOG41060NJ transcriptional regulator AK38_RS10085 ENOG4105CPC Aldo Keto reductase AK38_RS10110 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase AK38_RS10150 ENOG4105C0W non-ribosomal peptide synthetase AK38_RS10160 ENOG4105C0W non-ribosomal peptide synthetase AK38_RS10190 ENOG4105BZ1 (ABC) transporter AK38_RS10205 ENOG4107EFN gluconate transport system permease 3 AK38_RS10220 ENOG4105CS6 Rhs element vgr protein AK38_RS10230 ENOG4105CNA YD repeat protein AK38_RS10240 ENOG41062WK cellular response to acidity AK38_RS10245 ENOG4105C8P )-transporter AK38_RS10250 ENOG4105ETE Transcriptional regulator (LacI family AK38_RS10300 ENOG4107RD7 Flagellar Motor Protein, MotA AK38_RS10330 ENOG410804A Flagellar hook-associated 2 domain-containing protein AK38_RS10350 ENOG4108M3R transcriptional activator CadC AK38_RS10370 ENOG4105E1Q flagellar hook-associated protein AK38_RS10380 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) AK38_RS10390 ENOG4105CGA flagellar basal-body rod protein FlgG AK38_RS10395 ENOG4108KPB Flagellar basal-body rod protein FlgF AK38_RS10415 ENOG4105BZE flagellar hook protein, FlgE AK38_RS10420 ENOG4105W00 Flagellar hook capping protein AK38_RS10425 ENOG4108ZC9 flagellar basal-body rod protein flgc AK38_RS10430 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) AK38_RS10435 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA AK38_RS10455 ENOG4108JIR Flagellum-specific ATP synthase AK38_RS10470 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) AK38_RS10475 ENOG4105VQ0 flagellar hook-basal body complex protein fliE AK38_RS10490 ENOG4105DD5 Flagellar motor switch protein AK38_RS10495 ENOG4105CN7 Flagellar biosynthetic protein FliP AK38_RS10500 ENOG4105VS8 Flagellar biosynthetic protein fliq AK38_RS10505 ENOG4105D19 Role in flagellar biosynthesis (By similarity) AK38_RS10510 ENOG4105D00 flagellar biosynthetic protein flhB AK38_RS10530 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein AK38_RS10540 ENOG4106P2F Pfam:Pili_assembly_C AK38_RS10545 ENOG4106PG1 outer membrane usher protein AK38_RS10560 ENOG4108RS6 transposase AK38_RS10630 ENOG4108ZZF transport protein (ExbD) AK38_RS10635 ENOG4105CWK Biopolymer transport protein, ExbB AK38_RS10640 ENOG4105C28 cystathionine AK38_RS10645 ENOG4108K81 inner membrane protein YghB AK38_RS10650 ENOG4105CF7 AraC family transcriptional regulator AK38_RS10655 ENOG4108I6A alcohol dehydrogenase AK38_RS10665 ENOG4105CV8 reductase AK38_RS10675 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) AK38_RS10680 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase AK38_RS10685 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_RS10695 ENOG4105NF4 modulator of drug activity AK38_RS10700 ENOG4105CR8 Transcriptional regulator AK38_RS10705 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_RS10710 ENOG4105IPS esterase AK38_RS10715 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) AK38_RS10720 ENOG4108SX3 cytoplasmic protein AK38_RS10725 ENOG41087AY ADP-Ribose pyrophosphatase AK38_RS10730 ENOG4105DFG type I secretion outer membrane protein AK38_RS10745 ENOG4106032 Glutathionylspermidine synthase AK38_RS10750 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b AK38_RS10760 ENOG4105W0Z cytoplasmic protein AK38_RS10765 ENOG4105DVH amino acid AK38_RS10780 ENOG4105I7R Adenylate cyclase AK38_RS10785 ENOG4106MWK domain protein AK38_RS10800 ENOG4107ZVW dihydroneopterin aldolase AK38_RS10820 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) AK38_RS10825 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_RS10915 ENOG4105KME endoribonuclease L-psp AK38_RS10955 ENOG4105J12 Multidrug resistance protein mdtN AK38_RS10960 ENOG4108MI0 Resistance protein AK38_RS10970 ENOG4107QK4 glycoside hydrolase, family 3 domain protein AK38_RS10980 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component AK38_RS10995 ENOG4107KJX Transcriptional regulator AK38_RS11000 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 AK38_RS11025 ENOG4105CKT filamentous hemagglutinin AK38_RS11050 ENOG4105CKT filamentous hemagglutinin AK38_RS11055 ENOG4105D5K Hemolysin activator protein AK38_RS11060 ENOG4108M24 von Willebrand factor, type A AK38_RS11075 ENOG4108M24 von Willebrand factor, type A AK38_RS11095 ENOG4108YK4 Acid-resistance membrane protein AK38_RS11100 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase AK38_RS11115 ENOG4108VKG metal-dependent hydrolase AK38_RS11120 ENOG4105EE0 oxidoreductase AK38_RS11130 ENOG4108RS6 transposase AK38_RS11135 ENOG4105P66 Membrane AK38_RS11140 ENOG4105CTX dehydratase AK38_RS11160 ENOG4105DPW Major facilitator superfamily MFS_1 AK38_RS11175 ENOG4106W5V Membrane AK38_RS11195 ENOG4105NE1 Conserved Protein AK38_RS11200 ENOG41090KG Inner membrane protein YqjE AK38_RS11210 ENOG4108VBZ doxx family AK38_RS11230 ENOG4105M6F mutator MutT protein AK38_RS11255 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) AK38_RS11260 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) AK38_RS11265 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) AK38_RS11285 ENOG4105CNI cell division protein FtsW AK38_RS11300 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) AK38_RS11305 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) AK38_RS11310 ENOG4105CJN penicillin-binding protein AK38_RS11315 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) AK38_RS11330 ENOG4108RNS Exports L-alanine (By similarity) AK38_RS11335 ENOG4107B7Y DNA-binding transcriptional regulator FruR AK38_RS11350 ENOG4108ZP8 Acetolactate synthase small subunit AK38_RS11355 ENOG4105C7K acetolactate synthase AK38_RS11365 ENOG4108IQE Amp-dependent synthetase and ligase AK38_RS11375 ENOG41064T2 transcriptional regulator, lysR family AK38_RS11390 ENOG4108RS6 transposase AK38_RS11400 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) AK38_RS11415 ENOG4105S8Q sugar efflux transporter AK38_RS11450 ENOG4105DP9 ABC transporter AK38_RS11455 ENOG4106SMU thiamine transporter membrane protein AK38_RS11460 ENOG4107T0D ABC, transporter AK38_RS11465 ENOG4108KF1 Membrane AK38_RS11470 ENOG4105CQ2 DNA polymerase AK38_RS11530 ENOG4105CS6 Rhs element vgr protein AK38_RS11535 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS11580 ENOG4105D3G Pseudouridine synthase AK38_RS11585 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) AK38_RS11630 ENOG4108RS6 transposase AK38_RS11640 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) AK38_RS11650 ENOG4105DWK Membrane AK38_RS11655 ENOG4105N14 lysine exporter protein LysE YggA AK38_RS11660 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain AK38_RS11675 ENOG4108RS6 transposase AK38_RS11695 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase AK38_RS11710 ENOG4105DTN riboflavin biosynthesis protein ribF AK38_RS11725 ENOG41063Z6 transcriptional regulator, lysR family AK38_RS11745 ENOG4106HK8 GPR1 FUN34 yaaH family protein AK38_RS11755 ENOG4105CSH Transporter AK38_RS11760 ENOG4108RIR Molybdenum cofactor biosynthesis protein AK38_RS11790 ENOG41065U4 response regulator AK38_RS11795 ENOG4108RH0 Crea protein AK38_RS11800 ENOG4105UEI Transcriptional Regulator AraC Family AK38_RS11815 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) AK38_RS11820 ENOG4107SC1 