locus-tag	class	description
CH61_RS00250	COG2213	PTS system mannitol-specific
CH61_RS00250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS00300	COG0840	transmembrane signaling receptor activity
CH61_RS00455	COG1070	Carbohydrate kinase
CH61_RS00485	COG0706	membrane insertase activity
CH61_RS00780	COG0706	membrane insertase activity
CH61_RS00790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CH61_RS00800	COG0592	DNA-directed DNA polymerase activity
CH61_RS00810	COG0187	DNA topoisomerase II activity
CH61_RS00815	COG0561	phosphatase activity
CH61_RS00820	COG2801	Transposase and inactivated derivatives
CH61_RS00830	COG2423	ornithine cyclodeaminase activity
CH61_RS00835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CH61_RS00840	COG0823	Involved in the tonB-independent uptake of proteins
CH61_RS00845	COG0823	Involved in the tonB-independent uptake of proteins
CH61_RS00850	COG5645	(Lipo)protein
CH61_RS00870	COG3977	Valine--pyruvate aminotransferase
CH61_RS00880	COG0366	Alpha amylase catalytic
CH61_RS00895	COG2885	chlorophyll binding
CH61_RS00905	COG2818	Glycosylase
CH61_RS00925	COG2213	PTS system mannitol-specific
CH61_RS00925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS00935	COG3722	fumarate hydratase activity
CH61_RS00960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CH61_RS00970	COG0243	molybdopterin cofactor binding
CH61_RS00970	COG3383	formate dehydrogenase (NAD+) activity
CH61_RS00975	COG0243	molybdopterin cofactor binding
CH61_RS00975	COG3383	formate dehydrogenase (NAD+) activity
CH61_RS00980	COG0437	4 iron, 4 sulfur cluster binding
CH61_RS00985	COG2864	formate dehydrogenase
CH61_RS01000	COG3276	selenocysteine insertion sequence binding
CH61_RS01005	COG3276	selenocysteine insertion sequence binding
CH61_RS01040	COG2801	Transposase and inactivated derivatives
CH61_RS01055	COG3274	enterobacterial common antigen metabolic process
CH61_RS01075	COG3121	Chaperone
CH61_RS01085	COG1070	Carbohydrate kinase
CH61_RS01095	COG4213	ABC transporter substrate-binding protein
CH61_RS01105	COG4214	carbohydrate transport
CH61_RS01110	COG1609	Transcriptional regulator
CH61_RS01110	COG2207	Transcriptional regulator
CH61_RS01115	COG0582	viral genome integration into host DNA
CH61_RS01155	COG4604	ABC transporter, ATP-binding protein
CH61_RS01160	COG4605	iron ion homeostasis
CH61_RS01170	COG4607	ABC-type enterochelin transport system periplasmic component
CH61_RS01200	COG2986	histidine ammonia-lyase
CH61_RS01215	COG2194	sulfuric ester hydrolase activity
CH61_RS01220	COG2197	response regulator
CH61_RS01225	COG3851	Histidine kinase
CH61_RS01250	COG2271	Major facilitator Superfamily
CH61_RS01265	COG2831	hemolysin activation secretion protein
CH61_RS01275	COG0747	negative chemotaxis
CH61_RS01280	COG0601	transmembrane transport
CH61_RS01285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_RS01290	COG0444	Belongs to the ABC transporter superfamily
CH61_RS01295	COG4608	Belongs to the ABC transporter superfamily
CH61_RS01300	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CH61_RS01305	COG2200	EAL domain
CH61_RS01305	COG2199	diguanylate cyclase activity
CH61_RS01310	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH61_RS01330	COG0612	Peptidase, M16
CH61_RS01335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_RS01340	COG1942	4-Oxalocrotonate Tautomerase
CH61_RS01345	COG2200	EAL domain
CH61_RS01350	COG2982	Protein involved in outer membrane biogenesis
CH61_RS01355	COG2134	cdp-diacylglycerol pyrophosphatase
CH61_RS01360	COG1295	ribonuclease BN
CH61_RS01385	COG1929	Belongs to the glycerate kinase type-1 family
CH61_RS01390	COG2610	gluconate transmembrane transporter activity
CH61_RS01395	COG3835	regulator
CH61_RS01400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH61_RS01405	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CH61_RS01410	COG0339	signal peptide processing
CH61_RS01430	COG0589	response to stress
CH61_RS01450	COG0306	phosphate transporter
CH61_RS01455	COG2081	HI0933 family
CH61_RS01470	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS01485	COG0191	fructose-bisphosphate aldolase activity
CH61_RS01505	COG1741	Belongs to the pirin family
CH61_RS01510	COG1609	Transcriptional regulator
CH61_RS01515	COG2610	gluconate transmembrane transporter activity
CH61_RS01520	COG3265	gluconokinase activity
CH61_RS01540	COG2095	MarC family integral membrane protein
CH61_RS01545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH61_RS01575	COG3275	phosphorelay sensor kinase activity
CH61_RS01600	COG0058	SHG alpha-glucan phosphorylase activity
CH61_RS01605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH61_RS01625	COG2801	Transposase and inactivated derivatives
CH61_RS01655	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CH61_RS01675	COG1629	transport
CH61_RS01700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH61_RS01705	COG0678	peroxiredoxin activity
CH61_RS01705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH61_RS01785	COG1879	ABC-type sugar transport system periplasmic component
CH61_RS01790	COG1129	ABC transporter
CH61_RS01795	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS01800	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS01810	COG3085	chromosome segregation
CH61_RS01825	COG3978	acetolactate synthase activity
CH61_RS01830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH61_RS01875	COG0583	DNA-binding transcription factor activity
CH61_RS01915	COG3121	Chaperone
CH61_RS01930	COG3121	Chaperone
CH61_RS01945	COG3328	transposase activity
CH61_RS01955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH61_RS01985	COG3118	belongs to the thioredoxin family
CH61_RS01990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CH61_RS01995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CH61_RS02000	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH61_RS02005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CH61_RS02010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CH61_RS02015	COG1088	dTDP-glucose 4,6-dehydratase activity
CH61_RS02020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CH61_RS02025	COG0456	acetyltransferase
CH61_RS02030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CH61_RS02035	COG2244	polysaccharide biosynthetic process
CH61_RS02055	COG1113	amino acid transport
CH61_RS02085	COG3071	HemY protein
CH61_RS02090	COG2959	enzyme of heme biosynthesis
CH61_RS02095	COG1587	Uroporphyrinogen-III synthase
CH61_RS02105	COG3072	Adenylate cyclase
CH61_RS02125	COG3159	Protein conserved in bacteria
CH61_RS02130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CH61_RS02135	COG1011	Hydrolase
CH61_RS02140	COG0210	DNA helicase
CH61_RS02150	COG5441	Belongs to the UPF0261 family
CH61_RS02155	COG5564	TIM-barrel signal transduction protein
CH61_RS02170	COG2050	protein possibly involved in aromatic compounds catabolism
CH61_RS02175	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
CH61_RS02180	COG0514	ATP-dependent DNA helicase (RecQ)
CH61_RS02185	COG1280	lysine exporter protein (LysE YggA)
CH61_RS02190	COG1280	lysine exporter protein (LysE YggA)
CH61_RS02195	COG2267	carboxylic ester hydrolase activity
CH61_RS02200	COG0561	phosphatase activity
CH61_RS02210	COG0584	glycerophosphoryl diester phosphodiesterase
CH61_RS02220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CH61_RS02230	COG0247	lactate metabolic process
CH61_RS02240	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CH61_RS02255	COG3714	YhhN family
CH61_RS02270	COG3776	membrane
CH61_RS02275	COG0742	ribosomal rna small subunit methyltransferase
CH61_RS02285	COG0552	protein localization to endoplasmic reticulum
CH61_RS02285	COG0552	protein localization to endoplasmic reticulum
CH61_RS02290	COG2884	Cell division ATP-binding protein ftsE
CH61_RS02295	COG2177	Part of the ABC transporter FtsEX involved in
CH61_RS02320	COG0683	leucine binding
CH61_RS02330	COG4177	L-phenylalanine transmembrane transporter activity
CH61_RS02340	COG0410	ABC transporter
CH61_RS02400	COG0584	glycerophosphoryl diester phosphodiesterase
CH61_RS02405	COG0679	Auxin Efflux Carrier
CH61_RS02410	COG0697	spore germination
CH61_RS02415	COG0583	DNA-binding transcription factor activity
CH61_RS02425	COG0412	Dienelactone hydrolase
CH61_RS02440	COG1966	Carbon starvation protein
CH61_RS02445	COG0586	Pfam SNARE associated Golgi protein
CH61_RS02450	COG1322	Protein conserved in bacteria
CH61_RS02470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH61_RS02480	COG0805	protein transport
CH61_RS02515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CH61_RS02540	COG1739	Uncharacterized protein family UPF0029
CH61_RS02550	COG1739	Uncharacterized protein family UPF0029
CH61_RS02555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CH61_RS02560	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
CH61_RS02595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CH61_RS02660	COG0250	Participates in transcription elongation, termination and antitermination
CH61_RS02715	COG2022	thiamine diphosphate biosynthetic process
CH61_RS02725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CH61_RS02765	COG1515	deoxyribonuclease V activity
CH61_RS02785	COG0151	Belongs to the GarS family
CH61_RS02845	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CH61_RS02850	COG2224	Isocitrate lyase
CH61_RS02860	COG1414	Transcriptional regulator
CH61_RS02865	COG1414	Transcriptional regulator
CH61_RS02885	COG0527	aspartate kinase activity
CH61_RS02900	COG3833	ABC-type maltose transport systems, permease component
CH61_RS02905	COG1175	transmembrane transport
CH61_RS03050	COG3501	Rhs element vgr protein
CH61_RS03095	COG3501	Rhs element vgr protein
CH61_RS03105	COG3209	COG3209 Rhs family protein
CH61_RS03120	COG0673	inositol 2-dehydrogenase activity
CH61_RS03125	COG1917	Cupin 2, conserved barrel domain protein
CH61_RS03125	COG2207	Transcriptional regulator
CH61_RS03130	COG1869	D-ribose catabolic process
CH61_RS03135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_RS03140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CH61_RS03145	COG0431	NADPH-dependent FMN reductase
CH61_RS03150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CH61_RS03160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH61_RS03170	COG3077	Addiction module antitoxin, RelB DinJ family
CH61_RS03175	COG2252	PERMEase
CH61_RS03180	COG0025	NhaP-type Na H and K H
CH61_RS03190	COG1560	Kdo2-lipid A biosynthetic process
CH61_RS03200	COG1129	ABC transporter
CH61_RS03205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS03215	COG1069	ribulokinase activity
CH61_RS03225	COG0625	glutathione transferase activity
CH61_RS03250	COG1278	Cold shock
CH61_RS03255	COG1278	Cold shock
CH61_RS03265	COG3133	Outer membrane lipoprotein
CH61_RS03270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH61_RS03280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH61_RS03305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CH61_RS03310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH61_RS03320	COG4145	pantothenate transmembrane transporter activity
CH61_RS03325	COG3924	membrane
CH61_RS03330	COG0439	Biotin carboxylase
CH61_RS03335	COG0511	ligase activity, forming carbon-carbon bonds
CH61_RS03350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CH61_RS03355	COG0604	alcohol dehydrogenase
CH61_RS03360	COG2200	EAL domain
CH61_RS03360	COG2199	diguanylate cyclase activity
CH61_RS03365	COG1077	Cell shape determining protein MreB Mrl
CH61_RS03370	COG1792	Involved in formation and maintenance of cell shape
CH61_RS03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CH61_RS03380	COG0424	maF-like protein
CH61_RS03385	COG1530	ribonuclease E activity
CH61_RS03390	COG3164	Protein of unknown function
CH61_RS03395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH61_RS03400	COG0312	modulator of DNA gyrase
CH61_RS03460	COG0583	DNA-binding transcription factor activity
CH61_RS03480	COG1012	belongs to the aldehyde dehydrogenase family
CH61_RS03495	COG2732	(Barnase) inhibitor
CH61_RS03505	COG0312	modulator of DNA gyrase
CH61_RS03515	COG3783	Cytochrome b(562)
CH61_RS03520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH61_RS03525	COG0366	Alpha amylase catalytic
