locus-tag	class	description
EGX46_RS00060	COG5599	Phosphatase
EGX46_RS00065	COG1317	bacterial-type flagellum organization
EGX46_RS00075	COG4669	(LipO)protein
EGX46_RS00110	COG1450	Type ii and iii secretion system protein
EGX46_RS00125	COG2207	Transcriptional regulator
EGX46_RS00135	COG4792	protein secretion
EGX46_RS00140	COG4791	protein targeting
EGX46_RS00145	COG4794	Type iii secretion
EGX46_RS00150	COG4790	Type iii secretion
EGX46_RS00200	COG4789	Type iii secretion
EGX46_RS00220	COG0457	Tetratricopeptide repeat
EGX46_RS00245	COG4886	Leucine-rich repeat (LRR) protein
EGX46_RS00255	COG3328	transposase activity
EGX46_RS00280	COG3177	Filamentation induced by cAMP protein fic
EGX46_RS00335	COG3609	addiction module antidote protein, CC2985 family
EGX46_RS00525	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGX46_RS00580	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGX46_RS00630	COG1309	transcriptional regulator
EGX46_RS00640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_RS00640	COG0493	'glutamate synthase
EGX46_RS00645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_RS00650	COG3383	formate dehydrogenase (NAD+) activity
EGX46_RS00665	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX46_RS00715	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EGX46_RS00725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX46_RS00730	COG1053	succinate dehydrogenase
EGX46_RS00745	COG1511	domain protein
EGX46_RS00745	COG3264	Mechanosensitive ion channel
EGX46_RS00765	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGX46_RS00785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX46_RS00790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGX46_RS00790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX46_RS00795	COG0802	atpase or kinase
EGX46_RS00800	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX46_RS00820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX46_RS00825	COG0330	HflC and HflK could
EGX46_RS00830	COG0330	HflC and HflK could
EGX46_RS00835	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EGX46_RS00850	COG0557	exoribonuclease II activity
EGX46_RS00855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX46_RS00860	COG1960	acyl-CoA dehydrogenase activity
EGX46_RS00865	COG3650	response to hydrogen peroxide
EGX46_RS00890	COG1401	restriction endodeoxyribonuclease activity
EGX46_RS00950	COG4269	membrane
EGX46_RS00960	COG2207	Transcriptional regulator
EGX46_RS00965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_RS00970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_RS00975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_RS00980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS00980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX46_RS00980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS01030	COG1070	Carbohydrate kinase
EGX46_RS01035	COG0859	PFAM glycosyl transferase family 9
EGX46_RS01050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_RS01055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_RS01100	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EGX46_RS01105	COG0456	acetyltransferase
EGX46_RS01115	COG2823	Periplasmic or secreted lipoprotein
EGX46_RS01125	COG4667	esterase of the alpha-beta hydrolase superfamily
EGX46_RS01130	COG0084	hydrolase, TatD family'
EGX46_RS01135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX46_RS01160	COG3726	membrane protein affecting hemolysin expression
EGX46_RS01165	COG0560	Phosphoserine phosphatase
EGX46_RS01205	COG2271	Major facilitator Superfamily
EGX46_RS01225	COG2831	hemolysin activation secretion protein
EGX46_RS01235	COG0747	negative chemotaxis
EGX46_RS01240	COG0601	transmembrane transport
EGX46_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_RS01250	COG0444	Belongs to the ABC transporter superfamily
EGX46_RS01255	COG4608	Belongs to the ABC transporter superfamily
EGX46_RS01260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGX46_RS01265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EGX46_RS01270	COG2199	diguanylate cyclase activity
EGX46_RS01270	COG2200	EAL domain
EGX46_RS01275	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX46_RS01295	COG0612	Peptidase, M16
EGX46_RS01300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_RS01305	COG1942	4-Oxalocrotonate Tautomerase
EGX46_RS01310	COG2200	EAL domain
EGX46_RS01315	COG2982	Protein involved in outer membrane biogenesis
EGX46_RS01320	COG2134	cdp-diacylglycerol pyrophosphatase
EGX46_RS01325	COG1295	ribonuclease BN
EGX46_RS01350	COG1929	Belongs to the glycerate kinase type-1 family
EGX46_RS01355	COG2610	gluconate transmembrane transporter activity
EGX46_RS01365	COG3835	regulator
EGX46_RS01370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX46_RS01375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGX46_RS01380	COG0339	signal peptide processing
EGX46_RS01400	COG0589	response to stress
EGX46_RS01415	COG0306	phosphate transporter
EGX46_RS01420	COG2081	HI0933 family
EGX46_RS01435	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS01450	COG0191	fructose-bisphosphate aldolase activity
EGX46_RS01475	COG1741	Belongs to the pirin family
EGX46_RS01480	COG1609	Transcriptional regulator
EGX46_RS01485	COG2610	gluconate transmembrane transporter activity
EGX46_RS01490	COG3265	gluconokinase activity
EGX46_RS01510	COG2095	MarC family integral membrane protein
EGX46_RS01515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX46_RS01545	COG3275	phosphorelay sensor kinase activity
EGX46_RS01570	COG0058	SHG alpha-glucan phosphorylase activity
EGX46_RS01575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX46_RS01625	COG0583	DNA-binding transcription factor activity
EGX46_RS01630	COG1741	Belongs to the pirin family
EGX46_RS01640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX46_RS01660	COG2823	Periplasmic or secreted lipoprotein
EGX46_RS01670	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EGX46_RS01680	COG2198	Histidine kinase
EGX46_RS01680	COG0784	Response regulator, receiver
EGX46_RS01680	COG5002	protein histidine kinase activity
EGX46_RS01690	COG1242	4 iron, 4 sulfur cluster binding
EGX46_RS01695	COG0070	glutamate synthase
EGX46_RS01695	COG0067	glutamate synthase
EGX46_RS01695	COG0069	glutamate synthase activity
EGX46_RS01700	COG0493	'glutamate synthase
EGX46_RS01710	COG2969	positive regulation of protein catabolic process
EGX46_RS01715	COG0625	glutathione transferase activity
EGX46_RS01735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGX46_RS01740	COG3105	Protein conserved in bacteria
EGX46_RS01745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX46_RS01755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX46_RS01765	COG5007	Belongs to the BolA IbaG family
EGX46_RS01770	COG3113	response to antibiotic
EGX46_RS01775	COG2854	intermembrane phospholipid transfer
EGX46_RS01780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX46_RS01785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX46_RS01790	COG1127	ABC transporter
EGX46_RS01795	COG0530	calcium, potassium:sodium antiporter activity
EGX46_RS01800	COG0517	IMP dehydrogenase activity
EGX46_RS01800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX46_RS01805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGX46_RS01810	COG3117	lipopolysaccharide transmembrane transporter activity
EGX46_RS01815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGX46_RS01820	COG1137	ATPase activity
EGX46_RS01825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGX46_RS01850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS01880	COG1609	Transcriptional regulator
EGX46_RS01885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_RS01885	COG1263	PTS System
EGX46_RS01890	COG0366	Alpha amylase catalytic
EGX46_RS01895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX46_RS01900	COG3783	Cytochrome b(562)
EGX46_RS01915	COG0312	modulator of DNA gyrase
EGX46_RS01925	COG2732	(Barnase) inhibitor
EGX46_RS01955	COG0583	DNA-binding transcription factor activity
EGX46_RS02005	COG0312	modulator of DNA gyrase
EGX46_RS02010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX46_RS02015	COG3164	Protein of unknown function
EGX46_RS02020	COG1530	ribonuclease E activity
EGX46_RS02025	COG0424	maF-like protein
EGX46_RS02030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGX46_RS02035	COG1792	Involved in formation and maintenance of cell shape
EGX46_RS02040	COG1077	Cell shape determining protein MreB Mrl
EGX46_RS02045	COG2200	EAL domain
EGX46_RS02045	COG2199	diguanylate cyclase activity
EGX46_RS02050	COG0604	alcohol dehydrogenase
EGX46_RS02055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGX46_RS02070	COG0511	ligase activity, forming carbon-carbon bonds
EGX46_RS02075	COG0439	Biotin carboxylase
EGX46_RS02080	COG3924	membrane
EGX46_RS02085	COG4145	pantothenate transmembrane transporter activity
EGX46_RS02095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX46_RS02100	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGX46_RS02130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX46_RS02140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX46_RS02145	COG3133	Outer membrane lipoprotein
EGX46_RS02155	COG1278	Cold shock
EGX46_RS02160	COG1278	Cold shock
EGX46_RS02180	COG0625	glutathione transferase activity
EGX46_RS02190	COG1069	ribulokinase activity
EGX46_RS02200	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS02205	COG1129	ABC transporter
EGX46_RS02215	COG1560	Kdo2-lipid A biosynthetic process
EGX46_RS02225	COG0025	NhaP-type Na H and K H
EGX46_RS02230	COG2252	PERMEase
EGX46_RS02235	COG3077	Addiction module antitoxin, RelB DinJ family
EGX46_RS02250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX46_RS02260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX46_RS02265	COG0431	NADPH-dependent FMN reductase
EGX46_RS02270	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX46_RS02275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_RS02280	COG1869	D-ribose catabolic process
EGX46_RS02285	COG2207	Transcriptional regulator
EGX46_RS02285	COG1917	Cupin 2, conserved barrel domain protein
EGX46_RS02290	COG0673	inositol 2-dehydrogenase activity
EGX46_RS02335	COG0250	Participates in transcription elongation, termination and antitermination
EGX46_RS02395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX46_RS02430	COG1515	deoxyribonuclease V activity
EGX46_RS02450	COG0151	Belongs to the GarS family
EGX46_RS02590	COG3047	cAMP biosynthetic process
EGX46_RS02590	COG2885	chlorophyll binding
EGX46_RS02610	COG0417	DNA replication proofreading
EGX46_RS02615	COG0586	Pfam SNARE associated Golgi protein
EGX46_RS02620	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EGX46_RS02625	COG1178	ABC-type Fe3 transport system permease component
EGX46_RS02630	COG4143	(ABC) transporter
EGX46_RS02665	COG2814	Major facilitator Superfamily
EGX46_RS02680	COG0473	3-isopropylmalate dehydrogenase activity
EGX46_RS02710	COG1022	Amp-dependent synthetase and ligase
EGX46_RS02720	COG0028	Belongs to the TPP enzyme family
EGX46_RS02740	COG1609	Transcriptional regulator
EGX46_RS02765	COG3116	cell division
EGX46_RS02770	COG0768	penicillin binding
EGX46_RS02775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX46_RS02780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX46_RS02795	COG0772	Belongs to the SEDS family
EGX46_RS02815	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX46_RS02820	COG0849	cell division
EGX46_RS02825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX46_RS02855	COG0494	nUDIX hydrolase
EGX46_RS02925	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGX46_RS02930	COG2224	Isocitrate lyase
EGX46_RS02960	COG0527	aspartate kinase activity
EGX46_RS02975	COG3833	ABC-type maltose transport systems, permease component
EGX46_RS02980	COG1175	transmembrane transport
EGX46_RS03065	COG0195	Participates in both transcription termination and antitermination
EGX46_RS03085	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX46_RS03095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX46_RS03110	COG1534	Rna-binding protein
EGX46_RS03120	COG2027	D-alanyl-D-alanine carboxypeptidase
EGX46_RS03125	COG0745	RESPONSE REGULATOR receiver
EGX46_RS03130	COG0642	Histidine kinase
