locus-tag	class	description
YPD8_RS00005	COG0716	FMN binding
YPD8_RS00010	COG1522	sequence-specific DNA binding
YPD8_RS00040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPD8_RS00050	COG0477	Major facilitator Superfamily
YPD8_RS00055	COG2186	Transcriptional regulator
YPD8_RS00090	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPD8_RS00100	COG3084	Protein conserved in bacteria
YPD8_RS00105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPD8_RS00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPD8_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPD8_RS00150	COG3852	Histidine kinase
YPD8_RS00155	COG0174	glutamine synthetase
YPD8_RS00170	COG1011	Hydrolase
YPD8_RS00195	COG0456	acetyltransferase
YPD8_RS00200	COG2982	Protein involved in outer membrane biogenesis
YPD8_RS00205	COG2233	PERMEase
YPD8_RS00210	COG0786	glutamate:sodium symporter activity
YPD8_RS00215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPD8_RS00220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPD8_RS00225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPD8_RS00245	COG2860	membrane
YPD8_RS00250	COG1561	YicC-like family, N-terminal region
YPD8_RS00310	COG1519	Transferase
YPD8_RS00315	COG0859	PFAM glycosyl transferase family 9
YPD8_RS00320	COG0859	PFAM glycosyl transferase family 9
YPD8_RS00330	COG0156	8-amino-7-oxononanoate synthase activity
YPD8_RS00345	COG4942	peptidase
YPD8_RS00355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPD8_RS00360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPD8_RS00380	COG1045	serine acetyltransferase
YPD8_RS00385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPD8_RS00390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPD8_RS00390	COG2169	Transcriptional regulator
YPD8_RS00395	COG2205	protein histidine kinase activity
YPD8_RS00400	COG0745	RESPONSE REGULATOR receiver
YPD8_RS00405	COG3678	ATP-independent chaperone mediated protein folding
YPD8_RS00425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPD8_RS00435	COG0471	metal ion transport
YPD8_RS00440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPD8_RS00445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPD8_RS00450	COG0583	DNA-binding transcription factor activity
YPD8_RS00465	COG3152	Membrane
YPD8_RS00475	COG1494	fructose-1,6-bisphosphatase
YPD8_RS00480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPD8_RS00485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPD8_RS00535	COG1575	Belongs to the MenA family. Type 1 subfamily
YPD8_RS00550	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPD8_RS00555	COG1609	Transcriptional regulator
YPD8_RS00565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPD8_RS00575	COG4682	membrane
YPD8_RS00595	COG0527	aspartate kinase activity
YPD8_RS00595	COG0460	homoserine dehydrogenase
YPD8_RS00605	COG2801	Transposase and inactivated derivatives
YPD8_RS00615	COG1349	DNA-binding transcription factor activity
YPD8_RS00625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPD8_RS00650	COG0058	SHG alpha-glucan phosphorylase activity
YPD8_RS00655	COG0058	SHG alpha-glucan phosphorylase activity
YPD8_RS00660	COG1640	4-alpha-glucanotransferase
YPD8_RS00695	COG1918	ferrous iron import across plasma membrane
YPD8_RS00710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPD8_RS00735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPD8_RS00740	COG1011	Hydrolase
YPD8_RS00755	COG0494	nUDIX hydrolase
YPD8_RS00790	COG4796	Type ii and iii secretion system protein
YPD8_RS00815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPD8_RS00820	COG0546	phosphoglycolate phosphatase activity
YPD8_RS00825	COG0180	Tryptophanyl-tRNA synthetase
YPD8_RS00845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPD8_RS00850	COG0402	S-adenosylhomocysteine deaminase activity
YPD8_RS00875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPD8_RS00880	COG0433	COG0433 Predicted ATPase
YPD8_RS00895	COG1289	transmembrane transporter activity
YPD8_RS00905	COG1765	OsmC-like protein
YPD8_RS00915	COG3954	Phosphoribulokinase
YPD8_RS00925	COG0429	hydrolase of the alpha beta-hydrolase fold
YPD8_RS00935	COG4521	taurine ABC transporter
YPD8_RS00950	COG2175	clavaminate synthase activity
YPD8_RS00960	COG1216	Glycosyl transferase, family 2
YPD8_RS00980	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPD8_RS00985	COG1047	Peptidyl-prolyl cis-trans
YPD8_RS00995	COG0545	Peptidyl-prolyl cis-trans isomerase
YPD8_RS01000	COG2964	Protein conserved in bacteria
YPD8_RS01020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPD8_RS01025	COG0049	tRNA binding
YPD8_RS01055	COG0051	transcription antitermination factor activity, RNA binding
YPD8_RS01070	COG0089	rRNA binding
YPD8_RS01080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPD8_RS01090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPD8_RS01105	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPD8_RS01110	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPD8_RS01150	COG1841	ribosomal large subunit assembly
YPD8_RS01160	COG0201	protein transport
YPD8_RS01165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPD8_RS01180	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPD8_RS01195	COG0789	Transcriptional regulator
YPD8_RS01200	COG3036	rescue of stalled ribosome
YPD8_RS01230	COG0758	DNA mediated transformation
YPD8_RS01240	COG0551	DNA topoisomerase type I activity
YPD8_RS01255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPD8_RS01280	COG3162	membrane
YPD8_RS01290	COG1301	dicarboxylic acid transport
YPD8_RS01400	COG2391	methyltransferase activity
YPD8_RS01405	COG0425	Belongs to the sulfur carrier protein TusA family
YPD8_RS01410	COG0583	DNA-binding transcription factor activity
YPD8_RS01415	COG0814	amino acid
YPD8_RS01420	COG0626	cystathionine gamma-synthase activity
YPD8_RS01430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPD8_RS01435	COG4558	Periplasmic binding protein
YPD8_RS01440	COG3720	iron ion transport
YPD8_RS01445	COG4771	TonB-dependent receptor
YPD8_RS01450	COG0702	epimerase
YPD8_RS01455	COG3721	Heme iron utilization protein
YPD8_RS01480	COG1358	cellular component organization or biogenesis
YPD8_RS01540	COG3121	Chaperone
YPD8_RS01585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPD8_RS01595	COG0735	belongs to the Fur family
YPD8_RS01600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPD8_RS01625	COG1448	Aminotransferase
YPD8_RS01630	COG2315	Protein conserved in bacteria
YPD8_RS01635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPD8_RS01640	COG0629	single-stranded DNA binding
YPD8_RS01650	COG1454	alcohol dehydrogenase
YPD8_RS01720	COG1309	transcriptional regulator
YPD8_RS01725	COG0493	'glutamate synthase
YPD8_RS01725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPD8_RS01730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPD8_RS01735	COG3383	formate dehydrogenase (NAD+) activity
YPD8_RS01750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPD8_RS01795	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPD8_RS01805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPD8_RS01810	COG1053	succinate dehydrogenase
YPD8_RS01825	COG3264	Mechanosensitive ion channel
YPD8_RS01825	COG1511	domain protein
YPD8_RS01845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPD8_RS01865	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPD8_RS01875	COG0802	atpase or kinase
YPD8_RS01880	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPD8_RS01900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPD8_RS01905	COG0330	HflC and HflK could
YPD8_RS01910	COG0330	HflC and HflK could
YPD8_RS01915	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPD8_RS01930	COG0557	exoribonuclease II activity
YPD8_RS01935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPD8_RS01940	COG1960	acyl-CoA dehydrogenase activity
YPD8_RS01945	COG3650	response to hydrogen peroxide
YPD8_RS01965	COG1401	restriction endodeoxyribonuclease activity
YPD8_RS01980	COG2963	transposase activity
YPD8_RS02035	COG4269	membrane
YPD8_RS02045	COG2207	Transcriptional regulator
YPD8_RS02050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPD8_RS02055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPD8_RS02060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPD8_RS02065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS02065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPD8_RS02065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS02115	COG1070	Carbohydrate kinase
YPD8_RS02120	COG0859	PFAM glycosyl transferase family 9
YPD8_RS02140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPD8_RS02145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPD8_RS02190	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPD8_RS02195	COG0456	acetyltransferase
YPD8_RS02205	COG2823	Periplasmic or secreted lipoprotein
YPD8_RS02215	COG4667	esterase of the alpha-beta hydrolase superfamily
YPD8_RS02220	COG0084	hydrolase, TatD family'
YPD8_RS02225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPD8_RS02255	COG3726	membrane protein affecting hemolysin expression
YPD8_RS02260	COG0560	Phosphoserine phosphatase
YPD8_RS02285	COG2885	chlorophyll binding
YPD8_RS02290	COG2199	diguanylate cyclase activity
YPD8_RS02305	COG0741	lytic transglycosylase activity
YPD8_RS02310	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPD8_RS02325	COG3708	Transcriptional regulator
YPD8_RS02325	COG2207	Transcriptional regulator
YPD8_RS02330	COG3045	CreA protein
YPD8_RS02335	COG0745	RESPONSE REGULATOR receiver
YPD8_RS02365	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPD8_RS02380	COG1584	GPR1 FUN34 yaaH family protein
YPD8_RS02400	COG0583	DNA-binding transcription factor activity
YPD8_RS02430	COG1047	Peptidyl-prolyl cis-trans
YPD8_RS02465	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPD8_RS02470	COG1280	lysine exporter protein (LysE YggA)
YPD8_RS02475	COG2966	Psort location CytoplasmicMembrane, score
YPD8_RS02485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPD8_RS02540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPD8_RS02545	COG0564	pseudouridine synthase activity
YPD8_RS02635	COG2885	chlorophyll binding
YPD8_RS02635	COG3047	cAMP biosynthetic process
YPD8_RS02655	COG0417	DNA replication proofreading
YPD8_RS02660	COG0586	Pfam SNARE associated Golgi protein
YPD8_RS02665	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
YPD8_RS02670	COG1178	ABC-type Fe3 transport system permease component
YPD8_RS02675	COG4143	(ABC) transporter
YPD8_RS02695	COG2814	Major facilitator Superfamily
YPD8_RS02710	COG2814	Major facilitator Superfamily
YPD8_RS02725	COG0473	3-isopropylmalate dehydrogenase activity
YPD8_RS02755	COG1022	Amp-dependent synthetase and ligase
YPD8_RS02765	COG0028	Belongs to the TPP enzyme family
YPD8_RS02785	COG1609	Transcriptional regulator
YPD8_RS02805	COG3116	cell division
YPD8_RS02810	COG0768	penicillin binding
YPD8_RS02820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPD8_RS02835	COG0772	Belongs to the SEDS family
YPD8_RS02855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPD8_RS02860	COG0849	cell division
YPD8_RS02865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPD8_RS02890	COG0494	nUDIX hydrolase
YPD8_RS02905	COG0435	Glutathione S-transferase
YPD8_RS02910	COG2259	Doxx family
YPD8_RS02920	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPD8_RS02925	COG4575	ribosome binding
YPD8_RS02945	COG0586	Pfam SNARE associated Golgi protein
YPD8_RS02960	COG2271	Major facilitator Superfamily
YPD8_RS02980	COG2721	sulfolactate sulfo-lyase activity
