locus-tag	class	description
AH66_RS00010	COG0592	DNA-directed DNA polymerase activity
AH66_RS00020	COG0187	DNA topoisomerase II activity
AH66_RS00025	COG0561	phosphatase activity
AH66_RS00035	COG2423	ornithine cyclodeaminase activity
AH66_RS00040	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AH66_RS00050	COG5645	(Lipo)protein
AH66_RS00070	COG3977	Valine--pyruvate aminotransferase
AH66_RS00080	COG0366	Alpha amylase catalytic
AH66_RS00095	COG2885	chlorophyll binding
AH66_RS00105	COG2818	Glycosylase
AH66_RS00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS00130	COG2213	PTS system mannitol-specific
AH66_RS00140	COG3722	fumarate hydratase activity
AH66_RS00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AH66_RS00180	COG0437	4 iron, 4 sulfur cluster binding
AH66_RS00185	COG2864	formate dehydrogenase
AH66_RS00245	COG3274	enterobacterial common antigen metabolic process
AH66_RS00260	COG3121	Chaperone
AH66_RS00270	COG1070	Carbohydrate kinase
AH66_RS00280	COG4213	ABC transporter substrate-binding protein
AH66_RS00290	COG4214	carbohydrate transport
AH66_RS00295	COG2207	Transcriptional regulator
AH66_RS00295	COG1609	Transcriptional regulator
AH66_RS00305	COG0582	viral genome integration into host DNA
AH66_RS00350	COG4604	ABC transporter, ATP-binding protein
AH66_RS00355	COG4605	iron ion homeostasis
AH66_RS00365	COG4607	ABC-type enterochelin transport system periplasmic component
AH66_RS00395	COG2986	histidine ammonia-lyase
AH66_RS00410	COG2194	sulfuric ester hydrolase activity
AH66_RS00415	COG2197	response regulator
AH66_RS00420	COG3851	Histidine kinase
AH66_RS00425	COG2271	Major facilitator Superfamily
AH66_RS00440	COG2831	hemolysin activation secretion protein
AH66_RS00445	COG0747	negative chemotaxis
AH66_RS00455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_RS00460	COG0444	Belongs to the ABC transporter superfamily
AH66_RS00465	COG4608	Belongs to the ABC transporter superfamily
AH66_RS00470	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AH66_RS00475	COG2199	diguanylate cyclase activity
AH66_RS00475	COG2200	EAL domain
AH66_RS00480	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AH66_RS00500	COG0612	Peptidase, M16
AH66_RS00505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_RS00510	COG1942	4-Oxalocrotonate Tautomerase
AH66_RS00515	COG2200	EAL domain
AH66_RS00520	COG2982	Protein involved in outer membrane biogenesis
AH66_RS00525	COG2134	cdp-diacylglycerol pyrophosphatase
AH66_RS00530	COG1295	ribonuclease BN
AH66_RS00555	COG1929	Belongs to the glycerate kinase type-1 family
AH66_RS00560	COG2610	gluconate transmembrane transporter activity
AH66_RS00570	COG3835	regulator
AH66_RS00575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AH66_RS00580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AH66_RS00585	COG0339	signal peptide processing
AH66_RS00605	COG0589	response to stress
AH66_RS00620	COG0306	phosphate transporter
AH66_RS00625	COG2081	HI0933 family
AH66_RS00640	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS00655	COG0191	fructose-bisphosphate aldolase activity
AH66_RS00675	COG1741	Belongs to the pirin family
AH66_RS00680	COG1609	Transcriptional regulator
AH66_RS00685	COG2610	gluconate transmembrane transporter activity
AH66_RS00690	COG3265	gluconokinase activity
AH66_RS00705	COG2095	MarC family integral membrane protein
AH66_RS00710	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AH66_RS00745	COG3275	phosphorelay sensor kinase activity
AH66_RS00770	COG0058	SHG alpha-glucan phosphorylase activity
AH66_RS00775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AH66_RS00825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AH66_RS00840	COG1629	transport
AH66_RS00865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AH66_RS00870	COG0678	peroxiredoxin activity
AH66_RS00870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AH66_RS00940	COG1879	ABC-type sugar transport system periplasmic component
AH66_RS00945	COG1129	ABC transporter
AH66_RS00950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS00955	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS00965	COG3085	chromosome segregation
AH66_RS00985	COG3978	acetolactate synthase activity
AH66_RS00990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AH66_RS01035	COG0583	DNA-binding transcription factor activity
AH66_RS01070	COG3121	Chaperone
AH66_RS01085	COG3121	Chaperone
AH66_RS01095	COG3328	transposase activity
AH66_RS01105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AH66_RS01130	COG3118	belongs to the thioredoxin family
AH66_RS01135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AH66_RS01140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AH66_RS01145	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AH66_RS01150	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AH66_RS01155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AH66_RS01160	COG1088	dTDP-glucose 4,6-dehydratase activity
AH66_RS01165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AH66_RS01170	COG0456	acetyltransferase
AH66_RS01175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AH66_RS01180	COG2244	polysaccharide biosynthetic process
AH66_RS01200	COG1113	amino acid transport
AH66_RS01230	COG3071	HemY protein
AH66_RS01235	COG2959	enzyme of heme biosynthesis
AH66_RS01240	COG1587	Uroporphyrinogen-III synthase
AH66_RS01255	COG3072	Adenylate cyclase
AH66_RS01275	COG3159	Protein conserved in bacteria
AH66_RS01280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AH66_RS01285	COG1011	Hydrolase
AH66_RS01290	COG0210	DNA helicase
AH66_RS01300	COG5441	Belongs to the UPF0261 family
AH66_RS01305	COG5564	TIM-barrel signal transduction protein
AH66_RS01320	COG2050	protein possibly involved in aromatic compounds catabolism
AH66_RS01325	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
AH66_RS01330	COG0514	ATP-dependent DNA helicase (RecQ)
AH66_RS01335	COG1280	lysine exporter protein (LysE YggA)
AH66_RS01340	COG1280	lysine exporter protein (LysE YggA)
AH66_RS01345	COG2267	carboxylic ester hydrolase activity
AH66_RS01350	COG0561	phosphatase activity
AH66_RS01360	COG0584	glycerophosphoryl diester phosphodiesterase
AH66_RS01365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AH66_RS01375	COG0247	lactate metabolic process
AH66_RS01385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AH66_RS01400	COG3714	YhhN family
AH66_RS01415	COG3776	membrane
AH66_RS01420	COG0742	ribosomal rna small subunit methyltransferase
AH66_RS01425	COG0552	protein localization to endoplasmic reticulum
AH66_RS01425	COG0552	protein localization to endoplasmic reticulum
AH66_RS01430	COG2884	Cell division ATP-binding protein ftsE
AH66_RS01435	COG2177	Part of the ABC transporter FtsEX involved in
AH66_RS01455	COG0683	leucine binding
AH66_RS01465	COG4177	L-phenylalanine transmembrane transporter activity
AH66_RS01475	COG0410	ABC transporter
AH66_RS01535	COG0584	glycerophosphoryl diester phosphodiesterase
AH66_RS01540	COG0679	Auxin Efflux Carrier
AH66_RS01545	COG0697	spore germination
AH66_RS01550	COG0583	DNA-binding transcription factor activity
AH66_RS01560	COG0412	Dienelactone hydrolase
AH66_RS01575	COG1966	Carbon starvation protein
AH66_RS01580	COG0586	Pfam SNARE associated Golgi protein
AH66_RS01585	COG1322	Protein conserved in bacteria
AH66_RS01605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AH66_RS01615	COG0805	protein transport
AH66_RS01650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AH66_RS01675	COG1739	Uncharacterized protein family UPF0029
AH66_RS01690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AH66_RS01695	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AH66_RS01725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AH66_RS01785	COG0250	Participates in transcription elongation, termination and antitermination
AH66_RS01830	COG2022	thiamine diphosphate biosynthetic process
AH66_RS01840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AH66_RS01875	COG1515	deoxyribonuclease V activity
AH66_RS01895	COG0151	Belongs to the GarS family
AH66_RS01945	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AH66_RS01950	COG2224	Isocitrate lyase
AH66_RS01980	COG0527	aspartate kinase activity
AH66_RS01995	COG3833	ABC-type maltose transport systems, permease component
AH66_RS02000	COG1175	transmembrane transport
AH66_RS02130	COG3501	Rhs element vgr protein
AH66_RS02175	COG3501	Rhs element vgr protein
AH66_RS02185	COG3209	COG3209 Rhs family protein
AH66_RS02205	COG0673	inositol 2-dehydrogenase activity
AH66_RS02210	COG2207	Transcriptional regulator
AH66_RS02210	COG1917	Cupin 2, conserved barrel domain protein
AH66_RS02215	COG1869	D-ribose catabolic process
AH66_RS02220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_RS02225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AH66_RS02230	COG0431	NADPH-dependent FMN reductase
AH66_RS02235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AH66_RS02245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AH66_RS02260	COG3077	Addiction module antitoxin, RelB DinJ family
AH66_RS02265	COG2252	PERMEase
AH66_RS02270	COG0025	NhaP-type Na H and K H
AH66_RS02280	COG1560	Kdo2-lipid A biosynthetic process
AH66_RS02290	COG1129	ABC transporter
AH66_RS02295	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS02305	COG1069	ribulokinase activity
AH66_RS02315	COG0625	glutathione transferase activity
AH66_RS02335	COG1278	Cold shock
AH66_RS02340	COG1278	Cold shock
AH66_RS02345	COG3133	Outer membrane lipoprotein
AH66_RS02350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AH66_RS02360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AH66_RS02390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AH66_RS02395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AH66_RS02405	COG4145	pantothenate transmembrane transporter activity
AH66_RS02410	COG3924	membrane
AH66_RS02420	COG0439	Biotin carboxylase
AH66_RS02425	COG0511	ligase activity, forming carbon-carbon bonds
AH66_RS02440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AH66_RS02445	COG0604	alcohol dehydrogenase
AH66_RS02450	COG2199	diguanylate cyclase activity
AH66_RS02450	COG2200	EAL domain
AH66_RS02455	COG1077	Cell shape determining protein MreB Mrl
AH66_RS02460	COG1792	Involved in formation and maintenance of cell shape
AH66_RS02465	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AH66_RS02470	COG0424	maF-like protein
AH66_RS02475	COG1530	ribonuclease E activity
AH66_RS02480	COG3164	Protein of unknown function
AH66_RS02485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AH66_RS02490	COG0312	modulator of DNA gyrase
AH66_RS02545	COG0583	DNA-binding transcription factor activity
AH66_RS02575	COG2732	(Barnase) inhibitor
AH66_RS02585	COG0312	modulator of DNA gyrase
AH66_RS02595	COG3783	Cytochrome b(562)
AH66_RS02600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AH66_RS02605	COG0366	Alpha amylase catalytic
AH66_RS02610	COG1263	PTS System
AH66_RS02610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_RS02615	COG1609	Transcriptional regulator
AH66_RS02650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS02670	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AH66_RS02675	COG1137	ATPase activity
AH66_RS02680	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AH66_RS02685	COG3117	lipopolysaccharide transmembrane transporter activity
AH66_RS02690	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AH66_RS02695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AH66_RS02695	COG0517	IMP dehydrogenase activity
AH66_RS02700	COG0530	calcium, potassium:sodium antiporter activity
AH66_RS02705	COG1127	ABC transporter