EGX46_RS03140	COG0697	spore germination
EGX46_RS03155	COG0142	geranyltranstransferase activity
EGX46_RS03165	COG3423	Transcriptional regulator
EGX46_RS03190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX46_RS03195	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EGX46_RS03200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGX46_RS03205	COG2105	PFAM AIG2 family protein
EGX46_RS03210	COG2911	Protein conserved in bacteria
EGX46_RS03215	COG0729	surface antigen
EGX46_RS03225	COG1253	flavin adenine dinucleotide binding
EGX46_RS03235	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EGX46_RS03245	COG0737	Belongs to the 5'-nucleotidase family
EGX46_RS03255	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX46_RS03260	COG3061	Opacity-associated protein A
EGX46_RS03280	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX46_RS03290	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX46_RS03300	COG1073	alpha beta
EGX46_RS03340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGX46_RS03355	COG1629	transport
EGX46_RS03380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX46_RS03385	COG0678	peroxiredoxin activity
EGX46_RS03385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX46_RS03465	COG1879	ABC-type sugar transport system periplasmic component
EGX46_RS03470	COG1129	ABC transporter
EGX46_RS03475	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS03480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS03490	COG3085	chromosome segregation
EGX46_RS03515	COG3978	acetolactate synthase activity
EGX46_RS03520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX46_RS03560	COG0583	DNA-binding transcription factor activity
EGX46_RS03600	COG3121	Chaperone
EGX46_RS03615	COG3121	Chaperone
EGX46_RS03630	COG3328	transposase activity
EGX46_RS03640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX46_RS03665	COG3118	belongs to the thioredoxin family
EGX46_RS03670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX46_RS03675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX46_RS03680	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX46_RS03685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX46_RS03690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGX46_RS03695	COG1088	dTDP-glucose 4,6-dehydratase activity
EGX46_RS03700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGX46_RS03705	COG0456	acetyltransferase
EGX46_RS03710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX46_RS03715	COG2244	polysaccharide biosynthetic process
EGX46_RS03735	COG1113	amino acid transport
EGX46_RS03780	COG3071	HemY protein
EGX46_RS03785	COG2959	enzyme of heme biosynthesis
EGX46_RS03790	COG1587	Uroporphyrinogen-III synthase
EGX46_RS03805	COG3072	Adenylate cyclase
EGX46_RS03825	COG3159	Protein conserved in bacteria
EGX46_RS03830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGX46_RS03835	COG1011	Hydrolase
EGX46_RS03840	COG0210	DNA helicase
EGX46_RS03850	COG5441	Belongs to the UPF0261 family
EGX46_RS03855	COG5564	TIM-barrel signal transduction protein
EGX46_RS03870	COG2050	protein possibly involved in aromatic compounds catabolism
EGX46_RS03875	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EGX46_RS03880	COG0514	ATP-dependent DNA helicase (RecQ)
EGX46_RS03885	COG1280	lysine exporter protein (LysE YggA)
EGX46_RS03890	COG1280	lysine exporter protein (LysE YggA)
EGX46_RS03895	COG2267	carboxylic ester hydrolase activity
EGX46_RS03900	COG0561	phosphatase activity
EGX46_RS03910	COG0584	glycerophosphoryl diester phosphodiesterase
EGX46_RS03925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX46_RS03935	COG0247	lactate metabolic process
EGX46_RS03945	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX46_RS03960	COG3714	YhhN family
EGX46_RS03975	COG3776	membrane
EGX46_RS03980	COG0742	ribosomal rna small subunit methyltransferase
EGX46_RS03990	COG0552	protein localization to endoplasmic reticulum
EGX46_RS03990	COG0552	protein localization to endoplasmic reticulum
EGX46_RS03995	COG2884	Cell division ATP-binding protein ftsE
EGX46_RS04000	COG2177	Part of the ABC transporter FtsEX involved in
EGX46_RS04020	COG0683	leucine binding
EGX46_RS04045	COG4177	L-phenylalanine transmembrane transporter activity
EGX46_RS04055	COG0410	ABC transporter
EGX46_RS04115	COG0584	glycerophosphoryl diester phosphodiesterase
EGX46_RS04120	COG0679	Auxin Efflux Carrier
EGX46_RS04125	COG0697	spore germination
EGX46_RS04130	COG0583	DNA-binding transcription factor activity
EGX46_RS04140	COG0412	Dienelactone hydrolase
EGX46_RS04155	COG1966	Carbon starvation protein
EGX46_RS04160	COG0586	Pfam SNARE associated Golgi protein
EGX46_RS04165	COG1322	Protein conserved in bacteria
EGX46_RS04185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX46_RS04195	COG0805	protein transport
EGX46_RS04230	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX46_RS04245	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX46_RS04250	COG1609	Transcriptional regulator
EGX46_RS04260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX46_RS04270	COG4682	membrane
EGX46_RS04285	COG0527	aspartate kinase activity
EGX46_RS04285	COG0460	homoserine dehydrogenase
EGX46_RS04305	COG2211	Major facilitator Superfamily
EGX46_RS04355	COG2771	luxR family
EGX46_RS04360	COG3916	Acyl-homoserine-lactone synthase
EGX46_RS04490	COG1982	Orn Lys Arg decarboxylase major
EGX46_RS04495	COG1879	ABC-type sugar transport system periplasmic component
EGX46_RS04500	COG1129	ABC transporter
EGX46_RS04505	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS04510	COG4774	siderophore transport
EGX46_RS04535	COG1194	a g-specific adenine glycosylase
EGX46_RS04545	COG3171	Protein conserved in bacteria
EGX46_RS04560	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EGX46_RS04560	COG3064	Membrane
EGX46_RS04560	COG1073	alpha beta
EGX46_RS04565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX46_RS04570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX46_RS04580	COG0762	integral membrane protein
EGX46_RS04590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX46_RS04595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX46_RS04600	COG2805	Type II/IV secretion system protein
EGX46_RS04610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX46_RS04625	COG0189	ligase activity
EGX46_RS04630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX46_RS04635	COG2356	endonuclease I
EGX46_RS04650	COG1166	arginine decarboxylase activity
EGX46_RS04675	COG0501	Belongs to the peptidase M48B family
EGX46_RS04685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGX46_RS04710	COG0191	fructose-bisphosphate aldolase activity
EGX46_RS04760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX46_RS04765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX46_RS04790	COG0006	proline dipeptidase activity
EGX46_RS04795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX46_RS04800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX46_RS04840	COG5295	Hep Hag repeat protein
EGX46_RS04850	COG1272	protein, Hemolysin III
EGX46_RS04875	COG0745	RESPONSE REGULATOR receiver
EGX46_RS04880	COG2205	protein histidine kinase activity
EGX46_RS04885	COG4452	Inner membrane protein CreD
EGX46_RS04890	COG0716	FMN binding
EGX46_RS04895	COG4974	Belongs to the 'phage' integrase family
EGX46_RS04900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX46_RS04905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX46_RS04945	COG0582	viral genome integration into host DNA
EGX46_RS04970	COG2944	sequence-specific DNA binding
EGX46_RS05060	COG1695	Transcriptional regulator
EGX46_RS05065	COG0791	NLP P60 protein
EGX46_RS05075	COG1879	ABC-type sugar transport system periplasmic component
EGX46_RS05080	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS05085	COG1129	ABC transporter
EGX46_RS05095	COG2182	Extracellular solute-binding protein
EGX46_RS05100	COG1175	transmembrane transport
EGX46_RS05105	COG3833	ABC-type maltose transport systems, permease component
EGX46_RS05110	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EGX46_RS05115	COG1874	Beta-galactosidase
EGX46_RS05120	COG1263	PTS System
EGX46_RS05120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_RS05140	COG2271	Major facilitator Superfamily
EGX46_RS05170	COG3119	arylsulfatase activity
EGX46_RS05175	COG0641	radical SAM
EGX46_RS05185	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS05195	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS05200	COG3716	PTS system mannose fructose sorbose family IID component
EGX46_RS05205	COG3715	PTS system
EGX46_RS05210	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_RS05215	COG2222	sugar isomerase
EGX46_RS05225	COG1349	DNA-binding transcription factor activity
EGX46_RS05230	COG3119	arylsulfatase activity
EGX46_RS05280	COG0288	reversible hydration of carbon dioxide
EGX46_RS05305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX46_RS05330	COG2165	general secretion pathway protein
EGX46_RS05375	COG0840	transmembrane signaling receptor activity
EGX46_RS05390	COG0583	DNA-binding transcription factor activity
EGX46_RS05395	COG2814	Major facilitator Superfamily
EGX46_RS05400	COG0583	DNA-binding transcription factor activity
EGX46_RS05410	COG1609	Transcriptional regulator
EGX46_RS05440	COG0667	Aldo Keto reductase
EGX46_RS05510	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGX46_RS05520	COG1074	ATP-dependent DNA helicase activity
EGX46_RS05525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX46_RS05535	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX46_RS05550	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGX46_RS05555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX46_RS05560	COG2166	iron-sulfur cluster assembly
EGX46_RS05565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX46_RS05575	COG0583	DNA-binding transcription factor activity
EGX46_RS05580	COG2363	Small membrane protein
EGX46_RS05620	COG1611	Belongs to the LOG family
EGX46_RS05640	COG3098	single-species biofilm formation
EGX46_RS05645	COG0564	pseudouridine synthase activity
EGX46_RS05720	COG0575	Belongs to the CDS family
EGX46_RS05725	COG0750	zinc metalloprotease
EGX46_RS05740	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX46_RS05765	COG0587	DNA-directed DNA polymerase activity
EGX46_RS05775	COG0346	lactoylglutathione lyase activity
EGX46_RS05780	COG0037	tRNA processing
EGX46_RS05790	COG4568	rho-dependent transcription termination
EGX46_RS05800	COG4681	YaeQ
EGX46_RS05810	COG3015	lipoprotein NlpE involved in copper resistance
EGX46_RS05820	COG1720	tRNA m6t6A37 methyltransferase activity
EGX46_RS05830	COG1464	Belongs to the NlpA lipoprotein family
EGX46_RS05835	COG2011	ABC-type metal ion transport system permease component
EGX46_RS05845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX46_RS05880	COG0656	L-ascorbic acid biosynthetic process
EGX46_RS05895	COG1388	LysM domain
EGX46_RS05895	COG0741	lytic transglycosylase activity
EGX46_RS05900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX46_RS05905	COG2226	methyltransferase
EGX46_RS05925	COG1953	Uracil, thiamine, allantoin
EGX46_RS05950	COG3657	addiction module killer protein
EGX46_RS06010	COG0582	viral genome integration into host DNA
EGX46_RS06040	COG2867	negative regulation of translational initiation
EGX46_RS06050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX46_RS06055	COG0497	DNA recombination
EGX46_RS06060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX46_RS06075	COG2009	succinate dehydrogenase
EGX46_RS06080	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGX46_RS06085	COG1053	succinate dehydrogenase
EGX46_RS06095	COG0567	Dehydrogenase, E1 component
EGX46_RS06100	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX46_RS06110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX46_RS06115	COG1271	oxidase subunit
EGX46_RS06120	COG1294	oxidase, subunit
EGX46_RS06125	COG4890	Cyd operon protein YbgT
EGX46_RS06130	COG3790	cyd operon protein YbgE
EGX46_RS06135	COG0824	Thioesterase
EGX46_RS06140	COG0811	peptide transport
EGX46_RS06145	COG0848	biopolymer transport protein
EGX46_RS06150	COG3064	Membrane
EGX46_RS06150	COG3064	Membrane
EGX46_RS06160	COG2885	chlorophyll binding
EGX46_RS06165	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EGX46_RS06195	COG1230	cation diffusion facilitator family transporter