transglycosylase AK38_RS11835 ENOG4108KHX Diguanylate cyclase AK38_RS11840 ENOG41090EK ompa motb domain protein AK38_RS11855 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase AK38_RS11860 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) AK38_RS11865 ENOG4105EAC phosphoserine phosphatase AK38_RS11870 ENOG41062Z9 Membrane AK38_RS11900 ENOG4105D9N nucleoside AK38_RS11905 ENOG4105EYA deoxyribonuclease AK38_RS11910 ENOG4108NRW Phospholipase, patatin family AK38_RS11920 ENOG4105K3G Periplasmic Protein AK38_RS11930 ENOG4105KEG ribosomal-protein-alanine acetyltransferase AK38_RS11935 ENOG4108WPU DNA polymerase III subunit psi AK38_RS11950 ENOG4105YBH Protein of unknown function (DUF1435) AK38_RS11955 ENOG4105BZU Histidine kinase AK38_RS11980 ENOG4105BZS acriflavin resistance protein AK38_RS11985 ENOG410624X efflux transporter, rnd family, mfp subunit AK38_RS12005 ENOG4105DKP glycosyl transferase, family 9 AK38_RS12010 ENOG4107RYS Autoinducer-2 (AI-2) kinase AK38_RS12055 ENOG4105RI1 glycoprotein receptor AK38_RS12060 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AK38_RS12065 ENOG4105DM4 PTS System AK38_RS12070 ENOG4108YRF PTS System AK38_RS12075 ENOG4108XCZ PTS System AK38_RS12080 ENOG4106R3P AraC family transcriptional regulator AK38_RS12090 ENOG4108M3P Membrane AK38_RS12160 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 AK38_RS12180 ENOG4105WSB biofilm stress and motility protein A AK38_RS12185 ENOG4105CSU acyl-Coa dehydrogenase AK38_RS12190 ENOG4105C2N RNA methyltransferase TrmH family group 3 AK38_RS12195 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) AK38_RS12215 ENOG4105EPW hflc protein AK38_RS12220 ENOG4107QJR hflk protein AK38_RS12225 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) AK38_RS12245 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase AK38_RS12250 ENOG4105K8N protein family UPF0079, ATPase AK38_RS12255 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) AK38_RS12260 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) AK38_RS12270 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) AK38_RS12290 ENOG4105EGS Mechanosensitive ion channel AK38_RS12320 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) AK38_RS12345 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein AK38_RS12350 ENOG4108ZVF (LipO)protein AK38_RS12375 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter AK38_RS12390 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) AK38_RS12395 ENOG4108RC0 Electron transport protein AK38_RS12400 ENOG4105BZ8 glutamate synthase AK38_RS12405 ENOG4108SIC Transcriptional regulator AK38_RS12475 ENOG4105C0A alcohol dehydrogenase AK38_RS12485 ENOG4108UUM single-stranded DNA-binding protein AK38_RS12490 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) AK38_RS12495 ENOG4105MSB protein, conserved in bacteria AK38_RS12500 ENOG4105CGF Aromatic amino acid aminotransferase AK38_RS12510 ENOG4105CDU Replicative dna helicase AK38_RS12515 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein AK38_RS12520 ENOG4105P4Z Phage shock protein G AK38_RS12525 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AK38_RS12530 ENOG4105MYN Zinc uptake regulation protein AK38_RS12540 ENOG41080IJ Diacylglycerol kinase AK38_RS12585 ENOG4108S1B Periplasmic chaperone protein AK38_RS12600 ENOG4108RS6 transposase AK38_RS12655 ENOG4105DAX Pfam:DUF2983 AK38_RS12675 ENOG4105D4P Coproporphyrinogen iii oxidase AK38_RS12680 ENOG41090JE Utilization Protein AK38_RS12690 ENOG4107ENK receptor AK38_RS12695 ENOG4106QJH hemin transport protein AK38_RS12700 ENOG4107R4I Periplasmic binding protein AK38_RS12705 ENOG4105EHG Permease protein AK38_RS12715 ENOG4105C28 cystathionine AK38_RS12720 ENOG4105C44 Serine transporter AK38_RS12725 ENOG4105EQ2 LysR family Transcriptional regulator AK38_RS12735 ENOG41066VF YeeE YedE family protein AK38_RS12740 ENOG4108IUF type iii secretion AK38_RS12745 ENOG4108TN6 type iii secretion AK38_RS12750 ENOG41083GP type iii secretion AK38_RS12755 ENOG4108HHI Type III secretion system protein AK38_RS12760 ENOG41063Q7 Type III secretion system protein AK38_RS12775 ENOG4108JIR Flagellum-specific ATP synthase AK38_RS12835 ENOG4105BZU Histidine kinase AK38_RS12840 ENOG4105WH1 Two component transcriptional regulator luxr family AK38_RS12845 ENOG4105CK2 sodium dicarboxylate symporter AK38_RS12855 ENOG41062QD Membrane AK38_RS12880 ENOG4108Z0R Transferase AK38_RS12895 ENOG4108WI1 Dna topoisomerase AK38_RS12905 ENOG4105C79 DNA protecting protein DprA AK38_RS12925 ENOG4105C1A potassium transporter peripheral membrane AK38_RS12935 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system AK38_RS12940 ENOG4105W1Y Transcriptional regulator AK38_RS12955 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) AK38_RS12975 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) AK38_RS12985 ENOG4105VPB 50S ribosomal protein L30 AK38_RS13030 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal AK38_RS13040 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) AK38_RS13045 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) AK38_RS13055 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) AK38_RS13065 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) AK38_RS13110 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) AK38_RS13135 ENOG4105WWK YheO domain protein AK38_RS13140 ENOG4108V1T peptidylprolyl cis-trans isomerase AK38_RS13150 ENOG4108YZY peptidylprolyl cis-trans isomerase AK38_RS13155 ENOG4105VKU nucleicacid-binding protein AK38_RS13175 ENOG4105K64 Glycosyl transferase, family 2 AK38_RS13185 ENOG4105E2B Taurine dioxygenase AK38_RS13190 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component AK38_RS13200 ENOG4106FTQ Taurine ABC transporter, periplasmic AK38_RS13210 ENOG4105DNZ Alpha Beta Hydrolase AK38_RS13220 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) AK38_RS13230 ENOG4108UKZ OsmC family AK38_RS13235 ENOG4107RYR Transcriptional regulator, Crp Fnr family AK38_RS13240 ENOG410613R integral membrane protein, YccS YhfK family AK38_RS13275 ENOG4105D7A ATP-binding protein AK38_RS13280 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AK38_RS13285 ENOG4105F8D glycoside hydrolase family 4 AK38_RS13290 ENOG41060NJ transcriptional regulator AK38_RS13305 ENOG4105DZC cytosine deaminase AK38_RS13310 ENOG4107QZF nitrite reductase NADPH large subunit AK38_RS13315 ENOG4105WZK nitrite reductase NADPH small subunit AK38_RS13320 ENOG4107V9H nitrite transporter AK38_RS13330 ENOG4105C31 Tryptophanyl-tRNA synthetase AK38_RS13335 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) AK38_RS13340 ENOG4105DJV ribulose-phosphate 3-epimerase AK38_RS13365 ENOG4105E4G Type IV pilus AK38_RS13395 ENOG4108JQC penicillin-binding protein 1A AK38_RS13400 ENOG4107RK2 ADP-ribose diphosphatase NudE AK38_RS13410 ENOG4105DQY intracellular growth attenuator AK38_RS13415 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 AK38_RS13420 ENOG4105VEJ Heat shock protein AK38_RS13435 ENOG4105E0F Histidine kinase AK38_RS13445 ENOG4108RRZ Transcription elongation factor GreB AK38_RS13450 ENOG4105BZM domain protein AK38_RS13460 ENOG4105XFK Ferrous iron transport protein A AK38_RS13465 ENOG4105CE1 Ferrous iron transport