CH61_RS03530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_RS03530	COG1263	PTS System
CH61_RS03535	COG1609	Transcriptional regulator
CH61_RS03580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS03600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CH61_RS03605	COG1137	ATPase activity
CH61_RS03610	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CH61_RS03615	COG3117	lipopolysaccharide transmembrane transporter activity
CH61_RS03620	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CH61_RS03625	COG0517	IMP dehydrogenase activity
CH61_RS03625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CH61_RS03630	COG0530	calcium, potassium:sodium antiporter activity
CH61_RS03635	COG1127	ABC transporter
CH61_RS03640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CH61_RS03645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH61_RS03650	COG2854	intermembrane phospholipid transfer
CH61_RS03655	COG3113	response to antibiotic
CH61_RS03660	COG5007	Belongs to the BolA IbaG family
CH61_RS03670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH61_RS03680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH61_RS03685	COG3105	Protein conserved in bacteria
CH61_RS03690	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CH61_RS03710	COG0625	glutathione transferase activity
CH61_RS03715	COG2969	positive regulation of protein catabolic process
CH61_RS03725	COG0493	'glutamate synthase
CH61_RS03730	COG0069	glutamate synthase activity
CH61_RS03730	COG0067	glutamate synthase
CH61_RS03730	COG0070	glutamate synthase
CH61_RS03735	COG1242	4 iron, 4 sulfur cluster binding
CH61_RS03745	COG2198	Histidine kinase
CH61_RS03745	COG0784	Response regulator, receiver
CH61_RS03745	COG5002	protein histidine kinase activity
CH61_RS03755	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CH61_RS03765	COG2823	Periplasmic or secreted lipoprotein
CH61_RS03785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CH61_RS03790	COG1741	Belongs to the pirin family
CH61_RS03795	COG0583	DNA-binding transcription factor activity
CH61_RS03800	COG0435	Glutathione S-transferase
CH61_RS03820	COG1073	alpha beta
CH61_RS03830	COG0360	Binds together with S18 to 16S ribosomal RNA
CH61_RS03840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CH61_RS03865	COG3061	Opacity-associated protein A
CH61_RS03870	COG0545	Peptidyl-prolyl cis-trans isomerase
CH61_RS03880	COG0737	Belongs to the 5'-nucleotidase family
CH61_RS03890	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CH61_RS03900	COG1253	flavin adenine dinucleotide binding
CH61_RS03910	COG0729	surface antigen
CH61_RS03915	COG2911	Protein conserved in bacteria
CH61_RS03920	COG2105	PFAM AIG2 family protein
CH61_RS03925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CH61_RS03930	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CH61_RS03935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CH61_RS03960	COG3423	Transcriptional regulator
CH61_RS03970	COG0142	geranyltranstransferase activity
CH61_RS03985	COG0697	spore germination
CH61_RS03995	COG0642	Histidine kinase
CH61_RS04000	COG0745	RESPONSE REGULATOR receiver
CH61_RS04005	COG2027	D-alanyl-D-alanine carboxypeptidase
CH61_RS04015	COG1534	Rna-binding protein
CH61_RS04030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CH61_RS04040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CH61_RS04060	COG0195	Participates in both transcription termination and antitermination
CH61_RS04090	COG2801	Transposase and inactivated derivatives
CH61_RS04105	COG0513	Belongs to the DEAD box helicase family
CH61_RS04125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CH61_RS04135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_RS04145	COG0826	peptidase U32
CH61_RS04150	COG0826	peptidase U32
CH61_RS04160	COG3154	lipid carrier protein
CH61_RS04165	COG3153	acetyltransferase
CH61_RS04185	COG1653	transport
CH61_RS04190	COG1175	transmembrane transport
CH61_RS04195	COG0395	ABC-type sugar transport system, permease component
CH61_RS04200	COG3842	ATPase activity
CH61_RS04215	COG0702	epimerase
CH61_RS04220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CH61_RS04225	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CH61_RS04230	COG3454	Phosphonate metabolism
CH61_RS04235	COG4778	phosphonate C-P lyase system protein PhnL
CH61_RS04240	COG4107	phosphonate C-P lyase system protein PhnK
CH61_RS04245	COG3627	carbon phosphorus lyase activity
CH61_RS04250	COG3626	phosphonate metabolism
CH61_RS04255	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CH61_RS04260	COG3624	Phosphonate C-P lyase system protein PhnG
CH61_RS04265	COG2188	Transcriptional regulator
CH61_RS04280	COG4608	Belongs to the ABC transporter superfamily
CH61_RS04285	COG0444	Belongs to the ABC transporter superfamily
CH61_RS04290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_RS04295	COG0601	transmembrane transport
CH61_RS04305	COG2731	YhcH YjgK YiaL family protein
CH61_RS04315	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CH61_RS04325	COG0525	valine-tRNA ligase activity
CH61_RS04330	COG2927	DNA polymerase III (CHI subunit)
CH61_RS04340	COG0795	lipopolysaccharide-transporting ATPase activity
CH61_RS04345	COG0795	lipopolysaccharide-transporting ATPase activity
CH61_RS04355	COG0582	viral genome integration into host DNA
CH61_RS04415	COG1459	type II secretion system
CH61_RS04420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH61_RS04425	COG4969	Belongs to the N-Me-Phe pilin family
CH61_RS04435	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH61_RS04440	COG3725	Membrane protein required for beta-lactamase induction
CH61_RS04445	COG1113	amino acid transport
CH61_RS04450	COG2186	Transcriptional regulator
CH61_RS04455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CH61_RS04460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH61_RS04465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CH61_RS04480	COG1049	propionate catabolic process, 2-methylcitrate cycle
CH61_RS04490	COG0697	spore germination
CH61_RS04510	COG2132	Multicopper oxidase
CH61_RS04515	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CH61_RS04520	COG0288	reversible hydration of carbon dioxide
CH61_RS04525	COG1131	(ABC) transporter
CH61_RS04530	COG0842	Transport permease protein
CH61_RS04535	COG0726	polysaccharide deacetylase
CH61_RS04555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CH61_RS04560	COG0617	tRNA 3'-terminal CCA addition
CH61_RS04565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CH61_RS04580	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CH61_RS04585	COG1643	Atp-dependent helicase
CH61_RS04590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CH61_RS04595	COG1120	ATPase activity
CH61_RS04600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH61_RS04605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_RS04625	COG2860	membrane
CH61_RS04645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CH61_RS04650	COG3850	Histidine kinase
CH61_RS04650	COG3437	response regulator, receiver
CH61_RS04650	COG2205	protein histidine kinase activity
CH61_RS04650	COG4999	Histidine kinase
CH61_RS04655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH61_RS04665	COG3956	TIGRFAM MazG family protein
CH61_RS04685	COG0602	queuosine metabolic process
CH61_RS04690	COG0720	synthase
CH61_RS04740	COG0529	Catalyzes the synthesis of activated sulfate
CH61_RS04780	COG4942	peptidase
CH61_RS04780	COG1388	LysM domain
CH61_RS04785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CH61_RS04800	COG0698	ribose 5-phosphate isomerase
CH61_RS04805	COG1063	alcohol dehydrogenase
CH61_RS04810	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS04815	COG2376	Dihydroxyacetone kinase
CH61_RS04830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CH61_RS04850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS04855	COG1858	cytochrome C peroxidase
CH61_RS04865	COG4771	TonB-dependent receptor
CH61_RS04885	COG0024	Methionine aminopeptidase
CH61_RS04895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CH61_RS04895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CH61_RS04900	COG1070	Carbohydrate kinase
CH61_RS04905	COG3623	hexulose-6-phosphate isomerase
CH61_RS04910	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS04915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS04920	COG1129	ABC transporter
CH61_RS04935	COG1349	DNA-binding transcription factor activity
CH61_RS04940	COG0235	Class ii aldolase
CH61_RS04945	COG0243	molybdopterin cofactor binding
CH61_RS04950	COG0437	4 iron, 4 sulfur cluster binding
CH61_RS04955	COG3302	dmso reductase anchor subunit
CH61_RS04960	COG3381	protein complex oligomerization
CH61_RS04965	COG3038	cytochrome b561
CH61_RS04970	COG3783	Cytochrome b(562)
CH61_RS04980	COG1879	ABC-type sugar transport system periplasmic component
CH61_RS04990	COG1129	ABC transporter
CH61_RS04995	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS05000	COG3959	Transketolase, thiamine diphosphate binding domain
CH61_RS05005	COG3958	Transketolase
CH61_RS05010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH61_RS05050	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CH61_RS05075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_RS05080	COG1238	metal cluster binding
CH61_RS05085	COG2918	glutathione biosynthetic process
CH61_RS05115	COG4536	flavin adenine dinucleotide binding
CH61_RS05120	COG4137	Cytochrome C assembly protein
CH61_RS05125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CH61_RS05155	COG3137	Salt-induced outer membrane protein
CH61_RS05160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_RS05165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_RS05170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_RS05175	COG3279	Response regulator of the LytR AlgR family
CH61_RS05180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH61_RS05185	COG1605	Chorismate mutase
CH61_RS05185	COG0287	Prephenate dehydrogenase
CH61_RS05190	COG1605	Chorismate mutase
CH61_RS05190	COG0077	Prephenate dehydratase
CH61_RS05210	COG0077	Prephenate dehydratase
CH61_RS05210	COG1605	Chorismate mutase
CH61_RS05225	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CH61_RS05230	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH61_RS05235	COG0564	pseudouridine synthase activity
CH61_RS05245	COG0542	response to heat
CH61_RS05285	COG5544	Lipoprotein
CH61_RS05290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CH61_RS05295	COG1042	CoA-binding domain protein
CH61_RS05295	COG0045	succinate-CoA ligase (ADP-forming) activity
CH61_RS05295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH61_RS05300	COG3148	PFAM DTW domain containing protein
CH61_RS05305	COG3118	belongs to the thioredoxin family
CH61_RS05310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH61_RS05315	COG2814	Major facilitator Superfamily
CH61_RS05320	COG1566	PFAM secretion protein HlyD family protein
CH61_RS05325	COG1846	Transcriptional regulator
CH61_RS05335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CH61_RS05340	COG2814	Major facilitator Superfamily
CH61_RS05380	COG0765	amino acid transport
CH61_RS05390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH61_RS05410	COG2113	Glycine betaine
CH61_RS05415	COG4176	ABC-type proline glycine betaine transport system permease component
CH61_RS05420	COG4175	Glycine betaine
CH61_RS05425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CH61_RS05460	COG3328	transposase activity
CH61_RS05470	COG1278	Cold shock
CH61_RS05475	COG0747	negative chemotaxis
CH61_RS05485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_RS05490	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CH61_RS05495	COG1124	(ABC) transporter
CH61_RS05500	COG0831	urea catabolic process
CH61_RS05525	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CH61_RS05535	COG4413	Urea transporter
CH61_RS05540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CH61_RS05555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH61_RS05565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH61_RS05575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH61_RS05580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CH61_RS05585	COG1447	Phosphotransferase system cellobiose-specific component IIA
CH61_RS05590	COG1917	Cupin 2, conserved barrel domain protein