EGX46_RS06200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX46_RS06225	COG0814	amino acid
EGX46_RS06230	COG1349	DNA-binding transcription factor activity
EGX46_RS06240	COG0671	phosphoesterase, PA-phosphatase related
EGX46_RS06275	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGX46_RS06280	COG3842	ATPase activity
EGX46_RS06285	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX46_RS06290	COG1177	transmembrane transport
EGX46_RS06305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS06330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS06335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS06340	COG1120	ATPase activity
EGX46_RS06360	COG4160	amino acid transport
EGX46_RS06365	COG4215	(ABC) transporter
EGX46_RS06370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS06375	COG1126	abc transporter atp-binding protein
EGX46_RS06380	COG1605	Chorismate mutase
EGX46_RS06390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_RS06395	COG0702	epimerase
EGX46_RS06400	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EGX46_RS06410	COG0028	Belongs to the TPP enzyme family
EGX46_RS06415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_RS06425	COG2431	L-lysine efflux transmembrane transporter activity
EGX46_RS06430	COG3593	DNA synthesis involved in DNA repair
EGX46_RS06435	COG2990	Protein conserved in bacteria
EGX46_RS06440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_RS06450	COG1278	Cold shock
EGX46_RS06465	COG0542	response to heat
EGX46_RS06480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGX46_RS06490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX46_RS06500	COG0492	ferredoxin-NADP+ reductase activity
EGX46_RS06510	COG3107	peptidoglycan biosynthetic process
EGX46_RS06510	COG1674	ftsk spoiiie
EGX46_RS06520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX46_RS06535	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGX46_RS06545	COG1882	Formate acetyltransferase
EGX46_RS06550	COG2116	formate transmembrane transporter activity
EGX46_RS06555	COG1944	ATP diphosphatase activity
EGX46_RS06560	COG0252	asparaginase activity
EGX46_RS06565	COG5295	Hep Hag repeat protein
EGX46_RS06565	COG5295	Hep Hag repeat protein
EGX46_RS06590	COG0539	negative regulation of cytoplasmic translation
EGX46_RS06605	COG2333	competence protein COMEC
EGX46_RS06605	COG0658	competence protein
EGX46_RS06650	COG1278	Cold shock
EGX46_RS06670	COG3173	Aminoglycoside phosphotransferase
EGX46_RS06685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGX46_RS06715	COG2989	Protein conserved in bacteria
EGX46_RS06720	COG3108	Peptidase M15
EGX46_RS06725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX46_RS06735	COG1448	Aminotransferase
EGX46_RS06755	COG0308	aminopeptidase N
EGX46_RS06770	COG0633	Ferredoxin
EGX46_RS06770	COG3217	Mosc domain protein beta barrel domain protein
EGX46_RS06780	COG0488	(ABC) transporter
EGX46_RS06785	COG2995	paraquat-inducible protein a
EGX46_RS06790	COG3008	intermembrane lipid transfer
EGX46_RS06790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX46_RS06795	COG3009	Protein conserved in bacteria
EGX46_RS06805	COG3130	regulation of translation
EGX46_RS06835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_RS06850	COG1067	ATP-dependent peptidase activity
EGX46_RS06875	COG3070	regulator of competence-specific genes
EGX46_RS06880	COG1289	transmembrane transporter activity
EGX46_RS06885	COG3304	Inner membrane component domain
EGX46_RS06890	COG0210	DNA helicase
EGX46_RS06905	COG1832	CoA-binding protein
EGX46_RS06925	COG2920	part of a sulfur-relay system
EGX46_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS06960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX46_RS06965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_RS06970	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS06975	COG3425	synthase
EGX46_RS06985	COG1024	Enoyl-CoA hydratase
EGX46_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS07000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX46_RS07005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGX46_RS07150	COG0488	(ABC) transporter
EGX46_RS07160	COG3328	transposase activity
EGX46_RS07170	COG0303	'Molybdopterin
EGX46_RS07180	COG1136	(ABC) transporter
EGX46_RS07210	COG0583	DNA-binding transcription factor activity
EGX46_RS07215	COG0477	Major facilitator Superfamily
EGX46_RS07225	COG2311	Membrane
EGX46_RS07240	COG4211	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS07245	COG2949	membrane
EGX46_RS07260	COG1346	cytolysis
EGX46_RS07270	COG2814	Major facilitator Superfamily
EGX46_RS07305	COG0489	protein tyrosine kinase activity
EGX46_RS07320	COG2982	Protein involved in outer membrane biogenesis
EGX46_RS07325	COG1253	flavin adenine dinucleotide binding
EGX46_RS07330	COG4114	ferric iron reductase
EGX46_RS07335	COG0076	glutamate decarboxylase activity
EGX46_RS07340	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGX46_RS07355	COG1120	ATPase activity
EGX46_RS07360	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS07365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS07370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX46_RS07385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX46_RS07390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX46_RS07400	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGX46_RS07400	COG0140	phosphoribosyl-ATP diphosphatase activity
EGX46_RS07420	COG0131	Imidazoleglycerol-phosphate dehydratase
EGX46_RS07420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX46_RS07430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX46_RS07445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_RS07450	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS07455	COG1129	ABC transporter
EGX46_RS07460	COG1129	ABC transporter
EGX46_RS07465	COG0371	Dehydrogenase
EGX46_RS07475	COG0531	amino acid
EGX46_RS07485	COG2925	Exonuclease
EGX46_RS07500	COG3328	transposase activity
EGX46_RS07505	COG1388	LysM domain
EGX46_RS07505	COG1470	cell adhesion involved in biofilm formation
EGX46_RS07510	COG2271	Major facilitator Superfamily
EGX46_RS07515	COG3011	Protein conserved in bacteria
EGX46_RS07520	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS07530	COG4948	Mandelate Racemase Muconate Lactonizing
EGX46_RS07550	COG0534	Mate efflux family protein
EGX46_RS07570	COG3122	Protein conserved in bacteria
EGX46_RS07595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGX46_RS07615	COG2223	nitrite transmembrane transporter activity
EGX46_RS07620	COG3328	transposase activity
EGX46_RS07645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX46_RS07655	COG1686	Belongs to the peptidase S11 family
EGX46_RS07660	COG0277	FAD linked oxidase domain protein
EGX46_RS07680	COG2261	transglycosylase associated protein
EGX46_RS07690	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EGX46_RS07705	COG4807	Protein conserved in bacteria
EGX46_RS07725	COG1122	ATPase activity
EGX46_RS07750	COG2897	thiosulfate sulfurtransferase activity
EGX46_RS07755	COG1732	Glycine betaine
EGX46_RS07760	COG1732	Glycine betaine
EGX46_RS07765	COG1174	glycine betaine transport
EGX46_RS07770	COG1125	glycine betaine transport
EGX46_RS07775	COG1174	glycine betaine transport
EGX46_RS07780	COG0531	amino acid
EGX46_RS07785	COG1982	Orn Lys Arg decarboxylase major
EGX46_RS07795	COG0697	spore germination
EGX46_RS07840	COG0814	amino acid
EGX46_RS07860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_RS07885	COG0784	Response regulator, receiver
EGX46_RS07885	COG2205	protein histidine kinase activity
EGX46_RS07895	COG2198	Histidine kinase
EGX46_RS07895	COG0642	Histidine kinase
EGX46_RS07900	COG2198	Histidine kinase
EGX46_RS07900	COG0642	Histidine kinase
EGX46_RS07905	COG2223	nitrite transmembrane transporter activity
EGX46_RS07940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX46_RS07985	COG3395	kinase activity
EGX46_RS07990	COG0235	Class ii aldolase
EGX46_RS07995	COG1349	DNA-binding transcription factor activity
EGX46_RS08000	COG3622	Belongs to the hyi family
EGX46_RS08020	COG4386	tail sheath protein
EGX46_RS08060	COG3299	homolog of phage Mu protein gp47
EGX46_RS08080	COG1737	Transcriptional regulator
EGX46_RS08085	COG2723	6-phospho-beta-galactosidase activity
EGX46_RS08135	COG3083	sulfuric ester hydrolase activity
EGX46_RS08140	COG3082	Protein of unknown function (DUF1414)
EGX46_RS08165	COG1061	Type III restriction enzyme res subunit
EGX46_RS08170	COG1187	pseudouridine synthase activity
EGX46_RS08175	COG2814	Major facilitator Superfamily
EGX46_RS08185	COG4172	Belongs to the ABC transporter superfamily
EGX46_RS08190	COG4239	(ABC) transporter, permease
EGX46_RS08195	COG4174	ABC transporter (Permease)
EGX46_RS08200	COG4166	transmembrane transport
EGX46_RS08205	COG2200	EAL domain
EGX46_RS08210	COG0791	NLP P60 protein
EGX46_RS08215	COG0671	phosphoesterase, PA-phosphatase related
EGX46_RS08220	COG0523	cobalamin synthesis protein
EGX46_RS08230	COG2186	Transcriptional regulator
EGX46_RS08235	COG0246	Mannitol dehydrogenase
EGX46_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS08300	COG1129	ABC transporter
EGX46_RS08310	COG0494	nUDIX hydrolase
EGX46_RS08320	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX46_RS08325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_RS08325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX46_RS08325	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGX46_RS08330	COG3710	Transcriptional regulator
EGX46_RS08345	COG3121	Chaperone
EGX46_RS08350	COG3188	usher protein
EGX46_RS08360	COG2855	membrane
EGX46_RS08365	COG0583	DNA-binding transcription factor activity
EGX46_RS08370	COG0833	amino acid
EGX46_RS08380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS08390	COG4771	TonB-dependent receptor
EGX46_RS08400	COG0625	glutathione transferase activity
EGX46_RS08425	COG2011	ABC-type metal ion transport system permease component
EGX46_RS08465	COG2017	converts alpha-aldose to the beta-anomer
EGX46_RS08480	COG1085	galactose-1-phosphate uridylyltransferase
EGX46_RS08485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX46_RS08495	COG1119	ATPase activity
EGX46_RS08505	COG2005	Transcriptional regulator
EGX46_RS08505	COG3585	molybdate ion transport
EGX46_RS08515	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX46_RS08520	COG4149	molybdate abc transporter
EGX46_RS08530	COG0561	phosphatase activity
EGX46_RS08555	COG2226	methyltransferase
EGX46_RS08565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX46_RS08575	COG4628	conserved protein (DUF2132)
EGX46_RS08580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX46_RS08585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX46_RS08595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGX46_RS08600	COG0314	molybdopterin synthase activity
EGX46_RS08605	COG0670	Belongs to the BI1 family
EGX46_RS08630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX46_RS08635	COG0583	DNA-binding transcription factor activity
EGX46_RS08645	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGX46_RS08650	COG2211	Major facilitator Superfamily
EGX46_RS08680	COG1902	pentaerythritol trinitrate reductase activity
EGX46_RS08700	COG0842	Transport permease protein
EGX46_RS08705	COG0842	Transport permease protein
EGX46_RS08710	COG1131	(ABC) transporter
EGX46_RS08720	COG1309	transcriptional regulator
EGX46_RS08725	COG0513	Belongs to the DEAD box helicase family
EGX46_RS08760	COG3328	transposase activity
EGX46_RS08815	COG1132	(ABC) transporter
EGX46_RS08830	COG2207	Transcriptional regulator
EGX46_RS08870	COG1113	amino acid transport
EGX46_RS08895	COG1496	oxidoreductase activity
EGX46_RS08900	COG2226	methyltransferase
EGX46_RS08910	COG3447	MASE1 domain protein
EGX46_RS08910	COG5001	Diguanylate cyclase
EGX46_RS08910	COG5002	protein histidine kinase activity
EGX46_RS08930	COG3716	PTS system mannose fructose sorbose family IID component
EGX46_RS08935	COG3715	PTS system
EGX46_RS08940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_RS08940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS08945	COG1253	flavin adenine dinucleotide binding
EGX46_RS08955	COG1846	Transcriptional regulator
EGX46_RS08970	COG1012	belongs to the aldehyde dehydrogenase family