protein b AK38_RS13475 ENOG4105RID UPF0379 protein yhcN AK38_RS13485 ENOG4105MJ2 Competence protein AK38_RS13505 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AK38_RS13515 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) AK38_RS13525 ENOG4105E98 transcriptional regulator DeoR family AK38_RS13540 ENOG4105SYT Methylenetetrahydrofolate reductase AK38_RS13545 ENOG4105CFH Aspartokinase AK38_RS13565 ENOG4108Z12 YiaAB two helix domain-containing protein AK38_RS13575 ENOG4105C25 Primosomal protein n' AK38_RS13585 ENOG4105ETE Transcriptional regulator (LacI family AK38_RS13590 ENOG41063M6 Cell Division Protein AK38_RS13605 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase AK38_RS13630 ENOG4108MBX Secretion Protein AK38_RS13670 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) AK38_RS13685 ENOG4105DP0 ferredoxin-NADP reductase AK38_RS13690 ENOG4108VTS Membrane AK38_RS13695 ENOG4105EBK exported protein AK38_RS13705 ENOG4107F9Y LysR family transcriptional regulator AK38_RS13715 ENOG4105JSC dimethylmenaquinone methyltransferase AK38_RS13720 ENOG4107QPK )-transporter AK38_RS13730 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein AK38_RS13750 ENOG4105FMW periplasmic AK38_RS13755 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_RS13760 ENOG4105E0F Histidine kinase AK38_RS13765 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) AK38_RS13770 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) AK38_RS13775 ENOG4105D7W serine acetyltransferase AK38_RS13795 ENOG4105VW4 glutaredoxin 3 AK38_RS13800 ENOG4107YZP Rhodanese domain protein AK38_RS13810 ENOG41063SB peptidase AK38_RS13825 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) AK38_RS13835 ENOG4105XA0 heptosyltransferase ii AK38_RS13840 ENOG4105D16 lipopolysaccharide heptosyltransferase i AK38_RS13845 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase AK38_RS13880 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase AK38_RS13905 ENOG4105DSJ YicC domain protein AK38_RS13910 ENOG4105EN6 Membrane AK38_RS13930 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AK38_RS13935 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase AK38_RS13940 ENOG4105CB5 ATP-dependent DNA helicase recG AK38_RS13945 ENOG4105D6U Sodium Glutamate Symporter AK38_RS13950 ENOG4105C2W permease AK38_RS13955 ENOG4105JV1 AsmA family AK38_RS13960 ENOG4105SUU thioesterase domain AK38_RS13985 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 AK38_RS13990 ENOG4105CI3 gtp-binding protein typa AK38_RS14000 ENOG4105C5F glutamine synthetase AK38_RS14005 ENOG4105CUX Signal transduction histidine kinase AK38_RS14010 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AK38_RS14015 ENOG4105D4P Coproporphyrinogen iii oxidase AK38_RS14030 ENOG4108RS6 transposase AK38_RS14040 ENOG4105C2M dna polymerase I AK38_RS14045 ENOG4108Z33 Thiol disulfide Interchange Protein AK38_RS14050 ENOG4105E27 serine threonine protein kinase AK38_RS14055 ENOG4105PC1 Conserved Protein AK38_RS14065 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b AK38_RS14100 ENOG4107EJG GntR family transcriptional regulator AK38_RS14105 ENOG4105C0R drug resistance transporter emrb qaca subfamily AK38_RS14115 ENOG4108RVA ribokinase AK38_RS14145 ENOG4108VVK transcriptional Regulator, AsnC AK38_RS14150 ENOG4105QTB Flavodoxin AK38_RS14165 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation AK38_RS14220 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) AK38_RS14225 ENOG4105C8U phosphate abc transporter AK38_RS14230 ENOG4105E2Z phosphate ABC transporter (Permease AK38_RS14250 ENOG4106PMH Extracellular solute-binding protein family 3 AK38_RS14255 ENOG4105EAD ABC transporter AK38_RS14260 ENOG4105DRP amino acid AbC transporter AK38_RS14265 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 AK38_RS14270 ENOG4105C7N Xanthine uracil vitamin C permease AK38_RS14295 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins AK38_RS14315 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) AK38_RS14330 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) AK38_RS14335 ENOG410667J hydrolase AK38_RS14355 ENOG4105C7B Threonine dehydratase AK38_RS14370 ENOG4105R2A (LipO)protein AK38_RS14390 ENOG4105JKW Valine--pyruvate aminotransferase AK38_RS14400 ENOG4107T9C Alpha amylase catalytic region AK38_RS14415 ENOG4108ZG0 Ompa motb domain protein AK38_RS14425 ENOG4108R3E Dna-3-methyladenine glycosylase i AK38_RS14440 ENOG4106JH6 (LipO)protein AK38_RS14445 ENOG4105CTS PTS system mannitol-specific AK38_RS14455 ENOG4105E61 Mannitol repressor protein AK38_RS14460 ENOG4108YYI Protein of unknown function (DUF2810) AK38_RS14475 ENOG4105C8Q Methyl-accepting chemotaxis AK38_RS14480 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) AK38_RS14500 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein AK38_RS14505 ENOG4108MG3 formate dehydrogenase AK38_RS14520 ENOG4105EM7 Selenocysteine-specific translation elongation factor AK38_RS14525 ENOG4105EM7 Selenocysteine-specific translation elongation factor AK38_RS14575 ENOG4105MEV Acyl-transferase AK38_RS14580 ENOG4106EAR Fimbrial protein AK38_RS14590 ENOG4108TTM chaperone AK38_RS14600 ENOG4105CMG Carbohydrate kinase AK38_RS14610 ENOG4105DFW ABC transporter AK38_RS14620 ENOG4108HWW ABC transporter AK38_RS14625 ENOG4105T16 Transcriptional regulator (AraC family) AK38_RS14630 ENOG4105DFP Integrase AK38_RS14640 ENOG4105ZTC transcriptional activator, Ogr delta AK38_RS14670 ENOG4108IPW abc transporter atp-binding protein AK38_RS14675 ENOG4105CM4 permease protein AK38_RS14705 ENOG4105C6T cysteine synthase AK38_RS14715 ENOG4105C84 Histidine ammonia-lyase AK38_RS14720 ENOG4105C85 amino acid AK38_RS14730 ENOG4105DIJ Phosphoethanolamine transferase AK38_RS14735 ENOG4108KX4 response regulator AK38_RS14755 ENOG4105BZU Histidine kinase AK38_RS14760 ENOG4105CXY transporter AK38_RS14775 ENOG4105D5K Hemolysin activator protein AK38_RS14785 ENOG4105DEF Extracellular solute-binding protein, family 5 AK38_RS14790 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_RS14795 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_RS14800 ENOG4105C3U ABC transporter AK38_RS14805 ENOG4108JQ7 (ABC) transporter AK38_RS14810 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) AK38_RS14815 ENOG4105BZU Histidine kinase AK38_RS14820 ENOG4108PU9 oligogalacturonate-specific porin AK38_RS14840 ENOG4105CS0 peptidase AK38_RS14845 ENOG4107SS6 2-dehydro-3-deoxygluconokinase AK38_RS14850 ENOG4105VSH 4-oxalocrotonate tautomerase AK38_RS14855 ENOG4105CMB EAL domain-containing protein AK38_RS14860 ENOG41066T0 asmA family AK38_RS14865 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) AK38_RS14870 ENOG4107H3J ribonuclease AK38_RS14895 ENOG4105BZW Glycerate kinase AK38_RS14900 ENOG4107QQ0 gntp family AK38_RS14905 ENOG4107VHA regulatoR AK38_RS14910 ENOG4105DC8 reductase AK38_RS14915 ENOG4105D6S protein involved in catabolism of external DNA AK38_RS14920 ENOG4105DGW oligopeptidase A AK38_RS14940 ENOG4108M6U Universal stress protein A AK38_RS14960 ENOG4105CJ3 phosphate transporter AK38_RS14965 ENOG4105CBX hi0933 family AK38_RS14980 ENOG4105CNN ABC, transporter AK38_RS14985 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator AK38_RS14995 