CH61_RS05590	COG2169	Transcriptional regulator
CH61_RS05610	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CH61_RS05615	COG0033	Phosphoglucomutase
CH61_RS05635	COG0745	RESPONSE REGULATOR receiver
CH61_RS05640	COG2205	protein histidine kinase activity
CH61_RS05675	COG3272	Protein of unknown function (DUF1722)
CH61_RS05685	COG5212	phosphodiesterase
CH61_RS05690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CH61_RS05700	COG1984	allophanate hydrolase subunit 2
CH61_RS05750	COG0513	Belongs to the DEAD box helicase family
CH61_RS05760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CH61_RS05775	COG3026	antisigma factor binding
CH61_RS05780	COG3086	response to oxidative stress
CH61_RS05870	COG2824	Alkylphosphonate utilization operon protein PhnA
CH61_RS05880	COG1704	LemA family
CH61_RS05900	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH61_RS05905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH61_RS05910	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CH61_RS05920	COG1138	Cytochrome C-type biogenesis protein
CH61_RS05925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CH61_RS05930	COG3088	subunit of a heme lyase
CH61_RS05930	COG4235	cytochrome complex assembly
CH61_RS05935	COG4235	cytochrome complex assembly
CH61_RS05935	COG3088	subunit of a heme lyase
CH61_RS05950	COG3691	Protein conserved in bacteria
CH61_RS05965	COG2062	phosphohistidine phosphatase, SixA
CH61_RS05975	COG2890	protein-(glutamine-N5) methyltransferase activity
CH61_RS05985	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CH61_RS05990	COG0730	response to heat
CH61_RS05995	COG3101	peptidyl-lysine hydroxylation
CH61_RS06010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_RS06015	COG1794	racemase activity, acting on amino acids and derivatives
CH61_RS06030	COG0697	spore germination
CH61_RS06055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CH61_RS06065	COG0586	Pfam SNARE associated Golgi protein
CH61_RS06075	COG0285	dihydrofolate synthase activity
CH61_RS06080	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CH61_RS06085	COG1286	toxin biosynthetic process
CH61_RS06090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CH61_RS06100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS06105	COG4215	(ABC) transporter
CH61_RS06110	COG4160	amino acid transport
CH61_RS06115	COG4598	ABC transporter
CH61_RS06120	COG1090	epimerase
CH61_RS06130	COG0622	Phosphoesterase
CH61_RS06135	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CH61_RS06140	COG3037	sugar-specific permease SgaT UlaA
CH61_RS06145	COG3328	transposase activity
CH61_RS06150	COG4953	penicillin-binding protein 1C
CH61_RS06155	COG3423	Transcriptional regulator
CH61_RS06205	COG2850	peptidyl-arginine hydroxylation
CH61_RS06210	COG3328	transposase activity
CH61_RS06225	COG1472	Belongs to the glycosyl hydrolase 3 family
CH61_RS06245	COG0656	L-ascorbic acid biosynthetic process
CH61_RS06250	COG0667	Aldo Keto reductase
CH61_RS06285	COG2453	phosphatase
CH61_RS06285	COG0671	phosphoesterase, PA-phosphatase related
CH61_RS06290	COG2267	carboxylic ester hydrolase activity
CH61_RS06300	COG4589	Belongs to the CDS family
CH61_RS06305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CH61_RS06355	COG2501	S4 domain
CH61_RS06375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CH61_RS06380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH61_RS06400	COG0581	inorganic phosphate transmembrane transporter activity
CH61_RS06410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CH61_RS06425	COG2239	Acts as a magnesium transporter
CH61_RS06430	COG0443	Heat shock 70 kDa protein
CH61_RS06435	COG1177	transmembrane transport
CH61_RS06440	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH61_RS06450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CH61_RS06460	COG3842	ATPase activity
CH61_RS06485	COG2205	protein histidine kinase activity
CH61_RS06490	COG2205	protein histidine kinase activity
CH61_RS06495	COG0745	RESPONSE REGULATOR receiver
CH61_RS06500	COG3422	double-strand break repair
CH61_RS06505	COG0826	peptidase U32
CH61_RS06525	COG0351	phosphomethylpyrimidine kinase
CH61_RS06540	COG3328	transposase activity
CH61_RS06590	COG0517	IMP dehydrogenase activity
CH61_RS06590	COG0516	GMP reductase activity
CH61_RS06600	COG1645	bacterial-type flagellum-dependent swarming motility
CH61_RS06615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH61_RS06620	COG2976	Protein conserved in bacteria
CH61_RS06665	COG3468	outer membrane autotransporter barrel domain protein
CH61_RS06670	COG3468	outer membrane autotransporter barrel domain protein
CH61_RS06690	COG2975	iron-sulfur cluster assembly
CH61_RS06695	COG0633	Ferredoxin
CH61_RS06700	COG0443	Heat shock 70 kDa protein
CH61_RS06715	COG0822	iron-sulfur transferase activity
CH61_RS06720	COG1104	cysteine desulfurase activity
CH61_RS06745	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CH61_RS06750	COG3683	transport system, periplasmic component
CH61_RS06755	COG3711	transcriptional antiterminator
CH61_RS06760	COG2814	Major facilitator Superfamily
CH61_RS06780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_RS06780	COG1017	nitric oxide dioxygenase activity
CH61_RS06785	COG2188	Transcriptional regulator
CH61_RS06790	COG2188	Transcriptional regulator
CH61_RS06795	COG0347	Belongs to the P(II) protein family
CH61_RS06800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CH61_RS06800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH61_RS06805	COG2204	response regulator
CH61_RS06810	COG3170	Tfp pilus assembly protein FimV
CH61_RS06815	COG2205	protein histidine kinase activity
CH61_RS06855	COG0560	Phosphoserine phosphatase
CH61_RS06865	COG1737	Transcriptional regulator
CH61_RS06870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_RS06890	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CH61_RS06940	COG3188	usher protein
CH61_RS06945	COG3328	transposase activity
CH61_RS06950	COG3188	usher protein
CH61_RS06955	COG3121	Chaperone
CH61_RS07015	COG2951	lytic endotransglycosylase activity
CH61_RS07050	COG0243	molybdopterin cofactor binding
CH61_RS07055	COG0437	4 iron, 4 sulfur cluster binding
CH61_RS07060	COG3302	dmso reductase anchor subunit
CH61_RS07065	COG3381	protein complex oligomerization
CH61_RS07095	COG3038	cytochrome b561
CH61_RS07100	COG0436	Aminotransferase
CH61_RS07125	COG0667	Aldo Keto reductase
CH61_RS07140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH61_RS07195	COG3530	Putative quorum-sensing-regulated virulence factor
CH61_RS07210	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CH61_RS07220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS07245	COG2205	protein histidine kinase activity
CH61_RS07250	COG0745	RESPONSE REGULATOR receiver
CH61_RS07255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_RS07270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CH61_RS07290	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CH61_RS07300	COG5002	protein histidine kinase activity
CH61_RS07300	COG3850	Histidine kinase
CH61_RS07305	COG0745	RESPONSE REGULATOR receiver
CH61_RS07320	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CH61_RS07325	COG4208	sulfate ABC transporter
CH61_RS07330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CH61_RS07335	COG4150	thiosulfate binding
CH61_RS07345	COG1737	Transcriptional regulator
CH61_RS07355	COG2731	YhcH YjgK YiaL family protein
CH61_RS07365	COG4886	Leucine-rich repeat (LRR) protein
CH61_RS07375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CH61_RS07380	COG2837	iron assimilation
CH61_RS07390	COG3111	PFAM Bacterial OB fold (BOF) protein
CH61_RS07435	COG3005	denitrification pathway
CH61_RS07440	COG3043	anaerobic respiration
CH61_RS07450	COG3062	negative regulation of establishment of protein localization
CH61_RS07455	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_RS07455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_RS07460	COG2197	response regulator
CH61_RS07470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_RS07480	COG1988	membrane-bound metal-dependent
CH61_RS07485	COG0641	radical SAM
CH61_RS07490	COG3119	arylsulfatase activity
CH61_RS07495	COG3842	ATPase activity
CH61_RS07500	COG1175	transmembrane transport
CH61_RS07515	COG1393	Belongs to the ArsC family
CH61_RS07525	COG1876	peptidase activity
CH61_RS07545	COG2321	neutral zinc metallopeptidase
CH61_RS07565	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CH61_RS07575	COG2716	regulation of RNA biosynthetic process
CH61_RS07580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CH61_RS07600	COG0628	permease
CH61_RS07605	COG4783	chaperone-mediated protein folding
CH61_RS07610	COG1393	Belongs to the ArsC family
CH61_RS07635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CH61_RS07645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CH61_RS07650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CH61_RS07655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CH61_RS07660	COG4181	ATPase activity
CH61_RS07665	COG2755	lipolytic protein G-D-S-L family
CH61_RS07670	COG0300	oxidoreductase activity
CH61_RS07675	COG3118	belongs to the thioredoxin family
CH61_RS07680	COG0330	HflC and HflK could
CH61_RS07685	COG1585	Membrane protein implicated in regulation of membrane protease activity
CH61_RS07690	COG0789	Transcriptional regulator
CH61_RS07695	COG2217	Heavy metal translocating P-type atpase
CH61_RS07700	COG3735	TraB family
CH61_RS07705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CH61_RS07720	COG0737	Belongs to the 5'-nucleotidase family
CH61_RS07725	COG0737	Belongs to the 5'-nucleotidase family
CH61_RS07730	COG0737	Belongs to the 5'-nucleotidase family
CH61_RS07735	COG2223	nitrite transmembrane transporter activity
CH61_RS07740	COG4651	solute:proton antiporter activity
CH61_RS07740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CH61_RS07745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_RS07750	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CH61_RS07810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_RS07835	COG0543	2 iron, 2 sulfur cluster binding
CH61_RS07835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_RS07865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CH61_RS07895	COG2832	Protein of unknown function (DUF454)
CH61_RS07910	COG3264	Mechanosensitive ion channel
CH61_RS07910	COG1196	nuclear chromosome segregation
CH61_RS07915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CH61_RS07920	COG1309	transcriptional regulator
CH61_RS07925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_RS07930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_RS07940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH61_RS07960	COG3695	enzyme binding
CH61_RS07965	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CH61_RS07970	COG1946	Acyl-CoA thioesterase
CH61_RS07975	COG0004	ammonium transporteR
CH61_RS07980	COG0347	Belongs to the P(II) protein family
CH61_RS07985	COG1132	(ABC) transporter
CH61_RS07990	COG1132	(ABC) transporter
CH61_RS07995	COG1522	sequence-specific DNA binding
CH61_RS08010	COG4533	DNA binding
CH61_RS08020	COG0824	Thioesterase
CH61_RS08025	COG1555	photosystem II stabilization
CH61_RS08030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CH61_RS08035	COG0776	regulation of translation
CH61_RS08040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CH61_RS08065	COG0271	Belongs to the BolA IbaG family
CH61_RS08070	COG3056	Lipoprotein
CH61_RS08075	COG2223	nitrite transmembrane transporter activity
CH61_RS08085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CH61_RS08090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CH61_RS08095	COG1845	cytochrome c oxidase, subunit III
CH61_RS08100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CH61_RS08110	COG2814	Major facilitator Superfamily
CH61_RS08120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CH61_RS08125	COG0693	protein deglycase activity
CH61_RS08145	COG0142	geranyltranstransferase activity
CH61_RS08165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CH61_RS08170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CH61_RS08185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH61_RS08185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CH61_RS08210	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH61_RS08215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CH61_RS08220	COG1862	Preprotein translocase