AH66_RS02710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AH66_RS02715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AH66_RS02720	COG2854	intermembrane phospholipid transfer
AH66_RS02725	COG3113	response to antibiotic
AH66_RS02730	COG5007	Belongs to the BolA IbaG family
AH66_RS02740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AH66_RS02750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AH66_RS02755	COG3105	Protein conserved in bacteria
AH66_RS02760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AH66_RS02780	COG0625	glutathione transferase activity
AH66_RS02785	COG2969	positive regulation of protein catabolic process
AH66_RS02795	COG0493	'glutamate synthase
AH66_RS02800	COG0070	glutamate synthase
AH66_RS02800	COG0067	glutamate synthase
AH66_RS02800	COG0069	glutamate synthase activity
AH66_RS02805	COG1242	4 iron, 4 sulfur cluster binding
AH66_RS02810	COG2198	Histidine kinase
AH66_RS02810	COG0784	Response regulator, receiver
AH66_RS02810	COG5002	protein histidine kinase activity
AH66_RS02815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AH66_RS02825	COG2823	Periplasmic or secreted lipoprotein
AH66_RS02845	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AH66_RS02855	COG1741	Belongs to the pirin family
AH66_RS02860	COG0583	DNA-binding transcription factor activity
AH66_RS02905	COG1459	type II secretion system
AH66_RS02910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AH66_RS02915	COG4969	Belongs to the N-Me-Phe pilin family
AH66_RS02925	COG3023	N-Acetylmuramoyl-L-alanine amidase
AH66_RS02930	COG3725	Membrane protein required for beta-lactamase induction
AH66_RS02935	COG1113	amino acid transport
AH66_RS02940	COG2186	Transcriptional regulator
AH66_RS02945	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AH66_RS02950	COG0508	dehydrogenase complex catalyzes the overall conversion of
AH66_RS02955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AH66_RS02965	COG1049	propionate catabolic process, 2-methylcitrate cycle
AH66_RS02975	COG0697	spore germination
AH66_RS02995	COG2132	Multicopper oxidase
AH66_RS03000	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AH66_RS03005	COG0288	reversible hydration of carbon dioxide
AH66_RS03010	COG1131	(ABC) transporter
AH66_RS03015	COG0842	Transport permease protein
AH66_RS03020	COG0726	polysaccharide deacetylase
AH66_RS03040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AH66_RS03045	COG0617	tRNA 3'-terminal CCA addition
AH66_RS03050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AH66_RS03065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AH66_RS03070	COG1643	Atp-dependent helicase
AH66_RS03075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AH66_RS03080	COG1120	ATPase activity
AH66_RS03085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AH66_RS03090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS03110	COG2860	membrane
AH66_RS03130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AH66_RS03135	COG3850	Histidine kinase
AH66_RS03135	COG3437	response regulator, receiver
AH66_RS03135	COG4999	Histidine kinase
AH66_RS03135	COG2205	protein histidine kinase activity
AH66_RS03145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AH66_RS03150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AH66_RS03155	COG3956	TIGRFAM MazG family protein
AH66_RS03175	COG0602	queuosine metabolic process
AH66_RS03180	COG0720	synthase
AH66_RS03235	COG0529	Catalyzes the synthesis of activated sulfate
AH66_RS03275	COG4942	peptidase
AH66_RS03275	COG1388	LysM domain
AH66_RS03280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AH66_RS03290	COG0698	ribose 5-phosphate isomerase
AH66_RS03295	COG1063	alcohol dehydrogenase
AH66_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS03305	COG2376	Dihydroxyacetone kinase
AH66_RS03320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AH66_RS03340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_RS03345	COG1858	cytochrome C peroxidase
AH66_RS03355	COG4771	TonB-dependent receptor
AH66_RS03370	COG0024	Methionine aminopeptidase
AH66_RS03380	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AH66_RS03380	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AH66_RS03385	COG1070	Carbohydrate kinase
AH66_RS03390	COG3623	hexulose-6-phosphate isomerase
AH66_RS03395	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS03400	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS03405	COG1129	ABC transporter
AH66_RS03420	COG1349	DNA-binding transcription factor activity
AH66_RS03425	COG0235	Class ii aldolase
AH66_RS03430	COG0243	molybdopterin cofactor binding
AH66_RS03435	COG0437	4 iron, 4 sulfur cluster binding
AH66_RS03440	COG3302	dmso reductase anchor subunit
AH66_RS03445	COG3381	protein complex oligomerization
AH66_RS03450	COG3038	cytochrome b561
AH66_RS03455	COG3783	Cytochrome b(562)
AH66_RS03465	COG1879	ABC-type sugar transport system periplasmic component
AH66_RS03475	COG1129	ABC transporter
AH66_RS03480	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS03485	COG3959	Transketolase, thiamine diphosphate binding domain
AH66_RS03490	COG3958	Transketolase
AH66_RS03495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AH66_RS03535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AH66_RS03540	COG3328	transposase activity
AH66_RS03575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_RS03580	COG1238	metal cluster binding
AH66_RS03585	COG2918	glutathione biosynthetic process
AH66_RS03605	COG4536	flavin adenine dinucleotide binding
AH66_RS03610	COG4137	Cytochrome C assembly protein
AH66_RS03615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AH66_RS03645	COG3137	Salt-induced outer membrane protein
AH66_RS03655	COG3279	Response regulator of the LytR AlgR family
AH66_RS03660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AH66_RS03665	COG1605	Chorismate mutase
AH66_RS03665	COG0287	Prephenate dehydrogenase
AH66_RS03670	COG1605	Chorismate mutase
AH66_RS03670	COG0077	Prephenate dehydratase
AH66_RS03685	COG1073	alpha beta
AH66_RS03690	COG0360	Binds together with S18 to 16S ribosomal RNA
AH66_RS03700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AH66_RS03720	COG3061	Opacity-associated protein A
AH66_RS03725	COG0545	Peptidyl-prolyl cis-trans isomerase
AH66_RS03735	COG0737	Belongs to the 5'-nucleotidase family
AH66_RS03745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AH66_RS03755	COG1253	flavin adenine dinucleotide binding
AH66_RS03765	COG0729	surface antigen
AH66_RS03770	COG2911	Protein conserved in bacteria
AH66_RS03775	COG2105	PFAM AIG2 family protein
AH66_RS03780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AH66_RS03785	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AH66_RS03790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AH66_RS03810	COG3423	Transcriptional regulator
AH66_RS03820	COG0142	geranyltranstransferase activity
AH66_RS03835	COG0697	spore germination
AH66_RS03845	COG0642	Histidine kinase
AH66_RS03850	COG0745	RESPONSE REGULATOR receiver
AH66_RS03855	COG2027	D-alanyl-D-alanine carboxypeptidase
AH66_RS03865	COG1534	Rna-binding protein
AH66_RS03880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AH66_RS03890	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AH66_RS03910	COG0195	Participates in both transcription termination and antitermination
AH66_RS03955	COG0513	Belongs to the DEAD box helicase family
AH66_RS03975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AH66_RS03985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_RS03995	COG0826	peptidase U32
AH66_RS04000	COG0826	peptidase U32
AH66_RS04005	COG3154	lipid carrier protein
AH66_RS04010	COG3153	acetyltransferase
AH66_RS04030	COG1653	transport
AH66_RS04035	COG1175	transmembrane transport
AH66_RS04040	COG0395	ABC-type sugar transport system, permease component
AH66_RS04045	COG3842	ATPase activity
AH66_RS04060	COG0702	epimerase
AH66_RS04065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AH66_RS04070	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AH66_RS04075	COG3454	Phosphonate metabolism
AH66_RS04080	COG4778	phosphonate C-P lyase system protein PhnL
AH66_RS04085	COG4107	phosphonate C-P lyase system protein PhnK
AH66_RS04090	COG3627	carbon phosphorus lyase activity
AH66_RS04095	COG3626	phosphonate metabolism
AH66_RS04100	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AH66_RS04105	COG3624	Phosphonate C-P lyase system protein PhnG
AH66_RS04110	COG2188	Transcriptional regulator
AH66_RS04125	COG4608	Belongs to the ABC transporter superfamily
AH66_RS04130	COG0444	Belongs to the ABC transporter superfamily
AH66_RS04135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_RS04140	COG0601	transmembrane transport
AH66_RS04150	COG2731	YhcH YjgK YiaL family protein
AH66_RS04160	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AH66_RS04170	COG0525	valine-tRNA ligase activity
AH66_RS04175	COG2927	DNA polymerase III (CHI subunit)
AH66_RS04185	COG0795	lipopolysaccharide-transporting ATPase activity
AH66_RS04190	COG0795	lipopolysaccharide-transporting ATPase activity
AH66_RS04200	COG0582	viral genome integration into host DNA
AH66_RS04235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AH66_RS04240	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH66_RS04245	COG0564	pseudouridine synthase activity
AH66_RS04255	COG0542	response to heat
AH66_RS04285	COG5544	Lipoprotein
AH66_RS04290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AH66_RS04295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AH66_RS04295	COG1042	CoA-binding domain protein
AH66_RS04295	COG0045	succinate-CoA ligase (ADP-forming) activity
AH66_RS04300	COG3148	PFAM DTW domain containing protein
AH66_RS04305	COG3118	belongs to the thioredoxin family
AH66_RS04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AH66_RS04315	COG2814	Major facilitator Superfamily
AH66_RS04320	COG1566	PFAM secretion protein HlyD family protein
AH66_RS04325	COG1846	Transcriptional regulator
AH66_RS04335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AH66_RS04340	COG2814	Major facilitator Superfamily
AH66_RS04375	COG0765	amino acid transport
AH66_RS04385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AH66_RS04400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AH66_RS04425	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
AH66_RS04435	COG1960	acyl-CoA dehydrogenase activity
AH66_RS04445	COG0121	glutamine amidotransferase
AH66_RS04450	COG3034	peptidoglycan biosynthetic process
AH66_RS04460	COG1805	sodium ion transport
AH66_RS04465	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AH66_RS04485	COG1477	protein flavinylation
AH66_RS04505	COG2195	Cleaves the N-terminal amino acid of tripeptides
AH66_RS04510	COG0583	DNA-binding transcription factor activity
AH66_RS04560	COG2226	methyltransferase
AH66_RS04585	COG1940	carbohydrate kinase activity
AH66_RS04600	COG0419	ATPase involved in DNA repair
AH66_RS04605	COG0420	3'-5' exonuclease activity
AH66_RS04610	COG0745	RESPONSE REGULATOR receiver
AH66_RS04615	COG5002	protein histidine kinase activity
AH66_RS04635	COG0366	Alpha amylase catalytic
AH66_RS04660	COG0450	alkyl hydroperoxide reductase
AH66_RS04680	COG1862	Preprotein translocase
AH66_RS04685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AH66_RS04690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AH66_RS04715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AH66_RS04715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AH66_RS04730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AH66_RS04735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AH66_RS04750	COG0142	geranyltranstransferase activity
AH66_RS04765	COG0693	protein deglycase activity