YPD8_RS03005	COG0673	inositol 2-dehydrogenase activity
YPD8_RS03010	COG1451	nucleotide metabolic process
YPD8_RS03025	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPD8_RS03025	COG1902	pentaerythritol trinitrate reductase activity
YPD8_RS03030	COG3247	response to pH
YPD8_RS03050	COG4245	von Willebrand factor, type A
YPD8_RS03065	COG4245	von Willebrand factor, type A
YPD8_RS03070	COG2831	hemolysin activation secretion protein
YPD8_RS03075	COG3210	domain, Protein
YPD8_RS03100	COG3210	domain, Protein
YPD8_RS03105	COG3210	domain, Protein
YPD8_RS03125	COG3842	ATPase activity
YPD8_RS03130	COG3459	Glycosyltransferase 36 associated
YPD8_RS03135	COG1609	Transcriptional regulator
YPD8_RS03140	COG2182	Extracellular solute-binding protein
YPD8_RS03150	COG0395	ABC-type sugar transport system, permease component
YPD8_RS03170	COG1289	transmembrane transporter activity
YPD8_RS03195	COG0436	Aminotransferase
YPD8_RS03215	COG0251	oxidation-reduction process
YPD8_RS03310	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YPD8_RS03325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPD8_RS03340	COG4991	sh3 domain protein
YPD8_RS03360	COG0531	amino acid
YPD8_RS03380	COG3384	dioxygenase
YPD8_RS03385	COG0754	glutathionylspermidine amidase activity
YPD8_RS03400	COG1538	Outer membrane efflux protein
YPD8_RS03405	COG0494	nUDIX hydrolase
YPD8_RS03410	COG3151	Protein conserved in bacteria
YPD8_RS03415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPD8_RS03420	COG3150	esterase
YPD8_RS03430	COG0583	DNA-binding transcription factor activity
YPD8_RS03435	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPD8_RS03445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPD8_RS03455	COG2132	Multicopper oxidase
YPD8_RS03465	COG0656	L-ascorbic acid biosynthetic process
YPD8_RS03475	COG1979	alcohol dehydrogenase
YPD8_RS03480	COG2207	Transcriptional regulator
YPD8_RS03485	COG0586	Pfam SNARE associated Golgi protein
YPD8_RS03490	COG0626	cystathionine gamma-synthase activity
YPD8_RS03495	COG0811	peptide transport
YPD8_RS03500	COG0848	biopolymer transport protein
YPD8_RS03550	COG4964	Belongs to the GSP D family
YPD8_RS03555	COG4964	Belongs to the GSP D family
YPD8_RS03600	COG4592	Periplasmic binding protein
YPD8_RS03620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPD8_RS03625	COG1684	flagellar biosynthetic protein fliR
YPD8_RS03655	COG1677	Flagellar hook-basal body complex protein FliE
YPD8_RS03695	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPD8_RS03700	COG1815	bacterial-type flagellum-dependent cell motility
YPD8_RS03710	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPD8_RS03740	COG4786	Flagellar basal body rod
YPD8_RS03750	COG1706	bacterial-type flagellum-dependent cell motility
YPD8_RS03760	COG1256	bacterial-type flagellum assembly
YPD8_RS03780	COG3710	Transcriptional regulator
YPD8_RS03800	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPD8_RS03825	COG1191	sigma factor activity
YPD8_RS03830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPD8_RS03880	COG2801	Transposase and inactivated derivatives
YPD8_RS03895	COG0471	metal ion transport
YPD8_RS03910	COG3209	COG3209 Rhs family protein
YPD8_RS03940	COG2610	gluconate transmembrane transporter activity
YPD8_RS03955	COG1132	(ABC) transporter
YPD8_RS03960	COG1132	(ABC) transporter
YPD8_RS03960	COG2375	cellular response to nickel ion
YPD8_RS03985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPD8_RS03985	COG3433	isochorismatase activity
YPD8_RS03985	COG2226	methyltransferase
YPD8_RS03995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPD8_RS03995	COG2226	methyltransferase
YPD8_RS03995	COG3433	isochorismatase activity
YPD8_RS04015	COG4771	TonB-dependent receptor
YPD8_RS04020	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPD8_RS04025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPD8_RS04065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPD8_RS04075	COG5001	Diguanylate cyclase
YPD8_RS04080	COG2801	Transposase and inactivated derivatives
YPD8_RS04090	COG2211	Major facilitator Superfamily
YPD8_RS04140	COG2771	luxR family
YPD8_RS04145	COG3916	Acyl-homoserine-lactone synthase
YPD8_RS04255	COG1982	Orn Lys Arg decarboxylase major
YPD8_RS04260	COG1879	ABC-type sugar transport system periplasmic component
YPD8_RS04265	COG1129	ABC transporter
YPD8_RS04270	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS04275	COG4774	siderophore transport
YPD8_RS04295	COG1194	a g-specific adenine glycosylase
YPD8_RS04305	COG3171	Protein conserved in bacteria
YPD8_RS04325	COG3064	Membrane
YPD8_RS04325	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPD8_RS04325	COG1073	alpha beta
YPD8_RS04330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPD8_RS04335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPD8_RS04345	COG0762	integral membrane protein
YPD8_RS04350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPD8_RS04355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPD8_RS04360	COG2805	Type II/IV secretion system protein
YPD8_RS04370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPD8_RS04385	COG0189	ligase activity
YPD8_RS04390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPD8_RS04395	COG2356	endonuclease I
YPD8_RS04410	COG1166	arginine decarboxylase activity
YPD8_RS04420	COG0501	Belongs to the peptidase M48B family
YPD8_RS04425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPD8_RS04445	COG0191	fructose-bisphosphate aldolase activity
YPD8_RS04480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPD8_RS04485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPD8_RS04500	COG0006	proline dipeptidase activity
YPD8_RS04505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPD8_RS04510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPD8_RS04540	COG5295	Hep Hag repeat protein
YPD8_RS04550	COG1272	protein, Hemolysin III
YPD8_RS04575	COG0745	RESPONSE REGULATOR receiver
YPD8_RS04580	COG2205	protein histidine kinase activity
YPD8_RS04585	COG4452	Inner membrane protein CreD
YPD8_RS04590	COG0716	FMN binding
YPD8_RS04595	COG4974	Belongs to the 'phage' integrase family
YPD8_RS04600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPD8_RS04605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPD8_RS04625	COG0582	viral genome integration into host DNA
YPD8_RS04655	COG2944	sequence-specific DNA binding
YPD8_RS04750	COG1695	Transcriptional regulator
YPD8_RS04755	COG0791	NLP P60 protein
YPD8_RS04765	COG1879	ABC-type sugar transport system periplasmic component
YPD8_RS04770	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS04775	COG1129	ABC transporter
YPD8_RS04790	COG1175	transmembrane transport
YPD8_RS04795	COG3833	ABC-type maltose transport systems, permease component
YPD8_RS04800	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPD8_RS04805	COG1874	Beta-galactosidase
YPD8_RS04810	COG1263	PTS System
YPD8_RS04810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPD8_RS04830	COG2271	Major facilitator Superfamily
YPD8_RS04860	COG3119	arylsulfatase activity
YPD8_RS04865	COG0641	radical SAM
YPD8_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS04885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS04890	COG3716	PTS system mannose fructose sorbose family IID component
YPD8_RS04895	COG3715	PTS system
YPD8_RS04900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPD8_RS04915	COG1349	DNA-binding transcription factor activity
YPD8_RS04920	COG3119	arylsulfatase activity
YPD8_RS04980	COG0288	reversible hydration of carbon dioxide
YPD8_RS05000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPD8_RS05070	COG0840	transmembrane signaling receptor activity
YPD8_RS05085	COG0583	DNA-binding transcription factor activity
YPD8_RS05090	COG2814	Major facilitator Superfamily
YPD8_RS05105	COG1609	Transcriptional regulator
YPD8_RS05135	COG0667	Aldo Keto reductase
YPD8_RS05195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPD8_RS05210	COG3130	regulation of translation
YPD8_RS05220	COG3009	Protein conserved in bacteria
YPD8_RS05225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPD8_RS05225	COG3008	intermembrane lipid transfer
YPD8_RS05230	COG2995	paraquat-inducible protein a
YPD8_RS05235	COG0488	(ABC) transporter
YPD8_RS05245	COG0633	Ferredoxin
YPD8_RS05245	COG3217	Mosc domain protein beta barrel domain protein
YPD8_RS05260	COG0308	aminopeptidase N
YPD8_RS05280	COG1448	Aminotransferase
YPD8_RS05285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPD8_RS05290	COG3108	Peptidase M15
YPD8_RS05295	COG2989	Protein conserved in bacteria
YPD8_RS05325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPD8_RS05335	COG3173	Aminoglycoside phosphotransferase
YPD8_RS05355	COG1278	Cold shock
YPD8_RS05365	COG5383	Protein conserved in bacteria
YPD8_RS05380	COG0658	competence protein
YPD8_RS05380	COG2333	competence protein COMEC
YPD8_RS05395	COG0539	negative regulation of cytoplasmic translation
YPD8_RS05420	COG5295	Hep Hag repeat protein
YPD8_RS05420	COG5295	Hep Hag repeat protein
YPD8_RS05425	COG0252	asparaginase activity
YPD8_RS05430	COG1944	ATP diphosphatase activity
YPD8_RS05435	COG2116	formate transmembrane transporter activity
YPD8_RS05440	COG1882	Formate acetyltransferase
YPD8_RS05450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPD8_RS05465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPD8_RS05485	COG0492	ferredoxin-NADP+ reductase activity
YPD8_RS05500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPD8_RS05510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPD8_RS05520	COG0542	response to heat
YPD8_RS05530	COG1278	Cold shock
YPD8_RS05540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPD8_RS05545	COG2990	Protein conserved in bacteria
YPD8_RS05550	COG3593	DNA synthesis involved in DNA repair
YPD8_RS05555	COG2431	L-lysine efflux transmembrane transporter activity
YPD8_RS05565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPD8_RS05570	COG0028	Belongs to the TPP enzyme family
YPD8_RS05575	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPD8_RS05580	COG0702	epimerase
YPD8_RS05585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPD8_RS05595	COG1605	Chorismate mutase
YPD8_RS05600	COG1126	abc transporter atp-binding protein
YPD8_RS05605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS05610	COG4215	(ABC) transporter
YPD8_RS05615	COG4160	amino acid transport
YPD8_RS05635	COG1120	ATPase activity
YPD8_RS05665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS05680	COG1177	transmembrane transport
YPD8_RS05685	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPD8_RS05690	COG3842	ATPase activity
YPD8_RS05695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPD8_RS05730	COG0671	phosphoesterase, PA-phosphatase related
YPD8_RS05740	COG1349	DNA-binding transcription factor activity
YPD8_RS05745	COG0814	amino acid
YPD8_RS05755	COG1686	Belongs to the peptidase S11 family
YPD8_RS05760	COG2011	ABC-type metal ion transport system permease component
YPD8_RS05785	COG0625	glutathione transferase activity
YPD8_RS05790	COG4771	TonB-dependent receptor
YPD8_RS05800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPD8_RS05810	COG0833	amino acid
YPD8_RS05815	COG0583	DNA-binding transcription factor activity
YPD8_RS05820	COG2855	membrane
YPD8_RS05835	COG3121	Chaperone
YPD8_RS05850	COG3710	Transcriptional regulator
YPD8_RS05860	COG1105	Belongs to the carbohydrate kinase PfkB family
YPD8_RS05870	COG0494	nUDIX hydrolase
YPD8_RS05880	COG1129	ABC transporter