CH61_RS08240	COG0450	alkyl hydroperoxide reductase
CH61_RS08270	COG0366	Alpha amylase catalytic
CH61_RS08290	COG5002	protein histidine kinase activity
CH61_RS08295	COG0745	RESPONSE REGULATOR receiver
CH61_RS08305	COG0420	3'-5' exonuclease activity
CH61_RS08310	COG0419	ATPase involved in DNA repair
CH61_RS08325	COG1940	carbohydrate kinase activity
CH61_RS08360	COG2226	methyltransferase
CH61_RS08420	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH61_RS08440	COG1477	protein flavinylation
CH61_RS08460	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH61_RS08465	COG1805	sodium ion transport
CH61_RS08475	COG3034	peptidoglycan biosynthetic process
CH61_RS08480	COG0121	glutamine amidotransferase
CH61_RS08490	COG1960	acyl-CoA dehydrogenase activity
CH61_RS08500	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
CH61_RS08520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CH61_RS08540	COG0582	viral genome integration into host DNA
CH61_RS08545	COG2963	transposase activity
CH61_RS08550	COG0582	viral genome integration into host DNA
CH61_RS08560	COG0596	Alpha beta hydrolase
CH61_RS08580	COG0735	belongs to the Fur family
CH61_RS08605	COG1263	PTS System
CH61_RS08605	COG2190	(PTS) system
CH61_RS08605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_RS08615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CH61_RS08620	COG1846	Transcriptional regulator
CH61_RS08620	COG1940	carbohydrate kinase activity
CH61_RS08625	COG0647	UMP catabolic process
CH61_RS08630	COG0367	asparagine synthase
CH61_RS08665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH61_RS08670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CH61_RS08675	COG1702	phosphate starvation-inducible protein PhoH
CH61_RS08685	COG4535	Mg2 and Co2 transporter CorC
CH61_RS08690	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CH61_RS08700	COG0765	amino acid transport
CH61_RS08705	COG0765	amino acid transport
CH61_RS08710	COG1126	abc transporter atp-binding protein
CH61_RS08715	COG2888	peptidyl-tyrosine sulfation
CH61_RS08730	COG1466	dna polymerase III delta subunit
CH61_RS08740	COG0799	negative regulation of ribosome biogenesis
CH61_RS08750	COG0768	penicillin binding
CH61_RS08755	COG0772	Belongs to the SEDS family
CH61_RS08760	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH61_RS08765	COG1686	Belongs to the peptidase S11 family
CH61_RS08785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CH61_RS08795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CH61_RS08810	COG2197	response regulator
CH61_RS08835	COG5265	(ABC) transporter
CH61_RS08845	COG3718	enzyme involved in inositol metabolism
CH61_RS08855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_RS08860	COG0673	inositol 2-dehydrogenase activity
CH61_RS08865	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS08870	COG1129	ABC transporter
CH61_RS08885	COG3962	Belongs to the TPP enzyme family
CH61_RS08905	COG2373	Large extracellular alpha-helical protein
CH61_RS08910	COG4953	penicillin-binding protein 1C
CH61_RS08915	COG3328	transposase activity
CH61_RS08930	COG1609	Transcriptional regulator
CH61_RS08935	COG0857	belongs to the CobB CobQ family
CH61_RS08935	COG0280	phosphate acetyltransferase
CH61_RS08960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_RS08965	COG0490	domain, Protein
CH61_RS08965	COG0471	metal ion transport
CH61_RS08980	COG0436	Aminotransferase
CH61_RS08990	COG0583	DNA-binding transcription factor activity
CH61_RS09000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH61_RS09020	COG1034	ATP synthesis coupled electron transport
CH61_RS09035	COG0839	Belongs to the complex I subunit 6 family
CH61_RS09045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CH61_RS09050	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH61_RS09065	COG2731	YhcH YjgK YiaL family protein
CH61_RS09070	COG3265	gluconokinase activity
CH61_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS09080	COG1649	PFAM Uncharacterised BCR, COG1649
CH61_RS09085	COG1609	Transcriptional regulator
CH61_RS09095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH61_RS09110	COG0129	dihydroxy-acid dehydratase activity
CH61_RS09125	COG4575	ribosome binding
CH61_RS09135	COG1169	isochorismate synthase
CH61_RS09150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CH61_RS09165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CH61_RS09195	COG1126	abc transporter atp-binding protein
CH61_RS09200	COG0765	amino acid transport
CH61_RS09205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS09235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CH61_RS09255	COG1063	alcohol dehydrogenase
CH61_RS09260	COG1879	ABC-type sugar transport system periplasmic component
CH61_RS09265	COG1129	ABC transporter
CH61_RS09270	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS09275	COG1609	Transcriptional regulator
CH61_RS09280	COG0583	DNA-binding transcription factor activity
CH61_RS09285	COG0473	3-isopropylmalate dehydrogenase activity
CH61_RS09295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH61_RS09300	COG4638	Rieske (2fe-2S)
CH61_RS09305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_RS09310	COG2831	hemolysin activation secretion protein
CH61_RS09315	COG3210	domain, Protein
CH61_RS09335	COG3210	domain, Protein
CH61_RS09355	COG3210	domain, Protein
CH61_RS09365	COG3842	ATPase activity
CH61_RS09375	COG1609	Transcriptional regulator
CH61_RS09390	COG0395	ABC-type sugar transport system, permease component
CH61_RS09395	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CH61_RS09415	COG0668	transmembrane transport
CH61_RS09420	COG1518	maintenance of DNA repeat elements
CH61_RS09425	COG1203	CRISPR-associated helicase, Cas3
CH61_RS09455	COG0667	Aldo Keto reductase
CH61_RS09465	COG0477	Major facilitator Superfamily
CH61_RS09475	COG0583	DNA-binding transcription factor activity
CH61_RS09480	COG2771	luxR family
CH61_RS09485	COG3916	Acyl-homoserine-lactone synthase
CH61_RS09515	COG0628	permease
CH61_RS09530	COG3328	transposase activity
CH61_RS09535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_RS09545	COG3001	Fructosamine kinase
CH61_RS09555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH61_RS09560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH61_RS09565	COG1121	(ABC) transporter
CH61_RS09570	COG0803	Belongs to the bacterial solute-binding protein 9 family
CH61_RS09595	COG4249	Peptidase C14 caspase catalytic subunit p20
CH61_RS09625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CH61_RS09625	COG0072	phenylalanine-tRNA ligase activity
CH61_RS09630	COG0776	regulation of translation
CH61_RS09645	COG0386	Belongs to the glutathione peroxidase family
CH61_RS09690	COG0791	NLP P60 protein
CH61_RS09715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH61_RS09715	COG0574	Belongs to the PEP-utilizing enzyme family
CH61_RS09720	COG0628	permease
CH61_RS09725	COG0247	lactate metabolic process
CH61_RS09725	COG0277	FAD linked oxidase domain protein
CH61_RS09730	COG2050	protein possibly involved in aromatic compounds catabolism
CH61_RS09740	COG0316	Belongs to the HesB IscA family
CH61_RS09745	COG0719	Fe-S assembly protein
CH61_RS09750	COG0396	ATPase activity
CH61_RS09755	COG0719	Fe-S assembly protein
CH61_RS09770	COG1376	ErfK ybiS ycfS ynhG family protein
CH61_RS09770	COG1388	LysM domain
CH61_RS09820	COG0307	riboflavin synthase, alpha
CH61_RS09825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CH61_RS09830	COG2814	Major facilitator Superfamily
CH61_RS09835	COG0583	DNA-binding transcription factor activity
CH61_RS09850	COG0791	NLP P60 protein
CH61_RS09860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CH61_RS09865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CH61_RS09870	COG0346	lactoylglutathione lyase activity
CH61_RS09880	COG1902	pentaerythritol trinitrate reductase activity
CH61_RS09885	COG1309	transcriptional regulator
CH61_RS09890	COG2194	sulfuric ester hydrolase activity
CH61_RS09895	COG3313	Fe-S protein
CH61_RS09900	COG4989	oxidoreductase activity
CH61_RS09910	COG3133	Outer membrane lipoprotein
CH61_RS09920	COG3895	Periplasmic Protein
CH61_RS09940	COG0625	glutathione transferase activity
CH61_RS09965	COG3104	oligopeptide transport
CH61_RS09970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH61_RS09970	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CH61_RS09975	COG4172	Belongs to the ABC transporter superfamily
CH61_RS09985	COG4171	peptide transport system, permease
CH61_RS09990	COG4168	peptide transport system, permease
CH61_RS09995	COG4166	transmembrane transport
CH61_RS10015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CH61_RS10020	COG1842	Phage shock protein A
CH61_RS10030	COG1983	PspC domain protein
CH61_RS10040	COG3106	COG3106 Predicted ATPase
CH61_RS10050	COG5654	RES domain protein
CH61_RS10055	COG5642	Protein of unknown function (DUF2384)
CH61_RS10070	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CH61_RS10075	COG4948	Mandelate Racemase Muconate Lactonizing
CH61_RS10080	COG2866	Carboxypeptidase
CH61_RS10085	COG4166	transmembrane transport
CH61_RS10105	COG0657	acetylesterase activity
CH61_RS10115	COG0674	pyruvate-flavodoxin oxidoreductase activity
CH61_RS10115	COG1013	pyruvate-flavodoxin oxidoreductase activity
CH61_RS10115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CH61_RS10115	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CH61_RS10125	COG1285	pathogenesis
CH61_RS10130	COG3042	response to heat
CH61_RS10135	COG3187	Heat shock protein
CH61_RS10140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CH61_RS10145	COG2911	Protein conserved in bacteria
CH61_RS10155	COG3784	Protein of unknown function (DUF1318)
CH61_RS10160	COG0246	Mannitol dehydrogenase
CH61_RS10165	COG2390	Transcriptional regulator
CH61_RS10175	COG1643	Atp-dependent helicase
CH61_RS10190	COG3591	Belongs to the peptidase S1B family
CH61_RS10205	COG3038	cytochrome b561
CH61_RS10240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CH61_RS10245	COG2205	protein histidine kinase activity
CH61_RS10250	COG0745	RESPONSE REGULATOR receiver
CH61_RS10260	COG0531	amino acid
CH61_RS10275	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CH61_RS10280	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CH61_RS10285	COG0589	response to stress
CH61_RS10290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CH61_RS10295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH61_RS10315	COG1011	Hydrolase
CH61_RS10320	COG0440	acetolactate synthase activity
CH61_RS10325	COG0028	Belongs to the TPP enzyme family
CH61_RS10350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CH61_RS10355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH61_RS10375	COG1609	Transcriptional regulator
CH61_RS10395	COG4128	Pfam Zonular occludens toxin
CH61_RS10445	COG0038	chloride channel
CH61_RS10450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CH61_RS10455	COG1940	carbohydrate kinase activity
CH61_RS10475	COG0114	fumarate hydratase activity
CH61_RS10485	COG5339	Protein conserved in bacteria
CH61_RS10495	COG0385	Bile acid
CH61_RS10500	COG0673	inositol 2-dehydrogenase activity
CH61_RS10510	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS10515	COG1129	ABC transporter
CH61_RS10520	COG1879	ABC-type sugar transport system periplasmic component
CH61_RS10535	COG2274	protein secretion by the type I secretion system
CH61_RS10540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_RS10550	COG1132	(ABC) transporter
CH61_RS10580	COG3708	Transcriptional regulator
CH61_RS10580	COG2207	Transcriptional regulator
CH61_RS10585	COG4658	electron transport chain
CH61_RS10590	COG4659	FMN binding
CH61_RS10600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CH61_RS10605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_RS10610	COG2271	Major facilitator Superfamily
CH61_RS10620	COG1966	Carbon starvation protein
CH61_RS10625	COG2879	small protein
CH61_RS10630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CH61_RS10650	COG0023	Translation Initiation Factor