AH66_RS04770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AH66_RS04780	COG2814	Major facilitator Superfamily
AH66_RS04790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AH66_RS04795	COG1845	cytochrome c oxidase, subunit III
AH66_RS04800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AH66_RS04805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AH66_RS04815	COG2223	nitrite transmembrane transporter activity
AH66_RS04820	COG3056	Lipoprotein
AH66_RS04825	COG0271	Belongs to the BolA IbaG family
AH66_RS04845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AH66_RS04850	COG0776	regulation of translation
AH66_RS04855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AH66_RS04860	COG1555	photosystem II stabilization
AH66_RS04865	COG0824	Thioesterase
AH66_RS04875	COG4533	DNA binding
AH66_RS04890	COG1522	sequence-specific DNA binding
AH66_RS04895	COG1132	(ABC) transporter
AH66_RS04900	COG1132	(ABC) transporter
AH66_RS04905	COG0347	Belongs to the P(II) protein family
AH66_RS04910	COG0004	ammonium transporteR
AH66_RS04915	COG1946	Acyl-CoA thioesterase
AH66_RS04920	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AH66_RS04925	COG3695	enzyme binding
AH66_RS04950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AH66_RS04960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_RS04965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_RS04970	COG1309	transcriptional regulator
AH66_RS04975	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AH66_RS04980	COG1196	nuclear chromosome segregation
AH66_RS04980	COG3264	Mechanosensitive ion channel
AH66_RS05015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AH66_RS05045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_RS05045	COG0543	2 iron, 2 sulfur cluster binding
AH66_RS05065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_RS05125	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
AH66_RS05130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_RS05135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AH66_RS05135	COG4651	solute:proton antiporter activity
AH66_RS05140	COG2223	nitrite transmembrane transporter activity
AH66_RS05155	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AH66_RS05180	COG2217	Heavy metal translocating P-type atpase
AH66_RS05185	COG0789	Transcriptional regulator
AH66_RS05190	COG1585	Membrane protein implicated in regulation of membrane protease activity
AH66_RS05195	COG0330	HflC and HflK could
AH66_RS05200	COG3118	belongs to the thioredoxin family
AH66_RS05205	COG0300	oxidoreductase activity
AH66_RS05210	COG2755	lipolytic protein G-D-S-L family
AH66_RS05215	COG4181	ATPase activity
AH66_RS05220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AH66_RS05225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AH66_RS05230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AH66_RS05240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AH66_RS05260	COG1393	Belongs to the ArsC family
AH66_RS05265	COG4783	chaperone-mediated protein folding
AH66_RS05270	COG0628	permease
AH66_RS05280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AH66_RS05285	COG2716	regulation of RNA biosynthetic process
AH66_RS05295	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AH66_RS05310	COG2321	neutral zinc metallopeptidase
AH66_RS05330	COG1876	peptidase activity
AH66_RS05340	COG1393	Belongs to the ArsC family
AH66_RS05355	COG1175	transmembrane transport
AH66_RS05360	COG3842	ATPase activity
AH66_RS05370	COG3119	arylsulfatase activity
AH66_RS05375	COG0641	radical SAM
AH66_RS05380	COG1988	membrane-bound metal-dependent
AH66_RS05390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_RS05400	COG2197	response regulator
AH66_RS05405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_RS05405	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_RS05410	COG3062	negative regulation of establishment of protein localization
AH66_RS05420	COG3043	anaerobic respiration
AH66_RS05425	COG3005	denitrification pathway
AH66_RS05465	COG3111	PFAM Bacterial OB fold (BOF) protein
AH66_RS05475	COG2837	iron assimilation
AH66_RS05480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AH66_RS05500	COG2731	YhcH YjgK YiaL family protein
AH66_RS05505	COG1737	Transcriptional regulator
AH66_RS05515	COG4150	thiosulfate binding
AH66_RS05520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AH66_RS05525	COG4208	sulfate ABC transporter
AH66_RS05530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AH66_RS05545	COG0745	RESPONSE REGULATOR receiver
AH66_RS05550	COG3850	Histidine kinase
AH66_RS05550	COG5002	protein histidine kinase activity
AH66_RS05560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AH66_RS05580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AH66_RS05595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_RS05600	COG0745	RESPONSE REGULATOR receiver
AH66_RS05605	COG2205	protein histidine kinase activity
AH66_RS05625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS05635	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AH66_RS05650	COG3530	Putative quorum-sensing-regulated virulence factor
AH66_RS05715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AH66_RS05730	COG0667	Aldo Keto reductase
AH66_RS05755	COG0436	Aminotransferase
AH66_RS05760	COG3038	cytochrome b561
AH66_RS05790	COG3381	protein complex oligomerization
AH66_RS05795	COG3302	dmso reductase anchor subunit
AH66_RS05800	COG0437	4 iron, 4 sulfur cluster binding
AH66_RS05805	COG0243	molybdopterin cofactor binding
AH66_RS05840	COG2951	lytic endotransglycosylase activity
AH66_RS05900	COG3121	Chaperone
AH66_RS05905	COG3188	usher protein
AH66_RS05910	COG3328	transposase activity
AH66_RS05915	COG3188	usher protein
AH66_RS05990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS05995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS06000	COG1120	ATPase activity
AH66_RS06025	COG4160	amino acid transport
AH66_RS06030	COG4215	(ABC) transporter
AH66_RS06035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_RS06040	COG1126	abc transporter atp-binding protein
AH66_RS06045	COG1605	Chorismate mutase
AH66_RS06055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_RS06060	COG0702	epimerase
AH66_RS06065	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AH66_RS06075	COG0028	Belongs to the TPP enzyme family
AH66_RS06080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_RS06090	COG2431	L-lysine efflux transmembrane transporter activity
AH66_RS06095	COG3593	DNA synthesis involved in DNA repair
AH66_RS06100	COG2990	Protein conserved in bacteria
AH66_RS06105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_RS06115	COG1278	Cold shock
AH66_RS06125	COG0542	response to heat
AH66_RS06135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AH66_RS06145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AH66_RS06155	COG0492	ferredoxin-NADP+ reductase activity
AH66_RS06165	COG1674	ftsk spoiiie
AH66_RS06165	COG3107	peptidoglycan biosynthetic process
AH66_RS06175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AH66_RS06190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AH66_RS06200	COG1882	Formate acetyltransferase
AH66_RS06205	COG2116	formate transmembrane transporter activity
AH66_RS06210	COG1944	ATP diphosphatase activity
AH66_RS06215	COG0252	asparaginase activity
AH66_RS06220	COG5295	Hep Hag repeat protein
AH66_RS06220	COG5295	Hep Hag repeat protein
AH66_RS06245	COG0539	negative regulation of cytoplasmic translation
AH66_RS06255	COG2333	competence protein COMEC
AH66_RS06255	COG0658	competence protein
AH66_RS06270	COG5383	Protein conserved in bacteria
AH66_RS06275	COG1278	Cold shock
AH66_RS06290	COG3173	Aminoglycoside phosphotransferase
AH66_RS06295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AH66_RS06320	COG2989	Protein conserved in bacteria
AH66_RS06325	COG3108	Peptidase M15
AH66_RS06330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AH66_RS06340	COG1448	Aminotransferase
AH66_RS06360	COG0308	aminopeptidase N
AH66_RS06375	COG0633	Ferredoxin
AH66_RS06375	COG3217	Mosc domain protein beta barrel domain protein
AH66_RS06385	COG0488	(ABC) transporter
AH66_RS06390	COG2995	paraquat-inducible protein a
AH66_RS06395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AH66_RS06395	COG3008	intermembrane lipid transfer
AH66_RS06400	COG3009	Protein conserved in bacteria
AH66_RS06405	COG3130	regulation of translation
AH66_RS06445	COG1067	ATP-dependent peptidase activity
AH66_RS06470	COG3070	regulator of competence-specific genes
AH66_RS06475	COG1289	transmembrane transporter activity
AH66_RS06480	COG3304	Inner membrane component domain
AH66_RS06485	COG0210	DNA helicase
AH66_RS06500	COG1832	CoA-binding protein
AH66_RS06520	COG2920	part of a sulfur-relay system
AH66_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS06555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AH66_RS06560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AH66_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS06570	COG3425	synthase
AH66_RS06580	COG1024	Enoyl-CoA hydratase
AH66_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS06595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AH66_RS06600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AH66_RS06730	COG0488	(ABC) transporter
AH66_RS06740	COG3328	transposase activity
AH66_RS06750	COG0303	'Molybdopterin
AH66_RS06760	COG1136	(ABC) transporter
AH66_RS06790	COG0583	DNA-binding transcription factor activity
AH66_RS06795	COG0477	Major facilitator Superfamily
AH66_RS06805	COG2311	Membrane
AH66_RS06820	COG4211	Belongs to the binding-protein-dependent transport system permease family
AH66_RS06825	COG2949	membrane
AH66_RS06840	COG1346	cytolysis
AH66_RS06850	COG2814	Major facilitator Superfamily
AH66_RS06890	COG0489	protein tyrosine kinase activity
AH66_RS06905	COG2982	Protein involved in outer membrane biogenesis
AH66_RS06910	COG1253	flavin adenine dinucleotide binding
AH66_RS06915	COG4114	ferric iron reductase
AH66_RS06920	COG0076	glutamate decarboxylase activity
AH66_RS06925	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AH66_RS06940	COG1120	ATPase activity
AH66_RS06945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS06950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS06955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AH66_RS06970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AH66_RS06975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AH66_RS06985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AH66_RS06985	COG0140	phosphoribosyl-ATP diphosphatase activity
AH66_RS07005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AH66_RS07005	COG0131	Imidazoleglycerol-phosphate dehydratase
AH66_RS07015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AH66_RS07030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_RS07045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS07050	COG1129	ABC transporter
AH66_RS07055	COG1129	ABC transporter
AH66_RS07060	COG0371	Dehydrogenase
AH66_RS07065	COG0531	amino acid
AH66_RS07075	COG2925	Exonuclease
AH66_RS07090	COG3328	transposase activity
AH66_RS07095	COG1470	cell adhesion involved in biofilm formation
AH66_RS07095	COG1388	LysM domain
AH66_RS07100	COG2271	Major facilitator Superfamily
AH66_RS07105	COG3011	Protein conserved in bacteria
AH66_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS07120	COG4948	Mandelate Racemase Muconate Lactonizing
AH66_RS07135	COG0534	Mate efflux family protein
AH66_RS07155	COG3122	Protein conserved in bacteria
AH66_RS07180	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AH66_RS07200	COG2223	nitrite transmembrane transporter activity
AH66_RS07205	COG3328	transposase activity