ENOG4105D2N Aldolase AK38_RS15015 ENOG4105C2I pirin domain protein AK38_RS15020 ENOG4105DIQ Transcriptional regulator AK38_RS15025 ENOG4105C6Z Gluconate AK38_RS15030 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family AK38_RS15050 ENOG41076UM multiple antibiotic resistance (MarC)-related protein AK38_RS15055 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AK38_RS15085 ENOG4108HRK Histidine kinase AK38_RS15110 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AK38_RS15115 ENOG4105C6V Glycerol-3-phosphate dehydrogenase AK38_RS15165 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase AK38_RS15185 ENOG4105X58 receptor AK38_RS15200 ENOG4107QZV Type I secretion membrane fusion protein AK38_RS15205 ENOG4105YHG TonB family AK38_RS15210 ENOG4107QN2 dihydrolipoyl dehydrogenase AK38_RS15215 ENOG4105EHV domain protein AK38_RS15220 ENOG4105C5Q Transcriptional regulator AK38_RS15235 ENOG4108Y73 Membrane AK38_RS15290 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator AK38_RS15295 ENOG4105C2J ABC transporter AK38_RS15300 ENOG4107R9N ABC transporter AK38_RS15305 ENOG41062B0 ABC transporter, permease AK38_RS15315 ENOG4108WFC UPF0438 protein yifE AK38_RS15320 ENOG4105C0P Mg chelatase subunit ChlI AK38_RS15330 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit AK38_RS15335 ENOG4105CM2 brancheD-chain amino acid aminotransferase AK38_RS15345 ENOG4105C7B Threonine dehydratase AK38_RS15380 ENOG4105EMY transcriptional regulator AK38_RS15420 ENOG4108VEV chaperone AK38_RS15430 ENOG4105CW0 outer membrane usher protein AK38_RS15435 ENOG4105GQR Chaperone AK38_RS15460 ENOG4105KQ5 peptidylprolyl cis-trans isomerase AK38_RS15470 ENOG4105C4R Atp-dependent dna helicase AK38_RS15495 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) AK38_RS15500 ENOG4105ESV Glycosyl transferase, family 4 AK38_RS15505 ENOG4105SFE lipopolysaccharide biosynthesis protein AK38_RS15510 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase AK38_RS15515 ENOG4108IJ1 Dehydrogenase AK38_RS15520 ENOG4105C1B dTDP-glucose 4-6-dehydratase AK38_RS15525 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) AK38_RS15530 ENOG4108WJ1 acetyltransferase AK38_RS15535 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AK38_RS15540 ENOG4105EGZ biosynthesis protein AK38_RS15560 ENOG4105C85 amino acid AK38_RS15590 ENOG410601J HemY protein AK38_RS15595 ENOG4105ECF c-methyltransferase AK38_RS15600 ENOG41076E6 Uroporphyrinogen-III Synthase AK38_RS15610 ENOG4107T0K Adenylate cyclase AK38_RS15620 ENOG4105S7Z (LipO)protein AK38_RS15630 ENOG4105CT0 Protein of unknown function, DUF484 AK38_RS15635 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) AK38_RS15640 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant AK38_RS15645 ENOG4105C4R Atp-dependent dna helicase AK38_RS15655 ENOG4105EQN UPF0261 protein AK38_RS15670 ENOG4105FR1 rard protein AK38_RS15675 ENOG4108VUY thioesterase Superfamily protein AK38_RS15680 ENOG4105HDD phospholipase AK38_RS15685 ENOG4105C9U ATP-dependent DNA helicase RecQ AK38_RS15690 ENOG4105CCF Lysine exporter protein (Lyse ygga) AK38_RS15695 ENOG410829K Lysine exporter protein (Lyse ygga) AK38_RS15700 ENOG4108EUD Lysophospholipase AK38_RS15705 ENOG4105DQF Hydrolase AK38_RS15715 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase AK38_RS15725 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A AK38_RS15735 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) AK38_RS15740 ENOG4108W1V Lipoprotein AK38_RS15745 ENOG4105EX9 Membrane AK38_RS15760 ENOG4107FS9 Membrane AK38_RS15775 ENOG4105MG3 Membrane AK38_RS15780 ENOG4106H78 methyltransferase AK38_RS15795 ENOG4105CAK Cell division ATP-binding protein ftsE AK38_RS15800 ENOG4105CRP Part of the ABC transporter FtsEX involved in AK38_RS15815 ENOG4108RS6 transposase AK38_RS15820 ENOG4105U59 -acetyltransferase AK38_RS15825 ENOG4105CP9 extracellular ligand-binding receptor AK38_RS15830 ENOG4105C32 Amino acid ABC transporter (Permease) AK38_RS15835 ENOG4105CF8 branched-chain amino acid ABC transporter, permease AK38_RS15840 ENOG4105C0Z ABC transporter AK38_RS15845 ENOG4108IV0 ABC, transporter AK38_RS15905 ENOG4107T6V glycerophosphoryl diester phosphodiesterase AK38_RS15910 ENOG4105RK9 auxin efflux carrier AK38_RS15915 ENOG4105EMK carboxylate amino acid amine transporter AK38_RS15920 ENOG4105DZ2 Transcriptional regulator AK38_RS15930 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) AK38_RS15935 ENOG4107SXA Phosphorylase AK38_RS15950 ENOG4108KF1 Membrane AK38_RS15955 ENOG4105CGY Dna recombination protein AK38_RS15965 ENOG4105JC1 sterol-binding domain protein AK38_RS15975 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) AK38_RS15985 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) AK38_RS16010 ENOG4105D52 delta-aminolevulinic acid dehydratase AK38_RS16015 ENOG4105MDZ Transcriptional activator rfaH AK38_RS16020 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) AK38_RS16025 ENOG4107QK7 reductase AK38_RS16045 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein AK38_RS16060 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) AK38_RS16065 ENOG4108RR8 protoporphyrinogen oxidase AK38_RS16095 ENOG4105D4A Cell wall formation (By similarity) AK38_RS16100 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase AK38_RS16150 ENOG4105PM1 preprotein translocase subunit SecE AK38_RS16155 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) AK38_RS16190 ENOG4108RS6 transposase AK38_RS16205 ENOG4105D41 biosynthesis protein thiH AK38_RS16210 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) AK38_RS16220 ENOG4105D06 uba thif-type nad fad binding protein AK38_RS16255 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) AK38_RS16260 ENOG4105R2J Conserved Protein AK38_RS16270 ENOG4108T8B Protein of unknown function (DUF1481) AK38_RS16275 ENOG4105C12 Phosphoribosylglycinamide synthetase AK38_RS16335 ENOG4107QP3 malate synthase g AK38_RS16340 ENOG4108I9X Isocitrate lyase AK38_RS16360 ENOG4105C3R Methionine synthase AK38_RS16375 ENOG4105CFH Aspartokinase AK38_RS16390 ENOG4105EG2 ABC transporter, permease AK38_RS16395 ENOG4105D56 permease protein AK38_RS16400 ENOG4107FKK extracellular solute-binding protein family 1 AK38_RS16420 ENOG4107W52 maltose operon periplasmic protein AK38_RS16430 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_RS16480 ENOG4105D4X repressor AK38_RS16485 ENOG4105C5Y PTS System AK38_RS16490 ENOG4105CG3 alpha amylase, catalytic region AK38_RS16495 ENOG4105NXH GreA GreB family elongation factor AK38_RS16500 ENOG4108XVM Cytochrome b(562) AK38_RS16510 ENOG4105CMS peptidase U62, modulator of DNA gyrase AK38_RS16520 ENOG4105UNR (Barnase) inhibitor AK38_RS16555 ENOG4105CR8 Transcriptional regulator AK38_RS16610 ENOG4105D1U peptidase U62 modulator of DNA gyrase AK38_RS16620 ENOG4105QD6 exported protein AK38_RS16625 ENOG4105C03 ribonuclease AK38_RS16630 ENOG4108Z03 MAF-like protein AK38_RS16635 ENOG4105VQ7 Rod shape-determining protein MreD AK38_RS16640 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) AK38_RS16650 ENOG41062P1 Diguanylate cyclase phosphodiesterase AK38_RS16655 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family AK38_RS16660 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) AK38_RS16675 