CH61_RS10665	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CH61_RS10670	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CH61_RS10675	COG0671	phosphoesterase, PA-phosphatase related
CH61_RS10685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CH61_RS10695	COG0583	DNA-binding transcription factor activity
CH61_RS10715	COG0616	signal peptide processing
CH61_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS10730	COG1187	pseudouridine synthase activity
CH61_RS10735	COG0009	L-threonylcarbamoyladenylate synthase
CH61_RS10760	COG0512	Glutamine amidotransferase of anthranilate synthase
CH61_RS10770	COG0134	indole-3-glycerol-phosphate synthase activity
CH61_RS10770	COG0135	phosphoribosylanthranilate isomerase activity
CH61_RS10790	COG3047	cAMP biosynthetic process
CH61_RS10825	COG3328	transposase activity
CH61_RS10830	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CH61_RS10835	COG2350	Protein conserved in bacteria
CH61_RS10875	COG4608	Belongs to the ABC transporter superfamily
CH61_RS10880	COG0444	Belongs to the ABC transporter superfamily
CH61_RS10885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CH61_RS10890	COG0601	transmembrane transport
CH61_RS10900	COG2095	MarC family integral membrane protein
CH61_RS10905	COG1454	alcohol dehydrogenase
CH61_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
CH61_RS10935	COG0745	RESPONSE REGULATOR receiver
CH61_RS10945	COG0788	formyltetrahydrofolate deformylase activity
CH61_RS10960	COG0583	DNA-binding transcription factor activity
CH61_RS10965	COG0708	Exodeoxyribonuclease III
CH61_RS10970	COG0494	nUDIX hydrolase
CH61_RS10980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CH61_RS10985	COG0709	Synthesizes selenophosphate from selenide and ATP
CH61_RS10990	COG0778	Nitroreductase
CH61_RS10995	COG0616	signal peptide processing
CH61_RS11000	COG0252	asparaginase activity
CH61_RS11005	COG1335	isochorismatase
CH61_RS11010	COG3139	Protein of unknown function (DUF1315)
CH61_RS11030	COG3713	MltA-interacting MipA family protein
CH61_RS11035	COG2766	serine protein kinase
CH61_RS11050	COG0583	DNA-binding transcription factor activity
CH61_RS11060	COG2814	Major facilitator Superfamily
CH61_RS11070	COG2719	SpoVR family
CH61_RS11100	COG1104	cysteine desulfurase activity
CH61_RS11110	COG3328	transposase activity
CH61_RS11285	COG3328	transposase activity
CH61_RS11390	COG0582	viral genome integration into host DNA
CH61_RS11400	COG0179	Fumarylacetoacetate (FAA) hydrolase
CH61_RS11405	COG2951	lytic endotransglycosylase activity
CH61_RS11420	COG2894	cell division
CH61_RS11425	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CH61_RS11430	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CH61_RS11435	COG0318	PFAM AMP-dependent synthetase and ligase
CH61_RS11440	COG3065	identical protein binding
CH61_RS11450	COG1199	ATP-dependent helicase activity
CH61_RS11455	COG0251	oxidation-reduction process
CH61_RS11470	COG0800	Aldolase
CH61_RS11480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CH61_RS11485	COG1737	Transcriptional regulator
CH61_RS11490	COG0469	pyruvate kinase activity
CH61_RS11495	COG1560	Kdo2-lipid A biosynthetic process
CH61_RS11500	COG0739	heme binding
CH61_RS11505	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CH61_RS11515	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CH61_RS11540	COG0494	nUDIX hydrolase
CH61_RS11550	COG1801	Protein of unknown function DUF72
CH61_RS11555	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CH61_RS11575	COG3102	Protein conserved in bacteria
CH61_RS11595	COG0728	peptidoglycan biosynthetic process
CH61_RS11600	COG0673	inositol 2-dehydrogenase activity
CH61_RS11605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CH61_RS11620	COG3381	protein complex oligomerization
CH61_RS11635	COG1940	carbohydrate kinase activity
CH61_RS11640	COG0584	glycerophosphoryl diester phosphodiesterase
CH61_RS11645	COG3842	ATPase activity
CH61_RS11660	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH61_RS11665	COG3833	ABC-type maltose transport systems, permease component
CH61_RS11690	COG0659	secondary active sulfate transmembrane transporter activity
CH61_RS11705	COG0659	secondary active sulfate transmembrane transporter activity
CH61_RS11730	COG2890	protein-(glutamine-N5) methyltransferase activity
CH61_RS11760	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CH61_RS11780	COG0012	GTP binding
CH61_RS11835	COG5002	protein histidine kinase activity
CH61_RS11875	COG0500	methyltransferase
CH61_RS11900	COG3328	transposase activity
CH61_RS11945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_RS11950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH61_RS11955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CH61_RS11970	COG0402	S-adenosylhomocysteine deaminase activity
CH61_RS12040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH61_RS12045	COG3850	Histidine kinase
CH61_RS12050	COG0387	Pfam Sodium calcium exchanger
CH61_RS12055	COG1702	phosphate starvation-inducible protein PhoH
CH61_RS12070	COG3658	cytochrome
CH61_RS12075	COG1215	transferase activity, transferring glycosyl groups
CH61_RS12080	COG1649	PFAM Uncharacterised BCR, COG1649
CH61_RS12080	COG0726	polysaccharide deacetylase
CH61_RS12085	COG0457	Tetratricopeptide repeat
CH61_RS12090	COG0006	proline dipeptidase activity
CH61_RS12110	COG1136	(ABC) transporter
CH61_RS12110	COG0577	efflux transmembrane transporter activity
CH61_RS12120	COG1136	(ABC) transporter
CH61_RS12120	COG0577	efflux transmembrane transporter activity
CH61_RS12135	COG0672	)-iron permease
CH61_RS12145	COG2066	Belongs to the glutaminase family
CH61_RS12155	COG1349	DNA-binding transcription factor activity
CH61_RS12165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CH61_RS12170	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CH61_RS12185	COG2814	Major facilitator Superfamily
CH61_RS12210	COG2030	dehydratase
CH61_RS12215	COG0427	acetyl-CoA hydrolase
CH61_RS12230	COG2205	protein histidine kinase activity
CH61_RS12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS12245	COG3188	usher protein
CH61_RS12255	COG3121	Chaperone
CH61_RS12265	COG0582	viral genome integration into host DNA
CH61_RS12270	COG1169	isochorismate synthase
CH61_RS12275	COG2814	Major facilitator Superfamily
CH61_RS12280	COG1132	(ABC) transporter
CH61_RS12315	COG1021	2,3-dihydroxybenzoate-AMP ligase
CH61_RS12320	COG4771	TonB-dependent receptor
CH61_RS12395	COG3842	ATPase activity
CH61_RS12400	COG0395	ABC-type sugar transport system, permease component
CH61_RS12405	COG1175	transmembrane transport
CH61_RS12415	COG0673	inositol 2-dehydrogenase activity
CH61_RS12425	COG2188	Transcriptional regulator
CH61_RS12565	COG2197	response regulator
CH61_RS12575	COG3136	membrane protein required for alginate biosynthesis
CH61_RS12595	COG1113	amino acid transport
CH61_RS12615	COG2822	iron ion transport
CH61_RS12620	COG0672	)-iron permease
CH61_RS12635	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH61_RS12635	COG0506	proline dehydrogenase activity
CH61_RS12635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CH61_RS12650	COG1126	abc transporter atp-binding protein
CH61_RS12655	COG0765	amino acid transport
CH61_RS12660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS12675	COG1191	sigma factor activity
CH61_RS12710	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CH61_RS12715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CH61_RS12720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CH61_RS12735	COG1677	Flagellar hook-basal body complex protein FliE
CH61_RS12755	COG1157	protein secretion by the type III secretion system
CH61_RS12770	COG1580	Controls the rotational direction of flagella during chemotaxis
CH61_RS12795	COG1987	bacterial-type flagellum assembly
CH61_RS12815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_RS12820	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS12825	COG1129	ABC transporter
CH61_RS12835	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS12840	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS12840	COG3347	Dehydrogenase
CH61_RS12845	COG2390	Transcriptional regulator
CH61_RS12855	COG1256	bacterial-type flagellum assembly
CH61_RS12895	COG1558	bacterial-type flagellum-dependent cell motility
CH61_RS12900	COG1815	bacterial-type flagellum-dependent cell motility
CH61_RS12910	COG2747	anti-sigma28 factor FlgM
CH61_RS12915	COG3418	PFAM FlgN family protein
CH61_RS12940	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH61_RS12945	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH61_RS12975	COG2372	response to copper ion
CH61_RS12980	COG1528	Iron-storage protein
CH61_RS12995	COG1770	oligopeptidase
CH61_RS13010	COG3141	response to X-ray
CH61_RS13015	COG0513	Belongs to the DEAD box helicase family
CH61_RS13040	COG1760	l-serine dehydratase
CH61_RS13045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CH61_RS13050	COG2368	4-hydroxyphenylacetate
CH61_RS13065	COG3971	2-oxopent-4-enoate hydratase activity
CH61_RS13075	COG3384	dioxygenase
CH61_RS13080	COG1012	belongs to the aldehyde dehydrogenase family
CH61_RS13095	COG1846	Transcriptional regulator
CH61_RS13100	COG1253	flavin adenine dinucleotide binding
CH61_RS13105	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS13105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_RS13110	COG3715	PTS system
CH61_RS13115	COG3716	PTS system mannose fructose sorbose family IID component
CH61_RS13135	COG5002	protein histidine kinase activity
CH61_RS13135	COG5001	Diguanylate cyclase
CH61_RS13135	COG3447	MASE1 domain protein
CH61_RS13145	COG2226	methyltransferase
CH61_RS13150	COG1496	oxidoreductase activity
CH61_RS13175	COG1113	amino acid transport
CH61_RS13210	COG2207	Transcriptional regulator
CH61_RS13220	COG1132	(ABC) transporter
CH61_RS13270	COG3328	transposase activity
CH61_RS13275	COG1917	Cupin 2, conserved barrel domain protein
CH61_RS13285	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS13295	COG1175	transmembrane transport
CH61_RS13300	COG0395	ABC-type sugar transport system, permease component
CH61_RS13305	COG3842	ATPase activity
CH61_RS13310	COG1653	transport
CH61_RS13315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CH61_RS13320	COG1988	membrane-bound metal-dependent
CH61_RS13325	COG1823	symporter activity
CH61_RS13330	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH61_RS13340	COG0823	Involved in the tonB-independent uptake of proteins
CH61_RS13345	COG2814	Major facilitator Superfamily
CH61_RS13350	COG3121	Chaperone
CH61_RS13365	COG3121	Chaperone
CH61_RS13370	COG3539	Fimbrial protein
CH61_RS13380	COG0793	Belongs to the peptidase S41A family
CH61_RS13390	COG1956	GAF domain-containing protein
CH61_RS13395	COG2995	paraquat-inducible protein a
CH61_RS13400	COG3008	intermembrane lipid transfer
CH61_RS13420	COG3121	Chaperone
CH61_RS13475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CH61_RS13485	COG5295	Hep Hag repeat protein
CH61_RS13495	COG3023	N-Acetylmuramoyl-L-alanine amidase
CH61_RS13505	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CH61_RS13510	COG0745	RESPONSE REGULATOR receiver
CH61_RS13520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CH61_RS13525	COG0840	transmembrane signaling receptor activity
CH61_RS13530	COG0840	transmembrane signaling receptor activity
CH61_RS13535	COG0840	transmembrane signaling receptor activity
CH61_RS13555	COG2964	Protein conserved in bacteria
CH61_RS13565	COG0251	oxidation-reduction process
CH61_RS13570	COG2271	Major facilitator Superfamily
CH61_RS13575	COG0835	chemotaxis
CH61_RS13580	COG2198	Histidine kinase
CH61_RS13580	COG0643	Histidine kinase
CH61_RS13585	COG1360	Flagellar Motor Protein
CH61_RS13610	COG1285	pathogenesis
CH61_RS13640	COG0604	alcohol dehydrogenase
CH61_RS13640	COG3321	synthase
CH61_RS13640	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS13650	COG1522	sequence-specific DNA binding
CH61_RS13675	COG1733	regulation of RNA biosynthetic process
CH61_RS13680	COG0702	epimerase
CH61_RS13685	COG0840	transmembrane signaling receptor activity
CH61_RS13700	COG0538	isocitrate dehydrogenase activity
CH61_RS13705	COG1187	pseudouridine synthase activity
CH61_RS13725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CH61_RS13735	COG0745	RESPONSE REGULATOR receiver
CH61_RS13745	COG2850	peptidyl-arginine hydroxylation