AH66_RS07225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AH66_RS07235	COG3328	transposase activity
AH66_RS07240	COG1530	ribonuclease E activity
AH66_RS07245	COG0564	pseudouridine synthase activity
AH66_RS07255	COG0424	maF-like protein
AH66_RS07260	COG1399	metal-binding, possibly nucleic acid-binding protein
AH66_RS07265	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AH66_RS07295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AH66_RS07305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AH66_RS07310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AH66_RS07320	COG0470	DNA polymerase III
AH66_RS07325	COG0084	hydrolase, TatD family'
AH66_RS07330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_RS07330	COG1263	PTS System
AH66_RS07340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AH66_RS07345	COG0537	adenosine 5'-monophosphoramidase activity
AH66_RS07350	COG5633	Lipoprotein
AH66_RS07365	COG1472	Belongs to the glycosyl hydrolase 3 family
AH66_RS07375	COG1252	NADH dehydrogenase
AH66_RS07390	COG3328	transposase activity
AH66_RS07405	COG3134	Outer membrane lipoprotein
AH66_RS07410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AH66_RS07415	COG4591	ABC-type transport system involved in lipoprotein release permease component
AH66_RS07425	COG4591	ABC-type transport system involved in lipoprotein release permease component
AH66_RS07430	COG1940	carbohydrate kinase activity
AH66_RS07450	COG2850	peptidyl-arginine hydroxylation
AH66_RS07460	COG0745	RESPONSE REGULATOR receiver
AH66_RS07470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AH66_RS07490	COG1187	pseudouridine synthase activity
AH66_RS07495	COG0538	isocitrate dehydrogenase activity
AH66_RS07510	COG0840	transmembrane signaling receptor activity
AH66_RS07515	COG0702	epimerase
AH66_RS07520	COG1733	regulation of RNA biosynthetic process
AH66_RS07545	COG1522	sequence-specific DNA binding
AH66_RS07560	COG3321	synthase
AH66_RS07560	COG0604	alcohol dehydrogenase
AH66_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS07595	COG1285	pathogenesis
AH66_RS07620	COG1360	Flagellar Motor Protein
AH66_RS07625	COG0643	Histidine kinase
AH66_RS07625	COG2198	Histidine kinase
AH66_RS07630	COG0835	chemotaxis
AH66_RS07635	COG2271	Major facilitator Superfamily
AH66_RS07640	COG0251	oxidation-reduction process
AH66_RS07650	COG2964	Protein conserved in bacteria
AH66_RS07670	COG0840	transmembrane signaling receptor activity
AH66_RS07680	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AH66_RS07690	COG0745	RESPONSE REGULATOR receiver
AH66_RS07695	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AH66_RS07700	COG3023	N-Acetylmuramoyl-L-alanine amidase
AH66_RS07710	COG5295	Hep Hag repeat protein
AH66_RS07720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AH66_RS07775	COG3121	Chaperone
AH66_RS07800	COG2995	paraquat-inducible protein a
AH66_RS07805	COG1956	GAF domain-containing protein
AH66_RS07815	COG0793	Belongs to the peptidase S41A family
AH66_RS07825	COG3539	Fimbrial protein
AH66_RS07830	COG3121	Chaperone
AH66_RS07845	COG3121	Chaperone
AH66_RS07850	COG2814	Major facilitator Superfamily
AH66_RS07855	COG0823	Involved in the tonB-independent uptake of proteins
AH66_RS07865	COG3023	N-Acetylmuramoyl-L-alanine amidase
AH66_RS07870	COG1823	symporter activity
AH66_RS07875	COG1988	membrane-bound metal-dependent
AH66_RS07880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AH66_RS07885	COG1653	transport
AH66_RS07890	COG3842	ATPase activity
AH66_RS07895	COG0395	ABC-type sugar transport system, permease component
AH66_RS07900	COG1175	transmembrane transport
AH66_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS07920	COG1917	Cupin 2, conserved barrel domain protein
AH66_RS07925	COG3328	transposase activity
AH66_RS07970	COG1132	(ABC) transporter
AH66_RS07980	COG2207	Transcriptional regulator
AH66_RS08015	COG1113	amino acid transport
AH66_RS08035	COG1496	oxidoreductase activity
AH66_RS08040	COG2226	methyltransferase
AH66_RS08050	COG5002	protein histidine kinase activity
AH66_RS08050	COG3447	MASE1 domain protein
AH66_RS08050	COG5001	Diguanylate cyclase
AH66_RS08070	COG3716	PTS system mannose fructose sorbose family IID component
AH66_RS08075	COG3715	PTS system
AH66_RS08080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_RS08080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS08085	COG1253	flavin adenine dinucleotide binding
AH66_RS08090	COG1846	Transcriptional regulator
AH66_RS08105	COG1012	belongs to the aldehyde dehydrogenase family
AH66_RS08110	COG3384	dioxygenase
AH66_RS08120	COG3971	2-oxopent-4-enoate hydratase activity
AH66_RS08135	COG2368	4-hydroxyphenylacetate
AH66_RS08140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AH66_RS08145	COG1760	l-serine dehydratase
AH66_RS08170	COG0513	Belongs to the DEAD box helicase family
AH66_RS08175	COG3141	response to X-ray
AH66_RS08190	COG1770	oligopeptidase
AH66_RS08205	COG1528	Iron-storage protein
AH66_RS08210	COG2372	response to copper ion
AH66_RS08235	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AH66_RS08240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AH66_RS08265	COG3418	PFAM FlgN family protein
AH66_RS08270	COG2747	anti-sigma28 factor FlgM
AH66_RS08280	COG1815	bacterial-type flagellum-dependent cell motility
AH66_RS08285	COG1558	bacterial-type flagellum-dependent cell motility
AH66_RS08325	COG1256	bacterial-type flagellum assembly
AH66_RS08335	COG2390	Transcriptional regulator
AH66_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS08340	COG3347	Dehydrogenase
AH66_RS08345	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS08355	COG1129	ABC transporter
AH66_RS08360	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS08365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_RS08385	COG1987	bacterial-type flagellum assembly
AH66_RS08410	COG1580	Controls the rotational direction of flagella during chemotaxis
AH66_RS08425	COG1157	protein secretion by the type III secretion system
AH66_RS08445	COG1677	Flagellar hook-basal body complex protein FliE
AH66_RS08465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AH66_RS08470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AH66_RS08475	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AH66_RS08505	COG1191	sigma factor activity
AH66_RS08520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_RS08525	COG0765	amino acid transport
AH66_RS08530	COG1126	abc transporter atp-binding protein
AH66_RS08545	COG0506	proline dehydrogenase activity
AH66_RS08545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AH66_RS08545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AH66_RS08560	COG0672	)-iron permease
AH66_RS08565	COG2822	iron ion transport
AH66_RS08585	COG1113	amino acid transport
AH66_RS08605	COG3136	membrane protein required for alginate biosynthesis
AH66_RS08615	COG2197	response regulator
AH66_RS08740	COG2188	Transcriptional regulator
AH66_RS08745	COG0673	inositol 2-dehydrogenase activity
AH66_RS08755	COG1175	transmembrane transport
AH66_RS08760	COG0395	ABC-type sugar transport system, permease component
AH66_RS08765	COG3842	ATPase activity
AH66_RS08815	COG0402	S-adenosylhomocysteine deaminase activity
AH66_RS08830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AH66_RS08835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AH66_RS08840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_RS08885	COG3328	transposase activity
AH66_RS08905	COG0500	methyltransferase
AH66_RS08950	COG5002	protein histidine kinase activity
AH66_RS09000	COG0012	GTP binding
AH66_RS09015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AH66_RS09040	COG2890	protein-(glutamine-N5) methyltransferase activity
AH66_RS09065	COG0659	secondary active sulfate transmembrane transporter activity
AH66_RS09100	COG3833	ABC-type maltose transport systems, permease component
AH66_RS09105	COG1176	ABC-type spermidine putrescine transport system, permease component I
AH66_RS09125	COG0584	glycerophosphoryl diester phosphodiesterase
AH66_RS09130	COG1940	carbohydrate kinase activity
AH66_RS09145	COG3381	protein complex oligomerization
AH66_RS09160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AH66_RS09170	COG0728	peptidoglycan biosynthetic process
AH66_RS09190	COG3102	Protein conserved in bacteria
AH66_RS09210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AH66_RS09215	COG1801	Protein of unknown function DUF72
AH66_RS09225	COG0494	nUDIX hydrolase
AH66_RS09250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AH66_RS09260	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AH66_RS09265	COG0739	heme binding
AH66_RS09270	COG1560	Kdo2-lipid A biosynthetic process
AH66_RS09280	COG0469	pyruvate kinase activity
AH66_RS09285	COG1737	Transcriptional regulator
AH66_RS09290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AH66_RS09295	COG0800	Aldolase
AH66_RS09310	COG0251	oxidation-reduction process
AH66_RS09315	COG1199	ATP-dependent helicase activity
AH66_RS09325	COG3065	identical protein binding
AH66_RS09335	COG0318	PFAM AMP-dependent synthetase and ligase
AH66_RS09340	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AH66_RS09345	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AH66_RS09350	COG2894	cell division
AH66_RS09365	COG2951	lytic endotransglycosylase activity
AH66_RS09370	COG0179	Fumarylacetoacetate (FAA) hydrolase
AH66_RS09380	COG0582	viral genome integration into host DNA
AH66_RS09480	COG3328	transposase activity
AH66_RS09645	COG3328	transposase activity
AH66_RS09655	COG1104	cysteine desulfurase activity
AH66_RS09685	COG2719	SpoVR family
AH66_RS09695	COG2814	Major facilitator Superfamily
AH66_RS09705	COG0583	DNA-binding transcription factor activity
AH66_RS09720	COG2766	serine protein kinase
AH66_RS09725	COG3713	MltA-interacting MipA family protein
AH66_RS09745	COG3139	Protein of unknown function (DUF1315)
AH66_RS09750	COG1335	isochorismatase
AH66_RS09755	COG0252	asparaginase activity
AH66_RS09760	COG0616	signal peptide processing
AH66_RS09765	COG0778	Nitroreductase
AH66_RS09770	COG0709	Synthesizes selenophosphate from selenide and ATP
AH66_RS09775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AH66_RS09785	COG0494	nUDIX hydrolase
AH66_RS09790	COG0708	Exodeoxyribonuclease III
AH66_RS09795	COG0583	DNA-binding transcription factor activity
AH66_RS09815	COG3328	transposase activity
AH66_RS09820	COG0788	formyltetrahydrofolate deformylase activity
AH66_RS09830	COG0745	RESPONSE REGULATOR receiver
AH66_RS09860	COG1454	alcohol dehydrogenase
AH66_RS09860	COG1012	belongs to the aldehyde dehydrogenase family
AH66_RS09865	COG2095	MarC family integral membrane protein
AH66_RS09875	COG0601	transmembrane transport
AH66_RS09880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_RS09885	COG0444	Belongs to the ABC transporter superfamily
AH66_RS09890	COG4608	Belongs to the ABC transporter superfamily
AH66_RS09935	COG2350	Protein conserved in bacteria
AH66_RS09940	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AH66_RS09945	COG3328	transposase activity
AH66_RS09980	COG3047	cAMP biosynthetic process
AH66_RS10000	COG0135	phosphoribosylanthranilate isomerase activity
AH66_RS10000	COG0134	indole-3-glycerol-phosphate synthase activity
AH66_RS10010	COG0512	Glutamine amidotransferase of anthranilate synthase
AH66_RS10030	COG0009	L-threonylcarbamoyladenylate synthase
AH66_RS10035	COG1187	pseudouridine synthase activity
AH66_RS10045	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS10050	COG0616	signal peptide processing
AH66_RS10070	COG0583	DNA-binding transcription factor activity
AH66_RS10080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AH66_RS10090	COG0671	phosphoesterase, PA-phosphatase related