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein AK38_RS16680 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase AK38_RS16685 ENOG4105RG0 Membrane AK38_RS16690 ENOG4108IA2 Sodium pantothenate symporter AK38_RS16700 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) AK38_RS16705 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) AK38_RS16720 ENOG4105CSH Transporter AK38_RS16725 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase AK38_RS16740 ENOG4108XTF Outer Membrane Lipoprotein AK38_RS16750 ENOG4105VEQ Cold shock protein AK38_RS16755 ENOG4105VEQ Cold shock protein AK38_RS16780 ENOG4105CYM Glutathione S-transferase AK38_RS16785 ENOG4105C2X Arabinose 5-phosphate isomerase AK38_RS16790 ENOG4105EF1 ribulokinase AK38_RS16800 ENOG4105CNN ABC, transporter AK38_RS16805 ENOG4105C2J ABC transporter AK38_RS16815 ENOG4105D1S lipid A biosynthesis AK38_RS16825 ENOG4105EEQ Na H antiporter AK38_RS16830 ENOG4105C7N Xanthine uracil vitamin C permease AK38_RS16845 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component AK38_RS16855 ENOG4105GVF (ABC) transporter AK38_RS16870 ENOG4108RVA ribokinase AK38_RS16875 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) AK38_RS16880 ENOG4105W4W Transcriptional regulator AK38_RS16885 ENOG4107TYG Oxidoreductase domain-containing protein AK38_RS16900 ENOG4105CNA YD repeat protein AK38_RS16910 ENOG4105CS6 Rhs element vgr protein AK38_RS16935 ENOG4105CNA YD repeat protein AK38_RS16950 ENOG4105CS6 Rhs element vgr protein AK38_RS16985 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS17030 ENOG4105KME endoribonuclease L-psp AK38_RS17045 ENOG41080Z8 PHOSPHOCARRIER protein AK38_RS17055 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN AK38_RS17065 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_RS17070 ENOG4108IUZ ABC transporter AK38_RS17075 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA AK38_RS17080 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) AK38_RS17085 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase AK38_RS17090 ENOG4105C2X Arabinose 5-phosphate isomerase AK38_RS17095 ENOG4105FEU K -dependent Na -Ca exchanger AK38_RS17100 ENOG4105DHJ ABC, transporter AK38_RS17105 ENOG4105CY3 ABC transporter, permease AK38_RS17110 ENOG4107PE3 Mammalian cell entry related domain protein AK38_RS17115 ENOG4105E3I toluene tolerance AK38_RS17120 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane AK38_RS17125 ENOG4105VFK BolA family AK38_RS17135 ENOG4105C0H protease AK38_RS17145 ENOG4105C0H protease AK38_RS17150 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III AK38_RS17155 ENOG4105D6Z AFG1 family ATPase AK38_RS17175 ENOG4107MKT Stringent starvation protein a AK38_RS17180 ENOG4105KB2 stringent starvation protein b AK38_RS17190 ENOG4105BZ8 glutamate synthase AK38_RS17195 ENOG4105CBC glutamate synthase AK38_RS17200 ENOG4105N5T Radical SAM Protein AK38_RS17210 ENOG4105BZU Histidine kinase AK38_RS17220 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain AK38_RS17230 ENOG4105W4M Transport-associated protein AK38_RS17250 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) AK38_RS17260 ENOG4108CNN domain protein AK38_RS17265 ENOG4105CWB LysR family transcriptional Regulator AK38_RS17285 ENOG4108MXZ Esterase AK38_RS17295 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) AK38_RS17320 ENOG4108RS6 transposase AK38_RS17330 ENOG4105FHY Opacity-associated protein A AK38_RS17335 ENOG4108V1T peptidylprolyl cis-trans isomerase AK38_RS17345 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic AK38_RS17350 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase AK38_RS17355 ENOG4108UUE Transcriptional regulator AK38_RS17360 ENOG41061GZ Protein of unknown function (DUF1107) AK38_RS17365 ENOG4105C37 (CBS) domain AK38_RS17375 ENOG4105CFU surface antigen AK38_RS17385 ENOG4108ZHD aig2 family AK38_RS17390 ENOG4105F0N pyrophosphate phospho-hydrolase AK38_RS17395 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 AK38_RS17400 ENOG4105DFU Cell wall formation (By similarity) AK38_RS17420 ENOG4105HVQ Regulatory factor of maltose metabolism AK38_RS17430 ENOG4105EAH synthase AK38_RS17445 ENOG4105QYV Membrane AK38_RS17475 ENOG4105HBR Rna-binding protein AK38_RS17485 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) AK38_RS17490 ENOG4105EEI dihydropteroate synthase AK38_RS17500 ENOG4105NTZ Preprotein translocase subunit SecG AK38_RS17520 ENOG4105CHV Transcription elongation factor NusA AK38_RS17565 ENOG4105C1J atp-dependent rna helicase AK38_RS17585 ENOG4105DEN Luciferase family AK38_RS17595 ENOG4105BZS acriflavin resistance protein AK38_RS17600 ENOG4105ENJ RND efflux system, outer membrane lipoprotein AK38_RS17625 ENOG4108YYD acetyltransferase AK38_RS17655 ENOG4105DRS transport system, permease AK38_RS17675 ENOG4105K4T epimerase AK38_RS17680 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein AK38_RS17685 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) AK38_RS17690 ENOG4105FD8 phosphonate metabolism protein PhnM AK38_RS17695 ENOG4105HRV phosphonate c-p lyase system protein phnl AK38_RS17700 ENOG4105ENV phosphonate C-P lyase system protein PhnK AK38_RS17705 ENOG4105FT8 Phosphonate metabolism AK38_RS17710 ENOG4105EKV Phosphonate metabolism protein AK38_RS17715 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH AK38_RS17730 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) AK38_RS17735 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase AK38_RS17740 ENOG4108JQ7 (ABC) transporter AK38_RS17745 ENOG4105C3U ABC transporter AK38_RS17750 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_RS17755 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_RS17765 ENOG4105XEP YhcH YjgK YiaL family protein AK38_RS17775 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) AK38_RS17780 ENOG4108MJ3 acetyltransferase AK38_RS17785 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) AK38_RS17790 ENOG4105MYG DNA polymerase iii, chi subunit AK38_RS17800 ENOG4108M8S permease YjgP YjgQ family protein AK38_RS17805 ENOG4108K5H permease YjgP YjgQ family protein AK38_RS17825 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) AK38_RS17870 ENOG4105D7Q type ii secretion system AK38_RS17875 ENOG4107QHF type ii secretion system protein e AK38_RS17880 ENOG4108ZUW Major pilin subunit AK38_RS17885 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase AK38_RS17890 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase AK38_RS17895 ENOG4106A72 regulatory protein AmpE AK38_RS17900 ENOG4105C85 amino acid AK38_RS17905 ENOG41073TP transcriptional regulator AK38_RS17910 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) AK38_RS17915 ENOG4107QSN dihydrolipoamide acetyltransferase AK38_RS17920 ENOG4107QN2 dihydrolipoyl dehydrogenase AK38_RS17930 ENOG4108RS6 transposase AK38_RS17935 ENOG4107QIJ Aconitate hydratase 2 AK38_RS17945 ENOG4105RPH Inner membrane protein YddG AK38_RS17960 ENOG4108ZRK uncharacterized protein yacC AK38_RS17965 ENOG4105E3B Multicopper oxidase AK38_RS17970 ENOG4108UGV hypoxanthine phosphoribosyltransferase AK38_RS17975 ENOG41077A9 carbonic anhydrase AK38_RS17980 ENOG4105DA5 (ABC) transporter AK38_RS17985 ENOG4105E3A (ABC) transporter