EGX46_RS08975	COG3384	dioxygenase
EGX46_RS08985	COG3971	2-oxopent-4-enoate hydratase activity
EGX46_RS09000	COG2368	4-hydroxyphenylacetate
EGX46_RS09010	COG1760	l-serine dehydratase
EGX46_RS09035	COG0513	Belongs to the DEAD box helicase family
EGX46_RS09040	COG3141	response to X-ray
EGX46_RS09055	COG1770	oligopeptidase
EGX46_RS09080	COG1528	Iron-storage protein
EGX46_RS09085	COG2372	response to copper ion
EGX46_RS09120	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX46_RS09125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX46_RS09150	COG3418	PFAM FlgN family protein
EGX46_RS09155	COG2747	anti-sigma28 factor FlgM
EGX46_RS09165	COG1815	bacterial-type flagellum-dependent cell motility
EGX46_RS09170	COG1558	bacterial-type flagellum-dependent cell motility
EGX46_RS09210	COG1256	bacterial-type flagellum assembly
EGX46_RS09220	COG2390	Transcriptional regulator
EGX46_RS09225	COG3347	Dehydrogenase
EGX46_RS09225	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS09230	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS09240	COG1129	ABC transporter
EGX46_RS09245	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS09250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_RS09270	COG1987	bacterial-type flagellum assembly
EGX46_RS09295	COG1580	Controls the rotational direction of flagella during chemotaxis
EGX46_RS09310	COG1157	protein secretion by the type III secretion system
EGX46_RS09330	COG1677	Flagellar hook-basal body complex protein FliE
EGX46_RS09350	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EGX46_RS09355	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EGX46_RS09360	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EGX46_RS09395	COG1191	sigma factor activity
EGX46_RS09410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS09415	COG0765	amino acid transport
EGX46_RS09420	COG1126	abc transporter atp-binding protein
EGX46_RS09445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX46_RS09445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX46_RS09445	COG0506	proline dehydrogenase activity
EGX46_RS09460	COG0672	)-iron permease
EGX46_RS09465	COG2822	iron ion transport
EGX46_RS09485	COG1113	amino acid transport
EGX46_RS09510	COG3136	membrane protein required for alginate biosynthesis
EGX46_RS09520	COG2197	response regulator
EGX46_RS09665	COG2188	Transcriptional regulator
EGX46_RS09675	COG0673	inositol 2-dehydrogenase activity
EGX46_RS09685	COG1175	transmembrane transport
EGX46_RS09690	COG0395	ABC-type sugar transport system, permease component
EGX46_RS09695	COG3842	ATPase activity
EGX46_RS09765	COG4771	TonB-dependent receptor
EGX46_RS09770	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGX46_RS09790	COG3433	isochorismatase activity
EGX46_RS09790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_RS09790	COG2226	methyltransferase
EGX46_RS09805	COG1132	(ABC) transporter
EGX46_RS09810	COG2814	Major facilitator Superfamily
EGX46_RS09815	COG1169	isochorismate synthase
EGX46_RS09820	COG0582	viral genome integration into host DNA
EGX46_RS09830	COG3121	Chaperone
EGX46_RS09840	COG3188	usher protein
EGX46_RS09855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS09855	COG2205	protein histidine kinase activity
EGX46_RS09865	COG0427	acetyl-CoA hydrolase
EGX46_RS09870	COG2030	dehydratase
EGX46_RS09935	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX46_RS09940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX46_RS09950	COG1349	DNA-binding transcription factor activity
EGX46_RS09960	COG2066	Belongs to the glutaminase family
EGX46_RS09970	COG0672	)-iron permease
EGX46_RS09985	COG0577	efflux transmembrane transporter activity
EGX46_RS09985	COG1136	(ABC) transporter
EGX46_RS09995	COG0577	efflux transmembrane transporter activity
EGX46_RS09995	COG1136	(ABC) transporter
EGX46_RS10015	COG0006	proline dipeptidase activity
EGX46_RS10020	COG0457	Tetratricopeptide repeat
EGX46_RS10025	COG0726	polysaccharide deacetylase
EGX46_RS10025	COG1649	PFAM Uncharacterised BCR, COG1649
EGX46_RS10030	COG1215	transferase activity, transferring glycosyl groups
EGX46_RS10035	COG3658	cytochrome
EGX46_RS10050	COG1702	phosphate starvation-inducible protein PhoH
EGX46_RS10055	COG0387	Pfam Sodium calcium exchanger
EGX46_RS10060	COG3850	Histidine kinase
EGX46_RS10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX46_RS10135	COG0402	S-adenosylhomocysteine deaminase activity
EGX46_RS10155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_RS10200	COG3328	transposase activity
EGX46_RS10225	COG0500	methyltransferase
EGX46_RS10265	COG5002	protein histidine kinase activity
EGX46_RS10320	COG0012	GTP binding
EGX46_RS10335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX46_RS10360	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX46_RS10380	COG0659	secondary active sulfate transmembrane transporter activity
EGX46_RS10395	COG0659	secondary active sulfate transmembrane transporter activity
EGX46_RS10420	COG3833	ABC-type maltose transport systems, permease component
EGX46_RS10425	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX46_RS10445	COG0584	glycerophosphoryl diester phosphodiesterase
EGX46_RS10450	COG1940	carbohydrate kinase activity
EGX46_RS10465	COG3381	protein complex oligomerization
EGX46_RS10480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX46_RS10490	COG0728	peptidoglycan biosynthetic process
EGX46_RS10510	COG3102	Protein conserved in bacteria
EGX46_RS10530	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EGX46_RS10535	COG1801	Protein of unknown function DUF72
EGX46_RS10545	COG0494	nUDIX hydrolase
EGX46_RS10585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX46_RS10595	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EGX46_RS10600	COG0739	heme binding
EGX46_RS10605	COG1560	Kdo2-lipid A biosynthetic process
EGX46_RS10615	COG0469	pyruvate kinase activity
EGX46_RS10620	COG1737	Transcriptional regulator
EGX46_RS10625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX46_RS10635	COG0800	Aldolase
EGX46_RS10650	COG0251	oxidation-reduction process
EGX46_RS10655	COG1199	ATP-dependent helicase activity
EGX46_RS10665	COG3065	identical protein binding
EGX46_RS10675	COG0318	PFAM AMP-dependent synthetase and ligase
EGX46_RS10680	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGX46_RS10685	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGX46_RS10690	COG2894	cell division
EGX46_RS10705	COG2951	lytic endotransglycosylase activity
EGX46_RS10710	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX46_RS10720	COG0582	viral genome integration into host DNA
EGX46_RS10885	COG3328	transposase activity
EGX46_RS10895	COG1104	cysteine desulfurase activity
EGX46_RS10930	COG2719	SpoVR family
EGX46_RS10940	COG2814	Major facilitator Superfamily
EGX46_RS10950	COG0583	DNA-binding transcription factor activity
EGX46_RS10965	COG2766	serine protein kinase
EGX46_RS10975	COG3713	MltA-interacting MipA family protein
EGX46_RS10995	COG3139	Protein of unknown function (DUF1315)
EGX46_RS11000	COG1335	isochorismatase
EGX46_RS11005	COG0252	asparaginase activity
EGX46_RS11010	COG0616	signal peptide processing
EGX46_RS11015	COG0778	Nitroreductase
EGX46_RS11020	COG0709	Synthesizes selenophosphate from selenide and ATP
EGX46_RS11025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX46_RS11035	COG0494	nUDIX hydrolase
EGX46_RS11040	COG0708	Exodeoxyribonuclease III
EGX46_RS11045	COG0583	DNA-binding transcription factor activity
EGX46_RS11065	COG3328	transposase activity
EGX46_RS11070	COG0788	formyltetrahydrofolate deformylase activity
EGX46_RS11080	COG0745	RESPONSE REGULATOR receiver
EGX46_RS11115	COG1012	belongs to the aldehyde dehydrogenase family
EGX46_RS11115	COG1454	alcohol dehydrogenase
EGX46_RS11125	COG2095	MarC family integral membrane protein
EGX46_RS11135	COG0601	transmembrane transport
EGX46_RS11140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_RS11145	COG0444	Belongs to the ABC transporter superfamily
EGX46_RS11150	COG4608	Belongs to the ABC transporter superfamily
EGX46_RS11190	COG2350	Protein conserved in bacteria
EGX46_RS11195	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EGX46_RS11200	COG3328	transposase activity
EGX46_RS11240	COG3047	cAMP biosynthetic process
EGX46_RS11260	COG0134	indole-3-glycerol-phosphate synthase activity
EGX46_RS11260	COG0135	phosphoribosylanthranilate isomerase activity
EGX46_RS11270	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX46_RS11295	COG0009	L-threonylcarbamoyladenylate synthase
EGX46_RS11300	COG1187	pseudouridine synthase activity
EGX46_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS11315	COG0616	signal peptide processing
EGX46_RS11335	COG0583	DNA-binding transcription factor activity
EGX46_RS11345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX46_RS11355	COG0671	phosphoesterase, PA-phosphatase related
EGX46_RS11360	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EGX46_RS11365	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGX46_RS11380	COG0023	Translation Initiation Factor
EGX46_RS11400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX46_RS11405	COG2879	small protein
EGX46_RS11410	COG1966	Carbon starvation protein
EGX46_RS11420	COG2271	Major facilitator Superfamily
EGX46_RS11425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_RS11430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX46_RS11440	COG4659	FMN binding
EGX46_RS11445	COG4658	electron transport chain
EGX46_RS11450	COG2207	Transcriptional regulator
EGX46_RS11450	COG3708	Transcriptional regulator
EGX46_RS11485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_RS11490	COG2274	protein secretion by the type I secretion system
EGX46_RS11505	COG1879	ABC-type sugar transport system periplasmic component
EGX46_RS11510	COG1129	ABC transporter
EGX46_RS11515	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS11525	COG0673	inositol 2-dehydrogenase activity
EGX46_RS11530	COG0385	Bile acid
EGX46_RS11540	COG5339	Protein conserved in bacteria
EGX46_RS11550	COG0114	fumarate hydratase activity
EGX46_RS11560	COG2814	Major facilitator Superfamily
EGX46_RS11565	COG0583	DNA-binding transcription factor activity
EGX46_RS11570	COG1940	carbohydrate kinase activity
EGX46_RS11575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX46_RS11615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX46_RS11620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX46_RS11650	COG0028	Belongs to the TPP enzyme family
EGX46_RS11655	COG0440	acetolactate synthase activity
EGX46_RS11660	COG1011	Hydrolase
EGX46_RS11680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX46_RS11685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX46_RS11690	COG0589	response to stress
EGX46_RS11695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EGX46_RS11700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGX46_RS11715	COG0531	amino acid
EGX46_RS11725	COG0745	RESPONSE REGULATOR receiver
EGX46_RS11730	COG2205	protein histidine kinase activity
EGX46_RS11735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EGX46_RS11770	COG3038	cytochrome b561
EGX46_RS11785	COG3591	Belongs to the peptidase S1B family
EGX46_RS11830	COG2390	Transcriptional regulator
EGX46_RS11835	COG0246	Mannitol dehydrogenase
EGX46_RS11840	COG3784	Protein of unknown function (DUF1318)
EGX46_RS11850	COG2911	Protein conserved in bacteria
EGX46_RS11855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX46_RS11860	COG3187	Heat shock protein
EGX46_RS11865	COG3042	response to heat
EGX46_RS11870	COG1285	pathogenesis
EGX46_RS11880	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX46_RS11880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX46_RS11880	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX46_RS11880	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX46_RS11890	COG0657	acetylesterase activity
EGX46_RS11910	COG4166	transmembrane transport
EGX46_RS11915	COG2866	Carboxypeptidase
EGX46_RS11920	COG4948	Mandelate Racemase Muconate Lactonizing
EGX46_RS11925	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX46_RS11940	COG5642	Protein of unknown function (DUF2384)
EGX46_RS11945	COG5654	RES domain protein
EGX46_RS11955	COG3106	COG3106 Predicted ATPase
EGX46_RS11965	COG1983	PspC domain protein
EGX46_RS11975	COG1842	Phage shock protein A