AH66_RS10095	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AH66_RS10100	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AH66_RS10115	COG0023	Translation Initiation Factor
AH66_RS10135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AH66_RS10140	COG2879	small protein
AH66_RS10145	COG1966	Carbon starvation protein
AH66_RS10155	COG2271	Major facilitator Superfamily
AH66_RS10160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AH66_RS10165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AH66_RS10175	COG4659	FMN binding
AH66_RS10180	COG4658	electron transport chain
AH66_RS10185	COG2207	Transcriptional regulator
AH66_RS10185	COG3708	Transcriptional regulator
AH66_RS10215	COG1132	(ABC) transporter
AH66_RS10225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_RS10230	COG2274	protein secretion by the type I secretion system
AH66_RS10245	COG1879	ABC-type sugar transport system periplasmic component
AH66_RS10250	COG1129	ABC transporter
AH66_RS10255	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS10265	COG0673	inositol 2-dehydrogenase activity
AH66_RS10270	COG0385	Bile acid
AH66_RS10305	COG0114	fumarate hydratase activity
AH66_RS10315	COG2814	Major facilitator Superfamily
AH66_RS10320	COG0583	DNA-binding transcription factor activity
AH66_RS10325	COG0583	DNA-binding transcription factor activity
AH66_RS10330	COG1940	carbohydrate kinase activity
AH66_RS10335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AH66_RS10340	COG0038	chloride channel
AH66_RS10390	COG4128	Pfam Zonular occludens toxin
AH66_RS10455	COG4128	Pfam Zonular occludens toxin
AH66_RS10475	COG1609	Transcriptional regulator
AH66_RS10495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AH66_RS10500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AH66_RS10530	COG0028	Belongs to the TPP enzyme family
AH66_RS10535	COG0440	acetolactate synthase activity
AH66_RS10540	COG1011	Hydrolase
AH66_RS10560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AH66_RS10565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AH66_RS10570	COG0589	response to stress
AH66_RS10575	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AH66_RS10580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AH66_RS10590	COG0531	amino acid
AH66_RS10600	COG0745	RESPONSE REGULATOR receiver
AH66_RS10605	COG2205	protein histidine kinase activity
AH66_RS10610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AH66_RS10635	COG3038	cytochrome b561
AH66_RS10645	COG3591	Belongs to the peptidase S1B family
AH66_RS10660	COG1643	Atp-dependent helicase
AH66_RS10670	COG2390	Transcriptional regulator
AH66_RS10675	COG0246	Mannitol dehydrogenase
AH66_RS10680	COG3784	Protein of unknown function (DUF1318)
AH66_RS10690	COG2911	Protein conserved in bacteria
AH66_RS10695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AH66_RS10700	COG3187	Heat shock protein
AH66_RS10705	COG3042	response to heat
AH66_RS10710	COG1285	pathogenesis
AH66_RS10720	COG1013	pyruvate-flavodoxin oxidoreductase activity
AH66_RS10720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AH66_RS10720	COG0674	pyruvate-flavodoxin oxidoreductase activity
AH66_RS10720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AH66_RS10730	COG0657	acetylesterase activity
AH66_RS10745	COG4166	transmembrane transport
AH66_RS10750	COG2866	Carboxypeptidase
AH66_RS10755	COG4948	Mandelate Racemase Muconate Lactonizing
AH66_RS10760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AH66_RS10775	COG5642	Protein of unknown function (DUF2384)
AH66_RS10780	COG5654	RES domain protein
AH66_RS10790	COG3106	COG3106 Predicted ATPase
AH66_RS10800	COG1983	PspC domain protein
AH66_RS10810	COG1842	Phage shock protein A
AH66_RS10815	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AH66_RS10825	COG4166	transmembrane transport
AH66_RS10830	COG4168	peptide transport system, permease
AH66_RS10835	COG4171	peptide transport system, permease
AH66_RS10845	COG4172	Belongs to the ABC transporter superfamily
AH66_RS10850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AH66_RS10850	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AH66_RS10855	COG3104	oligopeptide transport
AH66_RS10880	COG0625	glutathione transferase activity
AH66_RS10900	COG3895	Periplasmic Protein
AH66_RS10915	COG3313	Fe-S protein
AH66_RS10920	COG2194	sulfuric ester hydrolase activity
AH66_RS10925	COG1309	transcriptional regulator
AH66_RS10930	COG1902	pentaerythritol trinitrate reductase activity
AH66_RS10940	COG0346	lactoylglutathione lyase activity
AH66_RS10945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AH66_RS10955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AH66_RS10960	COG0791	NLP P60 protein
AH66_RS10980	COG0583	DNA-binding transcription factor activity
AH66_RS10985	COG2814	Major facilitator Superfamily
AH66_RS10990	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AH66_RS10995	COG0307	riboflavin synthase, alpha
AH66_RS11045	COG1388	LysM domain
AH66_RS11045	COG1376	ErfK ybiS ycfS ynhG family protein
AH66_RS11060	COG0719	Fe-S assembly protein
AH66_RS11065	COG0396	ATPase activity
AH66_RS11070	COG0719	Fe-S assembly protein
AH66_RS11075	COG0316	Belongs to the HesB IscA family
AH66_RS11080	COG2050	protein possibly involved in aromatic compounds catabolism
AH66_RS11085	COG0277	FAD linked oxidase domain protein
AH66_RS11085	COG0247	lactate metabolic process
AH66_RS11090	COG0628	permease
AH66_RS11100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AH66_RS11100	COG0574	Belongs to the PEP-utilizing enzyme family
AH66_RS11125	COG0791	NLP P60 protein
AH66_RS11175	COG0386	Belongs to the glutathione peroxidase family
AH66_RS11190	COG0776	regulation of translation
AH66_RS11195	COG0072	phenylalanine-tRNA ligase activity
AH66_RS11195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AH66_RS11230	COG4249	Peptidase C14 caspase catalytic subunit p20
AH66_RS11250	COG0803	Belongs to the bacterial solute-binding protein 9 family
AH66_RS11255	COG1121	(ABC) transporter
AH66_RS11260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AH66_RS11265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AH66_RS11275	COG3001	Fructosamine kinase
AH66_RS11285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_RS11290	COG3328	transposase activity
AH66_RS11310	COG0628	permease
AH66_RS11330	COG3916	Acyl-homoserine-lactone synthase
AH66_RS11335	COG2771	luxR family
AH66_RS11340	COG0583	DNA-binding transcription factor activity
AH66_RS11350	COG0477	Major facilitator Superfamily
AH66_RS11360	COG0667	Aldo Keto reductase
AH66_RS11385	COG1203	CRISPR-associated helicase, Cas3
AH66_RS11390	COG1518	maintenance of DNA repeat elements
AH66_RS11395	COG0668	transmembrane transport
AH66_RS11415	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AH66_RS11420	COG0395	ABC-type sugar transport system, permease component
AH66_RS11435	COG1609	Transcriptional regulator
AH66_RS11445	COG3842	ATPase activity
AH66_RS11455	COG3210	domain, Protein
AH66_RS11495	COG3210	domain, Protein
AH66_RS11500	COG2831	hemolysin activation secretion protein
AH66_RS11505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_RS11510	COG4638	Rieske (2fe-2S)
AH66_RS11515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AH66_RS11525	COG0473	3-isopropylmalate dehydrogenase activity
AH66_RS11530	COG0583	DNA-binding transcription factor activity
AH66_RS11535	COG1609	Transcriptional regulator
AH66_RS11540	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS11545	COG1129	ABC transporter
AH66_RS11550	COG1879	ABC-type sugar transport system periplasmic component
AH66_RS11555	COG1063	alcohol dehydrogenase
AH66_RS11575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AH66_RS11605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_RS11610	COG0765	amino acid transport
AH66_RS11615	COG1126	abc transporter atp-binding protein
AH66_RS11650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AH66_RS11665	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AH66_RS11680	COG1169	isochorismate synthase
AH66_RS11690	COG4575	ribosome binding
AH66_RS11695	COG0129	dihydroxy-acid dehydratase activity
AH66_RS11710	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AH66_RS11715	COG1609	Transcriptional regulator
AH66_RS11720	COG1649	PFAM Uncharacterised BCR, COG1649
AH66_RS11725	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS11730	COG3265	gluconokinase activity
AH66_RS11735	COG2731	YhcH YjgK YiaL family protein
AH66_RS11750	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AH66_RS11755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AH66_RS11765	COG0839	Belongs to the complex I subunit 6 family
AH66_RS11780	COG1034	ATP synthesis coupled electron transport
AH66_RS11810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AH66_RS11820	COG0583	DNA-binding transcription factor activity
AH66_RS11825	COG0436	Aminotransferase
AH66_RS11840	COG0471	metal ion transport
AH66_RS11840	COG0490	domain, Protein
AH66_RS11845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_RS11865	COG0280	phosphate acetyltransferase
AH66_RS11865	COG0857	belongs to the CobB CobQ family
AH66_RS11870	COG1609	Transcriptional regulator
AH66_RS11885	COG3328	transposase activity
AH66_RS11890	COG4953	penicillin-binding protein 1C
AH66_RS11895	COG2373	Large extracellular alpha-helical protein
AH66_RS11915	COG3962	Belongs to the TPP enzyme family
AH66_RS11930	COG1129	ABC transporter
AH66_RS11935	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS11940	COG0673	inositol 2-dehydrogenase activity
AH66_RS11945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_RS11955	COG3718	enzyme involved in inositol metabolism
AH66_RS11965	COG5265	(ABC) transporter
AH66_RS11990	COG2197	response regulator
AH66_RS12005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AH66_RS12010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AH66_RS12030	COG1686	Belongs to the peptidase S11 family
AH66_RS12035	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AH66_RS12040	COG0772	Belongs to the SEDS family
AH66_RS12045	COG0768	penicillin binding
AH66_RS12055	COG0799	negative regulation of ribosome biogenesis
AH66_RS12065	COG1466	dna polymerase III delta subunit
AH66_RS12080	COG2888	peptidyl-tyrosine sulfation
AH66_RS12085	COG1126	abc transporter atp-binding protein
AH66_RS12090	COG0765	amino acid transport
AH66_RS12095	COG0765	amino acid transport
AH66_RS12110	COG4535	Mg2 and Co2 transporter CorC
AH66_RS12120	COG1702	phosphate starvation-inducible protein PhoH
AH66_RS12125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AH66_RS12130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AH66_RS12160	COG0367	asparagine synthase
AH66_RS12165	COG0647	UMP catabolic process
AH66_RS12170	COG1940	carbohydrate kinase activity
AH66_RS12170	COG1846	Transcriptional regulator
AH66_RS12175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AH66_RS12185	COG1263	PTS System
AH66_RS12185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_RS12185	COG2190	(PTS) system
AH66_RS12210	COG0735	belongs to the Fur family
AH66_RS12225	COG0596	Alpha beta hydrolase
AH66_RS12235	COG0582	viral genome integration into host DNA
AH66_RS12270	COG2113	Glycine betaine
AH66_RS12275	COG4176	ABC-type proline glycine betaine transport system permease component
AH66_RS12280	COG4175	Glycine betaine
AH66_RS12285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AH66_RS12320	COG3328	transposase activity
AH66_RS12330	COG1278	Cold shock
AH66_RS12335	COG0747	negative chemotaxis
AH66_RS12345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AH66_RS12350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AH66_RS12355	COG1124	(ABC) transporter