YPD8_RS05915	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS05945	COG2186	Transcriptional regulator
YPD8_RS05960	COG0671	phosphoesterase, PA-phosphatase related
YPD8_RS05965	COG0791	NLP P60 protein
YPD8_RS05970	COG2200	EAL domain
YPD8_RS05980	COG4174	ABC transporter (Permease)
YPD8_RS05985	COG4239	(ABC) transporter, permease
YPD8_RS05990	COG4172	Belongs to the ABC transporter superfamily
YPD8_RS06000	COG2814	Major facilitator Superfamily
YPD8_RS06005	COG1187	pseudouridine synthase activity
YPD8_RS06010	COG1061	Type III restriction enzyme res subunit
YPD8_RS06035	COG3082	Protein of unknown function (DUF1414)
YPD8_RS06040	COG3083	sulfuric ester hydrolase activity
YPD8_RS06055	COG3157	Type VI secretion system effector, Hcp
YPD8_RS06075	COG2723	6-phospho-beta-galactosidase activity
YPD8_RS06080	COG1737	Transcriptional regulator
YPD8_RS06100	COG3299	homolog of phage Mu protein gp47
YPD8_RS06140	COG4386	tail sheath protein
YPD8_RS06160	COG3622	Belongs to the hyi family
YPD8_RS06165	COG1349	DNA-binding transcription factor activity
YPD8_RS06175	COG3395	kinase activity
YPD8_RS06220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPD8_RS06250	COG2223	nitrite transmembrane transporter activity
YPD8_RS06255	COG2198	Histidine kinase
YPD8_RS06255	COG0642	Histidine kinase
YPD8_RS06270	COG0784	Response regulator, receiver
YPD8_RS06270	COG2205	protein histidine kinase activity
YPD8_RS06300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPD8_RS06315	COG0814	amino acid
YPD8_RS06340	COG0697	spore germination
YPD8_RS06350	COG1982	Orn Lys Arg decarboxylase major
YPD8_RS06355	COG0531	amino acid
YPD8_RS06360	COG1174	glycine betaine transport
YPD8_RS06365	COG1125	glycine betaine transport
YPD8_RS06370	COG1174	glycine betaine transport
YPD8_RS06375	COG1732	Glycine betaine
YPD8_RS06380	COG1732	Glycine betaine
YPD8_RS06385	COG2897	thiosulfate sulfurtransferase activity
YPD8_RS06405	COG1122	ATPase activity
YPD8_RS06425	COG4807	Protein conserved in bacteria
YPD8_RS06440	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPD8_RS06450	COG2261	transglycosylase associated protein
YPD8_RS06470	COG0277	FAD linked oxidase domain protein
YPD8_RS06475	COG1686	Belongs to the peptidase S11 family
YPD8_RS06485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPD8_RS06500	COG2211	Major facilitator Superfamily
YPD8_RS06505	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPD8_RS06515	COG0583	DNA-binding transcription factor activity
YPD8_RS06520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPD8_RS06550	COG0670	Belongs to the BI1 family
YPD8_RS06555	COG0314	molybdopterin synthase activity
YPD8_RS06560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPD8_RS06570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPD8_RS06580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPD8_RS06585	COG4628	conserved protein (DUF2132)
YPD8_RS06595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YPD8_RS06605	COG2226	methyltransferase
YPD8_RS06630	COG0561	phosphatase activity
YPD8_RS06640	COG4149	molybdate abc transporter
YPD8_RS06645	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPD8_RS06655	COG3585	molybdate ion transport
YPD8_RS06655	COG2005	Transcriptional regulator
YPD8_RS06660	COG1119	ATPase activity
YPD8_RS06680	COG1085	galactose-1-phosphate uridylyltransferase
YPD8_RS06695	COG2017	converts alpha-aldose to the beta-anomer
YPD8_RS06710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPD8_RS06725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPD8_RS06730	COG1230	cation diffusion facilitator family transporter
YPD8_RS06760	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPD8_RS06765	COG2885	chlorophyll binding
YPD8_RS06780	COG0848	biopolymer transport protein
YPD8_RS06785	COG0811	peptide transport
YPD8_RS06790	COG0824	Thioesterase
YPD8_RS06795	COG3790	cyd operon protein YbgE
YPD8_RS06800	COG4890	Cyd operon protein YbgT
YPD8_RS06805	COG1294	oxidase, subunit
YPD8_RS06810	COG1271	oxidase subunit
YPD8_RS06815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPD8_RS06825	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPD8_RS06830	COG0567	Dehydrogenase, E1 component
YPD8_RS06845	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPD8_RS06850	COG2009	succinate dehydrogenase
YPD8_RS06870	COG0497	DNA recombination
YPD8_RS06875	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPD8_RS06885	COG2867	negative regulation of translational initiation
YPD8_RS06905	COG0582	viral genome integration into host DNA
YPD8_RS06965	COG3657	addiction module killer protein
YPD8_RS07000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPD8_RS07010	COG1074	ATP-dependent DNA helicase activity
YPD8_RS07015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPD8_RS07025	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPD8_RS07040	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPD8_RS07045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPD8_RS07050	COG2166	iron-sulfur cluster assembly
YPD8_RS07065	COG2363	Small membrane protein
YPD8_RS07080	COG1611	Belongs to the LOG family
YPD8_RS07100	COG3098	single-species biofilm formation
YPD8_RS07105	COG0564	pseudouridine synthase activity
YPD8_RS07165	COG0575	Belongs to the CDS family
YPD8_RS07170	COG0750	zinc metalloprotease
YPD8_RS07185	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPD8_RS07210	COG0587	DNA-directed DNA polymerase activity
YPD8_RS07220	COG0346	lactoylglutathione lyase activity
YPD8_RS07235	COG4568	rho-dependent transcription termination
YPD8_RS07245	COG4681	YaeQ
YPD8_RS07255	COG3015	lipoprotein NlpE involved in copper resistance
YPD8_RS07265	COG1720	tRNA m6t6A37 methyltransferase activity
YPD8_RS07275	COG1464	Belongs to the NlpA lipoprotein family
YPD8_RS07280	COG2011	ABC-type metal ion transport system permease component
YPD8_RS07290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPD8_RS07325	COG0656	L-ascorbic acid biosynthetic process
YPD8_RS07345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPD8_RS07350	COG2226	methyltransferase
YPD8_RS07395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPD8_RS07410	COG1067	ATP-dependent peptidase activity
YPD8_RS07440	COG3070	regulator of competence-specific genes
YPD8_RS07445	COG1289	transmembrane transporter activity
YPD8_RS07450	COG3304	Inner membrane component domain
YPD8_RS07455	COG0210	DNA helicase
YPD8_RS07470	COG1832	CoA-binding protein
YPD8_RS07490	COG2920	part of a sulfur-relay system
YPD8_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS07535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPD8_RS07540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPD8_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS07550	COG3425	synthase
YPD8_RS07560	COG1024	Enoyl-CoA hydratase
YPD8_RS07565	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS07575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPD8_RS07580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPD8_RS07740	COG0488	(ABC) transporter
YPD8_RS07750	COG3328	transposase activity
YPD8_RS07785	COG3047	cAMP biosynthetic process
YPD8_RS07805	COG0135	phosphoribosylanthranilate isomerase activity
YPD8_RS07805	COG0134	indole-3-glycerol-phosphate synthase activity
YPD8_RS07815	COG0512	Glutamine amidotransferase of anthranilate synthase
YPD8_RS07840	COG0009	L-threonylcarbamoyladenylate synthase
YPD8_RS07855	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS07880	COG0583	DNA-binding transcription factor activity
YPD8_RS07900	COG0671	phosphoesterase, PA-phosphatase related
YPD8_RS07905	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPD8_RS07910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPD8_RS07925	COG0023	Translation Initiation Factor
YPD8_RS07945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPD8_RS07950	COG2879	small protein
YPD8_RS07955	COG1966	Carbon starvation protein
YPD8_RS07965	COG2271	Major facilitator Superfamily
YPD8_RS07970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPD8_RS07975	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPD8_RS07985	COG4659	FMN binding
YPD8_RS07990	COG4658	electron transport chain
YPD8_RS07995	COG2207	Transcriptional regulator
YPD8_RS07995	COG3708	Transcriptional regulator
YPD8_RS08025	COG1132	(ABC) transporter
YPD8_RS08035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPD8_RS08040	COG2274	protein secretion by the type I secretion system
YPD8_RS08055	COG1879	ABC-type sugar transport system periplasmic component
YPD8_RS08060	COG1129	ABC transporter
YPD8_RS08065	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS08075	COG0673	inositol 2-dehydrogenase activity
YPD8_RS08080	COG0385	Bile acid
YPD8_RS08090	COG5339	Protein conserved in bacteria
YPD8_RS08115	COG0583	DNA-binding transcription factor activity
YPD8_RS08120	COG1940	carbohydrate kinase activity
YPD8_RS08125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPD8_RS08130	COG0038	chloride channel
YPD8_RS08140	COG1609	Transcriptional regulator
YPD8_RS08160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPD8_RS08165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPD8_RS08190	COG0028	Belongs to the TPP enzyme family
YPD8_RS08195	COG0440	acetolactate synthase activity
YPD8_RS08200	COG1011	Hydrolase
YPD8_RS08220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPD8_RS08225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPD8_RS08230	COG0589	response to stress
YPD8_RS08235	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPD8_RS08240	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPD8_RS08255	COG0531	amino acid
YPD8_RS08265	COG0745	RESPONSE REGULATOR receiver
YPD8_RS08270	COG2205	protein histidine kinase activity
YPD8_RS08275	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPD8_RS08310	COG3038	cytochrome b561
YPD8_RS08325	COG3591	Belongs to the peptidase S1B family
YPD8_RS08340	COG1643	Atp-dependent helicase
YPD8_RS08350	COG2390	Transcriptional regulator
YPD8_RS08355	COG0246	Mannitol dehydrogenase
YPD8_RS08370	COG2911	Protein conserved in bacteria
YPD8_RS08375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPD8_RS08380	COG3187	Heat shock protein
YPD8_RS08385	COG3042	response to heat
YPD8_RS08390	COG1285	pathogenesis
YPD8_RS08400	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPD8_RS08400	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPD8_RS08400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPD8_RS08400	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPD8_RS08410	COG0657	acetylesterase activity
YPD8_RS08430	COG4166	transmembrane transport
YPD8_RS08435	COG2866	Carboxypeptidase
YPD8_RS08440	COG4948	Mandelate Racemase Muconate Lactonizing
YPD8_RS08445	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPD8_RS08480	COG5642	Protein of unknown function (DUF2384)
YPD8_RS08485	COG5654	RES domain protein
YPD8_RS08495	COG3106	COG3106 Predicted ATPase
YPD8_RS08505	COG1983	PspC domain protein
YPD8_RS08515	COG1842	Phage shock protein A
YPD8_RS08520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPD8_RS08540	COG4166	transmembrane transport
YPD8_RS08545	COG4168	peptide transport system, permease
YPD8_RS08550	COG4171	peptide transport system, permease
YPD8_RS08560	COG4172	Belongs to the ABC transporter superfamily
YPD8_RS08565	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPD8_RS08565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPD8_RS08570	COG3104	oligopeptide transport
YPD8_RS08585	COG0625	glutathione transferase activity
YPD8_RS08605	COG3895	Periplasmic Protein
YPD8_RS08615	COG3133	Outer membrane lipoprotein