EGX46_RS11980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EGX46_RS12000	COG4166	transmembrane transport
EGX46_RS12005	COG4168	peptide transport system, permease
EGX46_RS12010	COG4171	peptide transport system, permease
EGX46_RS12020	COG4172	Belongs to the ABC transporter superfamily
EGX46_RS12025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX46_RS12025	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX46_RS12030	COG3104	oligopeptide transport
EGX46_RS12065	COG3895	Periplasmic Protein
EGX46_RS12075	COG3133	Outer membrane lipoprotein
EGX46_RS12090	COG4989	oxidoreductase activity
EGX46_RS12095	COG3313	Fe-S protein
EGX46_RS12100	COG2194	sulfuric ester hydrolase activity
EGX46_RS12105	COG1309	transcriptional regulator
EGX46_RS12110	COG1902	pentaerythritol trinitrate reductase activity
EGX46_RS12120	COG0346	lactoylglutathione lyase activity
EGX46_RS12125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX46_RS12135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGX46_RS12145	COG0791	NLP P60 protein
EGX46_RS12165	COG0583	DNA-binding transcription factor activity
EGX46_RS12170	COG2814	Major facilitator Superfamily
EGX46_RS12175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGX46_RS12180	COG0307	riboflavin synthase, alpha
EGX46_RS12235	COG1376	ErfK ybiS ycfS ynhG family protein
EGX46_RS12235	COG1388	LysM domain
EGX46_RS12250	COG0719	Fe-S assembly protein
EGX46_RS12255	COG0396	ATPase activity
EGX46_RS12260	COG0719	Fe-S assembly protein
EGX46_RS12265	COG0316	Belongs to the HesB IscA family
EGX46_RS12275	COG2050	protein possibly involved in aromatic compounds catabolism
EGX46_RS12280	COG0277	FAD linked oxidase domain protein
EGX46_RS12280	COG0247	lactate metabolic process
EGX46_RS12285	COG0628	permease
EGX46_RS12295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX46_RS12295	COG0574	Belongs to the PEP-utilizing enzyme family
EGX46_RS12325	COG0791	NLP P60 protein
EGX46_RS12375	COG0386	Belongs to the glutathione peroxidase family
EGX46_RS12390	COG0776	regulation of translation
EGX46_RS12395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX46_RS12395	COG0072	phenylalanine-tRNA ligase activity
EGX46_RS12430	COG4249	Peptidase C14 caspase catalytic subunit p20
EGX46_RS12455	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX46_RS12460	COG1121	(ABC) transporter
EGX46_RS12465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX46_RS12470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX46_RS12480	COG3001	Fructosamine kinase
EGX46_RS12490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_RS12495	COG3328	transposase activity
EGX46_RS12500	COG1917	Cupin 2, conserved barrel domain protein
EGX46_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS12540	COG1175	transmembrane transport
EGX46_RS12545	COG0395	ABC-type sugar transport system, permease component
EGX46_RS12550	COG3842	ATPase activity
EGX46_RS12555	COG1653	transport
EGX46_RS12560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX46_RS12565	COG1988	membrane-bound metal-dependent
EGX46_RS12570	COG1823	symporter activity
EGX46_RS12575	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX46_RS12585	COG0823	Involved in the tonB-independent uptake of proteins
EGX46_RS12590	COG2814	Major facilitator Superfamily
EGX46_RS12595	COG3121	Chaperone
EGX46_RS12610	COG3121	Chaperone
EGX46_RS12615	COG3539	Fimbrial protein
EGX46_RS12630	COG0793	Belongs to the peptidase S41A family
EGX46_RS12640	COG1956	GAF domain-containing protein
EGX46_RS12645	COG2995	paraquat-inducible protein a
EGX46_RS12650	COG3008	intermembrane lipid transfer
EGX46_RS12670	COG3121	Chaperone
EGX46_RS12730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX46_RS12740	COG5295	Hep Hag repeat protein
EGX46_RS12750	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX46_RS12760	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGX46_RS12765	COG0745	RESPONSE REGULATOR receiver
EGX46_RS12775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGX46_RS12780	COG0840	transmembrane signaling receptor activity
EGX46_RS12785	COG0840	transmembrane signaling receptor activity
EGX46_RS12805	COG2964	Protein conserved in bacteria
EGX46_RS12815	COG0251	oxidation-reduction process
EGX46_RS12820	COG2271	Major facilitator Superfamily
EGX46_RS12825	COG0835	chemotaxis
EGX46_RS12830	COG2198	Histidine kinase
EGX46_RS12830	COG0643	Histidine kinase
EGX46_RS12835	COG1360	Flagellar Motor Protein
EGX46_RS12860	COG1285	pathogenesis
EGX46_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS12905	COG3321	synthase
EGX46_RS12905	COG0604	alcohol dehydrogenase
EGX46_RS12915	COG1522	sequence-specific DNA binding
EGX46_RS12935	COG1733	regulation of RNA biosynthetic process
EGX46_RS12940	COG0702	epimerase
EGX46_RS12945	COG0840	transmembrane signaling receptor activity
EGX46_RS12960	COG0538	isocitrate dehydrogenase activity
EGX46_RS12985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX46_RS12995	COG0745	RESPONSE REGULATOR receiver
EGX46_RS13005	COG2850	peptidyl-arginine hydroxylation
EGX46_RS13030	COG1940	carbohydrate kinase activity
EGX46_RS13035	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX46_RS13045	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX46_RS13050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX46_RS13055	COG3134	Outer membrane lipoprotein
EGX46_RS13065	COG3328	transposase activity
EGX46_RS13085	COG1252	NADH dehydrogenase
EGX46_RS13095	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX46_RS13110	COG5633	Lipoprotein
EGX46_RS13115	COG0537	adenosine 5'-monophosphoramidase activity
EGX46_RS13120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX46_RS13145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_RS13145	COG1263	PTS System
EGX46_RS13150	COG0084	hydrolase, TatD family'
EGX46_RS13155	COG0470	DNA polymerase III
EGX46_RS13165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGX46_RS13170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX46_RS13180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_RS13210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX46_RS13215	COG1399	metal-binding, possibly nucleic acid-binding protein
EGX46_RS13220	COG0424	maF-like protein
EGX46_RS13230	COG0564	pseudouridine synthase activity
EGX46_RS13240	COG1530	ribonuclease E activity
EGX46_RS13255	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGX46_RS13280	COG3328	transposase activity
EGX46_RS13295	COG3328	transposase activity
EGX46_RS13300	COG2197	response regulator
EGX46_RS13310	COG0628	permease
EGX46_RS13330	COG3916	Acyl-homoserine-lactone synthase
EGX46_RS13335	COG2771	luxR family
EGX46_RS13340	COG0583	DNA-binding transcription factor activity
EGX46_RS13350	COG0477	Major facilitator Superfamily
EGX46_RS13360	COG0667	Aldo Keto reductase
EGX46_RS13385	COG1203	CRISPR-associated helicase, Cas3
EGX46_RS13390	COG1518	maintenance of DNA repeat elements
EGX46_RS13395	COG0668	transmembrane transport
EGX46_RS13420	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EGX46_RS13425	COG0395	ABC-type sugar transport system, permease component
EGX46_RS13440	COG1609	Transcriptional regulator
EGX46_RS13450	COG3842	ATPase activity
EGX46_RS13460	COG3210	domain, Protein
EGX46_RS13465	COG3210	domain, Protein
EGX46_RS13485	COG3210	domain, Protein
EGX46_RS13505	COG3210	domain, Protein
EGX46_RS13510	COG2831	hemolysin activation secretion protein
EGX46_RS13515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_RS13520	COG4638	Rieske (2fe-2S)
EGX46_RS13525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX46_RS13535	COG0473	3-isopropylmalate dehydrogenase activity
EGX46_RS13540	COG0583	DNA-binding transcription factor activity
EGX46_RS13545	COG1609	Transcriptional regulator
EGX46_RS13550	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS13555	COG1129	ABC transporter
EGX46_RS13560	COG1879	ABC-type sugar transport system periplasmic component
EGX46_RS13595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS13600	COG0765	amino acid transport
EGX46_RS13605	COG1126	abc transporter atp-binding protein
EGX46_RS13655	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX46_RS13670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX46_RS13685	COG1169	isochorismate synthase
EGX46_RS13695	COG4575	ribosome binding
EGX46_RS13710	COG0129	dihydroxy-acid dehydratase activity
EGX46_RS13725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX46_RS13730	COG1609	Transcriptional regulator
EGX46_RS13735	COG1649	PFAM Uncharacterised BCR, COG1649
EGX46_RS13740	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS13745	COG3265	gluconokinase activity
EGX46_RS13750	COG2731	YhcH YjgK YiaL family protein
EGX46_RS13765	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX46_RS13770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX46_RS13780	COG0839	Belongs to the complex I subunit 6 family
EGX46_RS13795	COG1034	ATP synthesis coupled electron transport
EGX46_RS13815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX46_RS13825	COG0583	DNA-binding transcription factor activity
EGX46_RS13830	COG0436	Aminotransferase
EGX46_RS13845	COG0471	metal ion transport
EGX46_RS13845	COG0490	domain, Protein
EGX46_RS13850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_RS13870	COG0280	phosphate acetyltransferase
EGX46_RS13870	COG0857	belongs to the CobB CobQ family
EGX46_RS13875	COG1609	Transcriptional regulator
EGX46_RS13890	COG3037	sugar-specific permease SgaT UlaA
EGX46_RS13895	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGX46_RS13910	COG1090	epimerase
EGX46_RS13915	COG4598	ABC transporter
EGX46_RS13920	COG4160	amino acid transport
EGX46_RS13925	COG4215	(ABC) transporter
EGX46_RS13930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS13950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX46_RS13955	COG1286	toxin biosynthetic process
EGX46_RS13960	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EGX46_RS13965	COG0285	dihydrofolate synthase activity
EGX46_RS13975	COG0586	Pfam SNARE associated Golgi protein
EGX46_RS13985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX46_RS14000	COG0697	spore germination
EGX46_RS14015	COG1794	racemase activity, acting on amino acids and derivatives
EGX46_RS14020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX46_RS14035	COG3101	peptidyl-lysine hydroxylation
EGX46_RS14040	COG0730	response to heat
EGX46_RS14055	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX46_RS14065	COG2062	phosphohistidine phosphatase, SixA
EGX46_RS14080	COG3691	Protein conserved in bacteria
EGX46_RS14095	COG3088	subunit of a heme lyase
EGX46_RS14095	COG4235	cytochrome complex assembly
EGX46_RS14100	COG4235	cytochrome complex assembly
EGX46_RS14100	COG3088	subunit of a heme lyase
EGX46_RS14105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX46_RS14110	COG1138	Cytochrome C-type biogenesis protein
EGX46_RS14120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX46_RS14125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX46_RS14130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX46_RS14150	COG1704	LemA family
EGX46_RS14160	COG2824	Alkylphosphonate utilization operon protein PhnA
EGX46_RS14250	COG3188	usher protein
EGX46_RS14255	COG3328	transposase activity
EGX46_RS14265	COG3188	usher protein
EGX46_RS14270	COG3121	Chaperone
EGX46_RS14330	COG2951	lytic endotransglycosylase activity
EGX46_RS14365	COG0243	molybdopterin cofactor binding
EGX46_RS14370	COG0437	4 iron, 4 sulfur cluster binding
EGX46_RS14375	COG3302	dmso reductase anchor subunit
EGX46_RS14390	COG3381	protein complex oligomerization
EGX46_RS14420	COG3038	cytochrome b561
EGX46_RS14425	COG0436	Aminotransferase
EGX46_RS14450	COG0667	Aldo Keto reductase
EGX46_RS14465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX46_RS14530	COG3530	Putative quorum-sensing-regulated virulence factor
EGX46_RS14545	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EGX46_RS14555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS14580	COG2205	protein histidine kinase activity
EGX46_RS14585	COG0745	RESPONSE REGULATOR receiver
EGX46_RS14590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_RS14605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX46_RS14625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX46_RS14635	COG5002	protein histidine kinase activity