AH66_RS12360	COG0831	urea catabolic process
AH66_RS12385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AH66_RS12395	COG4413	Urea transporter
AH66_RS12400	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AH66_RS12410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AH66_RS12420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AH66_RS12430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AH66_RS12435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AH66_RS12440	COG1447	Phosphotransferase system cellobiose-specific component IIA
AH66_RS12445	COG1917	Cupin 2, conserved barrel domain protein
AH66_RS12445	COG2169	Transcriptional regulator
AH66_RS12460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AH66_RS12465	COG0033	Phosphoglucomutase
AH66_RS12480	COG0745	RESPONSE REGULATOR receiver
AH66_RS12485	COG2205	protein histidine kinase activity
AH66_RS12520	COG3272	Protein of unknown function (DUF1722)
AH66_RS12530	COG5212	phosphodiesterase
AH66_RS12535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AH66_RS12550	COG1984	allophanate hydrolase subunit 2
AH66_RS12595	COG0513	Belongs to the DEAD box helicase family
AH66_RS12605	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AH66_RS12620	COG3026	antisigma factor binding
AH66_RS12625	COG3086	response to oxidative stress
AH66_RS12710	COG2824	Alkylphosphonate utilization operon protein PhnA
AH66_RS12720	COG1704	LemA family
AH66_RS12740	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AH66_RS12745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AH66_RS12750	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AH66_RS12760	COG1138	Cytochrome C-type biogenesis protein
AH66_RS12765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AH66_RS12770	COG3088	subunit of a heme lyase
AH66_RS12770	COG4235	cytochrome complex assembly
AH66_RS12775	COG4235	cytochrome complex assembly
AH66_RS12775	COG3088	subunit of a heme lyase
AH66_RS12790	COG3691	Protein conserved in bacteria
AH66_RS12805	COG2062	phosphohistidine phosphatase, SixA
AH66_RS12815	COG2890	protein-(glutamine-N5) methyltransferase activity
AH66_RS12825	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AH66_RS12830	COG0730	response to heat
AH66_RS12835	COG3101	peptidyl-lysine hydroxylation
AH66_RS12850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AH66_RS12855	COG1794	racemase activity, acting on amino acids and derivatives
AH66_RS12870	COG0697	spore germination
AH66_RS12890	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AH66_RS12900	COG0586	Pfam SNARE associated Golgi protein
AH66_RS12910	COG0285	dihydrofolate synthase activity
AH66_RS12915	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AH66_RS12920	COG1286	toxin biosynthetic process
AH66_RS12925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AH66_RS12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_RS12940	COG4215	(ABC) transporter
AH66_RS12945	COG4160	amino acid transport
AH66_RS12950	COG4598	ABC transporter
AH66_RS12955	COG1090	epimerase
AH66_RS12970	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AH66_RS12975	COG3037	sugar-specific permease SgaT UlaA
AH66_RS12980	COG3328	transposase activity
AH66_RS12985	COG4953	penicillin-binding protein 1C
AH66_RS12990	COG3423	Transcriptional regulator
AH66_RS13045	COG3328	transposase activity
AH66_RS13060	COG1472	Belongs to the glycosyl hydrolase 3 family
AH66_RS13070	COG0656	L-ascorbic acid biosynthetic process
AH66_RS13075	COG0667	Aldo Keto reductase
AH66_RS13105	COG2453	phosphatase
AH66_RS13105	COG0671	phosphoesterase, PA-phosphatase related
AH66_RS13110	COG2267	carboxylic ester hydrolase activity
AH66_RS13120	COG4589	Belongs to the CDS family
AH66_RS13125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AH66_RS13135	COG0582	viral genome integration into host DNA
AH66_RS13170	COG2501	S4 domain
AH66_RS13190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AH66_RS13195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AH66_RS13210	COG0581	inorganic phosphate transmembrane transporter activity
AH66_RS13220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AH66_RS13235	COG2239	Acts as a magnesium transporter
AH66_RS13240	COG0443	Heat shock 70 kDa protein
AH66_RS13245	COG1177	transmembrane transport
AH66_RS13250	COG1176	ABC-type spermidine putrescine transport system, permease component I
AH66_RS13260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AH66_RS13270	COG3842	ATPase activity
AH66_RS13300	COG0745	RESPONSE REGULATOR receiver
AH66_RS13305	COG3422	double-strand break repair
AH66_RS13310	COG0826	peptidase U32
AH66_RS13335	COG0351	phosphomethylpyrimidine kinase
AH66_RS13350	COG3328	transposase activity
AH66_RS13395	COG0517	IMP dehydrogenase activity
AH66_RS13395	COG0516	GMP reductase activity
AH66_RS13405	COG1645	bacterial-type flagellum-dependent swarming motility
AH66_RS13420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH66_RS13425	COG2976	Protein conserved in bacteria
AH66_RS13465	COG3468	outer membrane autotransporter barrel domain protein
AH66_RS13470	COG3468	outer membrane autotransporter barrel domain protein
AH66_RS13495	COG2975	iron-sulfur cluster assembly
AH66_RS13500	COG0633	Ferredoxin
AH66_RS13505	COG0443	Heat shock 70 kDa protein
AH66_RS13520	COG0822	iron-sulfur transferase activity
AH66_RS13525	COG1104	cysteine desulfurase activity
AH66_RS13550	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AH66_RS13555	COG3683	transport system, periplasmic component
AH66_RS13560	COG3711	transcriptional antiterminator
AH66_RS13565	COG2814	Major facilitator Superfamily
AH66_RS13585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_RS13585	COG1017	nitric oxide dioxygenase activity
AH66_RS13595	COG0347	Belongs to the P(II) protein family
AH66_RS13600	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AH66_RS13600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AH66_RS13605	COG2204	response regulator
AH66_RS13610	COG3170	Tfp pilus assembly protein FimV
AH66_RS13615	COG2205	protein histidine kinase activity
AH66_RS13660	COG0560	Phosphoserine phosphatase
AH66_RS13670	COG1737	Transcriptional regulator
AH66_RS13675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_RS13690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AH66_RS13720	COG1177	transmembrane transport
AH66_RS13725	COG1176	ABC-type spermidine putrescine transport system, permease component I
AH66_RS13730	COG3842	ATPase activity
AH66_RS13735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AH66_RS13765	COG0671	phosphoesterase, PA-phosphatase related
AH66_RS13775	COG1349	DNA-binding transcription factor activity
AH66_RS13780	COG0814	amino acid
AH66_RS13785	COG1686	Belongs to the peptidase S11 family
AH66_RS13790	COG2011	ABC-type metal ion transport system permease component
AH66_RS13815	COG0625	glutathione transferase activity
AH66_RS13820	COG4771	TonB-dependent receptor
AH66_RS13830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS13840	COG0833	amino acid
AH66_RS13845	COG0583	DNA-binding transcription factor activity
AH66_RS13850	COG2855	membrane
AH66_RS13860	COG3188	usher protein
AH66_RS13865	COG3121	Chaperone
AH66_RS13880	COG3710	Transcriptional regulator
AH66_RS13885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_RS13885	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AH66_RS13885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_RS13890	COG1105	Belongs to the carbohydrate kinase PfkB family
AH66_RS13900	COG0494	nUDIX hydrolase
AH66_RS13910	COG1129	ABC transporter
AH66_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS13970	COG0246	Mannitol dehydrogenase
AH66_RS13975	COG2186	Transcriptional regulator
AH66_RS13980	COG0523	cobalamin synthesis protein
AH66_RS13985	COG0671	phosphoesterase, PA-phosphatase related
AH66_RS13990	COG0791	NLP P60 protein
AH66_RS13995	COG2200	EAL domain
AH66_RS14000	COG4166	transmembrane transport
AH66_RS14005	COG4174	ABC transporter (Permease)
AH66_RS14010	COG4239	(ABC) transporter, permease
AH66_RS14015	COG4172	Belongs to the ABC transporter superfamily
AH66_RS14025	COG2814	Major facilitator Superfamily
AH66_RS14030	COG1187	pseudouridine synthase activity
AH66_RS14035	COG1061	Type III restriction enzyme res subunit
AH66_RS14055	COG3082	Protein of unknown function (DUF1414)
AH66_RS14060	COG3083	sulfuric ester hydrolase activity
AH66_RS14075	COG3157	Type VI secretion system effector, Hcp
AH66_RS14095	COG2723	6-phospho-beta-galactosidase activity
AH66_RS14100	COG1737	Transcriptional regulator
AH66_RS14120	COG3299	homolog of phage Mu protein gp47
AH66_RS14160	COG4386	tail sheath protein
AH66_RS14180	COG3622	Belongs to the hyi family
AH66_RS14185	COG1349	DNA-binding transcription factor activity
AH66_RS14195	COG3395	kinase activity
AH66_RS14235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AH66_RS14265	COG2223	nitrite transmembrane transporter activity
AH66_RS14270	COG2198	Histidine kinase
AH66_RS14270	COG0642	Histidine kinase
AH66_RS14275	COG0642	Histidine kinase
AH66_RS14275	COG2198	Histidine kinase
AH66_RS14285	COG0784	Response regulator, receiver
AH66_RS14285	COG2205	protein histidine kinase activity
AH66_RS14310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AH66_RS14325	COG0814	amino acid
AH66_RS14350	COG0697	spore germination
AH66_RS14360	COG1982	Orn Lys Arg decarboxylase major
AH66_RS14365	COG0531	amino acid
AH66_RS14370	COG1174	glycine betaine transport
AH66_RS14375	COG1125	glycine betaine transport
AH66_RS14380	COG1174	glycine betaine transport
AH66_RS14390	COG2897	thiosulfate sulfurtransferase activity
AH66_RS14410	COG1122	ATPase activity
AH66_RS14430	COG4807	Protein conserved in bacteria
AH66_RS14445	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AH66_RS14455	COG2261	transglycosylase associated protein
AH66_RS14475	COG0277	FAD linked oxidase domain protein
AH66_RS14480	COG1686	Belongs to the peptidase S11 family
AH66_RS14490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AH66_RS14505	COG0670	Belongs to the BI1 family
AH66_RS14510	COG0314	molybdopterin synthase activity
AH66_RS14515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AH66_RS14525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AH66_RS14530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AH66_RS14535	COG4628	conserved protein (DUF2132)
AH66_RS14545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AH66_RS14555	COG2226	methyltransferase
AH66_RS14580	COG0561	phosphatase activity
AH66_RS14590	COG4149	molybdate abc transporter
AH66_RS14595	COG0725	ABC transporter, periplasmic molybdate-binding protein
AH66_RS14605	COG3585	molybdate ion transport
AH66_RS14605	COG2005	Transcriptional regulator
AH66_RS14610	COG1119	ATPase activity
AH66_RS14620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AH66_RS14625	COG1085	galactose-1-phosphate uridylyltransferase
AH66_RS14640	COG2017	converts alpha-aldose to the beta-anomer
AH66_RS14655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AH66_RS14670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AH66_RS14675	COG1230	cation diffusion facilitator family transporter
AH66_RS14705	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AH66_RS14710	COG2885	chlorophyll binding
AH66_RS14720	COG3064	Membrane
AH66_RS14720	COG3064	Membrane
AH66_RS14725	COG0848	biopolymer transport protein
AH66_RS14730	COG0811	peptide transport
AH66_RS14735	COG0824	Thioesterase
AH66_RS14740	COG3790	cyd operon protein YbgE
AH66_RS14745	COG4890	Cyd operon protein YbgT
AH66_RS14750	COG1294	oxidase, subunit
AH66_RS14755	COG1271	oxidase subunit
AH66_RS14760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AH66_RS14770	COG0508	dehydrogenase complex catalyzes the overall conversion of