CH61_RS13760	COG1940	carbohydrate kinase activity
CH61_RS13765	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH61_RS13775	COG4591	ABC-type transport system involved in lipoprotein release permease component
CH61_RS13780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CH61_RS13785	COG3134	Outer membrane lipoprotein
CH61_RS13800	COG3328	transposase activity
CH61_RS13815	COG1252	NADH dehydrogenase
CH61_RS13825	COG1472	Belongs to the glycosyl hydrolase 3 family
CH61_RS13840	COG5633	Lipoprotein
CH61_RS13845	COG0537	adenosine 5'-monophosphoramidase activity
CH61_RS13850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CH61_RS13860	COG1263	PTS System
CH61_RS13860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_RS13865	COG0084	hydrolase, TatD family'
CH61_RS13870	COG0470	DNA polymerase III
CH61_RS13880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CH61_RS13885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CH61_RS13895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_RS13925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CH61_RS13930	COG1399	metal-binding, possibly nucleic acid-binding protein
CH61_RS13935	COG0424	maF-like protein
CH61_RS13950	COG0564	pseudouridine synthase activity
CH61_RS13955	COG1530	ribonuclease E activity
CH61_RS13960	COG3328	transposase activity
CH61_RS13965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CH61_RS13995	COG2223	nitrite transmembrane transporter activity
CH61_RS14015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CH61_RS14040	COG3122	Protein conserved in bacteria
CH61_RS14060	COG0534	Mate efflux family protein
CH61_RS14075	COG4948	Mandelate Racemase Muconate Lactonizing
CH61_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS14090	COG3011	Protein conserved in bacteria
CH61_RS14095	COG2271	Major facilitator Superfamily
CH61_RS14100	COG1388	LysM domain
CH61_RS14100	COG1470	cell adhesion involved in biofilm formation
CH61_RS14105	COG3328	transposase activity
CH61_RS14120	COG2925	Exonuclease
CH61_RS14125	COG0531	amino acid
CH61_RS14135	COG0371	Dehydrogenase
CH61_RS14140	COG1129	ABC transporter
CH61_RS14145	COG1129	ABC transporter
CH61_RS14150	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS14160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_RS14170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CH61_RS14180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH61_RS14180	COG0131	Imidazoleglycerol-phosphate dehydratase
CH61_RS14200	COG0140	phosphoribosyl-ATP diphosphatase activity
CH61_RS14200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CH61_RS14210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH61_RS14215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CH61_RS14230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CH61_RS14235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_RS14240	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_RS14245	COG1120	ATPase activity
CH61_RS14260	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CH61_RS14265	COG0076	glutamate decarboxylase activity
CH61_RS14270	COG4114	ferric iron reductase
CH61_RS14275	COG1253	flavin adenine dinucleotide binding
CH61_RS14280	COG2982	Protein involved in outer membrane biogenesis
CH61_RS14295	COG0489	protein tyrosine kinase activity
CH61_RS14340	COG2814	Major facilitator Superfamily
CH61_RS14350	COG1346	cytolysis
CH61_RS14365	COG2949	membrane
CH61_RS14370	COG4211	Belongs to the binding-protein-dependent transport system permease family
CH61_RS14385	COG2311	Membrane
CH61_RS14395	COG0477	Major facilitator Superfamily
CH61_RS14400	COG0583	DNA-binding transcription factor activity
CH61_RS14435	COG1136	(ABC) transporter
CH61_RS14445	COG0303	'Molybdopterin
CH61_RS14455	COG3328	transposase activity
CH61_RS14465	COG0488	(ABC) transporter
CH61_RS14600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CH61_RS14605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CH61_RS14615	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS14620	COG1024	Enoyl-CoA hydratase
CH61_RS14630	COG3425	synthase
CH61_RS14635	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS14640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_RS14645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CH61_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS14690	COG2920	part of a sulfur-relay system
CH61_RS14710	COG1832	CoA-binding protein
CH61_RS14725	COG0210	DNA helicase
CH61_RS14730	COG3304	Inner membrane component domain
CH61_RS14735	COG1289	transmembrane transporter activity
CH61_RS14740	COG3070	regulator of competence-specific genes
CH61_RS14770	COG1067	ATP-dependent peptidase activity
CH61_RS14785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_RS14805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CH61_RS14820	COG3130	regulation of translation
CH61_RS14830	COG3009	Protein conserved in bacteria
CH61_RS14835	COG3008	intermembrane lipid transfer
CH61_RS14835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CH61_RS14840	COG2995	paraquat-inducible protein a
CH61_RS14845	COG0488	(ABC) transporter
CH61_RS14855	COG3217	Mosc domain protein beta barrel domain protein
CH61_RS14855	COG0633	Ferredoxin
CH61_RS14870	COG0308	aminopeptidase N
CH61_RS14895	COG1448	Aminotransferase
CH61_RS14900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH61_RS14905	COG3108	Peptidase M15
CH61_RS14910	COG2989	Protein conserved in bacteria
CH61_RS14940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CH61_RS14950	COG3173	Aminoglycoside phosphotransferase
CH61_RS14965	COG1278	Cold shock
CH61_RS14975	COG5383	Protein conserved in bacteria
CH61_RS14990	COG2333	competence protein COMEC
CH61_RS14990	COG0658	competence protein
CH61_RS15000	COG0539	negative regulation of cytoplasmic translation
CH61_RS15025	COG5295	Hep Hag repeat protein
CH61_RS15025	COG5295	Hep Hag repeat protein
CH61_RS15030	COG0252	asparaginase activity
CH61_RS15035	COG1944	ATP diphosphatase activity
CH61_RS15040	COG2116	formate transmembrane transporter activity
CH61_RS15045	COG1882	Formate acetyltransferase
CH61_RS15055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CH61_RS15070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CH61_RS15080	COG1674	ftsk spoiiie
CH61_RS15080	COG3107	peptidoglycan biosynthetic process
CH61_RS15090	COG0492	ferredoxin-NADP+ reductase activity
CH61_RS15105	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CH61_RS15115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CH61_RS15125	COG0542	response to heat
CH61_RS15135	COG1278	Cold shock
CH61_RS15145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_RS15150	COG2990	Protein conserved in bacteria
CH61_RS15155	COG3593	DNA synthesis involved in DNA repair
CH61_RS15160	COG2431	L-lysine efflux transmembrane transporter activity
CH61_RS15170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_RS15175	COG0028	Belongs to the TPP enzyme family
CH61_RS15180	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CH61_RS15185	COG0702	epimerase
CH61_RS15190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CH61_RS15200	COG1605	Chorismate mutase
CH61_RS15205	COG1126	abc transporter atp-binding protein
CH61_RS15210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS15215	COG4215	(ABC) transporter
CH61_RS15220	COG4160	amino acid transport
CH61_RS15245	COG1120	ATPase activity
CH61_RS15275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS15290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS15305	COG1177	transmembrane transport
CH61_RS15310	COG1176	ABC-type spermidine putrescine transport system, permease component I
CH61_RS15315	COG3842	ATPase activity
CH61_RS15320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CH61_RS15355	COG0671	phosphoesterase, PA-phosphatase related
CH61_RS15365	COG1349	DNA-binding transcription factor activity
CH61_RS15370	COG0814	amino acid
CH61_RS15380	COG1686	Belongs to the peptidase S11 family
CH61_RS15385	COG2011	ABC-type metal ion transport system permease component
CH61_RS15410	COG0625	glutathione transferase activity
CH61_RS15415	COG4771	TonB-dependent receptor
CH61_RS15425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_RS15435	COG0833	amino acid
CH61_RS15440	COG0583	DNA-binding transcription factor activity
CH61_RS15445	COG2855	membrane
CH61_RS15455	COG3188	usher protein
CH61_RS15460	COG3121	Chaperone
CH61_RS15475	COG3710	Transcriptional regulator
CH61_RS15480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_RS15480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CH61_RS15480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_RS15485	COG1105	Belongs to the carbohydrate kinase PfkB family
CH61_RS15495	COG0494	nUDIX hydrolase
CH61_RS15505	COG1129	ABC transporter
CH61_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS15565	COG0246	Mannitol dehydrogenase
CH61_RS15570	COG2186	Transcriptional regulator
CH61_RS15580	COG0523	cobalamin synthesis protein
CH61_RS15585	COG0671	phosphoesterase, PA-phosphatase related
CH61_RS15590	COG0791	NLP P60 protein
CH61_RS15595	COG2200	EAL domain
CH61_RS15600	COG4166	transmembrane transport
CH61_RS15605	COG4174	ABC transporter (Permease)
CH61_RS15610	COG4239	(ABC) transporter, permease
CH61_RS15615	COG4172	Belongs to the ABC transporter superfamily
CH61_RS15625	COG2814	Major facilitator Superfamily
CH61_RS15630	COG1187	pseudouridine synthase activity
CH61_RS15635	COG1061	Type III restriction enzyme res subunit
CH61_RS15660	COG3082	Protein of unknown function (DUF1414)
CH61_RS15665	COG3083	sulfuric ester hydrolase activity
CH61_RS15680	COG3157	Type VI secretion system effector, Hcp
CH61_RS15700	COG2723	6-phospho-beta-galactosidase activity
CH61_RS15705	COG1737	Transcriptional regulator
CH61_RS15725	COG3299	homolog of phage Mu protein gp47
CH61_RS15765	COG4386	tail sheath protein
CH61_RS15785	COG3622	Belongs to the hyi family
CH61_RS15790	COG1349	DNA-binding transcription factor activity
CH61_RS15800	COG3395	kinase activity
CH61_RS15845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CH61_RS15885	COG2223	nitrite transmembrane transporter activity
CH61_RS15890	COG2198	Histidine kinase
CH61_RS15890	COG0642	Histidine kinase
CH61_RS15895	COG2198	Histidine kinase
CH61_RS15895	COG0642	Histidine kinase
CH61_RS15905	COG0784	Response regulator, receiver
CH61_RS15905	COG2205	protein histidine kinase activity
CH61_RS15935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CH61_RS15950	COG0814	amino acid
CH61_RS15975	COG0697	spore germination
CH61_RS15985	COG1982	Orn Lys Arg decarboxylase major
CH61_RS15990	COG0531	amino acid
CH61_RS15995	COG1174	glycine betaine transport
CH61_RS16000	COG1125	glycine betaine transport
CH61_RS16005	COG1174	glycine betaine transport
CH61_RS16010	COG1732	Glycine betaine
CH61_RS16015	COG1732	Glycine betaine
CH61_RS16020	COG2897	thiosulfate sulfurtransferase activity
CH61_RS16040	COG1122	ATPase activity
CH61_RS16060	COG4807	Protein conserved in bacteria
CH61_RS16075	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CH61_RS16085	COG2261	transglycosylase associated protein
CH61_RS16105	COG0277	FAD linked oxidase domain protein
CH61_RS16110	COG1686	Belongs to the peptidase S11 family
CH61_RS16120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH61_RS16135	COG2211	Major facilitator Superfamily
CH61_RS16140	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CH61_RS16150	COG0583	DNA-binding transcription factor activity
CH61_RS16155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CH61_RS16185	COG0670	Belongs to the BI1 family
CH61_RS16190	COG0314	molybdopterin synthase activity
CH61_RS16195	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CH61_RS16205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CH61_RS16215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CH61_RS16220	COG4628	conserved protein (DUF2132)
CH61_RS16230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CH61_RS16240	COG2226	methyltransferase
CH61_RS16265	COG0561	phosphatase activity
CH61_RS16275	COG4149	molybdate abc transporter
CH61_RS16280	COG0725	ABC transporter, periplasmic molybdate-binding protein
CH61_RS16290	COG3585	molybdate ion transport
CH61_RS16290	COG2005	Transcriptional regulator
CH61_RS16295	COG1119	ATPase activity