YPD8_RS08625	COG4989	oxidoreductase activity
YPD8_RS08630	COG3313	Fe-S protein
YPD8_RS08635	COG2194	sulfuric ester hydrolase activity
YPD8_RS08640	COG1309	transcriptional regulator
YPD8_RS08645	COG1902	pentaerythritol trinitrate reductase activity
YPD8_RS08655	COG0346	lactoylglutathione lyase activity
YPD8_RS08660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPD8_RS08665	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPD8_RS08675	COG0791	NLP P60 protein
YPD8_RS08690	COG0583	DNA-binding transcription factor activity
YPD8_RS08695	COG2814	Major facilitator Superfamily
YPD8_RS08700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPD8_RS08705	COG0307	riboflavin synthase, alpha
YPD8_RS08755	COG1376	ErfK ybiS ycfS ynhG family protein
YPD8_RS08755	COG1388	LysM domain
YPD8_RS08770	COG0719	Fe-S assembly protein
YPD8_RS08775	COG0396	ATPase activity
YPD8_RS08780	COG0719	Fe-S assembly protein
YPD8_RS08785	COG0316	Belongs to the HesB IscA family
YPD8_RS08795	COG2050	protein possibly involved in aromatic compounds catabolism
YPD8_RS08800	COG0247	lactate metabolic process
YPD8_RS08800	COG0277	FAD linked oxidase domain protein
YPD8_RS08805	COG0628	permease
YPD8_RS08810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPD8_RS08810	COG0574	Belongs to the PEP-utilizing enzyme family
YPD8_RS08835	COG0791	NLP P60 protein
YPD8_RS08880	COG0386	Belongs to the glutathione peroxidase family
YPD8_RS08905	COG0776	regulation of translation
YPD8_RS08910	COG0072	phenylalanine-tRNA ligase activity
YPD8_RS08910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPD8_RS08940	COG4249	Peptidase C14 caspase catalytic subunit p20
YPD8_RS08965	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPD8_RS08970	COG1121	(ABC) transporter
YPD8_RS08975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPD8_RS08980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPD8_RS08990	COG3001	Fructosamine kinase
YPD8_RS09000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPD8_RS09005	COG3328	transposase activity
YPD8_RS09010	COG2223	nitrite transmembrane transporter activity
YPD8_RS09030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPD8_RS09055	COG3122	Protein conserved in bacteria
YPD8_RS09075	COG0534	Mate efflux family protein
YPD8_RS09090	COG4948	Mandelate Racemase Muconate Lactonizing
YPD8_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS09105	COG3011	Protein conserved in bacteria
YPD8_RS09110	COG2271	Major facilitator Superfamily
YPD8_RS09115	COG1470	cell adhesion involved in biofilm formation
YPD8_RS09115	COG1388	LysM domain
YPD8_RS09120	COG3328	transposase activity
YPD8_RS09135	COG2925	Exonuclease
YPD8_RS09140	COG0531	amino acid
YPD8_RS09150	COG0371	Dehydrogenase
YPD8_RS09155	COG1129	ABC transporter
YPD8_RS09160	COG1129	ABC transporter
YPD8_RS09165	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS09175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPD8_RS09185	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPD8_RS09195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPD8_RS09195	COG0131	Imidazoleglycerol-phosphate dehydratase
YPD8_RS09215	COG0140	phosphoribosyl-ATP diphosphatase activity
YPD8_RS09215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPD8_RS09225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPD8_RS09230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPD8_RS09245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPD8_RS09250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPD8_RS09255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPD8_RS09260	COG1120	ATPase activity
YPD8_RS09275	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPD8_RS09280	COG0076	glutamate decarboxylase activity
YPD8_RS09285	COG4114	ferric iron reductase
YPD8_RS09290	COG1253	flavin adenine dinucleotide binding
YPD8_RS09295	COG2982	Protein involved in outer membrane biogenesis
YPD8_RS09310	COG0489	protein tyrosine kinase activity
YPD8_RS09345	COG2814	Major facilitator Superfamily
YPD8_RS09355	COG1346	cytolysis
YPD8_RS09370	COG2949	membrane
YPD8_RS09375	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS09390	COG2311	Membrane
YPD8_RS09400	COG0477	Major facilitator Superfamily
YPD8_RS09405	COG0583	DNA-binding transcription factor activity
YPD8_RS09440	COG1136	(ABC) transporter
YPD8_RS09450	COG0303	'Molybdopterin
YPD8_RS09460	COG3328	transposase activity
YPD8_RS09465	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPD8_RS09470	COG2350	Protein conserved in bacteria
YPD8_RS09510	COG4608	Belongs to the ABC transporter superfamily
YPD8_RS09515	COG0444	Belongs to the ABC transporter superfamily
YPD8_RS09520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPD8_RS09525	COG0601	transmembrane transport
YPD8_RS09535	COG2095	MarC family integral membrane protein
YPD8_RS09540	COG1454	alcohol dehydrogenase
YPD8_RS09540	COG1012	belongs to the aldehyde dehydrogenase family
YPD8_RS09570	COG0745	RESPONSE REGULATOR receiver
YPD8_RS09580	COG0788	formyltetrahydrofolate deformylase activity
YPD8_RS09585	COG3328	transposase activity
YPD8_RS09595	COG0583	DNA-binding transcription factor activity
YPD8_RS09600	COG0708	Exodeoxyribonuclease III
YPD8_RS09605	COG0494	nUDIX hydrolase
YPD8_RS09615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPD8_RS09620	COG0709	Synthesizes selenophosphate from selenide and ATP
YPD8_RS09625	COG0778	Nitroreductase
YPD8_RS09630	COG0616	signal peptide processing
YPD8_RS09635	COG0252	asparaginase activity
YPD8_RS09640	COG1335	isochorismatase
YPD8_RS09645	COG3139	Protein of unknown function (DUF1315)
YPD8_RS09665	COG3713	MltA-interacting MipA family protein
YPD8_RS09670	COG2766	serine protein kinase
YPD8_RS09685	COG0583	DNA-binding transcription factor activity
YPD8_RS09695	COG2814	Major facilitator Superfamily
YPD8_RS09705	COG2719	SpoVR family
YPD8_RS09735	COG1104	cysteine desulfurase activity
YPD8_RS09745	COG3328	transposase activity
YPD8_RS10020	COG0582	viral genome integration into host DNA
YPD8_RS10030	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPD8_RS10035	COG2951	lytic endotransglycosylase activity
YPD8_RS10050	COG2894	cell division
YPD8_RS10055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPD8_RS10060	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPD8_RS10065	COG0318	PFAM AMP-dependent synthetase and ligase
YPD8_RS10070	COG3065	identical protein binding
YPD8_RS10080	COG1199	ATP-dependent helicase activity
YPD8_RS10085	COG0251	oxidation-reduction process
YPD8_RS10100	COG0800	Aldolase
YPD8_RS10105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPD8_RS10110	COG1737	Transcriptional regulator
YPD8_RS10115	COG0469	pyruvate kinase activity
YPD8_RS10120	COG1560	Kdo2-lipid A biosynthetic process
YPD8_RS10125	COG0739	heme binding
YPD8_RS10130	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPD8_RS10140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPD8_RS10165	COG0494	nUDIX hydrolase
YPD8_RS10175	COG1801	Protein of unknown function DUF72
YPD8_RS10180	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPD8_RS10200	COG3102	Protein conserved in bacteria
YPD8_RS10220	COG0728	peptidoglycan biosynthetic process
YPD8_RS10225	COG0673	inositol 2-dehydrogenase activity
YPD8_RS10230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPD8_RS10245	COG3381	protein complex oligomerization
YPD8_RS10260	COG1940	carbohydrate kinase activity
YPD8_RS10265	COG0584	glycerophosphoryl diester phosphodiesterase
YPD8_RS10270	COG3842	ATPase activity
YPD8_RS10285	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPD8_RS10290	COG3833	ABC-type maltose transport systems, permease component
YPD8_RS10315	COG0659	secondary active sulfate transmembrane transporter activity
YPD8_RS10335	COG2890	protein-(glutamine-N5) methyltransferase activity
YPD8_RS10365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPD8_RS10385	COG0012	GTP binding
YPD8_RS10440	COG5002	protein histidine kinase activity
YPD8_RS10480	COG0500	methyltransferase
YPD8_RS10505	COG3328	transposase activity
YPD8_RS10550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPD8_RS10555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPD8_RS10560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPD8_RS10575	COG0402	S-adenosylhomocysteine deaminase activity
YPD8_RS10640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPD8_RS10645	COG3850	Histidine kinase
YPD8_RS10670	COG3658	cytochrome
YPD8_RS10675	COG1215	transferase activity, transferring glycosyl groups
YPD8_RS10680	COG0726	polysaccharide deacetylase
YPD8_RS10680	COG1649	PFAM Uncharacterised BCR, COG1649
YPD8_RS10685	COG0457	Tetratricopeptide repeat
YPD8_RS10690	COG0006	proline dipeptidase activity
YPD8_RS10710	COG1136	(ABC) transporter
YPD8_RS10710	COG0577	efflux transmembrane transporter activity
YPD8_RS10720	COG1136	(ABC) transporter
YPD8_RS10720	COG0577	efflux transmembrane transporter activity
YPD8_RS10735	COG0672	)-iron permease
YPD8_RS10745	COG2066	Belongs to the glutaminase family
YPD8_RS10755	COG1349	DNA-binding transcription factor activity
YPD8_RS10765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPD8_RS10770	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPD8_RS10785	COG2814	Major facilitator Superfamily
YPD8_RS10810	COG2030	dehydratase
YPD8_RS10815	COG0427	acetyl-CoA hydrolase
YPD8_RS10825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS10825	COG2205	protein histidine kinase activity
YPD8_RS10840	COG3188	usher protein
YPD8_RS10850	COG3121	Chaperone
YPD8_RS10860	COG0582	viral genome integration into host DNA
YPD8_RS10865	COG1169	isochorismate synthase
YPD8_RS10870	COG2814	Major facilitator Superfamily
YPD8_RS10890	COG2226	methyltransferase
YPD8_RS10890	COG3433	isochorismatase activity
YPD8_RS10890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPD8_RS10910	COG1021	2,3-dihydroxybenzoate-AMP ligase
YPD8_RS10915	COG4771	TonB-dependent receptor
YPD8_RS10990	COG3842	ATPase activity
YPD8_RS10995	COG0395	ABC-type sugar transport system, permease component
YPD8_RS11000	COG1175	transmembrane transport
YPD8_RS11010	COG0673	inositol 2-dehydrogenase activity
YPD8_RS11020	COG2188	Transcriptional regulator
YPD8_RS11170	COG2197	response regulator
YPD8_RS11180	COG3136	membrane protein required for alginate biosynthesis
YPD8_RS11205	COG1113	amino acid transport
YPD8_RS11225	COG2822	iron ion transport
YPD8_RS11230	COG0672	)-iron permease
YPD8_RS11260	COG1126	abc transporter atp-binding protein
YPD8_RS11265	COG0765	amino acid transport
YPD8_RS11270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS11285	COG1191	sigma factor activity
YPD8_RS11320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YPD8_RS11325	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPD8_RS11330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPD8_RS11345	COG1677	Flagellar hook-basal body complex protein FliE
YPD8_RS11365	COG1157	protein secretion by the type III secretion system
YPD8_RS11380	COG1580	Controls the rotational direction of flagella during chemotaxis
YPD8_RS11405	COG1987	bacterial-type flagellum assembly
YPD8_RS11425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPD8_RS11430	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS11435	COG1129	ABC transporter
YPD8_RS11445	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS11455	COG2390	Transcriptional regulator
YPD8_RS11465	COG1256	bacterial-type flagellum assembly
YPD8_RS11505	COG1558	bacterial-type flagellum-dependent cell motility
YPD8_RS11510	COG1815	bacterial-type flagellum-dependent cell motility
YPD8_RS11520	COG2747	anti-sigma28 factor FlgM