EGX46_RS14635	COG3850	Histidine kinase
EGX46_RS14640	COG0745	RESPONSE REGULATOR receiver
EGX46_RS14655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGX46_RS14660	COG4208	sulfate ABC transporter
EGX46_RS14665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGX46_RS14670	COG4150	thiosulfate binding
EGX46_RS14680	COG1737	Transcriptional regulator
EGX46_RS14690	COG2731	YhcH YjgK YiaL family protein
EGX46_RS14710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX46_RS14715	COG2837	iron assimilation
EGX46_RS14725	COG3111	PFAM Bacterial OB fold (BOF) protein
EGX46_RS14790	COG3005	denitrification pathway
EGX46_RS14795	COG3043	anaerobic respiration
EGX46_RS14805	COG3062	negative regulation of establishment of protein localization
EGX46_RS14810	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_RS14810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_RS14815	COG2197	response regulator
EGX46_RS14825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_RS14835	COG1988	membrane-bound metal-dependent
EGX46_RS14840	COG0641	radical SAM
EGX46_RS14845	COG3119	arylsulfatase activity
EGX46_RS14855	COG3842	ATPase activity
EGX46_RS14860	COG1175	transmembrane transport
EGX46_RS14875	COG1393	Belongs to the ArsC family
EGX46_RS14885	COG1876	peptidase activity
EGX46_RS14910	COG2321	neutral zinc metallopeptidase
EGX46_RS14930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGX46_RS14940	COG2716	regulation of RNA biosynthetic process
EGX46_RS14945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX46_RS14960	COG0628	permease
EGX46_RS14965	COG4783	chaperone-mediated protein folding
EGX46_RS14970	COG1393	Belongs to the ArsC family
EGX46_RS14995	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX46_RS15000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX46_RS15015	COG0581	inorganic phosphate transmembrane transporter activity
EGX46_RS15025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX46_RS15040	COG2239	Acts as a magnesium transporter
EGX46_RS15045	COG0443	Heat shock 70 kDa protein
EGX46_RS15065	COG1177	transmembrane transport
EGX46_RS15070	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX46_RS15080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGX46_RS15090	COG3842	ATPase activity
EGX46_RS15120	COG0745	RESPONSE REGULATOR receiver
EGX46_RS15125	COG3422	double-strand break repair
EGX46_RS15130	COG0826	peptidase U32
EGX46_RS15155	COG0351	phosphomethylpyrimidine kinase
EGX46_RS15170	COG3328	transposase activity
EGX46_RS15220	COG0516	GMP reductase activity
EGX46_RS15220	COG0517	IMP dehydrogenase activity
EGX46_RS15235	COG1645	bacterial-type flagellum-dependent swarming motility
EGX46_RS15250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX46_RS15255	COG2976	Protein conserved in bacteria
EGX46_RS15300	COG3468	outer membrane autotransporter barrel domain protein
EGX46_RS15305	COG3468	outer membrane autotransporter barrel domain protein
EGX46_RS15330	COG2975	iron-sulfur cluster assembly
EGX46_RS15335	COG0633	Ferredoxin
EGX46_RS15340	COG0443	Heat shock 70 kDa protein
EGX46_RS15360	COG0822	iron-sulfur transferase activity
EGX46_RS15365	COG1104	cysteine desulfurase activity
EGX46_RS15385	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX46_RS15390	COG3683	transport system, periplasmic component
EGX46_RS15395	COG3711	transcriptional antiterminator
EGX46_RS15400	COG2814	Major facilitator Superfamily
EGX46_RS15420	COG1017	nitric oxide dioxygenase activity
EGX46_RS15420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_RS15430	COG0347	Belongs to the P(II) protein family
EGX46_RS15435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX46_RS15435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX46_RS15440	COG2204	response regulator
EGX46_RS15445	COG3170	Tfp pilus assembly protein FimV
EGX46_RS15450	COG2205	protein histidine kinase activity
EGX46_RS15500	COG0560	Phosphoserine phosphatase
EGX46_RS15510	COG1737	Transcriptional regulator
EGX46_RS15515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX46_RS15530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGX46_RS15550	COG2113	Glycine betaine
EGX46_RS15555	COG4176	ABC-type proline glycine betaine transport system permease component
EGX46_RS15560	COG4175	Glycine betaine
EGX46_RS15565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX46_RS15595	COG3328	transposase activity
EGX46_RS15620	COG1278	Cold shock
EGX46_RS15625	COG0747	negative chemotaxis
EGX46_RS15635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_RS15640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGX46_RS15645	COG1124	(ABC) transporter
EGX46_RS15650	COG0831	urea catabolic process
EGX46_RS15675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGX46_RS15685	COG4413	Urea transporter
EGX46_RS15690	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX46_RS15705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX46_RS15715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX46_RS15725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX46_RS15730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX46_RS15735	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX46_RS15740	COG2169	Transcriptional regulator
EGX46_RS15740	COG1917	Cupin 2, conserved barrel domain protein
EGX46_RS15765	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EGX46_RS15770	COG0033	Phosphoglucomutase
EGX46_RS15785	COG0745	RESPONSE REGULATOR receiver
EGX46_RS15790	COG2205	protein histidine kinase activity
EGX46_RS15830	COG3272	Protein of unknown function (DUF1722)
EGX46_RS15840	COG5212	phosphodiesterase
EGX46_RS15845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX46_RS15855	COG1984	allophanate hydrolase subunit 2
EGX46_RS15905	COG0513	Belongs to the DEAD box helicase family
EGX46_RS15915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGX46_RS15930	COG3026	antisigma factor binding
EGX46_RS15935	COG3086	response to oxidative stress
EGX46_RS15990	COG0582	viral genome integration into host DNA
EGX46_RS16000	COG0596	Alpha beta hydrolase
EGX46_RS16020	COG0735	belongs to the Fur family
EGX46_RS16055	COG2190	(PTS) system
EGX46_RS16055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX46_RS16055	COG1263	PTS System
EGX46_RS16065	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX46_RS16070	COG1846	Transcriptional regulator
EGX46_RS16070	COG1940	carbohydrate kinase activity
EGX46_RS16075	COG0647	UMP catabolic process
EGX46_RS16080	COG0367	asparagine synthase
EGX46_RS16120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX46_RS16125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX46_RS16130	COG1702	phosphate starvation-inducible protein PhoH
EGX46_RS16140	COG4535	Mg2 and Co2 transporter CorC
EGX46_RS16145	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGX46_RS16155	COG0765	amino acid transport
EGX46_RS16160	COG0765	amino acid transport
EGX46_RS16165	COG1126	abc transporter atp-binding protein
EGX46_RS16170	COG2888	peptidyl-tyrosine sulfation
EGX46_RS16185	COG1466	dna polymerase III delta subunit
EGX46_RS16195	COG0799	negative regulation of ribosome biogenesis
EGX46_RS16205	COG0768	penicillin binding
EGX46_RS16210	COG0772	Belongs to the SEDS family
EGX46_RS16215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX46_RS16235	COG1686	Belongs to the peptidase S11 family
EGX46_RS16260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX46_RS16265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX46_RS16275	COG1278	Cold shock
EGX46_RS16280	COG2197	response regulator
EGX46_RS16305	COG5265	(ABC) transporter
EGX46_RS16315	COG3718	enzyme involved in inositol metabolism
EGX46_RS16330	COG0673	inositol 2-dehydrogenase activity
EGX46_RS16335	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS16340	COG1129	ABC transporter
EGX46_RS16355	COG3962	Belongs to the TPP enzyme family
EGX46_RS16380	COG2373	Large extracellular alpha-helical protein
EGX46_RS16385	COG4953	penicillin-binding protein 1C
EGX46_RS16390	COG3328	transposase activity
EGX46_RS16400	COG3423	Transcriptional regulator
EGX46_RS16455	COG3328	transposase activity
EGX46_RS16470	COG1472	Belongs to the glycosyl hydrolase 3 family
EGX46_RS16480	COG0656	L-ascorbic acid biosynthetic process
EGX46_RS16485	COG0667	Aldo Keto reductase
EGX46_RS16525	COG0671	phosphoesterase, PA-phosphatase related
EGX46_RS16525	COG2453	phosphatase
EGX46_RS16530	COG2267	carboxylic ester hydrolase activity
EGX46_RS16540	COG4589	Belongs to the CDS family
EGX46_RS16545	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX46_RS16560	COG0582	viral genome integration into host DNA
EGX46_RS16595	COG2501	S4 domain
EGX46_RS16615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX46_RS16630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX46_RS16635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX46_RS16640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGX46_RS16645	COG4181	ATPase activity
EGX46_RS16650	COG2755	lipolytic protein G-D-S-L family
EGX46_RS16655	COG0300	oxidoreductase activity
EGX46_RS16660	COG3118	belongs to the thioredoxin family
EGX46_RS16665	COG0330	HflC and HflK could
EGX46_RS16670	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGX46_RS16675	COG0789	Transcriptional regulator
EGX46_RS16680	COG2217	Heavy metal translocating P-type atpase
EGX46_RS16685	COG3735	TraB family
EGX46_RS16690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX46_RS16705	COG2223	nitrite transmembrane transporter activity
EGX46_RS16710	COG4651	solute:proton antiporter activity
EGX46_RS16710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX46_RS16715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_RS16720	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX46_RS16740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_RS16790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX46_RS16815	COG0543	2 iron, 2 sulfur cluster binding
EGX46_RS16815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX46_RS16845	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX46_RS16855	COG2832	Protein of unknown function (DUF454)
EGX46_RS16895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGX46_RS16900	COG1309	transcriptional regulator
EGX46_RS16905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_RS16910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_RS16920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX46_RS16945	COG3695	enzyme binding
EGX46_RS16950	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EGX46_RS16955	COG1946	Acyl-CoA thioesterase
EGX46_RS16960	COG0004	ammonium transporteR
EGX46_RS16965	COG0347	Belongs to the P(II) protein family
EGX46_RS16970	COG1132	(ABC) transporter
EGX46_RS16975	COG1132	(ABC) transporter
EGX46_RS16980	COG1522	sequence-specific DNA binding
EGX46_RS16995	COG4533	DNA binding
EGX46_RS17005	COG0824	Thioesterase
EGX46_RS17010	COG1555	photosystem II stabilization
EGX46_RS17015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX46_RS17020	COG0776	regulation of translation
EGX46_RS17025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGX46_RS17050	COG0271	Belongs to the BolA IbaG family
EGX46_RS17055	COG3056	Lipoprotein
EGX46_RS17060	COG2223	nitrite transmembrane transporter activity
EGX46_RS17070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX46_RS17075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX46_RS17080	COG1845	cytochrome c oxidase, subunit III
EGX46_RS17085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX46_RS17095	COG2814	Major facilitator Superfamily
EGX46_RS17110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX46_RS17115	COG0693	protein deglycase activity
EGX46_RS17130	COG0142	geranyltranstransferase activity
EGX46_RS17145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGX46_RS17150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGX46_RS17165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX46_RS17165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX46_RS17200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX46_RS17205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX46_RS17210	COG1862	Preprotein translocase
EGX46_RS17230	COG0450	alkyl hydroperoxide reductase
EGX46_RS17255	COG0366	Alpha amylase catalytic