AK38_RS17990 ENOG4107BJW polysaccharide deacetylase AK38_RS18010 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase AK38_RS18015 ENOG4105DJ0 Poly(A) Polymerase AK38_RS18020 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) AK38_RS18025 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters AK38_RS18035 ENOG4107XID 2'-5' rna ligase AK38_RS18040 ENOG4105CQ7 ATP-dependent helicase AK38_RS18045 ENOG4105BZ4 penicillin-binding protein AK38_RS18050 ENOG4105E0A ABC, transporter AK38_RS18055 ENOG4105J76 Periplasmic binding protein AK38_RS18060 ENOG4105S6R Iron-hydroxamate transporter permease subunit AK38_RS18080 ENOG4105EN6 Membrane AK38_RS18100 ENOG4105C0H protease AK38_RS18105 ENOG4105BZU Histidine kinase AK38_RS18110 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) AK38_RS18120 ENOG4105DXN mazG family AK38_RS18140 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) AK38_RS18145 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase AK38_RS18195 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) AK38_RS18200 ENOG4105N0Z inner membrane protein ygbE AK38_RS18235 ENOG4108K5P (LipO)protein AK38_RS18240 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) AK38_RS18255 ENOG4108YZG isomerase AK38_RS18260 ENOG4105CPQ Dehydrogenase AK38_RS18265 ENOG4105CHR reductase AK38_RS18270 ENOG4105CMT Dihydroxyacetone kinase AK38_RS18280 ENOG4105DKT Transcriptional regulator AK38_RS18305 ENOG4105E89 ABC transporter AK38_RS18310 ENOG4105CA0 peroxidase AK38_RS18320 ENOG4105D05 Receptor AK38_RS18335 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AK38_RS18345 ENOG4107GFK fumarate AK38_RS18350 ENOG4105CMG Carbohydrate kinase AK38_RS18355 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase AK38_RS18360 ENOG4105F5R ABC transporter AK38_RS18365 ENOG4105CNN ABC, transporter AK38_RS18370 ENOG4105C2J ABC transporter AK38_RS18375 ENOG4108RS6 transposase AK38_RS18385 ENOG4105E98 transcriptional regulator DeoR family AK38_RS18390 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase AK38_RS18395 ENOG4107QY8 reductase AK38_RS18400 ENOG4105QAX Iron-sulfur AK38_RS18405 ENOG4107KGK dmso reductase anchor subunit AK38_RS18410 ENOG4108NEM leader-binding protein dmsD AK38_RS18415 ENOG4105CPW cytochrome b561 AK38_RS18420 ENOG4108XVM Cytochrome b(562) AK38_RS18440 ENOG4105C2J ABC transporter AK38_RS18445 ENOG4105CNN ABC, transporter AK38_RS18450 ENOG4108HHA Transketolase AK38_RS18455 ENOG4108IUS Transketolase AK38_RS18460 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) AK38_RS18530 ENOG4107VXZ Hydrolase AK38_RS18535 ENOG4105W39 Membrane AK38_RS18540 ENOG4105D9M gamma-glutamylcysteine synthetase AK38_RS18555 ENOG4108RS6 transposase AK38_RS18570 ENOG4108JU6 CBS domain protein AK38_RS18575 ENOG4106KVJ cytochrome C assembly protein AK38_RS18580 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY AK38_RS18615 ENOG4108NE3 Salt-induced outer membrane protein AK38_RS18635 ENOG4108NEV two component transcriptional regulator, LytTR family AK38_RS18640 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) AK38_RS18645 ENOG4105EHE chorismate mutase- prephenate dehydrogenase AK38_RS18675 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA AK38_RS18680 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane AK38_RS18685 ENOG4105C34 Pseudouridine synthase AK38_RS18690 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase AK38_RS18695 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS18730 ENOG4105T42 (LipO)protein AK38_RS18735 ENOG4105JIM Phosphatidylserine synthase AK38_RS18740 ENOG4105CD5 CoA-binding domain protein AK38_RS18745 ENOG4106IUH DTW domain containing protein AK38_RS18750 ENOG4105K63 Thioredoxin AK38_RS18755 ENOG4105EIB trna rrna methyltransferase AK38_RS18760 ENOG4105C0R drug resistance transporter emrb qaca subfamily AK38_RS18765 ENOG4105CW7 secretion protein, HlyD family AK38_RS18770 ENOG4105NTK Transcriptional repressor Mpra AK38_RS18775 ENOG4105ZED uncharacterized protein ygaH AK38_RS18780 ENOG4108UMN azlc family AK38_RS18785 ENOG4105EQ0 Major Facilitator superfamily AK38_RS18825 ENOG4105E5Q amino acid AbC transporter AK38_RS18835 ENOG4105C5R Aminotransferase AK38_RS18850 ENOG4105C5R Aminotransferase AK38_RS18870 ENOG4106YJS accessory processing protein AK38_RS18880 ENOG4107QPN acyl-Coa dehydrogenase AK38_RS18890 ENOG4105E7A Glutamine amidotransferase AK38_RS18895 ENOG4105F7V ErfK ybiS ycfS ynhG family protein AK38_RS18905 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AK38_RS18910 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) AK38_RS18930 ENOG4105CJ2 (LipO)protein AK38_RS18950 ENOG4105CIN aminoacyl-histidine dipeptidase AK38_RS18960 ENOG4108KB2 LysR family Transcriptional regulator AK38_RS19010 ENOG4105F2W methyltransferase AK38_RS19045 ENOG4105DKQ ROK family AK38_RS19065 ENOG4105EYH Exonuclease AK38_RS19070 ENOG4107RH8 nuclease SbcCD subunit D AK38_RS19080 ENOG4105CK6 Two component transcriptional regulator (Winged helix family AK38_RS19085 ENOG4105BZU Histidine kinase AK38_RS19090 ENOG4105DJH phosphate AK38_RS19095 ENOG4105CWM branched-chain amino acid transport system II carrier protein AK38_RS19100 ENOG4105C85 amino acid AK38_RS19105 ENOG4107R28 alpha amylase, catalytic region AK38_RS19110 ENOG4105CHR reductase AK38_RS19130 ENOG4108RS6 transposase AK38_RS19135 ENOG4105D3R alkyl hydroperoxide reductase AK38_RS19155 ENOG4105VIE preprotein translocase, subunit YajC AK38_RS19160 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AK38_RS19165 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) AK38_RS19190 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) AK38_RS19205 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) AK38_RS19210 ENOG4108ZAI phosphatidylglycerophosphatase a AK38_RS19230 ENOG4105CTB Polyprenyl synthetase AK38_RS19250 ENOG4107S0N DJ-1 family AK38_RS19255 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) AK38_RS19265 ENOG4107RDB Major Facilitator AK38_RS19275 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) AK38_RS19280 ENOG4105CCU oxidase (Subunit III) AK38_RS19285 ENOG4105BZ9 Cytochrome C oxidase, subunit I AK38_RS19290 ENOG4105E2S oxidase) subunit II AK38_RS19295 ENOG4108NFH Sugar hydrolase AK38_RS19300 ENOG4105EYM Major Facilitator superfamily AK38_RS19305 ENOG4105IEY (LipO)protein AK38_RS19310 ENOG4105M85 Bola protein AK38_RS19335 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) AK38_RS19340 ENOG4105K70 DNA-binding protein AK38_RS19345 ENOG4105EIN peptidylprolyl cis-trans isomerase AK38_RS19350 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein AK38_RS19355 ENOG4108TGP Thioesterase superfamily protein AK38_RS19365 ENOG4108NFA extracellular solute-binding protein AK38_RS19375 ENOG4105C6T cysteine synthase AK38_RS19380 ENOG4108XM1 transcriptional regulator AsnC family AK38_RS19385 ENOG4105BZ1 (ABC) transporter AK38_RS19390 ENOG4105BZ1 (ABC) transporter AK38_RS19395 ENOG4108YZA Nitrogen regulatory protein pii AK38_RS19400 ENOG4105BZU Histidine kinase AK38_RS19405 ENOG4105C29 acyl-CoA thioesterase AK38_RS19410 ENOG4108MNP Glycoprotein polysaccharide metabolism AK38_RS19415 ENOG41080UX Methyltransferase AK38_RS19425 ENOG4105KF5 hemolysin expression-modulating