CH61_RS16310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CH61_RS16315	COG1085	galactose-1-phosphate uridylyltransferase
CH61_RS16330	COG2017	converts alpha-aldose to the beta-anomer
CH61_RS16345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH61_RS16360	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CH61_RS16365	COG1230	cation diffusion facilitator family transporter
CH61_RS16395	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CH61_RS16400	COG2885	chlorophyll binding
CH61_RS16410	COG3064	Membrane
CH61_RS16410	COG3064	Membrane
CH61_RS16415	COG0848	biopolymer transport protein
CH61_RS16420	COG0811	peptide transport
CH61_RS16425	COG0824	Thioesterase
CH61_RS16430	COG3790	cyd operon protein YbgE
CH61_RS16435	COG4890	Cyd operon protein YbgT
CH61_RS16440	COG1294	oxidase, subunit
CH61_RS16445	COG1271	oxidase subunit
CH61_RS16450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CH61_RS16460	COG0508	dehydrogenase complex catalyzes the overall conversion of
CH61_RS16465	COG0567	Dehydrogenase, E1 component
CH61_RS16475	COG1053	succinate dehydrogenase
CH61_RS16480	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CH61_RS16485	COG2009	succinate dehydrogenase
CH61_RS16500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CH61_RS16505	COG0497	DNA recombination
CH61_RS16510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CH61_RS16520	COG2867	negative regulation of translational initiation
CH61_RS16540	COG0582	viral genome integration into host DNA
CH61_RS16600	COG3657	addiction module killer protein
CH61_RS16630	COG1953	Uracil, thiamine, allantoin
CH61_RS16650	COG2226	methyltransferase
CH61_RS16655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CH61_RS16660	COG0741	lytic transglycosylase activity
CH61_RS16660	COG1388	LysM domain
CH61_RS16675	COG0656	L-ascorbic acid biosynthetic process
CH61_RS16710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CH61_RS16720	COG2011	ABC-type metal ion transport system permease component
CH61_RS16725	COG1464	Belongs to the NlpA lipoprotein family
CH61_RS16735	COG1720	tRNA m6t6A37 methyltransferase activity
CH61_RS16745	COG3015	lipoprotein NlpE involved in copper resistance
CH61_RS16755	COG4681	YaeQ
CH61_RS16765	COG4568	rho-dependent transcription termination
CH61_RS16775	COG0037	tRNA processing
CH61_RS16780	COG0346	lactoylglutathione lyase activity
CH61_RS16790	COG0587	DNA-directed DNA polymerase activity
CH61_RS16815	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CH61_RS16830	COG0750	zinc metalloprotease
CH61_RS16835	COG0575	Belongs to the CDS family
CH61_RS16895	COG0564	pseudouridine synthase activity
CH61_RS16900	COG3098	single-species biofilm formation
CH61_RS16920	COG1611	Belongs to the LOG family
CH61_RS16935	COG2363	Small membrane protein
CH61_RS16940	COG0583	DNA-binding transcription factor activity
CH61_RS16945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CH61_RS16950	COG2166	iron-sulfur cluster assembly
CH61_RS16955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CH61_RS16960	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CH61_RS16975	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH61_RS16985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CH61_RS16990	COG1074	ATP-dependent DNA helicase activity
CH61_RS17000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CH61_RS17035	COG4771	TonB-dependent receptor
CH61_RS17040	COG2195	Cleaves the N-terminal amino acid of tripeptides
CH61_RS17045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CH61_RS17085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_RS17095	COG5001	Diguanylate cyclase
CH61_RS17100	COG2801	Transposase and inactivated derivatives
CH61_RS17110	COG2211	Major facilitator Superfamily
CH61_RS17160	COG2771	luxR family
CH61_RS17165	COG3916	Acyl-homoserine-lactone synthase
CH61_RS17300	COG1982	Orn Lys Arg decarboxylase major
CH61_RS17305	COG1879	ABC-type sugar transport system periplasmic component
CH61_RS17310	COG1129	ABC transporter
CH61_RS17315	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS17320	COG4774	siderophore transport
CH61_RS17340	COG1194	a g-specific adenine glycosylase
CH61_RS17350	COG3171	Protein conserved in bacteria
CH61_RS17370	COG3064	Membrane
CH61_RS17370	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CH61_RS17370	COG1073	alpha beta
CH61_RS17375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH61_RS17380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CH61_RS17390	COG0762	integral membrane protein
CH61_RS17395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CH61_RS17400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CH61_RS17405	COG2805	Type II/IV secretion system protein
CH61_RS17415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CH61_RS17430	COG0189	ligase activity
CH61_RS17435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CH61_RS17440	COG2356	endonuclease I
CH61_RS17445	COG3091	SprT-like family
CH61_RS17455	COG1166	arginine decarboxylase activity
CH61_RS17465	COG0501	Belongs to the peptidase M48B family
CH61_RS17470	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CH61_RS17505	COG0191	fructose-bisphosphate aldolase activity
CH61_RS17540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CH61_RS17545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CH61_RS17560	COG0006	proline dipeptidase activity
CH61_RS17565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH61_RS17570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CH61_RS17600	COG5295	Hep Hag repeat protein
CH61_RS17610	COG1272	protein, Hemolysin III
CH61_RS17635	COG0745	RESPONSE REGULATOR receiver
CH61_RS17640	COG2205	protein histidine kinase activity
CH61_RS17645	COG4452	Inner membrane protein CreD
CH61_RS17650	COG0716	FMN binding
CH61_RS17655	COG4974	Belongs to the 'phage' integrase family
CH61_RS17660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH61_RS17665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CH61_RS17685	COG0582	viral genome integration into host DNA
CH61_RS17715	COG2944	sequence-specific DNA binding
CH61_RS17810	COG1695	Transcriptional regulator
CH61_RS17815	COG0791	NLP P60 protein
CH61_RS17825	COG1879	ABC-type sugar transport system periplasmic component
CH61_RS17830	COG1172	Belongs to the binding-protein-dependent transport system permease family
CH61_RS17835	COG1129	ABC transporter
CH61_RS17845	COG2182	Extracellular solute-binding protein
CH61_RS17850	COG1175	transmembrane transport
CH61_RS17855	COG3833	ABC-type maltose transport systems, permease component
CH61_RS17860	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CH61_RS17865	COG1874	Beta-galactosidase
CH61_RS17870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_RS17870	COG1263	PTS System
CH61_RS17890	COG2271	Major facilitator Superfamily
CH61_RS17920	COG3119	arylsulfatase activity
CH61_RS17925	COG0641	radical SAM
CH61_RS17935	COG1028	Short-chain dehydrogenase reductase Sdr
CH61_RS17945	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS17950	COG3716	PTS system mannose fructose sorbose family IID component
CH61_RS17955	COG3715	PTS system
CH61_RS17960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CH61_RS17965	COG2222	sugar isomerase
CH61_RS17975	COG1349	DNA-binding transcription factor activity
CH61_RS17980	COG3119	arylsulfatase activity
CH61_RS18035	COG0288	reversible hydration of carbon dioxide
CH61_RS18055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CH61_RS18125	COG0840	transmembrane signaling receptor activity
CH61_RS18140	COG0583	DNA-binding transcription factor activity
CH61_RS18145	COG2814	Major facilitator Superfamily
CH61_RS18150	COG0583	DNA-binding transcription factor activity
CH61_RS18160	COG1609	Transcriptional regulator
CH61_RS18190	COG0667	Aldo Keto reductase
CH61_RS18250	COG3433	isochorismatase activity
CH61_RS18250	COG2226	methyltransferase
CH61_RS18250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_RS18260	COG2226	methyltransferase
CH61_RS18260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CH61_RS18260	COG3433	isochorismatase activity
CH61_RS18285	COG2375	cellular response to nickel ion
CH61_RS18285	COG1132	(ABC) transporter
CH61_RS18290	COG1132	(ABC) transporter
CH61_RS18305	COG2610	gluconate transmembrane transporter activity
CH61_RS18320	COG3501	Rhs element vgr protein
CH61_RS18330	COG3209	COG3209 Rhs family protein
CH61_RS18345	COG0471	metal ion transport
CH61_RS18405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CH61_RS18410	COG1191	sigma factor activity
CH61_RS18435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CH61_RS18455	COG3710	Transcriptional regulator
CH61_RS18475	COG1256	bacterial-type flagellum assembly
CH61_RS18485	COG1706	bacterial-type flagellum-dependent cell motility
CH61_RS18495	COG4786	Flagellar basal body rod
CH61_RS18520	COG1749	Flagellar hook protein flgE
CH61_RS18525	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CH61_RS18530	COG1558	bacterial-type flagellum-dependent cell motility
CH61_RS18535	COG1815	bacterial-type flagellum-dependent cell motility
CH61_RS18540	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CH61_RS18580	COG1677	Flagellar hook-basal body complex protein FliE
CH61_RS18605	COG1987	bacterial-type flagellum assembly
CH61_RS18610	COG1684	flagellar biosynthetic protein fliR
CH61_RS18615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CH61_RS18635	COG4592	Periplasmic binding protein
CH61_RS18680	COG4964	Belongs to the GSP D family
CH61_RS18685	COG4964	Belongs to the GSP D family
CH61_RS18735	COG0848	biopolymer transport protein
CH61_RS18740	COG0811	peptide transport
CH61_RS18745	COG0626	cystathionine gamma-synthase activity
CH61_RS18750	COG0586	Pfam SNARE associated Golgi protein
CH61_RS18755	COG2207	Transcriptional regulator
CH61_RS18760	COG1979	alcohol dehydrogenase
CH61_RS18770	COG0656	L-ascorbic acid biosynthetic process
CH61_RS18780	COG2132	Multicopper oxidase
CH61_RS18790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CH61_RS18800	COG2249	NAD(P)H dehydrogenase (quinone) activity
CH61_RS18805	COG0583	DNA-binding transcription factor activity
CH61_RS18815	COG3150	esterase
CH61_RS18820	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CH61_RS18825	COG3151	Protein conserved in bacteria
CH61_RS18830	COG0494	nUDIX hydrolase
CH61_RS18835	COG1538	Outer membrane efflux protein
CH61_RS18850	COG0754	glutathionylspermidine amidase activity
CH61_RS18855	COG3384	dioxygenase
CH61_RS18875	COG0531	amino acid
CH61_RS18890	COG3025	triphosphatase activity
CH61_RS18895	COG4991	sh3 domain protein
CH61_RS18910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CH61_RS18925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CH61_RS18930	COG0358	DNA primase activity
CH61_RS19025	COG0251	oxidation-reduction process
CH61_RS19045	COG0436	Aminotransferase
CH61_RS19070	COG1289	transmembrane transporter activity
CH61_RS19090	COG0395	ABC-type sugar transport system, permease component
CH61_RS19100	COG2182	Extracellular solute-binding protein
CH61_RS19105	COG1609	Transcriptional regulator
CH61_RS19110	COG3459	Glycosyltransferase 36 associated
CH61_RS19115	COG3842	ATPase activity
CH61_RS19135	COG3210	domain, Protein
CH61_RS19140	COG3210	domain, Protein
CH61_RS19165	COG3210	domain, Protein
CH61_RS19170	COG2831	hemolysin activation secretion protein
CH61_RS19175	COG4245	von Willebrand factor, type A
CH61_RS19190	COG4245	von Willebrand factor, type A
CH61_RS19210	COG3247	response to pH
CH61_RS19215	COG0446	pyridine nucleotide-disulphide oxidoreductase
CH61_RS19215	COG1902	pentaerythritol trinitrate reductase activity
CH61_RS19230	COG1451	nucleotide metabolic process
CH61_RS19235	COG0673	inositol 2-dehydrogenase activity
CH61_RS19260	COG2721	sulfolactate sulfo-lyase activity
CH61_RS19280	COG2271	Major facilitator Superfamily
CH61_RS19295	COG0586	Pfam SNARE associated Golgi protein
CH61_RS19315	COG4575	ribosome binding
CH61_RS19320	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CH61_RS19330	COG2259	Doxx family
CH61_RS19335	COG0435	Glutathione S-transferase
CH61_RS19350	COG0494	nUDIX hydrolase
CH61_RS19375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CH61_RS19380	COG0849	cell division
CH61_RS19385	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CH61_RS19405	COG0772	Belongs to the SEDS family