EGX46_RS17275	COG5002	protein histidine kinase activity
EGX46_RS17280	COG0745	RESPONSE REGULATOR receiver
EGX46_RS17285	COG0420	3'-5' exonuclease activity
EGX46_RS17290	COG0419	ATPase involved in DNA repair
EGX46_RS17315	COG1940	carbohydrate kinase activity
EGX46_RS17345	COG2226	methyltransferase
EGX46_RS17395	COG0583	DNA-binding transcription factor activity
EGX46_RS17400	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX46_RS17420	COG1477	protein flavinylation
EGX46_RS17440	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX46_RS17445	COG1805	sodium ion transport
EGX46_RS17460	COG3034	peptidoglycan biosynthetic process
EGX46_RS17465	COG0121	glutamine amidotransferase
EGX46_RS17475	COG1960	acyl-CoA dehydrogenase activity
EGX46_RS17485	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
EGX46_RS17505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX46_RS17525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX46_RS17535	COG0765	amino acid transport
EGX46_RS17575	COG2814	Major facilitator Superfamily
EGX46_RS17580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX46_RS17590	COG1846	Transcriptional regulator
EGX46_RS17595	COG1566	PFAM secretion protein HlyD family protein
EGX46_RS17600	COG2814	Major facilitator Superfamily
EGX46_RS17605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX46_RS17610	COG3118	belongs to the thioredoxin family
EGX46_RS17615	COG3148	PFAM DTW domain containing protein
EGX46_RS17620	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX46_RS17620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX46_RS17620	COG1042	CoA-binding domain protein
EGX46_RS17625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX46_RS17630	COG5544	Lipoprotein
EGX46_RS17670	COG0542	response to heat
EGX46_RS17680	COG0564	pseudouridine synthase activity
EGX46_RS17690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX46_RS17695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX46_RS17710	COG1605	Chorismate mutase
EGX46_RS17710	COG0077	Prephenate dehydratase
EGX46_RS17740	COG0529	Catalyzes the synthesis of activated sulfate
EGX46_RS17780	COG1388	LysM domain
EGX46_RS17780	COG4942	peptidase
EGX46_RS17785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX46_RS17795	COG0698	ribose 5-phosphate isomerase
EGX46_RS17800	COG1063	alcohol dehydrogenase
EGX46_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
EGX46_RS17810	COG2376	Dihydroxyacetone kinase
EGX46_RS17825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX46_RS17845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS17850	COG1858	cytochrome C peroxidase
EGX46_RS17860	COG4771	TonB-dependent receptor
EGX46_RS17875	COG0024	Methionine aminopeptidase
EGX46_RS17885	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX46_RS17885	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX46_RS17890	COG1070	Carbohydrate kinase
EGX46_RS17895	COG3623	hexulose-6-phosphate isomerase
EGX46_RS17900	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS17905	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS17910	COG1129	ABC transporter
EGX46_RS17925	COG1349	DNA-binding transcription factor activity
EGX46_RS17930	COG0235	Class ii aldolase
EGX46_RS17935	COG0243	molybdopterin cofactor binding
EGX46_RS17940	COG0437	4 iron, 4 sulfur cluster binding
EGX46_RS17945	COG3302	dmso reductase anchor subunit
EGX46_RS17950	COG3381	protein complex oligomerization
EGX46_RS17955	COG3038	cytochrome b561
EGX46_RS17960	COG3783	Cytochrome b(562)
EGX46_RS17970	COG1879	ABC-type sugar transport system periplasmic component
EGX46_RS17980	COG1129	ABC transporter
EGX46_RS17985	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX46_RS17990	COG3959	Transketolase, thiamine diphosphate binding domain
EGX46_RS17995	COG3958	Transketolase
EGX46_RS18000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX46_RS18045	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGX46_RS18080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_RS18085	COG1238	metal cluster binding
EGX46_RS18090	COG2918	glutathione biosynthetic process
EGX46_RS18105	COG4536	flavin adenine dinucleotide binding
EGX46_RS18110	COG4137	Cytochrome C assembly protein
EGX46_RS18115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX46_RS18145	COG3137	Salt-induced outer membrane protein
EGX46_RS18155	COG3279	Response regulator of the LytR AlgR family
EGX46_RS18160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX46_RS18165	COG1605	Chorismate mutase
EGX46_RS18165	COG0287	Prephenate dehydrogenase
EGX46_RS18225	COG0720	synthase
EGX46_RS18230	COG0602	queuosine metabolic process
EGX46_RS18250	COG3956	TIGRFAM MazG family protein
EGX46_RS18255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX46_RS18260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX46_RS18270	COG4999	Histidine kinase
EGX46_RS18270	COG2205	protein histidine kinase activity
EGX46_RS18270	COG3437	response regulator, receiver
EGX46_RS18270	COG3850	Histidine kinase
EGX46_RS18275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX46_RS18295	COG2860	membrane
EGX46_RS18315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS18320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX46_RS18325	COG1120	ATPase activity
EGX46_RS18330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX46_RS18335	COG1643	Atp-dependent helicase
EGX46_RS18340	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX46_RS18365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX46_RS18370	COG0617	tRNA 3'-terminal CCA addition
EGX46_RS18375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX46_RS18400	COG0842	Transport permease protein
EGX46_RS18405	COG1131	(ABC) transporter
EGX46_RS18410	COG0288	reversible hydration of carbon dioxide
EGX46_RS18415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGX46_RS18420	COG2132	Multicopper oxidase
EGX46_RS18440	COG0697	spore germination
EGX46_RS18450	COG1049	propionate catabolic process, 2-methylcitrate cycle
EGX46_RS18465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX46_RS18470	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX46_RS18475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGX46_RS18480	COG2186	Transcriptional regulator
EGX46_RS18490	COG1113	amino acid transport
EGX46_RS18495	COG3725	Membrane protein required for beta-lactamase induction
EGX46_RS18500	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX46_RS18510	COG4969	Belongs to the N-Me-Phe pilin family
EGX46_RS18515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX46_RS18520	COG1459	type II secretion system
EGX46_RS18575	COG0582	viral genome integration into host DNA
EGX46_RS18585	COG0795	lipopolysaccharide-transporting ATPase activity
EGX46_RS18590	COG0795	lipopolysaccharide-transporting ATPase activity
EGX46_RS18600	COG2927	DNA polymerase III (CHI subunit)
EGX46_RS18605	COG0525	valine-tRNA ligase activity
EGX46_RS18615	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EGX46_RS18625	COG2731	YhcH YjgK YiaL family protein
EGX46_RS18635	COG0601	transmembrane transport
EGX46_RS18640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX46_RS18645	COG0444	Belongs to the ABC transporter superfamily
EGX46_RS18650	COG4608	Belongs to the ABC transporter superfamily
EGX46_RS18665	COG2188	Transcriptional regulator
EGX46_RS18670	COG3624	Phosphonate C-P lyase system protein PhnG
EGX46_RS18675	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EGX46_RS18680	COG3626	phosphonate metabolism
EGX46_RS18685	COG3627	carbon phosphorus lyase activity
EGX46_RS18690	COG4107	phosphonate C-P lyase system protein PhnK
EGX46_RS18695	COG4778	phosphonate C-P lyase system protein PhnL
EGX46_RS18700	COG3454	Phosphonate metabolism
EGX46_RS18705	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EGX46_RS18710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX46_RS18715	COG0702	epimerase
EGX46_RS18730	COG3842	ATPase activity
EGX46_RS18735	COG0395	ABC-type sugar transport system, permease component
EGX46_RS18740	COG1175	transmembrane transport
EGX46_RS18745	COG1653	transport
EGX46_RS18765	COG3153	acetyltransferase
EGX46_RS18770	COG3154	lipid carrier protein
EGX46_RS18780	COG0826	peptidase U32
EGX46_RS18785	COG0826	peptidase U32
EGX46_RS18795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX46_RS18805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX46_RS18830	COG0513	Belongs to the DEAD box helicase family
EGX46_RS18860	COG2423	ornithine cyclodeaminase activity
EGX46_RS18865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX46_RS18880	COG5645	(Lipo)protein
EGX46_RS18900	COG3977	Valine--pyruvate aminotransferase
EGX46_RS18920	COG0366	Alpha amylase catalytic
EGX46_RS18940	COG2885	chlorophyll binding
EGX46_RS18950	COG2818	Glycosylase
EGX46_RS18970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX46_RS18970	COG2213	PTS system mannitol-specific
EGX46_RS18980	COG3722	fumarate hydratase activity
EGX46_RS19020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX46_RS19030	COG0243	molybdopterin cofactor binding
EGX46_RS19030	COG3383	formate dehydrogenase (NAD+) activity
EGX46_RS19035	COG3383	formate dehydrogenase (NAD+) activity
EGX46_RS19035	COG0243	molybdopterin cofactor binding
EGX46_RS19040	COG0437	4 iron, 4 sulfur cluster binding
EGX46_RS19045	COG2864	formate dehydrogenase
EGX46_RS19060	COG3276	selenocysteine insertion sequence binding
EGX46_RS19140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EGX46_RS19145	COG1191	sigma factor activity
EGX46_RS19170	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EGX46_RS19190	COG3710	Transcriptional regulator
EGX46_RS19210	COG1256	bacterial-type flagellum assembly
EGX46_RS19220	COG1706	bacterial-type flagellum-dependent cell motility
EGX46_RS19230	COG4786	Flagellar basal body rod
EGX46_RS19235	COG4787	bacterial-type flagellum-dependent cell motility
EGX46_RS19240	COG1749	Flagellar hook protein flgE
EGX46_RS19245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGX46_RS19250	COG1558	bacterial-type flagellum-dependent cell motility
EGX46_RS19255	COG1815	bacterial-type flagellum-dependent cell motility
EGX46_RS19260	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EGX46_RS19315	COG1677	Flagellar hook-basal body complex protein FliE
EGX46_RS19340	COG1987	bacterial-type flagellum assembly
EGX46_RS19345	COG1684	flagellar biosynthetic protein fliR
EGX46_RS19350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX46_RS19370	COG4592	Periplasmic binding protein
EGX46_RS19405	COG4964	Belongs to the GSP D family
EGX46_RS19410	COG4964	Belongs to the GSP D family
EGX46_RS19465	COG0848	biopolymer transport protein
EGX46_RS19470	COG0811	peptide transport
EGX46_RS19475	COG0626	cystathionine gamma-synthase activity
EGX46_RS19485	COG2207	Transcriptional regulator
EGX46_RS19490	COG1979	alcohol dehydrogenase
EGX46_RS19500	COG0656	L-ascorbic acid biosynthetic process
EGX46_RS19515	COG2132	Multicopper oxidase
EGX46_RS19530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX46_RS19540	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX46_RS19545	COG0583	DNA-binding transcription factor activity
EGX46_RS19555	COG3150	esterase
EGX46_RS19565	COG3151	Protein conserved in bacteria
EGX46_RS19570	COG0494	nUDIX hydrolase
EGX46_RS19575	COG1538	Outer membrane efflux protein
EGX46_RS19590	COG0754	glutathionylspermidine amidase activity
EGX46_RS19595	COG3384	dioxygenase
EGX46_RS19615	COG0531	amino acid
EGX46_RS19630	COG3025	triphosphatase activity
EGX46_RS19635	COG4991	sh3 domain protein
EGX46_RS19650	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGX46_RS19670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGX46_RS19675	COG0358	DNA primase activity
EGX46_RS19770	COG0251	oxidation-reduction process
EGX46_RS19790	COG0436	Aminotransferase
EGX46_RS19815	COG1289	transmembrane transporter activity
EGX46_RS19835	COG0395	ABC-type sugar transport system, permease component
EGX46_RS19845	COG2182	Extracellular solute-binding protein
EGX46_RS19850	COG1609	Transcriptional regulator
EGX46_RS19855	COG3459	Glycosyltransferase 36 associated
EGX46_RS19860	COG3842	ATPase activity
EGX46_RS19880	COG3210	domain, Protein
EGX46_RS19885	COG3210	domain, Protein
EGX46_RS19910	COG3210	domain, Protein
EGX46_RS19915	COG2831	hemolysin activation secretion protein