YPD8_RS11525	COG3418	PFAM FlgN family protein
YPD8_RS11550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPD8_RS11555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPD8_RS11585	COG2372	response to copper ion
YPD8_RS11590	COG1528	Iron-storage protein
YPD8_RS11605	COG1770	oligopeptidase
YPD8_RS11620	COG3141	response to X-ray
YPD8_RS11625	COG0513	Belongs to the DEAD box helicase family
YPD8_RS11650	COG1760	l-serine dehydratase
YPD8_RS11655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPD8_RS11660	COG2368	4-hydroxyphenylacetate
YPD8_RS11675	COG3971	2-oxopent-4-enoate hydratase activity
YPD8_RS11685	COG3384	dioxygenase
YPD8_RS11690	COG1012	belongs to the aldehyde dehydrogenase family
YPD8_RS11705	COG1846	Transcriptional regulator
YPD8_RS11710	COG1253	flavin adenine dinucleotide binding
YPD8_RS11715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPD8_RS11715	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS11720	COG3715	PTS system
YPD8_RS11725	COG3716	PTS system mannose fructose sorbose family IID component
YPD8_RS11745	COG5001	Diguanylate cyclase
YPD8_RS11745	COG5002	protein histidine kinase activity
YPD8_RS11745	COG3447	MASE1 domain protein
YPD8_RS11755	COG2226	methyltransferase
YPD8_RS11760	COG1496	oxidoreductase activity
YPD8_RS11785	COG1113	amino acid transport
YPD8_RS11820	COG2207	Transcriptional regulator
YPD8_RS11830	COG1132	(ABC) transporter
YPD8_RS11875	COG3328	transposase activity
YPD8_RS11890	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS11900	COG1175	transmembrane transport
YPD8_RS11905	COG0395	ABC-type sugar transport system, permease component
YPD8_RS11910	COG3842	ATPase activity
YPD8_RS11915	COG1653	transport
YPD8_RS11920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPD8_RS11925	COG1988	membrane-bound metal-dependent
YPD8_RS11930	COG1823	symporter activity
YPD8_RS11935	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPD8_RS11945	COG0823	Involved in the tonB-independent uptake of proteins
YPD8_RS11950	COG2814	Major facilitator Superfamily
YPD8_RS11955	COG3121	Chaperone
YPD8_RS11970	COG3121	Chaperone
YPD8_RS11975	COG3539	Fimbrial protein
YPD8_RS11985	COG0793	Belongs to the peptidase S41A family
YPD8_RS11995	COG1956	GAF domain-containing protein
YPD8_RS12005	COG3008	intermembrane lipid transfer
YPD8_RS12025	COG3121	Chaperone
YPD8_RS12080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPD8_RS12090	COG5295	Hep Hag repeat protein
YPD8_RS12100	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPD8_RS12110	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPD8_RS12115	COG0745	RESPONSE REGULATOR receiver
YPD8_RS12125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPD8_RS12130	COG0840	transmembrane signaling receptor activity
YPD8_RS12135	COG0840	transmembrane signaling receptor activity
YPD8_RS12155	COG2964	Protein conserved in bacteria
YPD8_RS12165	COG0251	oxidation-reduction process
YPD8_RS12170	COG2271	Major facilitator Superfamily
YPD8_RS12175	COG0835	chemotaxis
YPD8_RS12180	COG0643	Histidine kinase
YPD8_RS12180	COG2198	Histidine kinase
YPD8_RS12185	COG1360	Flagellar Motor Protein
YPD8_RS12210	COG1285	pathogenesis
YPD8_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS12240	COG0604	alcohol dehydrogenase
YPD8_RS12240	COG3321	synthase
YPD8_RS12250	COG1522	sequence-specific DNA binding
YPD8_RS12275	COG1733	regulation of RNA biosynthetic process
YPD8_RS12280	COG0702	epimerase
YPD8_RS12285	COG0840	transmembrane signaling receptor activity
YPD8_RS12305	COG1187	pseudouridine synthase activity
YPD8_RS12335	COG0745	RESPONSE REGULATOR receiver
YPD8_RS12345	COG2850	peptidyl-arginine hydroxylation
YPD8_RS12365	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPD8_RS12375	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPD8_RS12385	COG3134	Outer membrane lipoprotein
YPD8_RS12390	COG3328	transposase activity
YPD8_RS12405	COG1252	NADH dehydrogenase
YPD8_RS12415	COG1472	Belongs to the glycosyl hydrolase 3 family
YPD8_RS12430	COG5633	Lipoprotein
YPD8_RS12435	COG0537	adenosine 5'-monophosphoramidase activity
YPD8_RS12440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPD8_RS12450	COG1263	PTS System
YPD8_RS12450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPD8_RS12455	COG0084	hydrolase, TatD family'
YPD8_RS12460	COG0470	DNA polymerase III
YPD8_RS12470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPD8_RS12475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPD8_RS12520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPD8_RS12525	COG1399	metal-binding, possibly nucleic acid-binding protein
YPD8_RS12530	COG0424	maF-like protein
YPD8_RS12545	COG0564	pseudouridine synthase activity
YPD8_RS12550	COG1530	ribonuclease E activity
YPD8_RS12555	COG3328	transposase activity
YPD8_RS12570	COG1609	Transcriptional regulator
YPD8_RS12575	COG0280	phosphate acetyltransferase
YPD8_RS12575	COG0857	belongs to the CobB CobQ family
YPD8_RS12600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPD8_RS12605	COG0490	domain, Protein
YPD8_RS12605	COG0471	metal ion transport
YPD8_RS12620	COG0436	Aminotransferase
YPD8_RS12630	COG0583	DNA-binding transcription factor activity
YPD8_RS12660	COG1034	ATP synthesis coupled electron transport
YPD8_RS12675	COG0839	Belongs to the complex I subunit 6 family
YPD8_RS12685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPD8_RS12690	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPD8_RS12705	COG2731	YhcH YjgK YiaL family protein
YPD8_RS12710	COG3265	gluconokinase activity
YPD8_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS12720	COG1649	PFAM Uncharacterised BCR, COG1649
YPD8_RS12725	COG1609	Transcriptional regulator
YPD8_RS12735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPD8_RS12765	COG4575	ribosome binding
YPD8_RS12775	COG1169	isochorismate synthase
YPD8_RS12790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPD8_RS12805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPD8_RS12840	COG1126	abc transporter atp-binding protein
YPD8_RS12845	COG0765	amino acid transport
YPD8_RS12850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS12880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPD8_RS12900	COG1063	alcohol dehydrogenase
YPD8_RS12910	COG1129	ABC transporter
YPD8_RS12915	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS12920	COG1609	Transcriptional regulator
YPD8_RS12925	COG0583	DNA-binding transcription factor activity
YPD8_RS12930	COG0473	3-isopropylmalate dehydrogenase activity
YPD8_RS12940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPD8_RS12945	COG4638	Rieske (2fe-2S)
YPD8_RS12950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPD8_RS12955	COG2831	hemolysin activation secretion protein
YPD8_RS13000	COG3210	domain, Protein
YPD8_RS13010	COG3842	ATPase activity
YPD8_RS13020	COG1609	Transcriptional regulator
YPD8_RS13035	COG0395	ABC-type sugar transport system, permease component
YPD8_RS13040	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPD8_RS13060	COG0668	transmembrane transport
YPD8_RS13065	COG1518	maintenance of DNA repeat elements
YPD8_RS13095	COG0667	Aldo Keto reductase
YPD8_RS13105	COG0477	Major facilitator Superfamily
YPD8_RS13115	COG0583	DNA-binding transcription factor activity
YPD8_RS13120	COG2771	luxR family
YPD8_RS13125	COG3916	Acyl-homoserine-lactone synthase
YPD8_RS13155	COG0628	permease
YPD8_RS13170	COG3328	transposase activity
YPD8_RS13195	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPD8_RS13200	COG3328	transposase activity
YPD8_RS13205	COG4953	penicillin-binding protein 1C
YPD8_RS13210	COG2373	Large extracellular alpha-helical protein
YPD8_RS13230	COG3962	Belongs to the TPP enzyme family
YPD8_RS13245	COG1129	ABC transporter
YPD8_RS13255	COG0673	inositol 2-dehydrogenase activity
YPD8_RS13260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPD8_RS13270	COG3718	enzyme involved in inositol metabolism
YPD8_RS13280	COG5265	(ABC) transporter
YPD8_RS13310	COG1278	Cold shock
YPD8_RS13320	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPD8_RS13330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPD8_RS13355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPD8_RS13360	COG0772	Belongs to the SEDS family
YPD8_RS13365	COG0768	penicillin binding
YPD8_RS13375	COG0799	negative regulation of ribosome biogenesis
YPD8_RS13385	COG1466	dna polymerase III delta subunit
YPD8_RS13400	COG2888	peptidyl-tyrosine sulfation
YPD8_RS13405	COG1126	abc transporter atp-binding protein
YPD8_RS13415	COG0765	amino acid transport
YPD8_RS13425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPD8_RS13430	COG4535	Mg2 and Co2 transporter CorC
YPD8_RS13440	COG1702	phosphate starvation-inducible protein PhoH
YPD8_RS13445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YPD8_RS13450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPD8_RS13490	COG0367	asparagine synthase
YPD8_RS13500	COG1940	carbohydrate kinase activity
YPD8_RS13500	COG1846	Transcriptional regulator
YPD8_RS13505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPD8_RS13515	COG2190	(PTS) system
YPD8_RS13515	COG1263	PTS System
YPD8_RS13515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPD8_RS13540	COG0735	belongs to the Fur family
YPD8_RS13560	COG0596	Alpha beta hydrolase
YPD8_RS13570	COG0582	viral genome integration into host DNA
YPD8_RS13575	COG2963	transposase activity
YPD8_RS13580	COG0582	viral genome integration into host DNA
YPD8_RS13600	COG2113	Glycine betaine
YPD8_RS13605	COG4176	ABC-type proline glycine betaine transport system permease component
YPD8_RS13610	COG4175	Glycine betaine
YPD8_RS13615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPD8_RS13670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPD8_RS13675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPD8_RS13680	COG1124	(ABC) transporter
YPD8_RS13685	COG0831	urea catabolic process
YPD8_RS13710	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPD8_RS13720	COG4413	Urea transporter
YPD8_RS13725	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPD8_RS13740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPD8_RS13750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPD8_RS13760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPD8_RS13765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPD8_RS13770	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPD8_RS13775	COG2169	Transcriptional regulator
YPD8_RS13775	COG1917	Cupin 2, conserved barrel domain protein
YPD8_RS13795	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPD8_RS13800	COG0033	Phosphoglucomutase
YPD8_RS13820	COG0745	RESPONSE REGULATOR receiver
YPD8_RS13860	COG3272	Protein of unknown function (DUF1722)
YPD8_RS13870	COG5212	phosphodiesterase
YPD8_RS13875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPD8_RS13885	COG1984	allophanate hydrolase subunit 2
YPD8_RS13935	COG0513	Belongs to the DEAD box helicase family
YPD8_RS13945	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPD8_RS13960	COG3026	antisigma factor binding
YPD8_RS13965	COG3086	response to oxidative stress
YPD8_RS14010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPD8_RS14030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPD8_RS14035	COG1737	Transcriptional regulator
YPD8_RS14045	COG0560	Phosphoserine phosphatase
YPD8_RS14085	COG2205	protein histidine kinase activity
YPD8_RS14090	COG3170	Tfp pilus assembly protein FimV
YPD8_RS14095	COG2204	response regulator