protein AK38_RS19430 ENOG4108UKR Biofilm formation regulator YbaJ AK38_RS19440 ENOG4105YK5 50S ribosomal protein L36 AK38_RS19450 ENOG4105BZS acriflavin resistance protein AK38_RS19455 ENOG4105C1P efflux transporter, rnd family, mfp subunit AK38_RS19460 ENOG4107XI7 Tetr family transcriptional regulator AK38_RS19465 ENOG41090EX DsrE family AK38_RS19470 ENOG4105EGS Mechanosensitive ion channel AK38_RS19475 ENOG4106428 Protein of unknown function (DUF2496) AK38_RS19505 ENOG4107QMP dna polymerase iii subunits gamma and tau AK38_RS19535 ENOG4108EX3 reductase AK38_RS19540 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase AK38_RS19545 ENOG4105FAW cDP-glucose 4,6-dehydratase AK38_RS19550 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase AK38_RS19555 ENOG4108SMP Nad-dependent epimerase dehydratase AK38_RS19585 ENOG4108TJN glycosyl transferase group 1 AK38_RS19600 ENOG4105CJT Mannose-1-phosphate guanylyltransferase AK38_RS19615 ENOG4108QY5 Ferric enterobactin transport protein AK38_RS19620 ENOG4107RE1 Inosine-guanosine kinase AK38_RS19625 ENOG4105CKD glutathione-regulated potassium-efflux system protein AK38_RS19630 ENOG4105EU0 Major facilitator Superfamily AK38_RS19655 ENOG4108Z66 YbaK ebsC protein AK38_RS19660 ENOG4105MBR gumn family AK38_RS19665 ENOG4105C59 p-type ATPase AK38_RS19670 ENOG4108Z6Z Transcriptional regulator AK38_RS19675 ENOG4105G5H Membrane AK38_RS19680 ENOG4107QX8 SPFH domain, Band 7 family protein AK38_RS19685 ENOG4107QR8 Thioredoxin AK38_RS19690 ENOG4105E1F short-chain dehydrogenase reductase AK38_RS19695 ENOG4108UJV acyl-CoA thioesterase i AK38_RS19700 ENOG4108I0Y (ABC) transporter AK38_RS19705 ENOG4105CV6 ABC transporter, permease AK38_RS19710 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit AK38_RS19715 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) AK38_RS19725 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) AK38_RS19740 ENOG4108RS6 transposase AK38_RS19750 ENOG4105K89 arsenate reductase AK38_RS19755 ENOG4105ERG peptidase m48, ste24p AK38_RS19760 ENOG4105C02 permease AK38_RS19780 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen AK38_RS19785 ENOG4105RH4 Glycine cleavage system transcriptional repressor AK38_RS19795 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AK38_RS19805 ENOG4108RS6 transposase AK38_RS19815 ENOG4105CGZ zinc metallopeptidase AK38_RS19845 ENOG4105KUZ arsenate reductase AK38_RS19855 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC AK38_RS19860 ENOG4107Z33 ABC transporter, permease AK38_RS19865 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_RS19870 ENOG4105ENH Sulfatase AK38_RS19875 ENOG4105C4X radical SAM domain protein AK38_RS19880 ENOG4105S2T inner membrane protein YbcI AK38_RS19890 ENOG4105BZS acriflavin resistance protein AK38_RS19900 ENOG4105WH1 Two component transcriptional regulator luxr family AK38_RS19905 ENOG4108ZNS ferredoxin-type protein NapF AK38_RS19910 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase AK38_RS19920 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) AK38_RS19925 ENOG4105CUW cytochrome C-TYPE protein AK38_RS19935 ENOG4105C6K Malic enzyme AK38_RS19970 ENOG4105H4F exported protein AK38_RS19975 ENOG4105E7K (LipO)protein AK38_RS19980 ENOG4105EZR dyp-type peroxidase family protein AK38_RS20005 ENOG4108R66 Conserved Protein AK38_RS20015 ENOG4105QEK Transcriptional regulator AK38_RS20025 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein AK38_RS20030 ENOG4108I5D sulfate abc transporter AK38_RS20035 ENOG4105ECW sulfate abc transporter AK38_RS20040 ENOG4108IJ6 ABC transporter AK38_RS20045 ENOG4105C6T cysteine synthase AK38_RS20055 ENOG4105DPZ Two component transcriptional regulator (Winged helix family AK38_RS20060 ENOG41062D9 Histidine kinase AK38_RS20070 ENOG4105C87 Aminotransferase class I and II AK38_RS20080 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) AK38_RS20090 ENOG4105E1V na solute symporter AK38_RS20105 ENOG4105DJY efflux transporter, rnd family, mfp subunit AK38_RS20110 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_RS20115 ENOG4105E0F Histidine kinase AK38_RS20130 ENOG4105C5Y PTS System AK38_RS20135 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) AK38_RS20145 ENOG4105C6T cysteine synthase AK38_RS20150 ENOG4105EXN Sulfate transport protein CysZ AK38_RS20165 ENOG4105VRT cytoplasmic protein AK38_RS20190 ENOG4108RS6 transposase AK38_RS20230 ENOG4105D9N nucleoside AK38_RS20245 ENOG4105CPC Aldo Keto reductase AK38_RS20250 ENOG4105C5Q Transcriptional regulator AK38_RS20265 ENOG41072TH Protein of unknown function (DUF1479) AK38_RS20270 ENOG4105CHM Aminotransferase AK38_RS20275 ENOG4108VKM cytochrome b561 AK38_RS20285 ENOG4106B0W Curli production assembly transport component CsgG AK38_RS20295 ENOG4107Y60 (LipO)protein AK38_RS20305 ENOG4108NEM leader-binding protein dmsD AK38_RS20310 ENOG4107KGK dmso reductase anchor subunit AK38_RS20315 ENOG4105QAX Iron-sulfur AK38_RS20320 ENOG4107QY8 reductase AK38_RS20330 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_RS20355 ENOG4105CVE Lytic murein transglycosylase AK38_RS20405 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit AK38_RS20415 ENOG4105GQR Chaperone AK38_RS20420 ENOG4105CW0 outer membrane usher protein AK38_RS20430 ENOG4105CW0 outer membrane usher protein AK38_RS20480 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) AK38_RS20495 ENOG4108RS6 transposase AK38_RS20500 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding AK38_RS20505 ENOG4106G6Q Transcriptional regulator AK38_RS20515 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB AK38_RS20520 ENOG4108Z6B deaminase AK38_RS20555 ENOG4107WP9 Histidine kinase AK38_RS20560 ENOG4108SKK alpha helix protein AK38_RS20565 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family AK38_RS20570 ENOG4105C4K Nad synthetase AK38_RS20575 ENOG4108YZA Nitrogen regulatory protein pii AK38_RS20590 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) AK38_RS20610 ENOG4105D8G Major Facilitator superfamily AK38_RS20615 ENOG4108MN2 Stationary phase inducible protein CsiE AK38_RS20620 ENOG41065CD Exported protein AK38_RS20625 ENOG4105D7X high-affinity nickel-transporter AK38_RS20630 ENOG4108RS6 transposase AK38_RS20635 ENOG4105ECY inositol monophosphatase AK38_RS20650 ENOG4105C3J Cysteine desulfurase AK38_RS20655 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins AK38_RS20670 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB AK38_RS20675 ENOG4108ZIT Ferredoxin, 2FE-2S AK38_RS20680 ENOG4105WVQ Fe-S assembly protein IscX AK38_RS20690 ENOG4105YYA enhanced serine sensitivity protein SseB AK38_RS20700 ENOG4108MGN ATP-binding component of a transport system AK38_RS20705 ENOG4108MGN ATP-binding component of a transport system AK38_RS20750 ENOG4105N21 Membrane AK38_RS20755 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) AK38_RS20770 ENOG4105VPD cellular component movement AK38_RS20780 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) AK38_RS20805 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_RS20850 ENOG4105DWF phosphomethylpyrimidine kinase AK38_RS20860 ENOG4108ZGU inhibitor of vertebrate lysozyme AK38_RS20870 ENOG4105CFP Peptidase U32 AK38_RS20875 ENOG4105KWI UPF0339 protein