EGX46_RS19920	COG4245	von Willebrand factor, type A
EGX46_RS19935	COG4245	von Willebrand factor, type A
EGX46_RS19955	COG3247	response to pH
EGX46_RS19960	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX46_RS19960	COG1902	pentaerythritol trinitrate reductase activity
EGX46_RS19975	COG1451	nucleotide metabolic process
EGX46_RS19980	COG0673	inositol 2-dehydrogenase activity
EGX46_RS20005	COG2721	sulfolactate sulfo-lyase activity
EGX46_RS20020	COG2271	Major facilitator Superfamily
EGX46_RS20035	COG0586	Pfam SNARE associated Golgi protein
EGX46_RS20055	COG4575	ribosome binding
EGX46_RS20060	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EGX46_RS20070	COG2259	Doxx family
EGX46_RS20075	COG0435	Glutathione S-transferase
EGX46_RS20090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGX46_RS20105	COG0551	DNA topoisomerase type I activity
EGX46_RS20115	COG0758	DNA mediated transformation
EGX46_RS20145	COG3036	rescue of stalled ribosome
EGX46_RS20150	COG0789	Transcriptional regulator
EGX46_RS20165	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX46_RS20180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX46_RS20185	COG0201	protein transport
EGX46_RS20195	COG1841	ribosomal large subunit assembly
EGX46_RS20235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX46_RS20240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX46_RS20250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX46_RS20265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX46_RS20275	COG0089	rRNA binding
EGX46_RS20290	COG0051	transcription antitermination factor activity, RNA binding
EGX46_RS20340	COG0049	tRNA binding
EGX46_RS20345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX46_RS20365	COG2964	Protein conserved in bacteria
EGX46_RS20370	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX46_RS20385	COG1047	Peptidyl-prolyl cis-trans
EGX46_RS20390	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGX46_RS20410	COG1216	Glycosyl transferase, family 2
EGX46_RS20420	COG2175	clavaminate synthase activity
EGX46_RS20425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX46_RS20435	COG4521	taurine ABC transporter
EGX46_RS20445	COG0429	hydrolase of the alpha beta-hydrolase fold
EGX46_RS20455	COG3954	Phosphoribulokinase
EGX46_RS20465	COG1765	OsmC-like protein
EGX46_RS20475	COG1289	transmembrane transporter activity
EGX46_RS20490	COG0433	COG0433 Predicted ATPase
EGX46_RS20495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX46_RS20500	COG1486	melibiose metabolic process
EGX46_RS20520	COG0402	S-adenosylhomocysteine deaminase activity
EGX46_RS20525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX46_RS20545	COG0180	Tryptophanyl-tRNA synthetase
EGX46_RS20550	COG0546	phosphoglycolate phosphatase activity
EGX46_RS20555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX46_RS20580	COG4796	Type ii and iii secretion system protein
EGX46_RS20610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGX46_RS20615	COG0494	nUDIX hydrolase
EGX46_RS20625	COG1011	Hydrolase
EGX46_RS20630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX46_RS20655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX46_RS20660	COG2183	response to ionizing radiation
EGX46_RS20665	COG1918	ferrous iron import across plasma membrane
EGX46_RS20700	COG1640	4-alpha-glucanotransferase
EGX46_RS20705	COG0058	SHG alpha-glucan phosphorylase activity
EGX46_RS20710	COG0058	SHG alpha-glucan phosphorylase activity
EGX46_RS20730	COG1349	DNA-binding transcription factor activity
EGX46_RS20760	COG5001	Diguanylate cyclase
EGX46_RS20770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX46_RS20830	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EGX46_RS20835	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX46_RS20840	COG4771	TonB-dependent receptor
EGX46_RS20860	COG3433	isochorismatase activity
EGX46_RS20860	COG2226	methyltransferase
EGX46_RS20860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_RS20870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX46_RS20870	COG3433	isochorismatase activity
EGX46_RS20870	COG2226	methyltransferase
EGX46_RS20895	COG2375	cellular response to nickel ion
EGX46_RS20895	COG1132	(ABC) transporter
EGX46_RS20900	COG1132	(ABC) transporter
EGX46_RS20915	COG2610	gluconate transmembrane transporter activity
EGX46_RS20930	COG3501	Rhs element vgr protein
EGX46_RS20940	COG3209	COG3209 Rhs family protein
EGX46_RS20960	COG0471	metal ion transport
EGX46_RS21045	COG3501	Rhs element vgr protein
EGX46_RS21090	COG3501	Rhs element vgr protein
EGX46_RS21105	COG3209	COG3209 Rhs family protein
EGX46_RS21160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX46_RS21195	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EGX46_RS21200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX46_RS21215	COG1739	Uncharacterized protein family UPF0029
EGX46_RS21240	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGX46_RS21320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX46_RS21325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX46_RS21330	COG1494	fructose-1,6-bisphosphatase
EGX46_RS21340	COG3152	Membrane
EGX46_RS21355	COG0583	DNA-binding transcription factor activity
EGX46_RS21360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX46_RS21365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGX46_RS21370	COG0471	metal ion transport
EGX46_RS21380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGX46_RS21410	COG3678	ATP-independent chaperone mediated protein folding
EGX46_RS21415	COG0745	RESPONSE REGULATOR receiver
EGX46_RS21420	COG2205	protein histidine kinase activity
EGX46_RS21425	COG2169	Transcriptional regulator
EGX46_RS21425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX46_RS21430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGX46_RS21435	COG1045	serine acetyltransferase
EGX46_RS21455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX46_RS21460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX46_RS21470	COG4942	peptidase
EGX46_RS21485	COG0156	8-amino-7-oxononanoate synthase activity
EGX46_RS21495	COG0859	PFAM glycosyl transferase family 9
EGX46_RS21500	COG0859	PFAM glycosyl transferase family 9
EGX46_RS21505	COG1519	Transferase
EGX46_RS21545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX46_RS21570	COG1561	YicC-like family, N-terminal region
EGX46_RS21575	COG2860	membrane
EGX46_RS21595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX46_RS21600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX46_RS21605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX46_RS21615	COG0786	glutamate:sodium symporter activity
EGX46_RS21620	COG2233	PERMEase
EGX46_RS21625	COG2982	Protein involved in outer membrane biogenesis
EGX46_RS21630	COG0456	acetyltransferase
EGX46_RS21660	COG1011	Hydrolase
EGX46_RS21670	COG0174	glutamine synthetase
EGX46_RS21690	COG3852	Histidine kinase
EGX46_RS21700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX46_RS21730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX46_RS21730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX46_RS21735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX46_RS21740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGX46_RS21745	COG3084	Protein conserved in bacteria
EGX46_RS21755	COG1763	Mo-molybdopterin cofactor biosynthetic process
EGX46_RS21760	COG3328	transposase activity
EGX46_RS21795	COG2186	Transcriptional regulator
EGX46_RS21800	COG0477	Major facilitator Superfamily
EGX46_RS21815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX46_RS21865	COG1522	sequence-specific DNA binding
EGX46_RS21870	COG0716	FMN binding
EGX46_RS21890	COG3312	ion transport
EGX46_RS21950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX46_RS21955	COG0573	inorganic phosphate transmembrane transporter activity
EGX46_RS21960	COG0581	inorganic phosphate transmembrane transporter activity
EGX46_RS21970	COG0704	Plays a role in the regulation of phosphate uptake
EGX46_RS21980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX46_RS21985	COG0765	amino acid transport
EGX46_RS21990	COG0765	amino acid transport
EGX46_RS21995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX46_RS22005	COG2252	PERMEase
EGX46_RS22035	COG0706	membrane insertase activity
EGX46_RS22050	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGX46_RS22070	COG0592	DNA-directed DNA polymerase activity
EGX46_RS22080	COG0187	DNA topoisomerase II activity
EGX46_RS22085	COG0561	phosphatase activity
EGX46_RS22105	COG3274	enterobacterial common antigen metabolic process
EGX46_RS22120	COG3121	Chaperone
EGX46_RS22130	COG1070	Carbohydrate kinase
EGX46_RS22140	COG4213	ABC transporter substrate-binding protein
EGX46_RS22150	COG4214	carbohydrate transport
EGX46_RS22155	COG1609	Transcriptional regulator
EGX46_RS22155	COG2207	Transcriptional regulator
EGX46_RS22160	COG0582	viral genome integration into host DNA
EGX46_RS22215	COG4604	ABC transporter, ATP-binding protein
EGX46_RS22220	COG4605	iron ion homeostasis
EGX46_RS22230	COG4607	ABC-type enterochelin transport system periplasmic component
EGX46_RS22275	COG2986	histidine ammonia-lyase
EGX46_RS22290	COG2194	sulfuric ester hydrolase activity
EGX46_RS22295	COG2197	response regulator
EGX46_RS22340	COG0564	pseudouridine synthase activity
EGX46_RS22345	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGX46_RS22395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGX46_RS22405	COG2966	Psort location CytoplasmicMembrane, score
EGX46_RS22410	COG1280	lysine exporter protein (LysE YggA)
EGX46_RS22415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX46_RS22445	COG1047	Peptidyl-prolyl cis-trans
EGX46_RS22460	COG0196	riboflavin kinase activity
EGX46_RS22480	COG0583	DNA-binding transcription factor activity
EGX46_RS22500	COG1584	GPR1 FUN34 yaaH family protein
EGX46_RS22515	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX46_RS22555	COG0745	RESPONSE REGULATOR receiver
EGX46_RS22560	COG3045	CreA protein
EGX46_RS22570	COG2207	Transcriptional regulator
EGX46_RS22570	COG3708	Transcriptional regulator
EGX46_RS22585	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EGX46_RS22590	COG0741	lytic transglycosylase activity
EGX46_RS22605	COG2199	diguanylate cyclase activity
EGX46_RS22610	COG2885	chlorophyll binding
EGX46_RS22645	COG3162	membrane
EGX46_RS22655	COG1301	dicarboxylic acid transport
EGX46_RS22765	COG2391	methyltransferase activity
EGX46_RS22770	COG0425	Belongs to the sulfur carrier protein TusA family
EGX46_RS22775	COG0583	DNA-binding transcription factor activity
EGX46_RS22780	COG0814	amino acid
EGX46_RS22785	COG0626	cystathionine gamma-synthase activity
EGX46_RS22795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX46_RS22800	COG4558	Periplasmic binding protein
EGX46_RS22805	COG3720	iron ion transport
EGX46_RS22810	COG4771	TonB-dependent receptor
EGX46_RS22820	COG0702	epimerase
EGX46_RS22825	COG3721	Heme iron utilization protein
EGX46_RS22850	COG1358	cellular component organization or biogenesis
EGX46_RS22910	COG3121	Chaperone
EGX46_RS22960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGX46_RS22970	COG0735	belongs to the Fur family
EGX46_RS22975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX46_RS23000	COG1448	Aminotransferase
EGX46_RS23005	COG2315	Protein conserved in bacteria
EGX46_RS23010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX46_RS23015	COG0629	single-stranded DNA binding
EGX46_RS23145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX46_RS23160	COG3344	reverse transcriptase
EGX46_RS23185	COG3328	transposase activity
EGX46_RS23295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX46_RS23305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX46_RS23455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX46_RS23460	COG1475	DNA binding
EGX46_RS23465	COG1475	DNA binding
EGX46_RS23595	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX46_RS23595	COG5301	cellulose 1,4-beta-cellobiosidase activity
EGX46_RS23605	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGX46_RS23620	COG1475	DNA binding
EGX46_RS23720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX46_RS23735	COG3344	reverse transcriptase
EGX46_RS23820	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EGX46_RS23830	COG5301	cellulose 1,4-beta-cellobiosidase activity