YPD8_RS14100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPD8_RS14100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPD8_RS14105	COG0347	Belongs to the P(II) protein family
YPD8_RS14110	COG2188	Transcriptional regulator
YPD8_RS14115	COG2188	Transcriptional regulator
YPD8_RS14120	COG1017	nitric oxide dioxygenase activity
YPD8_RS14120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPD8_RS14145	COG3711	transcriptional antiterminator
YPD8_RS14150	COG3683	transport system, periplasmic component
YPD8_RS14155	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPD8_RS14185	COG0822	iron-sulfur transferase activity
YPD8_RS14200	COG0443	Heat shock 70 kDa protein
YPD8_RS14205	COG0633	Ferredoxin
YPD8_RS14210	COG2975	iron-sulfur cluster assembly
YPD8_RS14230	COG3468	outer membrane autotransporter barrel domain protein
YPD8_RS14235	COG3468	outer membrane autotransporter barrel domain protein
YPD8_RS14280	COG2976	Protein conserved in bacteria
YPD8_RS14285	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPD8_RS14300	COG1645	bacterial-type flagellum-dependent swarming motility
YPD8_RS14310	COG0516	GMP reductase activity
YPD8_RS14310	COG0517	IMP dehydrogenase activity
YPD8_RS14365	COG3328	transposase activity
YPD8_RS14380	COG0351	phosphomethylpyrimidine kinase
YPD8_RS14400	COG0826	peptidase U32
YPD8_RS14405	COG3422	double-strand break repair
YPD8_RS14410	COG0745	RESPONSE REGULATOR receiver
YPD8_RS14415	COG2205	protein histidine kinase activity
YPD8_RS14420	COG2205	protein histidine kinase activity
YPD8_RS14445	COG3842	ATPase activity
YPD8_RS14455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPD8_RS14465	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPD8_RS14470	COG1177	transmembrane transport
YPD8_RS14475	COG0443	Heat shock 70 kDa protein
YPD8_RS14480	COG2239	Acts as a magnesium transporter
YPD8_RS14495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPD8_RS14505	COG0581	inorganic phosphate transmembrane transporter activity
YPD8_RS14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPD8_RS14530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPD8_RS14550	COG2501	S4 domain
YPD8_RS14600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPD8_RS14605	COG4589	Belongs to the CDS family
YPD8_RS14615	COG2267	carboxylic ester hydrolase activity
YPD8_RS14620	COG2453	phosphatase
YPD8_RS14620	COG0671	phosphoesterase, PA-phosphatase related
YPD8_RS14650	COG0667	Aldo Keto reductase
YPD8_RS14655	COG0656	L-ascorbic acid biosynthetic process
YPD8_RS14675	COG1472	Belongs to the glycosyl hydrolase 3 family
YPD8_RS14690	COG3328	transposase activity
YPD8_RS14695	COG2850	peptidyl-arginine hydroxylation
YPD8_RS14745	COG3423	Transcriptional regulator
YPD8_RS14750	COG4953	penicillin-binding protein 1C
YPD8_RS14755	COG3328	transposase activity
YPD8_RS14760	COG3037	sugar-specific permease SgaT UlaA
YPD8_RS14770	COG0622	Phosphoesterase
YPD8_RS14780	COG1090	epimerase
YPD8_RS14785	COG4598	ABC transporter
YPD8_RS14790	COG4160	amino acid transport
YPD8_RS14795	COG4215	(ABC) transporter
YPD8_RS14800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS14810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPD8_RS14815	COG1286	toxin biosynthetic process
YPD8_RS14820	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPD8_RS14825	COG0285	dihydrofolate synthase activity
YPD8_RS14835	COG0586	Pfam SNARE associated Golgi protein
YPD8_RS14845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPD8_RS14865	COG0697	spore germination
YPD8_RS14880	COG1794	racemase activity, acting on amino acids and derivatives
YPD8_RS14885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPD8_RS14900	COG3101	peptidyl-lysine hydroxylation
YPD8_RS14905	COG0730	response to heat
YPD8_RS14935	COG2062	phosphohistidine phosphatase, SixA
YPD8_RS14950	COG3691	Protein conserved in bacteria
YPD8_RS14965	COG3088	subunit of a heme lyase
YPD8_RS14965	COG4235	cytochrome complex assembly
YPD8_RS14970	COG3088	subunit of a heme lyase
YPD8_RS14970	COG4235	cytochrome complex assembly
YPD8_RS14975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPD8_RS14980	COG1138	Cytochrome C-type biogenesis protein
YPD8_RS14990	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPD8_RS14995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPD8_RS15000	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPD8_RS15020	COG1704	LemA family
YPD8_RS15030	COG2824	Alkylphosphonate utilization operon protein PhnA
YPD8_RS15120	COG3188	usher protein
YPD8_RS15125	COG3328	transposase activity
YPD8_RS15130	COG3188	usher protein
YPD8_RS15135	COG3121	Chaperone
YPD8_RS15195	COG2951	lytic endotransglycosylase activity
YPD8_RS15230	COG0243	molybdopterin cofactor binding
YPD8_RS15235	COG0437	4 iron, 4 sulfur cluster binding
YPD8_RS15240	COG3302	dmso reductase anchor subunit
YPD8_RS15245	COG3381	protein complex oligomerization
YPD8_RS15275	COG3038	cytochrome b561
YPD8_RS15280	COG0436	Aminotransferase
YPD8_RS15305	COG0667	Aldo Keto reductase
YPD8_RS15320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPD8_RS15380	COG3530	Putative quorum-sensing-regulated virulence factor
YPD8_RS15395	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPD8_RS15405	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS15430	COG2205	protein histidine kinase activity
YPD8_RS15435	COG0745	RESPONSE REGULATOR receiver
YPD8_RS15440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPD8_RS15455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPD8_RS15475	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPD8_RS15485	COG3850	Histidine kinase
YPD8_RS15485	COG5002	protein histidine kinase activity
YPD8_RS15490	COG0745	RESPONSE REGULATOR receiver
YPD8_RS15505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPD8_RS15510	COG4208	sulfate ABC transporter
YPD8_RS15515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPD8_RS15520	COG4150	thiosulfate binding
YPD8_RS15530	COG1737	Transcriptional regulator
YPD8_RS15540	COG2731	YhcH YjgK YiaL family protein
YPD8_RS15550	COG4886	Leucine-rich repeat (LRR) protein
YPD8_RS15560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPD8_RS15565	COG2837	iron assimilation
YPD8_RS15575	COG3111	PFAM Bacterial OB fold (BOF) protein
YPD8_RS15620	COG3005	denitrification pathway
YPD8_RS15625	COG3043	anaerobic respiration
YPD8_RS15635	COG3062	negative regulation of establishment of protein localization
YPD8_RS15645	COG2197	response regulator
YPD8_RS15655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPD8_RS15665	COG1988	membrane-bound metal-dependent
YPD8_RS15670	COG0641	radical SAM
YPD8_RS15675	COG3119	arylsulfatase activity
YPD8_RS15680	COG3842	ATPase activity
YPD8_RS15685	COG1175	transmembrane transport
YPD8_RS15700	COG1393	Belongs to the ArsC family
YPD8_RS15710	COG1876	peptidase activity
YPD8_RS15730	COG2321	neutral zinc metallopeptidase
YPD8_RS15750	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPD8_RS15760	COG2716	regulation of RNA biosynthetic process
YPD8_RS15765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPD8_RS15785	COG0628	permease
YPD8_RS15790	COG4783	chaperone-mediated protein folding
YPD8_RS15795	COG1393	Belongs to the ArsC family
YPD8_RS15820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPD8_RS15830	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPD8_RS15835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPD8_RS15840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPD8_RS15845	COG4181	ATPase activity
YPD8_RS15850	COG2755	lipolytic protein G-D-S-L family
YPD8_RS15855	COG0300	oxidoreductase activity
YPD8_RS15860	COG3118	belongs to the thioredoxin family
YPD8_RS15865	COG0330	HflC and HflK could
YPD8_RS15870	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPD8_RS15875	COG0789	Transcriptional regulator
YPD8_RS15880	COG2217	Heavy metal translocating P-type atpase
YPD8_RS15885	COG3735	TraB family
YPD8_RS15890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPD8_RS15905	COG0737	Belongs to the 5'-nucleotidase family
YPD8_RS15910	COG0737	Belongs to the 5'-nucleotidase family
YPD8_RS15915	COG0737	Belongs to the 5'-nucleotidase family
YPD8_RS15920	COG2223	nitrite transmembrane transporter activity
YPD8_RS15925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPD8_RS15925	COG4651	solute:proton antiporter activity
YPD8_RS15930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPD8_RS15935	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPD8_RS15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPD8_RS16000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPD8_RS16025	COG0543	2 iron, 2 sulfur cluster binding
YPD8_RS16025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPD8_RS16055	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPD8_RS16080	COG3264	Mechanosensitive ion channel
YPD8_RS16080	COG1196	nuclear chromosome segregation
YPD8_RS16085	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPD8_RS16090	COG1309	transcriptional regulator
YPD8_RS16095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPD8_RS16100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPD8_RS16110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPD8_RS16130	COG3695	enzyme binding
YPD8_RS16135	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPD8_RS16140	COG1946	Acyl-CoA thioesterase
YPD8_RS16145	COG0004	ammonium transporteR
YPD8_RS16150	COG0347	Belongs to the P(II) protein family
YPD8_RS16155	COG1132	(ABC) transporter
YPD8_RS16160	COG1132	(ABC) transporter
YPD8_RS16165	COG1522	sequence-specific DNA binding
YPD8_RS16180	COG4533	DNA binding
YPD8_RS16190	COG0824	Thioesterase
YPD8_RS16195	COG1555	photosystem II stabilization
YPD8_RS16200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPD8_RS16205	COG0776	regulation of translation
YPD8_RS16210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPD8_RS16235	COG0271	Belongs to the BolA IbaG family
YPD8_RS16240	COG3056	Lipoprotein
YPD8_RS16245	COG2223	nitrite transmembrane transporter activity
YPD8_RS16255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPD8_RS16260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPD8_RS16265	COG1845	cytochrome c oxidase, subunit III
YPD8_RS16270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPD8_RS16280	COG2814	Major facilitator Superfamily
YPD8_RS16290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPD8_RS16295	COG0693	protein deglycase activity
YPD8_RS16315	COG0142	geranyltranstransferase activity
YPD8_RS16335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPD8_RS16340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPD8_RS16355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPD8_RS16355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPD8_RS16380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPD8_RS16385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPD8_RS16390	COG1862	Preprotein translocase
YPD8_RS16435	COG0366	Alpha amylase catalytic
YPD8_RS16450	COG0366	Alpha amylase catalytic
YPD8_RS16470	COG5002	protein histidine kinase activity
YPD8_RS16475	COG0745	RESPONSE REGULATOR receiver
YPD8_RS16485	COG0420	3'-5' exonuclease activity
YPD8_RS16490	COG0419	ATPase involved in DNA repair
YPD8_RS16495	COG1940	carbohydrate kinase activity
YPD8_RS16530	COG2226	methyltransferase
YPD8_RS16590	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPD8_RS16610	COG1477	protein flavinylation
YPD8_RS16630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPD8_RS16635	COG1805	sodium ion transport
YPD8_RS16645	COG3034	peptidoglycan biosynthetic process
YPD8_RS16650	COG0121	glutamine amidotransferase
YPD8_RS16660	COG1960	acyl-CoA dehydrogenase activity