AK38_RS20880 ENOG4105E3W Two component transcriptional regulator (Winged helix family AK38_RS20915 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) AK38_RS20925 ENOG4108JPW Aminotransferase AK38_RS20935 ENOG4105F38 ABC transporter, permease AK38_RS20940 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component AK38_RS20945 ENOG4105R8A Heat shock protein AK38_RS20950 ENOG4105CJW magnesium transporter AK38_RS20960 ENOG4105C9X ppx gppa phosphatase AK38_RS20965 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) AK38_RS20970 ENOG4105C8U phosphate abc transporter AK38_RS20975 ENOG4105E2Z phosphate ABC transporter (Permease AK38_RS20995 ENOG4108MK9 spermidine N(1)-acetyltransferase AK38_RS21000 ENOG4108V3E phosphoribosylglycinamide formyltransferase AK38_RS21015 ENOG4108RS6 transposase AK38_RS21020 ENOG4105WQ3 Rna-binding protein AK38_RS21070 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase AK38_RS21075 ENOG4108HPI phosphatidate Cytidylyltransferase AK38_RS21085 ENOG4105E8V Alpha Beta Hydrolase Fold protein AK38_RS21090 ENOG41077RS Phosphatase AK38_RS21115 ENOG4105EQ2 LysR family Transcriptional regulator AK38_RS21120 ENOG4107SET aldo keto reductase AK38_RS21190 ENOG4108WC9 type VI secretion system effector, hcp1 family AK38_RS21215 ENOG4105HVQ Regulatory factor of maltose metabolism AK38_RS21230 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC AK38_RS21235 ENOG4105PTV Nudix Hydrolase AK38_RS21240 ENOG4108RE9 Phosphodiesterase AK38_RS21250 ENOG4105ECP epimerase AK38_RS21255 ENOG4108JEH abc transporter atp-binding protein AK38_RS21260 ENOG4106YG3 ABC transporter AK38_RS21265 ENOG4105DSP amino acid AbC transporter AK38_RS21270 ENOG4105E89 ABC transporter AK38_RS21275 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase AK38_RS21280 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase AK38_RS21285 ENOG4105E96 Colicin v production protein AK38_RS21290 ENOG4108S3P Sporulation domain protein AK38_RS21295 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase AK38_RS21305 ENOG4105DQR SNARE associated Golgi AK38_RS21315 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) AK38_RS21320 ENOG4108RS6 transposase AK38_RS21340 ENOG410631K Membrane AK38_RS21345 ENOG4106WZ1 flagella biosynthesis regulator AK38_RS21360 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) AK38_RS21370 ENOG4105MH2 YfcL protein AK38_RS21375 ENOG4108BPE -transporting atpase AK38_RS21380 ENOG4105EJ9 Membrane AK38_RS21385 ENOG4105HPZ Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity) AK38_RS21395 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) AK38_RS21405 ENOG4108BY2 phosphohistidine phosphatase AK38_RS21420 ENOG4105KZW UPF0381 protein AK38_RS21425 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation AK38_RS21430 ENOG410903C (LipO)protein AK38_RS21435 ENOG4105KWW Biogenesis protein AK38_RS21440 ENOG4105KWW Biogenesis protein AK38_RS21445 ENOG4107QX9 Thiol disulfide interChange protein AK38_RS21450 ENOG4105DA4 cytochrome c-type biogenesis protein AK38_RS21460 ENOG4105X3C heme exporter protein AK38_RS21465 ENOG41060IM Heme exporter protein AK38_RS21470 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) AK38_RS21490 ENOG4108V0P LemA family AK38_RS21500 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA AK38_RS21530 ENOG4105CS6 Rhs element vgr protein AK38_RS21570 ENOG4105C3F Signal peptidase i AK38_RS21585 ENOG4105WMJ Positive regulator of sigma E, RseC MucC AK38_RS21590 ENOG4105VQK sigma E regulatory protein, MucB RseB AK38_RS21605 ENOG4108IYU L-aspartate oxidase AK38_RS21615 ENOG4105C1J atp-dependent rna helicase AK38_RS21665 ENOG4107R7A Allophanate hydrolase subunit 2 AK38_RS21675 ENOG4107QNR UPF0135 protein AK38_RS21680 ENOG4107RF4 Phosphodiesterase AK38_RS21685 ENOG4105CVP deoxyribo-dipyrimidine photolyase AK38_RS21690 ENOG4107SEY Conserved Protein AK38_RS21695 ENOG4105XIQ Protein of unknown function (DUF2517) AK38_RS21725 ENOG4105C08 Histidine kinase AK38_RS21730 ENOG4105EEX Two component transcriptional regulator (Winged helix family AK38_RS21750 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 AK38_RS21775 ENOG4105EZV Transcriptional regulator AK38_RS21780 ENOG4105VCP PTS System AK38_RS21785 ENOG4105CK1 PTS System AK38_RS21790 ENOG4105VZJ PTS System AK38_RS21800 ENOG41085Q9 Protein CrcB homolog AK38_RS21810 ENOG4107SVH Potassium channel protein AK38_RS21820 ENOG4105XXV Acid-resistance protein AK38_RS21840 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) AK38_RS21865 ENOG4108YZ9 Urea amidohydrolase subunit gamma AK38_RS21870 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) AK38_RS21875 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) AK38_RS21880 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component AK38_RS21885 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component AK38_RS21890 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein AK38_RS21895 ENOG4105VEQ Cold shock protein AK38_RS21910 ENOG4108SAJ Protein of unknown function (DUF1198) AK38_RS21915 ENOG4108WMJ Protein of unknown function (DUF2002) AK38_RS21940 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) AK38_RS21945 ENOG4108IJ7 Glycine betaine AK38_RS21950 ENOG4108HQS Glycine betaine AK38_RS21955 ENOG4105GIJ Glycine betaine AK38_RS22005 ENOG4105EV9 Alpha Beta Hydrolase AK38_RS22015 ENOG4105NNH LexA regulated protein AK38_RS22020 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) AK38_RS22025 ENOG41090R7 Ferric uptake AK38_RS22045 ENOG4108RS6 transposase AK38_RS22050 ENOG4105CI1 PTS System AK38_RS22060 ENOG4105CE4 GlcNAc 6-P deacetylase AK38_RS22065 ENOG4105E2R ROK family AK38_RS22070 ENOG4105D4U had-superfamily hydrolase, subfamily iia AK38_RS22075 ENOG4105CAQ asparagine synthetase AK38_RS22110 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family AK38_RS22115 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) AK38_RS22120 ENOG4105C9A Phoh family AK38_RS22130 ENOG4108JU5 Magnesium and cobalt efflux protein AK38_RS22135 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) AK38_RS22140 ENOG4107RP9 extracellular solute-binding protein, family 3 AK38_RS22145 ENOG4105EAD ABC transporter AK38_RS22150 ENOG4105DRP amino acid AbC transporter AK38_RS22155 ENOG4105CDA abc transporter atp-binding protein AK38_RS22160 ENOG4107PAI alpha helical protein AK38_RS22175 ENOG4105DJF DNA polymerase III, delta' subunit AK38_RS22185 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) AK38_RS22665 ENOG4105DQ5 transport system permease protein AK38_RS22670 ENOG4105EHG Permease protein AK38_RS22920 ENOG4105CKT filamentous hemagglutinin AK38_RS23195 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) AK38_RS23375 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) AK38_RS23550 ENOG4108KU3 Integrase AK38_RS23935 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG AK38_RS23940 ENOG4107RJJ Transcriptional regulator AK38_RS24325 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) AK38_RS24330 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) AK38_RS24660 ENOG4106NZI LysR family Transcriptional regulator AK38_RS24665 ENOG4108JJA ABC, transporter AK38_RS24680 ENOG4105GMB type VI secretion system effector, hcp1 family