CH61_RS19420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CH61_RS19425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CH61_RS19430	COG0768	penicillin binding
CH61_RS19435	COG3116	cell division
CH61_RS19455	COG1609	Transcriptional regulator
CH61_RS19475	COG0028	Belongs to the TPP enzyme family
CH61_RS19485	COG1022	Amp-dependent synthetase and ligase
CH61_RS19520	COG0473	3-isopropylmalate dehydrogenase activity
CH61_RS19535	COG2814	Major facilitator Superfamily
CH61_RS19555	COG2814	Major facilitator Superfamily
CH61_RS19575	COG4143	(ABC) transporter
CH61_RS19580	COG1178	ABC-type Fe3 transport system permease component
CH61_RS19585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CH61_RS19590	COG0586	Pfam SNARE associated Golgi protein
CH61_RS19595	COG0417	DNA replication proofreading
CH61_RS19615	COG3047	cAMP biosynthetic process
CH61_RS19615	COG2885	chlorophyll binding
CH61_RS19705	COG0564	pseudouridine synthase activity
CH61_RS19710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CH61_RS19760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CH61_RS19770	COG2966	Psort location CytoplasmicMembrane, score
CH61_RS19775	COG1280	lysine exporter protein (LysE YggA)
CH61_RS19780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CH61_RS19825	COG1047	Peptidyl-prolyl cis-trans
CH61_RS19840	COG0196	riboflavin kinase activity
CH61_RS19855	COG0583	DNA-binding transcription factor activity
CH61_RS19875	COG1584	GPR1 FUN34 yaaH family protein
CH61_RS19890	COG0521	Mo-molybdopterin cofactor biosynthetic process
CH61_RS19920	COG0745	RESPONSE REGULATOR receiver
CH61_RS19925	COG3045	CreA protein
CH61_RS19930	COG2207	Transcriptional regulator
CH61_RS19930	COG3708	Transcriptional regulator
CH61_RS19945	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
CH61_RS19950	COG0741	lytic transglycosylase activity
CH61_RS19965	COG2199	diguanylate cyclase activity
CH61_RS19970	COG2885	chlorophyll binding
CH61_RS19995	COG0560	Phosphoserine phosphatase
CH61_RS20000	COG3726	membrane protein affecting hemolysin expression
CH61_RS20030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CH61_RS20035	COG0084	hydrolase, TatD family'
CH61_RS20040	COG4667	esterase of the alpha-beta hydrolase superfamily
CH61_RS20050	COG2823	Periplasmic or secreted lipoprotein
CH61_RS20060	COG0456	acetyltransferase
CH61_RS20065	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CH61_RS20110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CH61_RS20115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CH61_RS20135	COG0859	PFAM glycosyl transferase family 9
CH61_RS20140	COG1070	Carbohydrate kinase
CH61_RS20190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS20190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CH61_RS20190	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CH61_RS20195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_RS20200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_RS20205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CH61_RS20210	COG2207	Transcriptional regulator
CH61_RS20220	COG4269	membrane
CH61_RS20275	COG2963	transposase activity
CH61_RS20290	COG1401	restriction endodeoxyribonuclease activity
CH61_RS20315	COG3650	response to hydrogen peroxide
CH61_RS20320	COG1960	acyl-CoA dehydrogenase activity
CH61_RS20325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH61_RS20330	COG0557	exoribonuclease II activity
CH61_RS20345	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CH61_RS20350	COG0330	HflC and HflK could
CH61_RS20355	COG0330	HflC and HflK could
CH61_RS20360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CH61_RS20380	COG0860	N-Acetylmuramoyl-L-alanine amidase
CH61_RS20385	COG0802	atpase or kinase
CH61_RS20390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CH61_RS20390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CH61_RS20395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CH61_RS20410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CH61_RS20430	COG1511	domain protein
CH61_RS20430	COG3264	Mechanosensitive ion channel
CH61_RS20445	COG1053	succinate dehydrogenase
CH61_RS20450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CH61_RS20460	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CH61_RS20515	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CH61_RS20530	COG3383	formate dehydrogenase (NAD+) activity
CH61_RS20535	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_RS20540	COG0493	'glutamate synthase
CH61_RS20540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CH61_RS20545	COG1309	transcriptional regulator
CH61_RS20615	COG1454	alcohol dehydrogenase
CH61_RS20625	COG0629	single-stranded DNA binding
CH61_RS20630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CH61_RS20635	COG2315	Protein conserved in bacteria
CH61_RS20640	COG1448	Aminotransferase
CH61_RS20665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CH61_RS20670	COG0735	belongs to the Fur family
CH61_RS20680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CH61_RS20725	COG3121	Chaperone
CH61_RS20785	COG1358	cellular component organization or biogenesis
CH61_RS20810	COG3721	Heme iron utilization protein
CH61_RS20815	COG0702	epimerase
CH61_RS20820	COG4771	TonB-dependent receptor
CH61_RS20825	COG3720	iron ion transport
CH61_RS20830	COG4558	Periplasmic binding protein
CH61_RS20835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CH61_RS20845	COG0626	cystathionine gamma-synthase activity
CH61_RS20850	COG0814	amino acid
CH61_RS20855	COG0583	DNA-binding transcription factor activity
CH61_RS20860	COG0425	Belongs to the sulfur carrier protein TusA family
CH61_RS20865	COG2391	methyltransferase activity
CH61_RS20975	COG1301	dicarboxylic acid transport
CH61_RS20985	COG3162	membrane
CH61_RS21010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CH61_RS21025	COG0551	DNA topoisomerase type I activity
CH61_RS21035	COG0758	DNA mediated transformation
CH61_RS21065	COG3036	rescue of stalled ribosome
CH61_RS21070	COG0789	Transcriptional regulator
CH61_RS21085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CH61_RS21100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CH61_RS21105	COG0201	protein transport
CH61_RS21115	COG1841	ribosomal large subunit assembly
CH61_RS21155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CH61_RS21160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CH61_RS21170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CH61_RS21175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CH61_RS21185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CH61_RS21195	COG0089	rRNA binding
CH61_RS21210	COG0051	transcription antitermination factor activity, RNA binding
CH61_RS21240	COG0049	tRNA binding
CH61_RS21245	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CH61_RS21265	COG2964	Protein conserved in bacteria
CH61_RS21270	COG0545	Peptidyl-prolyl cis-trans isomerase
CH61_RS21280	COG1047	Peptidyl-prolyl cis-trans
CH61_RS21285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CH61_RS21305	COG1216	Glycosyl transferase, family 2
CH61_RS21315	COG2175	clavaminate synthase activity
CH61_RS21320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CH61_RS21330	COG4521	taurine ABC transporter
CH61_RS21340	COG0429	hydrolase of the alpha beta-hydrolase fold
CH61_RS21350	COG3954	Phosphoribulokinase
CH61_RS21360	COG1765	OsmC-like protein
CH61_RS21370	COG1289	transmembrane transporter activity
CH61_RS21385	COG0433	COG0433 Predicted ATPase
CH61_RS21395	COG1486	melibiose metabolic process
CH61_RS21415	COG0402	S-adenosylhomocysteine deaminase activity
CH61_RS21420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CH61_RS21440	COG0180	Tryptophanyl-tRNA synthetase
CH61_RS21445	COG0546	phosphoglycolate phosphatase activity
CH61_RS21450	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CH61_RS21475	COG4796	Type ii and iii secretion system protein
CH61_RS21505	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CH61_RS21510	COG0494	nUDIX hydrolase
CH61_RS21525	COG1011	Hydrolase
CH61_RS21530	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CH61_RS21555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CH61_RS21560	COG2183	response to ionizing radiation
CH61_RS21570	COG1918	ferrous iron import across plasma membrane
CH61_RS21605	COG1640	4-alpha-glucanotransferase
CH61_RS21610	COG0058	SHG alpha-glucan phosphorylase activity
CH61_RS21615	COG0058	SHG alpha-glucan phosphorylase activity
CH61_RS21625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH61_RS21635	COG1349	DNA-binding transcription factor activity
CH61_RS21645	COG2801	Transposase and inactivated derivatives
CH61_RS21655	COG0460	homoserine dehydrogenase
CH61_RS21655	COG0527	aspartate kinase activity
CH61_RS21675	COG4682	membrane
CH61_RS21685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CH61_RS21695	COG1609	Transcriptional regulator
CH61_RS21700	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CH61_RS21715	COG1575	Belongs to the MenA family. Type 1 subfamily
CH61_RS21780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CH61_RS21785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CH61_RS21790	COG1494	fructose-1,6-bisphosphatase
CH61_RS21800	COG3152	Membrane
CH61_RS21815	COG0583	DNA-binding transcription factor activity
CH61_RS21820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CH61_RS21825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CH61_RS21830	COG0471	metal ion transport
CH61_RS21840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CH61_RS21860	COG3678	ATP-independent chaperone mediated protein folding
CH61_RS21865	COG0745	RESPONSE REGULATOR receiver
CH61_RS21870	COG2205	protein histidine kinase activity
CH61_RS21875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CH61_RS21875	COG2169	Transcriptional regulator
CH61_RS21880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CH61_RS21885	COG1045	serine acetyltransferase
CH61_RS21905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CH61_RS21910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CH61_RS21920	COG4942	peptidase
CH61_RS21935	COG0156	8-amino-7-oxononanoate synthase activity
CH61_RS21945	COG0859	PFAM glycosyl transferase family 9
CH61_RS21950	COG0859	PFAM glycosyl transferase family 9
CH61_RS21955	COG1519	Transferase
CH61_RS21990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CH61_RS22015	COG1561	YicC-like family, N-terminal region
CH61_RS22020	COG2860	membrane
CH61_RS22040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CH61_RS22045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CH61_RS22050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CH61_RS22055	COG0786	glutamate:sodium symporter activity
CH61_RS22060	COG2233	PERMEase
CH61_RS22065	COG2982	Protein involved in outer membrane biogenesis
CH61_RS22070	COG0456	acetyltransferase
CH61_RS22095	COG1011	Hydrolase
CH61_RS22110	COG0174	glutamine synthetase
CH61_RS22115	COG3852	Histidine kinase
CH61_RS22125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CH61_RS22150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH61_RS22150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CH61_RS22155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CH61_RS22160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CH61_RS22165	COG3084	Protein conserved in bacteria
CH61_RS22175	COG1763	Mo-molybdopterin cofactor biosynthetic process
CH61_RS22210	COG2186	Transcriptional regulator
CH61_RS22215	COG0477	Major facilitator Superfamily
CH61_RS22225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CH61_RS22255	COG1522	sequence-specific DNA binding
CH61_RS22260	COG0716	FMN binding
CH61_RS22275	COG3312	ion transport
CH61_RS22330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CH61_RS22335	COG0573	inorganic phosphate transmembrane transporter activity
CH61_RS22340	COG0581	inorganic phosphate transmembrane transporter activity
CH61_RS22350	COG0704	Plays a role in the regulation of phosphate uptake
CH61_RS22360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CH61_RS22365	COG0765	amino acid transport
CH61_RS22370	COG0765	amino acid transport
CH61_RS22375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CH61_RS22380	COG2252	PERMEase