YPD8_RS16670	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPD8_RS16690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPD8_RS16705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPD8_RS16715	COG0765	amino acid transport
YPD8_RS16755	COG2814	Major facilitator Superfamily
YPD8_RS16760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPD8_RS16770	COG1846	Transcriptional regulator
YPD8_RS16775	COG1566	PFAM secretion protein HlyD family protein
YPD8_RS16780	COG2814	Major facilitator Superfamily
YPD8_RS16790	COG3118	belongs to the thioredoxin family
YPD8_RS16795	COG3148	PFAM DTW domain containing protein
YPD8_RS16800	COG1042	CoA-binding domain protein
YPD8_RS16800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPD8_RS16800	COG0045	succinate-CoA ligase (ADP-forming) activity
YPD8_RS16805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPD8_RS16810	COG5544	Lipoprotein
YPD8_RS16850	COG0542	response to heat
YPD8_RS16860	COG0564	pseudouridine synthase activity
YPD8_RS16865	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPD8_RS16870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPD8_RS16885	COG1605	Chorismate mutase
YPD8_RS16885	COG0077	Prephenate dehydratase
YPD8_RS16900	COG0077	Prephenate dehydratase
YPD8_RS16900	COG1605	Chorismate mutase
YPD8_RS16905	COG1605	Chorismate mutase
YPD8_RS16905	COG0287	Prephenate dehydrogenase
YPD8_RS16910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPD8_RS16915	COG3279	Response regulator of the LytR AlgR family
YPD8_RS16920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPD8_RS16925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPD8_RS16930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPD8_RS16935	COG3137	Salt-induced outer membrane protein
YPD8_RS16970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPD8_RS16975	COG4137	Cytochrome C assembly protein
YPD8_RS16980	COG4536	flavin adenine dinucleotide binding
YPD8_RS17000	COG2918	glutathione biosynthetic process
YPD8_RS17010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPD8_RS17035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPD8_RS17080	COG3958	Transketolase
YPD8_RS17085	COG3959	Transketolase, thiamine diphosphate binding domain
YPD8_RS17090	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS17095	COG1129	ABC transporter
YPD8_RS17105	COG1879	ABC-type sugar transport system periplasmic component
YPD8_RS17115	COG3783	Cytochrome b(562)
YPD8_RS17120	COG3038	cytochrome b561
YPD8_RS17125	COG3381	protein complex oligomerization
YPD8_RS17130	COG3302	dmso reductase anchor subunit
YPD8_RS17135	COG0437	4 iron, 4 sulfur cluster binding
YPD8_RS17140	COG0243	molybdopterin cofactor binding
YPD8_RS17145	COG0235	Class ii aldolase
YPD8_RS17150	COG1349	DNA-binding transcription factor activity
YPD8_RS17165	COG1129	ABC transporter
YPD8_RS17170	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS17175	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS17180	COG3623	hexulose-6-phosphate isomerase
YPD8_RS17185	COG1070	Carbohydrate kinase
YPD8_RS17190	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPD8_RS17190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPD8_RS17200	COG0024	Methionine aminopeptidase
YPD8_RS17220	COG4771	TonB-dependent receptor
YPD8_RS17230	COG1858	cytochrome C peroxidase
YPD8_RS17235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS17255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPD8_RS17270	COG2376	Dihydroxyacetone kinase
YPD8_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
YPD8_RS17280	COG1063	alcohol dehydrogenase
YPD8_RS17285	COG0698	ribose 5-phosphate isomerase
YPD8_RS17300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPD8_RS17345	COG0529	Catalyzes the synthesis of activated sulfate
YPD8_RS17395	COG0720	synthase
YPD8_RS17400	COG0602	queuosine metabolic process
YPD8_RS17420	COG3956	TIGRFAM MazG family protein
YPD8_RS17430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPD8_RS17435	COG3850	Histidine kinase
YPD8_RS17435	COG4999	Histidine kinase
YPD8_RS17435	COG3437	response regulator, receiver
YPD8_RS17435	COG2205	protein histidine kinase activity
YPD8_RS17440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPD8_RS17460	COG2860	membrane
YPD8_RS17480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPD8_RS17485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPD8_RS17495	COG1120	ATPase activity
YPD8_RS17505	COG1643	Atp-dependent helicase
YPD8_RS17510	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPD8_RS17535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPD8_RS17560	COG0842	Transport permease protein
YPD8_RS17565	COG1131	(ABC) transporter
YPD8_RS17570	COG0288	reversible hydration of carbon dioxide
YPD8_RS17575	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPD8_RS17600	COG0697	spore germination
YPD8_RS17610	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPD8_RS17625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPD8_RS17630	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPD8_RS17635	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPD8_RS17640	COG2186	Transcriptional regulator
YPD8_RS17645	COG1113	amino acid transport
YPD8_RS17650	COG3725	Membrane protein required for beta-lactamase induction
YPD8_RS17655	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPD8_RS17665	COG4969	Belongs to the N-Me-Phe pilin family
YPD8_RS17670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPD8_RS17675	COG1459	type II secretion system
YPD8_RS17730	COG0582	viral genome integration into host DNA
YPD8_RS17740	COG0795	lipopolysaccharide-transporting ATPase activity
YPD8_RS17745	COG0795	lipopolysaccharide-transporting ATPase activity
YPD8_RS17755	COG2927	DNA polymerase III (CHI subunit)
YPD8_RS17760	COG0525	valine-tRNA ligase activity
YPD8_RS17770	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPD8_RS17780	COG2731	YhcH YjgK YiaL family protein
YPD8_RS17790	COG0601	transmembrane transport
YPD8_RS17795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPD8_RS17800	COG0444	Belongs to the ABC transporter superfamily
YPD8_RS17805	COG4608	Belongs to the ABC transporter superfamily
YPD8_RS17820	COG2188	Transcriptional regulator
YPD8_RS17825	COG3624	Phosphonate C-P lyase system protein PhnG
YPD8_RS17830	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPD8_RS17835	COG3626	phosphonate metabolism
YPD8_RS17840	COG3627	carbon phosphorus lyase activity
YPD8_RS17845	COG4107	phosphonate C-P lyase system protein PhnK
YPD8_RS17850	COG4778	phosphonate C-P lyase system protein PhnL
YPD8_RS17855	COG3454	Phosphonate metabolism
YPD8_RS17860	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPD8_RS17865	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPD8_RS17870	COG0702	epimerase
YPD8_RS17885	COG3842	ATPase activity
YPD8_RS17890	COG0395	ABC-type sugar transport system, permease component
YPD8_RS17895	COG1175	transmembrane transport
YPD8_RS17900	COG1653	transport
YPD8_RS17920	COG3153	acetyltransferase
YPD8_RS17925	COG3154	lipid carrier protein
YPD8_RS17935	COG0826	peptidase U32
YPD8_RS17940	COG0826	peptidase U32
YPD8_RS17950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPD8_RS17960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPD8_RS17980	COG0513	Belongs to the DEAD box helicase family
YPD8_RS17995	COG2801	Transposase and inactivated derivatives
YPD8_RS18025	COG0195	Participates in both transcription termination and antitermination
YPD8_RS18045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPD8_RS18055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPD8_RS18070	COG1534	Rna-binding protein
YPD8_RS18080	COG2027	D-alanyl-D-alanine carboxypeptidase
YPD8_RS18085	COG0745	RESPONSE REGULATOR receiver
YPD8_RS18090	COG0642	Histidine kinase
YPD8_RS18100	COG0697	spore germination
YPD8_RS18115	COG0142	geranyltranstransferase activity
YPD8_RS18125	COG3423	Transcriptional regulator
YPD8_RS18150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPD8_RS18155	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YPD8_RS18160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPD8_RS18165	COG2105	PFAM AIG2 family protein
YPD8_RS18170	COG2911	Protein conserved in bacteria
YPD8_RS18175	COG0729	surface antigen
YPD8_RS18195	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPD8_RS18205	COG0737	Belongs to the 5'-nucleotidase family
YPD8_RS18215	COG0545	Peptidyl-prolyl cis-trans isomerase
YPD8_RS18220	COG3061	Opacity-associated protein A
YPD8_RS18245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPD8_RS18255	COG0360	Binds together with S18 to 16S ribosomal RNA
YPD8_RS18265	COG1073	alpha beta
YPD8_RS18280	COG0435	Glutathione S-transferase
YPD8_RS18285	COG0583	DNA-binding transcription factor activity
YPD8_RS18290	COG1741	Belongs to the pirin family
YPD8_RS18295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPD8_RS18315	COG2823	Periplasmic or secreted lipoprotein
YPD8_RS18325	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPD8_RS18335	COG2198	Histidine kinase
YPD8_RS18335	COG0784	Response regulator, receiver
YPD8_RS18335	COG5002	protein histidine kinase activity
YPD8_RS18345	COG1242	4 iron, 4 sulfur cluster binding
YPD8_RS18350	COG0067	glutamate synthase
YPD8_RS18350	COG0069	glutamate synthase activity
YPD8_RS18350	COG0070	glutamate synthase
YPD8_RS18355	COG0493	'glutamate synthase
YPD8_RS18365	COG2969	positive regulation of protein catabolic process
YPD8_RS18370	COG0625	glutathione transferase activity
YPD8_RS18395	COG3105	Protein conserved in bacteria
YPD8_RS18400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPD8_RS18410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPD8_RS18420	COG5007	Belongs to the BolA IbaG family
YPD8_RS18425	COG3113	response to antibiotic
YPD8_RS18430	COG2854	intermembrane phospholipid transfer
YPD8_RS18435	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPD8_RS18440	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPD8_RS18445	COG1127	ABC transporter
YPD8_RS18450	COG0530	calcium, potassium:sodium antiporter activity
YPD8_RS18455	COG0517	IMP dehydrogenase activity
YPD8_RS18455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPD8_RS18460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPD8_RS18465	COG3117	lipopolysaccharide transmembrane transporter activity
YPD8_RS18470	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPD8_RS18475	COG1137	ATPase activity
YPD8_RS18480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPD8_RS18500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS18525	COG1609	Transcriptional regulator
YPD8_RS18530	COG1263	PTS System
YPD8_RS18530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPD8_RS18535	COG0366	Alpha amylase catalytic
YPD8_RS18540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPD8_RS18545	COG3783	Cytochrome b(562)
YPD8_RS18555	COG0312	modulator of DNA gyrase
YPD8_RS18565	COG2732	(Barnase) inhibitor
YPD8_RS18580	COG1012	belongs to the aldehyde dehydrogenase family
YPD8_RS18600	COG0583	DNA-binding transcription factor activity
YPD8_RS18660	COG0312	modulator of DNA gyrase
YPD8_RS18665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPD8_RS18675	COG1530	ribonuclease E activity
YPD8_RS18680	COG0424	maF-like protein
YPD8_RS18685	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPD8_RS18690	COG1792	Involved in formation and maintenance of cell shape
YPD8_RS18695	COG1077	Cell shape determining protein MreB Mrl
YPD8_RS18700	COG2200	EAL domain
YPD8_RS18700	COG2199	diguanylate cyclase activity