AH66_RS14775	COG0567	Dehydrogenase, E1 component
AH66_RS14785	COG1053	succinate dehydrogenase
AH66_RS14790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AH66_RS14795	COG2009	succinate dehydrogenase
AH66_RS14810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AH66_RS14815	COG0497	DNA recombination
AH66_RS14820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AH66_RS14830	COG2867	negative regulation of translational initiation
AH66_RS14850	COG0582	viral genome integration into host DNA
AH66_RS14900	COG3657	addiction module killer protein
AH66_RS14925	COG1953	Uracil, thiamine, allantoin
AH66_RS14945	COG2226	methyltransferase
AH66_RS14950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AH66_RS14955	COG1388	LysM domain
AH66_RS14955	COG0741	lytic transglycosylase activity
AH66_RS14970	COG0656	L-ascorbic acid biosynthetic process
AH66_RS15005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AH66_RS15015	COG2011	ABC-type metal ion transport system permease component
AH66_RS15020	COG1464	Belongs to the NlpA lipoprotein family
AH66_RS15030	COG1720	tRNA m6t6A37 methyltransferase activity
AH66_RS15040	COG3015	lipoprotein NlpE involved in copper resistance
AH66_RS15050	COG4681	YaeQ
AH66_RS15060	COG4568	rho-dependent transcription termination
AH66_RS15070	COG0037	tRNA processing
AH66_RS15075	COG0346	lactoylglutathione lyase activity
AH66_RS15085	COG0587	DNA-directed DNA polymerase activity
AH66_RS15110	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AH66_RS15125	COG0750	zinc metalloprotease
AH66_RS15130	COG0575	Belongs to the CDS family
AH66_RS15190	COG0564	pseudouridine synthase activity
AH66_RS15195	COG3098	single-species biofilm formation
AH66_RS15215	COG1611	Belongs to the LOG family
AH66_RS15230	COG2363	Small membrane protein
AH66_RS15235	COG0583	DNA-binding transcription factor activity
AH66_RS15245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AH66_RS15250	COG2166	iron-sulfur cluster assembly
AH66_RS15255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AH66_RS15260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AH66_RS15275	COG0860	N-Acetylmuramoyl-L-alanine amidase
AH66_RS15285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AH66_RS15290	COG1074	ATP-dependent DNA helicase activity
AH66_RS15300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AH66_RS15340	COG4771	TonB-dependent receptor
AH66_RS15345	COG2195	Cleaves the N-terminal amino acid of tripeptides
AH66_RS15350	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AH66_RS15395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_RS15405	COG5001	Diguanylate cyclase
AH66_RS15415	COG2211	Major facilitator Superfamily
AH66_RS15465	COG2771	luxR family
AH66_RS15470	COG3916	Acyl-homoserine-lactone synthase
AH66_RS15590	COG1982	Orn Lys Arg decarboxylase major
AH66_RS15595	COG1879	ABC-type sugar transport system periplasmic component
AH66_RS15600	COG1129	ABC transporter
AH66_RS15605	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS15610	COG4774	siderophore transport
AH66_RS15630	COG1194	a g-specific adenine glycosylase
AH66_RS15640	COG3171	Protein conserved in bacteria
AH66_RS15655	COG1073	alpha beta
AH66_RS15655	COG3064	Membrane
AH66_RS15655	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AH66_RS15660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AH66_RS15665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AH66_RS15675	COG0762	integral membrane protein
AH66_RS15680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AH66_RS15685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AH66_RS15690	COG2805	Type II/IV secretion system protein
AH66_RS15700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AH66_RS15715	COG0189	ligase activity
AH66_RS15720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AH66_RS15725	COG2356	endonuclease I
AH66_RS15730	COG3091	SprT-like family
AH66_RS15740	COG1166	arginine decarboxylase activity
AH66_RS15765	COG0501	Belongs to the peptidase M48B family
AH66_RS15770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AH66_RS15790	COG0191	fructose-bisphosphate aldolase activity
AH66_RS15825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AH66_RS15835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AH66_RS15855	COG0006	proline dipeptidase activity
AH66_RS15860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AH66_RS15865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AH66_RS15910	COG1272	protein, Hemolysin III
AH66_RS15935	COG0745	RESPONSE REGULATOR receiver
AH66_RS15940	COG2205	protein histidine kinase activity
AH66_RS15945	COG4452	Inner membrane protein CreD
AH66_RS15950	COG0716	FMN binding
AH66_RS15955	COG4974	Belongs to the 'phage' integrase family
AH66_RS15960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AH66_RS15965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AH66_RS15985	COG0582	viral genome integration into host DNA
AH66_RS16010	COG2944	sequence-specific DNA binding
AH66_RS16100	COG1695	Transcriptional regulator
AH66_RS16105	COG0791	NLP P60 protein
AH66_RS16115	COG1879	ABC-type sugar transport system periplasmic component
AH66_RS16120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AH66_RS16125	COG1129	ABC transporter
AH66_RS16135	COG2182	Extracellular solute-binding protein
AH66_RS16140	COG1175	transmembrane transport
AH66_RS16145	COG3833	ABC-type maltose transport systems, permease component
AH66_RS16150	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AH66_RS16155	COG1874	Beta-galactosidase
AH66_RS16160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_RS16160	COG1263	PTS System
AH66_RS16180	COG2271	Major facilitator Superfamily
AH66_RS16205	COG3119	arylsulfatase activity
AH66_RS16210	COG0641	radical SAM
AH66_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
AH66_RS16230	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS16235	COG3716	PTS system mannose fructose sorbose family IID component
AH66_RS16240	COG3715	PTS system
AH66_RS16245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AH66_RS16250	COG2222	sugar isomerase
AH66_RS16260	COG1349	DNA-binding transcription factor activity
AH66_RS16265	COG3119	arylsulfatase activity
AH66_RS16305	COG0288	reversible hydration of carbon dioxide
AH66_RS16325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AH66_RS16345	COG2165	general secretion pathway protein
AH66_RS16385	COG0840	transmembrane signaling receptor activity
AH66_RS16400	COG0583	DNA-binding transcription factor activity
AH66_RS16405	COG2814	Major facilitator Superfamily
AH66_RS16410	COG0583	DNA-binding transcription factor activity
AH66_RS16420	COG1609	Transcriptional regulator
AH66_RS16450	COG0667	Aldo Keto reductase
AH66_RS16495	COG2226	methyltransferase
AH66_RS16495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AH66_RS16495	COG3433	isochorismatase activity
AH66_RS16505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AH66_RS16505	COG3433	isochorismatase activity
AH66_RS16505	COG2226	methyltransferase
AH66_RS16530	COG1132	(ABC) transporter
AH66_RS16530	COG2375	cellular response to nickel ion
AH66_RS16535	COG1132	(ABC) transporter
AH66_RS16550	COG2610	gluconate transmembrane transporter activity
AH66_RS16565	COG3501	Rhs element vgr protein
AH66_RS16575	COG3209	COG3209 Rhs family protein
AH66_RS16590	COG0471	metal ion transport
AH66_RS16640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AH66_RS16645	COG1191	sigma factor activity
AH66_RS16670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AH66_RS16690	COG3710	Transcriptional regulator
AH66_RS16710	COG1256	bacterial-type flagellum assembly
AH66_RS16720	COG1706	bacterial-type flagellum-dependent cell motility
AH66_RS16730	COG4786	Flagellar basal body rod
AH66_RS16750	COG1749	Flagellar hook protein flgE
AH66_RS16755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AH66_RS16760	COG1558	bacterial-type flagellum-dependent cell motility
AH66_RS16765	COG1815	bacterial-type flagellum-dependent cell motility
AH66_RS16770	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AH66_RS16810	COG1677	Flagellar hook-basal body complex protein FliE
AH66_RS16835	COG1987	bacterial-type flagellum assembly
AH66_RS16840	COG1684	flagellar biosynthetic protein fliR
AH66_RS16845	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AH66_RS16865	COG4592	Periplasmic binding protein
AH66_RS16905	COG4964	Belongs to the GSP D family
AH66_RS16910	COG4964	Belongs to the GSP D family
AH66_RS16960	COG0848	biopolymer transport protein
AH66_RS16965	COG0811	peptide transport
AH66_RS16970	COG0626	cystathionine gamma-synthase activity
AH66_RS16975	COG0586	Pfam SNARE associated Golgi protein
AH66_RS16980	COG2207	Transcriptional regulator
AH66_RS16985	COG1979	alcohol dehydrogenase
AH66_RS16995	COG0656	L-ascorbic acid biosynthetic process
AH66_RS17005	COG2132	Multicopper oxidase
AH66_RS17015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AH66_RS17025	COG2249	NAD(P)H dehydrogenase (quinone) activity
AH66_RS17030	COG0583	DNA-binding transcription factor activity
AH66_RS17040	COG3150	esterase
AH66_RS17045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AH66_RS17050	COG3151	Protein conserved in bacteria
AH66_RS17055	COG0494	nUDIX hydrolase
AH66_RS17060	COG1538	Outer membrane efflux protein
AH66_RS17070	COG0754	glutathionylspermidine amidase activity
AH66_RS17075	COG3384	dioxygenase
AH66_RS17095	COG0531	amino acid
AH66_RS17110	COG3025	triphosphatase activity
AH66_RS17115	COG4991	sh3 domain protein
AH66_RS17130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AH66_RS17145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AH66_RS17150	COG0358	DNA primase activity
AH66_RS17220	COG0251	oxidation-reduction process
AH66_RS17245	COG1289	transmembrane transporter activity
AH66_RS17265	COG0395	ABC-type sugar transport system, permease component
AH66_RS17275	COG2182	Extracellular solute-binding protein
AH66_RS17280	COG1609	Transcriptional regulator
AH66_RS17285	COG3459	Glycosyltransferase 36 associated
AH66_RS17290	COG3842	ATPase activity
AH66_RS17310	COG3210	domain, Protein
AH66_RS17315	COG3210	domain, Protein
AH66_RS17345	COG3210	domain, Protein
AH66_RS17350	COG3210	domain, Protein
AH66_RS17355	COG2831	hemolysin activation secretion protein
AH66_RS17360	COG4245	von Willebrand factor, type A
AH66_RS17375	COG4245	von Willebrand factor, type A
AH66_RS17390	COG3247	response to pH
AH66_RS17395	COG1902	pentaerythritol trinitrate reductase activity
AH66_RS17395	COG0446	pyridine nucleotide-disulphide oxidoreductase
AH66_RS17410	COG1451	nucleotide metabolic process
AH66_RS17415	COG0673	inositol 2-dehydrogenase activity
AH66_RS17435	COG2721	sulfolactate sulfo-lyase activity
AH66_RS17450	COG2271	Major facilitator Superfamily
AH66_RS17465	COG0586	Pfam SNARE associated Golgi protein
AH66_RS17480	COG4575	ribosome binding
AH66_RS17485	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
AH66_RS17495	COG2259	Doxx family
AH66_RS17515	COG0494	nUDIX hydrolase
AH66_RS17545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AH66_RS17550	COG0849	cell division
AH66_RS17555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AH66_RS17575	COG0772	Belongs to the SEDS family
AH66_RS17590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AH66_RS17595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AH66_RS17600	COG0768	penicillin binding
AH66_RS17605	COG3116	cell division
AH66_RS17630	COG1609	Transcriptional regulator
AH66_RS17645	COG0028	Belongs to the TPP enzyme family
AH66_RS17650	COG1022	Amp-dependent synthetase and ligase
AH66_RS17675	COG0473	3-isopropylmalate dehydrogenase activity
AH66_RS17690	COG2814	Major facilitator Superfamily
AH66_RS17715	COG4143	(ABC) transporter
AH66_RS17720	COG1178	ABC-type Fe3 transport system permease component
AH66_RS17725	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AH66_RS17730	COG0586	Pfam SNARE associated Golgi protein
AH66_RS17735	COG0417	DNA replication proofreading
AH66_RS17755	COG2885	chlorophyll binding
AH66_RS17755	COG3047	cAMP biosynthetic process
AH66_RS17840	COG0564	pseudouridine synthase activity
AH66_RS17845	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AH66_RS17895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AH66_RS17905	COG2966	Psort location CytoplasmicMembrane, score
AH66_RS17910	COG1280	lysine exporter protein (LysE YggA)
AH66_RS17915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AH66_RS17940	COG1047	Peptidyl-prolyl cis-trans
AH66_RS17955	COG0196	riboflavin kinase activity
AH66_RS17965	COG0583	DNA-binding transcription factor activity
AH66_RS17985	COG1584	GPR1 FUN34 yaaH family protein
AH66_RS18000	COG0521	Mo-molybdopterin cofactor biosynthetic process
AH66_RS18040	COG0745	RESPONSE REGULATOR receiver
AH66_RS18045	COG3045	CreA protein
AH66_RS18050	COG2207	Transcriptional regulator
AH66_RS18050	COG3708	Transcriptional regulator
AH66_RS18065	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AH66_RS18070	COG0741	lytic transglycosylase activity
AH66_RS18085	COG2199	diguanylate cyclase activity
AH66_RS18090	COG2885	chlorophyll binding
AH66_RS18115	COG0560	Phosphoserine phosphatase
AH66_RS18120	COG3726	membrane protein affecting hemolysin expression
AH66_RS18145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AH66_RS18150	COG0084	hydrolase, TatD family'
AH66_RS18155	COG4667	esterase of the alpha-beta hydrolase superfamily
AH66_RS18165	COG2823	Periplasmic or secreted lipoprotein
AH66_RS18175	COG0456	acetyltransferase
AH66_RS18180	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
AH66_RS18220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AH66_RS18225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AH66_RS18240	COG0859	PFAM glycosyl transferase family 9
AH66_RS18245	COG1070	Carbohydrate kinase
AH66_RS18295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AH66_RS18295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS18295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AH66_RS18300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_RS18305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_RS18310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AH66_RS18315	COG2207	Transcriptional regulator
AH66_RS18325	COG4269	membrane
AH66_RS18380	COG1401	restriction endodeoxyribonuclease activity
AH66_RS18400	COG3650	response to hydrogen peroxide
AH66_RS18405	COG1960	acyl-CoA dehydrogenase activity
AH66_RS18410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AH66_RS18415	COG0557	exoribonuclease II activity
AH66_RS18430	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AH66_RS18435	COG0330	HflC and HflK could
AH66_RS18440	COG0330	HflC and HflK could
AH66_RS18445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AH66_RS18465	COG0860	N-Acetylmuramoyl-L-alanine amidase
AH66_RS18470	COG0802	atpase or kinase
AH66_RS18475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AH66_RS18475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AH66_RS18480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AH66_RS18490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AH66_RS18505	COG1511	domain protein
AH66_RS18505	COG3264	Mechanosensitive ion channel
AH66_RS18520	COG1053	succinate dehydrogenase
AH66_RS18525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AH66_RS18535	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AH66_RS18600	COG3383	formate dehydrogenase (NAD+) activity
AH66_RS18605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_RS18610	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AH66_RS18610	COG0493	'glutamate synthase
AH66_RS18615	COG1309	transcriptional regulator
AH66_RS18675	COG1454	alcohol dehydrogenase
AH66_RS18685	COG0629	single-stranded DNA binding
AH66_RS18690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AH66_RS18695	COG2315	Protein conserved in bacteria
AH66_RS18700	COG1448	Aminotransferase
AH66_RS18725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AH66_RS18730	COG0735	belongs to the Fur family
AH66_RS18740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AH66_RS18780	COG3121	Chaperone
AH66_RS18840	COG1358	cellular component organization or biogenesis
AH66_RS18865	COG3721	Heme iron utilization protein
AH66_RS18870	COG0702	epimerase
AH66_RS18880	COG4771	TonB-dependent receptor
AH66_RS18885	COG3720	iron ion transport
AH66_RS18890	COG4558	Periplasmic binding protein
AH66_RS18895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AH66_RS18905	COG0626	cystathionine gamma-synthase activity
AH66_RS18910	COG0814	amino acid
AH66_RS18915	COG0583	DNA-binding transcription factor activity
AH66_RS18920	COG0425	Belongs to the sulfur carrier protein TusA family
AH66_RS18925	COG2391	methyltransferase activity
AH66_RS19035	COG1301	dicarboxylic acid transport
AH66_RS19045	COG3162	membrane
AH66_RS19070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AH66_RS19085	COG0551	DNA topoisomerase type I activity
AH66_RS19095	COG0758	DNA mediated transformation
AH66_RS19125	COG3036	rescue of stalled ribosome
AH66_RS19130	COG0789	Transcriptional regulator
AH66_RS19145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AH66_RS19160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AH66_RS19165	COG0201	protein transport
AH66_RS19175	COG1841	ribosomal large subunit assembly
AH66_RS19215	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AH66_RS19220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AH66_RS19230	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AH66_RS19235	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AH66_RS19245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AH66_RS19255	COG0089	rRNA binding
AH66_RS19270	COG0051	transcription antitermination factor activity, RNA binding
AH66_RS19300	COG0049	tRNA binding
AH66_RS19305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AH66_RS19325	COG2964	Protein conserved in bacteria
AH66_RS19330	COG0545	Peptidyl-prolyl cis-trans isomerase
AH66_RS19340	COG1047	Peptidyl-prolyl cis-trans
AH66_RS19345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AH66_RS19365	COG1216	Glycosyl transferase, family 2
AH66_RS19375	COG2175	clavaminate synthase activity
AH66_RS19380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AH66_RS19390	COG4521	taurine ABC transporter
AH66_RS19400	COG0429	hydrolase of the alpha beta-hydrolase fold
AH66_RS19410	COG3954	Phosphoribulokinase
AH66_RS19420	COG1765	OsmC-like protein
AH66_RS19430	COG1289	transmembrane transporter activity
AH66_RS19465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AH66_RS19470	COG1486	melibiose metabolic process
AH66_RS19490	COG0402	S-adenosylhomocysteine deaminase activity
AH66_RS19495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AH66_RS19515	COG0180	Tryptophanyl-tRNA synthetase
AH66_RS19520	COG0546	phosphoglycolate phosphatase activity
AH66_RS19525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AH66_RS19550	COG4796	Type ii and iii secretion system protein
AH66_RS19575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AH66_RS19580	COG0494	nUDIX hydrolase
AH66_RS19590	COG1011	Hydrolase
AH66_RS19595	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AH66_RS19620	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AH66_RS19625	COG2183	response to ionizing radiation
AH66_RS19630	COG1918	ferrous iron import across plasma membrane
AH66_RS19665	COG1640	4-alpha-glucanotransferase
AH66_RS19670	COG0058	SHG alpha-glucan phosphorylase activity
AH66_RS19675	COG0058	SHG alpha-glucan phosphorylase activity
AH66_RS19685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AH66_RS19695	COG1349	DNA-binding transcription factor activity
AH66_RS19710	COG0460	homoserine dehydrogenase
AH66_RS19710	COG0527	aspartate kinase activity
AH66_RS19725	COG4682	membrane
AH66_RS19735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AH66_RS19740	COG1609	Transcriptional regulator
AH66_RS19745	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AH66_RS19760	COG1575	Belongs to the MenA family. Type 1 subfamily
AH66_RS19815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AH66_RS19825	COG1494	fructose-1,6-bisphosphatase
AH66_RS19835	COG3152	Membrane
AH66_RS19850	COG0583	DNA-binding transcription factor activity
AH66_RS19855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AH66_RS19860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AH66_RS19865	COG0471	metal ion transport
AH66_RS19875	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AH66_RS19900	COG3678	ATP-independent chaperone mediated protein folding
AH66_RS19905	COG0745	RESPONSE REGULATOR receiver
AH66_RS19910	COG2205	protein histidine kinase activity
AH66_RS19915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AH66_RS19915	COG2169	Transcriptional regulator
AH66_RS19920	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AH66_RS19925	COG1045	serine acetyltransferase
AH66_RS19940	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AH66_RS19945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AH66_RS19955	COG4942	peptidase
AH66_RS19970	COG0156	8-amino-7-oxononanoate synthase activity
AH66_RS19980	COG0859	PFAM glycosyl transferase family 9
AH66_RS19985	COG0859	PFAM glycosyl transferase family 9
AH66_RS19990	COG1519	Transferase
AH66_RS20025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AH66_RS20055	COG1561	YicC-like family, N-terminal region
AH66_RS20060	COG2860	membrane
AH66_RS20080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AH66_RS20085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AH66_RS20090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AH66_RS20100	COG0786	glutamate:sodium symporter activity
AH66_RS20105	COG2233	PERMEase
AH66_RS20110	COG2982	Protein involved in outer membrane biogenesis
AH66_RS20115	COG0456	acetyltransferase
AH66_RS20140	COG1011	Hydrolase
AH66_RS20150	COG0174	glutamine synthetase
AH66_RS20155	COG3852	Histidine kinase
AH66_RS20165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AH66_RS20185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AH66_RS20185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AH66_RS20190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AH66_RS20195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AH66_RS20200	COG3084	Protein conserved in bacteria
AH66_RS20210	COG1763	Mo-molybdopterin cofactor biosynthetic process
AH66_RS20215	COG3328	transposase activity
AH66_RS20240	COG2186	Transcriptional regulator
AH66_RS20245	COG0477	Major facilitator Superfamily
AH66_RS20260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AH66_RS20290	COG1522	sequence-specific DNA binding
AH66_RS20295	COG0716	FMN binding
AH66_RS20310	COG3312	ion transport
AH66_RS20365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AH66_RS20370	COG0573	inorganic phosphate transmembrane transporter activity
AH66_RS20375	COG0581	inorganic phosphate transmembrane transporter activity
AH66_RS20385	COG0704	Plays a role in the regulation of phosphate uptake
AH66_RS20395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AH66_RS20400	COG0765	amino acid transport
AH66_RS20405	COG0765	amino acid transport
AH66_RS20410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AH66_RS20420	COG2252	PERMEase
AH66_RS20450	COG0706	membrane insertase activity
AH66_RS20465	COG0230	Belongs to the bacterial ribosomal protein bL34 family