YPD8_RS18705	COG0604	alcohol dehydrogenase
YPD8_RS18710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPD8_RS18725	COG0511	ligase activity, forming carbon-carbon bonds
YPD8_RS18730	COG0439	Biotin carboxylase
YPD8_RS18735	COG3924	membrane
YPD8_RS18740	COG4145	pantothenate transmembrane transporter activity
YPD8_RS18750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPD8_RS18755	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPD8_RS18775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPD8_RS18785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPD8_RS18790	COG3133	Outer membrane lipoprotein
YPD8_RS18800	COG1278	Cold shock
YPD8_RS18805	COG1278	Cold shock
YPD8_RS18830	COG0625	glutathione transferase activity
YPD8_RS18840	COG1069	ribulokinase activity
YPD8_RS18850	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS18855	COG1129	ABC transporter
YPD8_RS18865	COG1560	Kdo2-lipid A biosynthetic process
YPD8_RS18875	COG0025	NhaP-type Na H and K H
YPD8_RS18880	COG2252	PERMEase
YPD8_RS18885	COG3077	Addiction module antitoxin, RelB DinJ family
YPD8_RS18895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPD8_RS18905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPD8_RS18910	COG0431	NADPH-dependent FMN reductase
YPD8_RS18915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPD8_RS18920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPD8_RS18925	COG1869	D-ribose catabolic process
YPD8_RS18930	COG2207	Transcriptional regulator
YPD8_RS18930	COG1917	Cupin 2, conserved barrel domain protein
YPD8_RS18935	COG0673	inositol 2-dehydrogenase activity
YPD8_RS18950	COG3209	COG3209 Rhs family protein
YPD8_RS18960	COG3501	Rhs element vgr protein
YPD8_RS19005	COG3501	Rhs element vgr protein
YPD8_RS19080	COG2801	Transposase and inactivated derivatives
YPD8_RS19140	COG1175	transmembrane transport
YPD8_RS19145	COG3833	ABC-type maltose transport systems, permease component
YPD8_RS19160	COG0527	aspartate kinase activity
YPD8_RS19180	COG1414	Transcriptional regulator
YPD8_RS19185	COG1414	Transcriptional regulator
YPD8_RS19195	COG2224	Isocitrate lyase
YPD8_RS19200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPD8_RS19255	COG0151	Belongs to the GarS family
YPD8_RS19275	COG1515	deoxyribonuclease V activity
YPD8_RS19315	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPD8_RS19380	COG0250	Participates in transcription elongation, termination and antitermination
YPD8_RS19440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YPD8_RS19475	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPD8_RS19480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPD8_RS19485	COG1739	Uncharacterized protein family UPF0029
YPD8_RS19495	COG1739	Uncharacterized protein family UPF0029
YPD8_RS19520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YPD8_RS19555	COG0805	protein transport
YPD8_RS19565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPD8_RS19585	COG1322	Protein conserved in bacteria
YPD8_RS19590	COG0586	Pfam SNARE associated Golgi protein
YPD8_RS19595	COG1966	Carbon starvation protein
YPD8_RS19610	COG0412	Dienelactone hydrolase
YPD8_RS19620	COG0583	DNA-binding transcription factor activity
YPD8_RS19625	COG0697	spore germination
YPD8_RS19630	COG0679	Auxin Efflux Carrier
YPD8_RS19635	COG0584	glycerophosphoryl diester phosphodiesterase
YPD8_RS19695	COG0410	ABC transporter
YPD8_RS19705	COG4177	L-phenylalanine transmembrane transporter activity
YPD8_RS19715	COG0683	leucine binding
YPD8_RS19740	COG2177	Part of the ABC transporter FtsEX involved in
YPD8_RS19745	COG2884	Cell division ATP-binding protein ftsE
YPD8_RS19750	COG0552	protein localization to endoplasmic reticulum
YPD8_RS19750	COG0552	protein localization to endoplasmic reticulum
YPD8_RS19760	COG0742	ribosomal rna small subunit methyltransferase
YPD8_RS19765	COG3776	membrane
YPD8_RS19780	COG3714	YhhN family
YPD8_RS19795	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPD8_RS19805	COG0247	lactate metabolic process
YPD8_RS19815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPD8_RS19825	COG0584	glycerophosphoryl diester phosphodiesterase
YPD8_RS19835	COG0561	phosphatase activity
YPD8_RS19840	COG2267	carboxylic ester hydrolase activity
YPD8_RS19845	COG1280	lysine exporter protein (LysE YggA)
YPD8_RS19850	COG1280	lysine exporter protein (LysE YggA)
YPD8_RS19855	COG0514	ATP-dependent DNA helicase (RecQ)
YPD8_RS19860	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPD8_RS19865	COG2050	protein possibly involved in aromatic compounds catabolism
YPD8_RS19880	COG5564	TIM-barrel signal transduction protein
YPD8_RS19885	COG5441	Belongs to the UPF0261 family
YPD8_RS19895	COG0210	DNA helicase
YPD8_RS19900	COG1011	Hydrolase
YPD8_RS19905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPD8_RS19910	COG3159	Protein conserved in bacteria
YPD8_RS19930	COG3072	Adenylate cyclase
YPD8_RS19945	COG1587	Uroporphyrinogen-III synthase
YPD8_RS19950	COG2959	enzyme of heme biosynthesis
YPD8_RS19955	COG3071	HemY protein
YPD8_RS19990	COG1113	amino acid transport
YPD8_RS20010	COG2244	polysaccharide biosynthetic process
YPD8_RS20015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPD8_RS20020	COG0456	acetyltransferase
YPD8_RS20025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPD8_RS20030	COG1088	dTDP-glucose 4,6-dehydratase activity
YPD8_RS20035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPD8_RS20040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPD8_RS20045	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPD8_RS20055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPD8_RS20060	COG3118	belongs to the thioredoxin family
YPD8_RS20090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPD8_RS20115	COG3121	Chaperone
YPD8_RS20130	COG3121	Chaperone
YPD8_RS20170	COG0583	DNA-binding transcription factor activity
YPD8_RS20215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPD8_RS20220	COG3978	acetolactate synthase activity
YPD8_RS20235	COG3085	chromosome segregation
YPD8_RS20245	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS20250	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS20255	COG1129	ABC transporter
YPD8_RS20260	COG1879	ABC-type sugar transport system periplasmic component
YPD8_RS20345	COG0678	peroxiredoxin activity
YPD8_RS20345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPD8_RS20350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPD8_RS20375	COG1629	transport
YPD8_RS20395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPD8_RS20415	COG2801	Transposase and inactivated derivatives
YPD8_RS20435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPD8_RS20440	COG0058	SHG alpha-glucan phosphorylase activity
YPD8_RS20465	COG3275	phosphorelay sensor kinase activity
YPD8_RS20495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPD8_RS20500	COG2095	MarC family integral membrane protein
YPD8_RS20520	COG3265	gluconokinase activity
YPD8_RS20530	COG1609	Transcriptional regulator
YPD8_RS20535	COG1741	Belongs to the pirin family
YPD8_RS20555	COG0191	fructose-bisphosphate aldolase activity
YPD8_RS20570	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPD8_RS20585	COG2081	HI0933 family
YPD8_RS20590	COG0306	phosphate transporter
YPD8_RS20610	COG0589	response to stress
YPD8_RS20630	COG0339	signal peptide processing
YPD8_RS20635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPD8_RS20645	COG3835	regulator
YPD8_RS20650	COG2610	gluconate transmembrane transporter activity
YPD8_RS20655	COG1929	Belongs to the glycerate kinase type-1 family
YPD8_RS20685	COG2134	cdp-diacylglycerol pyrophosphatase
YPD8_RS20690	COG2982	Protein involved in outer membrane biogenesis
YPD8_RS20695	COG2200	EAL domain
YPD8_RS20700	COG1942	4-Oxalocrotonate Tautomerase
YPD8_RS20705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPD8_RS20710	COG0612	Peptidase, M16
YPD8_RS20730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPD8_RS20735	COG2199	diguanylate cyclase activity
YPD8_RS20735	COG2200	EAL domain
YPD8_RS20740	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPD8_RS20745	COG4608	Belongs to the ABC transporter superfamily
YPD8_RS20755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPD8_RS20760	COG0601	transmembrane transport
YPD8_RS20765	COG0747	negative chemotaxis
YPD8_RS20775	COG2831	hemolysin activation secretion protein
YPD8_RS20790	COG2271	Major facilitator Superfamily
YPD8_RS20815	COG3851	Histidine kinase
YPD8_RS20820	COG2197	response regulator
YPD8_RS20825	COG2194	sulfuric ester hydrolase activity
YPD8_RS20845	COG2986	histidine ammonia-lyase
YPD8_RS20875	COG4607	ABC-type enterochelin transport system periplasmic component
YPD8_RS20885	COG4605	iron ion homeostasis
YPD8_RS20890	COG4604	ABC transporter, ATP-binding protein
YPD8_RS20930	COG0582	viral genome integration into host DNA
YPD8_RS20935	COG2207	Transcriptional regulator
YPD8_RS20935	COG1609	Transcriptional regulator
YPD8_RS20940	COG4214	carbohydrate transport
YPD8_RS20950	COG4213	ABC transporter substrate-binding protein
YPD8_RS20960	COG1070	Carbohydrate kinase
YPD8_RS20970	COG3121	Chaperone
YPD8_RS20990	COG3274	enterobacterial common antigen metabolic process
YPD8_RS21005	COG2801	Transposase and inactivated derivatives
YPD8_RS21040	COG3276	selenocysteine insertion sequence binding
YPD8_RS21055	COG2864	formate dehydrogenase
YPD8_RS21060	COG0437	4 iron, 4 sulfur cluster binding
YPD8_RS21065	COG3383	formate dehydrogenase (NAD+) activity
YPD8_RS21065	COG0243	molybdopterin cofactor binding
YPD8_RS21070	COG0243	molybdopterin cofactor binding
YPD8_RS21070	COG3383	formate dehydrogenase (NAD+) activity
YPD8_RS21080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPD8_RS21105	COG3722	fumarate hydratase activity
YPD8_RS21115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPD8_RS21115	COG2213	PTS system mannitol-specific
YPD8_RS21135	COG2818	Glycosylase
YPD8_RS21145	COG2885	chlorophyll binding
YPD8_RS21160	COG0366	Alpha amylase catalytic
YPD8_RS21170	COG3977	Valine--pyruvate aminotransferase
YPD8_RS21190	COG5645	(Lipo)protein
YPD8_RS21195	COG0823	Involved in the tonB-independent uptake of proteins
YPD8_RS21200	COG0823	Involved in the tonB-independent uptake of proteins
YPD8_RS21205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPD8_RS21210	COG2423	ornithine cyclodeaminase activity
YPD8_RS21220	COG2801	Transposase and inactivated derivatives
YPD8_RS21225	COG0561	phosphatase activity
YPD8_RS21230	COG0187	DNA topoisomerase II activity
YPD8_RS21245	COG0592	DNA-directed DNA polymerase activity
YPD8_RS21255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPD8_RS21265	COG0706	membrane insertase activity
YPD8_RS21290	COG2252	PERMEase
YPD8_RS21295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPD8_RS21300	COG0765	amino acid transport
YPD8_RS21305	COG0765	amino acid transport
YPD8_RS21310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPD8_RS21320	COG0704	Plays a role in the regulation of phosphate uptake
YPD8_RS21330	COG0581	inorganic phosphate transmembrane transporter activity
YPD8_RS21335	COG0573	inorganic phosphate transmembrane transporter activity
YPD8_RS21340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPD8_RS21395	COG3312	ion transport
YPD8_RS21485	COG0477	Major facilitator Superfamily
YPD8_RS21685	COG0456	acetyltransferase
YPD8_RS21800	COG1309	transcriptional regulator
YPD8_RS22140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPD8_RS22150	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPD8_RS22180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance